What is the best way to travel from Madrid to Lyon?
Looking for a trip? Check and compare all the available Buses, Trains and Flights to Lyon from Madrid. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 7 available companies to find your perfect trip!
What is the cheapest way to reach Lyon from Madrid?
You can reach Lyon with just £41 by taking a Bus from BlaBlaCar Bus, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
-
ALSA18h 10m010:45Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T404:55LyonPerrache Bus Stop0BasicA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 20/12/2025 10:45:00 to Perrache Bus Stop, Lyon (France) arriving at 21/12/2025 04:55:00. 50 Basic ticket for £57 per person are available. Travel duration is 18h 10m
-
ALSA17h 0m011:55Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T404:55LyonPerrache Bus Stop0BasicA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 20/12/2025 11:55:00 to Perrache Bus Stop, Lyon (France) arriving at 21/12/2025 04:55:00. 50 Basic ticket for £57 per person are available. Travel duration is 17h 0m
-
FlixBus16h 40m020:50MadridSur Bus Station13:30LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 20/12/2025 20:50:00 to Perrache Bus Stop, Lyon (France) arriving at 21/12/2025 13:30:00. 50 Economy ticket for £60 per person are available. Travel duration is 16h 40m
-
FlixBus16h 40m021:55MadridSur Bus Station14:35LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 20/12/2025 21:55:00 to Perrache Bus Stop, Lyon (France) arriving at 21/12/2025 14:35:00. 50 Economy ticket for £60 per person are available. Travel duration is 16h 40m
Cheapest Buses Saturday
-
BlaBlaCar Bus17h 40m006:30MadridSur Bus Station00:10LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 21/12/2025 06:30:00 to Perrache Train Station, Lyon (France) arriving at 22/12/2025 00:10:00. 50 Economy ticket for £43 per person are available. Travel duration is 17h 40m
-
ALSA17h 0m011:55Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T404:55LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 21/12/2025 11:55:00 to Perrache Bus Stop, Lyon (France) arriving at 22/12/2025 04:55:00. 50 Economy ticket for £49 per person are available. Travel duration is 17h 0m
-
BlaBlaCar Bus17h 25m008:35MadridSur Bus Station02:00LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 21/12/2025 08:35:00 to Perrache Train Station, Lyon (France) arriving at 22/12/2025 02:00:00. 50 Economy ticket for £57 per person are available. Travel duration is 17h 25m
-
FlixBus16h 40m021:55MadridSur Bus Station14:35LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 21/12/2025 21:55:00 to Perrache Bus Stop, Lyon (France) arriving at 22/12/2025 14:35:00. 50 Economy ticket for £61 per person are available. Travel duration is 16h 40m
Cheapest Buses Sunday
-
BlaBlaCar Bus18h 40m006:30MadridSur Bus Station01:10LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 22/12/2025 06:30:00 to Perrache Train Station, Lyon (France) arriving at 23/12/2025 01:10:00. 50 Economy ticket for £41 per person are available. Travel duration is 18h 40m
-
ALSA18h 1m000:14Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T418:15LyonPerrache Bus Stop0BasicA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 22/12/2025 00:14:00 to Perrache Bus Stop, Lyon (France) arriving at 22/12/2025 18:15:00. 50 Basic ticket for £52 per person are available. Travel duration is 18h 1m
-
ALSA17h 0m011:55Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T404:55LyonPerrache Bus Stop0BasicA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 22/12/2025 11:55:00 to Perrache Bus Stop, Lyon (France) arriving at 23/12/2025 04:55:00. 50 Basic ticket for £57 per person are available. Travel duration is 17h 0m
-
BlaBlaCar Bus16h 45m020:30MadridSur Bus Station13:15LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 22/12/2025 20:30:00 to Perrache Train Station, Lyon (France) arriving at 23/12/2025 13:15:00. 50 Economy ticket for £79 per person are available. Travel duration is 16h 45m
-
Iryo15h 29m006:09MadridAtocha Train Station21:38LyonPart-Dieu Train Station0EconomyA Train from Iryo goes from Atocha Train Station, Madrid (Spain) at 22/12/2025 06:09:00 to Part-Dieu Train Station, Lyon (France) arriving at 22/12/2025 21:38:00. 50 Economy ticket for £160 per person are available. Travel duration is 15h 29m
-
Iryo12h 48m008:50MadridAtocha Train Station21:38LyonPart-Dieu Train Station0EconomyA Train from Iryo goes from Atocha Train Station, Madrid (Spain) at 22/12/2025 08:50:00 to Part-Dieu Train Station, Lyon (France) arriving at 22/12/2025 21:38:00. 50 Economy ticket for £164 per person are available. Travel duration is 12h 48m
