What is the best way to travel from Brussels to Prague?
Looking for a trip? Check and compare all the available Buses and Flights to Prague from Brussels. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 2 available companies to find your perfect trip!
What is the cheapest way to reach Prague from Brussels?
You can reach Prague with just £57 by taking a Flight from Smartwings, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
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Buzz1h 30m020:20Brussels South Charleroi AirportBrussels South Charleroi Airport21:50Prague AirportPrague Airport - T1/20EconomyA Flight from Buzz goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 19/12/2025 20:20:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 19/12/2025 21:50:00. 50 Economy ticket for £62 per person are available. Travel duration is 1h 30m
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Ryanair1h 25m009:55Brussels AirportBrussels Airport11:20Prague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Brussels Airport, Brussels Airport (Belgium) at 19/12/2025 09:55:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 19/12/2025 11:20:00. 50 Economy ticket for £63 per person are available. Travel duration is 1h 25m
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Smartwings1h 25m019:30Brussels AirportBrussels Airport20:55Prague AirportPrague Airport - T1/20EconomyA Flight from Smartwings goes from Brussels Airport, Brussels Airport (Belgium) at 19/12/2025 19:30:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 19/12/2025 20:55:00. 50 Economy ticket for £94 per person are available. Travel duration is 1h 25m
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Austrian Airlines6h 10m009:50Brussels AirportBrussels Airport16:00Prague AirportPrague Airport - T1/20EconomyA Flight from Austrian Airlines goes from Brussels Airport, Brussels Airport (Belgium) at 19/12/2025 09:50:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 19/12/2025 16:00:00. 50 Economy ticket for £114 per person are available. Travel duration is 6h 10m
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Brussels Airlines3h 55m010:00Brussels AirportBrussels Airport13:55Prague AirportPrague Airport - T1/20EconomyA Flight from Brussels Airlines goes from Brussels Airport, Brussels Airport (Belgium) at 19/12/2025 10:00:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 19/12/2025 13:55:00. 50 Economy ticket for £130 per person are available. Travel duration is 3h 55m
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FlixBus13h 55m010:30BrusselsNorth Station00:25PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 19/12/2025 10:30:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 20/12/2025 00:25:00. 50 Economy ticket for £74 per person are available. Travel duration is 13h 55m
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FlixBus13h 35m010:30BrusselsNorth Station00:05PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 19/12/2025 10:30:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 20/12/2025 00:05:00. 50 Economy ticket for £74 per person are available. Travel duration is 13h 35m
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FlixBus17h 40m013:00BrusselsNorth Station06:40PragueÚAN Florenc0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 19/12/2025 13:00:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 20/12/2025 06:40:00. 50 Economy ticket for £99 per person are available. Travel duration is 17h 40m
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European Sleeper15h 57m019:22BrusselsMidi Bus Station11:19PragueWilsonova Coach Station0EconomyA Bus from European Sleeper goes from Midi Bus Station, Brussels (Belgium) at 19/12/2025 19:22:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 20/12/2025 11:19:00. 50 Economy ticket for £464 per person are available. Travel duration is 15h 57m
Cheapest Flights Friday
Cheapest Buses Friday
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FlixBus18h 45m021:25BrusselsNorth Station16:10PragueČerný Most0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 20/12/2025 21:25:00 to Černý Most, Prague (Czech Republic) arriving at 21/12/2025 16:10:00. 50 Economy ticket for £80 per person are available. Travel duration is 18h 45m
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FlixBus15h 0m022:10BrusselsMidi Bus Station13:10PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 20/12/2025 22:10:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 21/12/2025 13:10:00. 50 Economy ticket for £88 per person are available. Travel duration is 15h 0m
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FlixBus13h 35m010:30BrusselsNorth Station00:05PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 20/12/2025 10:30:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 21/12/2025 00:05:00. 50 Economy ticket for £88 per person are available. Travel duration is 13h 35m
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FlixBus15h 10m017:30BrusselsNorth Station08:40PragueÚAN Florenc0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 20/12/2025 17:30:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 21/12/2025 08:40:00. 50 Economy ticket for £90 per person are available. Travel duration is 15h 10m
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FlixBus19h 35m022:00BrusselsNorth Station17:35PragueHradčanská0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 20/12/2025 22:00:00 to Hradčanská, Prague (Czech Republic) arriving at 21/12/2025 17:35:00. 50 Economy ticket for £90 per person are available. Travel duration is 19h 35m
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Skyscanner16h 10m017:30Brussels South Charleroi AirportBrussels South Charleroi Airport09:40Prague AirportPrague Airport - T1/20EconomyA Flight from Skyscanner goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 20/12/2025 17:30:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 21/12/2025 09:40:00. 50 Economy ticket for £92 per person are available. Travel duration is 16h 10m
