What is the best way to travel from Brussels to Prague?
Looking for a trip? Check and compare all the available Buses and Flights to Prague from Brussels. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 3 available companies to find your perfect trip!
What is the cheapest way to reach Prague from Brussels?
You can reach Prague with just £34 by taking a Bus from BlaBlaCar Bus, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
-
FlixBus15h 10m021:30BrusselsNorth Station12:40PragueÚAN Florenc0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 21/03/2026 21:30:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 22/03/2026 12:40:00. 50 Economy ticket for £50 per person are available. Travel duration is 15h 10m
-
FlixBus17h 40m022:30BrusselsMidi Bus Station16:10PragueČerný Most0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 21/03/2026 22:30:00 to Černý Most, Prague (Czech Republic) arriving at 22/03/2026 16:10:00. 50 Economy ticket for £50 per person are available. Travel duration is 17h 40m
-
FlixBus13h 35m010:30BrusselsNorth Station00:05PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 21/03/2026 10:30:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 22/03/2026 00:05:00. 50 Economy ticket for £51 per person are available. Travel duration is 13h 35m
-
FlixBus13h 55m010:30BrusselsNorth Station00:25PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 21/03/2026 10:30:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 22/03/2026 00:25:00. 50 Economy ticket for £51 per person are available. Travel duration is 13h 55m
-
FlixBus16h 30m021:30BrusselsNorth Station14:00PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 21/03/2026 21:30:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 22/03/2026 14:00:00. 50 Economy ticket for £53 per person are available. Travel duration is 16h 30m
Cheapest Buses Saturday
-
FlixBus13h 55m010:30BrusselsNorth Station00:25PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 22/03/2026 10:30:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 23/03/2026 00:25:00. 50 Economy ticket for £47 per person are available. Travel duration is 13h 55m
-
FlixBus13h 35m010:30BrusselsNorth Station00:05PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 22/03/2026 10:30:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 23/03/2026 00:05:00. 50 Economy ticket for £47 per person are available. Travel duration is 13h 35m
-
FlixBus15h 0m022:30BrusselsMidi Bus Station13:30PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 22/03/2026 22:30:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 23/03/2026 13:30:00. 50 Economy ticket for £49 per person are available. Travel duration is 15h 0m
-
FlixBus12h 50m009:30BrusselsNorth Station22:20PragueÚAN Florenc0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 22/03/2026 09:30:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 22/03/2026 22:20:00. 50 Economy ticket for £54 per person are available. Travel duration is 12h 50m
-
FlixBus15h 55m010:55BrusselsNorth Station02:50PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 22/03/2026 10:55:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 23/03/2026 02:50:00. 50 Economy ticket for £56 per person are available. Travel duration is 15h 55m
-
Smartwings11h 35m019:55Brussels AirportBrussels Airport07:30Prague AirportPrague Airport - T1/20EconomyA Flight from Smartwings goes from Brussels Airport, Brussels Airport (Belgium) at 22/03/2026 19:55:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 23/03/2026 07:30:00. 50 Economy ticket for £49 per person are available. Travel duration is 11h 35m
-
Smartwings1h 25m019:30Brussels AirportBrussels Airport20:55Prague AirportPrague Airport - T1/20EconomyA Flight from Smartwings goes from Brussels Airport, Brussels Airport (Belgium) at 22/03/2026 19:30:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 22/03/2026 20:55:00. 50 Economy ticket for £62 per person are available. Travel duration is 1h 25m
-
Smartwings1h 25m019:30Brussels AirportBrussels Airport20:55Prague AirportPrague Airport0EconomyA Flight from Smartwings goes from Brussels Airport, Brussels Airport (Belgium) at 22/03/2026 19:30:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 22/03/2026 20:55:00. 50 Economy ticket for £64 per person are available. Travel duration is 1h 25m
-
Brussels Airlines1h 25m016:40Brussels AirportBrussels Airport18:05Prague AirportPrague Airport0EconomyA Flight from Brussels Airlines goes from Brussels Airport, Brussels Airport (Belgium) at 22/03/2026 16:40:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 22/03/2026 18:05:00. 50 Economy ticket for £81 per person are available. Travel duration is 1h 25m
-
