What is the best way to travel from Rome to Lyon?
Looking for a trip? Check and compare all the available Buses and Flights to Lyon from Rome. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 3 available companies to find your perfect trip!
What is the cheapest way to reach Lyon from Rome?
You can reach Lyon with just £28 by taking a Bus from FlixBus, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
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Itabus14h 30m007:00RomeTiburtina Coach Station21:30LyonPerrache Bus Stop0BasicA Bus from Itabus goes from Tiburtina Coach Station, Rome (Italy) at 05/12/2025 07:00:00 to Perrache Bus Stop, Lyon (France) arriving at 05/12/2025 21:30:00. 50 Basic ticket for £31 per person are available. Travel duration is 14h 30m
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Itabus14h 30m007:00RomeTiburtina Bus Station21:30LyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 05/12/2025 07:00:00 to Perrache Bus Stop, Lyon (France) arriving at 05/12/2025 21:30:00. 50 Premium Economy ticket for £34 per person are available. Travel duration is 14h 30m
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FlixBus14h 55m007:45RomeTiburtina Bus Station22:40LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 05/12/2025 07:45:00 to Perrache Bus Stop, Lyon (France) arriving at 05/12/2025 22:40:00. 50 Economy ticket for £55 per person are available. Travel duration is 14h 55m
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FlixBus14h 55m008:50RomeTiburtina Bus Station23:45LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 05/12/2025 08:50:00 to Perrache Bus Stop, Lyon (France) arriving at 05/12/2025 23:45:00. 50 Economy ticket for £72 per person are available. Travel duration is 14h 55m
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LC Perú10h 5m006:00Rome Fiumicino AirportRome Fiumicino Airport16:05Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from LC Perú goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 05/12/2025 06:00:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 05/12/2025 16:05:00. 50 Economy ticket for £85 per person are available. Travel duration is 10h 5m
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Iberia27h 25m020:20Rome Fiumicino AirportRome Fiumicino Airport23:45Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Iberia goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 05/12/2025 20:20:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 06/12/2025 23:45:00. 50 Economy ticket for £147 per person are available. Travel duration is 27h 25m
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ITA Airways5h 45m009:20Rome Fiumicino AirportRome Fiumicino Airport15:05Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from ITA Airways goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 05/12/2025 09:20:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 05/12/2025 15:05:00. 50 Economy ticket for £157 per person are available. Travel duration is 5h 45m
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EasyJet Airline1h 35m021:20Rome Fiumicino AirportRome Fiumicino Airport22:55Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from EasyJet Airline goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 05/12/2025 21:20:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 05/12/2025 22:55:00. 50 Economy ticket for £159 per person are available. Travel duration is 1h 35m
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KLM - Royal Dutch Airlines25h 50m020:25Rome Fiumicino AirportRome Fiumicino Airport22:15Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from KLM - Royal Dutch Airlines goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 05/12/2025 20:25:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 06/12/2025 22:15:00. 50 Economy ticket for £178 per person are available. Travel duration is 25h 50m
Cheapest Buses Friday
Cheapest Flights Friday
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Itabus14h 30m007:00RomeTiburtina Bus Station21:30LyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 06/12/2025 07:00:00 to Perrache Bus Stop, Lyon (France) arriving at 06/12/2025 21:30:00. 50 Premium Economy ticket for £34 per person are available. Travel duration is 14h 30m
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Itabus15h 10m021:45RomeTiburtina Bus Station12:55LyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 06/12/2025 21:45:00 to Perrache Bus Stop, Lyon (France) arriving at 07/12/2025 12:55:00. 50 Premium Economy ticket for £39 per person are available. Travel duration is 15h 10m
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FlixBus16h 15m021:55RomeTiburtina Bus Station14:10LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 06/12/2025 21:55:00 to Perrache Bus Stop, Lyon (France) arriving at 07/12/2025 14:10:00. 50 Economy ticket for £69 per person are available. Travel duration is 16h 15m
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FlixBus15h 35m023:35RomeAnagnina Bus Station15:10LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 06/12/2025 23:35:00 to Perrache Bus Stop, Lyon (France) arriving at 07/12/2025 15:10:00. 50 Economy ticket for £69 per person are available. Travel duration is 15h 35m
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ITA Airways10h 10m021:25Rome Fiumicino AirportRome Fiumicino Airport07:35Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from ITA Airways goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 06/12/2025 21:25:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 07/12/2025 07:35:00. 50 Economy ticket for £80 per person are available. Travel duration is 10h 10m
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LC Perú12h 35m019:00Rome Fiumicino AirportRome Fiumicino Airport07:35Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from LC Perú goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 06/12/2025 19:00:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 07/12/2025 07:35:00. 50 Economy ticket for £85 per person are available. Travel duration is 12h 35m
