How to get from Prague to Brussels

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What is the best way to travel from Prague to Brussels?

Looking for a trip? Check and compare all the available Buses and Flights to Brussels from Prague. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 4 available companies to find your perfect trip!
Flight is the cheapest and fastest way on this route
Transport type
Travel time
Cheapest price
Average price
Daily departures
Bus
13h 20m
£61
£123
49
Flight
1h 30m
£57
£177
65

What is the cheapest way to reach Brussels from Prague?

You can reach Brussels with just £57 by taking a Flight from EasyJet Airline, but there are many more cheap offers: we have selected the best ones for you for the next few days here.

Friday
from £76
Saturday
from £69
Sunday
from £57
Monday
from £67
Tuesday
from £69
Wednesday
from £61
Thursday
from £61

    Cheapest Buses Friday

  • FlixBus
    14h 50m
    0
    23:05
    Prague
    ÚAN Florenc
    13:55
    Brussels
    Midi Bus Station
    0
    FlixBus
    Economy
    £76
  • FlixBus
    18h 50m
    0
    14:30
    Prague
    Černý Most
    09:20
    Brussels
    North Station
    0
    FlixBus
    Economy
    £77
  • FlixBus
    19h 5m
    0
    18:50
    Prague Airport
    Prague Airport - T1/2
    13:55
    Brussels
    Midi Bus Station
    0
    FlixBus
    Economy
    £80
  • FlixBus
    15h 25m
    0
    18:00
    Prague
    ÚAN Florenc
    09:25
    Brussels
    North Station
    0
    FlixBus
    Economy
    £83
  • FlixBus
    15h 40m
    0
    17:45
    Prague
    Wilsonova Coach Station
    09:25
    Brussels
    North Station
    0
    FlixBus
    Economy
    £83

    Cheapest Buses Saturday

  • FlixBus
    13h 20m
    0
    10:35
    Prague
    ÚAN Florenc
    23:55
    Brussels
    North Station
    0
    FlixBus
    Economy
    £69
  • FlixBus
    14h 15m
    0
    03:50
    Prague
    Wilsonova Coach Station
    18:05
    Brussels
    North Station
    0
    FlixBus
    Economy
    £73
  • FlixBus
    13h 55m
    0
    04:10
    Prague
    Na Knížecí Station
    18:05
    Brussels
    North Station
    0
    FlixBus
    Economy
    £73
  • FlixBus
    14h 40m
    0
    09:15
    Prague Airport
    Prague Airport - T1/2
    23:55
    Brussels
    North Station
    0
    FlixBus
    Economy
    £73
  • FlixBus
    19h 40m
    0
    16:45
    Prague
    Wilsonova Coach Station
    12:25
    Brussels
    Heysel
    0
    FlixBus
    Economy
    £80
  • Cheapest Flights Saturday

  • Ryanair
    21h 20m
    0
    15:45
    Prague Airport
    Prague Airport - T1/2
    13:05
    Antwerp Airport
    Antwerp Airport
    0
    Ryanair
    Economy
    from £159
  • Buzz
    31h 5m
    0
    06:00
    Prague Airport
    Prague Airport - T1/2
    13:05
    Antwerp Airport
    Antwerp Airport
    0
    Buzz
    Economy
    from £171
  • Skyscanner
    27h 45m
    0
    09:20
    Prague Airport
    Prague Airport - T1/2
    13:05
    Antwerp Airport
    Antwerp Airport
    0
    Skyscanner
    Economy
    from £175
  • Volotea
    15h 25m
    0
    21:40
    Prague Airport
    Prague Airport - T1/2
    13:05
    Antwerp Airport
    Antwerp Airport
    0
    Volotea
    Economy
    from £186
  • EasyJet Airline
    26h 10m
    0
    10:55
    Prague Airport
    Prague Airport - T1/2
    13:05
    Antwerp Airport
    Antwerp Airport
    0
    EasyJet Airline
    Economy
    from £192

