How to get from Brussels to Prague

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What is the best way to travel from Brussels to Prague?

Looking for a trip? Check and compare all the available Buses and Flights to Prague from Brussels. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 2 available companies to find your perfect trip!
Flight is the cheapest and fastest way on this route
Transport type
Travel time
Cheapest price
Average price
Daily departures
Bus
12h 50m
£58
£91
62
Flight
1h 25m
£57
£108
115

What is the cheapest way to reach Prague from Brussels?

You can reach Prague with just £57 by taking a Flight from Smartwings, but there are many more cheap offers: we have selected the best ones for you for the next few days here.

Friday
from £62
Saturday
from £80
Sunday
from £58
Monday
from £65
Tuesday
from £64
Wednesday
from £58
Thursday
from £57

    Cheapest Flights Friday

  • Buzz
    1h 30m
    0
    20:20
    Brussels South Charleroi Airport
    Brussels South Charleroi Airport
    21:50
    Prague Airport
    Prague Airport - T1/2
    0
    Buzz
    Economy
    from £62
  • Ryanair
    1h 25m
    0
    09:55
    Brussels Airport
    Brussels Airport
    11:20
    Prague Airport
    Prague Airport - T1/2
    0
    Ryanair
    Economy
    from £63
  • Smartwings
    1h 25m
    0
    19:30
    Brussels Airport
    Brussels Airport
    20:55
    Prague Airport
    Prague Airport - T1/2
    0
    Smartwings
    Economy
    from £94
  • Austrian Airlines
    6h 10m
    0
    09:50
    Brussels Airport
    Brussels Airport
    16:00
    Prague Airport
    Prague Airport - T1/2
    0
    Austrian Airlines
    Economy
    from £114
  • Brussels Airlines
    3h 55m
    0
    10:00
    Brussels Airport
    Brussels Airport
    13:55
    Prague Airport
    Prague Airport - T1/2
    0
    Brussels Airlines
    Economy
    from £130
  • Cheapest Buses Friday

  • FlixBus
    13h 55m
    0
    10:30
    Brussels
    North Station
    00:25
    Prague
    Wilsonova Coach Station
    0
    FlixBus
    Economy
    £74
  • FlixBus
    13h 35m
    0
    10:30
    Brussels
    North Station
    00:05
    Prague
    Na Knížecí Station
    0
    FlixBus
    Economy
    £74
  • FlixBus
    17h 40m
    0
    13:00
    Brussels
    North Station
    06:40
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    £99
  • European Sleeper
    15h 57m
    0
    19:22
    Brussels
    Midi Bus Station
    11:19
    Prague
    Wilsonova Coach Station
    0
    European Sleeper
    Economy
    £464

    Cheapest Buses Saturday

  • FlixBus
    18h 45m
    0
    21:25
    Brussels
    North Station
    16:10
    Prague
    Černý Most
    0
    FlixBus
    Economy
    £80
  • FlixBus
    15h 0m
    0
    22:10
    Brussels
    Midi Bus Station
    13:10
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    £88
  • FlixBus
    13h 35m
    0
    10:30
    Brussels
    North Station
    00:05
    Prague
    Na Knížecí Station
    0
    FlixBus
    Economy
    £88
  • FlixBus
    15h 10m
    0
    17:30
    Brussels
    North Station
    08:40
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    £90
  • FlixBus
    19h 35m
    0
    22:00
    Brussels
    North Station
    17:35
    Prague
    Hradčanská
    0
    FlixBus
    Economy
    £90
  • Cheapest Flights Saturday

  • Skyscanner
    16h 10m
    0
    17:30
    Brussels South Charleroi Airport
    Brussels South Charleroi Airport
    09:40
    Prague Airport
    Prague Airport - T1/2
    0
    Skyscanner
    Economy
    from £92
  • Ryanair
    24h 10m
    0
    21:10
    Brussels South Charleroi Airport
    Brussels South Charleroi Airport
    21:20
    Prague Airport
    Prague Airport - T1/2
    0
    Ryanair
    Economy
    from £98
  • Lauda Europe
    27h 15m
    0
    20:35
    Brussels South Charleroi Airport
    Brussels South Charleroi Airport
    23:50
    Prague Airport
    Prague Airport - T1/2
    0
    Lauda Europe
    Economy
    from £133
  • LOT Polish Airlines / Polskie Linie Lotnicze
    13h 10m
    0
    19:40
    Brussels Airport
    Brussels Airport
    08:50
    Prague Airport
    Prague Airport - T1/2
    0
    LOT Polish Airlines / Polskie Linie Lotnicze
    Economy
    from £180
  • Smartwings
    1h 25m
    0
    08:55
    Brussels Airport
    Brussels Airport
    10:20
    Prague Airport
    Prague Airport - T1/2
    0
    Smartwings
    Economy
    from £188

