What is the best way to travel from Prague to Brussels?
Looking for a trip? Check and compare all the available Flights and Buses to Brussels from Prague. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 2 available companies to find your perfect trip!
What is the cheapest way to reach Brussels from Prague?
You can reach Brussels with just £34 by taking a Flight from Buzz, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
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FlixBus13h 20m011:05PragueÚAN Florenc00:25BrusselsNorth Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 02/02/2026 11:05:00 to North Station, Brussels (Belgium) arriving at 03/02/2026 00:25:00. 50 Economy ticket for £44 per person are available. Travel duration is 13h 20m
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FlixBus19h 30m022:45Prague AirportPrague Airport - T1/218:15BrusselsNorth Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 02/02/2026 22:45:00 to North Station, Brussels (Belgium) arriving at 03/02/2026 18:15:00. 50 Economy ticket for £45 per person are available. Travel duration is 19h 30m
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FlixBus15h 5m016:15PragueÚAN Florenc07:20BrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 02/02/2026 16:15:00 to Midi Bus Station, Brussels (Belgium) arriving at 03/02/2026 07:20:00. 50 Economy ticket for £47 per person are available. Travel duration is 15h 5m
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FlixBus15h 35m008:50Prague AirportPrague Airport - T1/200:25BrusselsNorth Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 02/02/2026 08:50:00 to North Station, Brussels (Belgium) arriving at 03/02/2026 00:25:00. 50 Economy ticket for £48 per person are available. Travel duration is 15h 35m
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FlixBus20h 0m011:20Prague AirportPrague Airport - T1/207:20BrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 02/02/2026 11:20:00 to Midi Bus Station, Brussels (Belgium) arriving at 03/02/2026 07:20:00. 50 Economy ticket for £49 per person are available. Travel duration is 20h 0m
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Smartwings7h 45m006:00Prague AirportPrague Airport - T1/213:45Antwerp AirportAntwerp Airport0EconomyA Flight from Smartwings goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 02/02/2026 06:00:00 to Antwerp Airport, Antwerp Airport (Belgium) arriving at 02/02/2026 13:45:00. 50 Economy ticket for £114 per person are available. Travel duration is 7h 45m
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Ryanair23h 10m013:55Prague AirportPrague Airport - T1/213:05Antwerp AirportAntwerp Airport0EconomyA Flight from Ryanair goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 02/02/2026 13:55:00 to Antwerp Airport, Antwerp Airport (Belgium) arriving at 03/02/2026 13:05:00. 50 Economy ticket for £131 per person are available. Travel duration is 23h 10m
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Buzz26h 20m010:45Prague AirportPrague Airport - T1/213:05Antwerp AirportAntwerp Airport0EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 02/02/2026 10:45:00 to Antwerp Airport, Antwerp Airport (Belgium) arriving at 03/02/2026 13:05:00. 50 Economy ticket for £148 per person are available. Travel duration is 26h 20m
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Skyscanner27h 25m009:40Prague AirportPrague Airport - T1/213:05Antwerp AirportAntwerp Airport0EconomyA Flight from Skyscanner goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 02/02/2026 09:40:00 to Antwerp Airport, Antwerp Airport (Belgium) arriving at 03/02/2026 13:05:00. 50 Economy ticket for £155 per person are available. Travel duration is 27h 25m
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EasyJet Airline26h 10m010:55Prague AirportPrague Airport - T1/213:05Antwerp AirportAntwerp Airport0EconomyA Flight from EasyJet Airline goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 02/02/2026 10:55:00 to Antwerp Airport, Antwerp Airport (Belgium) arriving at 03/02/2026 13:05:00. 50 Economy ticket for £155 per person are available. Travel duration is 26h 10m
Cheapest Buses Monday
Cheapest Flights Monday
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FlixBus13h 20m011:05PragueÚAN Florenc00:25BrusselsNorth Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 03/02/2026 11:05:00 to North Station, Brussels (Belgium) arriving at 04/02/2026 00:25:00. 50 Economy ticket for £42 per person are available. Travel duration is 13h 20m
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FlixBus15h 35m008:50Prague AirportPrague Airport - T1/200:25BrusselsNorth Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 03/02/2026 08:50:00 to North Station, Brussels (Belgium) arriving at 04/02/2026 00:25:00. 50 Economy ticket for £44 per person are available. Travel duration is 15h 35m
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FlixBus15h 5m016:15PragueÚAN Florenc07:20BrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 03/02/2026 16:15:00 to Midi Bus Station, Brussels (Belgium) arriving at 04/02/2026 07:20:00. 50 Economy ticket for £46 per person are available. Travel duration is 15h 5m
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European Sleeper16h 28m018:00PragueWilsonova Coach Station10:28BrusselsMidi Bus Station0EconomyA Bus from European Sleeper goes from Wilsonova Coach Station, Prague (Czech Republic) at 03/02/2026 18:00:00 to Midi Bus Station, Brussels (Belgium) arriving at 04/02/2026 10:28:00. 50 Economy ticket for £208 per person are available. Travel duration is 16h 28m
Cheapest Buses Tuesday
