What is the best way to travel from Rome to Prague?
Looking for a trip? Check and compare all the available Flights and Buses to Prague from Rome. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 1 available companies to find your perfect trip!
What is the cheapest way to reach Prague from Rome?
You can reach Prague with just £26 by taking a Flight from LC Perú, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
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Skyscanner16h 50m018:05Rome Ciampino AirportRome Ciampino Airport10:55Prague AirportPrague Airport - T1/20EconomyA Flight from Skyscanner goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 05/02/2026 18:05:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 06/02/2026 10:55:00. 50 Economy ticket for £36 per person are available. Travel duration is 16h 50m
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Smartwings2h 0m014:00Rome Fiumicino AirportRome Fiumicino Airport16:00Prague AirportPrague Airport - T1/20EconomyA Flight from Smartwings goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 05/02/2026 14:00:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 05/02/2026 16:00:00. 50 Economy ticket for £52 per person are available. Travel duration is 2h 0m
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Wizz Air9h 45m021:25Rome Fiumicino AirportRome Fiumicino Airport07:10Prague AirportPrague Airport - T1/20EconomyA Flight from Wizz Air goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 05/02/2026 21:25:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 06/02/2026 07:10:00. 50 Economy ticket for £72 per person are available. Travel duration is 9h 45m
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Norwegian Air International22h 30m011:15Rome Fiumicino AirportRome Fiumicino Airport09:45Prague AirportPrague Airport - T1/20EconomyA Flight from Norwegian Air International goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 05/02/2026 11:15:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 06/02/2026 09:45:00. 50 Economy ticket for £91 per person are available. Travel duration is 22h 30m
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EasyJet Airline16h 15m018:05Rome Fiumicino AirportRome Fiumicino Airport10:20Prague AirportPrague Airport0EconomyA Flight from EasyJet Airline goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 05/02/2026 18:05:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 06/02/2026 10:20:00. 50 Economy ticket for £126 per person are available. Travel duration is 16h 15m
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FlixBus22h 40m010:45Rome Ciampino AirportRome Ciampino Airport09:25PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 05/02/2026 10:45:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 06/02/2026 09:25:00. 50 Economy ticket for £59 per person are available. Travel duration is 22h 40m
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FlixBus23h 50m010:45Rome Ciampino AirportRome Ciampino Airport10:35PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 05/02/2026 10:45:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 06/02/2026 10:35:00. 50 Economy ticket for £63 per person are available. Travel duration is 23h 50m
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FlixBus24h 35m012:45RomeAnagnina Bus Station13:20PragueRoztyly0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 05/02/2026 12:45:00 to Roztyly, Prague (Czech Republic) arriving at 06/02/2026 13:20:00. 50 Economy ticket for £65 per person are available. Travel duration is 24h 35m
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FlixBus29h 25m010:45Rome Ciampino AirportRome Ciampino Airport16:10PragueČerný Most0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 05/02/2026 10:45:00 to Černý Most, Prague (Czech Republic) arriving at 06/02/2026 16:10:00. 50 Economy ticket for £68 per person are available. Travel duration is 29h 25m
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FlixBus30h 50m010:45Rome Ciampino AirportRome Ciampino Airport17:35PragueHradčanská0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 05/02/2026 10:45:00 to Hradčanská, Prague (Czech Republic) arriving at 06/02/2026 17:35:00. 50 Economy ticket for £72 per person are available. Travel duration is 30h 50m
Cheapest Flights Thursday
Cheapest Buses Thursday
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FlixBus27h 40m023:35RomeAnagnina Bus Station03:15PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 06/02/2026 23:35:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 08/02/2026 03:15:00. 50 Economy ticket for £62 per person are available. Travel duration is 27h 40m
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FlixBus27h 0m017:00RomeTiburtina Bus Station20:00PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 06/02/2026 17:00:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 07/02/2026 20:00:00. 50 Economy ticket for £64 per person are available. Travel duration is 27h 0m
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FlixBus20h 30m021:00RomeTiburtina Bus Station17:30PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 06/02/2026 21:00:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 07/02/2026 17:30:00. 50 Economy ticket for £64 per person are available. Travel duration is 20h 30m
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FlixBus26h 55m021:00RomeTiburtina Bus Station23:55PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 06/02/2026 21:00:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 07/02/2026 23:55:00. 50 Economy ticket for £64 per person are available. Travel duration is 26h 55m
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FlixBus27h 25m023:50RomeTiburtina Bus Station03:15PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 06/02/2026 23:50:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 08/02/2026 03:15:00. 50 Economy ticket for £64 per person are available. Travel duration is 27h 25m
Cheapest Buses Friday