    Cheapest Flights Sunday

  • Ryanair
    1h 25m
    0
    20:30
    Brussels Airport
    Brussels Airport
    21:55
    Prague Airport
    Prague Airport - T1/2
    0
    Ryanair
    Economy
    from £58
  • Smartwings
    1h 25m
    0
    19:30
    Brussels Airport
    Brussels Airport
    20:55
    Prague Airport
    Prague Airport - T1/2
    0
    Smartwings
    Economy
    from £61
  • Brussels Airlines
    1h 25m
    0
    20:45
    Brussels Airport
    Brussels Airport
    22:10
    Prague Airport
    Prague Airport - T1/2
    0
    Brussels Airlines
    Economy
    from £80
  • Skyscanner
    12h 15m
    0
    09:00
    Brussels South Charleroi Airport
    Brussels South Charleroi Airport
    21:15
    Prague Airport
    Prague Airport - T1/2
    0
    Skyscanner
    Economy
    from £88
  • LOT Polish Airlines / Polskie Linie Lotnicze
    16h 30m
    0
    19:40
    Brussels Airport
    Brussels Airport
    12:10
    Prague Airport
    Prague Airport - T1/2
    0
    LOT Polish Airlines / Polskie Linie Lotnicze
    Economy
    from £134
  • Cheapest Buses Sunday

  • FlixBus
    13h 35m
    0
    10:30
    Brussels
    North Station
    00:05
    Prague
    Na Knížecí Station
    0
    FlixBus
    Economy
    £74
  • FlixBus
    13h 55m
    0
    10:30
    Brussels
    North Station
    00:25
    Prague
    Wilsonova Coach Station
    0
    FlixBus
    Economy
    £74
  • FlixBus
    18h 45m
    0
    21:25
    Brussels
    North Station
    16:10
    Prague
    Černý Most
    0
    FlixBus
    Economy
    £74
  • FlixBus
    19h 15m
    0
    16:15
    Brussels
    Midi Bus Station
    11:30
    Prague
    Wilsonova Coach Station
    0
    FlixBus
    Economy
    £84
  • FlixBus
    12h 50m
    0
    09:30
    Brussels
    North Station
    22:20
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    £86

    Cheapest Flights Monday

  • Pegasus Airlines
    1h 25m
    0
    19:30
    Brussels Airport
    Brussels Airport
    20:55
    Prague Airport
    Prague Airport - T1/2
    0
    Pegasus Airlines
    Economy
    from £65
  • Smartwings
    1h 25m
    0
    19:30
    Brussels Airport
    Brussels Airport
    20:55
    Prague Airport
    Prague Airport - T1/2
    0
    Smartwings
    Economy
    from £93
  • Ryanair
    10h 40m
    0
    07:35
    Brussels South Charleroi Airport
    Brussels South Charleroi Airport
    18:15
    Prague Airport
    Prague Airport - T1/2
    0
    Ryanair
    Economy
    from £95
  • Air Malta
    23h 25m
    0
    20:25
    Brussels Airport
    Brussels Airport
    19:50
    Prague Airport
    Prague Airport - T1/2
    0
    Air Malta
    Economy
    from £125
  • EasyJet Airline
    7h 5m
    0
    09:25
    Brussels Airport
    Brussels Airport
    16:30
    Prague Airport
    Prague Airport - T1/2
    0
    EasyJet Airline
    Economy
    from £143
  • Cheapest Buses Monday

