What is the best way to travel from Frankfurt am Main to Lyon?
Looking for a trip? Check and compare all the available Flights, Buses and Trains to Lyon from Frankfurt am Main. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 4 available companies to find your perfect trip!
What is the cheapest way to reach Lyon from Frankfurt am Main?
You can reach Lyon with just £27 by taking a Bus from BlaBlaCar Bus, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
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FlixBus11h 55m011:20Frankfurt am MainCentral Station23:15LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 05/05/2026 11:20:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 05/05/2026 23:15:00. 50 Economy ticket for £38 per person are available. Travel duration is 11h 55m
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FlixBus9h 40m019:05Frankfurt am MainCentral Station04:45LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 05/05/2026 19:05:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 06/05/2026 04:45:00. 50 Economy ticket for £40 per person are available. Travel duration is 9h 40m
Cheapest Buses Tuesday
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BlaBlaCar Bus11h 50m008:55Frankfurt am MainCentral Coach Station20:45LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Central Coach Station, Frankfurt am Main (Germany) at 06/05/2026 08:55:00 to Perrache Train Station, Lyon (France) arriving at 06/05/2026 20:45:00. 50 Economy ticket for £35 per person are available. Travel duration is 11h 50m
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FlixBus12h 35m008:15Frankfurt am MainCentral Station20:50LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 06/05/2026 08:15:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 06/05/2026 20:50:00. 50 Economy ticket for £39 per person are available. Travel duration is 12h 35m
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FlixBus9h 40m019:05Frankfurt am MainCentral Station04:45LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 06/05/2026 19:05:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 07/05/2026 04:45:00. 50 Economy ticket for £40 per person are available. Travel duration is 9h 40m
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FlixBus11h 55m011:20Frankfurt am MainCentral Station23:15LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 06/05/2026 11:20:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 06/05/2026 23:15:00. 50 Economy ticket for £50 per person are available. Travel duration is 11h 55m
Cheapest Buses Wednesday
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FlixBus12h 35m008:15Frankfurt am MainCentral Station20:50LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 07/05/2026 08:15:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 07/05/2026 20:50:00. 50 Economy ticket for £40 per person are available. Travel duration is 12h 35m
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FlixBus11h 55m011:20Frankfurt am MainCentral Station23:15LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 07/05/2026 11:20:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 07/05/2026 23:15:00. 50 Economy ticket for £46 per person are available. Travel duration is 11h 55m
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FlixBus13h 5m015:30Frankfurt am MainCentral Station04:35LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 07/05/2026 15:30:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 08/05/2026 04:35:00. 50 Economy ticket for £46 per person are available. Travel duration is 13h 5m
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FlixBus11h 45m022:45Frankfurt am MainCentral Station10:30LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 07/05/2026 22:45:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 08/05/2026 10:30:00. 50 Economy ticket for £47 per person are available. Travel duration is 11h 45m
Cheapest Buses Thursday
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BlaBlaCar Bus10h 40m018:30Frankfurt am MainCentral Coach Station05:10LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Central Coach Station, Frankfurt am Main (Germany) at 08/05/2026 18:30:00 to Perrache Train Station, Lyon (France) arriving at 09/05/2026 05:10:00. 50 Economy ticket for £30 per person are available. Travel duration is 10h 40m
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BlaBlaCar Bus11h 50m008:55Frankfurt am MainCentral Coach Station20:45LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Central Coach Station, Frankfurt am Main (Germany) at 08/05/2026 08:55:00 to Perrache Train Station, Lyon (France) arriving at 08/05/2026 20:45:00. 50 Economy ticket for £35 per person are available. Travel duration is 11h 50m
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FlixBus9h 40m019:05Frankfurt am MainCentral Station04:45LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 08/05/2026 19:05:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 09/05/2026 04:45:00. 50 Economy ticket for £40 per person are available. Travel duration is 9h 40m
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FlixBus12h 35m008:15Frankfurt am MainCentral Station20:50LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 08/05/2026 08:15:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 08/05/2026 20:50:00. 50 Economy ticket for £43 per person are available. Travel duration is 12h 35m