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FlixBus13h 20m011:05PragueÚAN Florenc00:25BrusselsNorth Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 04/02/2026 11:05:00 to North Station, Brussels (Belgium) arriving at 05/02/2026 00:25:00. 50 Economy ticket for £36 per person are available. Travel duration is 13h 20m
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FlixBus15h 5m016:15PragueÚAN Florenc07:20BrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 04/02/2026 16:15:00 to Midi Bus Station, Brussels (Belgium) arriving at 05/02/2026 07:20:00. 50 Economy ticket for £38 per person are available. Travel duration is 15h 5m
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FlixBus15h 35m008:50Prague AirportPrague Airport - T1/200:25BrusselsNorth Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 04/02/2026 08:50:00 to North Station, Brussels (Belgium) arriving at 05/02/2026 00:25:00. 50 Economy ticket for £38 per person are available. Travel duration is 15h 35m
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FlixBus18h 45m008:50Prague AirportPrague Airport - T1/203:35BrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 04/02/2026 08:50:00 to Midi Bus Station, Brussels (Belgium) arriving at 05/02/2026 03:35:00. 50 Economy ticket for £38 per person are available. Travel duration is 18h 45m
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FlixBus17h 45m022:45Prague AirportPrague Airport - T1/216:30BrusselsNorth Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 04/02/2026 22:45:00 to North Station, Brussels (Belgium) arriving at 05/02/2026 16:30:00. 50 Economy ticket for £40 per person are available. Travel duration is 17h 45m
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Wizz Air29h 40m008:05Prague AirportPrague Airport - T1/213:45Antwerp AirportAntwerp Airport0EconomyA Flight from Wizz Air goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 04/02/2026 08:05:00 to Antwerp Airport, Antwerp Airport (Belgium) arriving at 05/02/2026 13:45:00. 50 Economy ticket for £96 per person are available. Travel duration is 29h 40m
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Ryanair27h 45m010:00Prague AirportPrague Airport - T1/213:45Antwerp AirportAntwerp Airport0EconomyA Flight from Ryanair goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 04/02/2026 10:00:00 to Antwerp Airport, Antwerp Airport (Belgium) arriving at 05/02/2026 13:45:00. 50 Economy ticket for £103 per person are available. Travel duration is 27h 45m
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Smartwings21h 15m016:30Prague AirportPrague Airport - T1/213:45Antwerp AirportAntwerp Airport0EconomyA Flight from Smartwings goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 04/02/2026 16:30:00 to Antwerp Airport, Antwerp Airport (Belgium) arriving at 05/02/2026 13:45:00. 50 Economy ticket for £103 per person are available. Travel duration is 21h 15m
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Buzz31h 45m006:00Prague AirportPrague Airport - T1/213:45Antwerp AirportAntwerp Airport0EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 04/02/2026 06:00:00 to Antwerp Airport, Antwerp Airport (Belgium) arriving at 05/02/2026 13:45:00. 50 Economy ticket for £113 per person are available. Travel duration is 31h 45m
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Air Bagan25h 25m019:15Prague AirportPrague Airport - T1/220:40Antwerp AirportAntwerp Airport0EconomyA Flight from Air Bagan goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 04/02/2026 19:15:00 to Antwerp Airport, Antwerp Airport (Belgium) arriving at 05/02/2026 20:40:00. 50 Economy ticket for £139 per person are available. Travel duration is 25h 25m
Cheapest Buses Wednesday
Cheapest Flights Wednesday
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FlixBus14h 15m003:50PragueWilsonova Coach Station18:05BrusselsNorth Station0EconomyA Bus from FlixBus goes from Wilsonova Coach Station, Prague (Czech Republic) at 05/02/2026 03:50:00 to North Station, Brussels (Belgium) arriving at 05/02/2026 18:05:00. 50 Economy ticket for £38 per person are available. Travel duration is 14h 15m
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FlixBus13h 55m004:10PragueNa Knížecí Station18:05BrusselsNorth Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 05/02/2026 04:10:00 to North Station, Brussels (Belgium) arriving at 05/02/2026 18:05:00. 50 Economy ticket for £38 per person are available. Travel duration is 13h 55m
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FlixBus13h 20m011:05PragueÚAN Florenc00:25BrusselsNorth Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 05/02/2026 11:05:00 to North Station, Brussels (Belgium) arriving at 06/02/2026 00:25:00. 50 Economy ticket for £38 per person are available. Travel duration is 13h 20m
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European Sleeper15h 27m018:00PragueWilsonova Coach Station09:27BrusselsMidi Bus Station0EconomyA Bus from European Sleeper goes from Wilsonova Coach Station, Prague (Czech Republic) at 05/02/2026 18:00:00 to Midi Bus Station, Brussels (Belgium) arriving at 06/02/2026 09:27:00. 50 Economy ticket for £213 per person are available. Travel duration is 15h 27m
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Smartwings1h 30m006:40Prague AirportPrague Airport08:10Brussels AirportBrussels Airport0EconomyA Flight from Smartwings goes from Prague Airport, Prague Airport (Czech Republic) at 05/02/2026 06:40:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 05/02/2026 08:10:00. 50 Economy ticket for £53 per person are available. Travel duration is 1h 30m