    Cheapest Flights Sunday

  • EasyJet Airline
    12h 15m
    0
    08:30
    Prague Airport
    Prague Airport - T1/2
    20:45
    Brussels South Charleroi Airport
    Brussels South Charleroi Airport
    0
    EasyJet Airline
    Economy
    from £57
  • Skyscanner
    12h 45m
    0
    08:00
    Prague Airport
    Prague Airport - T1/2
    20:45
    Brussels South Charleroi Airport
    Brussels South Charleroi Airport
    0
    Skyscanner
    Economy
    from £62
  • EasyJet Airline
    12h 5m
    0
    08:30
    Prague Airport
    Prague Airport - T1/2
    20:35
    Brussels Airport
    Brussels Airport
    0
    EasyJet Airline
    Economy
    from £64
  • Skyscanner
    5h 30m
    0
    08:00
    Prague Airport
    Prague Airport - T1/2
    13:30
    Brussels South Charleroi Airport
    Brussels South Charleroi Airport
    0
    Skyscanner
    Economy
    from £67
  • Buzz
    4h 5m
    0
    07:40
    Prague Airport
    Prague Airport - T1/2
    11:45
    Brussels South Charleroi Airport
    Brussels South Charleroi Airport
    0
    Buzz
    Economy
    from £86
  • Buzz
    4h 10m
    0
    18:20
    Prague Airport
    Prague Airport - T1/2
    22:30
    Brussels South Charleroi Airport
    Brussels South Charleroi Airport
    0
    Buzz
    Economy
    from £86
  • Cheapest Buses Sunday

  • FlixBus
    13h 20m
    0
    11:05
    Prague
    ÚAN Florenc
    00:25
    Brussels
    North Station
    0
    FlixBus
    Economy
    £73
  • FlixBus
    19h 40m
    0
    22:25
    Prague
    Zličín
    18:05
    Brussels
    North Station
    0
    FlixBus
    Economy
    £73
  • FlixBus
    14h 15m
    0
    03:50
    Prague
    Wilsonova Coach Station
    18:05
    Brussels
    North Station
    0
    FlixBus
    Economy
    £76
  • European Sleeper
    15h 27m
    0
    18:00
    Prague
    Train station Wilsonova
    09:27
    Brussels
    Midi Bus Station
    0
    European Sleeper
    Economy
    £228
  • European Sleeper
    15h 27m
    0
    18:00
    Prague
    Wilsonova Coach Station
    09:27
    Brussels
    Midi Bus Station
    0
    European Sleeper
    Economy
    £832

    Cheapest Buses Monday

  • FlixBus
    13h 20m
    0
    11:05
    Prague
    ÚAN Florenc
    00:25
    Brussels
    North Station
    0
    FlixBus
    Economy
    £67
  • FlixBus
    19h 40m
    0
    16:45
    Prague
    Wilsonova Coach Station
    12:25
    Brussels
    Heysel
    0
    FlixBus
    Economy
    £67
  • FlixBus
    15h 35m
    0
    08:50
    Prague Airport
    Prague Airport - T1/2
    00:25
    Brussels
    North Station
    0
    FlixBus
    Economy
    £70
  • FlixBus
    14h 15m
    0
    03:50
    Prague
    Wilsonova Coach Station
    18:05
    Brussels
    North Station
    0
    FlixBus
    Economy
    £71
  • FlixBus
    13h 55m
    0
    04:10
    Prague
    Na Knížecí Station
    18:05
    Brussels
    North Station
    0
    FlixBus
    Economy
    £71
  • Cheapest Flights Monday

  • Volotea
    35h 30m
    0
    08:35
    Prague Airport
    Prague Airport - T1/2
    20:05
    Antwerp Airport
    Antwerp Airport
    0
    Volotea
    Economy
    from £190
  • Buzz
    7h 50m
    0
    05:55
    Prague Airport
    Prague Airport - T1/2
    13:45
    Antwerp Airport
    Antwerp Airport
    0
    Buzz
    Economy
    from £197
  • EasyJet Airline
    30h 15m
    0
    13:50
    Prague Airport
    Prague Airport - T1/2
    20:05
    Antwerp Airport
    Antwerp Airport
    0
    EasyJet Airline
    Economy
    from £212
  • Smartwings
    7h 45m
    0
    06:00
    Prague Airport
    Prague Airport - T1/2
    13:45
    Antwerp Airport
    Antwerp Airport
    0
    Smartwings
    Economy
    from £215
  • Ryanair
    23h 20m
    0
    20:45
    Prague Airport
    Prague Airport - T1/2
    20:05
    Antwerp Airport
    Antwerp Airport
    0
    Ryanair
    Economy
    from £215