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FlixBus22h 40m010:45Rome Ciampino AirportRome Ciampino Airport09:25PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 07/02/2026 10:45:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 08/02/2026 09:25:00. 50 Economy ticket for £59 per person are available. Travel duration is 22h 40m
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FlixBus23h 50m010:45Rome Ciampino AirportRome Ciampino Airport10:35PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 07/02/2026 10:45:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 08/02/2026 10:35:00. 50 Economy ticket for £63 per person are available. Travel duration is 23h 50m
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FlixBus22h 45m017:25RomeAnagnina Bus Station16:10PragueČerný Most0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 07/02/2026 17:25:00 to Černý Most, Prague (Czech Republic) arriving at 08/02/2026 16:10:00. 50 Economy ticket for £63 per person are available. Travel duration is 22h 45m
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FlixBus24h 10m017:25RomeAnagnina Bus Station17:35PragueHradčanská0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 07/02/2026 17:25:00 to Hradčanská, Prague (Czech Republic) arriving at 08/02/2026 17:35:00. 50 Economy ticket for £63 per person are available. Travel duration is 24h 10m
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FlixBus27h 0m017:00RomeTiburtina Bus Station20:00PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 07/02/2026 17:00:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 08/02/2026 20:00:00. 50 Economy ticket for £64 per person are available. Travel duration is 27h 0m
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ITA Airways17h 0m015:00Rome Fiumicino AirportRome Fiumicino Airport08:00Prague AirportPrague Airport0EconomyA Flight from ITA Airways goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 07/02/2026 15:00:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 08/02/2026 08:00:00. 50 Economy ticket for £84 per person are available. Travel duration is 17h 0m
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Vueling Airlines15h 30m018:40Rome Fiumicino AirportRome Fiumicino Airport10:10Prague AirportPrague Airport0EconomyA Flight from Vueling Airlines goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 07/02/2026 18:40:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 08/02/2026 10:10:00. 50 Economy ticket for £87 per person are available. Travel duration is 15h 30m
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EasyJet Airline16h 40m019:45Rome Fiumicino AirportRome Fiumicino Airport12:25Prague AirportPrague Airport0EconomyA Flight from EasyJet Airline goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 07/02/2026 19:45:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 08/02/2026 12:25:00. 50 Economy ticket for £115 per person are available. Travel duration is 16h 40m
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Iberia15h 30m018:40Rome Fiumicino AirportRome Fiumicino Airport10:10Prague AirportPrague Airport0EconomyA Flight from Iberia goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 07/02/2026 18:40:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 08/02/2026 10:10:00. 50 Economy ticket for £136 per person are available. Travel duration is 15h 30m
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Lufthansa4h 40m008:25Rome Fiumicino AirportRome Fiumicino Airport13:05Prague AirportPrague Airport0EconomyA Flight from Lufthansa goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 07/02/2026 08:25:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 07/02/2026 13:05:00. 50 Economy ticket for £211 per person are available. Travel duration is 4h 40m
Cheapest Buses Saturday
Cheapest Flights Saturday
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LC Perú2h 0m006:40Rome Fiumicino AirportRome Fiumicino Airport08:40Prague AirportPrague Airport - T1/20EconomyA Flight from LC Perú goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 08/02/2026 06:40:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 08/02/2026 08:40:00. 50 Economy ticket for £26 per person are available. Travel duration is 2h 0m
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Skyscanner1h 50m016:25Rome Ciampino AirportRome Ciampino Airport18:15Prague AirportPrague Airport - T1/20EconomyA Flight from Skyscanner goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 08/02/2026 16:25:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 08/02/2026 18:15:00. 50 Economy ticket for £42 per person are available. Travel duration is 1h 50m
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Buzz1h 50m008:35Rome Ciampino AirportRome Ciampino Airport10:25Prague AirportPrague Airport - T1/20EconomyA Flight from Buzz goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 08/02/2026 08:35:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 08/02/2026 10:25:00. 50 Economy ticket for £43 per person are available. Travel duration is 1h 50m
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Smartwings2h 0m014:00Rome Fiumicino AirportRome Fiumicino Airport16:00Prague AirportPrague Airport - T1/20EconomyA Flight from Smartwings goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 08/02/2026 14:00:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 08/02/2026 16:00:00. 50 Economy ticket for £52 per person are available. Travel duration is 2h 0m
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Wizz Air19h 5m021:30Rome Fiumicino AirportRome Fiumicino Airport16:35Prague AirportPrague Airport0EconomyA Flight from Wizz Air goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 08/02/2026 21:30:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 09/02/2026 16:35:00. 50 Economy ticket for £84 per person are available. Travel duration is 19h 5m
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FlixBus27h 40m023:35RomeAnagnina Bus Station03:15PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 08/02/2026 23:35:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 10/02/2026 03:15:00. 50 Economy ticket for £63 per person are available. Travel duration is 27h 40m
