What is the best way to travel from Madrid to Lyon?
Looking for a trip? Check and compare all the available Trains, Flights and Buses to Lyon from Madrid. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 7 available companies to find your perfect trip!
What is the cheapest way to reach Lyon from Madrid?
You can reach Lyon with just £28 by taking a Bus from ALSA, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
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ALSA17h 50m010:15Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T404:05LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 21/03/2026 10:15:00 to Perrache Bus Stop, Lyon (France) arriving at 22/03/2026 04:05:00. 50 Economy ticket for £34 per person are available. Travel duration is 17h 50m
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ALSA16h 10m011:55Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T404:05LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 21/03/2026 11:55:00 to Perrache Bus Stop, Lyon (France) arriving at 22/03/2026 04:05:00. 50 Economy ticket for £34 per person are available. Travel duration is 16h 10m
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FlixBus18h 15m023:25MadridSur Bus Station17:40LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 21/03/2026 23:25:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 22/03/2026 17:40:00. 50 Economy ticket for £45 per person are available. Travel duration is 18h 15m
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BlaBlaCar Bus18h 40m006:30MadridSur Bus Station01:10LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 21/03/2026 06:30:00 to Perrache Train Station, Lyon (France) arriving at 22/03/2026 01:10:00. 50 Economy ticket for £52 per person are available. Travel duration is 18h 40m
Cheapest Buses Saturday
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ALSA18h 16m023:59MadridAvenida de América Coach Station18:15LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Avenida de América Coach Station, Madrid (Spain) at 22/03/2026 23:59:00 to Perrache Bus Stop, Lyon (France) arriving at 23/03/2026 18:15:00. 50 Economy ticket for £35 per person are available. Travel duration is 18h 16m
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ALSA17h 20m011:55Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T405:15LyonLyon Avenue Tony Garnier Coach Stop0BasicA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 22/03/2026 11:55:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 23/03/2026 05:15:00. 50 Basic ticket for £37 per person are available. Travel duration is 17h 20m
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FlixBus18h 15m023:25MadridSur Bus Station17:40LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 22/03/2026 23:25:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 23/03/2026 17:40:00. 50 Economy ticket for £46 per person are available. Travel duration is 18h 15m
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Union Ivkoni22h 30m010:00MadridMendez Alvaro Train Station08:30LyonLyon Avenue Tony Garnier Coach Stop0BasicA Bus from Union Ivkoni goes from Mendez Alvaro Train Station, Madrid (Spain) at 22/03/2026 10:00:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 23/03/2026 08:30:00. 50 Basic ticket for £54 per person are available. Travel duration is 22h 30m
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Iberia Express4h 50m007:20Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T412:10Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Iberia Express goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 22/03/2026 07:20:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 22/03/2026 12:10:00. 50 Economy ticket for £121 per person are available. Travel duration is 4h 50m
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Aeronova17h 20m006:35Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T423:55Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Aeronova goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 22/03/2026 06:35:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 22/03/2026 23:55:00. 50 Economy ticket for £132 per person are available. Travel duration is 17h 20m
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Volotea26h 45m020:40Adolfo Suárez Madrid-Barajas AirportMadrid Airport23:25Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Volotea goes from Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) at 22/03/2026 20:40:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 23/03/2026 23:25:00. 50 Economy ticket for £133 per person are available. Travel duration is 26h 45m
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Air Europa17h 20m006:35Adolfo Suárez Madrid-Barajas AirportMadrid Airport23:55Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Air Europa goes from Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) at 22/03/2026 06:35:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 22/03/2026 23:55:00. 50 Economy ticket for £145 per person are available. Travel duration is 17h 20m
Cheapest Buses Sunday
Cheapest Flights Sunday
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ALSA18h 1m000:14Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T418:15LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 23/03/2026 00:14:00 to Perrache Bus Stop, Lyon (France) arriving at 23/03/2026 18:15:00. 50 Economy ticket for £35 per person are available. Travel duration is 18h 1m
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ALSA16h 45m020:30MadridMendez Alvaro Train Station13:15LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Mendez Alvaro Train Station, Madrid (Spain) at 23/03/2026 20:30:00 to Perrache Bus Stop, Lyon (France) arriving at 24/03/2026 13:15:00. 50 Economy ticket for £37 per person are available. Travel duration is 16h 45m