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TGV Lyria5h 56m014:02Frankfurt am MainCentral Station19:58LyonPart-Dieu Train Station0EconomyA Train from TGV Lyria goes from Central Station, Frankfurt am Main (Germany) at 08/05/2026 14:02:00 to Part-Dieu Train Station, Lyon (France) arriving at 08/05/2026 19:58:00. 50 Economy ticket for £78 per person are available. Travel duration is 5h 56m
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TGV Lyria7h 1m012:53Frankfurt am MainCentral Station19:54LyonPart-Dieu Train Station0EconomyA Train from TGV Lyria goes from Central Station, Frankfurt am Main (Germany) at 08/05/2026 12:53:00 to Part-Dieu Train Station, Lyon (France) arriving at 08/05/2026 19:54:00. 50 Economy ticket for £150 per person are available. Travel duration is 7h 1m
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Air Dolomiti1h 20m008:40Frankfurt am Main AirportFrankfurt am Main Airport10:00Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Air Dolomiti goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 08/05/2026 08:40:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 08/05/2026 10:00:00. 50 Economy ticket for £166 per person are available. Travel duration is 1h 20m
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Lufthansa1h 20m016:50Frankfurt am Main AirportFrankfurt am Main Airport18:10Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 08/05/2026 16:50:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 08/05/2026 18:10:00. 50 Economy ticket for £166 per person are available. Travel duration is 1h 20m
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Lufthansa1h 20m008:40Frankfurt am Main AirportFrankfurt am Main Airport10:00Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 08/05/2026 08:40:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 08/05/2026 10:00:00. 50 Economy ticket for £166 per person are available. Travel duration is 1h 20m
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Lufthansa1h 20m012:35Frankfurt am Main AirportFrankfurt am Main Airport13:55Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 08/05/2026 12:35:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 08/05/2026 13:55:00. 50 Economy ticket for £166 per person are available. Travel duration is 1h 20m
Cheapest Buses Friday
Cheapest Trains Friday
Cheapest Flights Friday
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BlaBlaCar Bus10h 40m018:30Frankfurt am MainCentral Coach Station05:10LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Central Coach Station, Frankfurt am Main (Germany) at 09/05/2026 18:30:00 to Perrache Train Station, Lyon (France) arriving at 10/05/2026 05:10:00. 50 Economy ticket for £27 per person are available. Travel duration is 10h 40m
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FlixBus9h 35m019:30Frankfurt am Main AirportFrankfurt am Main Airport05:05LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 09/05/2026 19:30:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 10/05/2026 05:05:00. 50 Economy ticket for £39 per person are available. Travel duration is 9h 35m
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FlixBus11h 25m023:05Frankfurt am Main AirportFrankfurt am Main Airport10:30LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 09/05/2026 23:05:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 10/05/2026 10:30:00. 50 Economy ticket for £40 per person are available. Travel duration is 11h 25m
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FlixBus11h 45m022:45Frankfurt am MainCentral Station10:30LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 09/05/2026 22:45:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 10/05/2026 10:30:00. 50 Economy ticket for £40 per person are available. Travel duration is 11h 45m
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Lufthansa1h 20m012:00Frankfurt am Main AirportFrankfurt am Main Airport13:20Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 09/05/2026 12:00:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 09/05/2026 13:20:00. 50 Economy ticket for £150 per person are available. Travel duration is 1h 20m
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Air Dolomiti1h 20m008:30Frankfurt am Main AirportFrankfurt am Main Airport09:50Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Air Dolomiti goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 09/05/2026 08:30:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 09/05/2026 09:50:00. 50 Economy ticket for £163 per person are available. Travel duration is 1h 20m
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Lufthansa1h 20m008:30Frankfurt am Main AirportFrankfurt am Main Airport09:50Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 09/05/2026 08:30:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 09/05/2026 09:50:00. 50 Economy ticket for £166 per person are available. Travel duration is 1h 20m
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Lufthansa1h 20m016:50Frankfurt am Main AirportFrankfurt am Main Airport18:10Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 09/05/2026 16:50:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 09/05/2026 18:10:00. 50 Economy ticket for £188 per person are available. Travel duration is 1h 20m
Cheapest Buses Saturday
Cheapest Flights Saturday
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BlaBlaCar Bus10h 40m018:30Frankfurt am MainCentral Coach Station05:10LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Central Coach Station, Frankfurt am Main (Germany) at 10/05/2026 18:30:00 to Perrache Train Station, Lyon (France) arriving at 11/05/2026 05:10:00. 50 Economy ticket for £30 per person are available. Travel duration is 10h 40m