  • FlixBus
    18h 45m
    0
    21:25
    Brussels
    North Station
    16:10
    Prague
    Černý Most
    0
    FlixBus
    Economy
    £66
  • FlixBus
    13h 35m
    0
    10:30
    Brussels
    North Station
    00:05
    Prague
    Na Knížecí Station
    0
    FlixBus
    Economy
    £69
  • FlixBus
    17h 55m
    0
    03:15
    Brussels
    Midi Bus Station
    21:10
    Prague
    Na Knížecí Station
    0
    FlixBus
    Economy
    £70
  • European Sleeper
    15h 57m
    0
    19:22
    Brussels
    Midi Bus Station
    11:19
    Prague
    Wilsonova Coach Station
    0
    European Sleeper
    Economy
    £149

    Cheapest Buses Tuesday

  • FlixBus
    13h 35m
    0
    10:30
    Brussels
    North Station
    00:05
    Prague
    Na Knížecí Station
    0
    FlixBus
    Economy
    £64
  • FlixBus
    13h 55m
    0
    10:30
    Brussels
    North Station
    00:25
    Prague
    Wilsonova Coach Station
    0
    FlixBus
    Economy
    £64
  • FlixBus
    15h 10m
    0
    17:30
    Brussels
    North Station
    08:40
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    £69
  • FlixBus
    16h 40m
    0
    16:15
    Brussels
    Midi Bus Station
    08:55
    Prague
    Na Knížecí Station
    0
    FlixBus
    Economy
    £70
  • FlixBus
    15h 25m
    0
    17:30
    Brussels
    North Station
    08:55
    Prague
    Na Knížecí Station
    0
    FlixBus
    Economy
    £70
  • Cheapest Flights Tuesday

  • Smartwings
    1h 25m
    0
    19:30
    Brussels Airport
    Brussels Airport
    20:55
    Prague Airport
    Prague Airport - T1/2
    0
    Smartwings
    Economy
    from £72
  • Buzz
    1h 30m
    0
    19:25
    Brussels South Charleroi Airport
    Brussels South Charleroi Airport
    20:55
    Prague Airport
    Prague Airport - T1/2
    0
    Buzz
    Economy
    from £79
  • Wizz Air
    11h 5m
    0
    09:45
    Brussels South Charleroi Airport
    Brussels South Charleroi Airport
    20:50
    Prague Airport
    Prague Airport - T1/2
    0
    Wizz Air
    Economy
    from £101
  • Ryanair
    15h 30m
    0
    06:25
    Brussels South Charleroi Airport
    Brussels South Charleroi Airport
    21:55
    Prague Airport
    Prague Airport - T1/2
    0
    Ryanair
    Economy
    from £115
  • Skyscanner
    5h 10m
    0
    09:20
    Brussels South Charleroi Airport
    Brussels South Charleroi Airport
    14:30
    Prague Airport
    Prague Airport - T1/2
    0
    Skyscanner
    Economy
    from £136

    Cheapest Buses Wednesday

  • FlixBus
    14h 40m
    0
    16:15
    Brussels
    Midi Bus Station
    06:55
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    £58
  • FlixBus
    12h 50m
    0
    09:30
    Brussels
    North Station
    22:20
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    £60
  • FlixBus
    13h 55m
    0
    10:30
    Brussels
    North Station
    00:25
    Prague
    Wilsonova Coach Station
    0
    FlixBus
    Economy
    £60
  • European Sleeper
    15h 57m
    0
    19:22
    Brussels
    Midi Bus Station
    11:19
    Prague
    Wilsonova Coach Station
    0
    European Sleeper
    Economy
    £184

    Cheapest Flights Thursday

  • Smartwings
    1h 25m
    0
    08:55
    Brussels Airport
    Brussels Airport
    10:20
    Prague Airport
    Prague Airport - T1/2
    0
    Smartwings
    Economy
    from £57
  • LC Perú
    25h 5m
    0
    21:00
    Brussels South Charleroi Airport
    Brussels South Charleroi Airport
    22:05
    Prague Airport
    Prague Airport - T1/2
    0
    LC Perú
    Economy
    from £92
  • Wizz Air
    11h 35m
    0
    19:55
    Brussels South Charleroi Airport
    Brussels South Charleroi Airport
    07:30
    Prague Airport
    Prague Airport - T1/2
    0
    Wizz Air
    Economy
    from £149
  • SAS Scandinavian Airlines
    4h 0m
    0
    10:20
    Brussels Airport
    Brussels Airport
    14:20
    Prague Airport
    Prague Airport - T1/2
    0
    SAS Scandinavian Airlines
    Economy
    from £172
  • Brussels Airlines
    1h 25m
    0
    09:25
    Brussels Airport
    Brussels Airport
    10:50
    Prague Airport
    Prague Airport - T1/2
    0
    Brussels Airlines
    Economy
    from £174
  • Cheapest Buses Thursday

