Which bus from Chicago to San Antonio, TX is the best?
Check the bus schedule for Chicago to San Antonio, TX. Here is a selection of the cheapest coach trips for the next days from bus operators like Greyhound US or FlixBus. To see the full timetable for all coaches just use or search and compare.
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 46h 40m | 22:30 | Chicago | Downtown Coach Station | 21:10 | San Antonio, TX | Pearl District | Economy | £139 |
A Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 15/12/2025 22:30:00 to Pearl District, San Antonio, TX (USA) arriving at 17/12/2025 21:10:00. 50 Economy ticket for £139 per person are available. Travel duration is 46h 40m
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| Greyhound US | 30h 45m | 06:10 | Chicago | Downtown Coach Station | 12:55 | San Antonio, TX | Coach Station | Economy | £141 |
A Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 15/12/2025 06:10:00 to Coach Station, San Antonio, TX (USA) arriving at 16/12/2025 12:55:00. 50 Economy ticket for £141 per person are available. Travel duration is 30h 45m
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| Greyhound US | 31h 55m | 09:40 | Chicago | Downtown Coach Station | 17:35 | San Antonio, TX | Coach Station | Economy | £141 |
A Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 15/12/2025 09:40:00 to Coach Station, San Antonio, TX (USA) arriving at 16/12/2025 17:35:00. 50 Economy ticket for £141 per person are available. Travel duration is 31h 55m
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| Greyhound US | 31h 35m | 10:00 | Chicago | Union Station | 17:35 | San Antonio, TX | Coach Station | Economy | £141 |
A Bus from Greyhound US goes from Union Station, Chicago (USA) at 15/12/2025 10:00:00 to Coach Station, San Antonio, TX (USA) arriving at 16/12/2025 17:35:00. 50 Economy ticket for £141 per person are available. Travel duration is 31h 35m
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| Greyhound US | 40h 10m | 23:10 | Chicago | Union Station | 15:20 | San Antonio, TX | Coach Station | Economy | £141 |
A Bus from Greyhound US goes from Union Station, Chicago (USA) at 15/12/2025 23:10:00 to Coach Station, San Antonio, TX (USA) arriving at 17/12/2025 15:20:00. 50 Economy ticket for £141 per person are available. Travel duration is 40h 10m
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Busbud28h 25m019:25Chicago95th Red Line Station18:00DallasCoach Station0EconomyA Bus from Busbud goes from 95th Red Line Station, Chicago (USA) at 16/12/2025 19:25:00 to Coach Station, Dallas (USA) arriving at 17/12/2025 18:00:00. 50 Economy ticket for £83 per person are available. Travel duration is 22h 35m
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Busbud5h 20m018:30DallasCoach Station23:50San Antonio, TXCoach Station0EconomyA Bus from Busbud goes from Coach Station, Dallas (USA) at 17/12/2025 18:30:00 to Coach Station, San Antonio, TX (USA) arriving at 17/12/2025 23:50:00. 50 Economy ticket for £28 per person are available. Travel duration is 5h 20m
Waiting Time 0h 30m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 25h 25m | 22:30 | Chicago | Downtown Coach Station | 23:55 | San Antonio, TX | Coach Station | Economy | £140 |
A Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 16/12/2025 22:30:00 to Coach Station, San Antonio, TX (USA) arriving at 17/12/2025 23:55:00. 50 Economy ticket for £140 per person are available. Travel duration is 25h 25m
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| Greyhound US | 40h 10m | 23:10 | Chicago | Union Station | 15:20 | San Antonio, TX | Coach Station | Economy | £141 |
A Bus from Greyhound US goes from Union Station, Chicago (USA) at 16/12/2025 23:10:00 to Coach Station, San Antonio, TX (USA) arriving at 18/12/2025 15:20:00. 50 Economy ticket for £141 per person are available. Travel duration is 40h 10m
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| Greyhound US | 31h 55m | 09:40 | Chicago | Downtown Coach Station | 17:35 | San Antonio, TX | Coach Station | Economy | £153 |
A Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 16/12/2025 09:40:00 to Coach Station, San Antonio, TX (USA) arriving at 17/12/2025 17:35:00. 50 Economy ticket for £153 per person are available. Travel duration is 31h 55m
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| Greyhound US | 31h 35m | 10:00 | Chicago | Union Station | 17:35 | San Antonio, TX | Coach Station | Economy | £153 |
A Bus from Greyhound US goes from Union Station, Chicago (USA) at 16/12/2025 10:00:00 to Coach Station, San Antonio, TX (USA) arriving at 17/12/2025 17:35:00. 50 Economy ticket for £153 per person are available. Travel duration is 31h 35m
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| Greyhound US | 30h 45m | 06:10 | Chicago | Downtown Coach Station | 12:55 | San Antonio, TX | Coach Station | Economy | £159 |
A Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 16/12/2025 06:10:00 to Coach Station, San Antonio, TX (USA) arriving at 17/12/2025 12:55:00. 50 Economy ticket for £159 per person are available. Travel duration is 30h 45m
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Busbud28h 25m019:25Chicago95th Red Line Station18:00DallasCoach Station0EconomyA Bus from Busbud goes from 95th Red Line Station, Chicago (USA) at 16/12/2025 19:25:00 to Coach Station, Dallas (USA) arriving at 17/12/2025 18:00:00. 50 Economy ticket for £83 per person are available. Travel duration is 22h 35m
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Busbud5h 20m018:30DallasCoach Station23:50San Antonio, TXCoach Station0EconomyA Bus from Busbud goes from Coach Station, Dallas (USA) at 17/12/2025 18:30:00 to Coach Station, San Antonio, TX (USA) arriving at 17/12/2025 23:50:00. 50 Economy ticket for £28 per person are available. Travel duration is 5h 20m
Waiting Time 0h 30m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 48h 35m | 22:50 | Chicago | Downtown Coach Station | 23:25 | San Antonio, TX | Pearl District | Economy | £163 |
A Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 18/12/2025 22:50:00 to Pearl District, San Antonio, TX (USA) arriving at 20/12/2025 23:25:00. 50 Economy ticket for £163 per person are available. Travel duration is 48h 35m
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| Greyhound US | 48h 15m | 23:10 | Chicago | Union Station | 23:25 | San Antonio, TX | Pearl District | Economy | £163 |
A Bus from Greyhound US goes from Union Station, Chicago (USA) at 18/12/2025 23:10:00 to Pearl District, San Antonio, TX (USA) arriving at 20/12/2025 23:25:00. 50 Economy ticket for £163 per person are available. Travel duration is 48h 15m
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| FlixBus | 37h 40m | 09:45 | Chicago | Downtown Coach Station | 23:25 | San Antonio, TX | Pearl District | Economy | £165 |
A Bus from FlixBus goes from Downtown Coach Station, Chicago (USA) at 18/12/2025 09:45:00 to Pearl District, San Antonio, TX (USA) arriving at 19/12/2025 23:25:00. 50 Economy ticket for £165 per person are available. Travel duration is 37h 40m
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| FlixBus | 27h 10m | 09:45 | Chicago | Downtown Coach Station | 12:55 | San Antonio, TX | Coach Station | Economy | £176 |
A Bus from FlixBus goes from Downtown Coach Station, Chicago (USA) at 18/12/2025 09:45:00 to Coach Station, San Antonio, TX (USA) arriving at 19/12/2025 12:55:00. 50 Economy ticket for £176 per person are available. Travel duration is 27h 10m
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| Greyhound US | 31h 35m | 10:00 | Chicago | Union Station | 17:35 | San Antonio, TX | Coach Station | Economy | £177 |
A Bus from Greyhound US goes from Union Station, Chicago (USA) at 18/12/2025 10:00:00 to Coach Station, San Antonio, TX (USA) arriving at 19/12/2025 17:35:00. 50 Economy ticket for £177 per person are available. Travel duration is 31h 35m
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Busbud28h 25m019:25Chicago95th Red Line Station18:00DallasCoach Station0EconomyA Bus from Busbud goes from 95th Red Line Station, Chicago (USA) at 16/12/2025 19:25:00 to Coach Station, Dallas (USA) arriving at 17/12/2025 18:00:00. 50 Economy ticket for £83 per person are available. Travel duration is 22h 35m
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Busbud5h 20m018:30DallasCoach Station23:50San Antonio, TXCoach Station0EconomyA Bus from Busbud goes from Coach Station, Dallas (USA) at 17/12/2025 18:30:00 to Coach Station, San Antonio, TX (USA) arriving at 17/12/2025 23:50:00. 50 Economy ticket for £28 per person are available. Travel duration is 5h 20m
Waiting Time 0h 30m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 48h 35m | 22:50 | Chicago | Downtown Coach Station | 23:25 | San Antonio, TX | Pearl District | Economy | £186 |
A Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 21/12/2025 22:50:00 to Pearl District, San Antonio, TX (USA) arriving at 23/12/2025 23:25:00. 50 Economy ticket for £186 per person are available. Travel duration is 48h 35m
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| Greyhound US | 48h 15m | 23:10 | Chicago | Union Station | 23:25 | San Antonio, TX | Pearl District | Economy | £186 |
A Bus from Greyhound US goes from Union Station, Chicago (USA) at 21/12/2025 23:10:00 to Pearl District, San Antonio, TX (USA) arriving at 23/12/2025 23:25:00. 50 Economy ticket for £186 per person are available. Travel duration is 48h 15m
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| FlixBus | 37h 40m | 09:45 | Chicago | Downtown Coach Station | 23:25 | San Antonio, TX | Pearl District | Economy | £190 |