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Ryanair24h 10m021:10Brussels South Charleroi AirportBrussels South Charleroi Airport21:20Prague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 20/12/2025 21:10:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 21/12/2025 21:20:00. 50 Economy ticket for £98 per person are available. Travel duration is 24h 10m
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Lauda Europe27h 15m020:35Brussels South Charleroi AirportBrussels South Charleroi Airport23:50Prague AirportPrague Airport - T1/20EconomyA Flight from Lauda Europe goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 20/12/2025 20:35:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 21/12/2025 23:50:00. 50 Economy ticket for £133 per person are available. Travel duration is 27h 15m
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LOT Polish Airlines / Polskie Linie Lotnicze13h 10m019:40Brussels AirportBrussels Airport08:50Prague AirportPrague Airport - T1/20EconomyA Flight from LOT Polish Airlines / Polskie Linie Lotnicze goes from Brussels Airport, Brussels Airport (Belgium) at 20/12/2025 19:40:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 21/12/2025 08:50:00. 50 Economy ticket for £180 per person are available. Travel duration is 13h 10m
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Smartwings1h 25m008:55Brussels AirportBrussels Airport10:20Prague AirportPrague Airport - T1/20EconomyA Flight from Smartwings goes from Brussels Airport, Brussels Airport (Belgium) at 20/12/2025 08:55:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 20/12/2025 10:20:00. 50 Economy ticket for £188 per person are available. Travel duration is 1h 25m
Cheapest Buses Saturday
Cheapest Flights Saturday
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Ryanair1h 25m020:30Brussels AirportBrussels Airport21:55Prague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Brussels Airport, Brussels Airport (Belgium) at 21/12/2025 20:30:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 21/12/2025 21:55:00. 50 Economy ticket for £58 per person are available. Travel duration is 1h 25m
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Smartwings1h 25m019:30Brussels AirportBrussels Airport20:55Prague AirportPrague Airport - T1/20EconomyA Flight from Smartwings goes from Brussels Airport, Brussels Airport (Belgium) at 21/12/2025 19:30:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 21/12/2025 20:55:00. 50 Economy ticket for £61 per person are available. Travel duration is 1h 25m
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Brussels Airlines1h 25m020:45Brussels AirportBrussels Airport22:10Prague AirportPrague Airport - T1/20EconomyA Flight from Brussels Airlines goes from Brussels Airport, Brussels Airport (Belgium) at 21/12/2025 20:45:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 21/12/2025 22:10:00. 50 Economy ticket for £80 per person are available. Travel duration is 1h 25m
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Skyscanner12h 15m009:00Brussels South Charleroi AirportBrussels South Charleroi Airport21:15Prague AirportPrague Airport - T1/20EconomyA Flight from Skyscanner goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 21/12/2025 09:00:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 21/12/2025 21:15:00. 50 Economy ticket for £88 per person are available. Travel duration is 12h 15m
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LOT Polish Airlines / Polskie Linie Lotnicze16h 30m019:40Brussels AirportBrussels Airport12:10Prague AirportPrague Airport - T1/20EconomyA Flight from LOT Polish Airlines / Polskie Linie Lotnicze goes from Brussels Airport, Brussels Airport (Belgium) at 21/12/2025 19:40:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 22/12/2025 12:10:00. 50 Economy ticket for £134 per person are available. Travel duration is 16h 30m
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FlixBus13h 35m010:30BrusselsNorth Station00:05PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 21/12/2025 10:30:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 22/12/2025 00:05:00. 50 Economy ticket for £74 per person are available. Travel duration is 13h 35m
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FlixBus13h 55m010:30BrusselsNorth Station00:25PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 21/12/2025 10:30:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 22/12/2025 00:25:00. 50 Economy ticket for £74 per person are available. Travel duration is 13h 55m
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FlixBus18h 45m021:25BrusselsNorth Station16:10PragueČerný Most0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 21/12/2025 21:25:00 to Černý Most, Prague (Czech Republic) arriving at 22/12/2025 16:10:00. 50 Economy ticket for £74 per person are available. Travel duration is 18h 45m
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FlixBus19h 15m016:15BrusselsMidi Bus Station11:30PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 21/12/2025 16:15:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 22/12/2025 11:30:00. 50 Economy ticket for £84 per person are available. Travel duration is 19h 15m
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FlixBus12h 50m009:30BrusselsNorth Station22:20PragueÚAN Florenc0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 21/12/2025 09:30:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 21/12/2025 22:20:00. 50 Economy ticket for £86 per person are available. Travel duration is 12h 50m
Cheapest Flights Sunday
Cheapest Buses Sunday
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Pegasus Airlines1h 25m019:30Brussels AirportBrussels Airport20:55Prague AirportPrague Airport - T1/20EconomyA Flight from Pegasus Airlines goes from Brussels Airport, Brussels Airport (Belgium) at 22/12/2025 19:30:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 22/12/2025 20:55:00. 50 Economy ticket for £65 per person are available. Travel duration is 1h 25m
