Which bus from Rome to Siena is the best?
Check the bus schedule for Rome to Siena. Here is a selection of the cheapest coach trips for the next days from bus operators like Itabus, FlixBus or MarinoBus. To see the full timetable for all coaches just use or search and compare.
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 2h 45m | 06:30 | Rome | Tiburtina Bus Station | 09:15 | Siena | Train Station | Economy | £6 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 05/12/2025 06:30:00 to Train Station, Siena (Italy) arriving at 05/12/2025 09:15:00. 50 Economy ticket for £6 per person are available. Travel duration is 2h 45m
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| Itabus | 2h 50m | 12:00 | Rome | Tiburtina Bus Station | 14:50 | Siena | Train Station | Premium Economy | £9 |
A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 05/12/2025 12:00:00 to Train Station, Siena (Italy) arriving at 05/12/2025 14:50:00. 50 Premium Economy ticket for £9 per person are available. Travel duration is 2h 50m
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| Itabus | 2h 50m | 13:15 | Rome | Tiburtina Bus Station | 16:05 | Siena | Train Station | Premium Economy | £9 |
A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 05/12/2025 13:15:00 to Train Station, Siena (Italy) arriving at 05/12/2025 16:05:00. 50 Premium Economy ticket for £9 per person are available. Travel duration is 2h 50m
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| FlixBus | 2h 55m | 08:20 | Rome | Tiburtina Bus Station | 11:15 | Siena | Train Station | Economy | £10 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 05/12/2025 08:20:00 to Train Station, Siena (Italy) arriving at 05/12/2025 11:15:00. 50 Economy ticket for £10 per person are available. Travel duration is 2h 55m
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| MarinoBus | 3h 0m | 13:50 | Rome | Tiburtina Bus Station | 16:50 | Siena | Central Bus Station | Economy | £11 |
A Bus from MarinoBus goes from Tiburtina Bus Station, Rome (Italy) at 05/12/2025 13:50:00 to Central Bus Station, Siena (Italy) arriving at 05/12/2025 16:50:00. 50 Economy ticket for £11 per person are available. Travel duration is 3h 0m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 2h 50m | 15:40 | Rome | Tiburtina Bus Station | 18:30 | Siena | Train Station | Premium Economy | £6 |
A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 06/12/2025 15:40:00 to Train Station, Siena (Italy) arriving at 06/12/2025 18:30:00. 50 Premium Economy ticket for £6 per person are available. Travel duration is 2h 50m
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| Itabus | 2h 50m | 14:00 | Rome | Tiburtina Bus Station | 16:50 | Siena | Train Station | Premium Economy | £8 |
A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 06/12/2025 14:00:00 to Train Station, Siena (Italy) arriving at 06/12/2025 16:50:00. 50 Premium Economy ticket for £8 per person are available. Travel duration is 2h 50m
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| FlixBus | 2h 45m | 15:30 | Rome | Tiburtina Bus Station | 18:15 | Siena | Train Station | Economy | £8 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 06/12/2025 15:30:00 to Train Station, Siena (Italy) arriving at 06/12/2025 18:15:00. 50 Economy ticket for £8 per person are available. Travel duration is 2h 45m
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| FlixBus | 2h 50m | 16:50 | Rome | Tiburtina Bus Station | 19:40 | Siena | Train Station | Economy | £8 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 06/12/2025 16:50:00 to Train Station, Siena (Italy) arriving at 06/12/2025 19:40:00. 50 Economy ticket for £8 per person are available. Travel duration is 2h 50m
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| MarinoBus | 3h 0m | 13:50 | Rome | Tiburtina Bus Station | 16:50 | Siena | Central Bus Station | Economy | £22 |
A Bus from MarinoBus goes from Tiburtina Bus Station, Rome (Italy) at 06/12/2025 13:50:00 to Central Bus Station, Siena (Italy) arriving at 06/12/2025 16:50:00. 50 Economy ticket for £22 per person are available. Travel duration is 3h 0m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 2h 50m | 12:00 | Rome | Tiburtina Coach Station | 14:50 | Siena | Central Bus Station | Basic | £7 |
