What is the best way to travel from Brussels to Prague?
Looking for a trip? Check and compare all the available Buses and Flights to Prague from Brussels. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 3 available companies to find your perfect trip!
What is the cheapest way to reach Prague from Brussels?
You can reach Prague with just £30 by taking a Flight from Ryanair, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
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FlixBus18h 35m022:55BrusselsNorth Station17:30PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 05/12/2025 22:55:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 06/12/2025 17:30:00. 50 Economy ticket for £52 per person are available. Travel duration is 18h 35m
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FlixBus19h 35m022:00BrusselsNorth Station17:35PragueHradčanská0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 05/12/2025 22:00:00 to Hradčanská, Prague (Czech Republic) arriving at 06/12/2025 17:35:00. 50 Economy ticket for £52 per person are available. Travel duration is 19h 35m
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FlixBus13h 35m010:30BrusselsNorth Station00:05PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 05/12/2025 10:30:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 06/12/2025 00:05:00. 50 Economy ticket for £53 per person are available. Travel duration is 13h 35m
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European Sleeper17h 23m019:22BrusselsMidi Bus Station12:45PragueWilsonova Coach Station0EconomyA Bus from European Sleeper goes from Midi Bus Station, Brussels (Belgium) at 05/12/2025 19:22:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 06/12/2025 12:45:00. 50 Economy ticket for £250 per person are available. Travel duration is 17h 23m
Cheapest Buses Friday
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FlixBus19h 15m016:15BrusselsMidi Bus Station11:30PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 06/12/2025 16:15:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 07/12/2025 11:30:00. 50 Economy ticket for £41 per person are available. Travel duration is 19h 15m
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FlixBus15h 15m021:25BrusselsNorth Station12:40PragueÚAN Florenc0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 06/12/2025 21:25:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 07/12/2025 12:40:00. 50 Economy ticket for £41 per person are available. Travel duration is 15h 15m
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FlixBus16h 5m010:55BrusselsNorth Station03:00PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 06/12/2025 10:55:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 07/12/2025 03:00:00. 50 Economy ticket for £41 per person are available. Travel duration is 16h 5m
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FlixBus19h 35m011:20BrusselsNorth Station06:55PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 06/12/2025 11:20:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 07/12/2025 06:55:00. 50 Economy ticket for £41 per person are available. Travel duration is 19h 35m
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FlixBus16h 35m021:25BrusselsNorth Station14:00PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 06/12/2025 21:25:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 07/12/2025 14:00:00. 50 Economy ticket for £41 per person are available. Travel duration is 16h 35m
Cheapest Buses Saturday
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Ryanair13h 30m007:50Brussels South Charleroi AirportBrussels South Charleroi Airport21:20Prague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 07/12/2025 07:50:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 07/12/2025 21:20:00. 50 Economy ticket for £43 per person are available. Travel duration is 13h 30m
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Smartwings1h 25m019:30Brussels AirportBrussels Airport20:55Prague AirportPrague Airport - T1/20EconomyA Flight from Smartwings goes from Brussels Airport, Brussels Airport (Belgium) at 07/12/2025 19:30:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 07/12/2025 20:55:00. 50 Economy ticket for £61 per person are available. Travel duration is 1h 25m
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Skyscanner26h 35m013:55Brussels South Charleroi AirportBrussels South Charleroi Airport16:30Prague AirportPrague Airport - T1/20EconomyA Flight from Skyscanner goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 07/12/2025 13:55:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 08/12/2025 16:30:00. 50 Economy ticket for £70 per person are available. Travel duration is 26h 35m
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LC Perú12h 15m009:55Brussels South Charleroi AirportBrussels South Charleroi Airport22:10Prague AirportPrague Airport - T1/20EconomyA Flight from LC Perú goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 07/12/2025 09:55:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 07/12/2025 22:10:00. 50 Economy ticket for £72 per person are available. Travel duration is 12h 15m
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Buzz16h 35m014:55Brussels South Charleroi AirportBrussels South Charleroi Airport07:30Prague AirportPrague Airport - T1/20EconomyA Flight from Buzz goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 07/12/2025 14:55:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 08/12/2025 07:30:00. 50 Economy ticket for £79 per person are available. Travel duration is 16h 35m
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FlixBus16h 5m010:55BrusselsNorth Station03:00PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 07/12/2025 10:55:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 08/12/2025 03:00:00. 50 Economy ticket for £52 per person are available. Travel duration is 16h 5m
