What is the best way to travel from Lyon to Palermo?
Looking for a trip? Check and compare all the available Flights, Trains and Buses to Palermo from Lyon. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 2 available companies to find your perfect trip!
What is the cheapest way to reach Palermo from Lyon?
You can reach Palermo with just £45 by taking a Flight from Transavia France, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
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EasyJet Airline8h 5m013:40Lyons St. Exupery AirportAéroport St Exupéry Coach Station21:45Palermo AirportPalermo Airport0EconomyA Flight from EasyJet Airline goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 06/05/2026 13:40:00 to Palermo Airport, Palermo Airport (Italy) arriving at 06/05/2026 21:45:00. 50 Economy ticket for £79 per person are available. Travel duration is 8h 5m
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Vueling Airlines6h 40m016:05Lyons St. Exupery AirportAéroport St Exupéry Coach Station22:45Palermo AirportPalermo Airport0EconomyA Flight from Vueling Airlines goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 06/05/2026 16:05:00 to Palermo Airport, Palermo Airport (Italy) arriving at 06/05/2026 22:45:00. 50 Economy ticket for £100 per person are available. Travel duration is 6h 40m
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Turkish Airlines8h 10m010:25Lyons St. Exupery AirportAéroport St Exupéry Coach Station18:35Palermo AirportPalermo Airport0EconomyA Flight from Turkish Airlines goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 06/05/2026 10:25:00 to Palermo Airport, Palermo Airport (Italy) arriving at 06/05/2026 18:35:00. 50 Economy ticket for £213 per person are available. Travel duration is 8h 10m
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Air France18h 15m014:05Lyons St. Exupery AirportAéroport St Exupéry Coach Station08:20Palermo AirportPalermo Airport0EconomyA Flight from Air France goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 06/05/2026 14:05:00 to Palermo Airport, Palermo Airport (Italy) arriving at 07/05/2026 08:20:00. 50 Economy ticket for £230 per person are available. Travel duration is 18h 15m
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FlixBus31h 45m003:15LyonLyon Avenue Tony Garnier Coach Stop11:00PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 06/05/2026 03:15:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 07/05/2026 11:00:00. 50 Economy ticket for £96 per person are available. Travel duration is 31h 45m
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FlixBus33h 0m006:15LyonLyon Avenue Tony Garnier Coach Stop15:15PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 06/05/2026 06:15:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 07/05/2026 15:15:00. 50 Economy ticket for £101 per person are available. Travel duration is 33h 0m
Cheapest Flights Wednesday
Cheapest Buses Wednesday
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Vueling Airlines24h 15m022:35Lyons St. Exupery AirportAéroport St Exupéry Coach Station22:50Palermo AirportPalermo Airport0EconomyA Flight from Vueling Airlines goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 08/05/2026 22:35:00 to Palermo Airport, Palermo Airport (Italy) arriving at 09/05/2026 22:50:00. 50 Economy ticket for £81 per person are available. Travel duration is 24h 15m
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Volotea4h 30m020:15Lyons St. Exupery AirportAéroport St Exupéry Coach Station00:45Palermo AirportPalermo Airport0EconomyA Flight from Volotea goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 08/05/2026 20:15:00 to Palermo Airport, Palermo Airport (Italy) arriving at 09/05/2026 00:45:00. 50 Economy ticket for £94 per person are available. Travel duration is 4h 30m
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Transavia France2h 0m018:05Lyons St. Exupery AirportAéroport St Exupéry Coach Station20:05Palermo AirportPalermo Airport0EconomyA Flight from Transavia France goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 08/05/2026 18:05:00 to Palermo Airport, Palermo Airport (Italy) arriving at 08/05/2026 20:05:00. 50 Economy ticket for £134 per person are available. Travel duration is 2h 0m
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EasyJet Airline22h 5m019:05Lyons St. Exupery AirportLyons St. Exupery Airport17:10Palermo AirportPalermo Airport0EconomyA Flight from EasyJet Airline goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 08/05/2026 19:05:00 to Palermo Airport, Palermo Airport (Italy) arriving at 09/05/2026 17:10:00. 50 Economy ticket for £141 per person are available. Travel duration is 22h 5m
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FlixBus29h 40m009:35LyonLyon Avenue Tony Garnier Coach Stop15:15PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 08/05/2026 09:35:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 09/05/2026 15:15:00. 50 Economy ticket for £95 per person are available. Travel duration is 29h 40m
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FlixBus31h 45m003:15LyonLyon Avenue Tony Garnier Coach Stop11:00PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 08/05/2026 03:15:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 09/05/2026 11:00:00. 50 Economy ticket for £120 per person are available. Travel duration is 31h 45m
