What is the best way to travel from Madrid to Lyon?
Looking for a trip? Check and compare all the available Flights, Trains and Buses to Lyon from Madrid. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 5 available companies to find your perfect trip!
What is the cheapest way to reach Lyon from Madrid?
You can reach Lyon with just £28 by taking a Bus from ALSA, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
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ALSA17h 20m011:55Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T405:15LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 10/02/2026 11:55:00 to Perrache Bus Stop, Lyon (France) arriving at 11/02/2026 05:15:00. 50 Economy ticket for £38 per person are available. Travel duration is 17h 20m
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ALSA16h 0m013:15Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T405:15LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 10/02/2026 13:15:00 to Perrache Bus Stop, Lyon (France) arriving at 11/02/2026 05:15:00. 50 Economy ticket for £38 per person are available. Travel duration is 16h 0m
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ALSA17h 0m011:55Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T404:55LyonPerrache Bus Stop0BasicA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 10/02/2026 11:55:00 to Perrache Bus Stop, Lyon (France) arriving at 11/02/2026 04:55:00. 50 Basic ticket for £39 per person are available. Travel duration is 17h 0m
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ALSA19h 30m022:45Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T418:15LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 10/02/2026 22:45:00 to Perrache Bus Stop, Lyon (France) arriving at 11/02/2026 18:15:00. 50 Economy ticket for £40 per person are available. Travel duration is 19h 30m
Cheapest Buses Tuesday
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ALSA16h 45m009:15Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T402:00LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 11/02/2026 09:15:00 to Perrache Bus Stop, Lyon (France) arriving at 12/02/2026 02:00:00. 50 Economy ticket for £28 per person are available. Travel duration is 16h 45m
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ALSA16h 25m020:50Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T413:15LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 11/02/2026 20:50:00 to Perrache Bus Stop, Lyon (France) arriving at 12/02/2026 13:15:00. 50 Economy ticket for £28 per person are available. Travel duration is 16h 25m
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ALSA17h 25m008:35MadridMendez Alvaro Train Station02:00LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Mendez Alvaro Train Station, Madrid (Spain) at 11/02/2026 08:35:00 to Perrache Bus Stop, Lyon (France) arriving at 12/02/2026 02:00:00. 50 Economy ticket for £28 per person are available. Travel duration is 17h 25m
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BlaBlaCar Bus17h 20m008:35MadridSur Bus Station01:55LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 11/02/2026 08:35:00 to Perrache Train Station, Lyon (France) arriving at 12/02/2026 01:55:00. 50 Economy ticket for £47 per person are available. Travel duration is 17h 20m
Cheapest Buses Wednesday
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ALSA16h 45m020:30MadridMendez Alvaro Train Station13:15LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Mendez Alvaro Train Station, Madrid (Spain) at 12/02/2026 20:30:00 to Perrache Bus Stop, Lyon (France) arriving at 13/02/2026 13:15:00. 50 Economy ticket for £28 per person are available. Travel duration is 16h 45m
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ALSA17h 20m011:55Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T405:15LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 12/02/2026 11:55:00 to Perrache Bus Stop, Lyon (France) arriving at 13/02/2026 05:15:00. 50 Economy ticket for £38 per person are available. Travel duration is 17h 20m
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ALSA16h 0m013:15Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T405:15LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 12/02/2026 13:15:00 to Perrache Bus Stop, Lyon (France) arriving at 13/02/2026 05:15:00. 50 Economy ticket for £38 per person are available. Travel duration is 16h 0m
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BlaBlaCar Bus16h 45m020:30MadridSur Bus Station13:15LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 12/02/2026 20:30:00 to Perrache Train Station, Lyon (France) arriving at 13/02/2026 13:15:00. 50 Economy ticket for £57 per person are available. Travel duration is 16h 45m
Cheapest Buses Thursday
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ALSA16h 45m009:15Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T402:00LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 13/02/2026 09:15:00 to Perrache Bus Stop, Lyon (France) arriving at 14/02/2026 02:00:00. 50 Economy ticket for £28 per person are available. Travel duration is 16h 45m
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ALSA17h 25m008:35MadridMendez Alvaro Train Station02:00LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Mendez Alvaro Train Station, Madrid (Spain) at 13/02/2026 08:35:00 to Perrache Bus Stop, Lyon (France) arriving at 14/02/2026 02:00:00. 50 Economy ticket for £28 per person are available. Travel duration is 17h 25m