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ALSA17h 20m011:55Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T405:15LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 23/03/2026 11:55:00 to Perrache Bus Stop, Lyon (France) arriving at 24/03/2026 05:15:00. 50 Economy ticket for £38 per person are available. Travel duration is 17h 20m
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FlixBus18h 15m023:25MadridSur Bus Station17:40LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 23/03/2026 23:25:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 24/03/2026 17:40:00. 50 Economy ticket for £41 per person are available. Travel duration is 18h 15m
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Ryanair10h 40m022:40Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T409:20Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Ryanair goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 23/03/2026 22:40:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 24/03/2026 09:20:00. 50 Economy ticket for £57 per person are available. Travel duration is 10h 40m
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Air Europa19h 15m012:20Adolfo Suárez Madrid-Barajas AirportMadrid Airport07:35Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Air Europa goes from Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) at 23/03/2026 12:20:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 24/03/2026 07:35:00. 50 Economy ticket for £84 per person are available. Travel duration is 19h 15m
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Volotea11h 0m012:25Adolfo Suárez Madrid-Barajas AirportMadrid Airport23:25Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Volotea goes from Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) at 23/03/2026 12:25:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 23/03/2026 23:25:00. 50 Economy ticket for £87 per person are available. Travel duration is 11h 0m
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EasyJet Airline1h 50m013:05Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T414:55Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from EasyJet Airline goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 23/03/2026 13:05:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 23/03/2026 14:55:00. 50 Economy ticket for £96 per person are available. Travel duration is 1h 50m
Cheapest Buses Monday
Cheapest Flights Monday
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ALSA18h 45m023:30Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T418:15LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 24/03/2026 23:30:00 to Perrache Bus Stop, Lyon (France) arriving at 25/03/2026 18:15:00. 50 Economy ticket for £34 per person are available. Travel duration is 18h 45m
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ALSA19h 15m023:00MadridMendez Alvaro Train Station18:15LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Mendez Alvaro Train Station, Madrid (Spain) at 24/03/2026 23:00:00 to Perrache Bus Stop, Lyon (France) arriving at 25/03/2026 18:15:00. 50 Economy ticket for £34 per person are available. Travel duration is 19h 15m
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FlixBus18h 15m023:25MadridSur Bus Station17:40LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 24/03/2026 23:25:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 25/03/2026 17:40:00. 50 Economy ticket for £40 per person are available. Travel duration is 18h 15m
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Union Ivkoni22h 0m010:00MadridMendez Alvaro Train Station08:00LyonLyon Avenue Tony Garnier Coach Stop0BasicA Bus from Union Ivkoni goes from Mendez Alvaro Train Station, Madrid (Spain) at 24/03/2026 10:00:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 25/03/2026 08:00:00. 50 Basic ticket for £41 per person are available. Travel duration is 22h 0m
Cheapest Buses Tuesday
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ALSA16h 45m009:15Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T402:00LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 25/03/2026 09:15:00 to Perrache Bus Stop, Lyon (France) arriving at 26/03/2026 02:00:00. 50 Economy ticket for £34 per person are available. Travel duration is 16h 45m
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ALSA17h 25m008:35MadridMendez Alvaro Train Station02:00LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Mendez Alvaro Train Station, Madrid (Spain) at 25/03/2026 08:35:00 to Perrache Bus Stop, Lyon (France) arriving at 26/03/2026 02:00:00. 50 Economy ticket for £34 per person are available. Travel duration is 17h 25m
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FlixBus18h 15m023:25MadridSur Bus Station17:40LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 25/03/2026 23:25:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 26/03/2026 17:40:00. 50 Economy ticket for £40 per person are available. Travel duration is 18h 15m
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BlaBlaCar Bus21h 0m023:00MadridSur Bus Station20:00LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 25/03/2026 23:00:00 to Perrache Train Station, Lyon (France) arriving at 26/03/2026 20:00:00. 50 Economy ticket for £44 per person are available. Travel duration is 21h 0m
Cheapest Buses Wednesday
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ALSA17h 20m011:55Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T405:15LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 26/03/2026 11:55:00 to Perrache Bus Stop, Lyon (France) arriving at 27/03/2026 05:15:00. 50 Economy ticket for £34 per person are available. Travel duration is 17h 20m
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ALSA16h 0m013:15Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T405:15LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 26/03/2026 13:15:00 to Perrache Bus Stop, Lyon (France) arriving at 27/03/2026 05:15:00. 50 Economy ticket for £34 per person are available. Travel duration is 16h 0m