  • FlixBus
    14h 40m
    0
    16:15
    Brussels
    Midi Bus Station
    06:55
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    £61
  • FlixBus
    13h 55m
    0
    10:30
    Brussels
    North Station
    00:25
    Prague
    Wilsonova Coach Station
    0
    FlixBus
    Economy
    £61
  • FlixBus
    13h 35m
    0
    10:30
    Brussels
    North Station
    00:05
    Prague
    Na Knížecí Station
    0
    FlixBus
    Economy
    £61
  • FlixBus
    15h 0m
    0
    22:10
    Brussels
    Midi Bus Station
    13:10
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    £67
  • FlixBus
    18h 35m
    0
    16:15
    Brussels
    Midi Bus Station
    10:50
    Prague
    Wilsonova Coach Station
    0
    FlixBus
    Economy
    £78

What are the fastest trips from Brussels to Prague?

You can get to Prague from Brussels in just 1h 25m with a Flight from Ryanair. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.

Friday
from 1h 25m
Saturday
from 1h 25m
Sunday
from 1h 25m
Monday
from 1h 25m
Tuesday
from 1h 25m
Wednesday
from 12h 50m
Thursday
from 1h 25m

    Fastest Flights Friday

  • Ryanair
    1h 25m
    0
    09:55
    Brussels Airport
    Brussels Airport
    11:20
    Prague Airport
    Prague Airport - T1/2
    0
    Ryanair
    Economy
    from £63
  • Smartwings
    1h 25m
    0
    19:30
    Brussels Airport
    Brussels Airport
    20:55
    Prague Airport
    Prague Airport - T1/2
    0
    Smartwings
    Economy
    from £94
  • Buzz
    1h 30m
    0
    20:20
    Brussels South Charleroi Airport
    Brussels South Charleroi Airport
    21:50
    Prague Airport
    Prague Airport - T1/2
    0
    Buzz
    Economy
    from £62
  • Brussels Airlines
    3h 55m
    0
    10:00
    Brussels Airport
    Brussels Airport
    13:55
    Prague Airport
    Prague Airport - T1/2
    0
    Brussels Airlines
    Economy
    from £130
  • Austrian Airlines
    6h 10m
    0
    09:50
    Brussels Airport
    Brussels Airport
    16:00
    Prague Airport
    Prague Airport - T1/2
    0
    Austrian Airlines
    Economy
    from £114
  • Fastest Buses Friday

  • FlixBus
    13h 35m
    0
    10:30
    Brussels
    North Station
    00:05
    Prague
    Na Knížecí Station
    0
    FlixBus
    Economy
    £74
  • FlixBus
    13h 55m
    0
    10:30
    Brussels
    North Station
    00:25
    Prague
    Wilsonova Coach Station
    0
    FlixBus
    Economy
    £74
  • European Sleeper
    15h 57m
    0
    19:22
    Brussels
    Midi Bus Station
    11:19
    Prague
    Wilsonova Coach Station
    0
    European Sleeper
    Economy
    £464
  • FlixBus
    17h 40m
    0
    13:00
    Brussels
    North Station
    06:40
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    £99

    Fastest Flights Saturday

  • Smartwings
    1h 25m
    0
    08:55
    Brussels Airport
    Brussels Airport
    10:20
    Prague Airport
    Prague Airport - T1/2
    0
    Smartwings
    Economy
    from £188
  • LOT Polish Airlines / Polskie Linie Lotnicze
    13h 10m
    0
    19:40
    Brussels Airport
    Brussels Airport
    08:50
    Prague Airport
    Prague Airport - T1/2
    0
    LOT Polish Airlines / Polskie Linie Lotnicze
    Economy
    from £180
  • Skyscanner
    16h 10m
    0
    17:30
    Brussels South Charleroi Airport
    Brussels South Charleroi Airport
    09:40
    Prague Airport
    Prague Airport - T1/2
    0
    Skyscanner
    Economy
    from £92
  • Ryanair
    24h 10m
    0
    21:10
    Brussels South Charleroi Airport
    Brussels South Charleroi Airport
    21:20
    Prague Airport
    Prague Airport - T1/2
    0
    Ryanair
    Economy
    from £98
  • Lauda Europe
    27h 15m
    0
    20:35
    Brussels South Charleroi Airport
    Brussels South Charleroi Airport
    23:50
    Prague Airport
    Prague Airport - T1/2
    0
    Lauda Europe
    Economy
    from £133
  • Fastest Buses Saturday

