What is the best way to travel from Madrid to Lyon?
Looking for a trip? Check and compare all the available Buses and Flights to Lyon from Madrid. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 4 available companies to find your perfect trip!
What is the cheapest way to reach Lyon from Madrid?
You can reach Lyon with just £40 by taking a Bus from ALSA, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
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ALSA17h 0m011:55Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T404:55LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 04/12/2025 11:55:00 to Perrache Bus Stop, Lyon (France) arriving at 05/12/2025 04:55:00. 50 Economy ticket for £49 per person are available. Travel duration is 17h 0m
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BlaBlaCar Bus24h 10m018:35MadridSur Bus Station18:45LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 04/12/2025 18:35:00 to Perrache Train Station, Lyon (France) arriving at 05/12/2025 18:45:00. 50 Economy ticket for £70 per person are available. Travel duration is 24h 10m
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BlaBlaCar Bus19h 40m022:30MadridSur Bus Station18:10LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 04/12/2025 22:30:00 to Perrache Train Station, Lyon (France) arriving at 05/12/2025 18:10:00. 50 Economy ticket for £84 per person are available. Travel duration is 19h 40m
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FlixBus20h 20m015:45MadridSur Bus Station12:05LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 04/12/2025 15:45:00 to Perrache Bus Stop, Lyon (France) arriving at 05/12/2025 12:05:00. 50 Economy ticket for £94 per person are available. Travel duration is 20h 20m
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FlixBus20h 0m014:50MadridSur Bus Station10:50LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 04/12/2025 14:50:00 to Perrache Bus Stop, Lyon (France) arriving at 05/12/2025 10:50:00. 50 Economy ticket for £95 per person are available. Travel duration is 20h 0m
Cheapest Buses Thursday
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BlaBlaCar Bus17h 25m008:35MadridSur Bus Station02:00LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 05/12/2025 08:35:00 to Perrache Train Station, Lyon (France) arriving at 06/12/2025 02:00:00. 50 Economy ticket for £47 per person are available. Travel duration is 17h 25m
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BlaBlaCar Bus19h 40m022:30MadridSur Bus Station18:10LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 05/12/2025 22:30:00 to Perrache Train Station, Lyon (France) arriving at 06/12/2025 18:10:00. 50 Economy ticket for £51 per person are available. Travel duration is 19h 40m
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Union Ivkoni23h 0m010:00MadridMendez Alvaro Train Station09:00LyonPerrache Bus Stop0BasicA Bus from Union Ivkoni goes from Mendez Alvaro Train Station, Madrid (Spain) at 05/12/2025 10:00:00 to Perrache Bus Stop, Lyon (France) arriving at 06/12/2025 09:00:00. 50 Basic ticket for £51 per person are available. Travel duration is 23h 0m
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ALSA18h 30m010:45Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T405:15LyonPerrache Bus Stop0BasicA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 05/12/2025 10:45:00 to Perrache Bus Stop, Lyon (France) arriving at 06/12/2025 05:15:00. 50 Basic ticket for £57 per person are available. Travel duration is 18h 30m
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ALSA18h 10m010:45Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T404:55LyonPerrache Bus Stop0BasicA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 05/12/2025 10:45:00 to Perrache Bus Stop, Lyon (France) arriving at 06/12/2025 04:55:00. 50 Basic ticket for £57 per person are available. Travel duration is 18h 10m
Cheapest Buses Friday
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ALSA18h 10m010:45Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T404:55LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 06/12/2025 10:45:00 to Perrache Bus Stop, Lyon (France) arriving at 07/12/2025 04:55:00. 50 Economy ticket for £40 per person are available. Travel duration is 18h 10m
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ALSA17h 0m011:55Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T404:55LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 06/12/2025 11:55:00 to Perrache Bus Stop, Lyon (France) arriving at 07/12/2025 04:55:00. 50 Economy ticket for £40 per person are available. Travel duration is 17h 0m
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BlaBlaCar Bus19h 40m022:30MadridSur Bus Station18:10LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 06/12/2025 22:30:00 to Perrache Train Station, Lyon (France) arriving at 07/12/2025 18:10:00. 50 Economy ticket for £56 per person are available. Travel duration is 19h 40m
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FlixBus16h 40m020:50MadridSur Bus Station13:30LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 06/12/2025 20:50:00 to Perrache Bus Stop, Lyon (France) arriving at 07/12/2025 13:30:00. 50 Economy ticket for £58 per person are available. Travel duration is 16h 40m
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BlaBlaCar Bus24h 10m018:35MadridSur Bus Station18:45LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 06/12/2025 18:35:00 to Perrache Train Station, Lyon (France) arriving at 07/12/2025 18:45:00. 50 Economy ticket for £66 per person are available. Travel duration is 24h 10m
Cheapest Buses Saturday
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ALSA17h 0m011:55Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T404:55LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 07/12/2025 11:55:00 to Perrache Bus Stop, Lyon (France) arriving at 08/12/2025 04:55:00. 50 Economy ticket for £45 per person are available. Travel duration is 17h 0m