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Fly One12h 50m019:00Prague AirportPrague Airport07:50Brussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Fly One goes from Prague Airport, Prague Airport (Czech Republic) at 05/02/2026 19:00:00 to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 06/02/2026 07:50:00. 50 Economy ticket for £88 per person are available. Travel duration is 12h 50m
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EasyJet Airline11h 30m021:10Prague AirportPrague Airport08:40Brussels AirportBrussels Airport0EconomyA Flight from EasyJet Airline goes from Prague Airport, Prague Airport (Czech Republic) at 05/02/2026 21:10:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 06/02/2026 08:40:00. 50 Economy ticket for £108 per person are available. Travel duration is 11h 30m
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Smartwings7h 45m006:00Prague AirportPrague Airport - T1/213:45Antwerp AirportAntwerp Airport0EconomyA Flight from Smartwings goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 05/02/2026 06:00:00 to Antwerp Airport, Antwerp Airport (Belgium) arriving at 05/02/2026 13:45:00. 50 Economy ticket for £122 per person are available. Travel duration is 7h 45m
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Air Bagan27h 30m018:50Prague AirportPrague Airport - T1/222:20Antwerp AirportAntwerp Airport0EconomyA Flight from Air Bagan goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 05/02/2026 18:50:00 to Antwerp Airport, Antwerp Airport (Belgium) arriving at 06/02/2026 22:20:00. 50 Economy ticket for £140 per person are available. Travel duration is 27h 30m
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Ryanair36h 30m009:50Prague AirportPrague Airport - T1/222:20Antwerp AirportAntwerp Airport0EconomyA Flight from Ryanair goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 05/02/2026 09:50:00 to Antwerp Airport, Antwerp Airport (Belgium) arriving at 06/02/2026 22:20:00. 50 Economy ticket for £149 per person are available. Travel duration is 36h 30m
Cheapest Buses Thursday
Cheapest Flights Thursday
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FlixBus13h 20m011:05PragueÚAN Florenc00:25BrusselsNorth Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 06/02/2026 11:05:00 to North Station, Brussels (Belgium) arriving at 07/02/2026 00:25:00. 50 Economy ticket for £41 per person are available. Travel duration is 13h 20m
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FlixBus14h 15m003:50PragueWilsonova Coach Station18:05BrusselsNorth Station0EconomyA Bus from FlixBus goes from Wilsonova Coach Station, Prague (Czech Republic) at 06/02/2026 03:50:00 to North Station, Brussels (Belgium) arriving at 06/02/2026 18:05:00. 50 Economy ticket for £42 per person are available. Travel duration is 14h 15m
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FlixBus13h 55m004:10PragueNa Knížecí Station18:05BrusselsNorth Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 06/02/2026 04:10:00 to North Station, Brussels (Belgium) arriving at 06/02/2026 18:05:00. 50 Economy ticket for £42 per person are available. Travel duration is 13h 55m
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FlixBus15h 5m016:15PragueÚAN Florenc07:20BrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 06/02/2026 16:15:00 to Midi Bus Station, Brussels (Belgium) arriving at 07/02/2026 07:20:00. 50 Economy ticket for £44 per person are available. Travel duration is 15h 5m
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FlixBus14h 50m023:05PragueÚAN Florenc13:55BrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 06/02/2026 23:05:00 to Midi Bus Station, Brussels (Belgium) arriving at 07/02/2026 13:55:00. 50 Economy ticket for £44 per person are available. Travel duration is 14h 50m
Cheapest Buses Friday
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Buzz1h 30m014:35Prague AirportPrague Airport - T1/216:05Brussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 07/02/2026 14:35:00 to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 07/02/2026 16:05:00. 50 Economy ticket for £34 per person are available. Travel duration is 1h 30m
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Smartwings1h 30m006:40Prague AirportPrague Airport - T1/208:10Brussels AirportBrussels Airport0EconomyA Flight from Smartwings goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 07/02/2026 06:40:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 07/02/2026 08:10:00. 50 Economy ticket for £49 per person are available. Travel duration is 1h 30m
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Skyscanner6h 50m014:45Prague AirportPrague Airport - T1/221:35Brussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Skyscanner goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 07/02/2026 14:45:00 to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 07/02/2026 21:35:00. 50 Economy ticket for £52 per person are available. Travel duration is 6h 50m
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Skyscanner5h 30m009:20Prague AirportPrague Airport - T1/214:50Brussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Skyscanner goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 07/02/2026 09:20:00 to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 07/02/2026 14:50:00. 50 Economy ticket for £55 per person are available. Travel duration is 5h 30m
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Ryanair11h 5m022:00Prague AirportPrague Airport - T1/209:05Brussels AirportBrussels Airport0EconomyA Flight from Ryanair goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 07/02/2026 22:00:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 08/02/2026 09:05:00. 50 Economy ticket for £57 per person are available. Travel duration is 11h 5m