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FlixBus36h 0m023:00LyonLyon Avenue Tony Garnier Coach Stop11:00PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 08/05/2026 23:00:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 10/05/2026 11:00:00. 50 Economy ticket for £161 per person are available. Travel duration is 36h 0m
Cheapest Flights Friday
Cheapest Buses Friday
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Vueling Airlines9h 30m023:30Lyons St. Exupery AirportAéroport St Exupéry Coach Station09:00Palermo AirportPalermo Airport0EconomyA Flight from Vueling Airlines goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 09/05/2026 23:30:00 to Palermo Airport, Palermo Airport (Italy) arriving at 10/05/2026 09:00:00. 50 Economy ticket for £69 per person are available. Travel duration is 9h 30m
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Volotea20h 20m011:30Lyons St. Exupery AirportAéroport St Exupéry Coach Station07:50Palermo AirportPalermo Airport0EconomyA Flight from Volotea goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 09/05/2026 11:30:00 to Palermo Airport, Palermo Airport (Italy) arriving at 10/05/2026 07:50:00. 50 Economy ticket for £82 per person are available. Travel duration is 20h 20m
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Iberia9h 30m023:30Lyons St. Exupery AirportLyons St. Exupery Airport09:00Palermo AirportPalermo Airport0EconomyA Flight from Iberia goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 09/05/2026 23:30:00 to Palermo Airport, Palermo Airport (Italy) arriving at 10/05/2026 09:00:00. 50 Economy ticket for £107 per person are available. Travel duration is 9h 30m
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EasyJet Airline1h 55m011:00Lyons St. Exupery AirportLyons St. Exupery Airport12:55Palermo AirportPalermo Airport0EconomyA Flight from EasyJet Airline goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 09/05/2026 11:00:00 to Palermo Airport, Palermo Airport (Italy) arriving at 09/05/2026 12:55:00. 50 Economy ticket for £125 per person are available. Travel duration is 1h 55m
Cheapest Flights Saturday
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Vueling Airlines8h 25m023:20Lyons St. Exupery AirportAéroport St Exupéry Coach Station07:45Palermo AirportPalermo Airport0EconomyA Flight from Vueling Airlines goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 10/05/2026 23:20:00 to Palermo Airport, Palermo Airport (Italy) arriving at 11/05/2026 07:45:00. 50 Economy ticket for £63 per person are available. Travel duration is 8h 25m
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Volotea8h 40m015:00Lyons St. Exupery AirportAéroport St Exupéry Coach Station23:40Palermo AirportPalermo Airport0EconomyA Flight from Volotea goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 10/05/2026 15:00:00 to Palermo Airport, Palermo Airport (Italy) arriving at 10/05/2026 23:40:00. 50 Economy ticket for £73 per person are available. Travel duration is 8h 40m
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EasyJet Airline6h 0m017:40Lyons St. Exupery AirportAéroport St Exupéry Coach Station23:40Palermo AirportPalermo Airport0EconomyA Flight from EasyJet Airline goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 10/05/2026 17:40:00 to Palermo Airport, Palermo Airport (Italy) arriving at 10/05/2026 23:40:00. 50 Economy ticket for £89 per person are available. Travel duration is 6h 0m
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Air France9h 50m006:00Lyons St. Exupery AirportAéroport St Exupéry Coach Station15:50Palermo AirportPalermo Airport0EconomyA Flight from Air France goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 10/05/2026 06:00:00 to Palermo Airport, Palermo Airport (Italy) arriving at 10/05/2026 15:50:00. 50 Economy ticket for £163 per person are available. Travel duration is 9h 50m
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FlixBus31h 45m003:15LyonLyon Avenue Tony Garnier Coach Stop11:00PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 10/05/2026 03:15:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 11/05/2026 11:00:00. 50 Economy ticket for £79 per person are available. Travel duration is 31h 45m
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FlixBus36h 0m023:00LyonLyon Avenue Tony Garnier Coach Stop11:00PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 10/05/2026 23:00:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 12/05/2026 11:00:00. 50 Economy ticket for £84 per person are available. Travel duration is 36h 0m
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FlixBus29h 40m009:35LyonLyon Avenue Tony Garnier Coach Stop15:15PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 10/05/2026 09:35:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 11/05/2026 15:15:00. 50 Economy ticket for £97 per person are available. Travel duration is 29h 40m
Cheapest Flights Sunday
Cheapest Buses Sunday
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Transavia France2h 0m006:00Lyons St. Exupery AirportAéroport St Exupéry Coach Station08:00Palermo AirportPalermo Airport0EconomyA Flight from Transavia France goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 11/05/2026 06:00:00 to Palermo Airport, Palermo Airport (Italy) arriving at 11/05/2026 08:00:00. 50 Economy ticket for £45 per person are available. Travel duration is 2h 0m
