What is the best way to travel from Milan to Lyon?
Looking for a trip? Check and compare all the available Trains, Flights, Carpool and Buses to Lyon from Milan. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 7 available companies to find your perfect trip!
What is the cheapest way to reach Lyon from Milan?
You can reach Lyon with just £12 by taking a Bus from Itabus, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
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Itabus6h 35m014:55MilanLampugnano Bus Station21:30LyonPerrache Bus Stop0EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 22/06/2026 14:55:00 to Perrache Bus Stop, Lyon (France) arriving at 22/06/2026 21:30:00. 50 Economy ticket for £14 per person are available. Travel duration is 6h 35m
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Itabus6h 35m017:50MilanLampugnano Bus Station00:25LyonPerrache Bus Stop0EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 22/06/2026 17:50:00 to Perrache Bus Stop, Lyon (France) arriving at 23/06/2026 00:25:00. 50 Economy ticket for £14 per person are available. Travel duration is 6h 35m
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BlaBlaCar Bus8h 15m010:35MilanLampugnano Bus Station18:50LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Lampugnano Bus Station, Milan (Italy) at 22/06/2026 10:35:00 to Perrache Train Station, Lyon (France) arriving at 22/06/2026 18:50:00. 50 Economy ticket for £30 per person are available. Travel duration is 8h 15m
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Lauda Europe11h 10m022:50Milan Malpensa AirportMilan Malpensa Airport10:00Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Lauda Europe goes from Milan Malpensa Airport, Milan Malpensa Airport (Italy) at 22/06/2026 22:50:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 23/06/2026 10:00:00. 50 Economy ticket for £43 per person are available. Travel duration is 11h 10m
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Skyscanner5h 45m006:55Bergamo AirportBergamo Airport12:40Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Skyscanner goes from Bergamo Airport, Bergamo Airport (Italy) at 22/06/2026 06:55:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 22/06/2026 12:40:00. 50 Economy ticket for £55 per person are available. Travel duration is 5h 45m
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EasyJet Airline6h 55m007:00Milan Linate AirportMilan Linate Airport13:55Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from EasyJet Airline goes from Milan Linate Airport, Milan Linate Airport (Italy) at 22/06/2026 07:00:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 22/06/2026 13:55:00. 50 Economy ticket for £59 per person are available. Travel duration is 6h 55m
Cheapest Buses Monday
Cheapest Flights Monday
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Itabus6h 35m006:20MilanLampugnano Bus Station12:55LyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 23/06/2026 06:20:00 to Perrache Bus Stop, Lyon (France) arriving at 23/06/2026 12:55:00. 50 Premium Economy ticket for £13 per person are available. Travel duration is 6h 35m
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Itabus6h 35m014:55MilanLampugnano Bus Station21:30LyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 23/06/2026 14:55:00 to Perrache Bus Stop, Lyon (France) arriving at 23/06/2026 21:30:00. 50 Premium Economy ticket for £13 per person are available. Travel duration is 6h 35m
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BlaBlaCar Bus6h 55m016:00MilanLampugnano Bus Station22:55LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Lampugnano Bus Station, Milan (Italy) at 23/06/2026 16:00:00 to Perrache Train Station, Lyon (France) arriving at 23/06/2026 22:55:00. 50 Economy ticket for £23 per person are available. Travel duration is 6h 55m
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Skyscanner9h 15m006:45Milan Malpensa AirportMilan Malpensa Airport16:00Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Skyscanner goes from Milan Malpensa Airport, Milan Malpensa Airport (Italy) at 23/06/2026 06:45:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 23/06/2026 16:00:00. 50 Economy ticket for £33 per person are available. Travel duration is 9h 15m