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Smartwings1h 25m019:30Brussels AirportBrussels Airport20:55Prague AirportPrague Airport - T1/20EconomyA Flight from Smartwings goes from Brussels Airport, Brussels Airport (Belgium) at 22/12/2025 19:30:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 22/12/2025 20:55:00. 50 Economy ticket for £93 per person are available. Travel duration is 1h 25m
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Ryanair10h 40m007:35Brussels South Charleroi AirportBrussels South Charleroi Airport18:15Prague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 22/12/2025 07:35:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 22/12/2025 18:15:00. 50 Economy ticket for £95 per person are available. Travel duration is 10h 40m
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Air Malta23h 25m020:25Brussels AirportBrussels Airport19:50Prague AirportPrague Airport - T1/20EconomyA Flight from Air Malta goes from Brussels Airport, Brussels Airport (Belgium) at 22/12/2025 20:25:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 23/12/2025 19:50:00. 50 Economy ticket for £125 per person are available. Travel duration is 23h 25m
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EasyJet Airline7h 5m009:25Brussels AirportBrussels Airport16:30Prague AirportPrague Airport - T1/20EconomyA Flight from EasyJet Airline goes from Brussels Airport, Brussels Airport (Belgium) at 22/12/2025 09:25:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 22/12/2025 16:30:00. 50 Economy ticket for £143 per person are available. Travel duration is 7h 5m
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FlixBus18h 45m021:25BrusselsNorth Station16:10PragueČerný Most0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 22/12/2025 21:25:00 to Černý Most, Prague (Czech Republic) arriving at 23/12/2025 16:10:00. 50 Economy ticket for £66 per person are available. Travel duration is 18h 45m
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FlixBus13h 35m010:30BrusselsNorth Station00:05PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 22/12/2025 10:30:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 23/12/2025 00:05:00. 50 Economy ticket for £69 per person are available. Travel duration is 13h 35m
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FlixBus17h 55m003:15BrusselsMidi Bus Station21:10PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 22/12/2025 03:15:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 22/12/2025 21:10:00. 50 Economy ticket for £70 per person are available. Travel duration is 17h 55m
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European Sleeper15h 57m019:22BrusselsMidi Bus Station11:19PragueWilsonova Coach Station0EconomyA Bus from European Sleeper goes from Midi Bus Station, Brussels (Belgium) at 22/12/2025 19:22:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 23/12/2025 11:19:00. 50 Economy ticket for £149 per person are available. Travel duration is 15h 57m
Cheapest Flights Monday
Cheapest Buses Monday
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FlixBus13h 35m010:30BrusselsNorth Station00:05PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 23/12/2025 10:30:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 24/12/2025 00:05:00. 50 Economy ticket for £64 per person are available. Travel duration is 13h 35m
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FlixBus13h 55m010:30BrusselsNorth Station00:25PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 23/12/2025 10:30:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 24/12/2025 00:25:00. 50 Economy ticket for £64 per person are available. Travel duration is 13h 55m
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FlixBus15h 10m017:30BrusselsNorth Station08:40PragueÚAN Florenc0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 23/12/2025 17:30:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 24/12/2025 08:40:00. 50 Economy ticket for £69 per person are available. Travel duration is 15h 10m
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FlixBus16h 40m016:15BrusselsMidi Bus Station08:55PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 23/12/2025 16:15:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 24/12/2025 08:55:00. 50 Economy ticket for £70 per person are available. Travel duration is 16h 40m
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FlixBus15h 25m017:30BrusselsNorth Station08:55PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 23/12/2025 17:30:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 24/12/2025 08:55:00. 50 Economy ticket for £70 per person are available. Travel duration is 15h 25m
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Smartwings1h 25m019:30Brussels AirportBrussels Airport20:55Prague AirportPrague Airport - T1/20EconomyA Flight from Smartwings goes from Brussels Airport, Brussels Airport (Belgium) at 23/12/2025 19:30:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 23/12/2025 20:55:00. 50 Economy ticket for £72 per person are available. Travel duration is 1h 25m
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Buzz1h 30m019:25Brussels South Charleroi AirportBrussels South Charleroi Airport20:55Prague AirportPrague Airport - T1/20EconomyA Flight from Buzz goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 23/12/2025 19:25:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 23/12/2025 20:55:00. 50 Economy ticket for £79 per person are available. Travel duration is 1h 30m
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Wizz Air11h 5m009:45Brussels South Charleroi AirportBrussels South Charleroi Airport20:50Prague AirportPrague Airport - T1/20EconomyA Flight from Wizz Air goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 23/12/2025 09:45:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 23/12/2025 20:50:00. 50 Economy ticket for £101 per person are available. Travel duration is 11h 5m