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FlixBus18h 35m022:55BrusselsNorth Station17:30PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 07/12/2025 22:55:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 08/12/2025 17:30:00. 50 Economy ticket for £52 per person are available. Travel duration is 18h 35m
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FlixBus19h 35m022:00BrusselsNorth Station17:35PragueHradčanská0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 07/12/2025 22:00:00 to Hradčanská, Prague (Czech Republic) arriving at 08/12/2025 17:35:00. 50 Economy ticket for £52 per person are available. Travel duration is 19h 35m
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FlixBus17h 50m001:20BrusselsMidi Bus Station19:10PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 07/12/2025 01:20:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 07/12/2025 19:10:00. 50 Economy ticket for £56 per person are available. Travel duration is 17h 50m
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FlixBus18h 30m001:20BrusselsMidi Bus Station19:50PragueZličín0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 07/12/2025 01:20:00 to Zličín, Prague (Czech Republic) arriving at 07/12/2025 19:50:00. 50 Economy ticket for £57 per person are available. Travel duration is 18h 30m
Cheapest Flights Sunday
Cheapest Buses Sunday
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Ryanair1h 30m012:50Brussels South Charleroi AirportBrussels South Charleroi Airport14:20Prague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 08/12/2025 12:50:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 08/12/2025 14:20:00. 50 Economy ticket for £30 per person are available. Travel duration is 1h 30m
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Smartwings1h 25m008:55Brussels AirportBrussels Airport10:20Prague AirportPrague Airport - T1/20EconomyA Flight from Smartwings goes from Brussels Airport, Brussels Airport (Belgium) at 08/12/2025 08:55:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 08/12/2025 10:20:00. 50 Economy ticket for £61 per person are available. Travel duration is 1h 25m
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Wizz Air15h 50m016:30Brussels South Charleroi AirportBrussels South Charleroi Airport08:20Prague AirportPrague Airport - T1/20EconomyA Flight from Wizz Air goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 08/12/2025 16:30:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 09/12/2025 08:20:00. 50 Economy ticket for £68 per person are available. Travel duration is 15h 50m
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Buzz16h 20m016:00Brussels South Charleroi AirportBrussels South Charleroi Airport08:20Prague AirportPrague Airport - T1/20EconomyA Flight from Buzz goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 08/12/2025 16:00:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 09/12/2025 08:20:00. 50 Economy ticket for £70 per person are available. Travel duration is 16h 20m
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Pegasus Airlines15h 30m018:00Brussels South Charleroi AirportBrussels South Charleroi Airport09:30Prague AirportPrague Airport - T1/20EconomyA Flight from Pegasus Airlines goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 08/12/2025 18:00:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 09/12/2025 09:30:00. 50 Economy ticket for £108 per person are available. Travel duration is 15h 30m
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FlixBus16h 40m016:15BrusselsMidi Bus Station08:55PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 08/12/2025 16:15:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 09/12/2025 08:55:00. 50 Economy ticket for £38 per person are available. Travel duration is 16h 40m
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FlixBus16h 10m007:00BrusselsNorth Station23:10PragueÚAN Florenc0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 08/12/2025 07:00:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 08/12/2025 23:10:00. 50 Economy ticket for £38 per person are available. Travel duration is 16h 10m
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FlixBus15h 0m015:55BrusselsNorth Station06:55PragueÚAN Florenc0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 08/12/2025 15:55:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 09/12/2025 06:55:00. 50 Economy ticket for £38 per person are available. Travel duration is 15h 0m
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European Sleeper17h 23m019:22BrusselsMidi Bus Station12:45PragueWilsonova Coach Station0EconomyA Bus from European Sleeper goes from Midi Bus Station, Brussels (Belgium) at 08/12/2025 19:22:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 09/12/2025 12:45:00. 50 Economy ticket for £233 per person are available. Travel duration is 17h 23m
Cheapest Flights Monday
Cheapest Buses Monday
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FlixBus16h 40m016:15BrusselsMidi Bus Station08:55PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 09/12/2025 16:15:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 10/12/2025 08:55:00. 50 Economy ticket for £34 per person are available. Travel duration is 16h 40m
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FlixBus15h 10m017:30BrusselsNorth Station08:40PragueÚAN Florenc0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 09/12/2025 17:30:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 10/12/2025 08:40:00. 50 Economy ticket for £34 per person are available. Travel duration is 15h 10m
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FlixBus18h 35m022:55BrusselsNorth Station17:30PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 09/12/2025 22:55:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 10/12/2025 17:30:00. 50 Economy ticket for £34 per person are available. Travel duration is 18h 35m