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ALSA18h 30m010:45Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T405:15LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 13/02/2026 10:45:00 to Perrache Bus Stop, Lyon (France) arriving at 14/02/2026 05:15:00. 50 Economy ticket for £36 per person are available. Travel duration is 18h 30m
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BlaBlaCar Bus17h 20m008:35MadridSur Bus Station01:55LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 13/02/2026 08:35:00 to Perrache Train Station, Lyon (France) arriving at 14/02/2026 01:55:00. 50 Economy ticket for £47 per person are available. Travel duration is 17h 20m
Cheapest Buses Friday
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ALSA16h 45m020:30MadridMendez Alvaro Train Station13:15LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Mendez Alvaro Train Station, Madrid (Spain) at 14/02/2026 20:30:00 to Perrache Bus Stop, Lyon (France) arriving at 15/02/2026 13:15:00. 50 Economy ticket for £28 per person are available. Travel duration is 16h 45m
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ALSA17h 20m011:55Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T405:15LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 14/02/2026 11:55:00 to Perrache Bus Stop, Lyon (France) arriving at 15/02/2026 05:15:00. 50 Economy ticket for £38 per person are available. Travel duration is 17h 20m
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ALSA16h 0m013:15Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T405:15LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 14/02/2026 13:15:00 to Perrache Bus Stop, Lyon (France) arriving at 15/02/2026 05:15:00. 50 Economy ticket for £38 per person are available. Travel duration is 16h 0m
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BlaBlaCar Bus16h 45m020:30MadridSur Bus Station13:15LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 14/02/2026 20:30:00 to Perrache Train Station, Lyon (France) arriving at 15/02/2026 13:15:00. 50 Economy ticket for £65 per person are available. Travel duration is 16h 45m
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Vueling Airlines22h 5m009:30Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T407:35Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Vueling Airlines goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 14/02/2026 09:30:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 15/02/2026 07:35:00. 50 Economy ticket for £84 per person are available. Travel duration is 22h 5m
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Air Arabia Maroc5h 40m017:15Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T422:55Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Air Arabia Maroc goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 14/02/2026 17:15:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 14/02/2026 22:55:00. 50 Economy ticket for £110 per person are available. Travel duration is 5h 40m
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Air Europa9h 50m006:35Adolfo Suárez Madrid-Barajas AirportMadrid Airport16:25Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Air Europa goes from Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) at 14/02/2026 06:35:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 14/02/2026 16:25:00. 50 Economy ticket for £128 per person are available. Travel duration is 9h 50m
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Iberia18h 35m013:00Adolfo Suárez Madrid-Barajas AirportMadrid Airport07:35Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Iberia goes from Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) at 14/02/2026 13:00:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 15/02/2026 07:35:00. 50 Economy ticket for £140 per person are available. Travel duration is 18h 35m
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Iryo14h 16m007:22MadridAtocha Train Station21:38LyonPart-Dieu Train Station0EconomyA Train from Iryo goes from Atocha Train Station, Madrid (Spain) at 14/02/2026 07:22:00 to Part-Dieu Train Station, Lyon (France) arriving at 14/02/2026 21:38:00. 50 Economy ticket for £124 per person are available. Travel duration is 14h 16m
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Iryo12h 48m008:50MadridAtocha Train Station21:38LyonPart-Dieu Train Station0EconomyA Train from Iryo goes from Atocha Train Station, Madrid (Spain) at 14/02/2026 08:50:00 to Part-Dieu Train Station, Lyon (France) arriving at 14/02/2026 21:38:00. 50 Economy ticket for £124 per person are available. Travel duration is 12h 48m
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Iryo12h 16m009:22MadridAtocha Train Station21:38LyonPart-Dieu Train Station0EconomyA Train from Iryo goes from Atocha Train Station, Madrid (Spain) at 14/02/2026 09:22:00 to Part-Dieu Train Station, Lyon (France) arriving at 14/02/2026 21:38:00. 50 Economy ticket for £124 per person are available. Travel duration is 12h 16m
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Iryo10h 16m011:22MadridAtocha Train Station21:38LyonPart-Dieu Train Station0EconomyA Train from Iryo goes from Atocha Train Station, Madrid (Spain) at 14/02/2026 11:22:00 to Part-Dieu Train Station, Lyon (France) arriving at 14/02/2026 21:38:00. 50 Economy ticket for £124 per person are available. Travel duration is 10h 16m
Cheapest Buses Saturday
Cheapest Flights Saturday
Cheapest Trains Saturday
