What is the best way to travel from Madrid to Lyon?
Looking for a trip? Check and compare all the available Flights and Buses to Lyon from Madrid. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 5 available companies to find your perfect trip!
What is the cheapest way to reach Lyon from Madrid?
You can reach Lyon with just £34 by taking a Bus from ALSA, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
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BlaBlaCar Bus19h 40m022:30MadridSur Bus Station18:10LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 04/02/2026 22:30:00 to Perrache Train Station, Lyon (France) arriving at 05/02/2026 18:10:00. 50 Economy ticket for £42 per person are available. Travel duration is 19h 40m
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ALSA17h 0m011:55Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T404:55LyonPerrache Bus Stop0BasicA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 04/02/2026 11:55:00 to Perrache Bus Stop, Lyon (France) arriving at 05/02/2026 04:55:00. 50 Basic ticket for £47 per person are available. Travel duration is 17h 0m
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BlaBlaCar Bus24h 15m018:35MadridSur Bus Station18:50LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 04/02/2026 18:35:00 to Perrache Train Station, Lyon (France) arriving at 05/02/2026 18:50:00. 50 Economy ticket for £47 per person are available. Travel duration is 24h 15m
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Air Nostrum1h 50m021:55Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T423:45Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Air Nostrum goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 04/02/2026 21:55:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 04/02/2026 23:45:00. 50 Economy ticket for £87 per person are available. Travel duration is 1h 50m
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Iberia1h 50m021:55Adolfo Suárez Madrid-Barajas AirportMadrid Airport23:45Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Iberia goes from Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) at 04/02/2026 21:55:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 04/02/2026 23:45:00. 50 Economy ticket for £91 per person are available. Travel duration is 1h 50m
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Pegasus Airlines22h 40m014:55Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T413:35Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Pegasus Airlines goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 04/02/2026 14:55:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 05/02/2026 13:35:00. 50 Economy ticket for £102 per person are available. Travel duration is 22h 40m
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Skyscanner11h 45m012:10Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T423:55Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Skyscanner goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 04/02/2026 12:10:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 04/02/2026 23:55:00. 50 Economy ticket for £103 per person are available. Travel duration is 11h 45m
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Aeronova20h 20m015:05Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T411:25Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Aeronova goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 04/02/2026 15:05:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 05/02/2026 11:25:00. 50 Economy ticket for £104 per person are available. Travel duration is 20h 20m
Cheapest Buses Wednesday
Cheapest Flights Wednesday
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ALSA17h 0m011:55Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T404:55LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 05/02/2026 11:55:00 to Perrache Bus Stop, Lyon (France) arriving at 06/02/2026 04:55:00. 50 Economy ticket for £34 per person are available. Travel duration is 17h 0m
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BlaBlaCar Bus24h 15m018:35MadridSur Bus Station18:50LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 05/02/2026 18:35:00 to Perrache Train Station, Lyon (France) arriving at 06/02/2026 18:50:00. 50 Economy ticket for £41 per person are available. Travel duration is 24h 15m
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BlaBlaCar Bus23h 10m015:30MadridSur Bus Station14:40LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 05/02/2026 15:30:00 to Perrache Train Station, Lyon (France) arriving at 06/02/2026 14:40:00. 50 Economy ticket for £50 per person are available. Travel duration is 23h 10m
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BlaBlaCar Bus19h 40m022:30MadridSur Bus Station18:10LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 05/02/2026 22:30:00 to Perrache Train Station, Lyon (France) arriving at 06/02/2026 18:10:00. 50 Economy ticket for £64 per person are available. Travel duration is 19h 40m
Cheapest Buses Thursday
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ALSA17h 0m011:55Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T404:55LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 06/02/2026 11:55:00 to Perrache Bus Stop, Lyon (France) arriving at 07/02/2026 04:55:00. 50 Economy ticket for £34 per person are available. Travel duration is 17h 0m
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ALSA17h 20m011:55Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T405:15LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 06/02/2026 11:55:00 to Perrache Bus Stop, Lyon (France) arriving at 07/02/2026 05:15:00. 50 Economy ticket for £34 per person are available. Travel duration is 17h 20m
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Union Ivkoni23h 0m010:00MadridMendez Alvaro Train Station09:00LyonPerrache Bus Stop0BasicA Bus from Union Ivkoni goes from Mendez Alvaro Train Station, Madrid (Spain) at 06/02/2026 10:00:00 to Perrache Bus Stop, Lyon (France) arriving at 07/02/2026 09:00:00. 50 Basic ticket for £34 per person are available. Travel duration is 23h 0m
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BlaBlaCar Bus23h 10m015:30MadridSur Bus Station14:40LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 06/02/2026 15:30:00 to Perrache Train Station, Lyon (France) arriving at 07/02/2026 14:40:00. 50 Economy ticket for £45 per person are available. Travel duration is 23h 10m