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FlixBus15h 25m017:30BrusselsNorth Station08:55PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 09/12/2025 17:30:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 10/12/2025 08:55:00. 50 Economy ticket for £34 per person are available. Travel duration is 15h 25m
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FlixBus17h 50m001:20BrusselsMidi Bus Station19:10PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 09/12/2025 01:20:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 09/12/2025 19:10:00. 50 Economy ticket for £35 per person are available. Travel duration is 17h 50m
Cheapest Buses Tuesday
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FlixBus17h 50m016:15BrusselsMidi Bus Station10:05PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 10/12/2025 16:15:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 11/12/2025 10:05:00. 50 Economy ticket for £36 per person are available. Travel duration is 17h 50m
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FlixBus19h 15m016:15BrusselsMidi Bus Station11:30PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 10/12/2025 16:15:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 11/12/2025 11:30:00. 50 Economy ticket for £37 per person are available. Travel duration is 19h 15m
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FlixBus16h 35m017:30BrusselsNorth Station10:05PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 10/12/2025 17:30:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 11/12/2025 10:05:00. 50 Economy ticket for £37 per person are available. Travel duration is 16h 35m
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European Sleeper16h 33m019:22BrusselsMidi Bus Station11:55PragueWilsonova Coach Station0EconomyA Bus from European Sleeper goes from Midi Bus Station, Brussels (Belgium) at 10/12/2025 19:22:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 11/12/2025 11:55:00. 50 Economy ticket for £251 per person are available. Travel duration is 16h 33m
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Smartwings1h 25m008:55Brussels AirportBrussels Airport10:20Prague AirportPrague Airport - T1/20EconomyA Flight from Smartwings goes from Brussels Airport, Brussels Airport (Belgium) at 10/12/2025 08:55:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 10/12/2025 10:20:00. 50 Economy ticket for £61 per person are available. Travel duration is 1h 25m
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Buzz22h 25m008:35Brussels South Charleroi AirportBrussels South Charleroi Airport07:00Prague AirportPrague Airport - T1/20EconomyA Flight from Buzz goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 10/12/2025 08:35:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 11/12/2025 07:00:00. 50 Economy ticket for £64 per person are available. Travel duration is 22h 25m
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Skyscanner12h 0m009:10Brussels South Charleroi AirportBrussels South Charleroi Airport21:10Prague AirportPrague Airport - T1/20EconomyA Flight from Skyscanner goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 10/12/2025 09:10:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 10/12/2025 21:10:00. 50 Economy ticket for £73 per person are available. Travel duration is 12h 0m
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Ryanair25h 10m018:00Brussels South Charleroi AirportBrussels South Charleroi Airport19:10Prague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 10/12/2025 18:00:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 11/12/2025 19:10:00. 50 Economy ticket for £78 per person are available. Travel duration is 25h 10m
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Wizz Air5h 0m016:30Brussels South Charleroi AirportBrussels South Charleroi Airport21:30Prague AirportPrague Airport - T1/20EconomyA Flight from Wizz Air goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 10/12/2025 16:30:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 10/12/2025 21:30:00. 50 Economy ticket for £93 per person are available. Travel duration is 5h 0m
Cheapest Buses Wednesday
Cheapest Flights Wednesday
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FlixBus20h 50m021:25BrusselsNorth Station18:15PragueHolesovice0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 11/12/2025 21:25:00 to Holesovice, Prague (Czech Republic) arriving at 12/12/2025 18:15:00. 50 Economy ticket for £39 per person are available. Travel duration is 20h 50m
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FlixBus20h 55m006:20BrusselsNorth Station03:15PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 11/12/2025 06:20:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 12/12/2025 03:15:00. 50 Economy ticket for £40 per person are available. Travel duration is 20h 55m
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FlixBus18h 35m009:00BrusselsNorth Station03:35PragueÚAN Florenc0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 11/12/2025 09:00:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 12/12/2025 03:35:00. 50 Economy ticket for £40 per person are available. Travel duration is 18h 35m
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FlixBus18h 10m014:30BrusselsNorth Station08:40PragueÚAN Florenc0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 11/12/2025 14:30:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 12/12/2025 08:40:00. 50 Economy ticket for £43 per person are available. Travel duration is 18h 10m
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FlixBus19h 15m000:45BrusselsMidi Bus Station20:00PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 11/12/2025 00:45:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 11/12/2025 20:00:00. 50 Economy ticket for £45 per person are available. Travel duration is 19h 15m
Cheapest Buses Thursday
What are the fastest trips from Brussels to Prague?