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ALSA16h 25m020:50Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T413:15LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 15/02/2026 20:50:00 to Perrache Bus Stop, Lyon (France) arriving at 16/02/2026 13:15:00. 50 Economy ticket for £34 per person are available. Travel duration is 16h 25m
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ALSA16h 45m020:30MadridMendez Alvaro Train Station13:15LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Mendez Alvaro Train Station, Madrid (Spain) at 15/02/2026 20:30:00 to Perrache Bus Stop, Lyon (France) arriving at 16/02/2026 13:15:00. 50 Economy ticket for £34 per person are available. Travel duration is 16h 45m
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ALSA17h 20m011:55Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T405:15LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 15/02/2026 11:55:00 to Perrache Bus Stop, Lyon (France) arriving at 16/02/2026 05:15:00. 50 Economy ticket for £36 per person are available. Travel duration is 17h 20m
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BlaBlaCar Bus16h 45m020:30MadridSur Bus Station13:15LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 15/02/2026 20:30:00 to Perrache Train Station, Lyon (France) arriving at 16/02/2026 13:15:00. 50 Economy ticket for £47 per person are available. Travel duration is 16h 45m
Cheapest Buses Sunday
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ALSA16h 25m020:50Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T413:15LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 16/02/2026 20:50:00 to Perrache Bus Stop, Lyon (France) arriving at 17/02/2026 13:15:00. 50 Economy ticket for £28 per person are available. Travel duration is 16h 25m
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ALSA16h 45m020:30MadridMendez Alvaro Train Station13:15LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Mendez Alvaro Train Station, Madrid (Spain) at 16/02/2026 20:30:00 to Perrache Bus Stop, Lyon (France) arriving at 17/02/2026 13:15:00. 50 Economy ticket for £28 per person are available. Travel duration is 16h 45m
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ALSA17h 0m011:55Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T404:55LyonPerrache Bus Stop0BasicA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 16/02/2026 11:55:00 to Perrache Bus Stop, Lyon (France) arriving at 17/02/2026 04:55:00. 50 Basic ticket for £39 per person are available. Travel duration is 17h 0m
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BlaBlaCar Bus24h 15m018:35MadridSur Bus Station18:50LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 16/02/2026 18:35:00 to Perrache Train Station, Lyon (France) arriving at 17/02/2026 18:50:00. 50 Economy ticket for £44 per person are available. Travel duration is 24h 15m
Cheapest Buses Monday
What are the fastest trips from Madrid to Lyon?
You can get to Lyon from Madrid in just 5h 40m with a Flight from Air Arabia Maroc. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
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ALSA16h 0m013:15Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T405:15LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 10/02/2026 13:15:00 to Perrache Bus Stop, Lyon (France) arriving at 11/02/2026 05:15:00. 50 Economy ticket for £38 per person are available. Travel duration is 16h 0m
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ALSA17h 0m011:55Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T404:55LyonPerrache Bus Stop0BasicA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 10/02/2026 11:55:00 to Perrache Bus Stop, Lyon (France) arriving at 11/02/2026 04:55:00. 50 Basic ticket for £39 per person are available. Travel duration is 17h 0m
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ALSA17h 20m011:55Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T405:15LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 10/02/2026 11:55:00 to Perrache Bus Stop, Lyon (France) arriving at 11/02/2026 05:15:00. 50 Economy ticket for £38 per person are available. Travel duration is 17h 20m
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ALSA18h 30m023:45Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T418:15LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 10/02/2026 23:45:00 to Perrache Bus Stop, Lyon (France) arriving at 11/02/2026 18:15:00. 50 Economy ticket for £40 per person are available. Travel duration is 18h 30m
Fastest Buses Tuesday
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ALSA16h 25m020:50Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T413:15LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 11/02/2026 20:50:00 to Perrache Bus Stop, Lyon (France) arriving at 12/02/2026 13:15:00. 50 Economy ticket for £28 per person are available. Travel duration is 16h 25m
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ALSA16h 45m009:15Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T402:00LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 11/02/2026 09:15:00 to Perrache Bus Stop, Lyon (France) arriving at 12/02/2026 02:00:00. 50 Economy ticket for £28 per person are available. Travel duration is 16h 45m
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BlaBlaCar Bus16h 45m020:30MadridSur Bus Station13:15LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 11/02/2026 20:30:00 to Perrache Train Station, Lyon (France) arriving at 12/02/2026 13:15:00. 50 Economy ticket for £47 per person are available. Travel duration is 16h 45m