Brussels Airlines1h 25m020:45Brussels AirportBrussels Airport22:10Prague AirportPrague Airport0EconomyA Flight from Brussels Airlines goes from Brussels Airport, Brussels Airport (Belgium) at 22/03/2026 20:45:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 22/03/2026 22:10:00. 50 Economy ticket for £81 per person are available. Travel duration is 1h 25m
Cheapest Buses Sunday
Cheapest Flights Sunday
-
FlixBus13h 35m010:30BrusselsNorth Station00:05PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 23/03/2026 10:30:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 24/03/2026 00:05:00. 50 Economy ticket for £38 per person are available. Travel duration is 13h 35m
-
FlixBus13h 55m010:30BrusselsNorth Station00:25PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 23/03/2026 10:30:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 24/03/2026 00:25:00. 50 Economy ticket for £38 per person are available. Travel duration is 13h 55m
-
FlixBus14h 40m016:15BrusselsMidi Bus Station06:55PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 23/03/2026 16:15:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 24/03/2026 06:55:00. 50 Economy ticket for £40 per person are available. Travel duration is 14h 40m
-
European Sleeper15h 29m019:22BrusselsMidi Bus Station10:51PragueWilsonova Coach Station0EconomyA Bus from European Sleeper goes from Midi Bus Station, Brussels (Belgium) at 23/03/2026 19:22:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 24/03/2026 10:51:00. 50 Economy ticket for £263 per person are available. Travel duration is 15h 29m
-
Ryanair1h 30m012:50Brussels South Charleroi AirportBrussels South Charleroi Airport14:20Prague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 23/03/2026 12:50:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 23/03/2026 14:20:00. 50 Economy ticket for £39 per person are available. Travel duration is 1h 30m
-
Smartwings1h 25m019:30Brussels AirportBrussels Airport20:55Prague AirportPrague Airport - T1/20EconomyA Flight from Smartwings goes from Brussels Airport, Brussels Airport (Belgium) at 23/03/2026 19:30:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 23/03/2026 20:55:00. 50 Economy ticket for £59 per person are available. Travel duration is 1h 25m
-
Smartwings1h 25m019:30Brussels AirportBrussels Airport20:55Prague AirportPrague Airport0EconomyA Flight from Smartwings goes from Brussels Airport, Brussels Airport (Belgium) at 23/03/2026 19:30:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 23/03/2026 20:55:00. 50 Economy ticket for £64 per person are available. Travel duration is 1h 25m
-
Brussels Airlines1h 25m016:30Brussels AirportBrussels Airport17:55Prague AirportPrague Airport - T1/20EconomyA Flight from Brussels Airlines goes from Brussels Airport, Brussels Airport (Belgium) at 23/03/2026 16:30:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 23/03/2026 17:55:00. 50 Economy ticket for £121 per person are available. Travel duration is 1h 25m
Cheapest Buses Monday
Cheapest Flights Monday
-
FlixBus12h 50m009:30BrusselsNorth Station22:20PragueÚAN Florenc0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 24/03/2026 09:30:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 24/03/2026 22:20:00. 50 Economy ticket for £36 per person are available. Travel duration is 12h 50m
-
FlixBus13h 55m010:30BrusselsNorth Station00:25PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 24/03/2026 10:30:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 25/03/2026 00:25:00. 50 Economy ticket for £36 per person are available. Travel duration is 13h 55m
-
FlixBus13h 35m010:30BrusselsNorth Station00:05PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 24/03/2026 10:30:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 25/03/2026 00:05:00. 50 Economy ticket for £36 per person are available. Travel duration is 13h 35m
-
FlixBus14h 40m016:15BrusselsMidi Bus Station06:55PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 24/03/2026 16:15:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 25/03/2026 06:55:00. 50 Economy ticket for £38 per person are available. Travel duration is 14h 40m
-
FlixBus17h 20m021:00BrusselsNorth Station14:20PragueÚAN Florenc0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 24/03/2026 21:00:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 25/03/2026 14:20:00. 50 Economy ticket for £43 per person are available. Travel duration is 17h 20m
Cheapest Buses Tuesday
-
FlixBus12h 50m009:30BrusselsNorth Station22:20PragueÚAN Florenc0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 25/03/2026 09:30:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 25/03/2026 22:20:00. 50 Economy ticket for £39 per person are available. Travel duration is 12h 50m
-