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Ryanair15h 30m006:25Brussels South Charleroi AirportBrussels South Charleroi Airport21:55Prague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 23/12/2025 06:25:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 23/12/2025 21:55:00. 50 Economy ticket for £115 per person are available. Travel duration is 15h 30m
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Skyscanner5h 10m009:20Brussels South Charleroi AirportBrussels South Charleroi Airport14:30Prague AirportPrague Airport - T1/20EconomyA Flight from Skyscanner goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 23/12/2025 09:20:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 23/12/2025 14:30:00. 50 Economy ticket for £136 per person are available. Travel duration is 5h 10m
Cheapest Buses Tuesday
Cheapest Flights Tuesday
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FlixBus14h 40m016:15BrusselsMidi Bus Station06:55PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 24/12/2025 16:15:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 25/12/2025 06:55:00. 50 Economy ticket for £58 per person are available. Travel duration is 14h 40m
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FlixBus12h 50m009:30BrusselsNorth Station22:20PragueÚAN Florenc0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 24/12/2025 09:30:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 24/12/2025 22:20:00. 50 Economy ticket for £60 per person are available. Travel duration is 12h 50m
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FlixBus13h 55m010:30BrusselsNorth Station00:25PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 24/12/2025 10:30:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 25/12/2025 00:25:00. 50 Economy ticket for £60 per person are available. Travel duration is 13h 55m
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European Sleeper15h 57m019:22BrusselsMidi Bus Station11:19PragueWilsonova Coach Station0EconomyA Bus from European Sleeper goes from Midi Bus Station, Brussels (Belgium) at 24/12/2025 19:22:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 25/12/2025 11:19:00. 50 Economy ticket for £184 per person are available. Travel duration is 15h 57m
Cheapest Buses Wednesday
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Smartwings1h 25m008:55Brussels AirportBrussels Airport10:20Prague AirportPrague Airport - T1/20EconomyA Flight from Smartwings goes from Brussels Airport, Brussels Airport (Belgium) at 25/12/2025 08:55:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 25/12/2025 10:20:00. 50 Economy ticket for £57 per person are available. Travel duration is 1h 25m
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LC Perú25h 5m021:00Brussels South Charleroi AirportBrussels South Charleroi Airport22:05Prague AirportPrague Airport - T1/20EconomyA Flight from LC Perú goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 25/12/2025 21:00:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 26/12/2025 22:05:00. 50 Economy ticket for £92 per person are available. Travel duration is 25h 5m
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Wizz Air11h 35m019:55Brussels South Charleroi AirportBrussels South Charleroi Airport07:30Prague AirportPrague Airport - T1/20EconomyA Flight from Wizz Air goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 25/12/2025 19:55:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 26/12/2025 07:30:00. 50 Economy ticket for £149 per person are available. Travel duration is 11h 35m
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SAS Scandinavian Airlines4h 0m010:20Brussels AirportBrussels Airport14:20Prague AirportPrague Airport - T1/20EconomyA Flight from SAS Scandinavian Airlines goes from Brussels Airport, Brussels Airport (Belgium) at 25/12/2025 10:20:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 25/12/2025 14:20:00. 50 Economy ticket for £172 per person are available. Travel duration is 4h 0m
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Brussels Airlines1h 25m009:25Brussels AirportBrussels Airport10:50Prague AirportPrague Airport - T1/20EconomyA Flight from Brussels Airlines goes from Brussels Airport, Brussels Airport (Belgium) at 25/12/2025 09:25:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 25/12/2025 10:50:00. 50 Economy ticket for £174 per person are available. Travel duration is 1h 25m
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FlixBus14h 40m016:15BrusselsMidi Bus Station06:55PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 25/12/2025 16:15:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 26/12/2025 06:55:00. 50 Economy ticket for £61 per person are available. Travel duration is 14h 40m
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FlixBus13h 55m010:30BrusselsNorth Station00:25PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 25/12/2025 10:30:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 26/12/2025 00:25:00. 50 Economy ticket for £61 per person are available. Travel duration is 13h 55m
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FlixBus13h 35m010:30BrusselsNorth Station00:05PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 25/12/2025 10:30:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 26/12/2025 00:05:00. 50 Economy ticket for £61 per person are available. Travel duration is 13h 35m
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FlixBus15h 0m022:10BrusselsMidi Bus Station13:10PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 25/12/2025 22:10:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 26/12/2025 13:10:00. 50 Economy ticket for £67 per person are available. Travel duration is 15h 0m
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FlixBus18h 35m016:15BrusselsMidi Bus Station10:50PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 25/12/2025 16:15:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 26/12/2025 10:50:00. 50 Economy ticket for £78 per person are available. Travel duration is 18h 35m
Cheapest Flights Thursday
Cheapest Buses Thursday
What are the fastest trips from Brussels to Prague?