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FlixBus18h 15m023:25MadridSur Bus Station17:40LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 26/03/2026 23:25:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 27/03/2026 17:40:00. 50 Economy ticket for £77 per person are available. Travel duration is 18h 15m
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FlixBus18h 55m015:55MadridSur Bus Station10:50LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 26/03/2026 15:55:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 27/03/2026 10:50:00. 50 Economy ticket for £81 per person are available. Travel duration is 18h 55m
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Air Europa14h 25m006:35Adolfo Suárez Madrid-Barajas AirportMadrid Airport21:00Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Air Europa goes from Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) at 26/03/2026 06:35:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 26/03/2026 21:00:00. 50 Economy ticket for £78 per person are available. Travel duration is 14h 25m
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Vueling Airlines13h 25m019:40Adolfo Suárez Madrid-Barajas AirportMadrid Airport09:05Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Vueling Airlines goes from Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) at 26/03/2026 19:40:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 27/03/2026 09:05:00. 50 Economy ticket for £106 per person are available. Travel duration is 13h 25m
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Volotea1h 45m020:55Adolfo Suárez Madrid-Barajas AirportMadrid Airport22:40Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Volotea goes from Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) at 26/03/2026 20:55:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 26/03/2026 22:40:00. 50 Economy ticket for £110 per person are available. Travel duration is 1h 45m
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Iberia15h 45m023:45Adolfo Suárez Madrid-Barajas AirportMadrid Airport15:30Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Iberia goes from Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) at 26/03/2026 23:45:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 27/03/2026 15:30:00. 50 Economy ticket for £123 per person are available. Travel duration is 15h 45m
Cheapest Buses Thursday
Cheapest Flights Thursday
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ALSA17h 25m008:35MadridMendez Alvaro Train Station02:00LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Mendez Alvaro Train Station, Madrid (Spain) at 27/03/2026 08:35:00 to Perrache Bus Stop, Lyon (France) arriving at 28/03/2026 02:00:00. 50 Economy ticket for £28 per person are available. Travel duration is 17h 25m
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Union Ivkoni23h 0m010:00MadridSur Bus Station09:00LyonLyon Avenue Tony Garnier Coach Stop0BasicA Bus from Union Ivkoni goes from Sur Bus Station, Madrid (Spain) at 27/03/2026 10:00:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 28/03/2026 09:00:00. 50 Basic ticket for £34 per person are available. Travel duration is 23h 0m
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BlaBlaCar Bus18h 40m006:30MadridSur Bus Station01:10LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 27/03/2026 06:30:00 to Perrache Train Station, Lyon (France) arriving at 28/03/2026 01:10:00. 50 Economy ticket for £52 per person are available. Travel duration is 18h 40m
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FlixBus18h 15m023:25MadridSur Bus Station17:40LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 27/03/2026 23:25:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 28/03/2026 17:40:00. 50 Economy ticket for £89 per person are available. Travel duration is 18h 15m
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EasyJet Airline1h 50m017:40Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T419:30Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from EasyJet Airline goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 27/03/2026 17:40:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 27/03/2026 19:30:00. 50 Economy ticket for £92 per person are available. Travel duration is 1h 50m
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Skyscanner1h 50m017:40Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T419:30Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Skyscanner goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 27/03/2026 17:40:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 27/03/2026 19:30:00. 50 Economy ticket for £100 per person are available. Travel duration is 1h 50m
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Vueling Airlines10h 5m021:30Adolfo Suárez Madrid-Barajas AirportMadrid Airport07:35Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Vueling Airlines goes from Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) at 27/03/2026 21:30:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 28/03/2026 07:35:00. 50 Economy ticket for £110 per person are available. Travel duration is 10h 5m
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Volotea1h 45m020:55Adolfo Suárez Madrid-Barajas AirportMadrid Airport22:40Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Volotea goes from Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) at 27/03/2026 20:55:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 27/03/2026 22:40:00. 50 Economy ticket for £110 per person are available. Travel duration is 1h 45m
Cheapest Buses Friday
Cheapest Flights Friday
What are the fastest trips from Madrid to Lyon?
