What is the best way to travel from Rome to Prague?
Looking for a trip? Check and compare all the available Buses and Flights to Prague from Rome. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 2 available companies to find your perfect trip!
What is the cheapest way to reach Prague from Rome?
You can reach Prague with just £24 by taking a Flight from Skyscanner, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
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FlixBus26h 45m010:45Rome Ciampino AirportRome Ciampino Airport13:30PragueRoztyly0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 05/12/2025 10:45:00 to Roztyly, Prague (Czech Republic) arriving at 06/12/2025 13:30:00. 50 Economy ticket for £82 per person are available. Travel duration is 26h 45m
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FlixBus20h 30m021:00RomeTiburtina Bus Station17:30PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 05/12/2025 21:00:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 06/12/2025 17:30:00. 50 Economy ticket for £88 per person are available. Travel duration is 20h 30m
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FlixBus24h 50m017:00RomeTiburtina Bus Station17:50PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 05/12/2025 17:00:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 06/12/2025 17:50:00. 50 Economy ticket for £88 per person are available. Travel duration is 24h 50m
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FlixBus20h 45m021:00RomeTiburtina Bus Station17:45PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 05/12/2025 21:00:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 06/12/2025 17:45:00. 50 Economy ticket for £88 per person are available. Travel duration is 20h 45m
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FlixBus24h 20m017:25RomeAnagnina Bus Station17:45PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 05/12/2025 17:25:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 06/12/2025 17:45:00. 50 Economy ticket for £90 per person are available. Travel duration is 24h 20m
Cheapest Buses Friday
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FlixBus20h 30m017:25RomeAnagnina Bus Station13:55PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 06/12/2025 17:25:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 07/12/2025 13:55:00. 50 Economy ticket for £82 per person are available. Travel duration is 20h 30m
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FlixBus20h 40m017:25RomeAnagnina Bus Station14:05PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 06/12/2025 17:25:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 07/12/2025 14:05:00. 50 Economy ticket for £82 per person are available. Travel duration is 20h 40m
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FlixBus22h 30m010:15RomeTiburtina Bus Station08:45PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 06/12/2025 10:15:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 07/12/2025 08:45:00. 50 Economy ticket for £83 per person are available. Travel duration is 22h 30m
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FlixBus23h 50m010:15RomeTiburtina Bus Station10:05PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 06/12/2025 10:15:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 07/12/2025 10:05:00. 50 Economy ticket for £83 per person are available. Travel duration is 23h 50m
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FlixBus22h 0m010:15RomeTiburtina Bus Station08:15PragueRoztyly0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 06/12/2025 10:15:00 to Roztyly, Prague (Czech Republic) arriving at 07/12/2025 08:15:00. 50 Economy ticket for £83 per person are available. Travel duration is 22h 0m
Cheapest Buses Saturday
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Buzz1h 50m008:35Rome Ciampino AirportRome Ciampino Airport10:25Prague AirportPrague Airport - T1/20EconomyA Flight from Buzz goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 07/12/2025 08:35:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 07/12/2025 10:25:00. 50 Economy ticket for £67 per person are available. Travel duration is 1h 50m
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LC Perú2h 0m006:40Rome Fiumicino AirportRome Fiumicino Airport08:40Prague AirportPrague Airport - T1/20EconomyA Flight from LC Perú goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 07/12/2025 06:40:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 07/12/2025 08:40:00. 50 Economy ticket for £72 per person are available. Travel duration is 2h 0m
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Wizz Air10h 50m020:40Rome Fiumicino AirportRome Fiumicino Airport07:30Prague AirportPrague Airport - T1/20EconomyA Flight from Wizz Air goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 07/12/2025 20:40:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 08/12/2025 07:30:00. 50 Economy ticket for £76 per person are available. Travel duration is 10h 50m
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Skyscanner1h 50m016:25Rome Ciampino AirportRome Ciampino Airport18:15Prague AirportPrague Airport - T1/20EconomyA Flight from Skyscanner goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 07/12/2025 16:25:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 07/12/2025 18:15:00. 50 Economy ticket for £91 per person are available. Travel duration is 1h 50m
