Bus tickets Rome to Prague from £55

Compare all the coach companies and find the best price with CheckMyBus
Search for your destination Millions of deals worldwide
Compare results Save up to 70%
Find the right bus for you Easy and transparent

Compare all timetables for the bus from Rome to Prague

Here is a selection of the cheapest bus trips from the schedule from Rome to Prague from various bus operators like FlixBus for the next days.

today
£110
tomorrow
£76
Tuesday
£73
Wednesday
£67
Thursday
£70
Friday
£68
Saturday
£55

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 23h 10m 17:00 Rome Tiburtina Bus Station 16:10 Prague Černý Most  Economy £110
FlixBus 24h 35m 17:00 Rome Tiburtina Bus Station 17:35 Prague Hradčanská  Economy £119
FlixBus 24h 50m 10:40 Rome Tiburtina Bus Station 11:30 Prague Zličín  Economy £125
FlixBus 22h 10m 21:00 Rome Tiburtina Bus Station 19:10 Prague Na Knížecí Station  Economy £127
FlixBus 20h 20m 17:00 Rome Tiburtina Bus Station 13:20 Prague Wilsonova Coach Station  Economy £128
  • Did you know that if you travel from Rome to Prague via Udine, you can save more than £50? You can find the corresponding connections below.
    • FlixBus
      27h 50m
      0
      17:05
      Rome
      Tiburtina Bus Station
      02:35
      Udine
      Train Station
      0
      FlixBus
      Economy
      £25
      • Waiting Time 8h 15m
    • FlixBus
      10h 5m
      0
      10:50
      Udine
      Train Station
      20:55
      Prague
      ÚAN Florenc
      0
      FlixBus
      Economy
      £35
    Travel time is 7h 30m longer, but you will save £50

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 22h 15m 07:30 Rome Tiburtina Bus Station 05:45 Prague ÚAN Florenc  Economy £76
FlixBus 20h 45m 21:00 Rome Tiburtina Bus Station 17:45 Prague ÚAN Florenc  Economy £76
FlixBus 20h 30m 21:00 Rome Tiburtina Bus Station 17:30 Prague Wilsonova Coach Station  Economy £76
FlixBus 24h 30m 21:20 Rome Tiburtina Bus Station 21:50 Prague Wilsonova Coach Station  Economy £76
FlixBus 24h 35m 17:00 Rome Tiburtina Bus Station 17:35 Prague Hradčanská  Economy £77
  • Did you know that if you travel from Rome to Prague via Udine, you can save more than £16? You can find the corresponding connections below.
    • FlixBus
      27h 50m
      0
      17:05
      Rome
      Tiburtina Bus Station
      02:35
      Udine
      Train Station
      0
      FlixBus
      Economy
      £25
      • Waiting Time 8h 15m
    • FlixBus
      10h 5m
      0
      10:50
      Udine
      Train Station
      20:55
      Prague
      ÚAN Florenc
      0
      FlixBus
      Economy
      £35
    Travel time is 7h 20m longer, but you will save £16

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 21h 30m 09:30 Rome Tiburtina Bus Station 07:00 Prague Wilsonova Coach Station  Economy £73
FlixBus 27h 0m 17:00 Rome Tiburtina Bus Station 20:00 Prague Wilsonova Coach Station  Economy £73
FlixBus 20h 40m 17:05 Rome Tiburtina Bus Station 13:45 Prague Wilsonova Coach Station  Economy £73
FlixBus 21h 40m 09:30 Rome Tiburtina Bus Station 07:10 Prague ÚAN Florenc  Economy £73
FlixBus 20h 50m 17:05 Rome Tiburtina Bus Station 13:55 Prague ÚAN Florenc  Economy £73
  • Did you know that if you travel from Rome to Prague via Udine, you can save more than £13? You can find the corresponding connections below.
    • FlixBus
      27h 50m
      0
      17:05
      Rome
      Tiburtina Bus Station
      02:35
      Udine
      Train Station
      0
      FlixBus
      Economy
      £25
      • Waiting Time 8h 15m
    • FlixBus
      10h 5m
      0
      10:50
      Udine
      Train Station
      20:55
      Prague
      ÚAN Florenc
      0
      FlixBus
      Economy
      £35
    Travel time is 7h 10m longer, but you will save £13

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 20h 20m 13:05 Rome Anagnina Bus Station 09:25 Prague ÚAN Florenc  Economy £67
FlixBus 28h 45m 22:55 Rome Tiburtina Bus Station 03:40 Prague Wilsonova Coach Station  Economy £68
FlixBus 20h 25m 22:55 Rome Tiburtina Bus Station 19:20 Prague Wilsonova Coach Station  Economy £68
FlixBus 24h 0m 22:55 Rome Tiburtina Bus Station 22:55 Prague Na Knížecí Station  Economy £68
FlixBus 20h 35m 22:55 Rome Tiburtina Bus Station 19:30 Prague ÚAN Florenc  Economy £68
  • Did you know that if you travel from Rome to Prague via Udine, you can save more than £7? You can find the corresponding connections below.
    • FlixBus
      27h 50m
      0
      17:05
      Rome
      Tiburtina Bus Station
      02:35
      Udine
      Train Station
      0
      FlixBus
      Economy
      £25
      • Waiting Time 8h 15m
    • FlixBus
      10h 5m
      0
      10:50
      Udine
      Train Station
      20:55
      Prague
      ÚAN Florenc
      0
      FlixBus
      Economy
      £35
    Travel time is 7h 30m longer, but you will save £7