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Ryanair5h 0m015:45Prague AirportPrague Airport - T1/220:45Brussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Ryanair goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 07/02/2026 15:45:00 to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 07/02/2026 20:45:00. 50 Economy ticket for £60 per person are available. Travel duration is 5h 0m
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FlixBus13h 20m010:35PragueÚAN Florenc23:55BrusselsNorth Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 07/02/2026 10:35:00 to North Station, Brussels (Belgium) arriving at 07/02/2026 23:55:00. 50 Economy ticket for £39 per person are available. Travel duration is 13h 20m
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FlixBus14h 15m003:50PragueWilsonova Coach Station18:05BrusselsNorth Station0EconomyA Bus from FlixBus goes from Wilsonova Coach Station, Prague (Czech Republic) at 07/02/2026 03:50:00 to North Station, Brussels (Belgium) arriving at 07/02/2026 18:05:00. 50 Economy ticket for £41 per person are available. Travel duration is 14h 15m
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FlixBus13h 55m004:10PragueNa Knížecí Station18:05BrusselsNorth Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 07/02/2026 04:10:00 to North Station, Brussels (Belgium) arriving at 07/02/2026 18:05:00. 50 Economy ticket for £41 per person are available. Travel duration is 13h 55m
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FlixBus15h 5m008:50Prague AirportPrague Airport - T1/223:55BrusselsNorth Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 07/02/2026 08:50:00 to North Station, Brussels (Belgium) arriving at 07/02/2026 23:55:00. 50 Economy ticket for £43 per person are available. Travel duration is 15h 5m
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FlixBus15h 5m016:15PragueÚAN Florenc07:20BrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 07/02/2026 16:15:00 to Midi Bus Station, Brussels (Belgium) arriving at 08/02/2026 07:20:00. 50 Economy ticket for £44 per person are available. Travel duration is 15h 5m
Cheapest Flights Saturday
Cheapest Buses Saturday
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FlixBus14h 15m003:50PragueWilsonova Coach Station18:05BrusselsNorth Station0EconomyA Bus from FlixBus goes from Wilsonova Coach Station, Prague (Czech Republic) at 08/02/2026 03:50:00 to North Station, Brussels (Belgium) arriving at 08/02/2026 18:05:00. 50 Economy ticket for £41 per person are available. Travel duration is 14h 15m
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FlixBus13h 55m004:10PragueNa Knížecí Station18:05BrusselsNorth Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 08/02/2026 04:10:00 to North Station, Brussels (Belgium) arriving at 08/02/2026 18:05:00. 50 Economy ticket for £41 per person are available. Travel duration is 13h 55m
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FlixBus13h 20m011:05PragueÚAN Florenc00:25BrusselsNorth Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 08/02/2026 11:05:00 to North Station, Brussels (Belgium) arriving at 09/02/2026 00:25:00. 50 Economy ticket for £42 per person are available. Travel duration is 13h 20m
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European Sleeper15h 27m018:00PragueWilsonova Coach Station09:27BrusselsMidi Bus Station0EconomyA Bus from European Sleeper goes from Wilsonova Coach Station, Prague (Czech Republic) at 08/02/2026 18:00:00 to Midi Bus Station, Brussels (Belgium) arriving at 09/02/2026 09:27:00. 50 Economy ticket for £208 per person are available. Travel duration is 15h 27m
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Smartwings21h 15m016:30Prague AirportPrague Airport - T1/213:45Antwerp AirportAntwerp Airport0EconomyA Flight from Smartwings goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 08/02/2026 16:30:00 to Antwerp Airport, Antwerp Airport (Belgium) arriving at 09/02/2026 13:45:00. 50 Economy ticket for £111 per person are available. Travel duration is 21h 15m
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Smartwings31h 45m006:00Prague AirportPrague Airport - T1/213:45Antwerp AirportAntwerp Airport0EconomyA Flight from Smartwings goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 08/02/2026 06:00:00 to Antwerp Airport, Antwerp Airport (Belgium) arriving at 09/02/2026 13:45:00. 50 Economy ticket for £123 per person are available. Travel duration is 31h 45m
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Ryanair18h 15m019:30Prague AirportPrague Airport - T1/213:45Antwerp AirportAntwerp Airport0EconomyA Flight from Ryanair goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 08/02/2026 19:30:00 to Antwerp Airport, Antwerp Airport (Belgium) arriving at 09/02/2026 13:45:00. 50 Economy ticket for £130 per person are available. Travel duration is 18h 15m
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Ryanair26h 40m011:05Prague AirportPrague Airport - T1/213:45Antwerp AirportAntwerp Airport0EconomyA Flight from Ryanair goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 08/02/2026 11:05:00 to Antwerp Airport, Antwerp Airport (Belgium) arriving at 09/02/2026 13:45:00. 50 Economy ticket for £160 per person are available. Travel duration is 26h 40m
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Bringer Air Cargo Taxi Aereo29h 30m008:15Prague AirportPrague Airport - T1/213:45Antwerp AirportAntwerp Airport0EconomyA Flight from Bringer Air Cargo Taxi Aereo goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 08/02/2026 08:15:00 to Antwerp Airport, Antwerp Airport (Belgium) arriving at 09/02/2026 13:45:00. 50 Economy ticket for £179 per person are available. Travel duration is 29h 30m
Cheapest Buses Sunday
Cheapest Flights Sunday
What are the fastest trips from Prague to Brussels?