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BlaBlaCar Bus17h 20m008:35MadridSur Bus Station01:55LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 11/02/2026 08:35:00 to Perrache Train Station, Lyon (France) arriving at 12/02/2026 01:55:00. 50 Economy ticket for £47 per person are available. Travel duration is 17h 20m
Fastest Buses Wednesday
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ALSA16h 0m013:15Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T405:15LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 12/02/2026 13:15:00 to Perrache Bus Stop, Lyon (France) arriving at 13/02/2026 05:15:00. 50 Economy ticket for £38 per person are available. Travel duration is 16h 0m
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ALSA16h 45m020:30MadridMendez Alvaro Train Station13:15LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Mendez Alvaro Train Station, Madrid (Spain) at 12/02/2026 20:30:00 to Perrache Bus Stop, Lyon (France) arriving at 13/02/2026 13:15:00. 50 Economy ticket for £28 per person are available. Travel duration is 16h 45m
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BlaBlaCar Bus16h 45m020:30MadridSur Bus Station13:15LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 12/02/2026 20:30:00 to Perrache Train Station, Lyon (France) arriving at 13/02/2026 13:15:00. 50 Economy ticket for £57 per person are available. Travel duration is 16h 45m
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ALSA17h 20m011:55Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T405:15LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 12/02/2026 11:55:00 to Perrache Bus Stop, Lyon (France) arriving at 13/02/2026 05:15:00. 50 Economy ticket for £38 per person are available. Travel duration is 17h 20m
Fastest Buses Thursday
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ALSA16h 45m009:15Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T402:00LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 13/02/2026 09:15:00 to Perrache Bus Stop, Lyon (France) arriving at 14/02/2026 02:00:00. 50 Economy ticket for £28 per person are available. Travel duration is 16h 45m
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BlaBlaCar Bus16h 45m020:30MadridSur Bus Station13:15LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 13/02/2026 20:30:00 to Perrache Train Station, Lyon (France) arriving at 14/02/2026 13:15:00. 50 Economy ticket for £61 per person are available. Travel duration is 16h 45m
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BlaBlaCar Bus17h 20m008:35MadridSur Bus Station01:55LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 13/02/2026 08:35:00 to Perrache Train Station, Lyon (France) arriving at 14/02/2026 01:55:00. 50 Economy ticket for £47 per person are available. Travel duration is 17h 20m
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ALSA17h 25m008:35MadridMendez Alvaro Train Station02:00LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Mendez Alvaro Train Station, Madrid (Spain) at 13/02/2026 08:35:00 to Perrache Bus Stop, Lyon (France) arriving at 14/02/2026 02:00:00. 50 Economy ticket for £28 per person are available. Travel duration is 17h 25m
Fastest Buses Friday
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Air Arabia Maroc5h 40m017:15Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T422:55Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Air Arabia Maroc goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 14/02/2026 17:15:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 14/02/2026 22:55:00. 50 Economy ticket for £110 per person are available. Travel duration is 5h 40m
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Air Europa9h 50m006:35Adolfo Suárez Madrid-Barajas AirportMadrid Airport16:25Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Air Europa goes from Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) at 14/02/2026 06:35:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 14/02/2026 16:25:00. 50 Economy ticket for £128 per person are available. Travel duration is 9h 50m
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Iberia18h 35m013:00Adolfo Suárez Madrid-Barajas AirportMadrid Airport07:35Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Iberia goes from Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) at 14/02/2026 13:00:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 15/02/2026 07:35:00. 50 Economy ticket for £140 per person are available. Travel duration is 18h 35m
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Vueling Airlines22h 5m009:30Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T407:35Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Vueling Airlines goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 14/02/2026 09:30:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 15/02/2026 07:35:00. 50 Economy ticket for £84 per person are available. Travel duration is 22h 5m
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Iryo9h 16m012:22MadridAtocha Train Station21:38LyonPart-Dieu Train Station0EconomyA Train from Iryo goes from Atocha Train Station, Madrid (Spain) at 14/02/2026 12:22:00 to Part-Dieu Train Station, Lyon (France) arriving at 14/02/2026 21:38:00. 50 Economy ticket for £124 per person are available. Travel duration is 9h 16m