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BlaBlaCar Bus19h 40m022:30MadridSur Bus Station18:10LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 06/02/2026 22:30:00 to Perrache Train Station, Lyon (France) arriving at 07/02/2026 18:10:00. 50 Economy ticket for £46 per person are available. Travel duration is 19h 40m
Cheapest Buses Friday
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ALSA17h 0m011:55Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T404:55LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 07/02/2026 11:55:00 to Perrache Bus Stop, Lyon (France) arriving at 08/02/2026 04:55:00. 50 Economy ticket for £40 per person are available. Travel duration is 17h 0m
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BlaBlaCar Bus24h 15m018:35MadridSur Bus Station18:50LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 07/02/2026 18:35:00 to Perrache Train Station, Lyon (France) arriving at 08/02/2026 18:50:00. 50 Economy ticket for £40 per person are available. Travel duration is 24h 15m
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BlaBlaCar Bus19h 40m022:30MadridSur Bus Station18:10LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 07/02/2026 22:30:00 to Perrache Train Station, Lyon (France) arriving at 08/02/2026 18:10:00. 50 Economy ticket for £44 per person are available. Travel duration is 19h 40m
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BlaBlaCar Bus23h 10m015:30MadridSur Bus Station14:40LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 07/02/2026 15:30:00 to Perrache Train Station, Lyon (France) arriving at 08/02/2026 14:40:00. 50 Economy ticket for £47 per person are available. Travel duration is 23h 10m
Cheapest Buses Saturday
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ALSA18h 30m023:45Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T418:15LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 08/02/2026 23:45:00 to Perrache Bus Stop, Lyon (France) arriving at 09/02/2026 18:15:00. 50 Economy ticket for £34 per person are available. Travel duration is 18h 30m
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ALSA18h 16m023:59MadridAvenida de América Coach Station18:15LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Avenida de América Coach Station, Madrid (Spain) at 08/02/2026 23:59:00 to Perrache Bus Stop, Lyon (France) arriving at 09/02/2026 18:15:00. 50 Economy ticket for £34 per person are available. Travel duration is 18h 16m
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ALSA17h 0m011:55Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T404:55LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 08/02/2026 11:55:00 to Perrache Bus Stop, Lyon (France) arriving at 09/02/2026 04:55:00. 50 Economy ticket for £40 per person are available. Travel duration is 17h 0m
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BlaBlaCar Bus19h 40m022:30MadridSur Bus Station18:10LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 08/02/2026 22:30:00 to Perrache Train Station, Lyon (France) arriving at 09/02/2026 18:10:00. 50 Economy ticket for £44 per person are available. Travel duration is 19h 40m
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BlaBlaCar Bus24h 15m018:35MadridSur Bus Station18:50LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 08/02/2026 18:35:00 to Perrache Train Station, Lyon (France) arriving at 09/02/2026 18:50:00. 50 Economy ticket for £48 per person are available. Travel duration is 24h 15m
Cheapest Buses Sunday
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ALSA18h 1m000:14Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T418:15LyonPerrache Bus Stop0BasicA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 09/02/2026 00:14:00 to Perrache Bus Stop, Lyon (France) arriving at 09/02/2026 18:15:00. 50 Basic ticket for £43 per person are available. Travel duration is 18h 1m
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ALSA17h 0m011:55Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T404:55LyonPerrache Bus Stop0BasicA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 09/02/2026 11:55:00 to Perrache Bus Stop, Lyon (France) arriving at 10/02/2026 04:55:00. 50 Basic ticket for £43 per person are available. Travel duration is 17h 0m
Cheapest Buses Monday
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ALSA17h 45m011:55Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T405:40LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 10/02/2026 11:55:00 to Perrache Bus Stop, Lyon (France) arriving at 11/02/2026 05:40:00. 50 Economy ticket for £34 per person are available. Travel duration is 17h 45m
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ALSA16h 25m013:15Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T405:40LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 10/02/2026 13:15:00 to Perrache Bus Stop, Lyon (France) arriving at 11/02/2026 05:40:00. 50 Economy ticket for £34 per person are available. Travel duration is 16h 25m
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ALSA19h 30m022:45Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T418:15LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 10/02/2026 22:45:00 to Perrache Bus Stop, Lyon (France) arriving at 11/02/2026 18:15:00. 50 Economy ticket for £34 per person are available. Travel duration is 19h 30m
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ALSA18h 30m023:45Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T418:15LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 10/02/2026 23:45:00 to Perrache Bus Stop, Lyon (France) arriving at 11/02/2026 18:15:00. 50 Economy ticket for £34 per person are available. Travel duration is 18h 30m
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ALSA18h 16m023:59MadridAvenida de América Coach Station18:15LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Avenida de América Coach Station, Madrid (Spain) at 10/02/2026 23:59:00 to Perrache Bus Stop, Lyon (France) arriving at 11/02/2026 18:15:00. 50 Economy ticket for £34 per person are available. Travel duration is 18h 16m
Cheapest Buses Tuesday
What are the fastest trips from Madrid to Lyon?
