What is the best way to travel from Rome to Prague?
Looking for a trip? Check and compare all the available Buses and Flights to Prague from Rome. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 1 available companies to find your perfect trip!
What is the cheapest way to reach Prague from Rome?
You can reach Prague with just £21 by taking a Flight from Ryanair, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
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LC Perú11h 35m019:40Rome Fiumicino AirportRome Fiumicino Airport07:15Prague AirportPrague Airport - T1/20EconomyA Flight from LC Perú goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 14/04/2026 19:40:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 15/04/2026 07:15:00. 50 Economy ticket for £60 per person are available. Travel duration is 11h 35m
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Buzz10h 10m021:05Rome Ciampino AirportRome Ciampino Airport07:15Prague AirportPrague Airport - T1/20EconomyA Flight from Buzz goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 14/04/2026 21:05:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 15/04/2026 07:15:00. 50 Economy ticket for £69 per person are available. Travel duration is 10h 10m
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AJet22h 30m012:30Rome Fiumicino AirportRome Fiumicino Airport11:00Prague AirportPrague Airport0EconomyA Flight from AJet goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 14/04/2026 12:30:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 15/04/2026 11:00:00. 50 Economy ticket for £124 per person are available. Travel duration is 22h 30m
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Pegasus Group LTD20h 10m014:50Rome Fiumicino AirportRome Fiumicino Airport11:00Prague AirportPrague Airport0EconomyA Flight from Pegasus Group LTD goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 14/04/2026 14:50:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 15/04/2026 11:00:00. 50 Economy ticket for £127 per person are available. Travel duration is 20h 10m
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Wizz Air20h 25m018:35Rome Fiumicino AirportRome Fiumicino Airport15:00Prague AirportPrague Airport0EconomyA Flight from Wizz Air goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 14/04/2026 18:35:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 15/04/2026 15:00:00. 50 Economy ticket for £146 per person are available. Travel duration is 20h 25m
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FlixBus27h 5m013:05RomeAnagnina Bus Station16:10PragueČerný Most0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 14/04/2026 13:05:00 to Černý Most, Prague (Czech Republic) arriving at 15/04/2026 16:10:00. 50 Economy ticket for £63 per person are available. Travel duration is 27h 5m
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FlixBus24h 50m010:40RomeTiburtina Bus Station11:30PragueZličín0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 14/04/2026 10:40:00 to Zličín, Prague (Czech Republic) arriving at 15/04/2026 11:30:00. 50 Economy ticket for £66 per person are available. Travel duration is 24h 50m
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FlixBus30h 0m015:30Rome Ciampino AirportRome Ciampino Airport21:30PragueČerný Most0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 14/04/2026 15:30:00 to Černý Most, Prague (Czech Republic) arriving at 15/04/2026 21:30:00. 50 Economy ticket for £69 per person are available. Travel duration is 30h 0m
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FlixBus29h 25m015:30Rome Ciampino AirportRome Ciampino Airport20:55PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 14/04/2026 15:30:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 15/04/2026 20:55:00. 50 Economy ticket for £69 per person are available. Travel duration is 29h 25m
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FlixBus30h 50m010:45Rome Ciampino AirportRome Ciampino Airport17:35PragueHradčanská0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 14/04/2026 10:45:00 to Hradčanská, Prague (Czech Republic) arriving at 15/04/2026 17:35:00. 50 Economy ticket for £71 per person are available. Travel duration is 30h 50m
Cheapest Flights Tuesday
Cheapest Buses Tuesday
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Ryanair1h 50m006:00Rome Ciampino AirportRome Ciampino Airport07:50Prague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 15/04/2026 06:00:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 15/04/2026 07:50:00. 50 Economy ticket for £21 per person are available. Travel duration is 1h 50m
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Skyscanner1h 50m006:00Rome Ciampino AirportRome Ciampino Airport07:50Prague AirportPrague Airport - T1/20EconomyA Flight from Skyscanner goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 15/04/2026 06:00:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 15/04/2026 07:50:00. 50 Economy ticket for £22 per person are available. Travel duration is 1h 50m
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LC Perú1h 55m006:45Rome Fiumicino AirportRome Fiumicino Airport08:40Prague AirportPrague Airport - T1/20EconomyA Flight from LC Perú goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 15/04/2026 06:45:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 15/04/2026 08:40:00. 50 Economy ticket for £25 per person are available. Travel duration is 1h 55m
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Wizz Air1h 55m006:45Rome Fiumicino AirportRome Fiumicino Airport08:40Prague AirportPrague Airport - T1/20EconomyA Flight from Wizz Air goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 15/04/2026 06:45:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 15/04/2026 08:40:00. 50 Economy ticket for £29 per person are available. Travel duration is 1h 55m
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Smartwings2h 0m014:00Rome Fiumicino AirportRome Fiumicino Airport16:00Prague AirportPrague Airport - T1/20EconomyA Flight from Smartwings goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 15/04/2026 14:00:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 15/04/2026 16:00:00. 50 Economy ticket for £63 per person are available. Travel duration is 2h 0m
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FlixBus27h 40m023:35RomeAnagnina Bus Station03:15PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 15/04/2026 23:35:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 17/04/2026 03:15:00. 50 Economy ticket for £66 per person are available. Travel duration is 27h 40m