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Vueling Airlines17h 30m014:05Rome Fiumicino AirportRome Fiumicino Airport07:35Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Vueling Airlines goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 06/12/2025 14:05:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 07/12/2025 07:35:00. 50 Economy ticket for £87 per person are available. Travel duration is 17h 30m
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Tunisair22h 45m010:20Rome Fiumicino AirportRome Fiumicino Airport09:05Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Tunisair goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 06/12/2025 10:20:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 07/12/2025 09:05:00. 50 Economy ticket for £101 per person are available. Travel duration is 22h 45m
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Air France14h 5m020:45Rome Fiumicino AirportRome Fiumicino Airport10:50Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Air France goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 06/12/2025 20:45:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 07/12/2025 10:50:00. 50 Economy ticket for £103 per person are available. Travel duration is 14h 5m
Cheapest Buses Saturday
Cheapest Flights Saturday
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Itabus14h 30m007:00RomeTiburtina Bus Station21:30LyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 07/12/2025 07:00:00 to Perrache Bus Stop, Lyon (France) arriving at 07/12/2025 21:30:00. 50 Premium Economy ticket for £30 per person are available. Travel duration is 14h 30m
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FlixBus14h 55m007:45RomeTiburtina Bus Station22:40LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 07/12/2025 07:45:00 to Perrache Bus Stop, Lyon (France) arriving at 07/12/2025 22:40:00. 50 Economy ticket for £39 per person are available. Travel duration is 14h 55m
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FlixBus15h 20m017:25RomeAnagnina Bus Station08:45LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 07/12/2025 17:25:00 to Perrache Bus Stop, Lyon (France) arriving at 08/12/2025 08:45:00. 50 Economy ticket for £39 per person are available. Travel duration is 15h 20m
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Wizz Air22h 40m020:40Rome Fiumicino AirportRome Fiumicino Airport19:20Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Wizz Air goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 07/12/2025 20:40:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 08/12/2025 19:20:00. 50 Economy ticket for £68 per person are available. Travel duration is 22h 40m
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Skyscanner9h 30m014:55Rome Fiumicino AirportRome Fiumicino Airport00:25Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Skyscanner goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 07/12/2025 14:55:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 08/12/2025 00:25:00. 50 Economy ticket for £73 per person are available. Travel duration is 9h 30m
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EasyJet Airline1h 35m022:15Rome Fiumicino AirportRome Fiumicino Airport23:50Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from EasyJet Airline goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 07/12/2025 22:15:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 07/12/2025 23:50:00. 50 Economy ticket for £92 per person are available. Travel duration is 1h 35m
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Air Malta11h 45m008:55Rome Fiumicino AirportRome Fiumicino Airport20:40Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Air Malta goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 07/12/2025 08:55:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 07/12/2025 20:40:00. 50 Economy ticket for £105 per person are available. Travel duration is 11h 45m
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Volotea7h 15m016:00Rome Fiumicino AirportRome Fiumicino Airport23:15Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Volotea goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 07/12/2025 16:00:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 07/12/2025 23:15:00. 50 Economy ticket for £131 per person are available. Travel duration is 7h 15m
Cheapest Buses Sunday
Cheapest Flights Sunday
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EasyJet Airline1h 40m009:20Rome Fiumicino AirportRome Fiumicino Airport11:00Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from EasyJet Airline goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 08/12/2025 09:20:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 08/12/2025 11:00:00. 50 Economy ticket for £37 per person are available. Travel duration is 1h 40m
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Skyscanner1h 40m009:20Rome Fiumicino AirportRome Fiumicino Airport11:00Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Skyscanner goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 08/12/2025 09:20:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 08/12/2025 11:00:00. 50 Economy ticket for £46 per person are available. Travel duration is 1h 40m
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LC Perú10h 5m006:00Rome Fiumicino AirportRome Fiumicino Airport16:05Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from LC Perú goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 08/12/2025 06:00:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 08/12/2025 16:05:00. 50 Economy ticket for £69 per person are available. Travel duration is 10h 5m