You can get to Prague from Brussels in just 1h 25m with a Flight from Ryanair. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
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Ryanair1h 25m009:55Brussels AirportBrussels Airport11:20Prague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Brussels Airport, Brussels Airport (Belgium) at 19/12/2025 09:55:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 19/12/2025 11:20:00. 50 Economy ticket for £63 per person are available. Travel duration is 1h 25m
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Smartwings1h 25m019:30Brussels AirportBrussels Airport20:55Prague AirportPrague Airport - T1/20EconomyA Flight from Smartwings goes from Brussels Airport, Brussels Airport (Belgium) at 19/12/2025 19:30:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 19/12/2025 20:55:00. 50 Economy ticket for £94 per person are available. Travel duration is 1h 25m
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Buzz1h 30m020:20Brussels South Charleroi AirportBrussels South Charleroi Airport21:50Prague AirportPrague Airport - T1/20EconomyA Flight from Buzz goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 19/12/2025 20:20:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 19/12/2025 21:50:00. 50 Economy ticket for £62 per person are available. Travel duration is 1h 30m
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Brussels Airlines3h 55m010:00Brussels AirportBrussels Airport13:55Prague AirportPrague Airport - T1/20EconomyA Flight from Brussels Airlines goes from Brussels Airport, Brussels Airport (Belgium) at 19/12/2025 10:00:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 19/12/2025 13:55:00. 50 Economy ticket for £130 per person are available. Travel duration is 3h 55m
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Austrian Airlines6h 10m009:50Brussels AirportBrussels Airport16:00Prague AirportPrague Airport - T1/20EconomyA Flight from Austrian Airlines goes from Brussels Airport, Brussels Airport (Belgium) at 19/12/2025 09:50:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 19/12/2025 16:00:00. 50 Economy ticket for £114 per person are available. Travel duration is 6h 10m
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FlixBus13h 35m010:30BrusselsNorth Station00:05PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 19/12/2025 10:30:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 20/12/2025 00:05:00. 50 Economy ticket for £74 per person are available. Travel duration is 13h 35m
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FlixBus13h 55m010:30BrusselsNorth Station00:25PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 19/12/2025 10:30:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 20/12/2025 00:25:00. 50 Economy ticket for £74 per person are available. Travel duration is 13h 55m
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European Sleeper15h 57m019:22BrusselsMidi Bus Station11:19PragueWilsonova Coach Station0EconomyA Bus from European Sleeper goes from Midi Bus Station, Brussels (Belgium) at 19/12/2025 19:22:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 20/12/2025 11:19:00. 50 Economy ticket for £464 per person are available. Travel duration is 15h 57m
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FlixBus17h 40m013:00BrusselsNorth Station06:40PragueÚAN Florenc0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 19/12/2025 13:00:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 20/12/2025 06:40:00. 50 Economy ticket for £99 per person are available. Travel duration is 17h 40m
Fastest Flights Friday
Fastest Buses Friday
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Smartwings1h 25m008:55Brussels AirportBrussels Airport10:20Prague AirportPrague Airport - T1/20EconomyA Flight from Smartwings goes from Brussels Airport, Brussels Airport (Belgium) at 20/12/2025 08:55:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 20/12/2025 10:20:00. 50 Economy ticket for £188 per person are available. Travel duration is 1h 25m
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LOT Polish Airlines / Polskie Linie Lotnicze13h 10m019:40Brussels AirportBrussels Airport08:50Prague AirportPrague Airport - T1/20EconomyA Flight from LOT Polish Airlines / Polskie Linie Lotnicze goes from Brussels Airport, Brussels Airport (Belgium) at 20/12/2025 19:40:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 21/12/2025 08:50:00. 50 Economy ticket for £180 per person are available. Travel duration is 13h 10m
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Skyscanner16h 10m017:30Brussels South Charleroi AirportBrussels South Charleroi Airport09:40Prague AirportPrague Airport - T1/20EconomyA Flight from Skyscanner goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 20/12/2025 17:30:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 21/12/2025 09:40:00. 50 Economy ticket for £92 per person are available. Travel duration is 16h 10m
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Ryanair24h 10m021:10Brussels South Charleroi AirportBrussels South Charleroi Airport21:20Prague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 20/12/2025 21:10:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 21/12/2025 21:20:00. 50 Economy ticket for £98 per person are available. Travel duration is 24h 10m
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Lauda Europe27h 15m020:35Brussels South Charleroi AirportBrussels South Charleroi Airport23:50Prague AirportPrague Airport - T1/20EconomyA Flight from Lauda Europe goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 20/12/2025 20:35:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 21/12/2025 23:50:00. 50 Economy ticket for £133 per person are available. Travel duration is 27h 15m
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FlixBus13h 35m010:30BrusselsNorth Station00:05PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 20/12/2025 10:30:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 21/12/2025 00:05:00. 50 Economy ticket for £88 per person are available. Travel duration is 13h 35m
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FlixBus15h 0m022:10BrusselsMidi Bus Station13:10PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 20/12/2025 22:10:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 21/12/2025 13:10:00. 50 Economy ticket for £88 per person are available. Travel duration is 15h 0m
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FlixBus15h 10m017:30BrusselsNorth Station08:40PragueÚAN Florenc0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 20/12/2025 17:30:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 21/12/2025 08:40:00. 50 Economy ticket for £90 per person are available. Travel duration is 15h 10m