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FlixBus25h 25m010:45Rome Ciampino AirportRome Ciampino Airport12:10PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 15/04/2026 10:45:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 16/04/2026 12:10:00. 50 Economy ticket for £67 per person are available. Travel duration is 25h 25m
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FlixBus26h 55m021:00RomeTiburtina Bus Station23:55PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 15/04/2026 21:00:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 16/04/2026 23:55:00. 50 Economy ticket for £67 per person are available. Travel duration is 26h 55m
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FlixBus20h 30m021:00RomeTiburtina Bus Station17:30PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 15/04/2026 21:00:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 16/04/2026 17:30:00. 50 Economy ticket for £67 per person are available. Travel duration is 20h 30m
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FlixBus23h 20m021:00RomeTiburtina Bus Station20:20PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 15/04/2026 21:00:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 16/04/2026 20:20:00. 50 Economy ticket for £67 per person are available. Travel duration is 23h 20m
Cheapest Flights Wednesday
Cheapest Buses Wednesday
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Skyscanner1h 50m006:00Rome Ciampino AirportRome Ciampino Airport07:50Prague AirportPrague Airport - T1/20EconomyA Flight from Skyscanner goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 16/04/2026 06:00:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 16/04/2026 07:50:00. 50 Economy ticket for £24 per person are available. Travel duration is 1h 50m
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Ryanair1h 50m006:00Rome Ciampino AirportRome Ciampino Airport07:50Prague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 16/04/2026 06:00:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 16/04/2026 07:50:00. 50 Economy ticket for £24 per person are available. Travel duration is 1h 50m
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Wizz Air1h 55m006:45Rome Fiumicino AirportRome Fiumicino Airport08:40Prague AirportPrague Airport - T1/20EconomyA Flight from Wizz Air goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 16/04/2026 06:45:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 16/04/2026 08:40:00. 50 Economy ticket for £24 per person are available. Travel duration is 1h 55m
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LC Perú1h 55m006:45Rome Fiumicino AirportRome Fiumicino Airport08:40Prague AirportPrague Airport - T1/20EconomyA Flight from LC Perú goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 16/04/2026 06:45:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 16/04/2026 08:40:00. 50 Economy ticket for £27 per person are available. Travel duration is 1h 55m
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Smartwings2h 0m014:00Rome Fiumicino AirportRome Fiumicino Airport16:00Prague AirportPrague Airport - T1/20EconomyA Flight from Smartwings goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 16/04/2026 14:00:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 16/04/2026 16:00:00. 50 Economy ticket for £62 per person are available. Travel duration is 2h 0m
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FlixBus27h 40m023:35RomeAnagnina Bus Station03:15PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 16/04/2026 23:35:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 18/04/2026 03:15:00. 50 Economy ticket for £67 per person are available. Travel duration is 27h 40m
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FlixBus22h 40m010:45Rome Ciampino AirportRome Ciampino Airport09:25PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 16/04/2026 10:45:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 17/04/2026 09:25:00. 50 Economy ticket for £68 per person are available. Travel duration is 22h 40m
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FlixBus27h 55m022:55RomeTiburtina Bus Station02:50PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 16/04/2026 22:55:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 18/04/2026 02:50:00. 50 Economy ticket for £69 per person are available. Travel duration is 27h 55m
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FlixBus24h 0m022:55RomeTiburtina Bus Station22:55PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 16/04/2026 22:55:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 17/04/2026 22:55:00. 50 Economy ticket for £69 per person are available. Travel duration is 24h 0m
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FlixBus20h 50m017:05RomeTiburtina Bus Station13:55PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 16/04/2026 17:05:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 17/04/2026 13:55:00. 50 Economy ticket for £70 per person are available. Travel duration is 20h 50m
Cheapest Flights Thursday
Cheapest Buses Thursday
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Ryanair1h 50m009:45Rome Ciampino AirportRome Ciampino Airport11:35Prague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 17/04/2026 09:45:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 17/04/2026 11:35:00. 50 Economy ticket for £52 per person are available. Travel duration is 1h 50m
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Skyscanner1h 50m009:45Rome Ciampino AirportRome Ciampino Airport11:35Prague AirportPrague Airport - T1/20EconomyA Flight from Skyscanner goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 17/04/2026 09:45:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 17/04/2026 11:35:00. 50 Economy ticket for £53 per person are available. Travel duration is 1h 50m
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Wizz Air5h 5m008:45Rome Fiumicino AirportRome Fiumicino Airport13:50Prague AirportPrague Airport - T1/20EconomyA Flight from Wizz Air goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 17/04/2026 08:45:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 17/04/2026 13:50:00. 50 Economy ticket for £58 per person are available. Travel duration is 5h 5m
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Buzz12h 15m018:35Rome Ciampino AirportRome Ciampino Airport06:50Prague AirportPrague Airport - T1/20EconomyA Flight from Buzz goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 17/04/2026 18:35:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 18/04/2026 06:50:00. 50 Economy ticket for £62 per person are available. Travel duration is 12h 15m