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EasyJet Airline16h 20m007:00Milan Malpensa AirportMilan Malpensa Airport23:20Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from EasyJet Airline goes from Milan Malpensa Airport, Milan Malpensa Airport (Italy) at 23/06/2026 07:00:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 23/06/2026 23:20:00. 50 Economy ticket for £49 per person are available. Travel duration is 16h 20m
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LC Perú7h 30m010:45Milan Malpensa AirportMilan Malpensa Airport18:15Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from LC Perú goes from Milan Malpensa Airport, Milan Malpensa Airport (Italy) at 23/06/2026 10:45:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 23/06/2026 18:15:00. 50 Economy ticket for £54 per person are available. Travel duration is 7h 30m
Cheapest Buses Tuesday
Cheapest Flights Tuesday
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Itabus6h 35m006:20MilanLampugnano Bus Station12:55LyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 24/06/2026 06:20:00 to Perrache Bus Stop, Lyon (France) arriving at 24/06/2026 12:55:00. 50 Premium Economy ticket for £13 per person are available. Travel duration is 6h 35m
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Union Ivkoni8h 15m006:00MilanLampugnano Bus Station14:15LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from Union Ivkoni goes from Lampugnano Bus Station, Milan (Italy) at 24/06/2026 06:00:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 24/06/2026 14:15:00. 50 Economy ticket for £23 per person are available. Travel duration is 8h 15m
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BlaBlaCar Bus6h 55m016:00MilanLampugnano Bus Station22:55LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Lampugnano Bus Station, Milan (Italy) at 24/06/2026 16:00:00 to Perrache Train Station, Lyon (France) arriving at 24/06/2026 22:55:00. 50 Economy ticket for £23 per person are available. Travel duration is 6h 55m
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LC Perú12h 40m019:55Milan Malpensa AirportMilan Malpensa Airport08:35Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from LC Perú goes from Milan Malpensa Airport, Milan Malpensa Airport (Italy) at 24/06/2026 19:55:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 25/06/2026 08:35:00. 50 Economy ticket for £48 per person are available. Travel duration is 12h 40m
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EasyJet Airline9h 15m023:20Milan Malpensa AirportMilan Malpensa Airport08:35Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from EasyJet Airline goes from Milan Malpensa Airport, Milan Malpensa Airport (Italy) at 24/06/2026 23:20:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 25/06/2026 08:35:00. 50 Economy ticket for £77 per person are available. Travel duration is 9h 15m
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Vueling Airlines5h 40m018:25Milan Malpensa AirportMilan Malpensa Airport00:05Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Vueling Airlines goes from Milan Malpensa Airport, Milan Malpensa Airport (Italy) at 24/06/2026 18:25:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 25/06/2026 00:05:00. 50 Economy ticket for £103 per person are available. Travel duration is 5h 40m
Cheapest Buses Wednesday
Cheapest Flights Wednesday
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Itabus6h 35m014:55MilanLampugnano Bus Station21:30LyonPerrache Bus Stop0EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 25/06/2026 14:55:00 to Perrache Bus Stop, Lyon (France) arriving at 25/06/2026 21:30:00. 50 Economy ticket for £12 per person are available. Travel duration is 6h 35m
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Itabus6h 35m006:20MilanLampugnano Bus Station12:55LyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 25/06/2026 06:20:00 to Perrache Bus Stop, Lyon (France) arriving at 25/06/2026 12:55:00. 50 Premium Economy ticket for £13 per person are available. Travel duration is 6h 35m
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BlaBlaCar Bus6h 45m010:20MilanLampugnano Bus Station17:05LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Lampugnano Bus Station, Milan (Italy) at 25/06/2026 10:20:00 to Perrache Train Station, Lyon (France) arriving at 25/06/2026 17:05:00. 50 Economy ticket for £23 per person are available. Travel duration is 6h 45m