You can get to Prague from Brussels in just 1h 25m with a Flight from Smartwings. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
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FlixBus13h 35m010:30BrusselsNorth Station00:05PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 05/12/2025 10:30:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 06/12/2025 00:05:00. 50 Economy ticket for £53 per person are available. Travel duration is 13h 35m
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European Sleeper17h 23m019:22BrusselsMidi Bus Station12:45PragueWilsonova Coach Station0EconomyA Bus from European Sleeper goes from Midi Bus Station, Brussels (Belgium) at 05/12/2025 19:22:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 06/12/2025 12:45:00. 50 Economy ticket for £250 per person are available. Travel duration is 17h 23m
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FlixBus18h 35m022:55BrusselsNorth Station17:30PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 05/12/2025 22:55:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 06/12/2025 17:30:00. 50 Economy ticket for £52 per person are available. Travel duration is 18h 35m
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FlixBus19h 35m022:00BrusselsNorth Station17:35PragueHradčanská0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 05/12/2025 22:00:00 to Hradčanská, Prague (Czech Republic) arriving at 06/12/2025 17:35:00. 50 Economy ticket for £52 per person are available. Travel duration is 19h 35m
Fastest Buses Friday
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FlixBus15h 15m021:25BrusselsNorth Station12:40PragueÚAN Florenc0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 06/12/2025 21:25:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 07/12/2025 12:40:00. 50 Economy ticket for £41 per person are available. Travel duration is 15h 15m
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FlixBus16h 5m010:55BrusselsNorth Station03:00PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 06/12/2025 10:55:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 07/12/2025 03:00:00. 50 Economy ticket for £41 per person are available. Travel duration is 16h 5m
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FlixBus16h 35m021:25BrusselsNorth Station14:00PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 06/12/2025 21:25:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 07/12/2025 14:00:00. 50 Economy ticket for £41 per person are available. Travel duration is 16h 35m
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FlixBus19h 15m016:15BrusselsMidi Bus Station11:30PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 06/12/2025 16:15:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 07/12/2025 11:30:00. 50 Economy ticket for £41 per person are available. Travel duration is 19h 15m
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FlixBus19h 35m011:20BrusselsNorth Station06:55PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 06/12/2025 11:20:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 07/12/2025 06:55:00. 50 Economy ticket for £41 per person are available. Travel duration is 19h 35m
Fastest Buses Saturday
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Smartwings1h 25m019:30Brussels AirportBrussels Airport20:55Prague AirportPrague Airport - T1/20EconomyA Flight from Smartwings goes from Brussels Airport, Brussels Airport (Belgium) at 07/12/2025 19:30:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 07/12/2025 20:55:00. 50 Economy ticket for £61 per person are available. Travel duration is 1h 25m
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LC Perú12h 15m009:55Brussels South Charleroi AirportBrussels South Charleroi Airport22:10Prague AirportPrague Airport - T1/20EconomyA Flight from LC Perú goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 07/12/2025 09:55:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 07/12/2025 22:10:00. 50 Economy ticket for £72 per person are available. Travel duration is 12h 15m
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Ryanair13h 30m007:50Brussels South Charleroi AirportBrussels South Charleroi Airport21:20Prague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 07/12/2025 07:50:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 07/12/2025 21:20:00. 50 Economy ticket for £43 per person are available. Travel duration is 13h 30m
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Buzz16h 35m014:55Brussels South Charleroi AirportBrussels South Charleroi Airport07:30Prague AirportPrague Airport - T1/20EconomyA Flight from Buzz goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 07/12/2025 14:55:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 08/12/2025 07:30:00. 50 Economy ticket for £79 per person are available. Travel duration is 16h 35m
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Skyscanner26h 35m013:55Brussels South Charleroi AirportBrussels South Charleroi Airport16:30Prague AirportPrague Airport - T1/20EconomyA Flight from Skyscanner goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 07/12/2025 13:55:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 08/12/2025 16:30:00. 50 Economy ticket for £70 per person are available. Travel duration is 26h 35m
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FlixBus16h 5m010:55BrusselsNorth Station03:00PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 07/12/2025 10:55:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 08/12/2025 03:00:00. 50 Economy ticket for £52 per person are available. Travel duration is 16h 5m
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FlixBus17h 50m001:20BrusselsMidi Bus Station19:10PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 07/12/2025 01:20:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 07/12/2025 19:10:00. 50 Economy ticket for £56 per person are available. Travel duration is 17h 50m