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FlixBus25h 35m001:40RomeTiburtina Bus Station03:15PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 08/02/2026 01:40:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 09/02/2026 03:15:00. 50 Economy ticket for £64 per person are available. Travel duration is 25h 35m
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FlixBus27h 0m017:00RomeTiburtina Bus Station20:00PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 08/02/2026 17:00:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 09/02/2026 20:00:00. 50 Economy ticket for £64 per person are available. Travel duration is 27h 0m
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FlixBus20h 30m021:00RomeTiburtina Bus Station17:30PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 08/02/2026 21:00:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 09/02/2026 17:30:00. 50 Economy ticket for £64 per person are available. Travel duration is 20h 30m
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FlixBus26h 55m021:00RomeTiburtina Bus Station23:55PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 08/02/2026 21:00:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 09/02/2026 23:55:00. 50 Economy ticket for £64 per person are available. Travel duration is 26h 55m
Cheapest Flights Sunday
Cheapest Buses Sunday
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FlixBus20h 45m009:30RomeTiburtina Bus Station06:15PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 09/02/2026 09:30:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 10/02/2026 06:15:00. 50 Economy ticket for £61 per person are available. Travel duration is 20h 45m
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FlixBus20h 45m021:00RomeTiburtina Bus Station17:45PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 09/02/2026 21:00:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 10/02/2026 17:45:00. 50 Economy ticket for £61 per person are available. Travel duration is 20h 45m
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FlixBus24h 40m021:20RomeTiburtina Bus Station22:00PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 09/02/2026 21:20:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 10/02/2026 22:00:00. 50 Economy ticket for £61 per person are available. Travel duration is 24h 40m
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FlixBus20h 30m009:30RomeTiburtina Bus Station06:00PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 09/02/2026 09:30:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 10/02/2026 06:00:00. 50 Economy ticket for £61 per person are available. Travel duration is 20h 30m
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FlixBus27h 0m017:00RomeTiburtina Bus Station20:00PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 09/02/2026 17:00:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 10/02/2026 20:00:00. 50 Economy ticket for £61 per person are available. Travel duration is 27h 0m
Cheapest Buses Monday
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Skyscanner1h 50m006:15Rome Ciampino AirportRome Ciampino Airport08:05Prague AirportPrague Airport - T1/20EconomyA Flight from Skyscanner goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 10/02/2026 06:15:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 10/02/2026 08:05:00. 50 Economy ticket for £29 per person are available. Travel duration is 1h 50m
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LC Perú2h 0m006:40Rome Fiumicino AirportRome Fiumicino Airport08:40Prague AirportPrague Airport - T1/20EconomyA Flight from LC Perú goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 10/02/2026 06:40:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 10/02/2026 08:40:00. 50 Economy ticket for £35 per person are available. Travel duration is 2h 0m
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Ryanair11h 25m009:30Rome Ciampino AirportRome Ciampino Airport20:55Prague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 10/02/2026 09:30:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 10/02/2026 20:55:00. 50 Economy ticket for £50 per person are available. Travel duration is 11h 25m
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Air Malta10h 55m008:55Rome Fiumicino AirportRome Fiumicino Airport19:50Prague AirportPrague Airport - T1/20EconomyA Flight from Air Malta goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 10/02/2026 08:55:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 10/02/2026 19:50:00. 50 Economy ticket for £84 per person are available. Travel duration is 10h 55m
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Siam Air Transport11h 20m021:10Rome Fiumicino AirportRome Fiumicino Airport08:30Prague AirportPrague Airport - T1/20EconomyA Flight from Siam Air Transport goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 10/02/2026 21:10:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 11/02/2026 08:30:00. 50 Economy ticket for £85 per person are available. Travel duration is 11h 20m
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FlixBus20h 30m021:00RomeTiburtina Bus Station17:30PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 10/02/2026 21:00:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 11/02/2026 17:30:00. 50 Economy ticket for £55 per person are available. Travel duration is 20h 30m
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FlixBus20h 45m021:00RomeTiburtina Bus Station17:45PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 10/02/2026 21:00:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 11/02/2026 17:45:00. 50 Economy ticket for £55 per person are available. Travel duration is 20h 45m
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FlixBus24h 15m013:05RomeAnagnina Bus Station13:20PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 10/02/2026 13:05:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 11/02/2026 13:20:00. 50 Economy ticket for £55 per person are available. Travel duration is 24h 15m