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LC Perú1h 55m006:45Rome Fiumicino AirportRome Fiumicino Airport08:40Prague AirportPrague Airport - T1/20EconomyA Flight from LC Perú goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 17/04/2026 06:45:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 17/04/2026 08:40:00. 50 Economy ticket for £63 per person are available. Travel duration is 1h 55m
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FlixBus27h 40m023:35RomeAnagnina Bus Station03:15PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 17/04/2026 23:35:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 19/04/2026 03:15:00. 50 Economy ticket for £70 per person are available. Travel duration is 27h 40m
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FlixBus26h 55m021:00RomeTiburtina Bus Station23:55PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 17/04/2026 21:00:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 18/04/2026 23:55:00. 50 Economy ticket for £72 per person are available. Travel duration is 26h 55m
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FlixBus24h 20m017:25RomeAnagnina Bus Station17:45PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 17/04/2026 17:25:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 18/04/2026 17:45:00. 50 Economy ticket for £72 per person are available. Travel duration is 24h 20m
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FlixBus23h 50m010:45Rome Ciampino AirportRome Ciampino Airport10:35PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 17/04/2026 10:45:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 18/04/2026 10:35:00. 50 Economy ticket for £73 per person are available. Travel duration is 23h 50m
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FlixBus25h 35m001:40RomeTiburtina Bus Station03:15PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 17/04/2026 01:40:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 18/04/2026 03:15:00. 50 Economy ticket for £73 per person are available. Travel duration is 25h 35m
Cheapest Flights Friday
Cheapest Buses Friday
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Skyscanner9h 50m022:25Rome Fiumicino AirportRome Fiumicino Airport08:15Prague AirportPrague Airport - T1/20EconomyA Flight from Skyscanner goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 18/04/2026 22:25:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 19/04/2026 08:15:00. 50 Economy ticket for £51 per person are available. Travel duration is 9h 50m
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LC Perú1h 55m006:45Rome Fiumicino AirportRome Fiumicino Airport08:40Prague AirportPrague Airport - T1/20EconomyA Flight from LC Perú goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 18/04/2026 06:45:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 18/04/2026 08:40:00. 50 Economy ticket for £54 per person are available. Travel duration is 1h 55m
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Smartwings2h 0m014:00Rome Fiumicino AirportRome Fiumicino Airport16:00Prague AirportPrague Airport - T1/20EconomyA Flight from Smartwings goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 18/04/2026 14:00:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 18/04/2026 16:00:00. 50 Economy ticket for £62 per person are available. Travel duration is 2h 0m
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Ryanair22h 15m008:30Rome Ciampino AirportRome Ciampino Airport06:45Prague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 18/04/2026 08:30:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 19/04/2026 06:45:00. 50 Economy ticket for £72 per person are available. Travel duration is 22h 15m
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Buzz7h 30m009:45Rome Fiumicino AirportRome Fiumicino Airport17:15Prague AirportPrague Airport - T1/20EconomyA Flight from Buzz goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 18/04/2026 09:45:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 18/04/2026 17:15:00. 50 Economy ticket for £85 per person are available. Travel duration is 7h 30m
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FlixBus30h 0m015:30Rome Ciampino AirportRome Ciampino Airport21:30PragueČerný Most0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 18/04/2026 15:30:00 to Černý Most, Prague (Czech Republic) arriving at 19/04/2026 21:30:00. 50 Economy ticket for £60 per person are available. Travel duration is 30h 0m
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FlixBus29h 25m015:30Rome Ciampino AirportRome Ciampino Airport20:55PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 18/04/2026 15:30:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 19/04/2026 20:55:00. 50 Economy ticket for £60 per person are available. Travel duration is 29h 25m
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FlixBus27h 40m023:35RomeAnagnina Bus Station03:15PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 18/04/2026 23:35:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 20/04/2026 03:15:00. 50 Economy ticket for £65 per person are available. Travel duration is 27h 40m
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FlixBus22h 40m010:45Rome Ciampino AirportRome Ciampino Airport09:25PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 18/04/2026 10:45:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 19/04/2026 09:25:00. 50 Economy ticket for £66 per person are available. Travel duration is 22h 40m
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FlixBus23h 50m010:45Rome Ciampino AirportRome Ciampino Airport10:35PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 18/04/2026 10:45:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 19/04/2026 10:35:00. 50 Economy ticket for £69 per person are available. Travel duration is 23h 50m
Cheapest Flights Saturday
Cheapest Buses Saturday
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Wizz Air1h 55m006:45Rome Fiumicino AirportRome Fiumicino Airport08:40Prague AirportPrague Airport - T1/20EconomyA Flight from Wizz Air goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 19/04/2026 06:45:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 19/04/2026 08:40:00. 50 Economy ticket for £43 per person are available. Travel duration is 1h 55m
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Ryanair26h 40m007:40Rome Ciampino AirportRome Ciampino Airport10:20Prague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 19/04/2026 07:40:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 20/04/2026 10:20:00. 50 Economy ticket for £64 per person are available. Travel duration is 26h 40m