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EasyJet Airline1h 55m010:20Lyons St. Exupery AirportAéroport St Exupéry Coach Station12:15Palermo AirportPalermo Airport0EconomyA Flight from EasyJet Airline goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 11/05/2026 10:20:00 to Palermo Airport, Palermo Airport (Italy) arriving at 11/05/2026 12:15:00. 50 Economy ticket for £71 per person are available. Travel duration is 1h 55m
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Skyscanner1h 55m010:20Lyons St. Exupery AirportAéroport St Exupéry Coach Station12:15Palermo AirportPalermo Airport0EconomyA Flight from Skyscanner goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 11/05/2026 10:20:00 to Palermo Airport, Palermo Airport (Italy) arriving at 11/05/2026 12:15:00. 50 Economy ticket for £73 per person are available. Travel duration is 1h 55m
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Volotea10h 30m009:40Lyons St. Exupery AirportAéroport St Exupéry Coach Station20:10Palermo AirportPalermo Airport0EconomyA Flight from Volotea goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 11/05/2026 09:40:00 to Palermo Airport, Palermo Airport (Italy) arriving at 11/05/2026 20:10:00. 50 Economy ticket for £74 per person are available. Travel duration is 10h 30m
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FlixBus31h 45m003:15LyonLyon Avenue Tony Garnier Coach Stop11:00PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 11/05/2026 03:15:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 12/05/2026 11:00:00. 50 Economy ticket for £86 per person are available. Travel duration is 31h 45m
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FlixBus29h 40m009:35LyonLyon Avenue Tony Garnier Coach Stop15:15PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 11/05/2026 09:35:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 12/05/2026 15:15:00. 50 Economy ticket for £87 per person are available. Travel duration is 29h 40m
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FlixBus36h 0m023:00LyonLyon Avenue Tony Garnier Coach Stop11:00PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 11/05/2026 23:00:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 13/05/2026 11:00:00. 50 Economy ticket for £103 per person are available. Travel duration is 36h 0m
Cheapest Flights Monday
Cheapest Buses Monday
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Volotea11h 30m021:10Lyons St. Exupery AirportAéroport St Exupéry Coach Station08:40Palermo AirportPalermo Airport0EconomyA Flight from Volotea goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 12/05/2026 21:10:00 to Palermo Airport, Palermo Airport (Italy) arriving at 13/05/2026 08:40:00. 50 Economy ticket for £48 per person are available. Travel duration is 11h 30m
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EasyJet Airline14h 15m006:55Lyons St. Exupery AirportAéroport St Exupéry Coach Station21:10Palermo AirportPalermo Airport0EconomyA Flight from EasyJet Airline goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 12/05/2026 06:55:00 to Palermo Airport, Palermo Airport (Italy) arriving at 12/05/2026 21:10:00. 50 Economy ticket for £100 per person are available. Travel duration is 14h 15m
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Vueling Airlines9h 0m013:55Lyons St. Exupery AirportAéroport St Exupéry Coach Station22:55Palermo AirportPalermo Airport0EconomyA Flight from Vueling Airlines goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 12/05/2026 13:55:00 to Palermo Airport, Palermo Airport (Italy) arriving at 12/05/2026 22:55:00. 50 Economy ticket for £115 per person are available. Travel duration is 9h 0m
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Lufthansa CityLine7h 55m009:25Lyons St. Exupery AirportAéroport St Exupéry Coach Station17:20Palermo AirportPalermo Airport0EconomyA Flight from Lufthansa CityLine goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 12/05/2026 09:25:00 to Palermo Airport, Palermo Airport (Italy) arriving at 12/05/2026 17:20:00. 50 Economy ticket for £215 per person are available. Travel duration is 7h 55m
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FlixBus31h 45m003:15LyonLyon Avenue Tony Garnier Coach Stop11:00PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 12/05/2026 03:15:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 13/05/2026 11:00:00. 50 Economy ticket for £89 per person are available. Travel duration is 31h 45m
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FlixBus29h 40m009:35LyonLyon Avenue Tony Garnier Coach Stop15:15PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 12/05/2026 09:35:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 13/05/2026 15:15:00. 50 Economy ticket for £90 per person are available. Travel duration is 29h 40m
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FlixBus36h 0m023:00LyonLyon Avenue Tony Garnier Coach Stop11:00PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 12/05/2026 23:00:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 14/05/2026 11:00:00. 50 Economy ticket for £109 per person are available. Travel duration is 36h 0m
Cheapest Flights Tuesday
Cheapest Buses Tuesday
What are the fastest trips from Lyon to Palermo?