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BlaBlaCar5h 1m022:30Milan03:30Lyon0EconomyA Car from BlaBlaCar goes from , Milan (Italy) at 25/06/2026 22:30:00 to , Lyon (France) arriving at 26/06/2026 03:30:00. 50 Economy ticket for £25 per person are available. Travel duration is 5h 1m
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TGV Lyria6h 0m016:10MilanPorta Garibaldi Train Station22:10LyonPart-Dieu Train Station0EconomyA Train from TGV Lyria goes from Porta Garibaldi Train Station, Milan (Italy) at 25/06/2026 16:10:00 to Part-Dieu Train Station, Lyon (France) arriving at 25/06/2026 22:10:00. 50 Economy ticket for £86 per person are available. Travel duration is 6h 0m
Cheapest Buses Thursday
Cheapest Carpool Thursday
Cheapest Trains Thursday
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Itabus6h 35m006:20MilanLampugnano Bus Station12:55LyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 26/06/2026 06:20:00 to Perrache Bus Stop, Lyon (France) arriving at 26/06/2026 12:55:00. 50 Premium Economy ticket for £13 per person are available. Travel duration is 6h 35m
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Union Ivkoni8h 15m006:00MilanLampugnano Bus Station14:15LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from Union Ivkoni goes from Lampugnano Bus Station, Milan (Italy) at 26/06/2026 06:00:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 26/06/2026 14:15:00. 50 Economy ticket for £23 per person are available. Travel duration is 8h 15m
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FlixBus7h 10m009:15MilanLampugnano Bus Station16:25LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 26/06/2026 09:15:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 26/06/2026 16:25:00. 50 Economy ticket for £28 per person are available. Travel duration is 7h 10m
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LC Perú23h 30m008:45Milan Malpensa AirportMilan Malpensa Airport08:15Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from LC Perú goes from Milan Malpensa Airport, Milan Malpensa Airport (Italy) at 26/06/2026 08:45:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 27/06/2026 08:15:00. 50 Economy ticket for £82 per person are available. Travel duration is 23h 30m
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EasyJet Airline6h 10m017:40Milan Malpensa AirportMilan Malpensa Airport23:50Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from EasyJet Airline goes from Milan Malpensa Airport, Milan Malpensa Airport (Italy) at 26/06/2026 17:40:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 26/06/2026 23:50:00. 50 Economy ticket for £105 per person are available. Travel duration is 6h 10m
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Air Malta7h 15m015:35Milan Linate AirportMilan Linate Airport22:50Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Air Malta goes from Milan Linate Airport, Milan Linate Airport (Italy) at 26/06/2026 15:35:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 26/06/2026 22:50:00. 50 Economy ticket for £108 per person are available. Travel duration is 7h 15m
Cheapest Buses Friday
Cheapest Flights Friday
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Itabus6h 35m006:20MilanLampugnano Bus Station12:55LyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 27/06/2026 06:20:00 to Perrache Bus Stop, Lyon (France) arriving at 27/06/2026 12:55:00. 50 Premium Economy ticket for £17 per person are available. Travel duration is 6h 35m
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Itabus6h 35m014:55MilanLampugnano Bus Station21:30LyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 27/06/2026 14:55:00 to Perrache Bus Stop, Lyon (France) arriving at 27/06/2026 21:30:00. 50 Premium Economy ticket for £17 per person are available. Travel duration is 6h 35m
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BlaBlaCar Bus6h 45m010:20MilanLampugnano Bus Station17:05LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Lampugnano Bus Station, Milan (Italy) at 27/06/2026 10:20:00 to Perrache Train Station, Lyon (France) arriving at 27/06/2026 17:05:00. 50 Economy ticket for £25 per person are available. Travel duration is 6h 45m
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EasyJet Airline26h 50m020:35Milan Malpensa AirportMilan Malpensa Airport23:25Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from EasyJet Airline goes from Milan Malpensa Airport, Milan Malpensa Airport (Italy) at 27/06/2026 20:35:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 28/06/2026 23:25:00. 50 Economy ticket for £73 per person are available. Travel duration is 26h 50m