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Air Serbia11h 40m021:00Rome Fiumicino AirportRome Fiumicino Airport08:40Prague AirportPrague Airport0EconomyA Flight from Air Serbia goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 19/04/2026 21:00:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 20/04/2026 08:40:00. 50 Economy ticket for £114 per person are available. Travel duration is 11h 40m
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ITA Airways8h 15m009:15Rome Fiumicino AirportRome Fiumicino Airport17:30Prague AirportPrague Airport0EconomyA Flight from ITA Airways goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 19/04/2026 09:15:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 19/04/2026 17:30:00. 50 Economy ticket for £117 per person are available. Travel duration is 8h 15m
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EasyJet Airline23h 45m010:40Rome Fiumicino AirportRome Fiumicino Airport10:25Prague AirportPrague Airport0EconomyA Flight from EasyJet Airline goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 19/04/2026 10:40:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 20/04/2026 10:25:00. 50 Economy ticket for £161 per person are available. Travel duration is 23h 45m
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FlixBus27h 40m023:35RomeAnagnina Bus Station03:15PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 19/04/2026 23:35:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 21/04/2026 03:15:00. 50 Economy ticket for £63 per person are available. Travel duration is 27h 40m
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FlixBus26h 55m021:00RomeTiburtina Bus Station23:55PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 19/04/2026 21:00:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 20/04/2026 23:55:00. 50 Economy ticket for £66 per person are available. Travel duration is 26h 55m
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FlixBus20h 30m021:00RomeTiburtina Bus Station17:30PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 19/04/2026 21:00:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 20/04/2026 17:30:00. 50 Economy ticket for £67 per person are available. Travel duration is 20h 30m
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FlixBus20h 45m021:00RomeTiburtina Bus Station17:45PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 19/04/2026 21:00:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 20/04/2026 17:45:00. 50 Economy ticket for £67 per person are available. Travel duration is 20h 45m
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FlixBus23h 20m021:00RomeTiburtina Bus Station20:20PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 19/04/2026 21:00:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 20/04/2026 20:20:00. 50 Economy ticket for £67 per person are available. Travel duration is 23h 20m
Cheapest Flights Sunday
Cheapest Buses Sunday
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LC Perú1h 55m006:45Rome Fiumicino AirportRome Fiumicino Airport08:40Prague AirportPrague Airport - T1/20EconomyA Flight from LC Perú goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 20/04/2026 06:45:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 20/04/2026 08:40:00. 50 Economy ticket for £43 per person are available. Travel duration is 1h 55m
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Ryanair9h 50m007:40Rome Ciampino AirportRome Ciampino Airport17:30Prague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 20/04/2026 07:40:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 20/04/2026 17:30:00. 50 Economy ticket for £58 per person are available. Travel duration is 9h 50m
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Skyscanner8h 30m006:05Rome Fiumicino AirportRome Fiumicino Airport14:35Prague AirportPrague Airport - T1/20EconomyA Flight from Skyscanner goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 20/04/2026 06:05:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 20/04/2026 14:35:00. 50 Economy ticket for £62 per person are available. Travel duration is 8h 30m
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Wizz Air6h 5m008:35Rome Fiumicino AirportRome Fiumicino Airport14:40Prague AirportPrague Airport - T1/20EconomyA Flight from Wizz Air goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 20/04/2026 08:35:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 20/04/2026 14:40:00. 50 Economy ticket for £69 per person are available. Travel duration is 6h 5m
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Smartwings2h 0m014:00Rome Fiumicino AirportRome Fiumicino Airport16:00Prague AirportPrague Airport - T1/20EconomyA Flight from Smartwings goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 20/04/2026 14:00:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 20/04/2026 16:00:00. 50 Economy ticket for £75 per person are available. Travel duration is 2h 0m
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FlixBus30h 0m015:30Rome Ciampino AirportRome Ciampino Airport21:30PragueČerný Most0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 20/04/2026 15:30:00 to Černý Most, Prague (Czech Republic) arriving at 21/04/2026 21:30:00. 50 Economy ticket for £53 per person are available. Travel duration is 30h 0m
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FlixBus29h 25m015:30Rome Ciampino AirportRome Ciampino Airport20:55PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 20/04/2026 15:30:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 21/04/2026 20:55:00. 50 Economy ticket for £53 per person are available. Travel duration is 29h 25m
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FlixBus21h 40m009:30RomeTiburtina Bus Station07:10PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 20/04/2026 09:30:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 21/04/2026 07:10:00. 50 Economy ticket for £58 per person are available. Travel duration is 21h 40m
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FlixBus21h 30m009:30RomeTiburtina Bus Station07:00PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 20/04/2026 09:30:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 21/04/2026 07:00:00. 50 Economy ticket for £58 per person are available. Travel duration is 21h 30m
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FlixBus24h 25m013:05RomeAnagnina Bus Station13:30PragueRoztyly0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 20/04/2026 13:05:00 to Roztyly, Prague (Czech Republic) arriving at 21/04/2026 13:30:00. 50 Economy ticket for £58 per person are available. Travel duration is 24h 25m
Cheapest Flights Monday
Cheapest Buses Monday
What are the fastest trips from Rome to Prague?