You can get to Palermo from Lyon in just 1h 55m with a Flight from EasyJet Airline. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
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Vueling Airlines6h 40m016:05Lyons St. Exupery AirportAéroport St Exupéry Coach Station22:45Palermo AirportPalermo Airport0EconomyA Flight from Vueling Airlines goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 06/05/2026 16:05:00 to Palermo Airport, Palermo Airport (Italy) arriving at 06/05/2026 22:45:00. 50 Economy ticket for £100 per person are available. Travel duration is 6h 40m
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EasyJet Airline8h 5m013:40Lyons St. Exupery AirportAéroport St Exupéry Coach Station21:45Palermo AirportPalermo Airport0EconomyA Flight from EasyJet Airline goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 06/05/2026 13:40:00 to Palermo Airport, Palermo Airport (Italy) arriving at 06/05/2026 21:45:00. 50 Economy ticket for £79 per person are available. Travel duration is 8h 5m
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Turkish Airlines8h 10m010:25Lyons St. Exupery AirportAéroport St Exupéry Coach Station18:35Palermo AirportPalermo Airport0EconomyA Flight from Turkish Airlines goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 06/05/2026 10:25:00 to Palermo Airport, Palermo Airport (Italy) arriving at 06/05/2026 18:35:00. 50 Economy ticket for £213 per person are available. Travel duration is 8h 10m
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Air France18h 15m014:05Lyons St. Exupery AirportAéroport St Exupéry Coach Station08:20Palermo AirportPalermo Airport0EconomyA Flight from Air France goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 06/05/2026 14:05:00 to Palermo Airport, Palermo Airport (Italy) arriving at 07/05/2026 08:20:00. 50 Economy ticket for £230 per person are available. Travel duration is 18h 15m
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FlixBus31h 45m003:15LyonLyon Avenue Tony Garnier Coach Stop11:00PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 06/05/2026 03:15:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 07/05/2026 11:00:00. 50 Economy ticket for £96 per person are available. Travel duration is 31h 45m
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FlixBus33h 0m006:15LyonLyon Avenue Tony Garnier Coach Stop15:15PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 06/05/2026 06:15:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 07/05/2026 15:15:00. 50 Economy ticket for £101 per person are available. Travel duration is 33h 0m
Fastest Flights Wednesday
Fastest Buses Wednesday
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Transavia France2h 0m018:05Lyons St. Exupery AirportAéroport St Exupéry Coach Station20:05Palermo AirportPalermo Airport0EconomyA Flight from Transavia France goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 08/05/2026 18:05:00 to Palermo Airport, Palermo Airport (Italy) arriving at 08/05/2026 20:05:00. 50 Economy ticket for £134 per person are available. Travel duration is 2h 0m
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Enter Air2h 10m015:45Lyons St. Exupery AirportLyons St. Exupery Airport17:55Palermo AirportPalermo Airport0EconomyA Flight from Enter Air goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 08/05/2026 15:45:00 to Palermo Airport, Palermo Airport (Italy) arriving at 08/05/2026 17:55:00. 50 Economy ticket for £141 per person are available. Travel duration is 2h 10m
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Volotea4h 30m020:15Lyons St. Exupery AirportAéroport St Exupéry Coach Station00:45Palermo AirportPalermo Airport0EconomyA Flight from Volotea goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 08/05/2026 20:15:00 to Palermo Airport, Palermo Airport (Italy) arriving at 09/05/2026 00:45:00. 50 Economy ticket for £94 per person are available. Travel duration is 4h 30m
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EasyJet Airline22h 5m019:05Lyons St. Exupery AirportLyons St. Exupery Airport17:10Palermo AirportPalermo Airport0EconomyA Flight from EasyJet Airline goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 08/05/2026 19:05:00 to Palermo Airport, Palermo Airport (Italy) arriving at 09/05/2026 17:10:00. 50 Economy ticket for £141 per person are available. Travel duration is 22h 5m