  • FlixBus
    13h 35m
    0
    10:30
    Brussels
    North Station
    00:05
    Prague
    Na Knížecí Station
    0
    FlixBus
    Economy
    £88
  • FlixBus
    15h 0m
    0
    22:10
    Brussels
    Midi Bus Station
    13:10
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    £88
  • FlixBus
    15h 10m
    0
    17:30
    Brussels
    North Station
    08:40
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    £90
  • FlixBus
    18h 45m
    0
    21:25
    Brussels
    North Station
    16:10
    Prague
    Černý Most
    0
    FlixBus
    Economy
    £80
  • FlixBus
    19h 35m
    0
    22:00
    Brussels
    North Station
    17:35
    Prague
    Hradčanská
    0
    FlixBus
    Economy
    £90

    Fastest Flights Sunday

  • Ryanair
    1h 25m
    0
    20:30
    Brussels Airport
    Brussels Airport
    21:55
    Prague Airport
    Prague Airport - T1/2
    0
    Ryanair
    Economy
    from £58
  • Smartwings
    1h 25m
    0
    19:30
    Brussels Airport
    Brussels Airport
    20:55
    Prague Airport
    Prague Airport - T1/2
    0
    Smartwings
    Economy
    from £61
  • Brussels Airlines
    1h 25m
    0
    20:45
    Brussels Airport
    Brussels Airport
    22:10
    Prague Airport
    Prague Airport - T1/2
    0
    Brussels Airlines
    Economy
    from £80
  • Skyscanner
    12h 15m
    0
    09:00
    Brussels South Charleroi Airport
    Brussels South Charleroi Airport
    21:15
    Prague Airport
    Prague Airport - T1/2
    0
    Skyscanner
    Economy
    from £88
  • LOT Polish Airlines / Polskie Linie Lotnicze
    16h 30m
    0
    19:40
    Brussels Airport
    Brussels Airport
    12:10
    Prague Airport
    Prague Airport - T1/2
    0
    LOT Polish Airlines / Polskie Linie Lotnicze
    Economy
    from £134
  • Fastest Buses Sunday

  • FlixBus
    12h 50m
    0
    09:30
    Brussels
    North Station
    22:20
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    £86
  • FlixBus
    13h 35m
    0
    10:30
    Brussels
    North Station
    00:05
    Prague
    Na Knížecí Station
    0
    FlixBus
    Economy
    £74
  • FlixBus
    13h 55m
    0
    10:30
    Brussels
    North Station
    00:25
    Prague
    Wilsonova Coach Station
    0
    FlixBus
    Economy
    £74
  • FlixBus
    18h 45m
    0
    21:25
    Brussels
    North Station
    16:10
    Prague
    Černý Most
    0
    FlixBus
    Economy
    £74
  • FlixBus
    19h 15m
    0
    16:15
    Brussels
    Midi Bus Station
    11:30
    Prague
    Wilsonova Coach Station
    0
    FlixBus
    Economy
    £84

    Fastest Flights Monday

  • Pegasus Airlines
    1h 25m
    0
    19:30
    Brussels Airport
    Brussels Airport
    20:55
    Prague Airport
    Prague Airport - T1/2
    0
    Pegasus Airlines
    Economy
    from £65
  • Smartwings
    1h 25m
    0
    19:30
    Brussels Airport
    Brussels Airport
    20:55
    Prague Airport
    Prague Airport - T1/2
    0
    Smartwings
    Economy
    from £93
  • EasyJet Airline
    7h 5m
    0
    09:25
    Brussels Airport
    Brussels Airport
    16:30
    Prague Airport
    Prague Airport - T1/2
    0
    EasyJet Airline
    Economy
    from £143
  • Ryanair
    10h 40m
    0
    07:35
    Brussels South Charleroi Airport
    Brussels South Charleroi Airport
    18:15
    Prague Airport
    Prague Airport - T1/2
    0
    Ryanair
    Economy
    from £95
  • Air Malta
    23h 25m
    0
    20:25
    Brussels Airport
    Brussels Airport
    19:50
    Prague Airport
    Prague Airport - T1/2
    0
    Air Malta
    Economy
    from £125
  • Fastest Buses Monday