A Bus from Itabus goes from Tiburtina Coach Station, Rome (Italy) at 07/12/2025 12:00:00 to Central Bus Station, Siena (Italy) arriving at 07/12/2025 14:50:00. 50 Basic ticket for £7 per person are available. Travel duration is 2h 50m
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| Itabus | 2h 50m | 13:15 | Rome | Tiburtina Coach Station | 16:05 | Siena | Central Bus Station | Basic | £7 |
A Bus from Itabus goes from Tiburtina Coach Station, Rome (Italy) at 07/12/2025 13:15:00 to Central Bus Station, Siena (Italy) arriving at 07/12/2025 16:05:00. 50 Basic ticket for £7 per person are available. Travel duration is 2h 50m
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| Itabus | 2h 50m | 14:00 | Rome | Tiburtina Coach Station | 16:50 | Siena | Central Bus Station | Basic | £9 |
A Bus from Itabus goes from Tiburtina Coach Station, Rome (Italy) at 07/12/2025 14:00:00 to Central Bus Station, Siena (Italy) arriving at 07/12/2025 16:50:00. 50 Basic ticket for £9 per person are available. Travel duration is 2h 50m
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| MarinoBus | 3h 0m | 13:50 | Rome | Tiburtina Bus Station | 16:50 | Siena | Train Station | Basic | £11 |
A Bus from MarinoBus goes from Tiburtina Bus Station, Rome (Italy) at 07/12/2025 13:50:00 to Train Station, Siena (Italy) arriving at 07/12/2025 16:50:00. 50 Basic ticket for £11 per person are available. Travel duration is 3h 0m
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| MarinoBus | 3h 10m | 05:35 | Rome | Tiburtina Bus Station | 08:45 | Siena | Train Station | Basic | £20 |
A Bus from MarinoBus goes from Tiburtina Bus Station, Rome (Italy) at 07/12/2025 05:35:00 to Train Station, Siena (Italy) arriving at 07/12/2025 08:45:00. 50 Basic ticket for £20 per person are available. Travel duration is 3h 10m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 2h 45m | 06:30 | Rome | Tiburtina Bus Station | 09:15 | Siena | Train Station | Economy | £8 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 08/12/2025 06:30:00 to Train Station, Siena (Italy) arriving at 08/12/2025 09:15:00. 50 Economy ticket for £8 per person are available. Travel duration is 2h 45m
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| FlixBus | 2h 50m | 07:45 | Rome | Tiburtina Bus Station | 10:35 | Siena | Train Station | Economy | £10 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 08/12/2025 07:45:00 to Train Station, Siena (Italy) arriving at 08/12/2025 10:35:00. 50 Economy ticket for £10 per person are available. Travel duration is 2h 50m
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| MarinoBus | 3h 0m | 13:50 | Rome | Tiburtina Bus Station | 16:50 | Siena | Central Bus Station | Economy | £11 |
A Bus from MarinoBus goes from Tiburtina Bus Station, Rome (Italy) at 08/12/2025 13:50:00 to Central Bus Station, Siena (Italy) arriving at 08/12/2025 16:50:00. 50 Economy ticket for £11 per person are available. Travel duration is 3h 0m
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| MarinoBus | 3h 10m | 05:35 | Rome | Tiburtina Coach Station | 08:45 | Siena | Central Bus Station | Basic | £19 |
A Bus from MarinoBus goes from Tiburtina Coach Station, Rome (Italy) at 08/12/2025 05:35:00 to Central Bus Station, Siena (Italy) arriving at 08/12/2025 08:45:00. 50 Basic ticket for £19 per person are available. Travel duration is 3h 10m
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| Itabus | 2h 50m | 14:00 | Rome | Tiburtina Coach Station | 16:50 | Siena | Central Bus Station | Basic | £23 |
A Bus from Itabus goes from Tiburtina Coach Station, Rome (Italy) at 08/12/2025 14:00:00 to Central Bus Station, Siena (Italy) arriving at 08/12/2025 16:50:00. 50 Basic ticket for £23 per person are available. Travel duration is 2h 50m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 2h 50m | 14:00 | Rome | Tiburtina Bus Station | 16:50 | Siena | Train Station | Premium Economy | £4 |
A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 09/12/2025 14:00:00 to Train Station, Siena (Italy) arriving at 09/12/2025 16:50:00. 50 Premium Economy ticket for £4 per person are available. Travel duration is 2h 50m
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| Itabus | 2h 50m | 15:40 | Rome | Tiburtina Bus Station | 18:30 | Siena | Train Station | Premium Economy | £6 |