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LC Perú7h 45m018:15Milan Malpensa AirportMilan Malpensa Airport02:00Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from LC Perú goes from Milan Malpensa Airport, Milan Malpensa Airport (Italy) at 27/06/2026 18:15:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 28/06/2026 02:00:00. 50 Economy ticket for £100 per person are available. Travel duration is 7h 45m
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Vueling Airlines11h 40m011:10Milan Malpensa AirportMilan Malpensa Airport22:50Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Vueling Airlines goes from Milan Malpensa Airport, Milan Malpensa Airport (Italy) at 27/06/2026 11:10:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 27/06/2026 22:50:00. 50 Economy ticket for £118 per person are available. Travel duration is 11h 40m
Cheapest Buses Saturday
Cheapest Flights Saturday
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Itabus6h 35m006:20MilanLampugnano Bus Station12:55LyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 28/06/2026 06:20:00 to Perrache Bus Stop, Lyon (France) arriving at 28/06/2026 12:55:00. 50 Premium Economy ticket for £13 per person are available. Travel duration is 6h 35m
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Union Ivkoni8h 15m006:45MilanLampugnano Bus Station15:00LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from Union Ivkoni goes from Lampugnano Bus Station, Milan (Italy) at 28/06/2026 06:45:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 28/06/2026 15:00:00. 50 Economy ticket for £23 per person are available. Travel duration is 8h 15m
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BlaBlaCar Bus6h 45m010:20MilanLampugnano Bus Station17:05LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Lampugnano Bus Station, Milan (Italy) at 28/06/2026 10:20:00 to Perrache Train Station, Lyon (France) arriving at 28/06/2026 17:05:00. 50 Economy ticket for £28 per person are available. Travel duration is 6h 45m
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LC Perú24h 45m015:45Bergamo AirportBergamo Airport16:30Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from LC Perú goes from Bergamo Airport, Bergamo Airport (Italy) at 28/06/2026 15:45:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 29/06/2026 16:30:00. 50 Economy ticket for £27 per person are available. Travel duration is 24h 45m
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Ryanair12h 20m022:50Bergamo AirportBergamo Airport11:10Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Ryanair goes from Bergamo Airport, Bergamo Airport (Italy) at 28/06/2026 22:50:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 29/06/2026 11:10:00. 50 Economy ticket for £49 per person are available. Travel duration is 12h 20m
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EasyJet Airline7h 50m006:00Milan Malpensa AirportMilan Malpensa Airport13:50Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from EasyJet Airline goes from Milan Malpensa Airport, Milan Malpensa Airport (Italy) at 28/06/2026 06:00:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 28/06/2026 13:50:00. 50 Economy ticket for £104 per person are available. Travel duration is 7h 50m
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TGV Lyria6h 0m016:10MilanPorta Garibaldi Train Station22:10LyonPart-Dieu Train Station0EconomyA Train from TGV Lyria goes from Porta Garibaldi Train Station, Milan (Italy) at 28/06/2026 16:10:00 to Part-Dieu Train Station, Lyon (France) arriving at 28/06/2026 22:10:00. 50 Economy ticket for £82 per person are available. Travel duration is 6h 0m
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TGV Lyria6h 0m012:10MilanPorta Garibaldi Train Station18:10LyonPart-Dieu Train Station0EconomyA Train from TGV Lyria goes from Porta Garibaldi Train Station, Milan (Italy) at 28/06/2026 12:10:00 to Part-Dieu Train Station, Lyon (France) arriving at 28/06/2026 18:10:00. 50 Economy ticket for £87 per person are available. Travel duration is 6h 0m
Cheapest Buses Sunday
Cheapest Flights Sunday
Cheapest Trains Sunday
What are the fastest trips from Milan to Lyon?