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Volotea9h 0m014:25Rome Fiumicino AirportRome Fiumicino Airport23:25Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Volotea goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 08/12/2025 14:25:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 08/12/2025 23:25:00. 50 Economy ticket for £75 per person are available. Travel duration is 9h 0m
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ITA Airways5h 55m013:20Rome Fiumicino AirportRome Fiumicino Airport19:15Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from ITA Airways goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 08/12/2025 13:20:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 08/12/2025 19:15:00. 50 Economy ticket for £104 per person are available. Travel duration is 5h 55m
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Itabus15h 10m021:45RomeTiburtina Bus Station12:55LyonPerrache Bus Stop0EconomyA Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 08/12/2025 21:45:00 to Perrache Bus Stop, Lyon (France) arriving at 09/12/2025 12:55:00. 50 Economy ticket for £61 per person are available. Travel duration is 15h 10m
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Itabus18h 55m010:00RomeTiburtina Bus Station04:55LyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 08/12/2025 10:00:00 to Perrache Bus Stop, Lyon (France) arriving at 09/12/2025 04:55:00. 50 Premium Economy ticket for £68 per person are available. Travel duration is 18h 55m
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Itabus14h 30m007:00RomeTiburtina Bus Station21:30LyonPerrache Bus Stop0EconomyA Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 08/12/2025 07:00:00 to Perrache Bus Stop, Lyon (France) arriving at 08/12/2025 21:30:00. 50 Economy ticket for £70 per person are available. Travel duration is 14h 30m
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FlixBus14h 55m007:45RomeTiburtina Bus Station22:40LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 08/12/2025 07:45:00 to Perrache Bus Stop, Lyon (France) arriving at 08/12/2025 22:40:00. 50 Economy ticket for £84 per person are available. Travel duration is 14h 55m
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FlixBus16h 5m000:10RomeTiburtina Bus Station16:15LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 08/12/2025 00:10:00 to Perrache Bus Stop, Lyon (France) arriving at 08/12/2025 16:15:00. 50 Economy ticket for £85 per person are available. Travel duration is 16h 5m
Cheapest Flights Monday
Cheapest Buses Monday
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Itabus15h 10m021:45RomeTiburtina Bus Station12:55LyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 09/12/2025 21:45:00 to Perrache Bus Stop, Lyon (France) arriving at 10/12/2025 12:55:00. 50 Premium Economy ticket for £39 per person are available. Travel duration is 15h 10m
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Itabus14h 30m007:00RomeTiburtina Bus Station21:30LyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 09/12/2025 07:00:00 to Perrache Bus Stop, Lyon (France) arriving at 09/12/2025 21:30:00. 50 Premium Economy ticket for £39 per person are available. Travel duration is 14h 30m
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FlixBus16h 0m020:00RomeTiburtina Bus Station12:00LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 09/12/2025 20:00:00 to Perrache Bus Stop, Lyon (France) arriving at 10/12/2025 12:00:00. 50 Economy ticket for £60 per person are available. Travel duration is 16h 0m
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FlixBus14h 50m013:05RomeAnagnina Bus Station03:55LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 09/12/2025 13:05:00 to Perrache Bus Stop, Lyon (France) arriving at 10/12/2025 03:55:00. 50 Economy ticket for £65 per person are available. Travel duration is 14h 50m
Cheapest Buses Tuesday
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FlixBus15h 20m017:25RomeAnagnina Bus Station08:45LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 10/12/2025 17:25:00 to Perrache Bus Stop, Lyon (France) arriving at 11/12/2025 08:45:00. 50 Economy ticket for £28 per person are available. Travel duration is 15h 20m
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Itabus15h 10m021:45RomeTiburtina Bus Station12:55LyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 10/12/2025 21:45:00 to Perrache Bus Stop, Lyon (France) arriving at 11/12/2025 12:55:00. 50 Premium Economy ticket for £39 per person are available. Travel duration is 15h 10m
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Itabus14h 30m007:00RomeTiburtina Bus Station21:30LyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 10/12/2025 07:00:00 to Perrache Bus Stop, Lyon (France) arriving at 10/12/2025 21:30:00. 50 Premium Economy ticket for £44 per person are available. Travel duration is 14h 30m
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FlixBus16h 0m020:00RomeTiburtina Bus Station12:00LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 10/12/2025 20:00:00 to Perrache Bus Stop, Lyon (France) arriving at 11/12/2025 12:00:00. 50 Economy ticket for £53 per person are available. Travel duration is 16h 0m
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EasyJet Airline1h 40m010:30Rome Fiumicino AirportRome Fiumicino Airport12:10Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from EasyJet Airline goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 10/12/2025 10:30:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 10/12/2025 12:10:00. 50 Economy ticket for £29 per person are available. Travel duration is 1h 40m
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Skyscanner1h 40m010:30Rome Fiumicino AirportRome Fiumicino Airport12:10Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Skyscanner goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 10/12/2025 10:30:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 10/12/2025 12:10:00. 50 Economy ticket for £39 per person are available. Travel duration is 1h 40m