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Smartwings2h 0m014:00Rome Fiumicino AirportRome Fiumicino Airport16:00Prague AirportPrague Airport - T1/20EconomyA Flight from Smartwings goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 07/12/2025 14:00:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 07/12/2025 16:00:00. 50 Economy ticket for £99 per person are available. Travel duration is 2h 0m
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FlixBus25h 35m001:40RomeTiburtina Bus Station03:15PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 07/12/2025 01:40:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 08/12/2025 03:15:00. 50 Economy ticket for £79 per person are available. Travel duration is 25h 35m
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FlixBus20h 30m009:30RomeTiburtina Bus Station06:00PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 07/12/2025 09:30:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 08/12/2025 06:00:00. 50 Economy ticket for £80 per person are available. Travel duration is 20h 30m
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FlixBus20h 45m009:30RomeTiburtina Bus Station06:15PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 07/12/2025 09:30:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 08/12/2025 06:15:00. 50 Economy ticket for £80 per person are available. Travel duration is 20h 45m
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FlixBus23h 50m010:45Rome Ciampino AirportRome Ciampino Airport10:35PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 07/12/2025 10:45:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 08/12/2025 10:35:00. 50 Economy ticket for £81 per person are available. Travel duration is 23h 50m
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FlixBus20h 30m021:00RomeTiburtina Bus Station17:30PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 07/12/2025 21:00:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 08/12/2025 17:30:00. 50 Economy ticket for £81 per person are available. Travel duration is 20h 30m
Cheapest Flights Sunday
Cheapest Buses Sunday
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Skyscanner1h 50m006:00Rome Ciampino AirportRome Ciampino Airport07:50Prague AirportPrague Airport - T1/20EconomyA Flight from Skyscanner goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 08/12/2025 06:00:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 08/12/2025 07:50:00. 50 Economy ticket for £24 per person are available. Travel duration is 1h 50m
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Buzz1h 50m020:05Rome Ciampino AirportRome Ciampino Airport21:55Prague AirportPrague Airport - T1/20EconomyA Flight from Buzz goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 08/12/2025 20:05:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 08/12/2025 21:55:00. 50 Economy ticket for £34 per person are available. Travel duration is 1h 50m
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LC Perú2h 0m006:40Rome Fiumicino AirportRome Fiumicino Airport08:40Prague AirportPrague Airport - T1/20EconomyA Flight from LC Perú goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 08/12/2025 06:40:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 08/12/2025 08:40:00. 50 Economy ticket for £39 per person are available. Travel duration is 2h 0m
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Smartwings2h 0m014:00Rome Fiumicino AirportRome Fiumicino Airport16:00Prague AirportPrague Airport - T1/20EconomyA Flight from Smartwings goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 08/12/2025 14:00:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 08/12/2025 16:00:00. 50 Economy ticket for £53 per person are available. Travel duration is 2h 0m
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Wizz Air11h 15m021:05Rome Fiumicino AirportRome Fiumicino Airport08:20Prague AirportPrague Airport - T1/20EconomyA Flight from Wizz Air goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 08/12/2025 21:05:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 09/12/2025 08:20:00. 50 Economy ticket for £66 per person are available. Travel duration is 11h 15m
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FlixBus24h 35m017:00RomeTiburtina Bus Station17:35PragueHradčanská0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 08/12/2025 17:00:00 to Hradčanská, Prague (Czech Republic) arriving at 09/12/2025 17:35:00. 50 Economy ticket for £76 per person are available. Travel duration is 24h 35m
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FlixBus20h 45m021:00RomeTiburtina Bus Station17:45PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 08/12/2025 21:00:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 09/12/2025 17:45:00. 50 Economy ticket for £77 per person are available. Travel duration is 20h 45m
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FlixBus20h 30m021:00RomeTiburtina Bus Station17:30PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 08/12/2025 21:00:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 09/12/2025 17:30:00. 50 Economy ticket for £77 per person are available. Travel duration is 20h 30m