A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 09/12/2025 15:40:00 to Train Station, Siena (Italy) arriving at 09/12/2025 18:30:00. 50 Premium Economy ticket for £6 per person are available. Travel duration is 2h 50m
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| FlixBus | 2h 45m | 06:30 | Rome | Tiburtina Bus Station | 09:15 | Siena | Train Station | Economy | £7 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 09/12/2025 06:30:00 to Train Station, Siena (Italy) arriving at 09/12/2025 09:15:00. 50 Economy ticket for £7 per person are available. Travel duration is 2h 45m
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| FlixBus | 2h 45m | 15:30 | Rome | Tiburtina Bus Station | 18:15 | Siena | Train Station | Economy | £7 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 09/12/2025 15:30:00 to Train Station, Siena (Italy) arriving at 09/12/2025 18:15:00. 50 Economy ticket for £7 per person are available. Travel duration is 2h 45m
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| MarinoBus | 3h 0m | 13:50 | Rome | Tiburtina Bus Station | 16:50 | Siena | Central Bus Station | Economy | £11 |
A Bus from MarinoBus goes from Tiburtina Bus Station, Rome (Italy) at 09/12/2025 13:50:00 to Central Bus Station, Siena (Italy) arriving at 09/12/2025 16:50:00. 50 Economy ticket for £11 per person are available. Travel duration is 3h 0m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 2h 50m | 14:00 | Rome | Tiburtina Bus Station | 16:50 | Siena | Piazza Antonio Gramsci | Economy | £5 |
A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 10/12/2025 14:00:00 to Piazza Antonio Gramsci, Siena (Italy) arriving at 10/12/2025 16:50:00. 50 Economy ticket for £5 per person are available. Travel duration is 2h 50m
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| Itabus | 2h 50m | 12:00 | Rome | Tiburtina Bus Station | 14:50 | Siena | Train Station | Premium Economy | £6 |
A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 10/12/2025 12:00:00 to Train Station, Siena (Italy) arriving at 10/12/2025 14:50:00. 50 Premium Economy ticket for £6 per person are available. Travel duration is 2h 50m
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| FlixBus | 2h 45m | 09:25 | Rome | Tiburtina Bus Station | 12:10 | Siena | Train Station | Economy | £7 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 10/12/2025 09:25:00 to Train Station, Siena (Italy) arriving at 10/12/2025 12:10:00. 50 Economy ticket for £7 per person are available. Travel duration is 2h 45m
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| FlixBus | 2h 45m | 14:30 | Rome | Tiburtina Bus Station | 17:15 | Siena | Train Station | Economy | £8 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 10/12/2025 14:30:00 to Train Station, Siena (Italy) arriving at 10/12/2025 17:15:00. 50 Economy ticket for £8 per person are available. Travel duration is 2h 45m
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| MarinoBus | 3h 0m | 13:50 | Rome | Tiburtina Bus Station | 16:50 | Siena | Central Bus Station | Economy | £11 |
A Bus from MarinoBus goes from Tiburtina Bus Station, Rome (Italy) at 10/12/2025 13:50:00 to Central Bus Station, Siena (Italy) arriving at 10/12/2025 16:50:00. 50 Economy ticket for £11 per person are available. Travel duration is 3h 0m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 2h 50m | 12:00 | Rome | Tiburtina Bus Station | 14:50 | Siena | Train Station | Premium Economy | £4 |
A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 11/12/2025 12:00:00 to Train Station, Siena (Italy) arriving at 11/12/2025 14:50:00. 50 Premium Economy ticket for £4 per person are available. Travel duration is 2h 50m
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| Itabus | 2h 50m | 13:15 | Rome | Tiburtina Bus Station | 16:05 | Siena | Train Station | Premium Economy | £4 |
A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 11/12/2025 13:15:00 to Train Station, Siena (Italy) arriving at 11/12/2025 16:05:00. 50 Premium Economy ticket for £4 per person are available. Travel duration is 2h 50m