You can get to Brussels from Prague in just 1h 30m with a Flight from Buzz. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
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Smartwings7h 45m006:00Prague AirportPrague Airport - T1/213:45Antwerp AirportAntwerp Airport0EconomyA Flight from Smartwings goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 02/02/2026 06:00:00 to Antwerp Airport, Antwerp Airport (Belgium) arriving at 02/02/2026 13:45:00. 50 Economy ticket for £114 per person are available. Travel duration is 7h 45m
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Ryanair23h 10m013:55Prague AirportPrague Airport - T1/213:05Antwerp AirportAntwerp Airport0EconomyA Flight from Ryanair goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 02/02/2026 13:55:00 to Antwerp Airport, Antwerp Airport (Belgium) arriving at 03/02/2026 13:05:00. 50 Economy ticket for £131 per person are available. Travel duration is 23h 10m
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EasyJet Airline26h 10m010:55Prague AirportPrague Airport - T1/213:05Antwerp AirportAntwerp Airport0EconomyA Flight from EasyJet Airline goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 02/02/2026 10:55:00 to Antwerp Airport, Antwerp Airport (Belgium) arriving at 03/02/2026 13:05:00. 50 Economy ticket for £155 per person are available. Travel duration is 26h 10m
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Buzz26h 20m010:45Prague AirportPrague Airport - T1/213:05Antwerp AirportAntwerp Airport0EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 02/02/2026 10:45:00 to Antwerp Airport, Antwerp Airport (Belgium) arriving at 03/02/2026 13:05:00. 50 Economy ticket for £148 per person are available. Travel duration is 26h 20m
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Skyscanner27h 25m009:40Prague AirportPrague Airport - T1/213:05Antwerp AirportAntwerp Airport0EconomyA Flight from Skyscanner goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 02/02/2026 09:40:00 to Antwerp Airport, Antwerp Airport (Belgium) arriving at 03/02/2026 13:05:00. 50 Economy ticket for £155 per person are available. Travel duration is 27h 25m
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FlixBus13h 20m011:05PragueÚAN Florenc00:25BrusselsNorth Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 02/02/2026 11:05:00 to North Station, Brussels (Belgium) arriving at 03/02/2026 00:25:00. 50 Economy ticket for £44 per person are available. Travel duration is 13h 20m
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FlixBus15h 5m016:15PragueÚAN Florenc07:20BrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 02/02/2026 16:15:00 to Midi Bus Station, Brussels (Belgium) arriving at 03/02/2026 07:20:00. 50 Economy ticket for £47 per person are available. Travel duration is 15h 5m
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FlixBus15h 35m008:50Prague AirportPrague Airport - T1/200:25BrusselsNorth Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 02/02/2026 08:50:00 to North Station, Brussels (Belgium) arriving at 03/02/2026 00:25:00. 50 Economy ticket for £48 per person are available. Travel duration is 15h 35m
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FlixBus19h 30m022:45Prague AirportPrague Airport - T1/218:15BrusselsNorth Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 02/02/2026 22:45:00 to North Station, Brussels (Belgium) arriving at 03/02/2026 18:15:00. 50 Economy ticket for £45 per person are available. Travel duration is 19h 30m
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FlixBus20h 0m011:20Prague AirportPrague Airport - T1/207:20BrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 02/02/2026 11:20:00 to Midi Bus Station, Brussels (Belgium) arriving at 03/02/2026 07:20:00. 50 Economy ticket for £49 per person are available. Travel duration is 20h 0m
Fastest Flights Monday
Fastest Buses Monday
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FlixBus13h 20m011:05PragueÚAN Florenc00:25BrusselsNorth Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 03/02/2026 11:05:00 to North Station, Brussels (Belgium) arriving at 04/02/2026 00:25:00. 50 Economy ticket for £42 per person are available. Travel duration is 13h 20m
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FlixBus15h 5m016:15PragueÚAN Florenc07:20BrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 03/02/2026 16:15:00 to Midi Bus Station, Brussels (Belgium) arriving at 04/02/2026 07:20:00. 50 Economy ticket for £46 per person are available. Travel duration is 15h 5m
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FlixBus15h 35m008:50Prague AirportPrague Airport - T1/200:25BrusselsNorth Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 03/02/2026 08:50:00 to North Station, Brussels (Belgium) arriving at 04/02/2026 00:25:00. 50 Economy ticket for £44 per person are available. Travel duration is 15h 35m
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European Sleeper16h 28m018:00PragueWilsonova Coach Station10:28BrusselsMidi Bus Station0EconomyA Bus from European Sleeper goes from Wilsonova Coach Station, Prague (Czech Republic) at 03/02/2026 18:00:00 to Midi Bus Station, Brussels (Belgium) arriving at 04/02/2026 10:28:00. 50 Economy ticket for £208 per person are available. Travel duration is 16h 28m
Fastest Buses Tuesday
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FlixBus13h 20m011:05PragueÚAN Florenc00:25BrusselsNorth Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 04/02/2026 11:05:00 to North Station, Brussels (Belgium) arriving at 05/02/2026 00:25:00. 50 Economy ticket for £36 per person are available. Travel duration is 13h 20m
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FlixBus15h 5m016:15PragueÚAN Florenc07:20BrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 04/02/2026 16:15:00 to Midi Bus Station, Brussels (Belgium) arriving at 05/02/2026 07:20:00. 50 Economy ticket for £38 per person are available. Travel duration is 15h 5m
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FlixBus15h 35m008:50Prague AirportPrague Airport - T1/200:25BrusselsNorth Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 04/02/2026 08:50:00 to North Station, Brussels (Belgium) arriving at 05/02/2026 00:25:00. 50 Economy ticket for £38 per person are available. Travel duration is 15h 35m
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FlixBus17h 45m022:45Prague AirportPrague Airport - T1/216:30BrusselsNorth Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 04/02/2026 22:45:00 to North Station, Brussels (Belgium) arriving at 05/02/2026 16:30:00. 50 Economy ticket for £40 per person are available. Travel duration is 17h 45m