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FlixBus27h 0m017:00RomeTiburtina Bus Station20:00PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 08/12/2025 17:00:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 09/12/2025 20:00:00. 50 Economy ticket for £78 per person are available. Travel duration is 27h 0m
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FlixBus24h 30m021:20RomeTiburtina Bus Station21:50PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 08/12/2025 21:20:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 09/12/2025 21:50:00. 50 Economy ticket for £80 per person are available. Travel duration is 24h 30m
Cheapest Flights Monday
Cheapest Buses Monday
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FlixBus25h 55m021:00RomeTiburtina Bus Station22:55PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 09/12/2025 21:00:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 10/12/2025 22:55:00. 50 Economy ticket for £60 per person are available. Travel duration is 25h 55m
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FlixBus24h 45m013:05RomeAnagnina Bus Station13:50PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 09/12/2025 13:05:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 10/12/2025 13:50:00. 50 Economy ticket for £64 per person are available. Travel duration is 24h 45m
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FlixBus24h 35m013:05RomeAnagnina Bus Station13:40PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 09/12/2025 13:05:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 10/12/2025 13:40:00. 50 Economy ticket for £64 per person are available. Travel duration is 24h 35m
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FlixBus27h 0m017:00RomeTiburtina Bus Station20:00PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 09/12/2025 17:00:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 10/12/2025 20:00:00. 50 Economy ticket for £66 per person are available. Travel duration is 27h 0m
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FlixBus20h 30m021:00RomeTiburtina Bus Station17:30PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 09/12/2025 21:00:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 10/12/2025 17:30:00. 50 Economy ticket for £66 per person are available. Travel duration is 20h 30m
Cheapest Buses Tuesday
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Buzz1h 50m019:20Rome Ciampino AirportRome Ciampino Airport21:10Prague AirportPrague Airport - T1/20EconomyA Flight from Buzz goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 10/12/2025 19:20:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 10/12/2025 21:10:00. 50 Economy ticket for £32 per person are available. Travel duration is 1h 50m
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LC Perú12h 20m009:40Rome Fiumicino AirportRome Fiumicino Airport22:00Prague AirportPrague Airport - T1/20EconomyA Flight from LC Perú goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 10/12/2025 09:40:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 10/12/2025 22:00:00. 50 Economy ticket for £71 per person are available. Travel duration is 12h 20m
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Skyscanner5h 20m016:40Rome Ciampino AirportRome Ciampino Airport22:00Prague AirportPrague Airport - T1/20EconomyA Flight from Skyscanner goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 10/12/2025 16:40:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 10/12/2025 22:00:00. 50 Economy ticket for £75 per person are available. Travel duration is 5h 20m
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EasyJet Airline4h 50m010:30Rome Fiumicino AirportRome Fiumicino Airport15:20Prague AirportPrague Airport - T1/20EconomyA Flight from EasyJet Airline goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 10/12/2025 10:30:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 10/12/2025 15:20:00. 50 Economy ticket for £85 per person are available. Travel duration is 4h 50m
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Vueling Airlines14h 40m019:30Rome Fiumicino AirportRome Fiumicino Airport10:10Prague AirportPrague Airport - T1/20EconomyA Flight from Vueling Airlines goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 10/12/2025 19:30:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 11/12/2025 10:10:00. 50 Economy ticket for £113 per person are available. Travel duration is 14h 40m
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RegioJet20h 10m013:00RomeTiburtina Bus Station09:10PragueÚAN Florenc0EconomyA Bus from RegioJet goes from Tiburtina Bus Station, Rome (Italy) at 10/12/2025 13:00:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 11/12/2025 09:10:00. 50 Economy ticket for £49 per person are available. Travel duration is 20h 10m
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FlixBus20h 35m022:55RomeTiburtina Bus Station19:30PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 10/12/2025 22:55:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 11/12/2025 19:30:00. 50 Economy ticket for £64 per person are available. Travel duration is 20h 35m