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Union Ivkoni22h 30m010:00MadridMendez Alvaro Train Station08:30LyonPerrache Bus Stop0BasicA Bus from Union Ivkoni goes from Mendez Alvaro Train Station, Madrid (Spain) at 07/12/2025 10:00:00 to Perrache Bus Stop, Lyon (France) arriving at 08/12/2025 08:30:00. 50 Basic ticket for £51 per person are available. Travel duration is 22h 30m
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ALSA19h 30m022:45Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T418:15LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 07/12/2025 22:45:00 to Perrache Bus Stop, Lyon (France) arriving at 08/12/2025 18:15:00. 50 Economy ticket for £54 per person are available. Travel duration is 19h 30m
Cheapest Buses Sunday
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ALSA18h 1m000:14Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T418:15LyonPerrache Bus Stop0BasicA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 08/12/2025 00:14:00 to Perrache Bus Stop, Lyon (France) arriving at 08/12/2025 18:15:00. 50 Basic ticket for £52 per person are available. Travel duration is 18h 1m
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ALSA18h 40m010:15Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T404:55LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 08/12/2025 10:15:00 to Perrache Bus Stop, Lyon (France) arriving at 09/12/2025 04:55:00. 50 Economy ticket for £54 per person are available. Travel duration is 18h 40m
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FlixBus16h 40m020:50MadridSur Bus Station13:30LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 08/12/2025 20:50:00 to Perrache Bus Stop, Lyon (France) arriving at 09/12/2025 13:30:00. 50 Economy ticket for £56 per person are available. Travel duration is 16h 40m
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FlixBus20h 20m020:50Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T417:10LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 08/12/2025 20:50:00 to Perrache Bus Stop, Lyon (France) arriving at 09/12/2025 17:10:00. 50 Economy ticket for £72 per person are available. Travel duration is 20h 20m
Cheapest Buses Monday
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ALSA19h 30m022:45Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T418:15LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 09/12/2025 22:45:00 to Perrache Bus Stop, Lyon (France) arriving at 10/12/2025 18:15:00. 50 Economy ticket for £45 per person are available. Travel duration is 19h 30m
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ALSA18h 30m023:45Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T418:15LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 09/12/2025 23:45:00 to Perrache Bus Stop, Lyon (France) arriving at 10/12/2025 18:15:00. 50 Economy ticket for £45 per person are available. Travel duration is 18h 30m
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Union Ivkoni22h 0m010:00MadridMendez Alvaro Train Station08:00LyonPerrache Bus Stop0BasicA Bus from Union Ivkoni goes from Mendez Alvaro Train Station, Madrid (Spain) at 09/12/2025 10:00:00 to Perrache Bus Stop, Lyon (France) arriving at 10/12/2025 08:00:00. 50 Basic ticket for £51 per person are available. Travel duration is 22h 0m
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FlixBus16h 40m020:50MadridSur Bus Station13:30LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 09/12/2025 20:50:00 to Perrache Bus Stop, Lyon (France) arriving at 10/12/2025 13:30:00. 50 Economy ticket for £53 per person are available. Travel duration is 16h 40m
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FlixBus20h 0m014:50MadridSur Bus Station10:50LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 09/12/2025 14:50:00 to Perrache Bus Stop, Lyon (France) arriving at 10/12/2025 10:50:00. 50 Economy ticket for £62 per person are available. Travel duration is 20h 0m
Cheapest Buses Tuesday
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ALSA18h 1m000:14Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T418:15LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 10/12/2025 00:14:00 to Perrache Bus Stop, Lyon (France) arriving at 10/12/2025 18:15:00. 50 Economy ticket for £45 per person are available. Travel duration is 18h 1m
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ALSA17h 0m011:55Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T404:55LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 10/12/2025 11:55:00 to Perrache Bus Stop, Lyon (France) arriving at 11/12/2025 04:55:00. 50 Economy ticket for £45 per person are available. Travel duration is 17h 0m
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BlaBlaCar Bus17h 25m008:35MadridSur Bus Station02:00LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 10/12/2025 08:35:00 to Perrache Train Station, Lyon (France) arriving at 11/12/2025 02:00:00. 50 Economy ticket for £50 per person are available. Travel duration is 17h 25m
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FlixBus16h 40m020:50MadridSur Bus Station13:30LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 10/12/2025 20:50:00 to Perrache Bus Stop, Lyon (France) arriving at 11/12/2025 13:30:00. 50 Economy ticket for £55 per person are available. Travel duration is 16h 40m
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BlaBlaCar Bus19h 40m022:30MadridSur Bus Station18:10LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 10/12/2025 22:30:00 to Perrache Train Station, Lyon (France) arriving at 11/12/2025 18:10:00. 50 Economy ticket for £63 per person are available. Travel duration is 19h 40m
Cheapest Buses Wednesday
What are the fastest trips from Madrid to Lyon?