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FlixBus29h 40m009:35LyonLyon Avenue Tony Garnier Coach Stop15:15PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 08/05/2026 09:35:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 09/05/2026 15:15:00. 50 Economy ticket for £95 per person are available. Travel duration is 29h 40m
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FlixBus31h 45m003:15LyonLyon Avenue Tony Garnier Coach Stop11:00PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 08/05/2026 03:15:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 09/05/2026 11:00:00. 50 Economy ticket for £120 per person are available. Travel duration is 31h 45m
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FlixBus36h 0m023:00LyonLyon Avenue Tony Garnier Coach Stop11:00PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 08/05/2026 23:00:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 10/05/2026 11:00:00. 50 Economy ticket for £161 per person are available. Travel duration is 36h 0m
Fastest Flights Friday
Fastest Buses Friday
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EasyJet Airline1h 55m011:00Lyons St. Exupery AirportLyons St. Exupery Airport12:55Palermo AirportPalermo Airport0EconomyA Flight from EasyJet Airline goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 09/05/2026 11:00:00 to Palermo Airport, Palermo Airport (Italy) arriving at 09/05/2026 12:55:00. 50 Economy ticket for £125 per person are available. Travel duration is 1h 55m
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Skyscanner1h 55m011:00Lyons St. Exupery AirportAéroport St Exupéry Coach Station12:55Palermo AirportPalermo Airport0EconomyA Flight from Skyscanner goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 09/05/2026 11:00:00 to Palermo Airport, Palermo Airport (Italy) arriving at 09/05/2026 12:55:00. 50 Economy ticket for £132 per person are available. Travel duration is 1h 55m
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Vueling Airlines9h 30m023:30Lyons St. Exupery AirportAéroport St Exupéry Coach Station09:00Palermo AirportPalermo Airport0EconomyA Flight from Vueling Airlines goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 09/05/2026 23:30:00 to Palermo Airport, Palermo Airport (Italy) arriving at 10/05/2026 09:00:00. 50 Economy ticket for £69 per person are available. Travel duration is 9h 30m
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Iberia9h 30m023:30Lyons St. Exupery AirportLyons St. Exupery Airport09:00Palermo AirportPalermo Airport0EconomyA Flight from Iberia goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 09/05/2026 23:30:00 to Palermo Airport, Palermo Airport (Italy) arriving at 10/05/2026 09:00:00. 50 Economy ticket for £107 per person are available. Travel duration is 9h 30m
Fastest Flights Saturday
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EasyJet Airline6h 0m017:40Lyons St. Exupery AirportAéroport St Exupéry Coach Station23:40Palermo AirportPalermo Airport0EconomyA Flight from EasyJet Airline goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 10/05/2026 17:40:00 to Palermo Airport, Palermo Airport (Italy) arriving at 10/05/2026 23:40:00. 50 Economy ticket for £89 per person are available. Travel duration is 6h 0m
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Hop!6h 50m009:00Lyons St. Exupery AirportAéroport St Exupéry Coach Station15:50Palermo AirportPalermo Airport0EconomyA Flight from Hop! goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 10/05/2026 09:00:00 to Palermo Airport, Palermo Airport (Italy) arriving at 10/05/2026 15:50:00. 50 Economy ticket for £171 per person are available. Travel duration is 6h 50m
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Vueling Airlines8h 25m023:20Lyons St. Exupery AirportAéroport St Exupéry Coach Station07:45Palermo AirportPalermo Airport0EconomyA Flight from Vueling Airlines goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 10/05/2026 23:20:00 to Palermo Airport, Palermo Airport (Italy) arriving at 11/05/2026 07:45:00. 50 Economy ticket for £63 per person are available. Travel duration is 8h 25m
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Volotea8h 40m015:00Lyons St. Exupery AirportAéroport St Exupéry Coach Station23:40Palermo AirportPalermo Airport0EconomyA Flight from Volotea goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 10/05/2026 15:00:00 to Palermo Airport, Palermo Airport (Italy) arriving at 10/05/2026 23:40:00. 50 Economy ticket for £73 per person are available. Travel duration is 8h 40m