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FlixBus20h 25m022:55RomeTiburtina Bus Station19:20PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 10/12/2025 22:55:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 11/12/2025 19:20:00. 50 Economy ticket for £64 per person are available. Travel duration is 20h 25m
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FlixBus27h 25m023:50RomeTiburtina Bus Station03:15PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 10/12/2025 23:50:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 12/12/2025 03:15:00. 50 Economy ticket for £64 per person are available. Travel duration is 27h 25m
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RegioJet20h 39m013:00RomeTiburtina Bus Station09:39PragueWilsonova Coach Station0EconomyA Bus from RegioJet goes from Tiburtina Bus Station, Rome (Italy) at 10/12/2025 13:00:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 11/12/2025 09:39:00. 50 Economy ticket for £67 per person are available. Travel duration is 20h 39m
Cheapest Flights Wednesday
Cheapest Buses Wednesday
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FlixBus22h 40m010:45Rome Ciampino AirportRome Ciampino Airport09:25PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 11/12/2025 10:45:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 12/12/2025 09:25:00. 50 Economy ticket for £62 per person are available. Travel duration is 22h 40m
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FlixBus28h 20m017:00RomeTiburtina Bus Station21:20PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 11/12/2025 17:00:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 12/12/2025 21:20:00. 50 Economy ticket for £65 per person are available. Travel duration is 28h 20m
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FlixBus20h 45m009:30RomeTiburtina Bus Station06:15PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 11/12/2025 09:30:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 12/12/2025 06:15:00. 50 Economy ticket for £67 per person are available. Travel duration is 20h 45m
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FlixBus20h 30m009:30RomeTiburtina Bus Station06:00PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 11/12/2025 09:30:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 12/12/2025 06:00:00. 50 Economy ticket for £67 per person are available. Travel duration is 20h 30m
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FlixBus24h 45m012:45RomeAnagnina Bus Station13:30PragueRoztyly0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 11/12/2025 12:45:00 to Roztyly, Prague (Czech Republic) arriving at 12/12/2025 13:30:00. 50 Economy ticket for £68 per person are available. Travel duration is 24h 45m
Cheapest Buses Thursday
What are the fastest trips from Rome to Prague?
You can get to Prague from Rome in just 1h 50m with a Flight from Buzz. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
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FlixBus20h 30m021:00RomeTiburtina Bus Station17:30PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 05/12/2025 21:00:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 06/12/2025 17:30:00. 50 Economy ticket for £88 per person are available. Travel duration is 20h 30m
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FlixBus20h 45m021:00RomeTiburtina Bus Station17:45PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 05/12/2025 21:00:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 06/12/2025 17:45:00. 50 Economy ticket for £88 per person are available. Travel duration is 20h 45m
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FlixBus24h 20m017:25RomeAnagnina Bus Station17:45PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 05/12/2025 17:25:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 06/12/2025 17:45:00. 50 Economy ticket for £90 per person are available. Travel duration is 24h 20m
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FlixBus24h 50m017:00RomeTiburtina Bus Station17:50PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 05/12/2025 17:00:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 06/12/2025 17:50:00. 50 Economy ticket for £88 per person are available. Travel duration is 24h 50m
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FlixBus26h 45m010:45Rome Ciampino AirportRome Ciampino Airport13:30PragueRoztyly0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 05/12/2025 10:45:00 to Roztyly, Prague (Czech Republic) arriving at 06/12/2025 13:30:00. 50 Economy ticket for £82 per person are available. Travel duration is 26h 45m
Fastest Buses Friday
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FlixBus20h 30m017:25RomeAnagnina Bus Station13:55PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 06/12/2025 17:25:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 07/12/2025 13:55:00. 50 Economy ticket for £82 per person are available. Travel duration is 20h 30m
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FlixBus20h 40m017:25RomeAnagnina Bus Station14:05PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 06/12/2025 17:25:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 07/12/2025 14:05:00. 50 Economy ticket for £82 per person are available. Travel duration is 20h 40m