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FlixBus24h 25m013:05RomeAnagnina Bus Station13:30PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 10/02/2026 13:05:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 11/02/2026 13:30:00. 50 Economy ticket for £55 per person are available. Travel duration is 24h 25m
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FlixBus23h 20m021:00RomeTiburtina Bus Station20:20PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 10/02/2026 21:00:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 11/02/2026 20:20:00. 50 Economy ticket for £55 per person are available. Travel duration is 23h 20m
Cheapest Flights Tuesday
Cheapest Buses Tuesday
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FlixBus20h 30m021:00RomeTiburtina Bus Station17:30PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 11/02/2026 21:00:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 12/02/2026 17:30:00. 50 Economy ticket for £55 per person are available. Travel duration is 20h 30m
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FlixBus26h 55m021:00RomeTiburtina Bus Station23:55PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 11/02/2026 21:00:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 12/02/2026 23:55:00. 50 Economy ticket for £55 per person are available. Travel duration is 26h 55m
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FlixBus20h 25m022:55RomeTiburtina Bus Station19:20PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 11/02/2026 22:55:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 12/02/2026 19:20:00. 50 Economy ticket for £55 per person are available. Travel duration is 20h 25m
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FlixBus20h 45m021:00RomeTiburtina Bus Station17:45PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 11/02/2026 21:00:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 12/02/2026 17:45:00. 50 Economy ticket for £55 per person are available. Travel duration is 20h 45m
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FlixBus20h 35m022:55RomeTiburtina Bus Station19:30PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 11/02/2026 22:55:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 12/02/2026 19:30:00. 50 Economy ticket for £55 per person are available. Travel duration is 20h 35m
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EasyJet Airline23h 15m017:30Rome Fiumicino AirportRome Fiumicino Airport16:45Prague AirportPrague Airport0EconomyA Flight from EasyJet Airline goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 11/02/2026 17:30:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 12/02/2026 16:45:00. 50 Economy ticket for £108 per person are available. Travel duration is 23h 15m
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ITA Airways14h 10m006:30Rome Fiumicino AirportRome Fiumicino Airport20:40Prague AirportPrague Airport0EconomyA Flight from ITA Airways goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 11/02/2026 06:30:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 11/02/2026 20:40:00. 50 Economy ticket for £109 per person are available. Travel duration is 14h 10m
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Air Serbia12h 5m020:40Rome Fiumicino AirportRome Fiumicino Airport08:45Prague AirportPrague Airport0EconomyA Flight from Air Serbia goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 11/02/2026 20:40:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 12/02/2026 08:45:00. 50 Economy ticket for £110 per person are available. Travel duration is 12h 5m
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Wizz Air13h 5m018:10Rome Fiumicino AirportRome Fiumicino Airport07:15Prague AirportPrague Airport0EconomyA Flight from Wizz Air goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 11/02/2026 18:10:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 12/02/2026 07:15:00. 50 Economy ticket for £118 per person are available. Travel duration is 13h 5m
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Vueling Airlines16h 0m018:10Rome Fiumicino AirportRome Fiumicino Airport10:10Prague AirportPrague Airport0EconomyA Flight from Vueling Airlines goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 11/02/2026 18:10:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 12/02/2026 10:10:00. 50 Economy ticket for £124 per person are available. Travel duration is 16h 0m
Cheapest Buses Wednesday
Cheapest Flights Wednesday
What are the fastest trips from Rome to Prague?
You can get to Prague from Rome in just 1h 50m with a Flight from Skyscanner. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
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Smartwings2h 0m014:00Rome Fiumicino AirportRome Fiumicino Airport16:00Prague AirportPrague Airport - T1/20EconomyA Flight from Smartwings goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 05/02/2026 14:00:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 05/02/2026 16:00:00. 50 Economy ticket for £52 per person are available. Travel duration is 2h 0m
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Wizz Air9h 45m021:25Rome Fiumicino AirportRome Fiumicino Airport07:10Prague AirportPrague Airport - T1/20EconomyA Flight from Wizz Air goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 05/02/2026 21:25:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 06/02/2026 07:10:00. 50 Economy ticket for £72 per person are available. Travel duration is 9h 45m
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EasyJet Airline16h 15m018:05Rome Fiumicino AirportRome Fiumicino Airport10:20Prague AirportPrague Airport0EconomyA Flight from EasyJet Airline goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 05/02/2026 18:05:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 06/02/2026 10:20:00. 50 Economy ticket for £126 per person are available. Travel duration is 16h 15m