-
Iryo10h 16m011:22MadridAtocha Train Station21:38LyonPart-Dieu Train Station0EconomyA Train from Iryo goes from Atocha Train Station, Madrid (Spain) at 22/12/2025 11:22:00 to Part-Dieu Train Station, Lyon (France) arriving at 22/12/2025 21:38:00. 50 Economy ticket for £166 per person are available. Travel duration is 10h 16m
-
Iryo9h 16m012:22MadridAtocha Train Station21:38LyonPart-Dieu Train Station0EconomyA Train from Iryo goes from Atocha Train Station, Madrid (Spain) at 22/12/2025 12:22:00 to Part-Dieu Train Station, Lyon (France) arriving at 22/12/2025 21:38:00. 50 Economy ticket for £166 per person are available. Travel duration is 9h 16m
Cheapest Buses Monday
Cheapest Trains Monday
-
ALSA17h 10m011:45Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T404:55LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 23/12/2025 11:45:00 to Perrache Bus Stop, Lyon (France) arriving at 24/12/2025 04:55:00. 50 Economy ticket for £45 per person are available. Travel duration is 17h 10m
-
ALSA17h 0m011:55Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T404:55LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 23/12/2025 11:55:00 to Perrache Bus Stop, Lyon (France) arriving at 24/12/2025 04:55:00. 50 Economy ticket for £45 per person are available. Travel duration is 17h 0m
-
BlaBlaCar Bus16h 45m020:30MadridSur Bus Station13:15LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 23/12/2025 20:30:00 to Perrache Train Station, Lyon (France) arriving at 24/12/2025 13:15:00. 50 Economy ticket for £57 per person are available. Travel duration is 16h 45m
-
Union Ivkoni22h 0m010:00MadridMendez Alvaro Train Station08:00LyonPerrache Bus Stop0BasicA Bus from Union Ivkoni goes from Mendez Alvaro Train Station, Madrid (Spain) at 23/12/2025 10:00:00 to Perrache Bus Stop, Lyon (France) arriving at 24/12/2025 08:00:00. 50 Basic ticket for £58 per person are available. Travel duration is 22h 0m
Cheapest Buses Tuesday
-
FlixBus21h 0m019:05MadridSur Bus Station16:05LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 24/12/2025 19:05:00 to Perrache Bus Stop, Lyon (France) arriving at 25/12/2025 16:05:00. 50 Economy ticket for £42 per person are available. Travel duration is 21h 0m
-
BlaBlaCar Bus16h 45m020:30MadridSur Bus Station13:15LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 24/12/2025 20:30:00 to Perrache Train Station, Lyon (France) arriving at 25/12/2025 13:15:00. 50 Economy ticket for £43 per person are available. Travel duration is 16h 45m
-
ALSA18h 1m000:14Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T418:15LyonPerrache Bus Stop0BasicA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 24/12/2025 00:14:00 to Perrache Bus Stop, Lyon (France) arriving at 24/12/2025 18:15:00. 50 Basic ticket for £52 per person are available. Travel duration is 18h 1m
-
FlixBus20h 20m020:50Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T417:10LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 24/12/2025 20:50:00 to Perrache Bus Stop, Lyon (France) arriving at 25/12/2025 17:10:00. 50 Economy ticket for £53 per person are available. Travel duration is 20h 20m
Cheapest Buses Wednesday
-
Air Europa13h 20m010:35Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T423:55Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Air Europa goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 25/12/2025 10:35:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 25/12/2025 23:55:00. 50 Economy ticket for £49 per person are available. Travel duration is 13h 20m
-
Air Nostrum1h 50m021:55Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T423:45Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Air Nostrum goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 25/12/2025 21:55:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 25/12/2025 23:45:00. 50 Economy ticket for £52 per person are available. Travel duration is 1h 50m
-
TAP Portugal5h 25m007:40Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T413:05Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from TAP Portugal goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 25/12/2025 07:40:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 25/12/2025 13:05:00. 50 Economy ticket for £71 per person are available. Travel duration is 5h 25m
-
Air France5h 5m006:00Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T411:05Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Air France goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 25/12/2025 06:00:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 25/12/2025 11:05:00. 50 Economy ticket for £92 per person are available. Travel duration is 5h 5m