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FlixBus22h 0m010:15RomeTiburtina Bus Station08:15PragueRoztyly0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 06/12/2025 10:15:00 to Roztyly, Prague (Czech Republic) arriving at 07/12/2025 08:15:00. 50 Economy ticket for £83 per person are available. Travel duration is 22h 0m
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FlixBus22h 30m010:15RomeTiburtina Bus Station08:45PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 06/12/2025 10:15:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 07/12/2025 08:45:00. 50 Economy ticket for £83 per person are available. Travel duration is 22h 30m
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FlixBus23h 50m010:15RomeTiburtina Bus Station10:05PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 06/12/2025 10:15:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 07/12/2025 10:05:00. 50 Economy ticket for £83 per person are available. Travel duration is 23h 50m
Fastest Buses Saturday
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Buzz1h 50m008:35Rome Ciampino AirportRome Ciampino Airport10:25Prague AirportPrague Airport - T1/20EconomyA Flight from Buzz goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 07/12/2025 08:35:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 07/12/2025 10:25:00. 50 Economy ticket for £67 per person are available. Travel duration is 1h 50m
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Skyscanner1h 50m016:25Rome Ciampino AirportRome Ciampino Airport18:15Prague AirportPrague Airport - T1/20EconomyA Flight from Skyscanner goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 07/12/2025 16:25:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 07/12/2025 18:15:00. 50 Economy ticket for £91 per person are available. Travel duration is 1h 50m
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LC Perú2h 0m006:40Rome Fiumicino AirportRome Fiumicino Airport08:40Prague AirportPrague Airport - T1/20EconomyA Flight from LC Perú goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 07/12/2025 06:40:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 07/12/2025 08:40:00. 50 Economy ticket for £72 per person are available. Travel duration is 2h 0m
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Smartwings2h 0m014:00Rome Fiumicino AirportRome Fiumicino Airport16:00Prague AirportPrague Airport - T1/20EconomyA Flight from Smartwings goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 07/12/2025 14:00:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 07/12/2025 16:00:00. 50 Economy ticket for £99 per person are available. Travel duration is 2h 0m
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Wizz Air10h 50m020:40Rome Fiumicino AirportRome Fiumicino Airport07:30Prague AirportPrague Airport - T1/20EconomyA Flight from Wizz Air goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 07/12/2025 20:40:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 08/12/2025 07:30:00. 50 Economy ticket for £76 per person are available. Travel duration is 10h 50m
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FlixBus20h 30m009:30RomeTiburtina Bus Station06:00PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 07/12/2025 09:30:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 08/12/2025 06:00:00. 50 Economy ticket for £80 per person are available. Travel duration is 20h 30m
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FlixBus20h 30m021:00RomeTiburtina Bus Station17:30PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 07/12/2025 21:00:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 08/12/2025 17:30:00. 50 Economy ticket for £81 per person are available. Travel duration is 20h 30m
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FlixBus20h 45m009:30RomeTiburtina Bus Station06:15PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 07/12/2025 09:30:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 08/12/2025 06:15:00. 50 Economy ticket for £80 per person are available. Travel duration is 20h 45m
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FlixBus23h 50m010:45Rome Ciampino AirportRome Ciampino Airport10:35PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 07/12/2025 10:45:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 08/12/2025 10:35:00. 50 Economy ticket for £81 per person are available. Travel duration is 23h 50m
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FlixBus25h 35m001:40RomeTiburtina Bus Station03:15PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 07/12/2025 01:40:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 08/12/2025 03:15:00. 50 Economy ticket for £79 per person are available. Travel duration is 25h 35m
Fastest Flights Sunday
Fastest Buses Sunday
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Skyscanner1h 50m006:00Rome Ciampino AirportRome Ciampino Airport07:50Prague AirportPrague Airport - T1/20EconomyA Flight from Skyscanner goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 08/12/2025 06:00:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 08/12/2025 07:50:00. 50 Economy ticket for £24 per person are available. Travel duration is 1h 50m