    Cheapest Buses Tuesday

  • FlixBus
    14h 15m
    0
    03:50
    Prague
    Wilsonova Coach Station
    18:05
    Brussels
    North Station
    0
    FlixBus
    Economy
    £69
  • FlixBus
    13h 55m
    0
    04:10
    Prague
    Na Knížecí Station
    18:05
    Brussels
    North Station
    0
    FlixBus
    Economy
    £69
  • FlixBus
    15h 5m
    0
    16:15
    Prague
    ÚAN Florenc
    07:20
    Brussels
    Midi Bus Station
    0
    FlixBus
    Economy
    £73
  • European Sleeper
    15h 27m
    0
    18:00
    Prague
    Wilsonova Coach Station
    09:27
    Brussels
    Midi Bus Station
    0
    European Sleeper
    Economy
    £476
  • Cheapest Flights Tuesday

  • Buzz
    14h 10m
    0
    05:55
    Prague Airport
    Prague Airport - T1/2
    20:05
    Antwerp Airport
    Antwerp Airport
    0
    Buzz
    Economy
    from £221
  • Jet2.com
    29h 35m
    0
    12:45
    Prague Airport
    Prague Airport - T1/2
    18:20
    Antwerp Airport
    Antwerp Airport
    0
    Jet2.com
    Economy
    from £235
  • Ryanair
    30h 45m
    0
    11:35
    Prague Airport
    Prague Airport - T1/2
    18:20
    Antwerp Airport
    Antwerp Airport
    0
    Ryanair
    Economy
    from £251
  • EasyJet Airline
    20h 40m
    0
    21:40
    Prague Airport
    Prague Airport - T1/2
    18:20
    Antwerp Airport
    Antwerp Airport
    0
    EasyJet Airline
    Economy
    from £268
  • Smartwings
    35h 40m
    0
    06:40
    Prague Airport
    Prague Airport - T1/2
    18:20
    Antwerp Airport
    Antwerp Airport
    0
    Smartwings
    Economy
    from £329

    Cheapest Buses Wednesday

  • FlixBus
    14h 50m
    0
    23:05
    Prague
    ÚAN Florenc
    13:55
    Brussels
    Midi Bus Station
    0
    FlixBus
    Economy
    £61
  • FlixBus
    15h 5m
    0
    16:15
    Prague
    ÚAN Florenc
    07:20
    Brussels
    Midi Bus Station
    0
    FlixBus
    Economy
    £63
  • FlixBus
    14h 15m
    0
    03:50
    Prague
    Wilsonova Coach Station
    18:05
    Brussels
    North Station
    0
    FlixBus
    Economy
    £65
  • FlixBus
    13h 55m
    0
    04:10
    Prague
    Na Knížecí Station
    18:05
    Brussels
    North Station
    0
    FlixBus
    Economy
    £65
  • FlixBus
    20h 0m
    0
    11:20
    Prague Airport
    Prague Airport - T1/2
    07:20
    Brussels
    Midi Bus Station
    0
    FlixBus
    Economy
    £67

    Cheapest Buses Thursday

  • FlixBus
    14h 15m
    0
    03:50
    Prague
    Wilsonova Coach Station
    18:05
    Brussels
    North Station
    0
    FlixBus
    Economy
    £61
  • FlixBus
    13h 55m
    0
    04:10
    Prague
    Na Knížecí Station
    18:05
    Brussels
    North Station
    0
    FlixBus
    Economy
    £61
  • FlixBus
    15h 5m
    0
    16:15
    Prague
    ÚAN Florenc
    07:20
    Brussels
    Midi Bus Station
    0
    FlixBus
    Economy
    £63
  • European Sleeper
    15h 27m
    0
    18:00
    Prague
    Wilsonova Coach Station
    09:27
    Brussels
    Midi Bus Station
    0
    European Sleeper
    Economy
    £464
  • Cheapest Flights Thursday