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FlixBus9h 35m019:30Frankfurt am Main AirportFrankfurt am Main Airport05:05LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 10/05/2026 19:30:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 11/05/2026 05:05:00. 50 Economy ticket for £41 per person are available. Travel duration is 9h 35m
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FlixBus11h 25m023:05Frankfurt am Main AirportFrankfurt am Main Airport10:30LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 10/05/2026 23:05:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 11/05/2026 10:30:00. 50 Economy ticket for £43 per person are available. Travel duration is 11h 25m
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FlixBus11h 45m022:45Frankfurt am MainCentral Station10:30LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 10/05/2026 22:45:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 11/05/2026 10:30:00. 50 Economy ticket for £43 per person are available. Travel duration is 11h 45m
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Lufthansa1h 20m008:20Frankfurt am Main AirportFrankfurt am Main Airport09:40Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 10/05/2026 08:20:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 10/05/2026 09:40:00. 50 Economy ticket for £163 per person are available. Travel duration is 1h 20m
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Air Dolomiti1h 20m008:20Frankfurt am Main AirportFrankfurt am Main Airport09:40Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Air Dolomiti goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 10/05/2026 08:20:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 10/05/2026 09:40:00. 50 Economy ticket for £164 per person are available. Travel duration is 1h 20m
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Lufthansa1h 20m012:00Frankfurt am Main AirportFrankfurt am Main Airport13:20Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 10/05/2026 12:00:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 10/05/2026 13:20:00. 50 Economy ticket for £191 per person are available. Travel duration is 1h 20m
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Air Dolomiti1h 20m008:20Frankfurt am Main AirportFrankfurt am Main Airport09:40Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Air Dolomiti goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 10/05/2026 08:20:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 10/05/2026 09:40:00. 50 Economy ticket for £200 per person are available. Travel duration is 1h 20m
Cheapest Buses Sunday
Cheapest Flights Sunday
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FlixBus12h 35m008:15Frankfurt am MainCentral Station20:50LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 11/05/2026 08:15:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 11/05/2026 20:50:00. 50 Economy ticket for £37 per person are available. Travel duration is 12h 35m
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BlaBlaCar Bus16h 5m012:00Frankfurt am MainCentral Coach Station04:05LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Central Coach Station, Frankfurt am Main (Germany) at 11/05/2026 12:00:00 to Perrache Train Station, Lyon (France) arriving at 12/05/2026 04:05:00. 50 Economy ticket for £37 per person are available. Travel duration is 16h 5m
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FlixBus9h 40m019:05Frankfurt am MainCentral Station04:45LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 11/05/2026 19:05:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 12/05/2026 04:45:00. 50 Economy ticket for £40 per person are available. Travel duration is 9h 40m
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FlixBus11h 55m011:20Frankfurt am MainCentral Station23:15LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 11/05/2026 11:20:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 11/05/2026 23:15:00. 50 Economy ticket for £41 per person are available. Travel duration is 11h 55m
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Lufthansa1h 20m021:40Frankfurt am Main AirportFrankfurt am Main Airport23:00Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 11/05/2026 21:40:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 11/05/2026 23:00:00. 50 Economy ticket for £163 per person are available. Travel duration is 1h 20m
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Lufthansa1h 20m012:00Frankfurt am Main AirportFrankfurt am Main Airport13:20Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 11/05/2026 12:00:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 11/05/2026 13:20:00. 50 Economy ticket for £165 per person are available. Travel duration is 1h 20m
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Air Dolomiti1h 20m008:40Frankfurt am Main AirportFrankfurt am Main Airport10:00Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Air Dolomiti goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 11/05/2026 08:40:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 11/05/2026 10:00:00. 50 Economy ticket for £190 per person are available. Travel duration is 1h 20m
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Air Dolomiti1h 20m008:40Frankfurt am Main AirportFrankfurt am Main Airport10:00Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Air Dolomiti goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 11/05/2026 08:40:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 11/05/2026 10:00:00. 50 Economy ticket for £225 per person are available. Travel duration is 1h 20m
Cheapest Buses Monday
Cheapest Flights Monday
What are the fastest trips from Frankfurt am Main to Lyon?