You can get to Prague from Rome in just 1h 50m with a Flight from Ryanair. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
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Buzz10h 10m021:05Rome Ciampino AirportRome Ciampino Airport07:15Prague AirportPrague Airport - T1/20EconomyA Flight from Buzz goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 14/04/2026 21:05:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 15/04/2026 07:15:00. 50 Economy ticket for £69 per person are available. Travel duration is 10h 10m
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LC Perú11h 35m019:40Rome Fiumicino AirportRome Fiumicino Airport07:15Prague AirportPrague Airport - T1/20EconomyA Flight from LC Perú goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 14/04/2026 19:40:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 15/04/2026 07:15:00. 50 Economy ticket for £60 per person are available. Travel duration is 11h 35m
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Pegasus Group LTD20h 10m014:50Rome Fiumicino AirportRome Fiumicino Airport11:00Prague AirportPrague Airport0EconomyA Flight from Pegasus Group LTD goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 14/04/2026 14:50:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 15/04/2026 11:00:00. 50 Economy ticket for £127 per person are available. Travel duration is 20h 10m
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Wizz Air20h 25m018:35Rome Fiumicino AirportRome Fiumicino Airport15:00Prague AirportPrague Airport0EconomyA Flight from Wizz Air goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 14/04/2026 18:35:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 15/04/2026 15:00:00. 50 Economy ticket for £146 per person are available. Travel duration is 20h 25m
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AJet22h 30m012:30Rome Fiumicino AirportRome Fiumicino Airport11:00Prague AirportPrague Airport0EconomyA Flight from AJet goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 14/04/2026 12:30:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 15/04/2026 11:00:00. 50 Economy ticket for £124 per person are available. Travel duration is 22h 30m
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FlixBus24h 50m010:40RomeTiburtina Bus Station11:30PragueZličín0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 14/04/2026 10:40:00 to Zličín, Prague (Czech Republic) arriving at 15/04/2026 11:30:00. 50 Economy ticket for £66 per person are available. Travel duration is 24h 50m
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FlixBus27h 5m013:05RomeAnagnina Bus Station16:10PragueČerný Most0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 14/04/2026 13:05:00 to Černý Most, Prague (Czech Republic) arriving at 15/04/2026 16:10:00. 50 Economy ticket for £63 per person are available. Travel duration is 27h 5m
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FlixBus29h 25m015:30Rome Ciampino AirportRome Ciampino Airport20:55PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 14/04/2026 15:30:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 15/04/2026 20:55:00. 50 Economy ticket for £69 per person are available. Travel duration is 29h 25m
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FlixBus30h 0m015:30Rome Ciampino AirportRome Ciampino Airport21:30PragueČerný Most0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 14/04/2026 15:30:00 to Černý Most, Prague (Czech Republic) arriving at 15/04/2026 21:30:00. 50 Economy ticket for £69 per person are available. Travel duration is 30h 0m
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FlixBus30h 50m010:45Rome Ciampino AirportRome Ciampino Airport17:35PragueHradčanská0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 14/04/2026 10:45:00 to Hradčanská, Prague (Czech Republic) arriving at 15/04/2026 17:35:00. 50 Economy ticket for £71 per person are available. Travel duration is 30h 50m
Fastest Flights Tuesday
Fastest Buses Tuesday
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Ryanair1h 50m006:00Rome Ciampino AirportRome Ciampino Airport07:50Prague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 15/04/2026 06:00:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 15/04/2026 07:50:00. 50 Economy ticket for £21 per person are available. Travel duration is 1h 50m
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Skyscanner1h 50m006:00Rome Ciampino AirportRome Ciampino Airport07:50Prague AirportPrague Airport - T1/20EconomyA Flight from Skyscanner goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 15/04/2026 06:00:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 15/04/2026 07:50:00. 50 Economy ticket for £22 per person are available. Travel duration is 1h 50m
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LC Perú1h 55m006:45Rome Fiumicino AirportRome Fiumicino Airport08:40Prague AirportPrague Airport - T1/20EconomyA Flight from LC Perú goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 15/04/2026 06:45:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 15/04/2026 08:40:00. 50 Economy ticket for £25 per person are available. Travel duration is 1h 55m
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Wizz Air1h 55m006:45Rome Fiumicino AirportRome Fiumicino Airport08:40Prague AirportPrague Airport - T1/20EconomyA Flight from Wizz Air goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 15/04/2026 06:45:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 15/04/2026 08:40:00. 50 Economy ticket for £29 per person are available. Travel duration is 1h 55m
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Smartwings2h 0m014:00Rome Fiumicino AirportRome Fiumicino Airport16:00Prague AirportPrague Airport - T1/20EconomyA Flight from Smartwings goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 15/04/2026 14:00:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 15/04/2026 16:00:00. 50 Economy ticket for £63 per person are available. Travel duration is 2h 0m
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FlixBus20h 30m021:00RomeTiburtina Bus Station17:30PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 15/04/2026 21:00:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 16/04/2026 17:30:00. 50 Economy ticket for £67 per person are available. Travel duration is 20h 30m
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FlixBus23h 20m021:00RomeTiburtina Bus Station20:20PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 15/04/2026 21:00:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 16/04/2026 20:20:00. 50 Economy ticket for £67 per person are available. Travel duration is 23h 20m
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FlixBus25h 25m010:45Rome Ciampino AirportRome Ciampino Airport12:10PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 15/04/2026 10:45:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 16/04/2026 12:10:00. 50 Economy ticket for £67 per person are available. Travel duration is 25h 25m
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FlixBus26h 55m021:00RomeTiburtina Bus Station23:55PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 15/04/2026 21:00:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 16/04/2026 23:55:00. 50 Economy ticket for £67 per person are available. Travel duration is 26h 55m