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FlixBus29h 40m009:35LyonLyon Avenue Tony Garnier Coach Stop15:15PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 10/05/2026 09:35:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 11/05/2026 15:15:00. 50 Economy ticket for £97 per person are available. Travel duration is 29h 40m
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FlixBus31h 45m003:15LyonLyon Avenue Tony Garnier Coach Stop11:00PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 10/05/2026 03:15:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 11/05/2026 11:00:00. 50 Economy ticket for £79 per person are available. Travel duration is 31h 45m
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FlixBus36h 0m023:00LyonLyon Avenue Tony Garnier Coach Stop11:00PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 10/05/2026 23:00:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 12/05/2026 11:00:00. 50 Economy ticket for £84 per person are available. Travel duration is 36h 0m
Fastest Flights Sunday
Fastest Buses Sunday
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EasyJet Airline1h 55m010:20Lyons St. Exupery AirportAéroport St Exupéry Coach Station12:15Palermo AirportPalermo Airport0EconomyA Flight from EasyJet Airline goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 11/05/2026 10:20:00 to Palermo Airport, Palermo Airport (Italy) arriving at 11/05/2026 12:15:00. 50 Economy ticket for £71 per person are available. Travel duration is 1h 55m
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Skyscanner1h 55m010:20Lyons St. Exupery AirportAéroport St Exupéry Coach Station12:15Palermo AirportPalermo Airport0EconomyA Flight from Skyscanner goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 11/05/2026 10:20:00 to Palermo Airport, Palermo Airport (Italy) arriving at 11/05/2026 12:15:00. 50 Economy ticket for £73 per person are available. Travel duration is 1h 55m
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Transavia France2h 0m006:00Lyons St. Exupery AirportAéroport St Exupéry Coach Station08:00Palermo AirportPalermo Airport0EconomyA Flight from Transavia France goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 11/05/2026 06:00:00 to Palermo Airport, Palermo Airport (Italy) arriving at 11/05/2026 08:00:00. 50 Economy ticket for £45 per person are available. Travel duration is 2h 0m
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Hop!5h 5m012:35Lyons St. Exupery AirportAéroport St Exupéry Coach Station17:40Palermo AirportPalermo Airport0EconomyA Flight from Hop! goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 11/05/2026 12:35:00 to Palermo Airport, Palermo Airport (Italy) arriving at 11/05/2026 17:40:00. 50 Economy ticket for £138 per person are available. Travel duration is 5h 5m
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FlixBus29h 40m009:35LyonLyon Avenue Tony Garnier Coach Stop15:15PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 11/05/2026 09:35:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 12/05/2026 15:15:00. 50 Economy ticket for £87 per person are available. Travel duration is 29h 40m
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FlixBus31h 45m003:15LyonLyon Avenue Tony Garnier Coach Stop11:00PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 11/05/2026 03:15:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 12/05/2026 11:00:00. 50 Economy ticket for £86 per person are available. Travel duration is 31h 45m
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FlixBus36h 0m023:00LyonLyon Avenue Tony Garnier Coach Stop11:00PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 11/05/2026 23:00:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 13/05/2026 11:00:00. 50 Economy ticket for £103 per person are available. Travel duration is 36h 0m
Fastest Flights Monday
Fastest Buses Monday
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Lufthansa4h 20m013:00Lyons St. Exupery AirportLyons St. Exupery Airport17:20Palermo AirportPalermo Airport0EconomyA Flight from Lufthansa goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 12/05/2026 13:00:00 to Palermo Airport, Palermo Airport (Italy) arriving at 12/05/2026 17:20:00. 50 Economy ticket for £215 per person are available. Travel duration is 4h 20m
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Lufthansa CityLine7h 55m009:25Lyons St. Exupery AirportAéroport St Exupéry Coach Station17:20Palermo AirportPalermo Airport0EconomyA Flight from Lufthansa CityLine goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 12/05/2026 09:25:00 to Palermo Airport, Palermo Airport (Italy) arriving at 12/05/2026 17:20:00. 50 Economy ticket for £215 per person are available. Travel duration is 7h 55m