  • FlixBus
    13h 35m
    0
    10:30
    Brussels
    North Station
    00:05
    Prague
    Na Knížecí Station
    0
    FlixBus
    Economy
    £69
  • European Sleeper
    15h 57m
    0
    19:22
    Brussels
    Midi Bus Station
    11:19
    Prague
    Wilsonova Coach Station
    0
    European Sleeper
    Economy
    £149
  • FlixBus
    17h 55m
    0
    03:15
    Brussels
    Midi Bus Station
    21:10
    Prague
    Na Knížecí Station
    0
    FlixBus
    Economy
    £70
  • FlixBus
    18h 45m
    0
    21:25
    Brussels
    North Station
    16:10
    Prague
    Černý Most
    0
    FlixBus
    Economy
    £66

    Fastest Flights Tuesday

  • Smartwings
    1h 25m
    0
    19:30
    Brussels Airport
    Brussels Airport
    20:55
    Prague Airport
    Prague Airport - T1/2
    0
    Smartwings
    Economy
    from £72
  • Buzz
    1h 30m
    0
    19:25
    Brussels South Charleroi Airport
    Brussels South Charleroi Airport
    20:55
    Prague Airport
    Prague Airport - T1/2
    0
    Buzz
    Economy
    from £79
  • Skyscanner
    5h 10m
    0
    09:20
    Brussels South Charleroi Airport
    Brussels South Charleroi Airport
    14:30
    Prague Airport
    Prague Airport - T1/2
    0
    Skyscanner
    Economy
    from £136
  • Wizz Air
    11h 5m
    0
    09:45
    Brussels South Charleroi Airport
    Brussels South Charleroi Airport
    20:50
    Prague Airport
    Prague Airport - T1/2
    0
    Wizz Air
    Economy
    from £101
  • Ryanair
    15h 30m
    0
    06:25
    Brussels South Charleroi Airport
    Brussels South Charleroi Airport
    21:55
    Prague Airport
    Prague Airport - T1/2
    0
    Ryanair
    Economy
    from £115
  • Fastest Buses Tuesday

  • FlixBus
    13h 35m
    0
    10:30
    Brussels
    North Station
    00:05
    Prague
    Na Knížecí Station
    0
    FlixBus
    Economy
    £64
  • FlixBus
    13h 55m
    0
    10:30
    Brussels
    North Station
    00:25
    Prague
    Wilsonova Coach Station
    0
    FlixBus
    Economy
    £64
  • FlixBus
    15h 10m
    0
    17:30
    Brussels
    North Station
    08:40
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    £69
  • FlixBus
    15h 25m
    0
    17:30
    Brussels
    North Station
    08:55
    Prague
    Na Knížecí Station
    0
    FlixBus
    Economy
    £70
  • FlixBus
    16h 40m
    0
    16:15
    Brussels
    Midi Bus Station
    08:55
    Prague
    Na Knížecí Station
    0
    FlixBus
    Economy
    £70

    Fastest Buses Wednesday

  • FlixBus
    12h 50m
    0
    09:30
    Brussels
    North Station
    22:20
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    £60
  • FlixBus
    13h 55m
    0
    10:30
    Brussels
    North Station
    00:25
    Prague
    Wilsonova Coach Station
    0
    FlixBus
    Economy
    £60
  • FlixBus
    14h 40m
    0
    16:15
    Brussels
    Midi Bus Station
    06:55
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    £58
  • European Sleeper
    15h 57m
    0
    19:22
    Brussels
    Midi Bus Station
    11:19
    Prague
    Wilsonova Coach Station
    0
    European Sleeper
    Economy
    £184