You can get to Lyon from Madrid in just 1h 45m with a Flight from Volotea. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
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ALSA16h 10m011:55Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T404:05LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 21/03/2026 11:55:00 to Perrache Bus Stop, Lyon (France) arriving at 22/03/2026 04:05:00. 50 Economy ticket for £34 per person are available. Travel duration is 16h 10m
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ALSA17h 50m010:15Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T404:05LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 21/03/2026 10:15:00 to Perrache Bus Stop, Lyon (France) arriving at 22/03/2026 04:05:00. 50 Economy ticket for £34 per person are available. Travel duration is 17h 50m
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FlixBus18h 15m023:25MadridSur Bus Station17:40LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 21/03/2026 23:25:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 22/03/2026 17:40:00. 50 Economy ticket for £45 per person are available. Travel duration is 18h 15m
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BlaBlaCar Bus18h 40m006:30MadridSur Bus Station01:10LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 21/03/2026 06:30:00 to Perrache Train Station, Lyon (France) arriving at 22/03/2026 01:10:00. 50 Economy ticket for £52 per person are available. Travel duration is 18h 40m
Fastest Buses Saturday
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Iberia Express4h 50m007:20Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T412:10Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Iberia Express goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 22/03/2026 07:20:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 22/03/2026 12:10:00. 50 Economy ticket for £121 per person are available. Travel duration is 4h 50m
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Aeronova17h 20m006:35Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T423:55Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Aeronova goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 22/03/2026 06:35:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 22/03/2026 23:55:00. 50 Economy ticket for £132 per person are available. Travel duration is 17h 20m
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Air Europa17h 20m006:35Adolfo Suárez Madrid-Barajas AirportMadrid Airport23:55Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Air Europa goes from Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) at 22/03/2026 06:35:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 22/03/2026 23:55:00. 50 Economy ticket for £145 per person are available. Travel duration is 17h 20m
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TAP Portugal22h 0m012:10Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T410:10Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from TAP Portugal goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 22/03/2026 12:10:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 23/03/2026 10:10:00. 50 Economy ticket for £163 per person are available. Travel duration is 22h 0m
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ALSA17h 20m011:55Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T405:15LyonLyon Avenue Tony Garnier Coach Stop0BasicA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 22/03/2026 11:55:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 23/03/2026 05:15:00. 50 Basic ticket for £37 per person are available. Travel duration is 17h 20m
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BlaBlaCar Bus17h 20m008:35MadridSur Bus Station01:55LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 22/03/2026 08:35:00 to Perrache Train Station, Lyon (France) arriving at 23/03/2026 01:55:00. 50 Economy ticket for £56 per person are available. Travel duration is 17h 20m
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FlixBus18h 15m023:25MadridSur Bus Station17:40LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 22/03/2026 23:25:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 23/03/2026 17:40:00. 50 Economy ticket for £46 per person are available. Travel duration is 18h 15m
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ALSA18h 16m023:59MadridAvenida de América Coach Station18:15LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Avenida de América Coach Station, Madrid (Spain) at 22/03/2026 23:59:00 to Perrache Bus Stop, Lyon (France) arriving at 23/03/2026 18:15:00. 50 Economy ticket for £35 per person are available. Travel duration is 18h 16m
Fastest Flights Sunday
Fastest Buses Sunday
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EasyJet Airline1h 50m013:05Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T414:55Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from EasyJet Airline goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 23/03/2026 13:05:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 23/03/2026 14:55:00. 50 Economy ticket for £96 per person are available. Travel duration is 1h 50m
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Iberia10h 0m021:35Adolfo Suárez Madrid-Barajas AirportMadrid Airport07:35Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Iberia goes from Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) at 23/03/2026 21:35:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 24/03/2026 07:35:00. 50 Economy ticket for £107 per person are available. Travel duration is 10h 0m