FlixBus14h 50m018:30BrusselsNorth Station09:20PragueÚAN Florenc0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 25/03/2026 18:30:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 26/03/2026 09:20:00. 50 Economy ticket for £43 per person are available. Travel duration is 14h 50m
-
FlixBus15h 55m007:00BrusselsNorth Station22:55PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 25/03/2026 07:00:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 25/03/2026 22:55:00. 50 Economy ticket for £44 per person are available. Travel duration is 15h 55m
-
European Sleeper17h 8m019:22BrusselsMidi Bus Station12:30PragueWilsonova Coach Station0EconomyA Bus from European Sleeper goes from Midi Bus Station, Brussels (Belgium) at 25/03/2026 19:22:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 26/03/2026 12:30:00. 50 Economy ticket for £834 per person are available. Travel duration is 17h 8m
Cheapest Buses Wednesday
-
FlixBus12h 50m009:30BrusselsNorth Station22:20PragueÚAN Florenc0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 26/03/2026 09:30:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 26/03/2026 22:20:00. 50 Economy ticket for £44 per person are available. Travel duration is 12h 50m
-
FlixBus15h 10m021:30BrusselsNorth Station12:40PragueÚAN Florenc0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 26/03/2026 21:30:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 27/03/2026 12:40:00. 50 Economy ticket for £57 per person are available. Travel duration is 15h 10m
-
FlixBus14h 40m016:15BrusselsMidi Bus Station06:55PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 26/03/2026 16:15:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 27/03/2026 06:55:00. 50 Economy ticket for £59 per person are available. Travel duration is 14h 40m
-
FlixBus18h 30m015:40BrusselsHeysel10:10PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Heysel, Brussels (Belgium) at 26/03/2026 15:40:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 27/03/2026 10:10:00. 50 Economy ticket for £60 per person are available. Travel duration is 18h 30m
-
FlixBus21h 25m004:15Brussels AirportBrussels Airport01:40PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Brussels Airport, Brussels Airport (Belgium) at 26/03/2026 04:15:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 27/03/2026 01:40:00. 50 Economy ticket for £60 per person are available. Travel duration is 21h 25m
-
Smartwings1h 25m019:30Brussels AirportBrussels Airport20:55Prague AirportPrague Airport - T1/20EconomyA Flight from Smartwings goes from Brussels Airport, Brussels Airport (Belgium) at 26/03/2026 19:30:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 26/03/2026 20:55:00. 50 Economy ticket for £58 per person are available. Travel duration is 1h 25m
-
Smartwings1h 25m008:55Brussels AirportBrussels Airport10:20Prague AirportPrague Airport - T1/20EconomyA Flight from Smartwings goes from Brussels Airport, Brussels Airport (Belgium) at 26/03/2026 08:55:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 26/03/2026 10:20:00. 50 Economy ticket for £72 per person are available. Travel duration is 1h 25m
-
Brussels Airlines1h 25m020:45Brussels AirportBrussels Airport22:10Prague AirportPrague Airport - T1/20EconomyA Flight from Brussels Airlines goes from Brussels Airport, Brussels Airport (Belgium) at 26/03/2026 20:45:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 26/03/2026 22:10:00. 50 Economy ticket for £115 per person are available. Travel duration is 1h 25m
-
Brussels Airlines1h 25m016:30Brussels AirportBrussels Airport17:55Prague AirportPrague Airport - T1/20EconomyA Flight from Brussels Airlines goes from Brussels Airport, Brussels Airport (Belgium) at 26/03/2026 16:30:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 26/03/2026 17:55:00. 50 Economy ticket for £122 per person are available. Travel duration is 1h 25m
-
Brussels Airlines1h 25m009:25Brussels AirportBrussels Airport10:50Prague AirportPrague Airport - T1/20EconomyA Flight from Brussels Airlines goes from Brussels Airport, Brussels Airport (Belgium) at 26/03/2026 09:25:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 26/03/2026 10:50:00. 50 Economy ticket for £547 per person are available. Travel duration is 1h 25m
Cheapest Buses Thursday
Cheapest Flights Thursday
-
BlaBlaCar Bus13h 35m020:10BrusselsMidi Bus Station09:45PragueÚAN Florenc0EconomyA Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 27/03/2026 20:10:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 28/03/2026 09:45:00. 50 Economy ticket for £34 per person are available. Travel duration is 13h 35m
-
FlixBus13h 55m010:30BrusselsNorth Station00:25PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 27/03/2026 10:30:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 28/03/2026 00:25:00. 50 Economy ticket for £41 per person are available. Travel duration is 13h 55m
-