You can get to Lyon from Madrid in just 1h 50m with a Flight from Air Nostrum. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
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Air Nostrum1h 50m021:55Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T423:45Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Air Nostrum goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 04/02/2026 21:55:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 04/02/2026 23:45:00. 50 Economy ticket for £87 per person are available. Travel duration is 1h 50m
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Iberia1h 50m021:55Adolfo Suárez Madrid-Barajas AirportMadrid Airport23:45Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Iberia goes from Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) at 04/02/2026 21:55:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 04/02/2026 23:45:00. 50 Economy ticket for £91 per person are available. Travel duration is 1h 50m
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Skyscanner11h 45m012:10Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T423:55Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Skyscanner goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 04/02/2026 12:10:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 04/02/2026 23:55:00. 50 Economy ticket for £103 per person are available. Travel duration is 11h 45m
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Aeronova20h 20m015:05Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T411:25Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Aeronova goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 04/02/2026 15:05:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 05/02/2026 11:25:00. 50 Economy ticket for £104 per person are available. Travel duration is 20h 20m
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Pegasus Airlines22h 40m014:55Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T413:35Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Pegasus Airlines goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 04/02/2026 14:55:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 05/02/2026 13:35:00. 50 Economy ticket for £102 per person are available. Travel duration is 22h 40m
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ALSA17h 0m011:55Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T404:55LyonPerrache Bus Stop0BasicA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 04/02/2026 11:55:00 to Perrache Bus Stop, Lyon (France) arriving at 05/02/2026 04:55:00. 50 Basic ticket for £47 per person are available. Travel duration is 17h 0m
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BlaBlaCar Bus19h 40m022:30MadridSur Bus Station18:10LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 04/02/2026 22:30:00 to Perrache Train Station, Lyon (France) arriving at 05/02/2026 18:10:00. 50 Economy ticket for £42 per person are available. Travel duration is 19h 40m
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BlaBlaCar Bus24h 15m018:35MadridSur Bus Station18:50LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 04/02/2026 18:35:00 to Perrache Train Station, Lyon (France) arriving at 05/02/2026 18:50:00. 50 Economy ticket for £47 per person are available. Travel duration is 24h 15m
Fastest Flights Wednesday
Fastest Buses Wednesday
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ALSA17h 0m011:55Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T404:55LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 05/02/2026 11:55:00 to Perrache Bus Stop, Lyon (France) arriving at 06/02/2026 04:55:00. 50 Economy ticket for £34 per person are available. Travel duration is 17h 0m
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BlaBlaCar Bus19h 40m022:30MadridSur Bus Station18:10LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 05/02/2026 22:30:00 to Perrache Train Station, Lyon (France) arriving at 06/02/2026 18:10:00. 50 Economy ticket for £64 per person are available. Travel duration is 19h 40m
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BlaBlaCar Bus23h 10m015:30MadridSur Bus Station14:40LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 05/02/2026 15:30:00 to Perrache Train Station, Lyon (France) arriving at 06/02/2026 14:40:00. 50 Economy ticket for £50 per person are available. Travel duration is 23h 10m
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BlaBlaCar Bus24h 15m018:35MadridSur Bus Station18:50LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 05/02/2026 18:35:00 to Perrache Train Station, Lyon (France) arriving at 06/02/2026 18:50:00. 50 Economy ticket for £41 per person are available. Travel duration is 24h 15m
Fastest Buses Thursday
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ALSA17h 0m011:55Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T404:55LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 06/02/2026 11:55:00 to Perrache Bus Stop, Lyon (France) arriving at 07/02/2026 04:55:00. 50 Economy ticket for £34 per person are available. Travel duration is 17h 0m
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ALSA17h 20m011:55Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T405:15LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 06/02/2026 11:55:00 to Perrache Bus Stop, Lyon (France) arriving at 07/02/2026 05:15:00. 50 Economy ticket for £34 per person are available. Travel duration is 17h 20m
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BlaBlaCar Bus19h 40m022:30MadridSur Bus Station18:10LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 06/02/2026 22:30:00 to Perrache Train Station, Lyon (France) arriving at 07/02/2026 18:10:00. 50 Economy ticket for £46 per person are available. Travel duration is 19h 40m
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Union Ivkoni23h 0m010:00MadridMendez Alvaro Train Station09:00LyonPerrache Bus Stop0BasicA Bus from Union Ivkoni goes from Mendez Alvaro Train Station, Madrid (Spain) at 06/02/2026 10:00:00 to Perrache Bus Stop, Lyon (France) arriving at 07/02/2026 09:00:00. 50 Basic ticket for £34 per person are available. Travel duration is 23h 0m