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Vueling Airlines12h 5m019:30Rome Fiumicino AirportRome Fiumicino Airport07:35Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Vueling Airlines goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 10/12/2025 19:30:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 11/12/2025 07:35:00. 50 Economy ticket for £54 per person are available. Travel duration is 12h 5m
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LC Perú22h 40m022:15Rome Fiumicino AirportRome Fiumicino Airport20:55Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from LC Perú goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 10/12/2025 22:15:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 11/12/2025 20:55:00. 50 Economy ticket for £56 per person are available. Travel duration is 22h 40m
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Air Malta23h 40m021:00Rome Fiumicino AirportRome Fiumicino Airport20:40Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Air Malta goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 10/12/2025 21:00:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 11/12/2025 20:40:00. 50 Economy ticket for £105 per person are available. Travel duration is 23h 40m
Cheapest Buses Wednesday
Cheapest Flights Wednesday
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EasyJet Airline1h 40m010:30Rome Fiumicino AirportRome Fiumicino Airport12:10Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from EasyJet Airline goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 11/12/2025 10:30:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 11/12/2025 12:10:00. 50 Economy ticket for £29 per person are available. Travel duration is 1h 40m
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Skyscanner1h 40m010:30Rome Fiumicino AirportRome Fiumicino Airport12:10Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Skyscanner goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 11/12/2025 10:30:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 11/12/2025 12:10:00. 50 Economy ticket for £32 per person are available. Travel duration is 1h 40m
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Vueling Airlines12h 45m019:10Rome Fiumicino AirportRome Fiumicino Airport07:55Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Vueling Airlines goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 11/12/2025 19:10:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 12/12/2025 07:55:00. 50 Economy ticket for £72 per person are available. Travel duration is 12h 45m
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LC Perú4h 35m007:25Rome Fiumicino AirportRome Fiumicino Airport12:00Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from LC Perú goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 11/12/2025 07:25:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 11/12/2025 12:00:00. 50 Economy ticket for £80 per person are available. Travel duration is 4h 35m
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Iberia11h 45m012:00Rome Fiumicino AirportRome Fiumicino Airport23:45Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Iberia goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 11/12/2025 12:00:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 11/12/2025 23:45:00. 50 Economy ticket for £80 per person are available. Travel duration is 11h 45m
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Itabus15h 10m021:45RomeTiburtina Bus Station12:55LyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 11/12/2025 21:45:00 to Perrache Bus Stop, Lyon (France) arriving at 12/12/2025 12:55:00. 50 Premium Economy ticket for £30 per person are available. Travel duration is 15h 10m
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FlixBus14h 55m007:45RomeTiburtina Bus Station22:40LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 11/12/2025 07:45:00 to Perrache Bus Stop, Lyon (France) arriving at 11/12/2025 22:40:00. 50 Economy ticket for £42 per person are available. Travel duration is 14h 55m
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FlixBus14h 55m008:50RomeTiburtina Bus Station23:45LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 11/12/2025 08:50:00 to Perrache Bus Stop, Lyon (France) arriving at 11/12/2025 23:45:00. 50 Economy ticket for £45 per person are available. Travel duration is 14h 55m
Cheapest Flights Thursday
Cheapest Buses Thursday
What are the fastest trips from Rome to Lyon?
You can get to Lyon from Rome in just 1h 35m with a Flight from EasyJet Airline. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
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EasyJet Airline1h 35m021:20Rome Fiumicino AirportRome Fiumicino Airport22:55Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from EasyJet Airline goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 05/12/2025 21:20:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 05/12/2025 22:55:00. 50 Economy ticket for £159 per person are available. Travel duration is 1h 35m
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ITA Airways5h 45m009:20Rome Fiumicino AirportRome Fiumicino Airport15:05Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from ITA Airways goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 05/12/2025 09:20:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 05/12/2025 15:05:00. 50 Economy ticket for £157 per person are available. Travel duration is 5h 45m
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LC Perú10h 5m006:00Rome Fiumicino AirportRome Fiumicino Airport16:05Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from LC Perú goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 05/12/2025 06:00:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 05/12/2025 16:05:00. 50 Economy ticket for £85 per person are available. Travel duration is 10h 5m