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FlixBus27h 40m023:35RomeAnagnina Bus Station03:15PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 15/04/2026 23:35:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 17/04/2026 03:15:00. 50 Economy ticket for £66 per person are available. Travel duration is 27h 40m
Fastest Flights Wednesday
Fastest Buses Wednesday
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Skyscanner1h 50m006:00Rome Ciampino AirportRome Ciampino Airport07:50Prague AirportPrague Airport - T1/20EconomyA Flight from Skyscanner goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 16/04/2026 06:00:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 16/04/2026 07:50:00. 50 Economy ticket for £24 per person are available. Travel duration is 1h 50m
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Ryanair1h 50m006:00Rome Ciampino AirportRome Ciampino Airport07:50Prague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 16/04/2026 06:00:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 16/04/2026 07:50:00. 50 Economy ticket for £24 per person are available. Travel duration is 1h 50m
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Wizz Air1h 55m006:45Rome Fiumicino AirportRome Fiumicino Airport08:40Prague AirportPrague Airport - T1/20EconomyA Flight from Wizz Air goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 16/04/2026 06:45:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 16/04/2026 08:40:00. 50 Economy ticket for £24 per person are available. Travel duration is 1h 55m
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LC Perú1h 55m006:45Rome Fiumicino AirportRome Fiumicino Airport08:40Prague AirportPrague Airport - T1/20EconomyA Flight from LC Perú goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 16/04/2026 06:45:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 16/04/2026 08:40:00. 50 Economy ticket for £27 per person are available. Travel duration is 1h 55m
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Smartwings2h 0m014:00Rome Fiumicino AirportRome Fiumicino Airport16:00Prague AirportPrague Airport - T1/20EconomyA Flight from Smartwings goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 16/04/2026 14:00:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 16/04/2026 16:00:00. 50 Economy ticket for £62 per person are available. Travel duration is 2h 0m
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FlixBus20h 50m017:05RomeTiburtina Bus Station13:55PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 16/04/2026 17:05:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 17/04/2026 13:55:00. 50 Economy ticket for £70 per person are available. Travel duration is 20h 50m
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FlixBus22h 40m010:45Rome Ciampino AirportRome Ciampino Airport09:25PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 16/04/2026 10:45:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 17/04/2026 09:25:00. 50 Economy ticket for £68 per person are available. Travel duration is 22h 40m
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FlixBus24h 0m022:55RomeTiburtina Bus Station22:55PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 16/04/2026 22:55:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 17/04/2026 22:55:00. 50 Economy ticket for £69 per person are available. Travel duration is 24h 0m
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FlixBus27h 40m023:35RomeAnagnina Bus Station03:15PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 16/04/2026 23:35:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 18/04/2026 03:15:00. 50 Economy ticket for £67 per person are available. Travel duration is 27h 40m
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FlixBus27h 55m022:55RomeTiburtina Bus Station02:50PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 16/04/2026 22:55:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 18/04/2026 02:50:00. 50 Economy ticket for £69 per person are available. Travel duration is 27h 55m
Fastest Flights Thursday
Fastest Buses Thursday
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Ryanair1h 50m009:45Rome Ciampino AirportRome Ciampino Airport11:35Prague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 17/04/2026 09:45:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 17/04/2026 11:35:00. 50 Economy ticket for £52 per person are available. Travel duration is 1h 50m
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Skyscanner1h 50m009:45Rome Ciampino AirportRome Ciampino Airport11:35Prague AirportPrague Airport - T1/20EconomyA Flight from Skyscanner goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 17/04/2026 09:45:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 17/04/2026 11:35:00. 50 Economy ticket for £53 per person are available. Travel duration is 1h 50m
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LC Perú1h 55m006:45Rome Fiumicino AirportRome Fiumicino Airport08:40Prague AirportPrague Airport - T1/20EconomyA Flight from LC Perú goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 17/04/2026 06:45:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 17/04/2026 08:40:00. 50 Economy ticket for £63 per person are available. Travel duration is 1h 55m
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Wizz Air5h 5m008:45Rome Fiumicino AirportRome Fiumicino Airport13:50Prague AirportPrague Airport - T1/20EconomyA Flight from Wizz Air goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 17/04/2026 08:45:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 17/04/2026 13:50:00. 50 Economy ticket for £58 per person are available. Travel duration is 5h 5m
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Buzz12h 15m018:35Rome Ciampino AirportRome Ciampino Airport06:50Prague AirportPrague Airport - T1/20EconomyA Flight from Buzz goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 17/04/2026 18:35:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 18/04/2026 06:50:00. 50 Economy ticket for £62 per person are available. Travel duration is 12h 15m
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FlixBus23h 50m010:45Rome Ciampino AirportRome Ciampino Airport10:35PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 17/04/2026 10:45:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 18/04/2026 10:35:00. 50 Economy ticket for £73 per person are available. Travel duration is 23h 50m
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FlixBus24h 20m017:25RomeAnagnina Bus Station17:45PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 17/04/2026 17:25:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 18/04/2026 17:45:00. 50 Economy ticket for £72 per person are available. Travel duration is 24h 20m
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FlixBus25h 35m001:40RomeTiburtina Bus Station03:15PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 17/04/2026 01:40:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 18/04/2026 03:15:00. 50 Economy ticket for £73 per person are available. Travel duration is 25h 35m