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Vueling Airlines9h 0m013:55Lyons St. Exupery AirportAéroport St Exupéry Coach Station22:55Palermo AirportPalermo Airport0EconomyA Flight from Vueling Airlines goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 12/05/2026 13:55:00 to Palermo Airport, Palermo Airport (Italy) arriving at 12/05/2026 22:55:00. 50 Economy ticket for £115 per person are available. Travel duration is 9h 0m
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Volotea11h 30m021:10Lyons St. Exupery AirportAéroport St Exupéry Coach Station08:40Palermo AirportPalermo Airport0EconomyA Flight from Volotea goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 12/05/2026 21:10:00 to Palermo Airport, Palermo Airport (Italy) arriving at 13/05/2026 08:40:00. 50 Economy ticket for £48 per person are available. Travel duration is 11h 30m
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FlixBus29h 40m009:35LyonLyon Avenue Tony Garnier Coach Stop15:15PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 12/05/2026 09:35:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 13/05/2026 15:15:00. 50 Economy ticket for £90 per person are available. Travel duration is 29h 40m
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FlixBus31h 45m003:15LyonLyon Avenue Tony Garnier Coach Stop11:00PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 12/05/2026 03:15:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 13/05/2026 11:00:00. 50 Economy ticket for £89 per person are available. Travel duration is 31h 45m
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FlixBus36h 0m023:00LyonLyon Avenue Tony Garnier Coach Stop11:00PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 12/05/2026 23:00:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 14/05/2026 11:00:00. 50 Economy ticket for £109 per person are available. Travel duration is 36h 0m
Fastest Flights Tuesday
Fastest Buses Tuesday
Here you will find all operators and timetables for a
Bus from Lyon to Palermo
What are the most popular stations in Lyon and Palermo?
In Lyon, you will usually depart from Part-Dieu Train Station, Perrache Train Station or Perrache Bus Stop, while in Palermo you will be arriving at Via Fazello, Via Belgio or Cinisi Via Nazionale Coach Stop, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Palermo from Lyon? With 7 connections between 2 Train, Flight and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Lyon and Palermo, you can pay as low as £45 with a Flight from Transavia France.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from EasyJet Airline: you will get to Palermo in just 1h 55m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Lyon and Palermo are FlixBus, EasyJet Airline and Vueling Airlines, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Lyon and Palermo is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Caluire-et-Cuire or to Ciaculli, and look at flights from Lyons St. Exupery Airport, and landing at Palermo Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Lyon to Palermo?
The most popular companies between Lyon and Palermo, are FlixBus, EasyJet Airline and Vueling Airlines. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: FlixBus
Airlines: EasyJet Airline, Vueling Airlines, Volotea and 10 more.
All you need to know when you travel from Lyon to Palermo
Check all information on comfort and services on all modes of transports from Lyon to Palermo. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Lyon to Palermo
How can I reach Palermo from Lyon?
Every day, there are on average 7 connections between Train, Flight and Bus, with which you can get to Palermo from Lyon.
How far is Palermo from Lyon?
The distance between Lyon and Palermo is 1,103.0 km.
What is the most ecofriendly mode of transport between Lyon and Palermo?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 30 kgs of CO2, a train 39 kgs, a car 188 kgs, and a flight 271 kgs.
What is the cheapest mode of transport from Lyon to Palermo?
You can get to Palermo with just £45 by taking a Flight from Transavia France.
What is the fastest way to get from Lyon to Palermo?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Palermo in just 1h 55m with a Flight from EasyJet Airline.
More routes to Lyon and to Palermo
Looking for more options? Here you can see the most popular routes to Lyon and to Palermo. Simply click on a connection, and you’ll find all the details about the route!