You can get to Lyon from Madrid in just 16h 40m with a Bus from FlixBus. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
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ALSA17h 0m011:55Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T404:55LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 04/12/2025 11:55:00 to Perrache Bus Stop, Lyon (France) arriving at 05/12/2025 04:55:00. 50 Economy ticket for £49 per person are available. Travel duration is 17h 0m
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BlaBlaCar Bus19h 40m022:30MadridSur Bus Station18:10LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 04/12/2025 22:30:00 to Perrache Train Station, Lyon (France) arriving at 05/12/2025 18:10:00. 50 Economy ticket for £84 per person are available. Travel duration is 19h 40m
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FlixBus20h 0m014:50MadridSur Bus Station10:50LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 04/12/2025 14:50:00 to Perrache Bus Stop, Lyon (France) arriving at 05/12/2025 10:50:00. 50 Economy ticket for £95 per person are available. Travel duration is 20h 0m
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FlixBus20h 20m015:45MadridSur Bus Station12:05LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 04/12/2025 15:45:00 to Perrache Bus Stop, Lyon (France) arriving at 05/12/2025 12:05:00. 50 Economy ticket for £94 per person are available. Travel duration is 20h 20m
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BlaBlaCar Bus24h 10m018:35MadridSur Bus Station18:45LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 04/12/2025 18:35:00 to Perrache Train Station, Lyon (France) arriving at 05/12/2025 18:45:00. 50 Economy ticket for £70 per person are available. Travel duration is 24h 10m
Fastest Buses Thursday
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BlaBlaCar Bus17h 25m008:35MadridSur Bus Station02:00LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 05/12/2025 08:35:00 to Perrache Train Station, Lyon (France) arriving at 06/12/2025 02:00:00. 50 Economy ticket for £47 per person are available. Travel duration is 17h 25m
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ALSA18h 10m010:45Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T404:55LyonPerrache Bus Stop0BasicA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 05/12/2025 10:45:00 to Perrache Bus Stop, Lyon (France) arriving at 06/12/2025 04:55:00. 50 Basic ticket for £57 per person are available. Travel duration is 18h 10m
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ALSA18h 30m010:45Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T405:15LyonPerrache Bus Stop0BasicA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 05/12/2025 10:45:00 to Perrache Bus Stop, Lyon (France) arriving at 06/12/2025 05:15:00. 50 Basic ticket for £57 per person are available. Travel duration is 18h 30m
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BlaBlaCar Bus19h 40m022:30MadridSur Bus Station18:10LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 05/12/2025 22:30:00 to Perrache Train Station, Lyon (France) arriving at 06/12/2025 18:10:00. 50 Economy ticket for £51 per person are available. Travel duration is 19h 40m
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Union Ivkoni23h 0m010:00MadridMendez Alvaro Train Station09:00LyonPerrache Bus Stop0BasicA Bus from Union Ivkoni goes from Mendez Alvaro Train Station, Madrid (Spain) at 05/12/2025 10:00:00 to Perrache Bus Stop, Lyon (France) arriving at 06/12/2025 09:00:00. 50 Basic ticket for £51 per person are available. Travel duration is 23h 0m
Fastest Buses Friday
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FlixBus16h 40m020:50MadridSur Bus Station13:30LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 06/12/2025 20:50:00 to Perrache Bus Stop, Lyon (France) arriving at 07/12/2025 13:30:00. 50 Economy ticket for £58 per person are available. Travel duration is 16h 40m
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ALSA17h 0m011:55Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T404:55LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 06/12/2025 11:55:00 to Perrache Bus Stop, Lyon (France) arriving at 07/12/2025 04:55:00. 50 Economy ticket for £40 per person are available. Travel duration is 17h 0m
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ALSA18h 10m010:45Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T404:55LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 06/12/2025 10:45:00 to Perrache Bus Stop, Lyon (France) arriving at 07/12/2025 04:55:00. 50 Economy ticket for £40 per person are available. Travel duration is 18h 10m
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BlaBlaCar Bus19h 40m022:30MadridSur Bus Station18:10LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 06/12/2025 22:30:00 to Perrache Train Station, Lyon (France) arriving at 07/12/2025 18:10:00. 50 Economy ticket for £56 per person are available. Travel duration is 19h 40m
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BlaBlaCar Bus24h 10m018:35MadridSur Bus Station18:45LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 06/12/2025 18:35:00 to Perrache Train Station, Lyon (France) arriving at 07/12/2025 18:45:00. 50 Economy ticket for £66 per person are available. Travel duration is 24h 10m
Fastest Buses Saturday
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ALSA17h 0m011:55Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T404:55LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 07/12/2025 11:55:00 to Perrache Bus Stop, Lyon (France) arriving at 08/12/2025 04:55:00. 50 Economy ticket for £45 per person are available. Travel duration is 17h 0m