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FlixBus18h 45m021:25BrusselsNorth Station16:10PragueČerný Most0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 20/12/2025 21:25:00 to Černý Most, Prague (Czech Republic) arriving at 21/12/2025 16:10:00. 50 Economy ticket for £80 per person are available. Travel duration is 18h 45m
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FlixBus19h 35m022:00BrusselsNorth Station17:35PragueHradčanská0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 20/12/2025 22:00:00 to Hradčanská, Prague (Czech Republic) arriving at 21/12/2025 17:35:00. 50 Economy ticket for £90 per person are available. Travel duration is 19h 35m
Fastest Flights Saturday
Fastest Buses Saturday
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Ryanair1h 25m020:30Brussels AirportBrussels Airport21:55Prague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Brussels Airport, Brussels Airport (Belgium) at 21/12/2025 20:30:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 21/12/2025 21:55:00. 50 Economy ticket for £58 per person are available. Travel duration is 1h 25m
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Smartwings1h 25m019:30Brussels AirportBrussels Airport20:55Prague AirportPrague Airport - T1/20EconomyA Flight from Smartwings goes from Brussels Airport, Brussels Airport (Belgium) at 21/12/2025 19:30:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 21/12/2025 20:55:00. 50 Economy ticket for £61 per person are available. Travel duration is 1h 25m
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Brussels Airlines1h 25m020:45Brussels AirportBrussels Airport22:10Prague AirportPrague Airport - T1/20EconomyA Flight from Brussels Airlines goes from Brussels Airport, Brussels Airport (Belgium) at 21/12/2025 20:45:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 21/12/2025 22:10:00. 50 Economy ticket for £80 per person are available. Travel duration is 1h 25m
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Skyscanner12h 15m009:00Brussels South Charleroi AirportBrussels South Charleroi Airport21:15Prague AirportPrague Airport - T1/20EconomyA Flight from Skyscanner goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 21/12/2025 09:00:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 21/12/2025 21:15:00. 50 Economy ticket for £88 per person are available. Travel duration is 12h 15m
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LOT Polish Airlines / Polskie Linie Lotnicze16h 30m019:40Brussels AirportBrussels Airport12:10Prague AirportPrague Airport - T1/20EconomyA Flight from LOT Polish Airlines / Polskie Linie Lotnicze goes from Brussels Airport, Brussels Airport (Belgium) at 21/12/2025 19:40:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 22/12/2025 12:10:00. 50 Economy ticket for £134 per person are available. Travel duration is 16h 30m
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FlixBus12h 50m009:30BrusselsNorth Station22:20PragueÚAN Florenc0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 21/12/2025 09:30:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 21/12/2025 22:20:00. 50 Economy ticket for £86 per person are available. Travel duration is 12h 50m
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FlixBus13h 35m010:30BrusselsNorth Station00:05PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 21/12/2025 10:30:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 22/12/2025 00:05:00. 50 Economy ticket for £74 per person are available. Travel duration is 13h 35m
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FlixBus13h 55m010:30BrusselsNorth Station00:25PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 21/12/2025 10:30:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 22/12/2025 00:25:00. 50 Economy ticket for £74 per person are available. Travel duration is 13h 55m
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FlixBus18h 45m021:25BrusselsNorth Station16:10PragueČerný Most0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 21/12/2025 21:25:00 to Černý Most, Prague (Czech Republic) arriving at 22/12/2025 16:10:00. 50 Economy ticket for £74 per person are available. Travel duration is 18h 45m
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FlixBus19h 15m016:15BrusselsMidi Bus Station11:30PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 21/12/2025 16:15:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 22/12/2025 11:30:00. 50 Economy ticket for £84 per person are available. Travel duration is 19h 15m
Fastest Flights Sunday
Fastest Buses Sunday
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Pegasus Airlines1h 25m019:30Brussels AirportBrussels Airport20:55Prague AirportPrague Airport - T1/20EconomyA Flight from Pegasus Airlines goes from Brussels Airport, Brussels Airport (Belgium) at 22/12/2025 19:30:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 22/12/2025 20:55:00. 50 Economy ticket for £65 per person are available. Travel duration is 1h 25m
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Smartwings1h 25m019:30Brussels AirportBrussels Airport20:55Prague AirportPrague Airport - T1/20EconomyA Flight from Smartwings goes from Brussels Airport, Brussels Airport (Belgium) at 22/12/2025 19:30:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 22/12/2025 20:55:00. 50 Economy ticket for £93 per person are available. Travel duration is 1h 25m
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EasyJet Airline7h 5m009:25Brussels AirportBrussels Airport16:30Prague AirportPrague Airport - T1/20EconomyA Flight from EasyJet Airline goes from Brussels Airport, Brussels Airport (Belgium) at 22/12/2025 09:25:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 22/12/2025 16:30:00. 50 Economy ticket for £143 per person are available. Travel duration is 7h 5m
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Ryanair10h 40m007:35Brussels South Charleroi AirportBrussels South Charleroi Airport18:15Prague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 22/12/2025 07:35:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 22/12/2025 18:15:00. 50 Economy ticket for £95 per person are available. Travel duration is 10h 40m
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Air Malta23h 25m020:25Brussels AirportBrussels Airport19:50Prague AirportPrague Airport - T1/20EconomyA Flight from Air Malta goes from Brussels Airport, Brussels Airport (Belgium) at 22/12/2025 20:25:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 23/12/2025 19:50:00. 50 Economy ticket for £125 per person are available. Travel duration is 23h 25m
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FlixBus13h 35m010:30BrusselsNorth Station00:05PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 22/12/2025 10:30:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 23/12/2025 00:05:00. 50 Economy ticket for £69 per person are available. Travel duration is 13h 35m