A Bus from FlixBus goes from Downtown Coach Station, Chicago (USA) at 21/12/2025 09:45:00 to Pearl District, San Antonio, TX (USA) arriving at 22/12/2025 23:25:00. 50 Economy ticket for £190 per person are available. Travel duration is 37h 40m
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| Greyhound US | 40h 10m | 23:10 | Chicago | Union Station | 15:20 | San Antonio, TX | Coach Station | Economy | £199 |
A Bus from Greyhound US goes from Union Station, Chicago (USA) at 21/12/2025 23:10:00 to Coach Station, San Antonio, TX (USA) arriving at 23/12/2025 15:20:00. 50 Economy ticket for £199 per person are available. Travel duration is 40h 10m
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| FlixBus | 27h 10m | 09:45 | Chicago | Downtown Coach Station | 12:55 | San Antonio, TX | Coach Station | Economy | £244 |
A Bus from FlixBus goes from Downtown Coach Station, Chicago (USA) at 21/12/2025 09:45:00 to Coach Station, San Antonio, TX (USA) arriving at 22/12/2025 12:55:00. 50 Economy ticket for £244 per person are available. Travel duration is 27h 10m
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Busbud28h 25m019:25Chicago95th Red Line Station18:00DallasCoach Station0EconomyA Bus from Busbud goes from 95th Red Line Station, Chicago (USA) at 16/12/2025 19:25:00 to Coach Station, Dallas (USA) arriving at 17/12/2025 18:00:00. 50 Economy ticket for £83 per person are available. Travel duration is 22h 35m
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Busbud5h 20m018:30DallasCoach Station23:50San Antonio, TXCoach Station0EconomyA Bus from Busbud goes from Coach Station, Dallas (USA) at 17/12/2025 18:30:00 to Coach Station, San Antonio, TX (USA) arriving at 17/12/2025 23:50:00. 50 Economy ticket for £28 per person are available. Travel duration is 5h 20m
Waiting Time 0h 30m -
Best Price Offer: The price for the cheapest coach from Chicago to San Antonio, TX is £89 on 25/12/2025. Flexible travellers save on ticket prices.
What is the best day and time to travel by bus between Chicago and San Antonio, TX?
All facts for Chicago to San Antonio, TX bus at a glance
Compare all coach operators like Greyhound US and FlixBus that travel daily 6 times by bus from Chicago to San Antonio, TX in one click. Book your Chicago to San Antonio, TX bus ticket starting from £89!
| Cheapest Bus | £89 |
| Fastest Bus | 25h 25m |
| Earliest Coach | 06:10 |
| Latest Coach | 23:10 |
| Daily Bus Connections | 6 Ø |
| Distance | 1,692.8 km |
| Coach Companies | Greyhound US and FlixBus |
What are the cheapest coach tickets from Chicago to San Antonio, TX?
Every day, 6 buses from 2 coach companies leave Chicago for San Antonio, TX. Check the table below to find the cheapest prices for coach tickets for this route, starting from 15/12/2025 and for the following days. Make sure get the cheapest bus ticket!
The cheapest time to travel from Chicago to San Antonio, TX
How to save money travelling from Chicago to San Antonio, TX
Book the ticket from Chicago to San Antonio, TX in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the coach from Chicago to San Antonio, TX, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Chicago to San Antonio, TX are also emptier.Check for bus deals and promotions for all bus companies in this route. On CheckMyBus we show special offers directly in the coach trip on our search. Sign-up and check or deals sections and get notifications on our latest travel hacks.
All bus stations and stops in Chicago and San Antonio, TX
Here is a map with all coach stations in Chicago and San Antonio, TX. Compare which stop is closest to your destination to save time to find the fastest buses and connections.
Compare the bus with other modes of transport
All you need to know when you travel by bus from Chicago to San Antonio, TX
FAQs for Chicago to San Antonio, TX bus
How much does a Chicago San Antonio, TX coach trip cost?
How much could I save by comparing buses from Chicago to San Antonio, TX?
How many connections are available for the Chicago San Antonio, TX route on average every day?
How long does a bus to San Antonio, TX from Chicago take?
What time is the first bus from Chicago to San Antonio, TX?
What time is the last coach from Chicago to San Antonio, TX?
Which bus companies serve the Chicago San Antonio, TX route?
Is there a direct bus between Chicago and San Antonio, TX?
What can I take with me on the bus to San Antonio, TX from Chicago?
What equipment is available for the Chicago San Antonio, TX bus route?
How does CheckMyBus find the best coach deals from Chicago to San Antonio, TX?
How does CheckMyBus technology work for trips from Chicago to San Antonio, TX?
Available seat classes which are offered on the bus route Chicago to San Antonio, TX
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
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