Bus tickets Rome to Prague from £49

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Compare all timetables for the bus from Rome to Prague

Here is a selection of the cheapest bus trips from the schedule from Rome to Prague from various bus operators like FlixBus or RegioJet for the next days.

today
£88
tomorrow
£82
Sunday
£79
Monday
£76
Tuesday
£60
Wednesday
£49
Thursday
£65

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 20h 30m 21:00 Rome Tiburtina Bus Station 17:30 Prague Wilsonova Coach Station  Economy £88
FlixBus 24h 50m 17:00 Rome Tiburtina Bus Station 17:50 Prague Na Knížecí Station  Economy £88
FlixBus 20h 45m 21:00 Rome Tiburtina Bus Station 17:45 Prague ÚAN Florenc  Economy £88
FlixBus 24h 20m 17:25 Rome Anagnina Bus Station 17:45 Prague ÚAN Florenc  Economy £90
FlixBus 24h 5m 17:25 Rome Anagnina Bus Station 17:30 Prague Wilsonova Coach Station  Economy £91

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 20h 30m 17:25 Rome Anagnina Bus Station 13:55 Prague Wilsonova Coach Station  Economy £82
FlixBus 20h 40m 17:25 Rome Anagnina Bus Station 14:05 Prague ÚAN Florenc  Economy £82
FlixBus 22h 30m 10:15 Rome Tiburtina Bus Station 08:45 Prague ÚAN Florenc  Economy £83
FlixBus 23h 50m 10:15 Rome Tiburtina Bus Station 10:05 Prague Na Knížecí Station  Economy £83
FlixBus 22h 0m 10:15 Rome Tiburtina Bus Station 08:15 Prague Roztyly  Economy £83

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 25h 35m 01:40 Rome Tiburtina Bus Station 03:15 Prague Wilsonova Coach Station  Economy £79
FlixBus 20h 30m 09:30 Rome Tiburtina Bus Station 06:00 Prague Wilsonova Coach Station  Economy £80
FlixBus 20h 45m 09:30 Rome Tiburtina Bus Station 06:15 Prague ÚAN Florenc  Economy £80
FlixBus 20h 30m 21:00 Rome Tiburtina Bus Station 17:30 Prague Wilsonova Coach Station  Economy £81
FlixBus 20h 45m 21:00 Rome Tiburtina Bus Station 17:45 Prague ÚAN Florenc  Economy £81

Cheapest bus trips Monday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 24h 35m 17:00 Rome Tiburtina Bus Station 17:35 Prague Hradčanská  Economy £76
FlixBus 20h 45m 21:00 Rome Tiburtina Bus Station 17:45 Prague ÚAN Florenc  Economy £77
FlixBus 20h 30m 21:00 Rome Tiburtina Bus Station 17:30 Prague Wilsonova Coach Station  Economy £77
FlixBus 27h 0m 17:00 Rome Tiburtina Bus Station 20:00 Prague Wilsonova Coach Station  Economy £78
FlixBus 24h 30m 21:20 Rome Tiburtina Bus Station 21:50 Prague Wilsonova Coach Station  Economy £80

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 25h 55m 21:00 Rome Tiburtina Bus Station 22:55 Prague Na Knížecí Station  Economy £60
FlixBus 24h 45m 13:05 Rome Anagnina Bus Station 13:50 Prague ÚAN Florenc  Economy £64
FlixBus 24h 35m 13:05 Rome Anagnina Bus Station 13:40 Prague Wilsonova Coach Station  Economy £64
FlixBus 27h 0m 17:00 Rome Tiburtina Bus Station 20:00 Prague Wilsonova Coach Station  Economy £66
FlixBus 20h 30m 21:00 Rome Tiburtina Bus Station 17:30 Prague Wilsonova Coach Station  Economy £66

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
RegioJet 20h 10m 13:00 Rome Tiburtina Bus Station 09:10 Prague ÚAN Florenc  Economy £49
FlixBus 20h 35m 22:55 Rome Tiburtina Bus Station 19:30 Prague ÚAN Florenc  Economy £64
FlixBus 20h 25m 22:55 Rome Tiburtina Bus Station 19:20 Prague Wilsonova Coach Station  Economy £64
FlixBus 27h 25m 23:50 Rome Tiburtina Bus Station 03:15 Prague Wilsonova Coach Station  Economy £64
RegioJet 20h 39m 13:00 Rome Tiburtina Bus Station 09:39 Prague Wilsonova Coach Station  Economy £67

Cheapest bus trips Thursday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 28h 20m 17:00 Rome Tiburtina Bus Station 21:20 Prague Wilsonova Coach Station  Economy £65
FlixBus 20h 45m 09:30 Rome Tiburtina Bus Station 06:15 Prague ÚAN Florenc  Economy £67
FlixBus 20h 30m 09:30 Rome Tiburtina Bus Station 06:00 Prague Wilsonova Coach Station  Economy £67
FlixBus 24h 45m 12:45 Rome Anagnina Bus Station 13:30 Prague Roztyly  Economy £68
FlixBus 24h 45m 07:30 Rome Tiburtina Bus Station 08:15 Prague Roztyly  Economy £69

Best Price Offer: The price for the cheapest coach from Rome to Prague is £49 on 10/12/2025. Flexible travellers save on ticket prices.