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European Sleeper15h 57m019:22BrusselsMidi Bus Station11:19PragueWilsonova Coach Station0EconomyA Bus from European Sleeper goes from Midi Bus Station, Brussels (Belgium) at 22/12/2025 19:22:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 23/12/2025 11:19:00. 50 Economy ticket for £149 per person are available. Travel duration is 15h 57m
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FlixBus17h 55m003:15BrusselsMidi Bus Station21:10PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 22/12/2025 03:15:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 22/12/2025 21:10:00. 50 Economy ticket for £70 per person are available. Travel duration is 17h 55m
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FlixBus18h 45m021:25BrusselsNorth Station16:10PragueČerný Most0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 22/12/2025 21:25:00 to Černý Most, Prague (Czech Republic) arriving at 23/12/2025 16:10:00. 50 Economy ticket for £66 per person are available. Travel duration is 18h 45m
Fastest Flights Monday
Fastest Buses Monday
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Smartwings1h 25m019:30Brussels AirportBrussels Airport20:55Prague AirportPrague Airport - T1/20EconomyA Flight from Smartwings goes from Brussels Airport, Brussels Airport (Belgium) at 23/12/2025 19:30:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 23/12/2025 20:55:00. 50 Economy ticket for £72 per person are available. Travel duration is 1h 25m
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Buzz1h 30m019:25Brussels South Charleroi AirportBrussels South Charleroi Airport20:55Prague AirportPrague Airport - T1/20EconomyA Flight from Buzz goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 23/12/2025 19:25:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 23/12/2025 20:55:00. 50 Economy ticket for £79 per person are available. Travel duration is 1h 30m
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Skyscanner5h 10m009:20Brussels South Charleroi AirportBrussels South Charleroi Airport14:30Prague AirportPrague Airport - T1/20EconomyA Flight from Skyscanner goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 23/12/2025 09:20:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 23/12/2025 14:30:00. 50 Economy ticket for £136 per person are available. Travel duration is 5h 10m
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Wizz Air11h 5m009:45Brussels South Charleroi AirportBrussels South Charleroi Airport20:50Prague AirportPrague Airport - T1/20EconomyA Flight from Wizz Air goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 23/12/2025 09:45:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 23/12/2025 20:50:00. 50 Economy ticket for £101 per person are available. Travel duration is 11h 5m
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Ryanair15h 30m006:25Brussels South Charleroi AirportBrussels South Charleroi Airport21:55Prague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 23/12/2025 06:25:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 23/12/2025 21:55:00. 50 Economy ticket for £115 per person are available. Travel duration is 15h 30m
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FlixBus13h 35m010:30BrusselsNorth Station00:05PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 23/12/2025 10:30:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 24/12/2025 00:05:00. 50 Economy ticket for £64 per person are available. Travel duration is 13h 35m
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FlixBus13h 55m010:30BrusselsNorth Station00:25PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 23/12/2025 10:30:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 24/12/2025 00:25:00. 50 Economy ticket for £64 per person are available. Travel duration is 13h 55m
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FlixBus15h 10m017:30BrusselsNorth Station08:40PragueÚAN Florenc0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 23/12/2025 17:30:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 24/12/2025 08:40:00. 50 Economy ticket for £69 per person are available. Travel duration is 15h 10m
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FlixBus15h 25m017:30BrusselsNorth Station08:55PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 23/12/2025 17:30:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 24/12/2025 08:55:00. 50 Economy ticket for £70 per person are available. Travel duration is 15h 25m
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FlixBus16h 40m016:15BrusselsMidi Bus Station08:55PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 23/12/2025 16:15:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 24/12/2025 08:55:00. 50 Economy ticket for £70 per person are available. Travel duration is 16h 40m
Fastest Flights Tuesday
Fastest Buses Tuesday
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FlixBus12h 50m009:30BrusselsNorth Station22:20PragueÚAN Florenc0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 24/12/2025 09:30:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 24/12/2025 22:20:00. 50 Economy ticket for £60 per person are available. Travel duration is 12h 50m
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FlixBus13h 55m010:30BrusselsNorth Station00:25PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 24/12/2025 10:30:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 25/12/2025 00:25:00. 50 Economy ticket for £60 per person are available. Travel duration is 13h 55m
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FlixBus14h 40m016:15BrusselsMidi Bus Station06:55PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 24/12/2025 16:15:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 25/12/2025 06:55:00. 50 Economy ticket for £58 per person are available. Travel duration is 14h 40m
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European Sleeper15h 57m019:22BrusselsMidi Bus Station11:19PragueWilsonova Coach Station0EconomyA Bus from European Sleeper goes from Midi Bus Station, Brussels (Belgium) at 24/12/2025 19:22:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 25/12/2025 11:19:00. 50 Economy ticket for £184 per person are available. Travel duration is 15h 57m
Fastest Buses Wednesday
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Smartwings1h 25m008:55Brussels AirportBrussels Airport10:20Prague AirportPrague Airport - T1/20EconomyA Flight from Smartwings goes from Brussels Airport, Brussels Airport (Belgium) at 25/12/2025 08:55:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 25/12/2025 10:20:00. 50 Economy ticket for £57 per person are available. Travel duration is 1h 25m