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KLM - Royal Dutch Airlines25h 50m020:25Rome Fiumicino AirportRome Fiumicino Airport22:15Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from KLM - Royal Dutch Airlines goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 05/12/2025 20:25:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 06/12/2025 22:15:00. 50 Economy ticket for £178 per person are available. Travel duration is 25h 50m
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Iberia27h 25m020:20Rome Fiumicino AirportRome Fiumicino Airport23:45Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Iberia goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 05/12/2025 20:20:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 06/12/2025 23:45:00. 50 Economy ticket for £147 per person are available. Travel duration is 27h 25m
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Itabus14h 30m007:00RomeTiburtina Coach Station21:30LyonPerrache Bus Stop0BasicA Bus from Itabus goes from Tiburtina Coach Station, Rome (Italy) at 05/12/2025 07:00:00 to Perrache Bus Stop, Lyon (France) arriving at 05/12/2025 21:30:00. 50 Basic ticket for £31 per person are available. Travel duration is 14h 30m
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Itabus14h 30m007:00RomeTiburtina Bus Station21:30LyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 05/12/2025 07:00:00 to Perrache Bus Stop, Lyon (France) arriving at 05/12/2025 21:30:00. 50 Premium Economy ticket for £34 per person are available. Travel duration is 14h 30m
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FlixBus14h 55m007:45RomeTiburtina Bus Station22:40LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 05/12/2025 07:45:00 to Perrache Bus Stop, Lyon (France) arriving at 05/12/2025 22:40:00. 50 Economy ticket for £55 per person are available. Travel duration is 14h 55m
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FlixBus14h 55m008:50RomeTiburtina Bus Station23:45LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 05/12/2025 08:50:00 to Perrache Bus Stop, Lyon (France) arriving at 05/12/2025 23:45:00. 50 Economy ticket for £72 per person are available. Travel duration is 14h 55m
Fastest Flights Friday
Fastest Buses Friday
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ITA Airways10h 10m021:25Rome Fiumicino AirportRome Fiumicino Airport07:35Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from ITA Airways goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 06/12/2025 21:25:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 07/12/2025 07:35:00. 50 Economy ticket for £80 per person are available. Travel duration is 10h 10m
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LC Perú12h 35m019:00Rome Fiumicino AirportRome Fiumicino Airport07:35Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from LC Perú goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 06/12/2025 19:00:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 07/12/2025 07:35:00. 50 Economy ticket for £85 per person are available. Travel duration is 12h 35m
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Air France14h 5m020:45Rome Fiumicino AirportRome Fiumicino Airport10:50Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Air France goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 06/12/2025 20:45:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 07/12/2025 10:50:00. 50 Economy ticket for £103 per person are available. Travel duration is 14h 5m
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Vueling Airlines17h 30m014:05Rome Fiumicino AirportRome Fiumicino Airport07:35Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Vueling Airlines goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 06/12/2025 14:05:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 07/12/2025 07:35:00. 50 Economy ticket for £87 per person are available. Travel duration is 17h 30m
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Tunisair22h 45m010:20Rome Fiumicino AirportRome Fiumicino Airport09:05Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Tunisair goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 06/12/2025 10:20:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 07/12/2025 09:05:00. 50 Economy ticket for £101 per person are available. Travel duration is 22h 45m
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Itabus14h 30m007:00RomeTiburtina Bus Station21:30LyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 06/12/2025 07:00:00 to Perrache Bus Stop, Lyon (France) arriving at 06/12/2025 21:30:00. 50 Premium Economy ticket for £34 per person are available. Travel duration is 14h 30m
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Itabus15h 10m021:45RomeTiburtina Bus Station12:55LyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 06/12/2025 21:45:00 to Perrache Bus Stop, Lyon (France) arriving at 07/12/2025 12:55:00. 50 Premium Economy ticket for £39 per person are available. Travel duration is 15h 10m
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FlixBus15h 35m023:35RomeAnagnina Bus Station15:10LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 06/12/2025 23:35:00 to Perrache Bus Stop, Lyon (France) arriving at 07/12/2025 15:10:00. 50 Economy ticket for £69 per person are available. Travel duration is 15h 35m
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FlixBus16h 15m021:55RomeTiburtina Bus Station14:10LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 06/12/2025 21:55:00 to Perrache Bus Stop, Lyon (France) arriving at 07/12/2025 14:10:00. 50 Economy ticket for £69 per person are available. Travel duration is 16h 15m
Fastest Flights Saturday
Fastest Buses Saturday
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EasyJet Airline1h 35m022:15Rome Fiumicino AirportRome Fiumicino Airport23:50Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from EasyJet Airline goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 07/12/2025 22:15:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 07/12/2025 23:50:00. 50 Economy ticket for £92 per person are available. Travel duration is 1h 35m