-
BlaBlaCar Bus16h 45m020:30MadridSur Bus Station13:15LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 25/12/2025 20:30:00 to Perrache Train Station, Lyon (France) arriving at 26/12/2025 13:15:00. 50 Economy ticket for £53 per person are available. Travel duration is 16h 45m
-
FlixBus19h 50m015:45MadridSur Bus Station11:35LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 25/12/2025 15:45:00 to Perrache Bus Stop, Lyon (France) arriving at 26/12/2025 11:35:00. 50 Economy ticket for £54 per person are available. Travel duration is 19h 50m
-
FlixBus16h 40m020:50MadridSur Bus Station13:30LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 25/12/2025 20:50:00 to Perrache Bus Stop, Lyon (France) arriving at 26/12/2025 13:30:00. 50 Economy ticket for £54 per person are available. Travel duration is 16h 40m
-
FlixBus20h 20m015:45MadridSur Bus Station12:05LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 25/12/2025 15:45:00 to Perrache Bus Stop, Lyon (France) arriving at 26/12/2025 12:05:00. 50 Economy ticket for £55 per person are available. Travel duration is 20h 20m
Cheapest Flights Thursday
Cheapest Buses Thursday
-
BlaBlaCar Bus17h 25m008:35MadridSur Bus Station02:00LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 26/12/2025 08:35:00 to Perrache Train Station, Lyon (France) arriving at 27/12/2025 02:00:00. 50 Economy ticket for £57 per person are available. Travel duration is 17h 25m
-
ALSA17h 20m011:55Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T405:15LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 26/12/2025 11:55:00 to Perrache Bus Stop, Lyon (France) arriving at 27/12/2025 05:15:00. 50 Economy ticket for £58 per person are available. Travel duration is 17h 20m
-
ALSA17h 0m011:55Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T404:55LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 26/12/2025 11:55:00 to Perrache Bus Stop, Lyon (France) arriving at 27/12/2025 04:55:00. 50 Economy ticket for £58 per person are available. Travel duration is 17h 0m
-
Union Ivkoni23h 0m010:00MadridMendez Alvaro Train Station09:00LyonPerrache Bus Stop0BasicA Bus from Union Ivkoni goes from Mendez Alvaro Train Station, Madrid (Spain) at 26/12/2025 10:00:00 to Perrache Bus Stop, Lyon (France) arriving at 27/12/2025 09:00:00. 50 Basic ticket for £65 per person are available. Travel duration is 23h 0m
Cheapest Buses Friday
What are the fastest trips from Madrid to Lyon?
You can get to Lyon from Madrid in just 1h 50m with a Flight from Air Nostrum. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
-
FlixBus16h 40m020:50MadridSur Bus Station13:30LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 20/12/2025 20:50:00 to Perrache Bus Stop, Lyon (France) arriving at 21/12/2025 13:30:00. 50 Economy ticket for £60 per person are available. Travel duration is 16h 40m
-
FlixBus16h 40m021:55MadridSur Bus Station14:35LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 20/12/2025 21:55:00 to Perrache Bus Stop, Lyon (France) arriving at 21/12/2025 14:35:00. 50 Economy ticket for £60 per person are available. Travel duration is 16h 40m
-
BlaBlaCar Bus16h 45m020:30MadridSur Bus Station13:15LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 20/12/2025 20:30:00 to Perrache Train Station, Lyon (France) arriving at 21/12/2025 13:15:00. 50 Economy ticket for £61 per person are available. Travel duration is 16h 45m
-
ALSA17h 0m011:55Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T404:55LyonPerrache Bus Stop0BasicA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 20/12/2025 11:55:00 to Perrache Bus Stop, Lyon (France) arriving at 21/12/2025 04:55:00. 50 Basic ticket for £57 per person are available. Travel duration is 17h 0m
Fastest Buses Saturday
-
FlixBus16h 40m021:55MadridSur Bus Station14:35LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 21/12/2025 21:55:00 to Perrache Bus Stop, Lyon (France) arriving at 22/12/2025 14:35:00. 50 Economy ticket for £61 per person are available. Travel duration is 16h 40m
-
ALSA17h 0m011:55Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T404:55LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 21/12/2025 11:55:00 to Perrache Bus Stop, Lyon (France) arriving at 22/12/2025 04:55:00. 50 Economy ticket for £49 per person are available. Travel duration is 17h 0m
-
BlaBlaCar Bus17h 25m008:35MadridSur Bus Station02:00LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 21/12/2025 08:35:00 to Perrache Train Station, Lyon (France) arriving at 22/12/2025 02:00:00. 50 Economy ticket for £57 per person are available. Travel duration is 17h 25m