You can get to Lyon from Milan in just 4h 0m with a Flight from Vueling Airlines. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
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Skyscanner5h 45m006:55Bergamo AirportBergamo Airport12:40Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Skyscanner goes from Bergamo Airport, Bergamo Airport (Italy) at 22/06/2026 06:55:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 22/06/2026 12:40:00. 50 Economy ticket for £55 per person are available. Travel duration is 5h 45m
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EasyJet Airline6h 55m007:00Milan Linate AirportMilan Linate Airport13:55Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from EasyJet Airline goes from Milan Linate Airport, Milan Linate Airport (Italy) at 22/06/2026 07:00:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 22/06/2026 13:55:00. 50 Economy ticket for £59 per person are available. Travel duration is 6h 55m
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Air Dolomiti10h 45m006:20Milan Malpensa AirportMilan Malpensa Airport17:05Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Air Dolomiti goes from Milan Malpensa Airport, Milan Malpensa Airport (Italy) at 22/06/2026 06:20:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 22/06/2026 17:05:00. 50 Economy ticket for £122 per person are available. Travel duration is 10h 45m
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Itabus6h 35m014:55MilanLampugnano Bus Station21:30LyonPerrache Bus Stop0EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 22/06/2026 14:55:00 to Perrache Bus Stop, Lyon (France) arriving at 22/06/2026 21:30:00. 50 Economy ticket for £14 per person are available. Travel duration is 6h 35m
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Itabus6h 35m017:50MilanLampugnano Bus Station00:25LyonPerrache Bus Stop0EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 22/06/2026 17:50:00 to Perrache Bus Stop, Lyon (France) arriving at 23/06/2026 00:25:00. 50 Economy ticket for £14 per person are available. Travel duration is 6h 35m
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BlaBlaCar Bus6h 50m016:00MilanLampugnano Bus Station22:50LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Lampugnano Bus Station, Milan (Italy) at 22/06/2026 16:00:00 to Perrache Train Station, Lyon (France) arriving at 22/06/2026 22:50:00. 50 Economy ticket for £30 per person are available. Travel duration is 6h 50m
Fastest Flights Monday
Fastest Buses Monday
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Ryanair6h 15m015:00Bergamo AirportBergamo Airport21:15Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Ryanair goes from Bergamo Airport, Bergamo Airport (Italy) at 23/06/2026 15:00:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 23/06/2026 21:15:00. 50 Economy ticket for £63 per person are available. Travel duration is 6h 15m
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LC Perú7h 30m010:45Milan Malpensa AirportMilan Malpensa Airport18:15Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from LC Perú goes from Milan Malpensa Airport, Milan Malpensa Airport (Italy) at 23/06/2026 10:45:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 23/06/2026 18:15:00. 50 Economy ticket for £54 per person are available. Travel duration is 7h 30m
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Skyscanner9h 15m006:45Milan Malpensa AirportMilan Malpensa Airport16:00Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Skyscanner goes from Milan Malpensa Airport, Milan Malpensa Airport (Italy) at 23/06/2026 06:45:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 23/06/2026 16:00:00. 50 Economy ticket for £33 per person are available. Travel duration is 9h 15m
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Itabus6h 35m006:20MilanLampugnano Bus Station12:55LyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 23/06/2026 06:20:00 to Perrache Bus Stop, Lyon (France) arriving at 23/06/2026 12:55:00. 50 Premium Economy ticket for £13 per person are available. Travel duration is 6h 35m
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Itabus6h 35m014:55MilanLampugnano Bus Station21:30LyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 23/06/2026 14:55:00 to Perrache Bus Stop, Lyon (France) arriving at 23/06/2026 21:30:00. 50 Premium Economy ticket for £13 per person are available. Travel duration is 6h 35m
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FlixBus6h 35m018:00MilanLampugnano Bus Station00:35LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 23/06/2026 18:00:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 24/06/2026 00:35:00. 50 Economy ticket for £25 per person are available. Travel duration is 6h 35m
Fastest Flights Tuesday
Fastest Buses Tuesday