  • Vueling Airlines
    30h 30m
    0
    15:50
    Prague Airport
    Prague Airport - T1/2
    22:20
    Antwerp Airport
    Antwerp Airport
    0
    Vueling Airlines
    Economy
    from £198
  • Air Bagan
    29h 15m
    0
    17:05
    Prague Airport
    Prague Airport - T1/2
    22:20
    Antwerp Airport
    Antwerp Airport
    0
    Air Bagan
    Economy
    from £203
  • Smartwings
    34h 45m
    0
    11:35
    Prague Airport
    Prague Airport - T1/2
    22:20
    Antwerp Airport
    Antwerp Airport
    0
    Smartwings
    Economy
    from £206
  • Transavia France
    25h 40m
    0
    20:40
    Prague Airport
    Prague Airport - T1/2
    22:20
    Antwerp Airport
    Antwerp Airport
    0
    Transavia France
    Economy
    from £298
  • Brussels Airlines
    27h 35m
    0
    18:45
    Prague Airport
    Prague Airport - T1/2
    22:20
    Antwerp Airport
    Antwerp Airport
    0
    Brussels Airlines
    Economy
    from £346

What are the fastest trips from Prague to Brussels?

You can get to Brussels from Prague in just 1h 30m with a Flight from Smartwings. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.

Friday
from 14h 50m
Saturday
from 13h 20m
Sunday
from 1h 30m
Monday
from 7h 45m
Tuesday
from 13h 55m
Wednesday
from 13h 55m
Thursday
from 13h 55m

    Fastest Buses Friday

  • FlixBus
    14h 50m
    0
    23:05
    Prague
    ÚAN Florenc
    13:55
    Brussels
    Midi Bus Station
    0
    FlixBus
    Economy
    £76
  • FlixBus
    15h 25m
    0
    18:00
    Prague
    ÚAN Florenc
    09:25
    Brussels
    North Station
    0
    FlixBus
    Economy
    £83
  • FlixBus
    15h 40m
    0
    17:45
    Prague
    Wilsonova Coach Station
    09:25
    Brussels
    North Station
    0
    FlixBus
    Economy
    £83
  • FlixBus
    18h 50m
    0
    14:30
    Prague
    Černý Most
    09:20
    Brussels
    North Station
    0
    FlixBus
    Economy
    £77
  • FlixBus
    19h 5m
    0
    18:50
    Prague Airport
    Prague Airport - T1/2
    13:55
    Brussels
    Midi Bus Station
    0
    FlixBus
    Economy
    £80

    Fastest Buses Saturday

  • FlixBus
    13h 20m
    0
    10:35
    Prague
    ÚAN Florenc
    23:55
    Brussels
    North Station
    0
    FlixBus
    Economy
    £69
  • FlixBus
    13h 55m
    0
    04:10
    Prague
    Na Knížecí Station
    18:05
    Brussels
    North Station
    0
    FlixBus
    Economy
    £73
  • FlixBus
    14h 15m
    0
    03:50
    Prague
    Wilsonova Coach Station
    18:05
    Brussels
    North Station
    0
    FlixBus
    Economy
    £73
  • FlixBus
    14h 40m
    0
    09:15
    Prague Airport
    Prague Airport - T1/2
    23:55
    Brussels
    North Station
    0
    FlixBus
    Economy
    £73
  • FlixBus
    19h 40m
    0
    16:45
    Prague
    Wilsonova Coach Station
    12:25
    Brussels
    Heysel
    0
    FlixBus
    Economy
    £80
  • Fastest Flights Saturday

  • Volotea
    15h 25m
    0
    21:40
    Prague Airport
    Prague Airport - T1/2
    13:05
    Antwerp Airport
    Antwerp Airport
    0
    Volotea
    Economy
    from £186
  • Ryanair
    21h 20m
    0
    15:45
    Prague Airport
    Prague Airport - T1/2
    13:05
    Antwerp Airport
    Antwerp Airport
    0
    Ryanair
    Economy
    from £159
  • EasyJet Airline
    26h 10m
    0
    10:55
    Prague Airport
    Prague Airport - T1/2
    13:05
    Antwerp Airport
    Antwerp Airport
    0
    EasyJet Airline
    Economy
    from £192
  • Skyscanner
    27h 45m
    0
    09:20
    Prague Airport
    Prague Airport - T1/2
    13:05
    Antwerp Airport
    Antwerp Airport
    0
    Skyscanner
    Economy
    from £175
  • Buzz
    31h 5m
    0
    06:00
    Prague Airport
    Prague Airport - T1/2
    13:05
    Antwerp Airport
    Antwerp Airport
    0
    Buzz
    Economy
    from £171