You can get to Lyon from Frankfurt am Main in just 1h 20m with a Flight from Air Dolomiti. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
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FlixBus9h 40m019:05Frankfurt am MainCentral Station04:45LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 05/05/2026 19:05:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 06/05/2026 04:45:00. 50 Economy ticket for £40 per person are available. Travel duration is 9h 40m
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FlixBus11h 55m011:20Frankfurt am MainCentral Station23:15LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 05/05/2026 11:20:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 05/05/2026 23:15:00. 50 Economy ticket for £38 per person are available. Travel duration is 11h 55m
Fastest Buses Tuesday
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FlixBus9h 40m019:05Frankfurt am MainCentral Station04:45LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 06/05/2026 19:05:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 07/05/2026 04:45:00. 50 Economy ticket for £40 per person are available. Travel duration is 9h 40m
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BlaBlaCar Bus11h 50m008:55Frankfurt am MainCentral Coach Station20:45LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Central Coach Station, Frankfurt am Main (Germany) at 06/05/2026 08:55:00 to Perrache Train Station, Lyon (France) arriving at 06/05/2026 20:45:00. 50 Economy ticket for £35 per person are available. Travel duration is 11h 50m
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FlixBus11h 55m011:20Frankfurt am MainCentral Station23:15LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 06/05/2026 11:20:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 06/05/2026 23:15:00. 50 Economy ticket for £50 per person are available. Travel duration is 11h 55m
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FlixBus12h 35m008:15Frankfurt am MainCentral Station20:50LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 06/05/2026 08:15:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 06/05/2026 20:50:00. 50 Economy ticket for £39 per person are available. Travel duration is 12h 35m
Fastest Buses Wednesday
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FlixBus9h 40m019:05Frankfurt am MainCentral Station04:45LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 07/05/2026 19:05:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 08/05/2026 04:45:00. 50 Economy ticket for £59 per person are available. Travel duration is 9h 40m
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FlixBus11h 45m022:45Frankfurt am MainCentral Station10:30LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 07/05/2026 22:45:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 08/05/2026 10:30:00. 50 Economy ticket for £47 per person are available. Travel duration is 11h 45m
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FlixBus11h 55m011:20Frankfurt am MainCentral Station23:15LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 07/05/2026 11:20:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 07/05/2026 23:15:00. 50 Economy ticket for £46 per person are available. Travel duration is 11h 55m
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FlixBus12h 35m008:15Frankfurt am MainCentral Station20:50LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 07/05/2026 08:15:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 07/05/2026 20:50:00. 50 Economy ticket for £40 per person are available. Travel duration is 12h 35m
Fastest Buses Thursday
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Air Dolomiti1h 20m008:40Frankfurt am Main AirportFrankfurt am Main Airport10:00Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Air Dolomiti goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 08/05/2026 08:40:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 08/05/2026 10:00:00. 50 Economy ticket for £166 per person are available. Travel duration is 1h 20m
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Lufthansa1h 20m016:50Frankfurt am Main AirportFrankfurt am Main Airport18:10Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 08/05/2026 16:50:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 08/05/2026 18:10:00. 50 Economy ticket for £166 per person are available. Travel duration is 1h 20m
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Lufthansa1h 20m008:40Frankfurt am Main AirportFrankfurt am Main Airport10:00Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 08/05/2026 08:40:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 08/05/2026 10:00:00. 50 Economy ticket for £166 per person are available. Travel duration is 1h 20m