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Vueling Airlines5h 40m018:25Milan Malpensa AirportMilan Malpensa Airport00:05Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Vueling Airlines goes from Milan Malpensa Airport, Milan Malpensa Airport (Italy) at 24/06/2026 18:25:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 25/06/2026 00:05:00. 50 Economy ticket for £103 per person are available. Travel duration is 5h 40m
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Air Dolomiti6h 0m006:20Milan Malpensa AirportMilan Malpensa Airport12:20Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Air Dolomiti goes from Milan Malpensa Airport, Milan Malpensa Airport (Italy) at 24/06/2026 06:20:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 24/06/2026 12:20:00. 50 Economy ticket for £166 per person are available. Travel duration is 6h 0m
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EasyJet Airline9h 15m023:20Milan Malpensa AirportMilan Malpensa Airport08:35Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from EasyJet Airline goes from Milan Malpensa Airport, Milan Malpensa Airport (Italy) at 24/06/2026 23:20:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 25/06/2026 08:35:00. 50 Economy ticket for £77 per person are available. Travel duration is 9h 15m
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BlaBlaCar Bus6h 20m020:00MilanLampugnano Bus Station02:20LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Lampugnano Bus Station, Milan (Italy) at 24/06/2026 20:00:00 to Perrache Train Station, Lyon (France) arriving at 25/06/2026 02:20:00. 50 Economy ticket for £23 per person are available. Travel duration is 6h 20m
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Itabus6h 35m006:20MilanLampugnano Bus Station12:55LyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 24/06/2026 06:20:00 to Perrache Bus Stop, Lyon (France) arriving at 24/06/2026 12:55:00. 50 Premium Economy ticket for £13 per person are available. Travel duration is 6h 35m
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BlaBlaCar Bus6h 55m016:00MilanLampugnano Bus Station22:55LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Lampugnano Bus Station, Milan (Italy) at 24/06/2026 16:00:00 to Perrache Train Station, Lyon (France) arriving at 24/06/2026 22:55:00. 50 Economy ticket for £23 per person are available. Travel duration is 6h 55m
Fastest Flights Wednesday
Fastest Buses Wednesday
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BlaBlaCar5h 1m022:30Milan03:30Lyon0EconomyA Car from BlaBlaCar goes from , Milan (Italy) at 25/06/2026 22:30:00 to , Lyon (France) arriving at 26/06/2026 03:30:00. 50 Economy ticket for £25 per person are available. Travel duration is 5h 1m
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TGV Lyria6h 0m016:10MilanPorta Garibaldi Train Station22:10LyonPart-Dieu Train Station0EconomyA Train from TGV Lyria goes from Porta Garibaldi Train Station, Milan (Italy) at 25/06/2026 16:10:00 to Part-Dieu Train Station, Lyon (France) arriving at 25/06/2026 22:10:00. 50 Economy ticket for £86 per person are available. Travel duration is 6h 0m
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FlixBus6h 20m021:35MilanLampugnano Bus Station03:55LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 25/06/2026 21:35:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 26/06/2026 03:55:00. 50 Economy ticket for £27 per person are available. Travel duration is 6h 20m
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Itabus6h 35m014:55MilanLampugnano Bus Station21:30LyonPerrache Bus Stop0EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 25/06/2026 14:55:00 to Perrache Bus Stop, Lyon (France) arriving at 25/06/2026 21:30:00. 50 Economy ticket for £12 per person are available. Travel duration is 6h 35m
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Itabus6h 35m006:20MilanLampugnano Bus Station12:55LyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 25/06/2026 06:20:00 to Perrache Bus Stop, Lyon (France) arriving at 25/06/2026 12:55:00. 50 Premium Economy ticket for £13 per person are available. Travel duration is 6h 35m
Fastest Carpool Thursday
Fastest Trains Thursday
Fastest Buses Thursday
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Vueling Airlines4h 0m013:25Milan Malpensa AirportMilan Malpensa Airport17:25Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Vueling Airlines goes from Milan Malpensa Airport, Milan Malpensa Airport (Italy) at 26/06/2026 13:25:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 26/06/2026 17:25:00. 50 Economy ticket for £161 per person are available. Travel duration is 4h 0m
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Skyscanner4h 40m019:10Bergamo AirportBergamo Airport23:50Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Skyscanner goes from Bergamo Airport, Bergamo Airport (Italy) at 26/06/2026 19:10:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 26/06/2026 23:50:00. 50 Economy ticket for £124 per person are available. Travel duration is 4h 40m