    Fastest Flights Sunday

  • Smartwings
    1h 30m
    0
    17:15
    Prague Airport
    Prague Airport - T1/2
    18:45
    Brussels Airport
    Brussels Airport
    0
    Smartwings
    Economy
    from £97
  • Buzz
    4h 5m
    0
    07:40
    Prague Airport
    Prague Airport - T1/2
    11:45
    Brussels South Charleroi Airport
    Brussels South Charleroi Airport
    0
    Buzz
    Economy
    from £86
  • Buzz
    4h 10m
    0
    18:20
    Prague Airport
    Prague Airport - T1/2
    22:30
    Brussels South Charleroi Airport
    Brussels South Charleroi Airport
    0
    Buzz
    Economy
    from £86
  • Skyscanner
    5h 30m
    0
    08:00
    Prague Airport
    Prague Airport - T1/2
    13:30
    Brussels South Charleroi Airport
    Brussels South Charleroi Airport
    0
    Skyscanner
    Economy
    from £67
  • LOT Polish Airlines / Polskie Linie Lotnicze
    9h 10m
    0
    09:35
    Prague Airport
    Prague Airport - T1/2
    18:45
    Brussels Airport
    Brussels Airport
    0
    LOT Polish Airlines / Polskie Linie Lotnicze
    Economy
    from £90
  • KLM Cityhopper
    11h 20m
    0
    20:15
    Prague Airport
    Prague Airport - T1/2
    07:35
    Brussels Airport
    Brussels Airport
    0
    KLM Cityhopper
    Economy
    from £122
  • Fastest Buses Sunday

  • FlixBus
    13h 20m
    0
    11:05
    Prague
    ÚAN Florenc
    00:25
    Brussels
    North Station
    0
    FlixBus
    Economy
    £73
  • FlixBus
    14h 15m
    0
    03:50
    Prague
    Wilsonova Coach Station
    18:05
    Brussels
    North Station
    0
    FlixBus
    Economy
    £76
  • European Sleeper
    15h 27m
    0
    18:00
    Prague
    Train station Wilsonova
    09:27
    Brussels
    Midi Bus Station
    0
    European Sleeper
    Economy
    £228
  • European Sleeper
    15h 27m
    0
    18:00
    Prague
    Wilsonova Coach Station
    09:27
    Brussels
    Midi Bus Station
    0
    European Sleeper
    Economy
    £832
  • FlixBus
    19h 40m
    0
    22:25
    Prague
    Zličín
    18:05
    Brussels
    North Station
    0
    FlixBus
    Economy
    £73

    Fastest Flights Monday

  • Smartwings
    7h 45m
    0
    06:00
    Prague Airport
    Prague Airport - T1/2
    13:45
    Antwerp Airport
    Antwerp Airport
    0
    Smartwings
    Economy
    from £215
  • Buzz
    7h 50m
    0
    05:55
    Prague Airport
    Prague Airport - T1/2
    13:45
    Antwerp Airport
    Antwerp Airport
    0
    Buzz
    Economy
    from £197
  • Ryanair
    23h 20m
    0
    20:45
    Prague Airport
    Prague Airport - T1/2
    20:05
    Antwerp Airport
    Antwerp Airport
    0
    Ryanair
    Economy
    from £215
  • EasyJet Airline
    30h 15m
    0
    13:50
    Prague Airport
    Prague Airport - T1/2
    20:05
    Antwerp Airport
    Antwerp Airport
    0
    EasyJet Airline
    Economy
    from £212
  • Volotea
    35h 30m
    0
    08:35
    Prague Airport
    Prague Airport - T1/2
    20:05
    Antwerp Airport
    Antwerp Airport
    0
    Volotea
    Economy
    from £190
  • Fastest Buses Monday