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FlixBus18h 45m008:50Prague AirportPrague Airport - T1/203:35BrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 04/02/2026 08:50:00 to Midi Bus Station, Brussels (Belgium) arriving at 05/02/2026 03:35:00. 50 Economy ticket for £38 per person are available. Travel duration is 18h 45m
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Smartwings21h 15m016:30Prague AirportPrague Airport - T1/213:45Antwerp AirportAntwerp Airport0EconomyA Flight from Smartwings goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 04/02/2026 16:30:00 to Antwerp Airport, Antwerp Airport (Belgium) arriving at 05/02/2026 13:45:00. 50 Economy ticket for £103 per person are available. Travel duration is 21h 15m
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Air Bagan25h 25m019:15Prague AirportPrague Airport - T1/220:40Antwerp AirportAntwerp Airport0EconomyA Flight from Air Bagan goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 04/02/2026 19:15:00 to Antwerp Airport, Antwerp Airport (Belgium) arriving at 05/02/2026 20:40:00. 50 Economy ticket for £139 per person are available. Travel duration is 25h 25m
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Ryanair27h 45m010:00Prague AirportPrague Airport - T1/213:45Antwerp AirportAntwerp Airport0EconomyA Flight from Ryanair goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 04/02/2026 10:00:00 to Antwerp Airport, Antwerp Airport (Belgium) arriving at 05/02/2026 13:45:00. 50 Economy ticket for £103 per person are available. Travel duration is 27h 45m
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Wizz Air29h 40m008:05Prague AirportPrague Airport - T1/213:45Antwerp AirportAntwerp Airport0EconomyA Flight from Wizz Air goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 04/02/2026 08:05:00 to Antwerp Airport, Antwerp Airport (Belgium) arriving at 05/02/2026 13:45:00. 50 Economy ticket for £96 per person are available. Travel duration is 29h 40m
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Buzz31h 45m006:00Prague AirportPrague Airport - T1/213:45Antwerp AirportAntwerp Airport0EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 04/02/2026 06:00:00 to Antwerp Airport, Antwerp Airport (Belgium) arriving at 05/02/2026 13:45:00. 50 Economy ticket for £113 per person are available. Travel duration is 31h 45m
Fastest Buses Wednesday
Fastest Flights Wednesday
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Smartwings1h 30m006:40Prague AirportPrague Airport08:10Brussels AirportBrussels Airport0EconomyA Flight from Smartwings goes from Prague Airport, Prague Airport (Czech Republic) at 05/02/2026 06:40:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 05/02/2026 08:10:00. 50 Economy ticket for £53 per person are available. Travel duration is 1h 30m
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Brussels Airlines1h 35m006:50Prague AirportPrague Airport08:25Brussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Prague Airport, Prague Airport (Czech Republic) at 05/02/2026 06:50:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 05/02/2026 08:25:00. 50 Economy ticket for £160 per person are available. Travel duration is 1h 35m
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Swiss International Air Lines3h 35m010:00Prague AirportPrague Airport13:35Brussels AirportBrussels Airport0EconomyA Flight from Swiss International Air Lines goes from Prague Airport, Prague Airport (Czech Republic) at 05/02/2026 10:00:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 05/02/2026 13:35:00. 50 Economy ticket for £160 per person are available. Travel duration is 3h 35m
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Smartwings7h 45m006:00Prague AirportPrague Airport - T1/213:45Antwerp AirportAntwerp Airport0EconomyA Flight from Smartwings goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 05/02/2026 06:00:00 to Antwerp Airport, Antwerp Airport (Belgium) arriving at 05/02/2026 13:45:00. 50 Economy ticket for £122 per person are available. Travel duration is 7h 45m
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EasyJet Airline11h 30m021:10Prague AirportPrague Airport08:40Brussels AirportBrussels Airport0EconomyA Flight from EasyJet Airline goes from Prague Airport, Prague Airport (Czech Republic) at 05/02/2026 21:10:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 06/02/2026 08:40:00. 50 Economy ticket for £108 per person are available. Travel duration is 11h 30m
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Vueling Airlines11h 45m021:10Prague AirportPrague Airport08:55Brussels AirportBrussels Airport0EconomyA Flight from Vueling Airlines goes from Prague Airport, Prague Airport (Czech Republic) at 05/02/2026 21:10:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 06/02/2026 08:55:00. 50 Economy ticket for £154 per person are available. Travel duration is 11h 45m
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FlixBus13h 20m011:05PragueÚAN Florenc00:25BrusselsNorth Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 05/02/2026 11:05:00 to North Station, Brussels (Belgium) arriving at 06/02/2026 00:25:00. 50 Economy ticket for £38 per person are available. Travel duration is 13h 20m
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FlixBus13h 55m004:10PragueNa Knížecí Station18:05BrusselsNorth Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 05/02/2026 04:10:00 to North Station, Brussels (Belgium) arriving at 05/02/2026 18:05:00. 50 Economy ticket for £38 per person are available. Travel duration is 13h 55m
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FlixBus14h 15m003:50PragueWilsonova Coach Station18:05BrusselsNorth Station0EconomyA Bus from FlixBus goes from Wilsonova Coach Station, Prague (Czech Republic) at 05/02/2026 03:50:00 to North Station, Brussels (Belgium) arriving at 05/02/2026 18:05:00. 50 Economy ticket for £38 per person are available. Travel duration is 14h 15m
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European Sleeper15h 27m018:00PragueWilsonova Coach Station09:27BrusselsMidi Bus Station0EconomyA Bus from European Sleeper goes from Wilsonova Coach Station, Prague (Czech Republic) at 05/02/2026 18:00:00 to Midi Bus Station, Brussels (Belgium) arriving at 06/02/2026 09:27:00. 50 Economy ticket for £213 per person are available. Travel duration is 15h 27m