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EasyJet Airline6h 10m017:40Milan Malpensa AirportMilan Malpensa Airport23:50Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from EasyJet Airline goes from Milan Malpensa Airport, Milan Malpensa Airport (Italy) at 26/06/2026 17:40:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 26/06/2026 23:50:00. 50 Economy ticket for £105 per person are available. Travel duration is 6h 10m
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Itabus6h 35m006:20MilanLampugnano Bus Station12:55LyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 26/06/2026 06:20:00 to Perrache Bus Stop, Lyon (France) arriving at 26/06/2026 12:55:00. 50 Premium Economy ticket for £13 per person are available. Travel duration is 6h 35m
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BlaBlaCar Bus6h 45m010:20MilanLampugnano Bus Station17:05LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Lampugnano Bus Station, Milan (Italy) at 26/06/2026 10:20:00 to Perrache Train Station, Lyon (France) arriving at 26/06/2026 17:05:00. 50 Economy ticket for £28 per person are available. Travel duration is 6h 45m
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FlixBus7h 10m009:15MilanLampugnano Bus Station16:25LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 26/06/2026 09:15:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 26/06/2026 16:25:00. 50 Economy ticket for £28 per person are available. Travel duration is 7h 10m
Fastest Flights Friday
Fastest Buses Friday
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FlixBus6h 15m005:45MilanLampugnano Bus Station12:00LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 27/06/2026 05:45:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 27/06/2026 12:00:00. 50 Economy ticket for £28 per person are available. Travel duration is 6h 15m
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Itabus6h 35m006:20MilanLampugnano Bus Station12:55LyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 27/06/2026 06:20:00 to Perrache Bus Stop, Lyon (France) arriving at 27/06/2026 12:55:00. 50 Premium Economy ticket for £17 per person are available. Travel duration is 6h 35m
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Itabus6h 35m014:55MilanLampugnano Bus Station21:30LyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 27/06/2026 14:55:00 to Perrache Bus Stop, Lyon (France) arriving at 27/06/2026 21:30:00. 50 Premium Economy ticket for £17 per person are available. Travel duration is 6h 35m
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LC Perú7h 45m018:15Milan Malpensa AirportMilan Malpensa Airport02:00Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from LC Perú goes from Milan Malpensa Airport, Milan Malpensa Airport (Italy) at 27/06/2026 18:15:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 28/06/2026 02:00:00. 50 Economy ticket for £100 per person are available. Travel duration is 7h 45m
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Nouvelair11h 5m022:05Milan Malpensa AirportMilan Malpensa Airport09:10Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Nouvelair goes from Milan Malpensa Airport, Milan Malpensa Airport (Italy) at 27/06/2026 22:05:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 28/06/2026 09:10:00. 50 Economy ticket for £162 per person are available. Travel duration is 11h 5m
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Vueling Airlines11h 40m011:10Milan Malpensa AirportMilan Malpensa Airport22:50Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Vueling Airlines goes from Milan Malpensa Airport, Milan Malpensa Airport (Italy) at 27/06/2026 11:10:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 27/06/2026 22:50:00. 50 Economy ticket for £118 per person are available. Travel duration is 11h 40m
Fastest Buses Saturday
Fastest Flights Saturday
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TGV Lyria6h 0m016:10MilanPorta Garibaldi Train Station22:10LyonPart-Dieu Train Station0EconomyA Train from TGV Lyria goes from Porta Garibaldi Train Station, Milan (Italy) at 28/06/2026 16:10:00 to Part-Dieu Train Station, Lyon (France) arriving at 28/06/2026 22:10:00. 50 Economy ticket for £82 per person are available. Travel duration is 6h 0m
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TGV Lyria6h 0m012:10MilanPorta Garibaldi Train Station18:10LyonPart-Dieu Train Station0EconomyA Train from TGV Lyria goes from Porta Garibaldi Train Station, Milan (Italy) at 28/06/2026 12:10:00 to Part-Dieu Train Station, Lyon (France) arriving at 28/06/2026 18:10:00. 50 Economy ticket for £87 per person are available. Travel duration is 6h 0m