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Buzz1h 50m020:05Rome Ciampino AirportRome Ciampino Airport21:55Prague AirportPrague Airport - T1/20EconomyA Flight from Buzz goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 08/12/2025 20:05:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 08/12/2025 21:55:00. 50 Economy ticket for £34 per person are available. Travel duration is 1h 50m
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LC Perú2h 0m006:40Rome Fiumicino AirportRome Fiumicino Airport08:40Prague AirportPrague Airport - T1/20EconomyA Flight from LC Perú goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 08/12/2025 06:40:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 08/12/2025 08:40:00. 50 Economy ticket for £39 per person are available. Travel duration is 2h 0m
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Smartwings2h 0m014:00Rome Fiumicino AirportRome Fiumicino Airport16:00Prague AirportPrague Airport - T1/20EconomyA Flight from Smartwings goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 08/12/2025 14:00:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 08/12/2025 16:00:00. 50 Economy ticket for £53 per person are available. Travel duration is 2h 0m
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Wizz Air11h 15m021:05Rome Fiumicino AirportRome Fiumicino Airport08:20Prague AirportPrague Airport - T1/20EconomyA Flight from Wizz Air goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 08/12/2025 21:05:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 09/12/2025 08:20:00. 50 Economy ticket for £66 per person are available. Travel duration is 11h 15m
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FlixBus20h 30m021:00RomeTiburtina Bus Station17:30PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 08/12/2025 21:00:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 09/12/2025 17:30:00. 50 Economy ticket for £77 per person are available. Travel duration is 20h 30m
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FlixBus20h 45m021:00RomeTiburtina Bus Station17:45PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 08/12/2025 21:00:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 09/12/2025 17:45:00. 50 Economy ticket for £77 per person are available. Travel duration is 20h 45m
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FlixBus24h 30m021:20RomeTiburtina Bus Station21:50PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 08/12/2025 21:20:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 09/12/2025 21:50:00. 50 Economy ticket for £80 per person are available. Travel duration is 24h 30m
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FlixBus24h 35m017:00RomeTiburtina Bus Station17:35PragueHradčanská0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 08/12/2025 17:00:00 to Hradčanská, Prague (Czech Republic) arriving at 09/12/2025 17:35:00. 50 Economy ticket for £76 per person are available. Travel duration is 24h 35m
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FlixBus27h 0m017:00RomeTiburtina Bus Station20:00PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 08/12/2025 17:00:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 09/12/2025 20:00:00. 50 Economy ticket for £78 per person are available. Travel duration is 27h 0m
Fastest Flights Monday
Fastest Buses Monday
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FlixBus20h 30m021:00RomeTiburtina Bus Station17:30PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 09/12/2025 21:00:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 10/12/2025 17:30:00. 50 Economy ticket for £66 per person are available. Travel duration is 20h 30m
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FlixBus24h 35m013:05RomeAnagnina Bus Station13:40PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 09/12/2025 13:05:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 10/12/2025 13:40:00. 50 Economy ticket for £64 per person are available. Travel duration is 24h 35m
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FlixBus24h 45m013:05RomeAnagnina Bus Station13:50PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 09/12/2025 13:05:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 10/12/2025 13:50:00. 50 Economy ticket for £64 per person are available. Travel duration is 24h 45m
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FlixBus25h 55m021:00RomeTiburtina Bus Station22:55PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 09/12/2025 21:00:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 10/12/2025 22:55:00. 50 Economy ticket for £60 per person are available. Travel duration is 25h 55m
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FlixBus27h 0m017:00RomeTiburtina Bus Station20:00PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 09/12/2025 17:00:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 10/12/2025 20:00:00. 50 Economy ticket for £66 per person are available. Travel duration is 27h 0m
Fastest Buses Tuesday
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Buzz1h 50m019:20Rome Ciampino AirportRome Ciampino Airport21:10Prague AirportPrague Airport - T1/20EconomyA Flight from Buzz goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 10/12/2025 19:20:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 10/12/2025 21:10:00. 50 Economy ticket for £32 per person are available. Travel duration is 1h 50m