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Iryo10h 16m011:22MadridAtocha Train Station21:38LyonPart-Dieu Train Station0EconomyA Train from Iryo goes from Atocha Train Station, Madrid (Spain) at 14/02/2026 11:22:00 to Part-Dieu Train Station, Lyon (France) arriving at 14/02/2026 21:38:00. 50 Economy ticket for £124 per person are available. Travel duration is 10h 16m
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Iryo12h 16m009:22MadridAtocha Train Station21:38LyonPart-Dieu Train Station0EconomyA Train from Iryo goes from Atocha Train Station, Madrid (Spain) at 14/02/2026 09:22:00 to Part-Dieu Train Station, Lyon (France) arriving at 14/02/2026 21:38:00. 50 Economy ticket for £124 per person are available. Travel duration is 12h 16m
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Iryo12h 48m008:50MadridAtocha Train Station21:38LyonPart-Dieu Train Station0EconomyA Train from Iryo goes from Atocha Train Station, Madrid (Spain) at 14/02/2026 08:50:00 to Part-Dieu Train Station, Lyon (France) arriving at 14/02/2026 21:38:00. 50 Economy ticket for £124 per person are available. Travel duration is 12h 48m
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ALSA16h 0m013:15Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T405:15LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 14/02/2026 13:15:00 to Perrache Bus Stop, Lyon (France) arriving at 15/02/2026 05:15:00. 50 Economy ticket for £38 per person are available. Travel duration is 16h 0m
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ALSA16h 45m020:30MadridMendez Alvaro Train Station13:15LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Mendez Alvaro Train Station, Madrid (Spain) at 14/02/2026 20:30:00 to Perrache Bus Stop, Lyon (France) arriving at 15/02/2026 13:15:00. 50 Economy ticket for £28 per person are available. Travel duration is 16h 45m
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BlaBlaCar Bus16h 45m020:30MadridSur Bus Station13:15LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 14/02/2026 20:30:00 to Perrache Train Station, Lyon (France) arriving at 15/02/2026 13:15:00. 50 Economy ticket for £65 per person are available. Travel duration is 16h 45m
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ALSA17h 20m011:55Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T405:15LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 14/02/2026 11:55:00 to Perrache Bus Stop, Lyon (France) arriving at 15/02/2026 05:15:00. 50 Economy ticket for £38 per person are available. Travel duration is 17h 20m
Fastest Flights Saturday
Fastest Trains Saturday
Fastest Buses Saturday
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ALSA16h 25m020:50Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T413:15LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 15/02/2026 20:50:00 to Perrache Bus Stop, Lyon (France) arriving at 16/02/2026 13:15:00. 50 Economy ticket for £34 per person are available. Travel duration is 16h 25m
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ALSA16h 45m020:30MadridMendez Alvaro Train Station13:15LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Mendez Alvaro Train Station, Madrid (Spain) at 15/02/2026 20:30:00 to Perrache Bus Stop, Lyon (France) arriving at 16/02/2026 13:15:00. 50 Economy ticket for £34 per person are available. Travel duration is 16h 45m
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BlaBlaCar Bus16h 45m020:30MadridSur Bus Station13:15LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 15/02/2026 20:30:00 to Perrache Train Station, Lyon (France) arriving at 16/02/2026 13:15:00. 50 Economy ticket for £47 per person are available. Travel duration is 16h 45m
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ALSA17h 20m011:55Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T405:15LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 15/02/2026 11:55:00 to Perrache Bus Stop, Lyon (France) arriving at 16/02/2026 05:15:00. 50 Economy ticket for £36 per person are available. Travel duration is 17h 20m
Fastest Buses Sunday
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ALSA16h 25m020:50Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T413:15LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 16/02/2026 20:50:00 to Perrache Bus Stop, Lyon (France) arriving at 17/02/2026 13:15:00. 50 Economy ticket for £28 per person are available. Travel duration is 16h 25m
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ALSA16h 45m020:30MadridMendez Alvaro Train Station13:15LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Mendez Alvaro Train Station, Madrid (Spain) at 16/02/2026 20:30:00 to Perrache Bus Stop, Lyon (France) arriving at 17/02/2026 13:15:00. 50 Economy ticket for £28 per person are available. Travel duration is 16h 45m
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ALSA17h 0m011:55Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T404:55LyonPerrache Bus Stop0BasicA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 16/02/2026 11:55:00 to Perrache Bus Stop, Lyon (France) arriving at 17/02/2026 04:55:00. 50 Basic ticket for £39 per person are available. Travel duration is 17h 0m
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BlaBlaCar Bus21h 20m020:30MadridSur Bus Station17:50LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 16/02/2026 20:30:00 to Perrache Train Station, Lyon (France) arriving at 17/02/2026 17:50:00. 50 Economy ticket for £46 per person are available. Travel duration is 21h 20m
Fastest Buses Monday
Here you will find all operators and timetables for a
Bus from Madrid to Lyon
What are the most popular stations in Madrid and Lyon?