FlixBus13h 35m010:30BrusselsNorth Station00:05PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 27/03/2026 10:30:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 28/03/2026 00:05:00. 50 Economy ticket for £41 per person are available. Travel duration is 13h 35m
-
European Sleeper15h 29m019:22BrusselsMidi Bus Station10:51PragueWilsonova Coach Station0EconomyA Bus from European Sleeper goes from Midi Bus Station, Brussels (Belgium) at 27/03/2026 19:22:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 28/03/2026 10:51:00. 50 Economy ticket for £115 per person are available. Travel duration is 15h 29m
-
Ryanair15h 30m017:05Brussels South Charleroi AirportBrussels South Charleroi Airport08:35Prague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 27/03/2026 17:05:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 28/03/2026 08:35:00. 50 Economy ticket for £60 per person are available. Travel duration is 15h 30m
-
LC Perú12h 20m009:45Brussels South Charleroi AirportBrussels South Charleroi Airport22:05Prague AirportPrague Airport - T1/20EconomyA Flight from LC Perú goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 27/03/2026 09:45:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 27/03/2026 22:05:00. 50 Economy ticket for £94 per person are available. Travel duration is 12h 20m
-
Buzz1h 30m020:20Brussels South Charleroi AirportBrussels South Charleroi Airport21:50Prague AirportPrague Airport - T1/20EconomyA Flight from Buzz goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 27/03/2026 20:20:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 27/03/2026 21:50:00. 50 Economy ticket for £96 per person are available. Travel duration is 1h 30m
-
Smartwings1h 25m019:30Brussels AirportBrussels Airport20:55Prague AirportPrague Airport - T1/20EconomyA Flight from Smartwings goes from Brussels Airport, Brussels Airport (Belgium) at 27/03/2026 19:30:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 27/03/2026 20:55:00. 50 Economy ticket for £104 per person are available. Travel duration is 1h 25m
-
Wizz Air7h 5m009:30Brussels South Charleroi AirportBrussels South Charleroi Airport16:35Prague AirportPrague Airport - T1/20EconomyA Flight from Wizz Air goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 27/03/2026 09:30:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 27/03/2026 16:35:00. 50 Economy ticket for £115 per person are available. Travel duration is 7h 5m
Cheapest Buses Friday
Cheapest Flights Friday
What are the fastest trips from Brussels to Prague?
You can get to Prague from Brussels in just 1h 25m with a Flight from Smartwings. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
-
FlixBus13h 35m010:30BrusselsNorth Station00:05PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 21/03/2026 10:30:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 22/03/2026 00:05:00. 50 Economy ticket for £51 per person are available. Travel duration is 13h 35m
-
FlixBus13h 55m010:30BrusselsNorth Station00:25PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 21/03/2026 10:30:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 22/03/2026 00:25:00. 50 Economy ticket for £51 per person are available. Travel duration is 13h 55m
-
FlixBus15h 10m021:30BrusselsNorth Station12:40PragueÚAN Florenc0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 21/03/2026 21:30:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 22/03/2026 12:40:00. 50 Economy ticket for £50 per person are available. Travel duration is 15h 10m
-
FlixBus16h 30m021:30BrusselsNorth Station14:00PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 21/03/2026 21:30:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 22/03/2026 14:00:00. 50 Economy ticket for £53 per person are available. Travel duration is 16h 30m
-
FlixBus17h 40m022:30BrusselsMidi Bus Station16:10PragueČerný Most0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 21/03/2026 22:30:00 to Černý Most, Prague (Czech Republic) arriving at 22/03/2026 16:10:00. 50 Economy ticket for £50 per person are available. Travel duration is 17h 40m
Fastest Buses Saturday
-
Smartwings1h 25m019:30Brussels AirportBrussels Airport20:55Prague AirportPrague Airport - T1/20EconomyA Flight from Smartwings goes from Brussels Airport, Brussels Airport (Belgium) at 22/03/2026 19:30:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 22/03/2026 20:55:00. 50 Economy ticket for £62 per person are available. Travel duration is 1h 25m
-
Smartwings1h 25m019:30Brussels AirportBrussels Airport20:55Prague AirportPrague Airport0EconomyA Flight from Smartwings goes from Brussels Airport, Brussels Airport (Belgium) at 22/03/2026 19:30:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 22/03/2026 20:55:00. 50 Economy ticket for £64 per person are available. Travel duration is 1h 25m
-