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| FlixBus | 2h 45m | 06:30 | Rome | Tiburtina Bus Station | 09:15 | Siena | Train Station | Economy | £6 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 11/12/2025 06:30:00 to Train Station, Siena (Italy) arriving at 11/12/2025 09:15:00. 50 Economy ticket for £6 per person are available. Travel duration is 2h 45m
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| FlixBus | 2h 45m | 14:30 | Rome | Tiburtina Bus Station | 17:15 | Siena | Train Station | Economy | £6 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 11/12/2025 14:30:00 to Train Station, Siena (Italy) arriving at 11/12/2025 17:15:00. 50 Economy ticket for £6 per person are available. Travel duration is 2h 45m
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| MarinoBus | 3h 0m | 13:50 | Rome | Tiburtina Bus Station | 16:50 | Siena | Central Bus Station | Economy | £11 |
A Bus from MarinoBus goes from Tiburtina Bus Station, Rome (Italy) at 11/12/2025 13:50:00 to Central Bus Station, Siena (Italy) arriving at 11/12/2025 16:50:00. 50 Economy ticket for £11 per person are available. Travel duration is 3h 0m
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Best Price Offer: The price for the cheapest coach from Rome to Siena is £4 on 09/12/2025. Flexible travellers save on ticket prices.
What is the best day and time to travel by bus between Rome and Siena?
All facts for Rome to Siena bus at a glance
Compare all coach operators like Itabus, FlixBus and MarinoBus that travel daily 51 times by bus from Rome to Siena in one click. Book your Rome to Siena bus ticket starting from £4!
| Cheapest Bus | £4 |
| Fastest Bus | 2h 39m |
| Earliest Coach | 05:35 |
| Latest Coach | 22:15 |
| Daily Bus Connections | 51 Ø |
| Distance | 184.3 km |
| Coach Companies | Itabus, FlixBus and MarinoBus |
What are the cheapest coach tickets from Rome to Siena?
Every day, 51 buses from 3 coach companies leave Rome for Siena. Check the table below to find the cheapest prices for coach tickets for this route, starting from 05/12/2025 and for the following days. Make sure get the cheapest bus ticket!
The cheapest time to travel from Rome to Siena
How to save money travelling from Rome to Siena
Book the ticket from Rome to Siena in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the coach from Rome to Siena, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Rome to Siena are also emptier.Check for bus deals and promotions for all bus companies in this route. On CheckMyBus we show special offers directly in the coach trip on our search. Sign-up and check or deals sections and get notifications on our latest travel hacks.
What are the most popular bus companies from Rome to Siena?
FlixBus from Rome to Siena
Here you will find the key facts about the FlixBus bus route Rome to Siena:
| Cheapest Price | £6 |
| Fastest Coach | 2h 39m |
| Earliest Coach | 06:30 |
| Last Coach | 21:45 |
| Daily Connections | 18 Ø |
| Found on | 04/12/2025 |
Itabus from Rome to Siena
Here you will find the key facts about the Itabus bus route Rome to Siena:
| Cheapest Price | £4 |
| Fastest Coach | 2h 49m |
| Earliest Coach | 12:00 |
| Last Coach | 22:15 |
| Daily Connections | 26 Ø |
| Found on | 04/12/2025 |
All bus stations and stops in Rome and Siena
Here is a map with all coach stations in Rome and Siena. Compare which stop is closest to your destination to save time to find the fastest buses and connections.
Compare the bus with other modes of transport
All you need to know when you travel by bus from Rome to Siena
FAQs for Rome to Siena bus
How much does a Rome Siena coach trip cost?
How much could I save by comparing buses from Rome to Siena?
How many connections are available for the Rome Siena route on average every day?
How long does a bus to Siena from Rome take?
What time is the first bus from Rome to Siena?
What time is the last coach from Rome to Siena?
Which bus companies serve the Rome Siena route?
Is there a direct bus between Rome and Siena?
What can I take with me on the bus to Siena from Rome?
What equipment is available for the Rome Siena bus route?
Available seat classes which are offered on the bus route Rome to Siena
Name referring to the typical seat you will find with companies that don’t distinguish between different classes.
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.
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