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ALSA19h 30m022:45Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T418:15LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 07/12/2025 22:45:00 to Perrache Bus Stop, Lyon (France) arriving at 08/12/2025 18:15:00. 50 Economy ticket for £54 per person are available. Travel duration is 19h 30m
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Union Ivkoni22h 30m010:00MadridMendez Alvaro Train Station08:30LyonPerrache Bus Stop0BasicA Bus from Union Ivkoni goes from Mendez Alvaro Train Station, Madrid (Spain) at 07/12/2025 10:00:00 to Perrache Bus Stop, Lyon (France) arriving at 08/12/2025 08:30:00. 50 Basic ticket for £51 per person are available. Travel duration is 22h 30m
Fastest Buses Sunday
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FlixBus16h 40m020:50MadridSur Bus Station13:30LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 08/12/2025 20:50:00 to Perrache Bus Stop, Lyon (France) arriving at 09/12/2025 13:30:00. 50 Economy ticket for £56 per person are available. Travel duration is 16h 40m
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ALSA18h 1m000:14Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T418:15LyonPerrache Bus Stop0BasicA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 08/12/2025 00:14:00 to Perrache Bus Stop, Lyon (France) arriving at 08/12/2025 18:15:00. 50 Basic ticket for £52 per person are available. Travel duration is 18h 1m
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ALSA18h 40m010:15Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T404:55LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 08/12/2025 10:15:00 to Perrache Bus Stop, Lyon (France) arriving at 09/12/2025 04:55:00. 50 Economy ticket for £54 per person are available. Travel duration is 18h 40m
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FlixBus20h 20m020:50Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T417:10LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 08/12/2025 20:50:00 to Perrache Bus Stop, Lyon (France) arriving at 09/12/2025 17:10:00. 50 Economy ticket for £72 per person are available. Travel duration is 20h 20m
Fastest Buses Monday
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FlixBus16h 40m020:50MadridSur Bus Station13:30LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 09/12/2025 20:50:00 to Perrache Bus Stop, Lyon (France) arriving at 10/12/2025 13:30:00. 50 Economy ticket for £53 per person are available. Travel duration is 16h 40m
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ALSA18h 30m023:45Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T418:15LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 09/12/2025 23:45:00 to Perrache Bus Stop, Lyon (France) arriving at 10/12/2025 18:15:00. 50 Economy ticket for £45 per person are available. Travel duration is 18h 30m
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ALSA19h 30m022:45Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T418:15LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 09/12/2025 22:45:00 to Perrache Bus Stop, Lyon (France) arriving at 10/12/2025 18:15:00. 50 Economy ticket for £45 per person are available. Travel duration is 19h 30m
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FlixBus20h 0m014:50MadridSur Bus Station10:50LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 09/12/2025 14:50:00 to Perrache Bus Stop, Lyon (France) arriving at 10/12/2025 10:50:00. 50 Economy ticket for £62 per person are available. Travel duration is 20h 0m
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Union Ivkoni22h 0m010:00MadridMendez Alvaro Train Station08:00LyonPerrache Bus Stop0BasicA Bus from Union Ivkoni goes from Mendez Alvaro Train Station, Madrid (Spain) at 09/12/2025 10:00:00 to Perrache Bus Stop, Lyon (France) arriving at 10/12/2025 08:00:00. 50 Basic ticket for £51 per person are available. Travel duration is 22h 0m
Fastest Buses Tuesday
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FlixBus16h 40m020:50MadridSur Bus Station13:30LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 10/12/2025 20:50:00 to Perrache Bus Stop, Lyon (France) arriving at 11/12/2025 13:30:00. 50 Economy ticket for £55 per person are available. Travel duration is 16h 40m
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ALSA17h 0m011:55Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T404:55LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 10/12/2025 11:55:00 to Perrache Bus Stop, Lyon (France) arriving at 11/12/2025 04:55:00. 50 Economy ticket for £45 per person are available. Travel duration is 17h 0m
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BlaBlaCar Bus17h 25m008:35MadridSur Bus Station02:00LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 10/12/2025 08:35:00 to Perrache Train Station, Lyon (France) arriving at 11/12/2025 02:00:00. 50 Economy ticket for £50 per person are available. Travel duration is 17h 25m
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ALSA18h 1m000:14Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T418:15LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 10/12/2025 00:14:00 to Perrache Bus Stop, Lyon (France) arriving at 10/12/2025 18:15:00. 50 Economy ticket for £45 per person are available. Travel duration is 18h 1m
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BlaBlaCar Bus19h 40m022:30MadridSur Bus Station18:10LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 10/12/2025 22:30:00 to Perrache Train Station, Lyon (France) arriving at 11/12/2025 18:10:00. 50 Economy ticket for £63 per person are available. Travel duration is 19h 40m
Fastest Buses Wednesday
Here you will find all operators and timetables for a
Bus from Madrid to Lyon
What are the most popular stations in Madrid and Lyon?