-
BlaBlaCar Bus17h 40m006:30MadridSur Bus Station00:10LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 21/12/2025 06:30:00 to Perrache Train Station, Lyon (France) arriving at 22/12/2025 00:10:00. 50 Economy ticket for £43 per person are available. Travel duration is 17h 40m
Fastest Buses Sunday
-
Iryo9h 16m012:22MadridAtocha Train Station21:38LyonPart-Dieu Train Station0EconomyA Train from Iryo goes from Atocha Train Station, Madrid (Spain) at 22/12/2025 12:22:00 to Part-Dieu Train Station, Lyon (France) arriving at 22/12/2025 21:38:00. 50 Economy ticket for £166 per person are available. Travel duration is 9h 16m
-
Iryo10h 16m011:22MadridAtocha Train Station21:38LyonPart-Dieu Train Station0EconomyA Train from Iryo goes from Atocha Train Station, Madrid (Spain) at 22/12/2025 11:22:00 to Part-Dieu Train Station, Lyon (France) arriving at 22/12/2025 21:38:00. 50 Economy ticket for £166 per person are available. Travel duration is 10h 16m
-
Iryo11h 41m009:57MadridAtocha Train Station21:38LyonPart-Dieu Train Station0EconomyA Train from Iryo goes from Atocha Train Station, Madrid (Spain) at 22/12/2025 09:57:00 to Part-Dieu Train Station, Lyon (France) arriving at 22/12/2025 21:38:00. 50 Economy ticket for £172 per person are available. Travel duration is 11h 41m
-
Iryo12h 48m008:50MadridAtocha Train Station21:38LyonPart-Dieu Train Station0EconomyA Train from Iryo goes from Atocha Train Station, Madrid (Spain) at 22/12/2025 08:50:00 to Part-Dieu Train Station, Lyon (France) arriving at 22/12/2025 21:38:00. 50 Economy ticket for £164 per person are available. Travel duration is 12h 48m
-
FlixBus16h 40m021:55MadridSur Bus Station14:35LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 22/12/2025 21:55:00 to Perrache Bus Stop, Lyon (France) arriving at 23/12/2025 14:35:00. 50 Economy ticket for £81 per person are available. Travel duration is 16h 40m
-
BlaBlaCar Bus16h 45m020:30MadridSur Bus Station13:15LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 22/12/2025 20:30:00 to Perrache Train Station, Lyon (France) arriving at 23/12/2025 13:15:00. 50 Economy ticket for £79 per person are available. Travel duration is 16h 45m
-
ALSA17h 0m011:55Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T404:55LyonPerrache Bus Stop0BasicA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 22/12/2025 11:55:00 to Perrache Bus Stop, Lyon (France) arriving at 23/12/2025 04:55:00. 50 Basic ticket for £57 per person are available. Travel duration is 17h 0m
-
ALSA18h 1m000:14Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T418:15LyonPerrache Bus Stop0BasicA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 22/12/2025 00:14:00 to Perrache Bus Stop, Lyon (France) arriving at 22/12/2025 18:15:00. 50 Basic ticket for £52 per person are available. Travel duration is 18h 1m
Fastest Trains Monday
Fastest Buses Monday
-
FlixBus16h 40m021:55MadridSur Bus Station14:35LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 23/12/2025 21:55:00 to Perrache Bus Stop, Lyon (France) arriving at 24/12/2025 14:35:00. 50 Economy ticket for £60 per person are available. Travel duration is 16h 40m
-
BlaBlaCar Bus16h 45m020:30MadridSur Bus Station13:15LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 23/12/2025 20:30:00 to Perrache Train Station, Lyon (France) arriving at 24/12/2025 13:15:00. 50 Economy ticket for £57 per person are available. Travel duration is 16h 45m
-
ALSA17h 0m011:55Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T404:55LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 23/12/2025 11:55:00 to Perrache Bus Stop, Lyon (France) arriving at 24/12/2025 04:55:00. 50 Economy ticket for £45 per person are available. Travel duration is 17h 0m
-
ALSA17h 10m011:45Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T404:55LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 23/12/2025 11:45:00 to Perrache Bus Stop, Lyon (France) arriving at 24/12/2025 04:55:00. 50 Economy ticket for £45 per person are available. Travel duration is 17h 10m
Fastest Buses Tuesday
-
BlaBlaCar Bus16h 45m020:30MadridSur Bus Station13:15LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 24/12/2025 20:30:00 to Perrache Train Station, Lyon (France) arriving at 25/12/2025 13:15:00. 50 Economy ticket for £43 per person are available. Travel duration is 16h 45m
-
ALSA18h 1m000:14Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T418:15LyonPerrache Bus Stop0BasicA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 24/12/2025 00:14:00 to Perrache Bus Stop, Lyon (France) arriving at 24/12/2025 18:15:00. 50 Basic ticket for £52 per person are available. Travel duration is 18h 1m