  • FlixBus
    13h 20m
    0
    11:05
    Prague
    ÚAN Florenc
    00:25
    Brussels
    North Station
    0
    FlixBus
    Economy
    £67
  • FlixBus
    13h 55m
    0
    04:10
    Prague
    Na Knížecí Station
    18:05
    Brussels
    North Station
    0
    FlixBus
    Economy
    £71
  • FlixBus
    14h 15m
    0
    03:50
    Prague
    Wilsonova Coach Station
    18:05
    Brussels
    North Station
    0
    FlixBus
    Economy
    £71
  • FlixBus
    15h 35m
    0
    08:50
    Prague Airport
    Prague Airport - T1/2
    00:25
    Brussels
    North Station
    0
    FlixBus
    Economy
    £70
  • FlixBus
    19h 40m
    0
    16:45
    Prague
    Wilsonova Coach Station
    12:25
    Brussels
    Heysel
    0
    FlixBus
    Economy
    £67

    Fastest Buses Tuesday

  • FlixBus
    13h 55m
    0
    04:10
    Prague
    Na Knížecí Station
    18:05
    Brussels
    North Station
    0
    FlixBus
    Economy
    £69
  • FlixBus
    14h 15m
    0
    03:50
    Prague
    Wilsonova Coach Station
    18:05
    Brussels
    North Station
    0
    FlixBus
    Economy
    £69
  • FlixBus
    15h 5m
    0
    16:15
    Prague
    ÚAN Florenc
    07:20
    Brussels
    Midi Bus Station
    0
    FlixBus
    Economy
    £73
  • European Sleeper
    15h 27m
    0
    18:00
    Prague
    Wilsonova Coach Station
    09:27
    Brussels
    Midi Bus Station
    0
    European Sleeper
    Economy
    £476
  • Fastest Flights Tuesday

  • Buzz
    14h 10m
    0
    05:55
    Prague Airport
    Prague Airport - T1/2
    20:05
    Antwerp Airport
    Antwerp Airport
    0
    Buzz
    Economy
    from £221
  • EasyJet Airline
    20h 40m
    0
    21:40
    Prague Airport
    Prague Airport - T1/2
    18:20
    Antwerp Airport
    Antwerp Airport
    0
    EasyJet Airline
    Economy
    from £268
  • Jet2.com
    29h 35m
    0
    12:45
    Prague Airport
    Prague Airport - T1/2
    18:20
    Antwerp Airport
    Antwerp Airport
    0
    Jet2.com
    Economy
    from £235
  • Ryanair
    30h 45m
    0
    11:35
    Prague Airport
    Prague Airport - T1/2
    18:20
    Antwerp Airport
    Antwerp Airport
    0
    Ryanair
    Economy
    from £251
  • Smartwings
    35h 40m
    0
    06:40
    Prague Airport
    Prague Airport - T1/2
    18:20
    Antwerp Airport
    Antwerp Airport
    0
    Smartwings
    Economy
    from £329

    Fastest Buses Wednesday

  • FlixBus
    13h 55m
    0
    04:10
    Prague
    Na Knížecí Station
    18:05
    Brussels
    North Station
    0
    FlixBus
    Economy
    £65
  • FlixBus
    14h 15m
    0
    03:50
    Prague
    Wilsonova Coach Station
    18:05
    Brussels
    North Station
    0
    FlixBus
    Economy
    £65
  • FlixBus
    14h 50m
    0
    23:05
    Prague
    ÚAN Florenc
    13:55
    Brussels
    Midi Bus Station
    0
    FlixBus
    Economy
    £61
  • FlixBus
    15h 5m
    0
    16:15
    Prague
    ÚAN Florenc
    07:20
    Brussels
    Midi Bus Station
    0
    FlixBus
    Economy
    £63
  • FlixBus
    20h 0m
    0
    11:20
    Prague Airport
    Prague Airport - T1/2
    07:20
    Brussels
    Midi Bus Station
    0
    FlixBus
    Economy
    £67