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Skyscanner16h 50m018:05Rome Ciampino AirportRome Ciampino Airport10:55Prague AirportPrague Airport - T1/20EconomyA Flight from Skyscanner goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 05/02/2026 18:05:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 06/02/2026 10:55:00. 50 Economy ticket for £36 per person are available. Travel duration is 16h 50m
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Norwegian Air International22h 30m011:15Rome Fiumicino AirportRome Fiumicino Airport09:45Prague AirportPrague Airport - T1/20EconomyA Flight from Norwegian Air International goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 05/02/2026 11:15:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 06/02/2026 09:45:00. 50 Economy ticket for £91 per person are available. Travel duration is 22h 30m
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FlixBus22h 40m010:45Rome Ciampino AirportRome Ciampino Airport09:25PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 05/02/2026 10:45:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 06/02/2026 09:25:00. 50 Economy ticket for £59 per person are available. Travel duration is 22h 40m
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FlixBus23h 50m010:45Rome Ciampino AirportRome Ciampino Airport10:35PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 05/02/2026 10:45:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 06/02/2026 10:35:00. 50 Economy ticket for £63 per person are available. Travel duration is 23h 50m
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FlixBus24h 35m012:45RomeAnagnina Bus Station13:20PragueRoztyly0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 05/02/2026 12:45:00 to Roztyly, Prague (Czech Republic) arriving at 06/02/2026 13:20:00. 50 Economy ticket for £65 per person are available. Travel duration is 24h 35m
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FlixBus29h 25m010:45Rome Ciampino AirportRome Ciampino Airport16:10PragueČerný Most0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 05/02/2026 10:45:00 to Černý Most, Prague (Czech Republic) arriving at 06/02/2026 16:10:00. 50 Economy ticket for £68 per person are available. Travel duration is 29h 25m
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FlixBus30h 50m010:45Rome Ciampino AirportRome Ciampino Airport17:35PragueHradčanská0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 05/02/2026 10:45:00 to Hradčanská, Prague (Czech Republic) arriving at 06/02/2026 17:35:00. 50 Economy ticket for £72 per person are available. Travel duration is 30h 50m
Fastest Flights Thursday
Fastest Buses Thursday
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FlixBus20h 30m021:00RomeTiburtina Bus Station17:30PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 06/02/2026 21:00:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 07/02/2026 17:30:00. 50 Economy ticket for £64 per person are available. Travel duration is 20h 30m
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FlixBus26h 55m021:00RomeTiburtina Bus Station23:55PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 06/02/2026 21:00:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 07/02/2026 23:55:00. 50 Economy ticket for £64 per person are available. Travel duration is 26h 55m
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FlixBus27h 0m017:00RomeTiburtina Bus Station20:00PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 06/02/2026 17:00:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 07/02/2026 20:00:00. 50 Economy ticket for £64 per person are available. Travel duration is 27h 0m
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FlixBus27h 25m023:50RomeTiburtina Bus Station03:15PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 06/02/2026 23:50:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 08/02/2026 03:15:00. 50 Economy ticket for £64 per person are available. Travel duration is 27h 25m
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FlixBus27h 40m023:35RomeAnagnina Bus Station03:15PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 06/02/2026 23:35:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 08/02/2026 03:15:00. 50 Economy ticket for £62 per person are available. Travel duration is 27h 40m
Fastest Buses Friday
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Lufthansa4h 40m008:25Rome Fiumicino AirportRome Fiumicino Airport13:05Prague AirportPrague Airport0EconomyA Flight from Lufthansa goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 07/02/2026 08:25:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 07/02/2026 13:05:00. 50 Economy ticket for £211 per person are available. Travel duration is 4h 40m
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Vueling Airlines15h 30m018:40Rome Fiumicino AirportRome Fiumicino Airport10:10Prague AirportPrague Airport0EconomyA Flight from Vueling Airlines goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 07/02/2026 18:40:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 08/02/2026 10:10:00. 50 Economy ticket for £87 per person are available. Travel duration is 15h 30m
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Iberia15h 30m018:40Rome Fiumicino AirportRome Fiumicino Airport10:10Prague AirportPrague Airport0EconomyA Flight from Iberia goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 07/02/2026 18:40:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 08/02/2026 10:10:00. 50 Economy ticket for £136 per person are available. Travel duration is 15h 30m
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EasyJet Airline16h 40m019:45Rome Fiumicino AirportRome Fiumicino Airport12:25Prague AirportPrague Airport0EconomyA Flight from EasyJet Airline goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 07/02/2026 19:45:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 08/02/2026 12:25:00. 50 Economy ticket for £115 per person are available. Travel duration is 16h 40m
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ITA Airways17h 0m015:00Rome Fiumicino AirportRome Fiumicino Airport08:00Prague AirportPrague Airport0EconomyA Flight from ITA Airways goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 07/02/2026 15:00:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 08/02/2026 08:00:00. 50 Economy ticket for £84 per person are available. Travel duration is 17h 0m