    Fastest Flights Thursday

  • Smartwings
    1h 25m
    0
    08:55
    Brussels Airport
    Brussels Airport
    10:20
    Prague Airport
    Prague Airport - T1/2
    0
    Smartwings
    Economy
    from £57
  • Brussels Airlines
    1h 25m
    0
    09:25
    Brussels Airport
    Brussels Airport
    10:50
    Prague Airport
    Prague Airport - T1/2
    0
    Brussels Airlines
    Economy
    from £174
  • SAS Scandinavian Airlines
    4h 0m
    0
    10:20
    Brussels Airport
    Brussels Airport
    14:20
    Prague Airport
    Prague Airport - T1/2
    0
    SAS Scandinavian Airlines
    Economy
    from £172
  • Wizz Air
    11h 35m
    0
    19:55
    Brussels South Charleroi Airport
    Brussels South Charleroi Airport
    07:30
    Prague Airport
    Prague Airport - T1/2
    0
    Wizz Air
    Economy
    from £149
  • LC Perú
    25h 5m
    0
    21:00
    Brussels South Charleroi Airport
    Brussels South Charleroi Airport
    22:05
    Prague Airport
    Prague Airport - T1/2
    0
    LC Perú
    Economy
    from £92
  • Fastest Buses Thursday

  • FlixBus
    13h 35m
    0
    10:30
    Brussels
    North Station
    00:05
    Prague
    Na Knížecí Station
    0
    FlixBus
    Economy
    £61
  • FlixBus
    13h 55m
    0
    10:30
    Brussels
    North Station
    00:25
    Prague
    Wilsonova Coach Station
    0
    FlixBus
    Economy
    £61
  • FlixBus
    14h 40m
    0
    16:15
    Brussels
    Midi Bus Station
    06:55
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    £61
  • FlixBus
    15h 0m
    0
    22:10
    Brussels
    Midi Bus Station
    13:10
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    £67
  • FlixBus
    18h 35m
    0
    16:15
    Brussels
    Midi Bus Station
    10:50
    Prague
    Wilsonova Coach Station
    0
    FlixBus
    Economy
    £78
Here you will find all operators and timetables for a Bus from Brussels to Prague

What are the most popular stations in Brussels and Prague?

In Brussels, you will usually depart from Midi Bus Station, North Station or Gare Centrale, while in Prague you will be arriving at Wilsonova Coach Station, ÚAN Florenc or Černý Most, but there are many more stops to explore in both locations.

How do I decide? Some tips and tricks from our experience

Are you having trouble deciding on how to get to Prague from Brussels? With 8 connections between 2 Bus and Flight operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.

Look for the lowest price

Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Brussels and Prague, you can pay as low as £57 with a Flight from Smartwings.

Travel duration

Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Ryanair: you will get to Prague in just 1h 25m.

Comfort makes all the difference

You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Brussels and Prague are FlixBus, Smartwings and Ryanair, but be sure to check what they have to offer!

Save money with deals, and always compare

One last tip? Even if you live in Brussels and Prague is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Saint-Gilles or to Horoměřice, and look at flights from Brussels South Charleroi Airport, and landing at Prague Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!

Which companies offer a trip from Brussels to Prague?

The most popular companies between Brussels and Prague, are FlixBus, Smartwings and Ryanair. Be sure to check their seat class offers and the amenities that they provide.

Bus companies: FlixBus and European Sleeper

Airlines: Smartwings, Ryanair, Brussels Airlines and 11 more.

All you need to know when you travel from Brussels to Prague

Check all information on comfort and services on all modes of transports from Brussels to Prague. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.

FAQs about the trip from Brussels to Prague

How can I reach Prague from Brussels?

Every day, there are on average 8 connections between Bus and Flight, with which you can get to Prague from Brussels.

How far is Prague from Brussels?

The distance between Brussels and Prague is 718.5 km.

What is the most ecofriendly mode of transport between Brussels and Prague?

Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance. On this particular route, a bus will emit, per person, a total of 19 kgs of CO2, a train 25 kgs, a car 122 kgs, and a flight 177 kgs.

What is the cheapest mode of transport from Brussels to Prague?

You can get to Prague with just £57 by taking a Flight from Smartwings.

What is the fastest way to get from Brussels to Prague?

While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Prague in just 1h 25m with a Flight from Ryanair.

More routes to Brussels and to Prague

Looking for more options? Here you can see the most popular routes to Brussels and to Prague. Simply click on a connection, and you’ll find all the details about the route!

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