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Volotea7h 15m016:00Rome Fiumicino AirportRome Fiumicino Airport23:15Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Volotea goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 07/12/2025 16:00:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 07/12/2025 23:15:00. 50 Economy ticket for £131 per person are available. Travel duration is 7h 15m
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Skyscanner9h 30m014:55Rome Fiumicino AirportRome Fiumicino Airport00:25Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Skyscanner goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 07/12/2025 14:55:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 08/12/2025 00:25:00. 50 Economy ticket for £73 per person are available. Travel duration is 9h 30m
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Air Malta11h 45m008:55Rome Fiumicino AirportRome Fiumicino Airport20:40Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Air Malta goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 07/12/2025 08:55:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 07/12/2025 20:40:00. 50 Economy ticket for £105 per person are available. Travel duration is 11h 45m
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Wizz Air22h 40m020:40Rome Fiumicino AirportRome Fiumicino Airport19:20Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Wizz Air goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 07/12/2025 20:40:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 08/12/2025 19:20:00. 50 Economy ticket for £68 per person are available. Travel duration is 22h 40m
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Itabus14h 30m007:00RomeTiburtina Bus Station21:30LyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 07/12/2025 07:00:00 to Perrache Bus Stop, Lyon (France) arriving at 07/12/2025 21:30:00. 50 Premium Economy ticket for £30 per person are available. Travel duration is 14h 30m
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FlixBus14h 55m007:45RomeTiburtina Bus Station22:40LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 07/12/2025 07:45:00 to Perrache Bus Stop, Lyon (France) arriving at 07/12/2025 22:40:00. 50 Economy ticket for £39 per person are available. Travel duration is 14h 55m
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FlixBus15h 20m017:25RomeAnagnina Bus Station08:45LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 07/12/2025 17:25:00 to Perrache Bus Stop, Lyon (France) arriving at 08/12/2025 08:45:00. 50 Economy ticket for £39 per person are available. Travel duration is 15h 20m
Fastest Flights Sunday
Fastest Buses Sunday
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EasyJet Airline1h 40m009:20Rome Fiumicino AirportRome Fiumicino Airport11:00Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from EasyJet Airline goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 08/12/2025 09:20:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 08/12/2025 11:00:00. 50 Economy ticket for £37 per person are available. Travel duration is 1h 40m
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Skyscanner1h 40m009:20Rome Fiumicino AirportRome Fiumicino Airport11:00Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Skyscanner goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 08/12/2025 09:20:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 08/12/2025 11:00:00. 50 Economy ticket for £46 per person are available. Travel duration is 1h 40m
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ITA Airways5h 55m013:20Rome Fiumicino AirportRome Fiumicino Airport19:15Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from ITA Airways goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 08/12/2025 13:20:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 08/12/2025 19:15:00. 50 Economy ticket for £104 per person are available. Travel duration is 5h 55m
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Volotea9h 0m014:25Rome Fiumicino AirportRome Fiumicino Airport23:25Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Volotea goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 08/12/2025 14:25:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 08/12/2025 23:25:00. 50 Economy ticket for £75 per person are available. Travel duration is 9h 0m
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LC Perú10h 5m006:00Rome Fiumicino AirportRome Fiumicino Airport16:05Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from LC Perú goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 08/12/2025 06:00:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 08/12/2025 16:05:00. 50 Economy ticket for £69 per person are available. Travel duration is 10h 5m
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Itabus14h 30m007:00RomeTiburtina Bus Station21:30LyonPerrache Bus Stop0EconomyA Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 08/12/2025 07:00:00 to Perrache Bus Stop, Lyon (France) arriving at 08/12/2025 21:30:00. 50 Economy ticket for £70 per person are available. Travel duration is 14h 30m
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FlixBus14h 55m007:45RomeTiburtina Bus Station22:40LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 08/12/2025 07:45:00 to Perrache Bus Stop, Lyon (France) arriving at 08/12/2025 22:40:00. 50 Economy ticket for £84 per person are available. Travel duration is 14h 55m
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Itabus15h 10m021:45RomeTiburtina Bus Station12:55LyonPerrache Bus Stop0EconomyA Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 08/12/2025 21:45:00 to Perrache Bus Stop, Lyon (France) arriving at 09/12/2025 12:55:00. 50 Economy ticket for £61 per person are available. Travel duration is 15h 10m