Frequency of bus connections between Rome and Prague

See here how frequent the connections between Rome and Prague are, during different times and days of the week.
Saturday is the busiest day, with more than 47 daily coaches from Rome to Prague. Tuesday has instead the fewest connections, with only 16 daily coaches between Rome and Prague.
The busiest time of the day is the Afternoon, with 119 coaches from Rome to Prague, while Night sees the fewest connections between Rome and Prague, with 4 offers.

Facts about coaches from Rome to Prague

Compare all providers like FlixBus and RegioJet that travel 35 times every day by bus from Rome to Prague in one click! Book your bus ticket from Rome to Prague starting from £49!

Cheapest Bus £49
Fastest Bus 20h 10m
Earliest Coach 01:40
Latest Coach 23:50
Daily Bus Connections 35 Ø
Distance 921.0 km
Coach Companies FlixBus and RegioJet

Cheapest coach connections from Rome to Prague

Every day, 35 buses from 2 coach companies leave Rome for Prague: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 05/12/2025 and for the following days.

Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday
Monday 01/12
Tuesday 02/12
Wednesday 03/12
Thursday 04/12
Friday 05/12
£88
Saturday 06/12
£82
Sunday 07/12
£79
Monday 08/12
£76
Tuesday 09/12
£60
Wednesday 10/12
£64
Thursday 11/12
£65
Friday 12/12
£65
Saturday 13/12
£66
Sunday 14/12
£67
Monday 15/12
£64
Tuesday 16/12
£64
Wednesday 17/12
£66
Thursday 18/12
£80
Friday 19/12
£81
Saturday 20/12
£86
Sunday 21/12
£88
Monday 22/12
£88
Tuesday 23/12
£90
Wednesday 24/12
£93
Thursday 25/12
£88
Friday 26/12
£93
Saturday 27/12
£96
Sunday 28/12

The cheapest time to travel from Rome to Prague

See here on which day and which time of the day you can find the cheapest bus ticket from Rome to Prague, for the next 30 days.
With a price starting from £49, Wednesday is the cheapest day for a coach from Rome to Prague. Sunday instead is the most expensive day with prices starting from £67.
Afternoon is the cheapest day time for bus tickets from Rome to Prague, with £49. Morning is the most expensive time of the day with prices starting from £67.

How to save money travelling from Rome to Prague

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Rome to Prague in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Rome to Prague, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Rome to Prague are also emptier.

All bus stations and stops in Rome and Prague

The map below shows you where to find all the bus stations in Rome and Prague.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Rome to Prague? Compare all modes of transports from Rome to Prague.

Service and Comfort on the bus from Rome to Prague

Want to know which seat classes are available on the coaches from Rome to Prague? Or which bus companies serve the route Rome to Prague? Below you will find answers to your questions.

FAQs about the Rome to Prague bus

How much does a Rome - Prague coach trip cost?

This depends on, among other things, the day and travel time. The cheapest ticket for the Rome - Prague bus trip is available from £49 and takes 20h 10m. Compare offers and save money!

How much could I save by comparing buses from Rome to Prague?

The connection Rome to Prague is offered by 2 companies with ticket prices ranging from £49 to £146. Therefore, we suggest booking your ticket as soon as possible to ensure you will get the cheapest ticket price.

How many connections are available for the Rome - Prague route on average every day?

Each day, the bus route from Rome to Prague is offered by roughly 35 busses. By using our search, you can compare bus schedules and find your ideal trip.

How long does a bus to Prague from Rome take?

The quickest coach from Rome to Prague is provided by RegioJet and takes 20h 10m. Coach tickets for this connection cost £49. However, keep in mind that the connection can take longer due to traffic.

What time is the first bus from Rome to Prague?

The earliest bus to Prague departs from Rome at 01:40. In this context, information about departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

What time is the last coach from Rome to Prague?

The latest bus to Prague departs from Rome at 23:50. Please note that departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

Which bus companies serve the Rome - Prague route?

Passengers looking to travel from Rome to Prague can travel with FlixBus and RegioJet. Compare all available bus tickets with our search to book the trip that works best for you.

Is there a direct bus between Rome and Prague?

You can check all the direct connections between Rome and Prague by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and RegioJet.

What can I take with me on the bus to Prague from Rome?

Depending on which provider you travel with, what you are allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the bus for the Rome Prague bus route free of charge. Simply use our search to find a coach that is best suited to your needs for your planned travel date.

What equipment is available for the Rome Prague bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make travelling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Rome to Prague on your planned travel date.

Available seat classes which are offered on the bus route Rome to Prague

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Rome and to Prague

Here’s an overview of the most popular bus routes to Rome and to Prague. Simply click on the connection of your choice, and you will find all the details about your bus route!
Buses Messina to Rome Buses Messina to Rome
Bus from Castrovillari to Rome Bus from Castrovillari to Rome
Buses Crotone to Rome Buses Crotone to Rome
Sibari to Rome bus Sibari to Rome bus
Coaches Florence to Prague Coaches Florence to Prague
Coaches Teplice to Prague Coaches Teplice to Prague
Coach to Prague from Bologna Coach to Prague from Bologna
Coaches Vranov nad Toplou to Prague Coaches Vranov nad Toplou to Prague
Popular Airport Transfers to Rome and to Prague
CheckMyBus › Coaches in Italy › Coach to Rome › Coach to Prague

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