Brussels Airlines1h 25m016:40Brussels AirportBrussels Airport18:05Prague AirportPrague Airport0EconomyA Flight from Brussels Airlines goes from Brussels Airport, Brussels Airport (Belgium) at 22/03/2026 16:40:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 22/03/2026 18:05:00. 50 Economy ticket for £81 per person are available. Travel duration is 1h 25m
-
Brussels Airlines1h 25m020:45Brussels AirportBrussels Airport22:10Prague AirportPrague Airport0EconomyA Flight from Brussels Airlines goes from Brussels Airport, Brussels Airport (Belgium) at 22/03/2026 20:45:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 22/03/2026 22:10:00. 50 Economy ticket for £81 per person are available. Travel duration is 1h 25m
-
Smartwings11h 35m019:55Brussels AirportBrussels Airport07:30Prague AirportPrague Airport - T1/20EconomyA Flight from Smartwings goes from Brussels Airport, Brussels Airport (Belgium) at 22/03/2026 19:55:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 23/03/2026 07:30:00. 50 Economy ticket for £49 per person are available. Travel duration is 11h 35m
-
FlixBus12h 50m009:30BrusselsNorth Station22:20PragueÚAN Florenc0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 22/03/2026 09:30:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 22/03/2026 22:20:00. 50 Economy ticket for £54 per person are available. Travel duration is 12h 50m
-
FlixBus13h 35m010:30BrusselsNorth Station00:05PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 22/03/2026 10:30:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 23/03/2026 00:05:00. 50 Economy ticket for £47 per person are available. Travel duration is 13h 35m
-
FlixBus13h 55m010:30BrusselsNorth Station00:25PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 22/03/2026 10:30:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 23/03/2026 00:25:00. 50 Economy ticket for £47 per person are available. Travel duration is 13h 55m
-
FlixBus15h 0m022:30BrusselsMidi Bus Station13:30PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 22/03/2026 22:30:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 23/03/2026 13:30:00. 50 Economy ticket for £49 per person are available. Travel duration is 15h 0m
-
FlixBus15h 55m010:55BrusselsNorth Station02:50PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 22/03/2026 10:55:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 23/03/2026 02:50:00. 50 Economy ticket for £56 per person are available. Travel duration is 15h 55m
Fastest Flights Sunday
Fastest Buses Sunday
-
Smartwings1h 25m019:30Brussels AirportBrussels Airport20:55Prague AirportPrague Airport - T1/20EconomyA Flight from Smartwings goes from Brussels Airport, Brussels Airport (Belgium) at 23/03/2026 19:30:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 23/03/2026 20:55:00. 50 Economy ticket for £59 per person are available. Travel duration is 1h 25m
-
Smartwings1h 25m019:30Brussels AirportBrussels Airport20:55Prague AirportPrague Airport0EconomyA Flight from Smartwings goes from Brussels Airport, Brussels Airport (Belgium) at 23/03/2026 19:30:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 23/03/2026 20:55:00. 50 Economy ticket for £64 per person are available. Travel duration is 1h 25m
-
Brussels Airlines1h 25m016:30Brussels AirportBrussels Airport17:55Prague AirportPrague Airport - T1/20EconomyA Flight from Brussels Airlines goes from Brussels Airport, Brussels Airport (Belgium) at 23/03/2026 16:30:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 23/03/2026 17:55:00. 50 Economy ticket for £121 per person are available. Travel duration is 1h 25m
-
Ryanair1h 30m012:50Brussels South Charleroi AirportBrussels South Charleroi Airport14:20Prague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 23/03/2026 12:50:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 23/03/2026 14:20:00. 50 Economy ticket for £39 per person are available. Travel duration is 1h 30m
-
FlixBus13h 35m010:30BrusselsNorth Station00:05PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 23/03/2026 10:30:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 24/03/2026 00:05:00. 50 Economy ticket for £38 per person are available. Travel duration is 13h 35m
-
FlixBus13h 55m010:30BrusselsNorth Station00:25PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 23/03/2026 10:30:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 24/03/2026 00:25:00. 50 Economy ticket for £38 per person are available. Travel duration is 13h 55m
-
FlixBus14h 40m016:15BrusselsMidi Bus Station06:55PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 23/03/2026 16:15:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 24/03/2026 06:55:00. 50 Economy ticket for £40 per person are available. Travel duration is 14h 40m
-