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Skyscanner6h 20m019:05Bergamo AirportBergamo Airport01:25Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Skyscanner goes from Bergamo Airport, Bergamo Airport (Italy) at 28/06/2026 19:05:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 29/06/2026 01:25:00. 50 Economy ticket for £107 per person are available. Travel duration is 6h 20m
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EasyJet Airline7h 50m006:00Milan Malpensa AirportMilan Malpensa Airport13:50Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from EasyJet Airline goes from Milan Malpensa Airport, Milan Malpensa Airport (Italy) at 28/06/2026 06:00:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 28/06/2026 13:50:00. 50 Economy ticket for £104 per person are available. Travel duration is 7h 50m
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Ryanair12h 20m022:50Bergamo AirportBergamo Airport11:10Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Ryanair goes from Bergamo Airport, Bergamo Airport (Italy) at 28/06/2026 22:50:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 29/06/2026 11:10:00. 50 Economy ticket for £49 per person are available. Travel duration is 12h 20m
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Itabus6h 35m006:20MilanLampugnano Bus Station12:55LyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 28/06/2026 06:20:00 to Perrache Bus Stop, Lyon (France) arriving at 28/06/2026 12:55:00. 50 Premium Economy ticket for £13 per person are available. Travel duration is 6h 35m
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BlaBlaCar Bus6h 45m010:20MilanLampugnano Bus Station17:05LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Lampugnano Bus Station, Milan (Italy) at 28/06/2026 10:20:00 to Perrache Train Station, Lyon (France) arriving at 28/06/2026 17:05:00. 50 Economy ticket for £28 per person are available. Travel duration is 6h 45m
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Union Ivkoni8h 15m006:45MilanLampugnano Bus Station15:00LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from Union Ivkoni goes from Lampugnano Bus Station, Milan (Italy) at 28/06/2026 06:45:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 28/06/2026 15:00:00. 50 Economy ticket for £23 per person are available. Travel duration is 8h 15m
Fastest Trains Sunday
Fastest Flights Sunday
Fastest Buses Sunday
Here you will find all operators and timetables for a
Bus from Milan to Lyon
What are the most popular stations in Milan and Lyon?
In Milan, you will usually depart from Central Station - Piazza Luigi di Savoia, Lampugnano Bus Station or Cadorna Train Station, while in Lyon you will be arriving at Part-Dieu Train Station, Perrache Train Station or Perrache Bus Stop, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Lyon from Milan? With 9 connections between 7 Flight, Carpool, Train and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Milan and Lyon, you can pay as low as £12 with a Bus from Itabus.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Vueling Airlines: you will get to Lyon in just 4h 0m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Milan and Lyon are Itabus, BlaBlaCar Bus and EasyJet Airline, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Milan and Lyon is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Corsico or to Caluire-et-Cuire, and look at flights from Bergamo Airport, and landing at Lyons St. Exupery Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Milan to Lyon?
The most popular companies between Milan and Lyon, are Itabus, BlaBlaCar Bus and EasyJet Airline. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: Itabus, BlaBlaCar Bus, FlixBus and 1 more.
Train companies: TGV Lyria
Airlines: EasyJet Airline, Vueling Airlines, LC Perú and 7 more.
All you need to know when you travel from Milan to Lyon
Check all information on comfort and services on all modes of transports from Milan to Lyon. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Milan to Lyon
How can I reach Lyon from Milan?
Every day, there are on average 9 connections between Flight, Carpool, Train and Bus, with which you can get to Lyon from Milan.
How far is Lyon from Milan?
The distance between Milan and Lyon is 339.9 km.
What is the most ecofriendly mode of transport between Milan and Lyon?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 9 kgs of CO2, a train 12 kgs, a car 58 kgs, and a flight 84 kgs.
What is the cheapest mode of transport from Milan to Lyon?
You can get to Lyon with just £12 by taking a Bus from Itabus.
What is the fastest way to get from Milan to Lyon?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Lyon in just 4h 0m with a Flight from Vueling Airlines.
More routes to Milan and to Lyon
Looking for more options? Here you can see the most popular routes to Milan and to Lyon. Simply click on a connection, and you’ll find all the details about the route!