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FlixBus16h 5m000:10RomeTiburtina Bus Station16:15LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 08/12/2025 00:10:00 to Perrache Bus Stop, Lyon (France) arriving at 08/12/2025 16:15:00. 50 Economy ticket for £85 per person are available. Travel duration is 16h 5m
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Itabus18h 55m010:00RomeTiburtina Bus Station04:55LyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 08/12/2025 10:00:00 to Perrache Bus Stop, Lyon (France) arriving at 09/12/2025 04:55:00. 50 Premium Economy ticket for £68 per person are available. Travel duration is 18h 55m
Fastest Flights Monday
Fastest Buses Monday
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Itabus14h 30m007:00RomeTiburtina Bus Station21:30LyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 09/12/2025 07:00:00 to Perrache Bus Stop, Lyon (France) arriving at 09/12/2025 21:30:00. 50 Premium Economy ticket for £39 per person are available. Travel duration is 14h 30m
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FlixBus14h 50m013:05RomeAnagnina Bus Station03:55LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 09/12/2025 13:05:00 to Perrache Bus Stop, Lyon (France) arriving at 10/12/2025 03:55:00. 50 Economy ticket for £65 per person are available. Travel duration is 14h 50m
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Itabus15h 10m021:45RomeTiburtina Bus Station12:55LyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 09/12/2025 21:45:00 to Perrache Bus Stop, Lyon (France) arriving at 10/12/2025 12:55:00. 50 Premium Economy ticket for £39 per person are available. Travel duration is 15h 10m
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FlixBus16h 0m020:00RomeTiburtina Bus Station12:00LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 09/12/2025 20:00:00 to Perrache Bus Stop, Lyon (France) arriving at 10/12/2025 12:00:00. 50 Economy ticket for £60 per person are available. Travel duration is 16h 0m
Fastest Buses Tuesday
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EasyJet Airline1h 40m010:30Rome Fiumicino AirportRome Fiumicino Airport12:10Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from EasyJet Airline goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 10/12/2025 10:30:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 10/12/2025 12:10:00. 50 Economy ticket for £29 per person are available. Travel duration is 1h 40m
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Skyscanner1h 40m010:30Rome Fiumicino AirportRome Fiumicino Airport12:10Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Skyscanner goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 10/12/2025 10:30:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 10/12/2025 12:10:00. 50 Economy ticket for £39 per person are available. Travel duration is 1h 40m
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Vueling Airlines12h 5m019:30Rome Fiumicino AirportRome Fiumicino Airport07:35Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Vueling Airlines goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 10/12/2025 19:30:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 11/12/2025 07:35:00. 50 Economy ticket for £54 per person are available. Travel duration is 12h 5m
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LC Perú22h 40m022:15Rome Fiumicino AirportRome Fiumicino Airport20:55Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from LC Perú goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 10/12/2025 22:15:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 11/12/2025 20:55:00. 50 Economy ticket for £56 per person are available. Travel duration is 22h 40m
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Air Malta23h 40m021:00Rome Fiumicino AirportRome Fiumicino Airport20:40Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Air Malta goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 10/12/2025 21:00:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 11/12/2025 20:40:00. 50 Economy ticket for £105 per person are available. Travel duration is 23h 40m
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Itabus14h 30m007:00RomeTiburtina Bus Station21:30LyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 10/12/2025 07:00:00 to Perrache Bus Stop, Lyon (France) arriving at 10/12/2025 21:30:00. 50 Premium Economy ticket for £44 per person are available. Travel duration is 14h 30m
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Itabus15h 10m021:45RomeTiburtina Bus Station12:55LyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 10/12/2025 21:45:00 to Perrache Bus Stop, Lyon (France) arriving at 11/12/2025 12:55:00. 50 Premium Economy ticket for £39 per person are available. Travel duration is 15h 10m
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FlixBus15h 20m017:25RomeAnagnina Bus Station08:45LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 10/12/2025 17:25:00 to Perrache Bus Stop, Lyon (France) arriving at 11/12/2025 08:45:00. 50 Economy ticket for £28 per person are available. Travel duration is 15h 20m
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FlixBus16h 0m020:00RomeTiburtina Bus Station12:00LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 10/12/2025 20:00:00 to Perrache Bus Stop, Lyon (France) arriving at 11/12/2025 12:00:00. 50 Economy ticket for £53 per person are available. Travel duration is 16h 0m
Fastest Flights Wednesday
Fastest Buses Wednesday
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EasyJet Airline1h 40m010:30Rome Fiumicino AirportRome Fiumicino Airport12:10Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from EasyJet Airline goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 11/12/2025 10:30:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 11/12/2025 12:10:00. 50 Economy ticket for £29 per person are available. Travel duration is 1h 40m