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BlaBlaCar Bus23h 10m015:30MadridSur Bus Station14:40LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 06/02/2026 15:30:00 to Perrache Train Station, Lyon (France) arriving at 07/02/2026 14:40:00. 50 Economy ticket for £45 per person are available. Travel duration is 23h 10m
Fastest Buses Friday
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ALSA17h 0m011:55Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T404:55LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 07/02/2026 11:55:00 to Perrache Bus Stop, Lyon (France) arriving at 08/02/2026 04:55:00. 50 Economy ticket for £40 per person are available. Travel duration is 17h 0m
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BlaBlaCar Bus19h 40m022:30MadridSur Bus Station18:10LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 07/02/2026 22:30:00 to Perrache Train Station, Lyon (France) arriving at 08/02/2026 18:10:00. 50 Economy ticket for £44 per person are available. Travel duration is 19h 40m
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BlaBlaCar Bus23h 10m015:30MadridSur Bus Station14:40LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 07/02/2026 15:30:00 to Perrache Train Station, Lyon (France) arriving at 08/02/2026 14:40:00. 50 Economy ticket for £47 per person are available. Travel duration is 23h 10m
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BlaBlaCar Bus24h 15m018:35MadridSur Bus Station18:50LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 07/02/2026 18:35:00 to Perrache Train Station, Lyon (France) arriving at 08/02/2026 18:50:00. 50 Economy ticket for £40 per person are available. Travel duration is 24h 15m
Fastest Buses Saturday
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ALSA17h 0m011:55Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T404:55LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 08/02/2026 11:55:00 to Perrache Bus Stop, Lyon (France) arriving at 09/02/2026 04:55:00. 50 Economy ticket for £40 per person are available. Travel duration is 17h 0m
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ALSA18h 16m023:59MadridAvenida de América Coach Station18:15LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Avenida de América Coach Station, Madrid (Spain) at 08/02/2026 23:59:00 to Perrache Bus Stop, Lyon (France) arriving at 09/02/2026 18:15:00. 50 Economy ticket for £34 per person are available. Travel duration is 18h 16m
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ALSA18h 30m023:45Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T418:15LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 08/02/2026 23:45:00 to Perrache Bus Stop, Lyon (France) arriving at 09/02/2026 18:15:00. 50 Economy ticket for £34 per person are available. Travel duration is 18h 30m
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BlaBlaCar Bus19h 40m022:30MadridSur Bus Station18:10LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 08/02/2026 22:30:00 to Perrache Train Station, Lyon (France) arriving at 09/02/2026 18:10:00. 50 Economy ticket for £44 per person are available. Travel duration is 19h 40m
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BlaBlaCar Bus24h 15m018:35MadridSur Bus Station18:50LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 08/02/2026 18:35:00 to Perrache Train Station, Lyon (France) arriving at 09/02/2026 18:50:00. 50 Economy ticket for £48 per person are available. Travel duration is 24h 15m
Fastest Buses Sunday
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ALSA17h 0m011:55Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T404:55LyonPerrache Bus Stop0BasicA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 09/02/2026 11:55:00 to Perrache Bus Stop, Lyon (France) arriving at 10/02/2026 04:55:00. 50 Basic ticket for £43 per person are available. Travel duration is 17h 0m
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ALSA18h 1m000:14Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T418:15LyonPerrache Bus Stop0BasicA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 09/02/2026 00:14:00 to Perrache Bus Stop, Lyon (France) arriving at 09/02/2026 18:15:00. 50 Basic ticket for £43 per person are available. Travel duration is 18h 1m
Fastest Buses Monday
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ALSA16h 25m013:15Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T405:40LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 10/02/2026 13:15:00 to Perrache Bus Stop, Lyon (France) arriving at 11/02/2026 05:40:00. 50 Economy ticket for £34 per person are available. Travel duration is 16h 25m
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ALSA17h 45m011:55Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T405:40LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 10/02/2026 11:55:00 to Perrache Bus Stop, Lyon (France) arriving at 11/02/2026 05:40:00. 50 Economy ticket for £34 per person are available. Travel duration is 17h 45m
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ALSA18h 16m023:59MadridAvenida de América Coach Station18:15LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Avenida de América Coach Station, Madrid (Spain) at 10/02/2026 23:59:00 to Perrache Bus Stop, Lyon (France) arriving at 11/02/2026 18:15:00. 50 Economy ticket for £34 per person are available. Travel duration is 18h 16m
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ALSA18h 30m023:45Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T418:15LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 10/02/2026 23:45:00 to Perrache Bus Stop, Lyon (France) arriving at 11/02/2026 18:15:00. 50 Economy ticket for £34 per person are available. Travel duration is 18h 30m
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ALSA19h 30m022:45Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T418:15LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 10/02/2026 22:45:00 to Perrache Bus Stop, Lyon (France) arriving at 11/02/2026 18:15:00. 50 Economy ticket for £34 per person are available. Travel duration is 19h 30m
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Here you will find all operators and timetables for a
Bus from Madrid to Lyon
What are the most popular stations in Madrid and Lyon?