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Ryanair10h 40m022:40Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T409:20Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Ryanair goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 23/03/2026 22:40:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 24/03/2026 09:20:00. 50 Economy ticket for £57 per person are available. Travel duration is 10h 40m
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Volotea11h 0m012:25Adolfo Suárez Madrid-Barajas AirportMadrid Airport23:25Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Volotea goes from Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) at 23/03/2026 12:25:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 23/03/2026 23:25:00. 50 Economy ticket for £87 per person are available. Travel duration is 11h 0m
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FlixBus16h 40m020:50MadridSur Bus Station13:30LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 23/03/2026 20:50:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 24/03/2026 13:30:00. 50 Economy ticket for £60 per person are available. Travel duration is 16h 40m
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ALSA16h 45m020:30MadridMendez Alvaro Train Station13:15LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Mendez Alvaro Train Station, Madrid (Spain) at 23/03/2026 20:30:00 to Perrache Bus Stop, Lyon (France) arriving at 24/03/2026 13:15:00. 50 Economy ticket for £37 per person are available. Travel duration is 16h 45m
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ALSA17h 20m011:55Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T405:15LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 23/03/2026 11:55:00 to Perrache Bus Stop, Lyon (France) arriving at 24/03/2026 05:15:00. 50 Economy ticket for £38 per person are available. Travel duration is 17h 20m
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ALSA18h 1m000:14Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T418:15LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 23/03/2026 00:14:00 to Perrache Bus Stop, Lyon (France) arriving at 23/03/2026 18:15:00. 50 Economy ticket for £35 per person are available. Travel duration is 18h 1m
Fastest Flights Monday
Fastest Buses Monday
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FlixBus18h 15m023:25MadridSur Bus Station17:40LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 24/03/2026 23:25:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 25/03/2026 17:40:00. 50 Economy ticket for £40 per person are available. Travel duration is 18h 15m
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ALSA18h 45m023:30Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T418:15LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 24/03/2026 23:30:00 to Perrache Bus Stop, Lyon (France) arriving at 25/03/2026 18:15:00. 50 Economy ticket for £34 per person are available. Travel duration is 18h 45m
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ALSA19h 15m023:00MadridMendez Alvaro Train Station18:15LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Mendez Alvaro Train Station, Madrid (Spain) at 24/03/2026 23:00:00 to Perrache Bus Stop, Lyon (France) arriving at 25/03/2026 18:15:00. 50 Economy ticket for £34 per person are available. Travel duration is 19h 15m
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Union Ivkoni22h 0m010:00MadridMendez Alvaro Train Station08:00LyonLyon Avenue Tony Garnier Coach Stop0BasicA Bus from Union Ivkoni goes from Mendez Alvaro Train Station, Madrid (Spain) at 24/03/2026 10:00:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 25/03/2026 08:00:00. 50 Basic ticket for £41 per person are available. Travel duration is 22h 0m
Fastest Buses Tuesday
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ALSA16h 45m009:15Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T402:00LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 25/03/2026 09:15:00 to Perrache Bus Stop, Lyon (France) arriving at 26/03/2026 02:00:00. 50 Economy ticket for £34 per person are available. Travel duration is 16h 45m
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BlaBlaCar Bus17h 20m008:35MadridSur Bus Station01:55LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 25/03/2026 08:35:00 to Perrache Train Station, Lyon (France) arriving at 26/03/2026 01:55:00. 50 Economy ticket for £47 per person are available. Travel duration is 17h 20m
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ALSA17h 25m008:35MadridMendez Alvaro Train Station02:00LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Mendez Alvaro Train Station, Madrid (Spain) at 25/03/2026 08:35:00 to Perrache Bus Stop, Lyon (France) arriving at 26/03/2026 02:00:00. 50 Economy ticket for £34 per person are available. Travel duration is 17h 25m
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FlixBus18h 15m023:25MadridSur Bus Station17:40LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 25/03/2026 23:25:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 26/03/2026 17:40:00. 50 Economy ticket for £40 per person are available. Travel duration is 18h 15m
Fastest Buses Wednesday
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Volotea1h 45m020:55Adolfo Suárez Madrid-Barajas AirportMadrid Airport22:40Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Volotea goes from Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) at 26/03/2026 20:55:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 26/03/2026 22:40:00. 50 Economy ticket for £110 per person are available. Travel duration is 1h 45m
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Brussels Airlines9h 55m012:35Adolfo Suárez Madrid-Barajas AirportMadrid Airport22:30Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Brussels Airlines goes from Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) at 26/03/2026 12:35:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 26/03/2026 22:30:00. 50 Economy ticket for £155 per person are available. Travel duration is 9h 55m