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Skyscanner1h 40m010:30Rome Fiumicino AirportRome Fiumicino Airport12:10Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Skyscanner goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 11/12/2025 10:30:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 11/12/2025 12:10:00. 50 Economy ticket for £32 per person are available. Travel duration is 1h 40m
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LC Perú4h 35m007:25Rome Fiumicino AirportRome Fiumicino Airport12:00Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from LC Perú goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 11/12/2025 07:25:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 11/12/2025 12:00:00. 50 Economy ticket for £80 per person are available. Travel duration is 4h 35m
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Iberia11h 45m012:00Rome Fiumicino AirportRome Fiumicino Airport23:45Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Iberia goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 11/12/2025 12:00:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 11/12/2025 23:45:00. 50 Economy ticket for £80 per person are available. Travel duration is 11h 45m
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Vueling Airlines12h 45m019:10Rome Fiumicino AirportRome Fiumicino Airport07:55Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Vueling Airlines goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 11/12/2025 19:10:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 12/12/2025 07:55:00. 50 Economy ticket for £72 per person are available. Travel duration is 12h 45m
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FlixBus14h 55m007:45RomeTiburtina Bus Station22:40LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 11/12/2025 07:45:00 to Perrache Bus Stop, Lyon (France) arriving at 11/12/2025 22:40:00. 50 Economy ticket for £42 per person are available. Travel duration is 14h 55m
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FlixBus14h 55m008:50RomeTiburtina Bus Station23:45LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 11/12/2025 08:50:00 to Perrache Bus Stop, Lyon (France) arriving at 11/12/2025 23:45:00. 50 Economy ticket for £45 per person are available. Travel duration is 14h 55m
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Itabus15h 10m021:45RomeTiburtina Bus Station12:55LyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 11/12/2025 21:45:00 to Perrache Bus Stop, Lyon (France) arriving at 12/12/2025 12:55:00. 50 Premium Economy ticket for £30 per person are available. Travel duration is 15h 10m
Fastest Flights Thursday
Fastest Buses Thursday
Here you will find all operators and timetables for a
Bus from Rome to Lyon
What are the most popular stations in Rome and Lyon?
In Rome, you will usually depart from Termini Bus Station, Termini Central Station or Ostiense Train Station, while in Lyon you will be arriving at Perrache Bus Stop, Part-Dieu Train Station or Perrache Train Station, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Lyon from Rome? With 9 connections between 3 Bus and Flight operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Rome and Lyon, you can pay as low as £28 with a Bus from FlixBus.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from EasyJet Airline: you will get to Lyon in just 1h 35m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Rome and Lyon are Itabus, FlixBus and LC Perú, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Rome and Lyon is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Settebagni or to Caluire-et-Cuire, and look at flights from Rome Ciampino Airport, and landing at Lyons St. Exupery Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Rome to Lyon?
The most popular companies between Rome and Lyon, are Itabus, FlixBus and LC Perú. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: Itabus and FlixBus
Airlines: LC Perú, EasyJet Airline, Skyscanner and 9 more.
All you need to know when you travel from Rome to Lyon
Check all information on comfort and services on all modes of transports from Rome to Lyon. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Rome to Lyon
How can I reach Lyon from Rome?
Every day, there are on average 9 connections between Bus and Flight, with which you can get to Lyon from Rome.
How far is Lyon from Rome?
The distance between Rome and Lyon is 749.0 km.
What is the most ecofriendly mode of transport between Rome and Lyon?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 20 kgs of CO2, a train 26 kgs, a car 127 kgs, and a flight 184 kgs.
What is the cheapest mode of transport from Rome to Lyon?
You can get to Lyon with just £28 by taking a Bus from FlixBus.
What is the fastest way to get from Rome to Lyon?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Lyon in just 1h 35m with a Flight from EasyJet Airline.
More routes to Rome and to Lyon
Looking for more options? Here you can see the most popular routes to Rome and to Lyon. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Rome
- Avellino to Rome
- Bari to Rome
- Battipaglia to Rome
- Caserta to Rome
- Catanzaro to Rome
- Chieti to Rome
- Civitanova to Rome
- Foggia to Rome
- Genoa to Rome
- L'Aquila to Rome
- Lamezia Terme to Rome
- Lecce to Rome
- Milan to Rome
- Mosciano Sant'Angelo to Rome
- Naples to Rome
- Palermo to Rome
- Perugia to Rome
- Pescara to Rome
- Potenza to Rome
- Rome Fiumicino Airport to Rome
- Sala Consilina to Rome
- Salerno to Rome
- San Benedetto del Tronto to Rome
- Venice to Rome
- Trips to Lyon
- Alicante to Lyon
- Annecy to Lyon
- Basel to Lyon
- Bern to Lyon
- Braga to Lyon
- Caen to Lyon
- Dijon to Lyon
- Geneva Airport to Lyon
- Geneva to Lyon
- Liege to Lyon
- Lisbon to Lyon
- London to Lyon
- Lyons St. Exupery Airport to Lyon
- Madrid to Lyon
- Marseille to Lyon
- Nantes to Lyon
- Nice to Lyon
- Perpignan to Lyon
- Poitiers to Lyon
- Sallanches to Lyon
- Toulouse to Lyon
- Turin to Lyon
- Valencia to Lyon
- Zurich to Lyon