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EasyJet Airline4h 50m010:30Rome Fiumicino AirportRome Fiumicino Airport15:20Prague AirportPrague Airport - T1/20EconomyA Flight from EasyJet Airline goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 10/12/2025 10:30:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 10/12/2025 15:20:00. 50 Economy ticket for £85 per person are available. Travel duration is 4h 50m
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Skyscanner5h 20m016:40Rome Ciampino AirportRome Ciampino Airport22:00Prague AirportPrague Airport - T1/20EconomyA Flight from Skyscanner goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 10/12/2025 16:40:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 10/12/2025 22:00:00. 50 Economy ticket for £75 per person are available. Travel duration is 5h 20m
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LC Perú12h 20m009:40Rome Fiumicino AirportRome Fiumicino Airport22:00Prague AirportPrague Airport - T1/20EconomyA Flight from LC Perú goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 10/12/2025 09:40:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 10/12/2025 22:00:00. 50 Economy ticket for £71 per person are available. Travel duration is 12h 20m
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Vueling Airlines14h 40m019:30Rome Fiumicino AirportRome Fiumicino Airport10:10Prague AirportPrague Airport - T1/20EconomyA Flight from Vueling Airlines goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 10/12/2025 19:30:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 11/12/2025 10:10:00. 50 Economy ticket for £113 per person are available. Travel duration is 14h 40m
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RegioJet20h 10m013:00RomeTiburtina Bus Station09:10PragueÚAN Florenc0EconomyA Bus from RegioJet goes from Tiburtina Bus Station, Rome (Italy) at 10/12/2025 13:00:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 11/12/2025 09:10:00. 50 Economy ticket for £49 per person are available. Travel duration is 20h 10m
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FlixBus20h 25m022:55RomeTiburtina Bus Station19:20PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 10/12/2025 22:55:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 11/12/2025 19:20:00. 50 Economy ticket for £64 per person are available. Travel duration is 20h 25m
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FlixBus20h 35m022:55RomeTiburtina Bus Station19:30PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 10/12/2025 22:55:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 11/12/2025 19:30:00. 50 Economy ticket for £64 per person are available. Travel duration is 20h 35m
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RegioJet20h 39m013:00RomeTiburtina Bus Station09:39PragueWilsonova Coach Station0EconomyA Bus from RegioJet goes from Tiburtina Bus Station, Rome (Italy) at 10/12/2025 13:00:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 11/12/2025 09:39:00. 50 Economy ticket for £67 per person are available. Travel duration is 20h 39m
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FlixBus27h 25m023:50RomeTiburtina Bus Station03:15PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 10/12/2025 23:50:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 12/12/2025 03:15:00. 50 Economy ticket for £64 per person are available. Travel duration is 27h 25m
Fastest Flights Wednesday
Fastest Buses Wednesday
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FlixBus20h 30m009:30RomeTiburtina Bus Station06:00PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 11/12/2025 09:30:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 12/12/2025 06:00:00. 50 Economy ticket for £67 per person are available. Travel duration is 20h 30m
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FlixBus20h 45m009:30RomeTiburtina Bus Station06:15PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 11/12/2025 09:30:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 12/12/2025 06:15:00. 50 Economy ticket for £67 per person are available. Travel duration is 20h 45m
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FlixBus22h 40m010:45Rome Ciampino AirportRome Ciampino Airport09:25PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 11/12/2025 10:45:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 12/12/2025 09:25:00. 50 Economy ticket for £62 per person are available. Travel duration is 22h 40m
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FlixBus24h 45m012:45RomeAnagnina Bus Station13:30PragueRoztyly0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 11/12/2025 12:45:00 to Roztyly, Prague (Czech Republic) arriving at 12/12/2025 13:30:00. 50 Economy ticket for £68 per person are available. Travel duration is 24h 45m
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FlixBus28h 20m017:00RomeTiburtina Bus Station21:20PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 11/12/2025 17:00:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 12/12/2025 21:20:00. 50 Economy ticket for £65 per person are available. Travel duration is 28h 20m
Fastest Buses Thursday
Here you will find all operators and timetables for a
Bus from Rome to Prague
What are the most popular stations in Rome and Prague?