In Madrid, you will usually depart from Atocha Train Station, Chamartin Train Station or Sur Bus Station, while in Lyon you will be arriving at Perrache Bus Stop, Part-Dieu Train Station or Perrache Train Station, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Lyon from Madrid? With 5 connections between 5 Flight and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Madrid and Lyon, you can pay as low as £34 with a Bus from ALSA.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Air Nostrum: you will get to Lyon in just 1h 50m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Madrid and Lyon are ALSA, BlaBlaCar Bus and Union Ivkoni, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Madrid and Lyon is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Delicias or to Caluire-et-Cuire, and look at flights from Adolfo Suárez Madrid-Barajas Airport, and landing at Lyons St. Exupery Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Madrid to Lyon?
The most popular companies between Madrid and Lyon, are ALSA, BlaBlaCar Bus and Union Ivkoni. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: ALSA, BlaBlaCar Bus and Union Ivkoni
Airlines: Air Nostrum, Iberia, Pegasus Airlines and 2 more.
All you need to know when you travel from Madrid to Lyon
Check all information on comfort and services on all modes of transports from Madrid to Lyon. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Madrid to Lyon
How can I reach Lyon from Madrid?
Every day, there are on average 5 connections between Flight and Bus, with which you can get to Lyon from Madrid.
How far is Lyon from Madrid?
The distance between Madrid and Lyon is 912.1 km.
What is the most ecofriendly mode of transport between Madrid and Lyon?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 25 kgs of CO2, a train 32 kgs, a car 155 kgs, and a flight 224 kgs.
What is the cheapest mode of transport from Madrid to Lyon?
You can get to Lyon with just £34 by taking a Bus from ALSA.
What is the fastest way to get from Madrid to Lyon?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Lyon in just 1h 50m with a Flight from Air Nostrum.
More routes to Madrid and to Lyon
Looking for more options? Here you can see the most popular routes to Madrid and to Lyon. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Madrid
- Algeciras to Madrid
- Alicante to Madrid
- Ávila to Madrid
- Barcelona to Madrid
- Benavente to Madrid
- Bilbao to Madrid
- Castellón de la Plana to Madrid
- Cordoba to Madrid
- Gandía to Madrid
- Huelva to Madrid
- Lisbon to Madrid
- Logroño to Madrid
- Malaga to Madrid
- Murcia to Madrid
- Ourense to Madrid
- Oviedo to Madrid
- Porto to Madrid
- San Sebastian to Madrid
- Santiago de Compostela to Madrid
- Segovia to Madrid
- Seville to Madrid
- Toulouse to Madrid
- Valencia to Madrid
- Vigo to Madrid
- Trips to Lyon
- Caen to Lyon
- Chambery to Lyon
- Clermont-Ferrand to Lyon
- Dijon to Lyon
- Geneva to Lyon
- Girona to Lyon
- Grenoble to Lyon
- Lisbon to Lyon
- London to Lyon
- Montpellier to Lyon
- Nantes to Lyon
- Naples to Lyon
- Nice to Lyon
- Poitiers to Lyon
- Prague to Lyon
- Rome to Lyon
- Sallanches to Lyon
- Strasbourg to Lyon
- Toulon to Lyon
- Turin to Lyon
- Valencia to Lyon
- Venice to Lyon
- Villefranche-sur-Saône to Lyon
- Zurich to Lyon