-
FlixBus20h 20m020:50Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T417:10LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 24/12/2025 20:50:00 to Perrache Bus Stop, Lyon (France) arriving at 25/12/2025 17:10:00. 50 Economy ticket for £53 per person are available. Travel duration is 20h 20m
-
FlixBus21h 0m019:05MadridSur Bus Station16:05LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 24/12/2025 19:05:00 to Perrache Bus Stop, Lyon (France) arriving at 25/12/2025 16:05:00. 50 Economy ticket for £42 per person are available. Travel duration is 21h 0m
Fastest Buses Wednesday
-
Air Nostrum1h 50m021:55Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T423:45Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Air Nostrum goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 25/12/2025 21:55:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 25/12/2025 23:45:00. 50 Economy ticket for £52 per person are available. Travel duration is 1h 50m
-
Brussels Airlines4h 45m006:25Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T411:10Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Brussels Airlines goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 25/12/2025 06:25:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 25/12/2025 11:10:00. 50 Economy ticket for £111 per person are available. Travel duration is 4h 45m
-
Air France5h 5m006:00Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T411:05Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Air France goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 25/12/2025 06:00:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 25/12/2025 11:05:00. 50 Economy ticket for £92 per person are available. Travel duration is 5h 5m
-
TAP Portugal5h 25m007:40Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T413:05Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from TAP Portugal goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 25/12/2025 07:40:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 25/12/2025 13:05:00. 50 Economy ticket for £71 per person are available. Travel duration is 5h 25m
-
FlixBus16h 40m020:50MadridSur Bus Station13:30LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 25/12/2025 20:50:00 to Perrache Bus Stop, Lyon (France) arriving at 26/12/2025 13:30:00. 50 Economy ticket for £54 per person are available. Travel duration is 16h 40m
-
BlaBlaCar Bus16h 45m020:30MadridSur Bus Station13:15LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 25/12/2025 20:30:00 to Perrache Train Station, Lyon (France) arriving at 26/12/2025 13:15:00. 50 Economy ticket for £53 per person are available. Travel duration is 16h 45m
-
BlaBlaCar Bus19h 40m022:30MadridSur Bus Station18:10LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 25/12/2025 22:30:00 to Perrache Train Station, Lyon (France) arriving at 26/12/2025 18:10:00. 50 Economy ticket for £88 per person are available. Travel duration is 19h 40m
-
FlixBus19h 50m015:45MadridSur Bus Station11:35LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 25/12/2025 15:45:00 to Perrache Bus Stop, Lyon (France) arriving at 26/12/2025 11:35:00. 50 Economy ticket for £54 per person are available. Travel duration is 19h 50m
Fastest Flights Thursday
Fastest Buses Thursday
-
BlaBlaCar Bus16h 45m020:30MadridSur Bus Station13:15LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 26/12/2025 20:30:00 to Perrache Train Station, Lyon (France) arriving at 27/12/2025 13:15:00. 50 Economy ticket for £70 per person are available. Travel duration is 16h 45m
-
ALSA17h 0m011:55Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T404:55LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 26/12/2025 11:55:00 to Perrache Bus Stop, Lyon (France) arriving at 27/12/2025 04:55:00. 50 Economy ticket for £58 per person are available. Travel duration is 17h 0m
-
ALSA17h 20m011:55Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T405:15LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 26/12/2025 11:55:00 to Perrache Bus Stop, Lyon (France) arriving at 27/12/2025 05:15:00. 50 Economy ticket for £58 per person are available. Travel duration is 17h 20m
-
BlaBlaCar Bus17h 25m008:35MadridSur Bus Station02:00LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 26/12/2025 08:35:00 to Perrache Train Station, Lyon (France) arriving at 27/12/2025 02:00:00. 50 Economy ticket for £57 per person are available. Travel duration is 17h 25m
Fastest Buses Friday
Here you will find all operators and timetables for a
Bus from Madrid to Lyon
What are the most popular stations in Madrid and Lyon?