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Brussels Airlines1h 25m009:25Brussels AirportBrussels Airport10:50Prague AirportPrague Airport - T1/20EconomyA Flight from Brussels Airlines goes from Brussels Airport, Brussels Airport (Belgium) at 25/12/2025 09:25:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 25/12/2025 10:50:00. 50 Economy ticket for £174 per person are available. Travel duration is 1h 25m
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SAS Scandinavian Airlines4h 0m010:20Brussels AirportBrussels Airport14:20Prague AirportPrague Airport - T1/20EconomyA Flight from SAS Scandinavian Airlines goes from Brussels Airport, Brussels Airport (Belgium) at 25/12/2025 10:20:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 25/12/2025 14:20:00. 50 Economy ticket for £172 per person are available. Travel duration is 4h 0m
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Wizz Air11h 35m019:55Brussels South Charleroi AirportBrussels South Charleroi Airport07:30Prague AirportPrague Airport - T1/20EconomyA Flight from Wizz Air goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 25/12/2025 19:55:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 26/12/2025 07:30:00. 50 Economy ticket for £149 per person are available. Travel duration is 11h 35m
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LC Perú25h 5m021:00Brussels South Charleroi AirportBrussels South Charleroi Airport22:05Prague AirportPrague Airport - T1/20EconomyA Flight from LC Perú goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 25/12/2025 21:00:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 26/12/2025 22:05:00. 50 Economy ticket for £92 per person are available. Travel duration is 25h 5m
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FlixBus13h 35m010:30BrusselsNorth Station00:05PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 25/12/2025 10:30:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 26/12/2025 00:05:00. 50 Economy ticket for £61 per person are available. Travel duration is 13h 35m
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FlixBus13h 55m010:30BrusselsNorth Station00:25PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 25/12/2025 10:30:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 26/12/2025 00:25:00. 50 Economy ticket for £61 per person are available. Travel duration is 13h 55m
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FlixBus14h 40m016:15BrusselsMidi Bus Station06:55PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 25/12/2025 16:15:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 26/12/2025 06:55:00. 50 Economy ticket for £61 per person are available. Travel duration is 14h 40m
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FlixBus15h 0m022:10BrusselsMidi Bus Station13:10PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 25/12/2025 22:10:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 26/12/2025 13:10:00. 50 Economy ticket for £67 per person are available. Travel duration is 15h 0m
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FlixBus18h 35m016:15BrusselsMidi Bus Station10:50PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 25/12/2025 16:15:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 26/12/2025 10:50:00. 50 Economy ticket for £78 per person are available. Travel duration is 18h 35m
Fastest Flights Thursday
Fastest Buses Thursday
Here you will find all operators and timetables for a
Bus from Brussels to Prague
What are the most popular stations in Brussels and Prague?
In Brussels, you will usually depart from Midi Bus Station, North Station or Gare Centrale, while in Prague you will be arriving at Wilsonova Coach Station, ÚAN Florenc or Černý Most, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Prague from Brussels? With 8 connections between 2 Bus and Flight operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Brussels and Prague, you can pay as low as £57 with a Flight from Smartwings.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Ryanair: you will get to Prague in just 1h 25m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Brussels and Prague are FlixBus, Smartwings and Ryanair, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Brussels and Prague is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Saint-Gilles or to Horoměřice, and look at flights from Brussels South Charleroi Airport, and landing at Prague Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Brussels to Prague?
The most popular companies between Brussels and Prague, are FlixBus, Smartwings and Ryanair. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: FlixBus and European Sleeper
Airlines: Smartwings, Ryanair, Brussels Airlines and 11 more.
All you need to know when you travel from Brussels to Prague
Check all information on comfort and services on all modes of transports from Brussels to Prague. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Brussels to Prague
How can I reach Prague from Brussels?
Every day, there are on average 8 connections between Bus and Flight, with which you can get to Prague from Brussels.
How far is Prague from Brussels?
The distance between Brussels and Prague is 718.5 km.
What is the most ecofriendly mode of transport between Brussels and Prague?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 19 kgs of CO2, a train 25 kgs, a car 122 kgs, and a flight 177 kgs.
What is the cheapest mode of transport from Brussels to Prague?
You can get to Prague with just £57 by taking a Flight from Smartwings.
What is the fastest way to get from Brussels to Prague?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Prague in just 1h 25m with a Flight from Ryanair.
More routes to Brussels and to Prague
Looking for more options? Here you can see the most popular routes to Brussels and to Prague. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Brussels
- Amsterdam to Brussels
- Antwerp to Brussels
- Barcelona to Brussels
- Birmingham to Brussels
- Bologna to Brussels
- Bordeaux to Brussels
- Brussels Airport to Brussels
- Brussels South Charleroi Airport to Brussels
- Carcassonne to Brussels
- Dusseldorf to Brussels
- Glasgow to Brussels
- Lille to Brussels
- Linz to Brussels
- Lisbon to Brussels
- London to Brussels
- Lyon to Brussels
- Madrid to Brussels
- Munich to Brussels
- Nantes to Brussels
- Newcastle upon Tyne to Brussels
- Paris to Brussels
- The Hague to Brussels
- Toulouse to Brussels
- Zurich to Brussels
- Trips to Prague
- Amsterdam to Prague
- Bern to Prague
- Bologna to Prague
- Bratislava to Prague
- Česká Lípa to Prague
- Dortmund to Prague
- Hamburg to Prague
- Humpolec to Prague
- Jihlava to Prague
- Katowice to Prague
- Kosice to Prague
- Kysak to Prague
- Nuremberg to Prague
- Ostrava to Prague
- Paris to Prague
- Pilsen to Prague
- Prague Airport to Prague
- Presov to Prague
- St. Gallen to Prague
- Stuttgart to Prague
- Třebíč to Prague
- Warsaw Chopin Airport to Prague
- Warsaw to Prague
- Wroclaw to Prague