European Sleeper15h 29m019:22BrusselsMidi Bus Station10:51PragueWilsonova Coach Station0EconomyA Bus from European Sleeper goes from Midi Bus Station, Brussels (Belgium) at 23/03/2026 19:22:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 24/03/2026 10:51:00. 50 Economy ticket for £263 per person are available. Travel duration is 15h 29m
Fastest Flights Monday
Fastest Buses Monday
-
FlixBus12h 50m009:30BrusselsNorth Station22:20PragueÚAN Florenc0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 24/03/2026 09:30:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 24/03/2026 22:20:00. 50 Economy ticket for £36 per person are available. Travel duration is 12h 50m
-
FlixBus13h 35m010:30BrusselsNorth Station00:05PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 24/03/2026 10:30:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 25/03/2026 00:05:00. 50 Economy ticket for £36 per person are available. Travel duration is 13h 35m
-
FlixBus13h 55m010:30BrusselsNorth Station00:25PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 24/03/2026 10:30:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 25/03/2026 00:25:00. 50 Economy ticket for £36 per person are available. Travel duration is 13h 55m
-
FlixBus14h 40m016:15BrusselsMidi Bus Station06:55PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 24/03/2026 16:15:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 25/03/2026 06:55:00. 50 Economy ticket for £38 per person are available. Travel duration is 14h 40m
-
FlixBus17h 20m021:00BrusselsNorth Station14:20PragueÚAN Florenc0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 24/03/2026 21:00:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 25/03/2026 14:20:00. 50 Economy ticket for £43 per person are available. Travel duration is 17h 20m
Fastest Buses Tuesday
-
FlixBus12h 50m009:30BrusselsNorth Station22:20PragueÚAN Florenc0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 25/03/2026 09:30:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 25/03/2026 22:20:00. 50 Economy ticket for £39 per person are available. Travel duration is 12h 50m
-
FlixBus14h 50m018:30BrusselsNorth Station09:20PragueÚAN Florenc0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 25/03/2026 18:30:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 26/03/2026 09:20:00. 50 Economy ticket for £43 per person are available. Travel duration is 14h 50m
-
FlixBus15h 55m007:00BrusselsNorth Station22:55PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 25/03/2026 07:00:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 25/03/2026 22:55:00. 50 Economy ticket for £44 per person are available. Travel duration is 15h 55m
-
European Sleeper17h 8m019:22BrusselsMidi Bus Station12:30PragueWilsonova Coach Station0EconomyA Bus from European Sleeper goes from Midi Bus Station, Brussels (Belgium) at 25/03/2026 19:22:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 26/03/2026 12:30:00. 50 Economy ticket for £834 per person are available. Travel duration is 17h 8m
Fastest Buses Wednesday
-
Smartwings1h 25m019:30Brussels AirportBrussels Airport20:55Prague AirportPrague Airport - T1/20EconomyA Flight from Smartwings goes from Brussels Airport, Brussels Airport (Belgium) at 26/03/2026 19:30:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 26/03/2026 20:55:00. 50 Economy ticket for £58 per person are available. Travel duration is 1h 25m
-
Smartwings1h 25m008:55Brussels AirportBrussels Airport10:20Prague AirportPrague Airport - T1/20EconomyA Flight from Smartwings goes from Brussels Airport, Brussels Airport (Belgium) at 26/03/2026 08:55:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 26/03/2026 10:20:00. 50 Economy ticket for £72 per person are available. Travel duration is 1h 25m
-
Brussels Airlines1h 25m020:45Brussels AirportBrussels Airport22:10Prague AirportPrague Airport - T1/20EconomyA Flight from Brussels Airlines goes from Brussels Airport, Brussels Airport (Belgium) at 26/03/2026 20:45:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 26/03/2026 22:10:00. 50 Economy ticket for £115 per person are available. Travel duration is 1h 25m
-
Brussels Airlines1h 25m016:30Brussels AirportBrussels Airport17:55Prague AirportPrague Airport - T1/20EconomyA Flight from Brussels Airlines goes from Brussels Airport, Brussels Airport (Belgium) at 26/03/2026 16:30:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 26/03/2026 17:55:00. 50 Economy ticket for £122 per person are available. Travel duration is 1h 25m
-
Brussels Airlines1h 25m009:25Brussels AirportBrussels Airport10:50Prague AirportPrague Airport - T1/20EconomyA Flight from Brussels Airlines goes from Brussels Airport, Brussels Airport (Belgium) at 26/03/2026 09:25:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 26/03/2026 10:50:00. 50 Economy ticket for £547 per person are available. Travel duration is 1h 25m