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FlixBus26h 55m021:00RomeTiburtina Bus Station23:55PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 17/04/2026 21:00:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 18/04/2026 23:55:00. 50 Economy ticket for £72 per person are available. Travel duration is 26h 55m
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FlixBus27h 40m023:35RomeAnagnina Bus Station03:15PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 17/04/2026 23:35:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 19/04/2026 03:15:00. 50 Economy ticket for £70 per person are available. Travel duration is 27h 40m
Fastest Flights Friday
Fastest Buses Friday
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LC Perú1h 55m006:45Rome Fiumicino AirportRome Fiumicino Airport08:40Prague AirportPrague Airport - T1/20EconomyA Flight from LC Perú goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 18/04/2026 06:45:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 18/04/2026 08:40:00. 50 Economy ticket for £54 per person are available. Travel duration is 1h 55m
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Smartwings2h 0m014:00Rome Fiumicino AirportRome Fiumicino Airport16:00Prague AirportPrague Airport - T1/20EconomyA Flight from Smartwings goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 18/04/2026 14:00:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 18/04/2026 16:00:00. 50 Economy ticket for £62 per person are available. Travel duration is 2h 0m
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Buzz7h 30m009:45Rome Fiumicino AirportRome Fiumicino Airport17:15Prague AirportPrague Airport - T1/20EconomyA Flight from Buzz goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 18/04/2026 09:45:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 18/04/2026 17:15:00. 50 Economy ticket for £85 per person are available. Travel duration is 7h 30m
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Skyscanner9h 50m022:25Rome Fiumicino AirportRome Fiumicino Airport08:15Prague AirportPrague Airport - T1/20EconomyA Flight from Skyscanner goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 18/04/2026 22:25:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 19/04/2026 08:15:00. 50 Economy ticket for £51 per person are available. Travel duration is 9h 50m
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Ryanair22h 15m008:30Rome Ciampino AirportRome Ciampino Airport06:45Prague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 18/04/2026 08:30:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 19/04/2026 06:45:00. 50 Economy ticket for £72 per person are available. Travel duration is 22h 15m
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FlixBus22h 40m010:45Rome Ciampino AirportRome Ciampino Airport09:25PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 18/04/2026 10:45:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 19/04/2026 09:25:00. 50 Economy ticket for £66 per person are available. Travel duration is 22h 40m
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FlixBus23h 50m010:45Rome Ciampino AirportRome Ciampino Airport10:35PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 18/04/2026 10:45:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 19/04/2026 10:35:00. 50 Economy ticket for £69 per person are available. Travel duration is 23h 50m
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FlixBus27h 40m023:35RomeAnagnina Bus Station03:15PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 18/04/2026 23:35:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 20/04/2026 03:15:00. 50 Economy ticket for £65 per person are available. Travel duration is 27h 40m
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FlixBus29h 25m015:30Rome Ciampino AirportRome Ciampino Airport20:55PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 18/04/2026 15:30:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 19/04/2026 20:55:00. 50 Economy ticket for £60 per person are available. Travel duration is 29h 25m
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FlixBus30h 0m015:30Rome Ciampino AirportRome Ciampino Airport21:30PragueČerný Most0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 18/04/2026 15:30:00 to Černý Most, Prague (Czech Republic) arriving at 19/04/2026 21:30:00. 50 Economy ticket for £60 per person are available. Travel duration is 30h 0m
Fastest Flights Saturday
Fastest Buses Saturday
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Wizz Air1h 55m006:45Rome Fiumicino AirportRome Fiumicino Airport08:40Prague AirportPrague Airport - T1/20EconomyA Flight from Wizz Air goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 19/04/2026 06:45:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 19/04/2026 08:40:00. 50 Economy ticket for £43 per person are available. Travel duration is 1h 55m
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ITA Airways8h 15m009:15Rome Fiumicino AirportRome Fiumicino Airport17:30Prague AirportPrague Airport0EconomyA Flight from ITA Airways goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 19/04/2026 09:15:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 19/04/2026 17:30:00. 50 Economy ticket for £117 per person are available. Travel duration is 8h 15m
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Air Serbia11h 40m021:00Rome Fiumicino AirportRome Fiumicino Airport08:40Prague AirportPrague Airport0EconomyA Flight from Air Serbia goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 19/04/2026 21:00:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 20/04/2026 08:40:00. 50 Economy ticket for £114 per person are available. Travel duration is 11h 40m
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EasyJet Airline23h 45m010:40Rome Fiumicino AirportRome Fiumicino Airport10:25Prague AirportPrague Airport0EconomyA Flight from EasyJet Airline goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 19/04/2026 10:40:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 20/04/2026 10:25:00. 50 Economy ticket for £161 per person are available. Travel duration is 23h 45m
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Ryanair26h 40m007:40Rome Ciampino AirportRome Ciampino Airport10:20Prague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 19/04/2026 07:40:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 20/04/2026 10:20:00. 50 Economy ticket for £64 per person are available. Travel duration is 26h 40m
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FlixBus20h 30m021:00RomeTiburtina Bus Station17:30PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 19/04/2026 21:00:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 20/04/2026 17:30:00. 50 Economy ticket for £67 per person are available. Travel duration is 20h 30m
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FlixBus20h 45m021:00RomeTiburtina Bus Station17:45PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 19/04/2026 21:00:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 20/04/2026 17:45:00. 50 Economy ticket for £67 per person are available. Travel duration is 20h 45m