Fastest Flights Thursday
Fastest Buses Thursday
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FlixBus13h 20m011:05PragueÚAN Florenc00:25BrusselsNorth Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 06/02/2026 11:05:00 to North Station, Brussels (Belgium) arriving at 07/02/2026 00:25:00. 50 Economy ticket for £41 per person are available. Travel duration is 13h 20m
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FlixBus13h 55m004:10PragueNa Knížecí Station18:05BrusselsNorth Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 06/02/2026 04:10:00 to North Station, Brussels (Belgium) arriving at 06/02/2026 18:05:00. 50 Economy ticket for £42 per person are available. Travel duration is 13h 55m
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FlixBus14h 15m003:50PragueWilsonova Coach Station18:05BrusselsNorth Station0EconomyA Bus from FlixBus goes from Wilsonova Coach Station, Prague (Czech Republic) at 06/02/2026 03:50:00 to North Station, Brussels (Belgium) arriving at 06/02/2026 18:05:00. 50 Economy ticket for £42 per person are available. Travel duration is 14h 15m
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FlixBus14h 50m023:05PragueÚAN Florenc13:55BrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 06/02/2026 23:05:00 to Midi Bus Station, Brussels (Belgium) arriving at 07/02/2026 13:55:00. 50 Economy ticket for £44 per person are available. Travel duration is 14h 50m
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FlixBus15h 5m016:15PragueÚAN Florenc07:20BrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 06/02/2026 16:15:00 to Midi Bus Station, Brussels (Belgium) arriving at 07/02/2026 07:20:00. 50 Economy ticket for £44 per person are available. Travel duration is 15h 5m
Fastest Buses Friday
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Buzz1h 30m014:35Prague AirportPrague Airport - T1/216:05Brussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 07/02/2026 14:35:00 to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 07/02/2026 16:05:00. 50 Economy ticket for £34 per person are available. Travel duration is 1h 30m
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Smartwings1h 30m006:40Prague AirportPrague Airport - T1/208:10Brussels AirportBrussels Airport0EconomyA Flight from Smartwings goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 07/02/2026 06:40:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 07/02/2026 08:10:00. 50 Economy ticket for £49 per person are available. Travel duration is 1h 30m
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Ryanair5h 0m015:45Prague AirportPrague Airport - T1/220:45Brussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Ryanair goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 07/02/2026 15:45:00 to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 07/02/2026 20:45:00. 50 Economy ticket for £60 per person are available. Travel duration is 5h 0m
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Skyscanner5h 30m009:20Prague AirportPrague Airport - T1/214:50Brussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Skyscanner goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 07/02/2026 09:20:00 to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 07/02/2026 14:50:00. 50 Economy ticket for £55 per person are available. Travel duration is 5h 30m
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Skyscanner6h 50m014:45Prague AirportPrague Airport - T1/221:35Brussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Skyscanner goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 07/02/2026 14:45:00 to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 07/02/2026 21:35:00. 50 Economy ticket for £52 per person are available. Travel duration is 6h 50m
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Ryanair11h 5m022:00Prague AirportPrague Airport - T1/209:05Brussels AirportBrussels Airport0EconomyA Flight from Ryanair goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 07/02/2026 22:00:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 08/02/2026 09:05:00. 50 Economy ticket for £57 per person are available. Travel duration is 11h 5m
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FlixBus13h 20m010:35PragueÚAN Florenc23:55BrusselsNorth Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 07/02/2026 10:35:00 to North Station, Brussels (Belgium) arriving at 07/02/2026 23:55:00. 50 Economy ticket for £39 per person are available. Travel duration is 13h 20m
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FlixBus13h 55m004:10PragueNa Knížecí Station18:05BrusselsNorth Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 07/02/2026 04:10:00 to North Station, Brussels (Belgium) arriving at 07/02/2026 18:05:00. 50 Economy ticket for £41 per person are available. Travel duration is 13h 55m
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FlixBus14h 15m003:50PragueWilsonova Coach Station18:05BrusselsNorth Station0EconomyA Bus from FlixBus goes from Wilsonova Coach Station, Prague (Czech Republic) at 07/02/2026 03:50:00 to North Station, Brussels (Belgium) arriving at 07/02/2026 18:05:00. 50 Economy ticket for £41 per person are available. Travel duration is 14h 15m
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FlixBus15h 5m008:50Prague AirportPrague Airport - T1/223:55BrusselsNorth Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 07/02/2026 08:50:00 to North Station, Brussels (Belgium) arriving at 07/02/2026 23:55:00. 50 Economy ticket for £43 per person are available. Travel duration is 15h 5m
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FlixBus15h 5m016:15PragueÚAN Florenc07:20BrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 07/02/2026 16:15:00 to Midi Bus Station, Brussels (Belgium) arriving at 08/02/2026 07:20:00. 50 Economy ticket for £44 per person are available. Travel duration is 15h 5m
Fastest Flights Saturday
Fastest Buses Saturday
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FlixBus13h 20m011:05PragueÚAN Florenc00:25BrusselsNorth Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 08/02/2026 11:05:00 to North Station, Brussels (Belgium) arriving at 09/02/2026 00:25:00. 50 Economy ticket for £42 per person are available. Travel duration is 13h 20m
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FlixBus13h 55m004:10PragueNa Knížecí Station18:05BrusselsNorth Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 08/02/2026 04:10:00 to North Station, Brussels (Belgium) arriving at 08/02/2026 18:05:00. 50 Economy ticket for £41 per person are available. Travel duration is 13h 55m