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Lufthansa1h 20m012:35Frankfurt am Main AirportFrankfurt am Main Airport13:55Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 08/05/2026 12:35:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 08/05/2026 13:55:00. 50 Economy ticket for £166 per person are available. Travel duration is 1h 20m
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TGV Lyria5h 56m014:02Frankfurt am MainCentral Station19:58LyonPart-Dieu Train Station0EconomyA Train from TGV Lyria goes from Central Station, Frankfurt am Main (Germany) at 08/05/2026 14:02:00 to Part-Dieu Train Station, Lyon (France) arriving at 08/05/2026 19:58:00. 50 Economy ticket for £78 per person are available. Travel duration is 5h 56m
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TGV Lyria7h 1m012:53Frankfurt am MainCentral Station19:54LyonPart-Dieu Train Station0EconomyA Train from TGV Lyria goes from Central Station, Frankfurt am Main (Germany) at 08/05/2026 12:53:00 to Part-Dieu Train Station, Lyon (France) arriving at 08/05/2026 19:54:00. 50 Economy ticket for £150 per person are available. Travel duration is 7h 1m
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FlixBus9h 40m019:05Frankfurt am MainCentral Station04:45LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 08/05/2026 19:05:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 09/05/2026 04:45:00. 50 Economy ticket for £40 per person are available. Travel duration is 9h 40m
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BlaBlaCar Bus10h 40m018:30Frankfurt am MainCentral Coach Station05:10LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Central Coach Station, Frankfurt am Main (Germany) at 08/05/2026 18:30:00 to Perrache Train Station, Lyon (France) arriving at 09/05/2026 05:10:00. 50 Economy ticket for £30 per person are available. Travel duration is 10h 40m
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BlaBlaCar Bus11h 50m008:55Frankfurt am MainCentral Coach Station20:45LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Central Coach Station, Frankfurt am Main (Germany) at 08/05/2026 08:55:00 to Perrache Train Station, Lyon (France) arriving at 08/05/2026 20:45:00. 50 Economy ticket for £35 per person are available. Travel duration is 11h 50m
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FlixBus11h 55m011:20Frankfurt am MainCentral Station23:15LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 08/05/2026 11:20:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 08/05/2026 23:15:00. 50 Economy ticket for £47 per person are available. Travel duration is 11h 55m
Fastest Flights Friday
Fastest Trains Friday
Fastest Buses Friday
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Lufthansa1h 20m012:00Frankfurt am Main AirportFrankfurt am Main Airport13:20Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 09/05/2026 12:00:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 09/05/2026 13:20:00. 50 Economy ticket for £150 per person are available. Travel duration is 1h 20m
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Air Dolomiti1h 20m008:30Frankfurt am Main AirportFrankfurt am Main Airport09:50Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Air Dolomiti goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 09/05/2026 08:30:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 09/05/2026 09:50:00. 50 Economy ticket for £163 per person are available. Travel duration is 1h 20m
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Lufthansa1h 20m008:30Frankfurt am Main AirportFrankfurt am Main Airport09:50Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 09/05/2026 08:30:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 09/05/2026 09:50:00. 50 Economy ticket for £166 per person are available. Travel duration is 1h 20m
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Lufthansa1h 20m016:50Frankfurt am Main AirportFrankfurt am Main Airport18:10Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 09/05/2026 16:50:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 09/05/2026 18:10:00. 50 Economy ticket for £188 per person are available. Travel duration is 1h 20m
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FlixBus9h 35m019:30Frankfurt am Main AirportFrankfurt am Main Airport05:05LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 09/05/2026 19:30:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 10/05/2026 05:05:00. 50 Economy ticket for £39 per person are available. Travel duration is 9h 35m
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BlaBlaCar Bus10h 40m018:30Frankfurt am MainCentral Coach Station05:10LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Central Coach Station, Frankfurt am Main (Germany) at 09/05/2026 18:30:00 to Perrache Train Station, Lyon (France) arriving at 10/05/2026 05:10:00. 50 Economy ticket for £27 per person are available. Travel duration is 10h 40m