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FlixBus23h 20m021:00RomeTiburtina Bus Station20:20PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 19/04/2026 21:00:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 20/04/2026 20:20:00. 50 Economy ticket for £67 per person are available. Travel duration is 23h 20m
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FlixBus26h 55m021:00RomeTiburtina Bus Station23:55PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 19/04/2026 21:00:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 20/04/2026 23:55:00. 50 Economy ticket for £66 per person are available. Travel duration is 26h 55m
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FlixBus27h 40m023:35RomeAnagnina Bus Station03:15PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 19/04/2026 23:35:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 21/04/2026 03:15:00. 50 Economy ticket for £63 per person are available. Travel duration is 27h 40m
Fastest Flights Sunday
Fastest Buses Sunday
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LC Perú1h 55m006:45Rome Fiumicino AirportRome Fiumicino Airport08:40Prague AirportPrague Airport - T1/20EconomyA Flight from LC Perú goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 20/04/2026 06:45:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 20/04/2026 08:40:00. 50 Economy ticket for £43 per person are available. Travel duration is 1h 55m
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Smartwings2h 0m014:00Rome Fiumicino AirportRome Fiumicino Airport16:00Prague AirportPrague Airport - T1/20EconomyA Flight from Smartwings goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 20/04/2026 14:00:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 20/04/2026 16:00:00. 50 Economy ticket for £75 per person are available. Travel duration is 2h 0m
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Wizz Air6h 5m008:35Rome Fiumicino AirportRome Fiumicino Airport14:40Prague AirportPrague Airport - T1/20EconomyA Flight from Wizz Air goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 20/04/2026 08:35:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 20/04/2026 14:40:00. 50 Economy ticket for £69 per person are available. Travel duration is 6h 5m
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Skyscanner8h 30m006:05Rome Fiumicino AirportRome Fiumicino Airport14:35Prague AirportPrague Airport - T1/20EconomyA Flight from Skyscanner goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 20/04/2026 06:05:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 20/04/2026 14:35:00. 50 Economy ticket for £62 per person are available. Travel duration is 8h 30m
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Ryanair9h 50m007:40Rome Ciampino AirportRome Ciampino Airport17:30Prague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 20/04/2026 07:40:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 20/04/2026 17:30:00. 50 Economy ticket for £58 per person are available. Travel duration is 9h 50m
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FlixBus21h 30m009:30RomeTiburtina Bus Station07:00PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 20/04/2026 09:30:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 21/04/2026 07:00:00. 50 Economy ticket for £58 per person are available. Travel duration is 21h 30m
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FlixBus21h 40m009:30RomeTiburtina Bus Station07:10PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 20/04/2026 09:30:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 21/04/2026 07:10:00. 50 Economy ticket for £58 per person are available. Travel duration is 21h 40m
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FlixBus24h 25m013:05RomeAnagnina Bus Station13:30PragueRoztyly0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 20/04/2026 13:05:00 to Roztyly, Prague (Czech Republic) arriving at 21/04/2026 13:30:00. 50 Economy ticket for £58 per person are available. Travel duration is 24h 25m
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FlixBus29h 25m015:30Rome Ciampino AirportRome Ciampino Airport20:55PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 20/04/2026 15:30:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 21/04/2026 20:55:00. 50 Economy ticket for £53 per person are available. Travel duration is 29h 25m
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FlixBus30h 0m015:30Rome Ciampino AirportRome Ciampino Airport21:30PragueČerný Most0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 20/04/2026 15:30:00 to Černý Most, Prague (Czech Republic) arriving at 21/04/2026 21:30:00. 50 Economy ticket for £53 per person are available. Travel duration is 30h 0m
Fastest Flights Monday
Fastest Buses Monday
Here you will find all operators and timetables for a
Bus from Rome to Prague
What are the most popular stations in Rome and Prague?
In Rome, you will usually depart from Termini Bus Station, Termini Central Station or Ostiense Train Station, while in Prague you will be arriving at Wilsonova Coach Station, ÚAN Florenc or Černý Most, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Prague from Rome? With 10 connections between 1 Flight and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Rome and Prague, you can pay as low as £21 with a Flight from Ryanair.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Ryanair: you will get to Prague in just 1h 50m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Rome and Prague are FlixBus, LC Perú and Wizz Air, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Rome and Prague is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Settebagni or to Horoměřice, and look at flights from Rome Ciampino Airport, and landing at Prague Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Rome to Prague?
The most popular companies between Rome and Prague, are FlixBus, LC Perú and Wizz Air. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: FlixBus
Airlines: LC Perú, Wizz Air, Ryanair and 8 more.
All you need to know when you travel from Rome to Prague
Check all information on comfort and services on all modes of transports from Rome to Prague. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Rome to Prague
How can I reach Prague from Rome?
Every day, there are on average 10 connections between Flight and Bus, with which you can get to Prague from Rome.
How far is Prague from Rome?
The distance between Rome and Prague is 921.0 km.
What is the most ecofriendly mode of transport between Rome and Prague?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 25 kgs of CO2, a train 32 kgs, a car 157 kgs, and a flight 227 kgs.
What is the cheapest mode of transport from Rome to Prague?
You can get to Prague with just £21 by taking a Flight from Ryanair.
What is the fastest way to get from Rome to Prague?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Prague in just 1h 50m with a Flight from Ryanair.
More routes to Rome and to Prague
Looking for more options? Here you can see the most popular routes to Rome and to Prague. Simply click on a connection, and you’ll find all the details about the route!