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FlixBus14h 15m003:50PragueWilsonova Coach Station18:05BrusselsNorth Station0EconomyA Bus from FlixBus goes from Wilsonova Coach Station, Prague (Czech Republic) at 08/02/2026 03:50:00 to North Station, Brussels (Belgium) arriving at 08/02/2026 18:05:00. 50 Economy ticket for £41 per person are available. Travel duration is 14h 15m
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European Sleeper15h 27m018:00PragueWilsonova Coach Station09:27BrusselsMidi Bus Station0EconomyA Bus from European Sleeper goes from Wilsonova Coach Station, Prague (Czech Republic) at 08/02/2026 18:00:00 to Midi Bus Station, Brussels (Belgium) arriving at 09/02/2026 09:27:00. 50 Economy ticket for £208 per person are available. Travel duration is 15h 27m
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Ryanair18h 15m019:30Prague AirportPrague Airport - T1/213:45Antwerp AirportAntwerp Airport0EconomyA Flight from Ryanair goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 08/02/2026 19:30:00 to Antwerp Airport, Antwerp Airport (Belgium) arriving at 09/02/2026 13:45:00. 50 Economy ticket for £130 per person are available. Travel duration is 18h 15m
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Smartwings21h 15m016:30Prague AirportPrague Airport - T1/213:45Antwerp AirportAntwerp Airport0EconomyA Flight from Smartwings goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 08/02/2026 16:30:00 to Antwerp Airport, Antwerp Airport (Belgium) arriving at 09/02/2026 13:45:00. 50 Economy ticket for £111 per person are available. Travel duration is 21h 15m
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Ryanair26h 40m011:05Prague AirportPrague Airport - T1/213:45Antwerp AirportAntwerp Airport0EconomyA Flight from Ryanair goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 08/02/2026 11:05:00 to Antwerp Airport, Antwerp Airport (Belgium) arriving at 09/02/2026 13:45:00. 50 Economy ticket for £160 per person are available. Travel duration is 26h 40m
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Bringer Air Cargo Taxi Aereo29h 30m008:15Prague AirportPrague Airport - T1/213:45Antwerp AirportAntwerp Airport0EconomyA Flight from Bringer Air Cargo Taxi Aereo goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 08/02/2026 08:15:00 to Antwerp Airport, Antwerp Airport (Belgium) arriving at 09/02/2026 13:45:00. 50 Economy ticket for £179 per person are available. Travel duration is 29h 30m
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Smartwings31h 45m006:00Prague AirportPrague Airport - T1/213:45Antwerp AirportAntwerp Airport0EconomyA Flight from Smartwings goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 08/02/2026 06:00:00 to Antwerp Airport, Antwerp Airport (Belgium) arriving at 09/02/2026 13:45:00. 50 Economy ticket for £123 per person are available. Travel duration is 31h 45m
Fastest Buses Sunday
Fastest Flights Sunday
Here you will find all operators and timetables for a
Bus from Prague to Brussels
What are the most popular stations in Prague and Brussels?
In Prague, you will usually depart from Wilsonova Coach Station, ÚAN Florenc or Černý Most, while in Brussels you will be arriving at Midi Bus Station, North Station or Gare Centrale, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Brussels from Prague? With 10 connections between 2 Flight and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Prague and Brussels, you can pay as low as £34 with a Flight from Buzz.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Buzz: you will get to Brussels in just 1h 30m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Prague and Brussels are FlixBus, Smartwings and Ryanair, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Prague and Brussels is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Horoměřice or to Saint-Gilles, and look at flights from Prague Airport, and landing at Brussels South Charleroi Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Prague to Brussels?
The most popular companies between Prague and Brussels, are FlixBus, Smartwings and Ryanair. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: FlixBus and European Sleeper
Airlines: Smartwings, Ryanair, Buzz and 13 more.
All you need to know when you travel from Prague to Brussels
Check all information on comfort and services on all modes of transports from Prague to Brussels. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Prague to Brussels
How can I reach Brussels from Prague?
Every day, there are on average 10 connections between Flight and Bus, with which you can get to Brussels from Prague.
How far is Brussels from Prague?
The distance between Prague and Brussels is 718.5 km.
What is the most ecofriendly mode of transport between Prague and Brussels?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 19 kgs of CO2, a train 25 kgs, a car 122 kgs, and a flight 177 kgs.
What is the cheapest mode of transport from Prague to Brussels?
You can get to Brussels with just £34 by taking a Flight from Buzz.
What is the fastest way to get from Prague to Brussels?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Brussels in just 1h 30m with a Flight from Buzz.
More routes to Prague and to Brussels
Looking for more options? Here you can see the most popular routes to Prague and to Brussels. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Prague
- Amsterdam to Prague
- Berlin to Prague
- Bratislava to Prague
- Brno to Prague
- Budapest to Prague
- Dresden to Prague
- Florence to Prague
- Karlovy Vary to Prague
- Katowice to Prague
- Krakow to Prague
- Leipzig to Prague
- Linz to Prague
- London to Prague
- Lyon to Prague
- Milan to Prague
- Minsk to Prague
- Munich to Prague
- Nuremberg to Prague
- Regensburg to Prague
- Szczecin to Prague
- Třebíč to Prague
- Venice to Prague
- Vienna to Prague
- Zurich to Prague
- Trips to Brussels
- Amsterdam to Brussels
- Beauvais to Brussels
- Berlin to Brussels
- Bruges (BE) to Brussels
- Cologne to Brussels
- Cologne/Bonn Airport to Brussels
- Eindhoven to Brussels
- Frankfurt am Main to Brussels
- Geneva to Brussels
- Glasgow to Brussels
- Hamburg to Brussels
- Leeds to Brussels
- London to Brussels
- Madrid to Brussels
- Milan to Brussels
- Montpellier to Brussels
- Munich to Brussels
- Münster to Brussels
- Paris to Brussels
- Porto to Brussels
- Rotterdam to Brussels
- Salzburg to Brussels
- Vienna to Brussels
- Zagreb to Brussels