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FlixBus18h 30m001:20BrusselsMidi Bus Station19:50PragueZličín0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 07/12/2025 01:20:00 to Zličín, Prague (Czech Republic) arriving at 07/12/2025 19:50:00. 50 Economy ticket for £57 per person are available. Travel duration is 18h 30m
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FlixBus18h 35m022:55BrusselsNorth Station17:30PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 07/12/2025 22:55:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 08/12/2025 17:30:00. 50 Economy ticket for £52 per person are available. Travel duration is 18h 35m
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FlixBus19h 35m022:00BrusselsNorth Station17:35PragueHradčanská0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 07/12/2025 22:00:00 to Hradčanská, Prague (Czech Republic) arriving at 08/12/2025 17:35:00. 50 Economy ticket for £52 per person are available. Travel duration is 19h 35m
Fastest Flights Sunday
Fastest Buses Sunday
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Smartwings1h 25m008:55Brussels AirportBrussels Airport10:20Prague AirportPrague Airport - T1/20EconomyA Flight from Smartwings goes from Brussels Airport, Brussels Airport (Belgium) at 08/12/2025 08:55:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 08/12/2025 10:20:00. 50 Economy ticket for £61 per person are available. Travel duration is 1h 25m
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Ryanair1h 30m012:50Brussels South Charleroi AirportBrussels South Charleroi Airport14:20Prague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 08/12/2025 12:50:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 08/12/2025 14:20:00. 50 Economy ticket for £30 per person are available. Travel duration is 1h 30m
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Pegasus Airlines15h 30m018:00Brussels South Charleroi AirportBrussels South Charleroi Airport09:30Prague AirportPrague Airport - T1/20EconomyA Flight from Pegasus Airlines goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 08/12/2025 18:00:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 09/12/2025 09:30:00. 50 Economy ticket for £108 per person are available. Travel duration is 15h 30m
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Wizz Air15h 50m016:30Brussels South Charleroi AirportBrussels South Charleroi Airport08:20Prague AirportPrague Airport - T1/20EconomyA Flight from Wizz Air goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 08/12/2025 16:30:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 09/12/2025 08:20:00. 50 Economy ticket for £68 per person are available. Travel duration is 15h 50m
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Buzz16h 20m016:00Brussels South Charleroi AirportBrussels South Charleroi Airport08:20Prague AirportPrague Airport - T1/20EconomyA Flight from Buzz goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 08/12/2025 16:00:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 09/12/2025 08:20:00. 50 Economy ticket for £70 per person are available. Travel duration is 16h 20m
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FlixBus15h 0m015:55BrusselsNorth Station06:55PragueÚAN Florenc0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 08/12/2025 15:55:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 09/12/2025 06:55:00. 50 Economy ticket for £38 per person are available. Travel duration is 15h 0m
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FlixBus16h 10m007:00BrusselsNorth Station23:10PragueÚAN Florenc0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 08/12/2025 07:00:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 08/12/2025 23:10:00. 50 Economy ticket for £38 per person are available. Travel duration is 16h 10m
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FlixBus16h 40m016:15BrusselsMidi Bus Station08:55PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 08/12/2025 16:15:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 09/12/2025 08:55:00. 50 Economy ticket for £38 per person are available. Travel duration is 16h 40m
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European Sleeper17h 23m019:22BrusselsMidi Bus Station12:45PragueWilsonova Coach Station0EconomyA Bus from European Sleeper goes from Midi Bus Station, Brussels (Belgium) at 08/12/2025 19:22:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 09/12/2025 12:45:00. 50 Economy ticket for £233 per person are available. Travel duration is 17h 23m
Fastest Flights Monday
Fastest Buses Monday
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FlixBus15h 10m017:30BrusselsNorth Station08:40PragueÚAN Florenc0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 09/12/2025 17:30:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 10/12/2025 08:40:00. 50 Economy ticket for £34 per person are available. Travel duration is 15h 10m
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FlixBus15h 25m017:30BrusselsNorth Station08:55PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 09/12/2025 17:30:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 10/12/2025 08:55:00. 50 Economy ticket for £34 per person are available. Travel duration is 15h 25m
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FlixBus16h 40m016:15BrusselsMidi Bus Station08:55PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 09/12/2025 16:15:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 10/12/2025 08:55:00. 50 Economy ticket for £34 per person are available. Travel duration is 16h 40m
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FlixBus17h 50m001:20BrusselsMidi Bus Station19:10PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 09/12/2025 01:20:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 09/12/2025 19:10:00. 50 Economy ticket for £35 per person are available. Travel duration is 17h 50m