In Rome, you will usually depart from Termini Bus Station, Termini Central Station or Ostiense Train Station, while in Prague you will be arriving at Wilsonova Coach Station, ÚAN Florenc or Černý Most, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Prague from Rome? With 7 connections between 2 Bus and Flight operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Rome and Prague, you can pay as low as £24 with a Flight from Skyscanner.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Buzz: you will get to Prague in just 1h 50m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Rome and Prague are FlixBus, Buzz and LC Perú, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Rome and Prague is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Settebagni or to Horoměřice, and look at flights from Rome Ciampino Airport, and landing at Prague Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Rome to Prague?
The most popular companies between Rome and Prague, are FlixBus, Buzz and LC Perú. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: FlixBus and RegioJet
Airlines: Buzz, LC Perú, Skyscanner and 4 more.
All you need to know when you travel from Rome to Prague
Check all information on comfort and services on all modes of transports from Rome to Prague. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Rome to Prague
How can I reach Prague from Rome?
Every day, there are on average 7 connections between Bus and Flight, with which you can get to Prague from Rome.
How far is Prague from Rome?
The distance between Rome and Prague is 921.0 km.
What is the most ecofriendly mode of transport between Rome and Prague?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 25 kgs of CO2, a train 32 kgs, a car 157 kgs, and a flight 227 kgs.
What is the cheapest mode of transport from Rome to Prague?
You can get to Prague with just £24 by taking a Flight from Skyscanner.
What is the fastest way to get from Rome to Prague?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Prague in just 1h 50m with a Flight from Buzz.
More routes to Rome and to Prague
Looking for more options? Here you can see the most popular routes to Rome and to Prague. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Rome
- Avellino to Rome
- Bari to Rome
- Battipaglia to Rome
- Caserta to Rome
- Catanzaro to Rome
- Chieti to Rome
- Civitanova to Rome
- Foggia to Rome
- Genoa to Rome
- L'Aquila to Rome
- Lamezia Terme to Rome
- Lecce to Rome
- Milan to Rome
- Mosciano Sant'Angelo to Rome
- Naples to Rome
- Palermo to Rome
- Perugia to Rome
- Pescara to Rome
- Potenza to Rome
- Rome Fiumicino Airport to Rome
- Sala Consilina to Rome
- Salerno to Rome
- San Benedetto del Tronto to Rome
- Venice to Rome
- Trips to Prague
- Amsterdam to Prague
- Bern to Prague
- Bologna to Prague
- Bratislava to Prague
- Břeclav to Prague
- Brno to Prague
- Chemnitz to Prague
- Dortmund to Prague
- Hamburg to Prague
- Humpolec to Prague
- Istanbul to Prague
- Katowice to Prague
- Kosice to Prague
- Memmingen to Prague
- Nuremberg to Prague
- Ostrava to Prague
- Paris to Prague
- Pilsen to Prague
- Prague Airport to Prague
- Presov to Prague
- Teplice to Prague
- Třebíč to Prague
- Warsaw to Prague
- Wroclaw to Prague