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FlixBus11h 25m023:05Frankfurt am Main AirportFrankfurt am Main Airport10:30LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 09/05/2026 23:05:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 10/05/2026 10:30:00. 50 Economy ticket for £40 per person are available. Travel duration is 11h 25m
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FlixBus11h 45m022:45Frankfurt am MainCentral Station10:30LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 09/05/2026 22:45:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 10/05/2026 10:30:00. 50 Economy ticket for £40 per person are available. Travel duration is 11h 45m
Fastest Flights Saturday
Fastest Buses Saturday
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Lufthansa1h 20m008:20Frankfurt am Main AirportFrankfurt am Main Airport09:40Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 10/05/2026 08:20:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 10/05/2026 09:40:00. 50 Economy ticket for £163 per person are available. Travel duration is 1h 20m
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Air Dolomiti1h 20m008:20Frankfurt am Main AirportFrankfurt am Main Airport09:40Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Air Dolomiti goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 10/05/2026 08:20:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 10/05/2026 09:40:00. 50 Economy ticket for £164 per person are available. Travel duration is 1h 20m
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Lufthansa1h 20m012:00Frankfurt am Main AirportFrankfurt am Main Airport13:20Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 10/05/2026 12:00:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 10/05/2026 13:20:00. 50 Economy ticket for £191 per person are available. Travel duration is 1h 20m
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Air Dolomiti1h 20m008:20Frankfurt am Main AirportFrankfurt am Main Airport09:40Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Air Dolomiti goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 10/05/2026 08:20:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 10/05/2026 09:40:00. 50 Economy ticket for £200 per person are available. Travel duration is 1h 20m
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FlixBus9h 35m019:30Frankfurt am Main AirportFrankfurt am Main Airport05:05LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 10/05/2026 19:30:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 11/05/2026 05:05:00. 50 Economy ticket for £41 per person are available. Travel duration is 9h 35m
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BlaBlaCar Bus10h 40m018:30Frankfurt am MainCentral Coach Station05:10LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Central Coach Station, Frankfurt am Main (Germany) at 10/05/2026 18:30:00 to Perrache Train Station, Lyon (France) arriving at 11/05/2026 05:10:00. 50 Economy ticket for £30 per person are available. Travel duration is 10h 40m
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FlixBus11h 25m023:05Frankfurt am Main AirportFrankfurt am Main Airport10:30LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 10/05/2026 23:05:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 11/05/2026 10:30:00. 50 Economy ticket for £43 per person are available. Travel duration is 11h 25m
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FlixBus11h 45m022:45Frankfurt am MainCentral Station10:30LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 10/05/2026 22:45:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 11/05/2026 10:30:00. 50 Economy ticket for £43 per person are available. Travel duration is 11h 45m
Fastest Flights Sunday
Fastest Buses Sunday
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Lufthansa1h 20m021:40Frankfurt am Main AirportFrankfurt am Main Airport23:00Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 11/05/2026 21:40:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 11/05/2026 23:00:00. 50 Economy ticket for £163 per person are available. Travel duration is 1h 20m
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Lufthansa1h 20m012:00Frankfurt am Main AirportFrankfurt am Main Airport13:20Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 11/05/2026 12:00:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 11/05/2026 13:20:00. 50 Economy ticket for £165 per person are available. Travel duration is 1h 20m