    Fastest Buses Thursday

  • FlixBus
    13h 55m
    0
    04:10
    Prague
    Na Knížecí Station
    18:05
    Brussels
    North Station
    0
    FlixBus
    Economy
    £61
  • FlixBus
    14h 15m
    0
    03:50
    Prague
    Wilsonova Coach Station
    18:05
    Brussels
    North Station
    0
    FlixBus
    Economy
    £61
  • FlixBus
    15h 5m
    0
    16:15
    Prague
    ÚAN Florenc
    07:20
    Brussels
    Midi Bus Station
    0
    FlixBus
    Economy
    £63
  • European Sleeper
    15h 27m
    0
    18:00
    Prague
    Wilsonova Coach Station
    09:27
    Brussels
    Midi Bus Station
    0
    European Sleeper
    Economy
    £464
  • Fastest Flights Thursday

  • Transavia France
    25h 40m
    0
    20:40
    Prague Airport
    Prague Airport - T1/2
    22:20
    Antwerp Airport
    Antwerp Airport
    0
    Transavia France
    Economy
    from £298
  • Brussels Airlines
    27h 35m
    0
    18:45
    Prague Airport
    Prague Airport - T1/2
    22:20
    Antwerp Airport
    Antwerp Airport
    0
    Brussels Airlines
    Economy
    from £346
  • Air Bagan
    29h 15m
    0
    17:05
    Prague Airport
    Prague Airport - T1/2
    22:20
    Antwerp Airport
    Antwerp Airport
    0
    Air Bagan
    Economy
    from £203
  • Vueling Airlines
    30h 30m
    0
    15:50
    Prague Airport
    Prague Airport - T1/2
    22:20
    Antwerp Airport
    Antwerp Airport
    0
    Vueling Airlines
    Economy
    from £198
  • Smartwings
    34h 45m
    0
    11:35
    Prague Airport
    Prague Airport - T1/2
    22:20
    Antwerp Airport
    Antwerp Airport
    0
    Smartwings
    Economy
    from £206
Here you will find all operators and timetables for a Bus from Prague to Brussels

What are the most popular stations in Prague and Brussels?

In Prague, you will usually depart from Wilsonova Coach Station, ÚAN Florenc or Černý Most, while in Brussels you will be arriving at Midi Bus Station, North Station or Gare Centrale, but there are many more stops to explore in both locations.

How do I decide? Some tips and tricks from our experience

Are you having trouble deciding on how to get to Brussels from Prague? With 9 connections between 4 Bus and Flight operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.

Look for the lowest price

Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Prague and Brussels, you can pay as low as £57 with a Flight from EasyJet Airline.

Travel duration

Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Smartwings: you will get to Brussels in just 1h 30m.

Comfort makes all the difference

You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Prague and Brussels are FlixBus, EasyJet Airline and Buzz, but be sure to check what they have to offer!

Save money with deals, and always compare

One last tip? Even if you live in Prague and Brussels is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Horoměřice or to Saint-Gilles, and look at flights from Prague Airport, and landing at Brussels South Charleroi Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!

Which companies offer a trip from Prague to Brussels?

The most popular companies between Prague and Brussels, are FlixBus, EasyJet Airline and Buzz. Be sure to check their seat class offers and the amenities that they provide.

Bus companies: FlixBus and European Sleeper

Airlines: EasyJet Airline, Buzz, Smartwings and 11 more.

All you need to know when you travel from Prague to Brussels

Check all information on comfort and services on all modes of transports from Prague to Brussels. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.

FAQs about the trip from Prague to Brussels

How can I reach Brussels from Prague?

Every day, there are on average 9 connections between Bus and Flight, with which you can get to Brussels from Prague.

How far is Brussels from Prague?

The distance between Prague and Brussels is 718.5 km.

What is the most ecofriendly mode of transport between Prague and Brussels?

Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance. On this particular route, a bus will emit, per person, a total of 19 kgs of CO2, a train 25 kgs, a car 122 kgs, and a flight 177 kgs.

What is the cheapest mode of transport from Prague to Brussels?

You can get to Brussels with just £57 by taking a Flight from EasyJet Airline.

What is the fastest way to get from Prague to Brussels?

While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Brussels in just 1h 30m with a Flight from Smartwings.

More routes to Prague and to Brussels

Looking for more options? Here you can see the most popular routes to Prague and to Brussels. Simply click on a connection, and you’ll find all the details about the route!

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