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FlixBus18h 35m022:55BrusselsNorth Station17:30PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 09/12/2025 22:55:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 10/12/2025 17:30:00. 50 Economy ticket for £34 per person are available. Travel duration is 18h 35m
Fastest Buses Tuesday
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Smartwings1h 25m008:55Brussels AirportBrussels Airport10:20Prague AirportPrague Airport - T1/20EconomyA Flight from Smartwings goes from Brussels Airport, Brussels Airport (Belgium) at 10/12/2025 08:55:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 10/12/2025 10:20:00. 50 Economy ticket for £61 per person are available. Travel duration is 1h 25m
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Wizz Air5h 0m016:30Brussels South Charleroi AirportBrussels South Charleroi Airport21:30Prague AirportPrague Airport - T1/20EconomyA Flight from Wizz Air goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 10/12/2025 16:30:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 10/12/2025 21:30:00. 50 Economy ticket for £93 per person are available. Travel duration is 5h 0m
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Skyscanner12h 0m009:10Brussels South Charleroi AirportBrussels South Charleroi Airport21:10Prague AirportPrague Airport - T1/20EconomyA Flight from Skyscanner goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 10/12/2025 09:10:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 10/12/2025 21:10:00. 50 Economy ticket for £73 per person are available. Travel duration is 12h 0m
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Buzz22h 25m008:35Brussels South Charleroi AirportBrussels South Charleroi Airport07:00Prague AirportPrague Airport - T1/20EconomyA Flight from Buzz goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 10/12/2025 08:35:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 11/12/2025 07:00:00. 50 Economy ticket for £64 per person are available. Travel duration is 22h 25m
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Ryanair25h 10m018:00Brussels South Charleroi AirportBrussels South Charleroi Airport19:10Prague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 10/12/2025 18:00:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 11/12/2025 19:10:00. 50 Economy ticket for £78 per person are available. Travel duration is 25h 10m
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European Sleeper16h 33m019:22BrusselsMidi Bus Station11:55PragueWilsonova Coach Station0EconomyA Bus from European Sleeper goes from Midi Bus Station, Brussels (Belgium) at 10/12/2025 19:22:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 11/12/2025 11:55:00. 50 Economy ticket for £251 per person are available. Travel duration is 16h 33m
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FlixBus16h 35m017:30BrusselsNorth Station10:05PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 10/12/2025 17:30:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 11/12/2025 10:05:00. 50 Economy ticket for £37 per person are available. Travel duration is 16h 35m
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FlixBus17h 50m016:15BrusselsMidi Bus Station10:05PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 10/12/2025 16:15:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 11/12/2025 10:05:00. 50 Economy ticket for £36 per person are available. Travel duration is 17h 50m
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FlixBus19h 15m016:15BrusselsMidi Bus Station11:30PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 10/12/2025 16:15:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 11/12/2025 11:30:00. 50 Economy ticket for £37 per person are available. Travel duration is 19h 15m
Fastest Flights Wednesday
Fastest Buses Wednesday
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FlixBus18h 10m014:30BrusselsNorth Station08:40PragueÚAN Florenc0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 11/12/2025 14:30:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 12/12/2025 08:40:00. 50 Economy ticket for £43 per person are available. Travel duration is 18h 10m
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FlixBus18h 35m009:00BrusselsNorth Station03:35PragueÚAN Florenc0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 11/12/2025 09:00:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 12/12/2025 03:35:00. 50 Economy ticket for £40 per person are available. Travel duration is 18h 35m
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FlixBus19h 15m000:45BrusselsMidi Bus Station20:00PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 11/12/2025 00:45:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 11/12/2025 20:00:00. 50 Economy ticket for £45 per person are available. Travel duration is 19h 15m
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FlixBus20h 50m021:25BrusselsNorth Station18:15PragueHolesovice0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 11/12/2025 21:25:00 to Holesovice, Prague (Czech Republic) arriving at 12/12/2025 18:15:00. 50 Economy ticket for £39 per person are available. Travel duration is 20h 50m
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FlixBus20h 55m006:20BrusselsNorth Station03:15PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 11/12/2025 06:20:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 12/12/2025 03:15:00. 50 Economy ticket for £40 per person are available. Travel duration is 20h 55m
Fastest Buses Thursday
Here you will find all operators and timetables for a
Bus from Brussels to Prague
What are the most popular stations in Brussels and Prague?