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FlixBus22h 40m010:45Rome Ciampino AirportRome Ciampino Airport09:25PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 07/02/2026 10:45:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 08/02/2026 09:25:00. 50 Economy ticket for £59 per person are available. Travel duration is 22h 40m
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FlixBus22h 45m017:25RomeAnagnina Bus Station16:10PragueČerný Most0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 07/02/2026 17:25:00 to Černý Most, Prague (Czech Republic) arriving at 08/02/2026 16:10:00. 50 Economy ticket for £63 per person are available. Travel duration is 22h 45m
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FlixBus23h 50m010:45Rome Ciampino AirportRome Ciampino Airport10:35PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 07/02/2026 10:45:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 08/02/2026 10:35:00. 50 Economy ticket for £63 per person are available. Travel duration is 23h 50m
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FlixBus24h 10m017:25RomeAnagnina Bus Station17:35PragueHradčanská0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 07/02/2026 17:25:00 to Hradčanská, Prague (Czech Republic) arriving at 08/02/2026 17:35:00. 50 Economy ticket for £63 per person are available. Travel duration is 24h 10m
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FlixBus27h 0m017:00RomeTiburtina Bus Station20:00PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 07/02/2026 17:00:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 08/02/2026 20:00:00. 50 Economy ticket for £64 per person are available. Travel duration is 27h 0m
Fastest Flights Saturday
Fastest Buses Saturday
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Skyscanner1h 50m016:25Rome Ciampino AirportRome Ciampino Airport18:15Prague AirportPrague Airport - T1/20EconomyA Flight from Skyscanner goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 08/02/2026 16:25:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 08/02/2026 18:15:00. 50 Economy ticket for £42 per person are available. Travel duration is 1h 50m
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Buzz1h 50m008:35Rome Ciampino AirportRome Ciampino Airport10:25Prague AirportPrague Airport - T1/20EconomyA Flight from Buzz goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 08/02/2026 08:35:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 08/02/2026 10:25:00. 50 Economy ticket for £43 per person are available. Travel duration is 1h 50m
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LC Perú2h 0m006:40Rome Fiumicino AirportRome Fiumicino Airport08:40Prague AirportPrague Airport - T1/20EconomyA Flight from LC Perú goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 08/02/2026 06:40:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 08/02/2026 08:40:00. 50 Economy ticket for £26 per person are available. Travel duration is 2h 0m
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Smartwings2h 0m014:00Rome Fiumicino AirportRome Fiumicino Airport16:00Prague AirportPrague Airport - T1/20EconomyA Flight from Smartwings goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 08/02/2026 14:00:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 08/02/2026 16:00:00. 50 Economy ticket for £52 per person are available. Travel duration is 2h 0m
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Wizz Air19h 5m021:30Rome Fiumicino AirportRome Fiumicino Airport16:35Prague AirportPrague Airport0EconomyA Flight from Wizz Air goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 08/02/2026 21:30:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 09/02/2026 16:35:00. 50 Economy ticket for £84 per person are available. Travel duration is 19h 5m
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FlixBus20h 30m021:00RomeTiburtina Bus Station17:30PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 08/02/2026 21:00:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 09/02/2026 17:30:00. 50 Economy ticket for £64 per person are available. Travel duration is 20h 30m
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FlixBus25h 35m001:40RomeTiburtina Bus Station03:15PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 08/02/2026 01:40:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 09/02/2026 03:15:00. 50 Economy ticket for £64 per person are available. Travel duration is 25h 35m
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FlixBus26h 55m021:00RomeTiburtina Bus Station23:55PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 08/02/2026 21:00:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 09/02/2026 23:55:00. 50 Economy ticket for £64 per person are available. Travel duration is 26h 55m
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FlixBus27h 0m017:00RomeTiburtina Bus Station20:00PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 08/02/2026 17:00:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 09/02/2026 20:00:00. 50 Economy ticket for £64 per person are available. Travel duration is 27h 0m
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FlixBus27h 40m023:35RomeAnagnina Bus Station03:15PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 08/02/2026 23:35:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 10/02/2026 03:15:00. 50 Economy ticket for £63 per person are available. Travel duration is 27h 40m
Fastest Flights Sunday
Fastest Buses Sunday
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FlixBus20h 30m009:30RomeTiburtina Bus Station06:00PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 09/02/2026 09:30:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 10/02/2026 06:00:00. 50 Economy ticket for £61 per person are available. Travel duration is 20h 30m