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Vueling Airlines13h 25m019:40Adolfo Suárez Madrid-Barajas AirportMadrid Airport09:05Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Vueling Airlines goes from Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) at 26/03/2026 19:40:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 27/03/2026 09:05:00. 50 Economy ticket for £106 per person are available. Travel duration is 13h 25m
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Air Europa14h 25m006:35Adolfo Suárez Madrid-Barajas AirportMadrid Airport21:00Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Air Europa goes from Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) at 26/03/2026 06:35:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 26/03/2026 21:00:00. 50 Economy ticket for £78 per person are available. Travel duration is 14h 25m
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ALSA16h 0m013:15Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T405:15LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 26/03/2026 13:15:00 to Perrache Bus Stop, Lyon (France) arriving at 27/03/2026 05:15:00. 50 Economy ticket for £34 per person are available. Travel duration is 16h 0m
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BlaBlaCar Bus16h 45m020:30MadridSur Bus Station13:15LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 26/03/2026 20:30:00 to Perrache Train Station, Lyon (France) arriving at 27/03/2026 13:15:00. 50 Economy ticket for £95 per person are available. Travel duration is 16h 45m
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ALSA17h 20m011:55Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T405:15LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 26/03/2026 11:55:00 to Perrache Bus Stop, Lyon (France) arriving at 27/03/2026 05:15:00. 50 Economy ticket for £34 per person are available. Travel duration is 17h 20m
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FlixBus18h 15m023:25MadridSur Bus Station17:40LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 26/03/2026 23:25:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 27/03/2026 17:40:00. 50 Economy ticket for £77 per person are available. Travel duration is 18h 15m
Fastest Flights Thursday
Fastest Buses Thursday
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Volotea1h 45m020:55Adolfo Suárez Madrid-Barajas AirportMadrid Airport22:40Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Volotea goes from Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) at 27/03/2026 20:55:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 27/03/2026 22:40:00. 50 Economy ticket for £110 per person are available. Travel duration is 1h 45m
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EasyJet Airline1h 50m017:40Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T419:30Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from EasyJet Airline goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 27/03/2026 17:40:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 27/03/2026 19:30:00. 50 Economy ticket for £92 per person are available. Travel duration is 1h 50m
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Skyscanner1h 50m017:40Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T419:30Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Skyscanner goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 27/03/2026 17:40:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 27/03/2026 19:30:00. 50 Economy ticket for £100 per person are available. Travel duration is 1h 50m
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Aeronova8h 0m006:35Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T414:35Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Aeronova goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 27/03/2026 06:35:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 27/03/2026 14:35:00. 50 Economy ticket for £138 per person are available. Travel duration is 8h 0m
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ALSA17h 25m008:35MadridMendez Alvaro Train Station02:00LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Mendez Alvaro Train Station, Madrid (Spain) at 27/03/2026 08:35:00 to Perrache Bus Stop, Lyon (France) arriving at 28/03/2026 02:00:00. 50 Economy ticket for £28 per person are available. Travel duration is 17h 25m
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Internorte Transportes17h 25m008:35Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T402:00LyonPart-Dieu Train Station0BasicA Bus from Internorte Transportes goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 27/03/2026 08:35:00 to Part-Dieu Train Station, Lyon (France) arriving at 28/03/2026 02:00:00. 50 Basic ticket for £107 per person are available. Travel duration is 17h 25m
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FlixBus18h 15m023:25MadridSur Bus Station17:40LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 27/03/2026 23:25:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 28/03/2026 17:40:00. 50 Economy ticket for £89 per person are available. Travel duration is 18h 15m
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BlaBlaCar Bus18h 40m006:30MadridSur Bus Station01:10LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 27/03/2026 06:30:00 to Perrache Train Station, Lyon (France) arriving at 28/03/2026 01:10:00. 50 Economy ticket for £52 per person are available. Travel duration is 18h 40m
Fastest Flights Friday
Fastest Buses Friday
Here you will find all operators and timetables for a
Bus from Madrid to Lyon
What are the most popular stations in Madrid and Lyon?