In Brussels, you will usually depart from Midi Bus Station, North Station or Gare Centrale, while in Prague you will be arriving at Wilsonova Coach Station, ÚAN Florenc or Černý Most, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Prague from Brussels? With 6 connections between 3 Bus and Flight operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Brussels and Prague, you can pay as low as £30 with a Flight from Ryanair.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Smartwings: you will get to Prague in just 1h 25m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Brussels and Prague are FlixBus, European Sleeper and Ryanair, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Brussels and Prague is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Saint-Gilles or to Horoměřice, and look at flights from Brussels South Charleroi Airport, and landing at Prague Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Brussels to Prague?
The most popular companies between Brussels and Prague, are FlixBus, European Sleeper and Ryanair. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: FlixBus and European Sleeper
Airlines: Ryanair, Smartwings, Buzz and 4 more.
All you need to know when you travel from Brussels to Prague
Check all information on comfort and services on all modes of transports from Brussels to Prague. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Brussels to Prague
How can I reach Prague from Brussels?
Every day, there are on average 6 connections between Bus and Flight, with which you can get to Prague from Brussels.
How far is Prague from Brussels?
The distance between Brussels and Prague is 718.5 km.
What is the most ecofriendly mode of transport between Brussels and Prague?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 19 kgs of CO2, a train 25 kgs, a car 122 kgs, and a flight 177 kgs.
What is the cheapest mode of transport from Brussels to Prague?
You can get to Prague with just £30 by taking a Flight from Ryanair.
What is the fastest way to get from Brussels to Prague?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Prague in just 1h 25m with a Flight from Smartwings.
More routes to Brussels and to Prague
Looking for more options? Here you can see the most popular routes to Brussels and to Prague. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Brussels
- Amiens to Brussels
- Amsterdam to Brussels
- Antwerp to Brussels
- Barcelona to Brussels
- Basel to Brussels
- Birmingham to Brussels
- Bologna to Brussels
- Bordeaux to Brussels
- Brussels South Charleroi Airport to Brussels
- Dusseldorf to Brussels
- Ghent to Brussels
- Glasgow to Brussels
- Lille to Brussels
- Linz to Brussels
- Lisbon to Brussels
- London to Brussels
- Lyon to Brussels
- Munich to Brussels
- Nantes to Brussels
- Newcastle upon Tyne to Brussels
- Paris to Brussels
- The Hague to Brussels
- Toulouse to Brussels
- Zurich to Brussels
- Trips to Prague
- Berlin to Prague
- Bologna to Prague
- Cologne/Bonn Airport to Prague
- Dortmund to Prague
- Dresden to Prague
- Hamburg to Prague
- Hradec Kralove to Prague
- Humpolec to Prague
- Jihlava to Prague
- Krakow to Prague
- Kysak to Prague
- Leipzig to Prague
- London to Prague
- Milan to Prague
- Munich to Prague
- Ostrava to Prague
- Pardubice to Prague
- Prague Airport to Prague
- St. Gallen to Prague
- Stuttgart to Prague
- Turin to Prague
- Vienna to Prague
- Warsaw Chopin Airport to Prague
- Zurich to Prague