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FlixBus20h 45m009:30RomeTiburtina Bus Station06:15PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 09/02/2026 09:30:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 10/02/2026 06:15:00. 50 Economy ticket for £61 per person are available. Travel duration is 20h 45m
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FlixBus20h 45m021:00RomeTiburtina Bus Station17:45PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 09/02/2026 21:00:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 10/02/2026 17:45:00. 50 Economy ticket for £61 per person are available. Travel duration is 20h 45m
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FlixBus24h 40m021:20RomeTiburtina Bus Station22:00PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 09/02/2026 21:20:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 10/02/2026 22:00:00. 50 Economy ticket for £61 per person are available. Travel duration is 24h 40m
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FlixBus27h 0m017:00RomeTiburtina Bus Station20:00PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 09/02/2026 17:00:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 10/02/2026 20:00:00. 50 Economy ticket for £61 per person are available. Travel duration is 27h 0m
Fastest Buses Monday
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Skyscanner1h 50m006:15Rome Ciampino AirportRome Ciampino Airport08:05Prague AirportPrague Airport - T1/20EconomyA Flight from Skyscanner goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 10/02/2026 06:15:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 10/02/2026 08:05:00. 50 Economy ticket for £29 per person are available. Travel duration is 1h 50m
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LC Perú2h 0m006:40Rome Fiumicino AirportRome Fiumicino Airport08:40Prague AirportPrague Airport - T1/20EconomyA Flight from LC Perú goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 10/02/2026 06:40:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 10/02/2026 08:40:00. 50 Economy ticket for £35 per person are available. Travel duration is 2h 0m
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Air Malta10h 55m008:55Rome Fiumicino AirportRome Fiumicino Airport19:50Prague AirportPrague Airport - T1/20EconomyA Flight from Air Malta goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 10/02/2026 08:55:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 10/02/2026 19:50:00. 50 Economy ticket for £84 per person are available. Travel duration is 10h 55m
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Siam Air Transport11h 20m021:10Rome Fiumicino AirportRome Fiumicino Airport08:30Prague AirportPrague Airport - T1/20EconomyA Flight from Siam Air Transport goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 10/02/2026 21:10:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 11/02/2026 08:30:00. 50 Economy ticket for £85 per person are available. Travel duration is 11h 20m
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Ryanair11h 25m009:30Rome Ciampino AirportRome Ciampino Airport20:55Prague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 10/02/2026 09:30:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 10/02/2026 20:55:00. 50 Economy ticket for £50 per person are available. Travel duration is 11h 25m
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FlixBus20h 30m021:00RomeTiburtina Bus Station17:30PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 10/02/2026 21:00:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 11/02/2026 17:30:00. 50 Economy ticket for £55 per person are available. Travel duration is 20h 30m
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FlixBus20h 45m021:00RomeTiburtina Bus Station17:45PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 10/02/2026 21:00:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 11/02/2026 17:45:00. 50 Economy ticket for £55 per person are available. Travel duration is 20h 45m
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FlixBus23h 20m021:00RomeTiburtina Bus Station20:20PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 10/02/2026 21:00:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 11/02/2026 20:20:00. 50 Economy ticket for £55 per person are available. Travel duration is 23h 20m
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FlixBus24h 15m013:05RomeAnagnina Bus Station13:20PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 10/02/2026 13:05:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 11/02/2026 13:20:00. 50 Economy ticket for £55 per person are available. Travel duration is 24h 15m
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FlixBus24h 25m013:05RomeAnagnina Bus Station13:30PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 10/02/2026 13:05:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 11/02/2026 13:30:00. 50 Economy ticket for £55 per person are available. Travel duration is 24h 25m
Fastest Flights Tuesday
Fastest Buses Tuesday
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Air Serbia12h 5m020:40Rome Fiumicino AirportRome Fiumicino Airport08:45Prague AirportPrague Airport0EconomyA Flight from Air Serbia goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 11/02/2026 20:40:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 12/02/2026 08:45:00. 50 Economy ticket for £110 per person are available. Travel duration is 12h 5m
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Wizz Air13h 5m018:10Rome Fiumicino AirportRome Fiumicino Airport07:15Prague AirportPrague Airport0EconomyA Flight from Wizz Air goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 11/02/2026 18:10:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 12/02/2026 07:15:00. 50 Economy ticket for £118 per person are available. Travel duration is 13h 5m
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ITA Airways14h 10m006:30Rome Fiumicino AirportRome Fiumicino Airport20:40Prague AirportPrague Airport0EconomyA Flight from ITA Airways goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 11/02/2026 06:30:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 11/02/2026 20:40:00. 50 Economy ticket for £109 per person are available. Travel duration is 14h 10m