In Madrid, you will usually depart from Chamartin Train Station, Sur Bus Station or Atocha Train Station, while in Lyon you will be arriving at Perrache Bus Stop, Part-Dieu Train Station or Perrache Train Station, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Lyon from Madrid? With 7 connections between 7 Flight, Train and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Madrid and Lyon, you can pay as low as £28 with a Bus from ALSA.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Volotea: you will get to Lyon in just 1h 45m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Madrid and Lyon are ALSA, FlixBus and BlaBlaCar Bus, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Madrid and Lyon is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Delicias or to Caluire-et-Cuire, and look at flights from Adolfo Suárez Madrid-Barajas Airport, and landing at Lyons St. Exupery Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Madrid to Lyon?
The most popular companies between Madrid and Lyon, are ALSA, FlixBus and BlaBlaCar Bus. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: ALSA, FlixBus, BlaBlaCar Bus and 2 more.
Airlines: Volotea, Air Europa, Aeronova and 8 more.
All you need to know when you travel from Madrid to Lyon
Check all information on comfort and services on all modes of transports from Madrid to Lyon. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Madrid to Lyon
How can I reach Lyon from Madrid?
Every day, there are on average 7 connections between Flight, Train and Bus, with which you can get to Lyon from Madrid.
How far is Lyon from Madrid?
The distance between Madrid and Lyon is 912.1 km.
What is the most ecofriendly mode of transport between Madrid and Lyon?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 25 kgs of CO2, a train 32 kgs, a car 155 kgs, and a flight 224 kgs.
What is the cheapest mode of transport from Madrid to Lyon?
You can get to Lyon with just £28 by taking a Bus from ALSA.
What is the fastest way to get from Madrid to Lyon?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Lyon in just 1h 45m with a Flight from Volotea.
More routes to Madrid and to Lyon
Looking for more options? Here you can see the most popular routes to Madrid and to Lyon. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Madrid
- A Coruña to Madrid
- Algeciras to Madrid
- Alicante to Madrid
- Ávila to Madrid
- Barcelona to Madrid
- Benidorm to Madrid
- Castellón de la Plana to Madrid
- Cordoba to Madrid
- Huelva to Madrid
- Lisbon to Madrid
- Logroño to Madrid
- Malaga to Madrid
- Marbella to Madrid
- Mérida to Madrid
- Ourense to Madrid
- Oviedo to Madrid
- Porto to Madrid
- San Sebastian to Madrid
- Santiago de Compostela to Madrid
- Segovia to Madrid
- Seville to Madrid
- Toulouse to Madrid
- Valencia to Madrid
- Vigo to Madrid
- Trips to Lyon
- Alicante to Lyon
- Annecy to Lyon
- Barcelona to Lyon
- Basel to Lyon
- Bologna to Lyon
- Bordeaux to Lyon
- Chambery to Lyon
- Clermont-Ferrand to Lyon
- Dusseldorf to Lyon
- Geneva to Lyon
- Genoa to Lyon
- Grenoble to Lyon
- Lille to Lyon
- Marseille to Lyon
- Milan to Lyon
- Nantes to Lyon
- Nimes to Lyon
- Orleans to Lyon
- Paris Charles de Gaulle Airport to Lyon
- Paris to Lyon
- Saint-Étienne to Lyon
- Toulouse to Lyon
- Turin to Lyon
- Valencia to Lyon