In Madrid, you will usually depart from Atocha Train Station, Chamartin Train Station or Sur Bus Station, while in Lyon you will be arriving at Perrache Bus Stop, Part-Dieu Train Station or Perrache Train Station, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Lyon from Madrid? With 4 connections between 4 Bus and Flight operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Madrid and Lyon, you can pay as low as £40 with a Bus from ALSA.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Bus from FlixBus: you will get to Lyon in just 16h 40m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Madrid and Lyon are ALSA, BlaBlaCar Bus and FlixBus, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Madrid and Lyon is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Delicias or to Caluire-et-Cuire, and look at flights from Adolfo Suárez Madrid-Barajas Airport, and landing at Lyons St. Exupery Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Madrid to Lyon?
The most popular companies between Madrid and Lyon, are ALSA, BlaBlaCar Bus and FlixBus. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: ALSA, BlaBlaCar Bus, FlixBus and 1 more.
All you need to know when you travel from Madrid to Lyon
Check all information on comfort and services on all modes of transports from Madrid to Lyon. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Madrid to Lyon
How can I reach Lyon from Madrid?
Every day, there are on average 4 connections between Bus and Flight, with which you can get to Lyon from Madrid.
How far is Lyon from Madrid?
The distance between Madrid and Lyon is 912.1 km.
What is the most ecofriendly mode of transport between Madrid and Lyon?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 25 kgs of CO2, a train 32 kgs, a car 155 kgs, and a flight 224 kgs.
What is the cheapest mode of transport from Madrid to Lyon?
You can get to Lyon with just £40 by taking a Bus from ALSA.
What is the fastest way to get from Madrid to Lyon?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Lyon in just 16h 40m with a Bus from FlixBus.
More routes to Madrid and to Lyon
Looking for more options? Here you can see the most popular routes to Madrid and to Lyon. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Madrid
- A Coruña to Madrid
- Algeciras to Madrid
- Alicante to Madrid
- Ávila to Madrid
- Barcelona to Madrid
- Benidorm to Madrid
- Bilbao to Madrid
- Cáceres (ES) to Madrid
- Castellón de la Plana to Madrid
- Gandía to Madrid
- Huelva to Madrid
- León to Madrid
- Lisbon to Madrid
- Logroño to Madrid
- Malaga to Madrid
- Ourense to Madrid
- Oviedo to Madrid
- Porto to Madrid
- San Sebastian to Madrid
- Santander to Madrid
- Santiago de Compostela to Madrid
- Segovia to Madrid
- Valencia to Madrid
- Vigo to Madrid
- Trips to Lyon
- Alicante to Lyon
- Barcelona to Lyon
- Bordeaux to Lyon
- Frankfurt am Main to Lyon
- Geneva to Lyon
- Lisbon to Lyon
- Lyons St. Exupery Airport to Lyon
- Marseille Airport to Lyon
- Marseille to Lyon
- Milan to Lyon
- Moulins to Lyon
- Mulhouse to Lyon
- Nuremberg to Lyon
- Paris to Lyon
- Rome to Lyon
- Rouen to Lyon
- Saint-Étienne to Lyon
- Toulouse to Lyon
- Tours to Lyon
- Turin to Lyon
- Valence to Lyon
- Valencia to Lyon
- Venice to Lyon
- Viseu to Lyon