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Vueling Airlines16h 0m018:10Rome Fiumicino AirportRome Fiumicino Airport10:10Prague AirportPrague Airport0EconomyA Flight from Vueling Airlines goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 11/02/2026 18:10:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 12/02/2026 10:10:00. 50 Economy ticket for £124 per person are available. Travel duration is 16h 0m
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EasyJet Airline23h 15m017:30Rome Fiumicino AirportRome Fiumicino Airport16:45Prague AirportPrague Airport0EconomyA Flight from EasyJet Airline goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 11/02/2026 17:30:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 12/02/2026 16:45:00. 50 Economy ticket for £108 per person are available. Travel duration is 23h 15m
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FlixBus20h 25m022:55RomeTiburtina Bus Station19:20PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 11/02/2026 22:55:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 12/02/2026 19:20:00. 50 Economy ticket for £55 per person are available. Travel duration is 20h 25m
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FlixBus20h 30m021:00RomeTiburtina Bus Station17:30PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 11/02/2026 21:00:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 12/02/2026 17:30:00. 50 Economy ticket for £55 per person are available. Travel duration is 20h 30m
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FlixBus20h 35m022:55RomeTiburtina Bus Station19:30PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 11/02/2026 22:55:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 12/02/2026 19:30:00. 50 Economy ticket for £55 per person are available. Travel duration is 20h 35m
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FlixBus20h 45m021:00RomeTiburtina Bus Station17:45PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 11/02/2026 21:00:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 12/02/2026 17:45:00. 50 Economy ticket for £55 per person are available. Travel duration is 20h 45m
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FlixBus26h 55m021:00RomeTiburtina Bus Station23:55PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 11/02/2026 21:00:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 12/02/2026 23:55:00. 50 Economy ticket for £55 per person are available. Travel duration is 26h 55m
Fastest Flights Wednesday
Fastest Buses Wednesday
Here you will find all operators and timetables for a
Bus from Rome to Prague
What are the most popular stations in Rome and Prague?
In Rome, you will usually depart from Termini Bus Station, Ostiense Train Station or Termini Central Station, while in Prague you will be arriving at Wilsonova Coach Station, ÚAN Florenc or Černý Most, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Prague from Rome? With 8 connections between 1 Flight and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Rome and Prague, you can pay as low as £26 with a Flight from LC Perú.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Skyscanner: you will get to Prague in just 1h 50m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Rome and Prague are FlixBus, Skyscanner and Wizz Air, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Rome and Prague is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Settebagni or to Horoměřice, and look at flights from Rome Ciampino Airport, and landing at Prague Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Rome to Prague?
The most popular companies between Rome and Prague, are FlixBus, Skyscanner and Wizz Air. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: FlixBus
Airlines: Skyscanner, Wizz Air, EasyJet Airline and 12 more.
All you need to know when you travel from Rome to Prague
Check all information on comfort and services on all modes of transports from Rome to Prague. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Rome to Prague
How can I reach Prague from Rome?
Every day, there are on average 8 connections between Flight and Bus, with which you can get to Prague from Rome.
How far is Prague from Rome?
The distance between Rome and Prague is 921.0 km.
What is the most ecofriendly mode of transport between Rome and Prague?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 25 kgs of CO2, a train 32 kgs, a car 157 kgs, and a flight 227 kgs.
What is the cheapest mode of transport from Rome to Prague?
You can get to Prague with just £26 by taking a Flight from LC Perú.
What is the fastest way to get from Rome to Prague?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Prague in just 1h 50m with a Flight from Skyscanner.
More routes to Rome and to Prague
Looking for more options? Here you can see the most popular routes to Rome and to Prague. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Rome
- Alba Adriatica to Rome
- Avellino to Rome
- Bari to Rome
- Battipaglia to Rome
- Caserta to Rome
- Cassino to Rome
- Catanzaro to Rome
- Chieti to Rome
- Civitanova to Rome
- Grottaminarda to Rome
- L'Aquila to Rome
- Lamezia Terme to Rome
- Lecce to Rome
- Marseille to Rome
- Milan to Rome
- Mosciano Sant'Angelo to Rome
- Naples to Rome
- Perugia to Rome
- Pescara to Rome
- Rome Fiumicino Airport to Rome
- Sala Consilina to Rome
- Salerno to Rome
- San Benedetto del Tronto to Rome
- Venice to Rome
- Trips to Prague
- Amsterdam Schiphol Airport to Prague
- Amsterdam to Prague
- Bern to Prague
- Bologna to Prague
- Bratislava to Prague
- Brno to Prague
- Brussels to Prague
- Florence to Prague
- Hamburg to Prague
- Heidelberg to Prague
- Hradec Kralove to Prague
- Jihlava to Prague
- Karlovy Vary to Prague
- Katowice to Prague
- Kosice to Prague
- Linz to Prague
- Munich Airport to Prague
- Nuremberg to Prague
- Paris to Prague
- Pilsen to Prague
- St. Gallen to Prague
- Třebíč to Prague
- Warsaw to Prague
- Wroclaw to Prague