-
FlixBus12h 50m009:30BrusselsNorth Station22:20PragueÚAN Florenc0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 26/03/2026 09:30:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 26/03/2026 22:20:00. 50 Economy ticket for £44 per person are available. Travel duration is 12h 50m
-
FlixBus14h 40m016:15BrusselsMidi Bus Station06:55PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 26/03/2026 16:15:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 27/03/2026 06:55:00. 50 Economy ticket for £59 per person are available. Travel duration is 14h 40m
-
FlixBus15h 10m021:30BrusselsNorth Station12:40PragueÚAN Florenc0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 26/03/2026 21:30:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 27/03/2026 12:40:00. 50 Economy ticket for £57 per person are available. Travel duration is 15h 10m
-
FlixBus18h 30m015:40BrusselsHeysel10:10PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Heysel, Brussels (Belgium) at 26/03/2026 15:40:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 27/03/2026 10:10:00. 50 Economy ticket for £60 per person are available. Travel duration is 18h 30m
-
FlixBus21h 25m004:15Brussels AirportBrussels Airport01:40PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Brussels Airport, Brussels Airport (Belgium) at 26/03/2026 04:15:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 27/03/2026 01:40:00. 50 Economy ticket for £60 per person are available. Travel duration is 21h 25m
Fastest Flights Thursday
Fastest Buses Thursday
-
Smartwings1h 25m019:30Brussels AirportBrussels Airport20:55Prague AirportPrague Airport - T1/20EconomyA Flight from Smartwings goes from Brussels Airport, Brussels Airport (Belgium) at 27/03/2026 19:30:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 27/03/2026 20:55:00. 50 Economy ticket for £104 per person are available. Travel duration is 1h 25m
-
Buzz1h 30m020:20Brussels South Charleroi AirportBrussels South Charleroi Airport21:50Prague AirportPrague Airport - T1/20EconomyA Flight from Buzz goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 27/03/2026 20:20:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 27/03/2026 21:50:00. 50 Economy ticket for £96 per person are available. Travel duration is 1h 30m
-
Wizz Air7h 5m009:30Brussels South Charleroi AirportBrussels South Charleroi Airport16:35Prague AirportPrague Airport - T1/20EconomyA Flight from Wizz Air goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 27/03/2026 09:30:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 27/03/2026 16:35:00. 50 Economy ticket for £115 per person are available. Travel duration is 7h 5m
-
LC Perú12h 20m009:45Brussels South Charleroi AirportBrussels South Charleroi Airport22:05Prague AirportPrague Airport - T1/20EconomyA Flight from LC Perú goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 27/03/2026 09:45:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 27/03/2026 22:05:00. 50 Economy ticket for £94 per person are available. Travel duration is 12h 20m
-
Ryanair15h 30m017:05Brussels South Charleroi AirportBrussels South Charleroi Airport08:35Prague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 27/03/2026 17:05:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 28/03/2026 08:35:00. 50 Economy ticket for £60 per person are available. Travel duration is 15h 30m
-
BlaBlaCar Bus13h 35m020:10BrusselsMidi Bus Station09:45PragueÚAN Florenc0EconomyA Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 27/03/2026 20:10:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 28/03/2026 09:45:00. 50 Economy ticket for £34 per person are available. Travel duration is 13h 35m
-
FlixBus13h 35m010:30BrusselsNorth Station00:05PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 27/03/2026 10:30:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 28/03/2026 00:05:00. 50 Economy ticket for £41 per person are available. Travel duration is 13h 35m
-
FlixBus13h 55m010:30BrusselsNorth Station00:25PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 27/03/2026 10:30:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 28/03/2026 00:25:00. 50 Economy ticket for £41 per person are available. Travel duration is 13h 55m
-
European Sleeper15h 29m019:22BrusselsMidi Bus Station10:51PragueWilsonova Coach Station0EconomyA Bus from European Sleeper goes from Midi Bus Station, Brussels (Belgium) at 27/03/2026 19:22:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 28/03/2026 10:51:00. 50 Economy ticket for £115 per person are available. Travel duration is 15h 29m
Fastest Flights Friday
Fastest Buses Friday
Here you will find all operators and timetables for a
Bus from Brussels to Prague
What are the most popular stations in Brussels and Prague?
