What is the best way to travel from Lyon to Palermo?
Looking for a trip? Check and compare all the available Buses and Carpool to Palermo from Lyon. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 1 available companies to find your perfect trip!
What is the cheapest way to reach Palermo from Lyon?
You can reach Palermo with just £77 by taking a Bus from FlixBus, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
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FlixBus31h 35m003:25LyonLyon Avenue Tony Garnier Coach Stop11:00PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 25/03/2026 03:25:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 26/03/2026 11:00:00. 50 Economy ticket for £77 per person are available. Travel duration is 31h 35m
Cheapest Buses Wednesday
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FlixBus31h 35m003:25LyonLyon Avenue Tony Garnier Coach Stop11:00PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 27/03/2026 03:25:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 28/03/2026 11:00:00. 50 Economy ticket for £84 per person are available. Travel duration is 31h 35m
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FlixBus28h 20m009:35LyonLyon Avenue Tony Garnier Coach Stop13:55PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 27/03/2026 09:35:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 28/03/2026 13:55:00. 50 Economy ticket for £89 per person are available. Travel duration is 28h 20m
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FlixBus36h 0m023:00LyonLyon Avenue Tony Garnier Coach Stop12:00PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 27/03/2026 23:00:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 29/03/2026 12:00:00. 50 Economy ticket for £104 per person are available. Travel duration is 36h 0m
Cheapest Buses Friday
What are the fastest trips from Lyon to Palermo?
You can get to Palermo from Lyon in just 28h 20m with a Bus from FlixBus. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
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FlixBus31h 35m003:25LyonLyon Avenue Tony Garnier Coach Stop11:00PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 25/03/2026 03:25:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 26/03/2026 11:00:00. 50 Economy ticket for £77 per person are available. Travel duration is 31h 35m
Fastest Buses Wednesday
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FlixBus28h 20m009:35LyonLyon Avenue Tony Garnier Coach Stop13:55PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 27/03/2026 09:35:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 28/03/2026 13:55:00. 50 Economy ticket for £89 per person are available. Travel duration is 28h 20m
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FlixBus31h 35m003:25LyonLyon Avenue Tony Garnier Coach Stop11:00PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 27/03/2026 03:25:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 28/03/2026 11:00:00. 50 Economy ticket for £84 per person are available. Travel duration is 31h 35m
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FlixBus36h 0m023:00LyonLyon Avenue Tony Garnier Coach Stop12:00PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 27/03/2026 23:00:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 29/03/2026 12:00:00. 50 Economy ticket for £104 per person are available. Travel duration is 36h 0m
Fastest Buses Friday
Here you will find all operators and timetables for a
Bus from Lyon to Palermo
What are the most popular stations in Lyon and Palermo?
In Lyon, you will usually depart from Perrache Bus Stop, Perrache Train Station or Part-Dieu Train Station, while in Palermo you will be arriving at Cinisi Via Nazionale Coach Stop, Via Belgio or Via Fazello, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Palermo from Lyon? With 2 connections between 1 Bus and Carpool operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Lyon and Palermo, you can pay as low as £77 with a Bus from FlixBus.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Bus from FlixBus: you will get to Palermo in just 28h 20m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Lyon and Palermo are FlixBus, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Lyon and Palermo is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Caluire-et-Cuire or to Ciaculli, and look at flights from Lyons St. Exupery Airport, and landing at Palermo Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Lyon to Palermo?
The most popular companies between Lyon and Palermo, are FlixBus. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: FlixBus
All you need to know when you travel from Lyon to Palermo
Check all information on comfort and services on all modes of transports from Lyon to Palermo. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Lyon to Palermo
How can I reach Palermo from Lyon?
Every day, there are on average 2 connections between Bus and Carpool, with which you can get to Palermo from Lyon.
How far is Palermo from Lyon?
The distance between Lyon and Palermo is 1,103.0 km.
What is the most ecofriendly mode of transport between Lyon and Palermo?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 30 kgs of CO2, a train 39 kgs, a car 188 kgs, and a flight 271 kgs.
What is the cheapest mode of transport from Lyon to Palermo?
You can get to Palermo with just £77 by taking a Bus from FlixBus.
What is the fastest way to get from Lyon to Palermo?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Palermo in just 28h 20m with a Bus from FlixBus.
More routes to Lyon and to Palermo
Looking for more options? Here you can see the most popular routes to Lyon and to Palermo. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Lyon
- Alicante to Lyon
- Annecy to Lyon
- Barcelona to Lyon
- Basel to Lyon
- Béziers to Lyon
- Bologna to Lyon
- Bordeaux to Lyon
- Chambery to Lyon
- Dijon to Lyon
- Dusseldorf to Lyon
- Geneva to Lyon
- Genoa to Lyon
- Grenoble to Lyon
- London to Lyon
- Marseille to Lyon
- Milan to Lyon
- Nancy to Lyon
- Nice to Lyon
- Paris to Lyon
- Rome to Lyon
- Strasbourg to Lyon
- Toulouse to Lyon
- Turin to Lyon
- Valencia to Lyon
- Trips to Palermo
- Agrigento to Palermo
- Bari to Palermo
- Bologna to Palermo
- Caltanissetta to Palermo
- Catania to Palermo
- Catania-Fontanarossa Airport to Palermo
- Cefalù to Palermo
- Florence to Palermo
- Gela to Palermo
- Lecce to Palermo
- Marsala to Palermo
- Mazara del Vallo to Palermo
- Messina to Palermo
- Milan to Palermo
- Milazzo to Palermo
- Naples to Palermo
- Palermo Airport to Palermo
- Ragusa to Palermo
- Rome to Palermo
- Siracusa to Palermo
- Trapani Airport to Palermo
- Trapani to Palermo
- Turin to Palermo
- Vittoria to Palermo