Cheapest bus trips Thursday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 22h 15m 07:30 Rome Tiburtina Bus Station 05:45 Prague ÚAN Florenc  Economy £70
FlixBus 20h 40m 17:05 Rome Tiburtina Bus Station 13:45 Prague Wilsonova Coach Station  Economy £73
FlixBus 20h 50m 17:05 Rome Tiburtina Bus Station 13:55 Prague ÚAN Florenc  Economy £73
FlixBus 23h 25m 09:30 Rome Tiburtina Bus Station 08:55 Prague Na Knížecí Station  Economy £78
FlixBus 21h 30m 09:30 Rome Tiburtina Bus Station 07:00 Prague Wilsonova Coach Station  Economy £81
  • Did you know that if you travel from Rome to Prague via Udine, you can save more than £10? You can find the corresponding connections below.
    • FlixBus
      27h 50m
      0
      17:05
      Rome
      Tiburtina Bus Station
      02:35
      Udine
      Train Station
      0
      FlixBus
      Economy
      £25
      • Waiting Time 8h 15m
    • FlixBus
      10h 5m
      0
      10:50
      Udine
      Train Station
      20:55
      Prague
      ÚAN Florenc
      0
      FlixBus
      Economy
      £35
    Travel time is 7h 10m longer, but you will save £10

Cheapest bus trips Friday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 20h 40m 17:05 Rome Tiburtina Bus Station 13:45 Prague Wilsonova Coach Station  Economy £68
FlixBus 20h 50m 17:05 Rome Tiburtina Bus Station 13:55 Prague ÚAN Florenc  Economy £68
FlixBus 22h 15m 07:30 Rome Tiburtina Bus Station 05:45 Prague ÚAN Florenc  Economy £78
FlixBus 21h 30m 09:30 Rome Tiburtina Bus Station 07:00 Prague Wilsonova Coach Station  Economy £86
FlixBus 21h 40m 09:30 Rome Tiburtina Bus Station 07:10 Prague ÚAN Florenc  Economy £86
  • Did you know that if you travel from Rome to Prague via Udine, you can save more than £8? You can find the corresponding connections below.
    • FlixBus
      27h 50m
      0
      17:05
      Rome
      Tiburtina Bus Station
      02:35
      Udine
      Train Station
      0
      FlixBus
      Economy
      £25
      • Waiting Time 8h 15m
    • FlixBus
      10h 5m
      0
      10:50
      Udine
      Train Station
      20:55
      Prague
      ÚAN Florenc
      0
      FlixBus
      Economy
      £35
    Travel time is 7h 10m longer, but you will save £8

Cheapest bus trips Saturday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 28h 15m 18:15 Rome Anagnina Bus Station 21:30 Prague Černý Most  Economy £55
FlixBus 27h 40m 18:15 Rome Anagnina Bus Station 20:55 Prague ÚAN Florenc  Economy £55
FlixBus 20h 40m 17:05 Rome Tiburtina Bus Station 12:45 Prague Wilsonova Coach Station  Economy £71
FlixBus 20h 50m 17:05 Rome Tiburtina Bus Station 12:55 Prague ÚAN Florenc  Economy £71
FlixBus 22h 15m 07:30 Rome Tiburtina Bus Station 04:45 Prague ÚAN Florenc  Economy £72

Best Price Offer: The price for the cheapest coach from Rome to Prague is £55 on 24/10/2026. Flexible travellers save on ticket prices.


Frequency of bus connections between Rome and Prague

See here how frequent the connections between Rome and Prague are, during different times and days of the week.
Friday is the busiest day, with more than 46 daily coaches from Rome to Prague. Sunday has instead the fewest connections, with only 29 daily coaches between Rome and Prague.
The busiest time of the day is the Afternoon, with 133 coaches from Rome to Prague, while Night sees the fewest connections between Rome and Prague, with 5 offers.

Facts about coaches from Rome to Prague

Compare all providers like FlixBus that travel 38 times every day by bus from Rome to Prague in one click! Book your bus ticket from Rome to Prague starting from £55!

Cheapest Bus £55
Fastest Bus 18h 35m
Earliest Coach 10:40
Latest Coach 23:50
Daily Bus Connections 38 Ø
Distance 921.0 km
Coach Companies FlixBus

Cheapest coach connections from Rome to Prague

Every day, 38 buses from 1 coach companies leave Rome for Prague: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 18/10/2026 and for the following days.

Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday
Monday 12/10
Tuesday 13/10
Wednesday 14/10
Thursday 15/10
Friday 16/10
Saturday 17/10
Sunday 18/10
£110
Monday 19/10
£68
Tuesday 20/10
£73
Wednesday 21/10
£67
Thursday 22/10
£70
Friday 23/10
£68
Saturday 24/10
£55
Sunday 25/10
£80
Monday 26/10
£68
Tuesday 27/10
£68
Wednesday 28/10
£67
Thursday 29/10
£79
Friday 30/10
£79
Saturday 31/10
£77
Sunday 01/11
£79
Monday 02/11
£63
Tuesday 03/11
£57
Wednesday 04/11
£60
Thursday 05/11
£64
Friday 06/11
£64
Saturday 07/11
£64
Sunday 08/11

The cheapest time to travel from Rome to Prague

See here on which day and which time of the day you can find the cheapest bus ticket from Rome to Prague, for the next 30 days.
With a price starting from £55, Saturday is the cheapest day for a coach from Rome to Prague. Sunday instead is the most expensive day with prices starting from £68.
Evening is the cheapest day time for bus tickets from Rome to Prague, with £55. Morning is the most expensive time of the day with prices starting from £68.

How to save money travelling from Rome to Prague

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Rome to Prague in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Rome to Prague, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Rome to Prague are also emptier.

All bus stations and stops in Rome and Prague

The map below shows you where to find all the bus stations in Rome and Prague.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Rome to Prague? Compare all modes of transports from Rome to Prague.

Service and Comfort on the bus from Rome to Prague

Want to know which seat classes are available on the coaches from Rome to Prague? Or which bus companies serve the route Rome to Prague? Below you will find answers to your questions.

FAQs about the Rome to Prague bus

How much does a Rome - Prague coach trip cost?

This depends on, among other things, the day and travel time. The cheapest ticket for the Rome - Prague bus trip is available from £55 and takes 27h 15m. Compare offers and save money!

How much could I save by comparing buses from Rome to Prague?

The connection Rome to Prague is offered by 1 companies with ticket prices ranging from £55 to £149. Therefore, we suggest booking your ticket as soon as possible to ensure you will get the cheapest ticket price.

How many connections are available for the Rome - Prague route on average every day?

Each day, the bus route from Rome to Prague is offered by roughly 38 busses. By using our search, you can compare bus schedules and find your ideal trip.

How long does a bus to Prague from Rome take?

The quickest coach from Rome to Prague is provided by FlixBus and takes 18h 35m. Coach tickets for this connection cost £123. However, keep in mind that the connection can take longer due to traffic.

What time is the first bus from Rome to Prague?

The earliest bus to Prague departs from Rome at 10:40. In this context, information about departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

What time is the last coach from Rome to Prague?

The latest bus to Prague departs from Rome at 23:50. Please note that departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

Which bus companies serve the Rome - Prague route?

Passengers looking to travel from Rome to Prague can travel with FlixBus. Compare all available bus tickets with our search to book the trip that works best for you.

Is there a direct bus between Rome and Prague?

You can check all the direct connections between Rome and Prague by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus.

What can I take with me on the bus to Prague from Rome?

Depending on which provider you travel with, what you are allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the bus for the Rome Prague bus route free of charge. Simply use our search to find a coach that is best suited to your needs for your planned travel date.

What equipment is available for the Rome Prague bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make travelling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Rome to Prague on your planned travel date.

How does CheckMyBus find the best bus deals from Rome to Prague?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 38 daily trips between Rome and Prague. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Rome to Prague?

Prices and availability for 38 trips between Rome and Prague change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Rome to Prague

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Rome and to Prague

Here’s an overview of the most popular bus routes to Rome and to Prague. Simply click on the connection of your choice, and you will find all the details about your bus route!
Bus to Rome from Spezzano Albanese Bus to Rome from Spezzano Albanese
Loreto to Rome bus Loreto to Rome bus
Canosa di Puglia to Rome bus Canosa di Puglia to Rome bus
Battipaglia to Rome coach Battipaglia to Rome coach
Bus Jičín to Prague Bus Jičín to Prague
Coach St. Gallen to Prague Coach St. Gallen to Prague
Coach from Dusseldorf to Prague Coach from Dusseldorf to Prague
Bus to Prague from Zadar Bus to Prague from Zadar
Popular Airport Transfers to Rome and to Prague
CheckMyBus › Coaches in Italy › Coach to Rome › Coach to Prague

The CheckMyBus App

Free Download

App Store
CheckMyBus App
Close
GPDR CheckMyBus shield

We value your privacy!

To

show

you

the

best

bus

deals,

we

and

our

partners

use

technical,

analytical,

and

marketing

cookies

for

ads

personalisation.

We

remember

your

anonymized

details

to

provide

a

personalized

experience.