In Madrid, you will usually depart from Atocha Train Station, Sur Bus Station or Chamartin Train Station, while in Lyon you will be arriving at Perrache Bus Stop, Part-Dieu Train Station or Perrache Train Station, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Lyon from Madrid? With 6 connections between 5 Flight, Train and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Madrid and Lyon, you can pay as low as £28 with a Bus from ALSA.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Air Arabia Maroc: you will get to Lyon in just 5h 40m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Madrid and Lyon are ALSA, BlaBlaCar Bus and Iryo, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Madrid and Lyon is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Delicias or to Caluire-et-Cuire, and look at flights from Adolfo Suárez Madrid-Barajas Airport, and landing at Lyons St. Exupery Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Madrid to Lyon?
The most popular companies between Madrid and Lyon, are ALSA, BlaBlaCar Bus and Iryo. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: ALSA and BlaBlaCar Bus
Train companies: Iryo
Airlines: Vueling Airlines, Air Arabia Maroc, Air Europa and 2 more.
All you need to know when you travel from Madrid to Lyon
Check all information on comfort and services on all modes of transports from Madrid to Lyon. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Madrid to Lyon
How can I reach Lyon from Madrid?
Every day, there are on average 6 connections between Flight, Train and Bus, with which you can get to Lyon from Madrid.
How far is Lyon from Madrid?
The distance between Madrid and Lyon is 912.1 km.
What is the most ecofriendly mode of transport between Madrid and Lyon?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 25 kgs of CO2, a train 32 kgs, a car 155 kgs, and a flight 224 kgs.
What is the cheapest mode of transport from Madrid to Lyon?
You can get to Lyon with just £28 by taking a Bus from ALSA.
What is the fastest way to get from Madrid to Lyon?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Lyon in just 5h 40m with a Flight from Air Arabia Maroc.
More routes to Madrid and to Lyon
Looking for more options? Here you can see the most popular routes to Madrid and to Lyon. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Madrid
- Algeciras to Madrid
- Alicante to Madrid
- Ávila to Madrid
- Barcelona to Madrid
- Benavente to Madrid
- Bilbao to Madrid
- Castellón de la Plana to Madrid
- Cordoba to Madrid
- Gandía to Madrid
- Guadalajara to Madrid
- Huelva to Madrid
- Lisbon to Madrid
- Logroño to Madrid
- Malaga to Madrid
- Ourense to Madrid
- Oviedo to Madrid
- Porto to Madrid
- San Sebastian to Madrid
- Santiago de Compostela to Madrid
- Segovia to Madrid
- Seville to Madrid
- Toulouse to Madrid
- Valencia to Madrid
- Vigo to Madrid
- Trips to Lyon
- Bandol to Lyon
- Bologna to Lyon
- Caen to Lyon
- Colmar to Lyon
- Dijon to Lyon
- Geneva to Lyon
- Grenoble to Lyon
- Lisbon to Lyon
- London to Lyon
- Marseille to Lyon
- Memmingen to Lyon
- Nantes to Lyon
- Naples to Lyon
- Nice to Lyon
- Perpignan to Lyon
- Poitiers to Lyon
- Prague to Lyon
- Rome to Lyon
- Strasbourg to Lyon
- Toulon to Lyon
- Toulouse to Lyon
- Turin to Lyon
- Valencia to Lyon
- Zurich to Lyon