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Air Dolomiti1h 20m008:40Frankfurt am Main AirportFrankfurt am Main Airport10:00Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Air Dolomiti goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 11/05/2026 08:40:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 11/05/2026 10:00:00. 50 Economy ticket for £190 per person are available. Travel duration is 1h 20m
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Air Dolomiti1h 20m008:40Frankfurt am Main AirportFrankfurt am Main Airport10:00Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Air Dolomiti goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 11/05/2026 08:40:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 11/05/2026 10:00:00. 50 Economy ticket for £225 per person are available. Travel duration is 1h 20m
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FlixBus9h 40m019:05Frankfurt am MainCentral Station04:45LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 11/05/2026 19:05:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 12/05/2026 04:45:00. 50 Economy ticket for £40 per person are available. Travel duration is 9h 40m
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FlixBus11h 55m011:20Frankfurt am MainCentral Station23:15LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 11/05/2026 11:20:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 11/05/2026 23:15:00. 50 Economy ticket for £41 per person are available. Travel duration is 11h 55m
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FlixBus12h 35m008:15Frankfurt am MainCentral Station20:50LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 11/05/2026 08:15:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 11/05/2026 20:50:00. 50 Economy ticket for £37 per person are available. Travel duration is 12h 35m
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BlaBlaCar Bus16h 5m012:00Frankfurt am MainCentral Coach Station04:05LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Central Coach Station, Frankfurt am Main (Germany) at 11/05/2026 12:00:00 to Perrache Train Station, Lyon (France) arriving at 12/05/2026 04:05:00. 50 Economy ticket for £37 per person are available. Travel duration is 16h 5m
Fastest Flights Monday
Fastest Buses Monday
Here you will find all operators and timetables for a
Bus from Frankfurt am Main to Lyon
What are the most popular stations in Frankfurt am Main and Lyon?
In Frankfurt am Main, you will usually depart from Central Station, Central Coach Station or West Train Station, while in Lyon you will be arriving at Part-Dieu Train Station, Perrache Train Station or Perrache Bus Stop, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Lyon from Frankfurt am Main? With 7 connections between 4 Train, Flight and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Frankfurt am Main and Lyon, you can pay as low as £27 with a Bus from BlaBlaCar Bus.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Air Dolomiti: you will get to Lyon in just 1h 20m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Frankfurt am Main and Lyon are FlixBus, Lufthansa and BlaBlaCar Bus, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Frankfurt am Main and Lyon is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Neu-Isenburg or to Caluire-et-Cuire, and look at flights from Frankfurt am Main Airport, and landing at Lyons St. Exupery Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Frankfurt am Main to Lyon?
The most popular companies between Frankfurt am Main and Lyon, are FlixBus, Lufthansa and BlaBlaCar Bus. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: FlixBus and BlaBlaCar Bus
Train companies: TGV Lyria
Airlines: Lufthansa and Air Dolomiti
All you need to know when you travel from Frankfurt am Main to Lyon
Check all information on comfort and services on all modes of transports from Frankfurt am Main to Lyon. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Frankfurt am Main to Lyon
How can I reach Lyon from Frankfurt am Main?
Every day, there are on average 7 connections between Train, Flight and Bus, with which you can get to Lyon from Frankfurt am Main.
How far is Lyon from Frankfurt am Main?
The distance between Frankfurt am Main and Lyon is 562.3 km.
What is the most ecofriendly mode of transport between Frankfurt am Main and Lyon?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 15 kgs of CO2, a train 20 kgs, a car 96 kgs, and a flight 138 kgs.
What is the cheapest mode of transport from Frankfurt am Main to Lyon?
You can get to Lyon with just £27 by taking a Bus from BlaBlaCar Bus.
What is the fastest way to get from Frankfurt am Main to Lyon?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Lyon in just 1h 20m with a Flight from Air Dolomiti.
More routes to Frankfurt am Main and to Lyon
Looking for more options? Here you can see the most popular routes to Frankfurt am Main and to Lyon. Simply click on a connection, and you’ll find all the details about the route!