In Brussels, you will usually depart from Midi Bus Station, North Station or Gare Centrale, while in Prague you will be arriving at Wilsonova Coach Station, ÚAN Florenc or Černý Most, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Prague from Brussels? With 7 connections between 3 Flight and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Brussels and Prague, you can pay as low as £34 with a Bus from BlaBlaCar Bus.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Smartwings: you will get to Prague in just 1h 25m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Brussels and Prague are FlixBus, Smartwings and Brussels Airlines, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Brussels and Prague is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Saint-Gilles or to Horoměřice, and look at flights from Brussels South Charleroi Airport, and landing at Prague Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Brussels to Prague?
The most popular companies between Brussels and Prague, are FlixBus, Smartwings and Brussels Airlines. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: FlixBus, European Sleeper and BlaBlaCar Bus
Airlines: Smartwings, Brussels Airlines, Ryanair and 3 more.
All you need to know when you travel from Brussels to Prague
Check all information on comfort and services on all modes of transports from Brussels to Prague. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Brussels to Prague
How can I reach Prague from Brussels?
Every day, there are on average 7 connections between Flight and Bus, with which you can get to Prague from Brussels.
How far is Prague from Brussels?
The distance between Brussels and Prague is 718.5 km.
What is the most ecofriendly mode of transport between Brussels and Prague?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 19 kgs of CO2, a train 25 kgs, a car 122 kgs, and a flight 177 kgs.
What is the cheapest mode of transport from Brussels to Prague?
You can get to Prague with just £34 by taking a Bus from BlaBlaCar Bus.
What is the fastest way to get from Brussels to Prague?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Prague in just 1h 25m with a Flight from Smartwings.
More routes to Brussels and to Prague
Looking for more options? Here you can see the most popular routes to Brussels and to Prague. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Brussels
- Amsterdam to Brussels
- Barcelona to Brussels
- Basel to Brussels
- Berlin to Brussels
- Birmingham to Brussels
- Bologna to Brussels
- Bordeaux to Brussels
- Brussels South Charleroi Airport to Brussels
- Carcassonne to Brussels
- Cologne/Bonn Airport to Brussels
- Edinburgh to Brussels
- Lille to Brussels
- Lisbon to Brussels
- London to Brussels
- Lucerne to Brussels
- Lyon to Brussels
- Milan to Brussels
- Newcastle upon Tyne to Brussels
- Nottingham to Brussels
- Paris to Brussels
- Salzburg to Brussels
- The Hague to Brussels
- Vienna to Brussels
- Zurich to Brussels
- Trips to Prague
- Berlin to Prague
- Bologna to Prague
- Bratislava to Prague
- Brno to Prague
- Česká Lípa to Prague
- Český Krumlov to Prague
- Florence to Prague
- Hamburg to Prague
- Hanover to Prague
- Humpolec to Prague
- Jihlava to Prague
- Katowice to Prague
- Kornwestheim to Prague
- Kosice to Prague
- Linz to Prague
- Milan to Prague
- Munich Airport to Prague
- Paris to Prague
- Pilsen to Prague
- Presov to Prague
- Teplice to Prague
- Warsaw Chopin Airport to Prague
- Warsaw to Prague
- Wroclaw to Prague