In Madrid, you will usually depart from Atocha Train Station, Chamartin Train Station or Sur Bus Station, while in Lyon you will be arriving at Perrache Bus Stop, Part-Dieu Train Station or Perrache Train Station, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Lyon from Madrid? With 6 connections between 7 Bus, Train and Flight operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Madrid and Lyon, you can pay as low as £41 with a Bus from BlaBlaCar Bus.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Air Nostrum: you will get to Lyon in just 1h 50m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Madrid and Lyon are ALSA, BlaBlaCar Bus and FlixBus, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Madrid and Lyon is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Delicias or to Caluire-et-Cuire, and look at flights from Adolfo Suárez Madrid-Barajas Airport, and landing at Lyons St. Exupery Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Madrid to Lyon?
The most popular companies between Madrid and Lyon, are ALSA, BlaBlaCar Bus and FlixBus. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: ALSA, BlaBlaCar Bus, FlixBus and 1 more.
Train companies: Iryo
Airlines: Air Europa, Air Nostrum, TAP Portugal and 2 more.
All you need to know when you travel from Madrid to Lyon
Check all information on comfort and services on all modes of transports from Madrid to Lyon. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Madrid to Lyon
How can I reach Lyon from Madrid?
Every day, there are on average 6 connections between Bus, Train and Flight, with which you can get to Lyon from Madrid.
How far is Lyon from Madrid?
The distance between Madrid and Lyon is 912.1 km.
What is the most ecofriendly mode of transport between Madrid and Lyon?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 25 kgs of CO2, a train 32 kgs, a car 155 kgs, and a flight 224 kgs.
What is the cheapest mode of transport from Madrid to Lyon?
You can get to Lyon with just £41 by taking a Bus from BlaBlaCar Bus.
What is the fastest way to get from Madrid to Lyon?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Lyon in just 1h 50m with a Flight from Air Nostrum.
More routes to Madrid and to Lyon
Looking for more options? Here you can see the most popular routes to Madrid and to Lyon. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Madrid
- A Coruña to Madrid
- Algeciras to Madrid
- Alicante to Madrid
- Ávila to Madrid
- Barcelona to Madrid
- Benidorm to Madrid
- Bilbao to Madrid
- Castellón de la Plana to Madrid
- Gandía to Madrid
- Guadalajara to Madrid
- León to Madrid
- Lisbon to Madrid
- Logroño to Madrid
- Malaga to Madrid
- Molina de Aragón to Madrid
- Ourense to Madrid
- Oviedo to Madrid
- Porto to Madrid
- San Sebastian to Madrid
- Santiago de Compostela to Madrid
- Segovia to Madrid
- Toulouse to Madrid
- Valencia to Madrid
- Vigo to Madrid
- Trips to Lyon
- Barcelona to Lyon
- Bologna to Lyon
- Bordeaux to Lyon
- Chamonix to Lyon
- Clermont-Ferrand to Lyon
- Colmar to Lyon
- Freiburg to Lyon
- Geneva Airport to Lyon
- Girona to Lyon
- Liege to Lyon
- Marseille to Lyon
- Milan to Lyon
- Montpellier to Lyon
- Moulins to Lyon
- Mulhouse to Lyon
- Nantes to Lyon
- Naples to Lyon
- Paris to Lyon
- Poitiers to Lyon
- Prague to Lyon
- Strasbourg to Lyon
- Toulon to Lyon
- Tours to Lyon
- Zurich to Lyon
