What is the best way to travel from Rome to Prague?
Looking for a trip? Check and compare all the available Flights and Buses to Prague from Rome. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 1 available companies to find your perfect trip!
What is the cheapest way to reach Prague from Rome?
You can reach Prague with just £10 by taking a Flight from Wizz Air, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
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Skyscanner1h 50m006:00Rome Ciampino AirportRome Ciampino Airport07:50Prague AirportPrague Airport - T1/20EconomyA Flight from Skyscanner goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 03/06/2026 06:00:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 03/06/2026 07:50:00. 50 Economy ticket for £17 per person are available. Travel duration is 1h 50m
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Ryanair1h 50m006:00Rome Ciampino AirportRome Ciampino Airport07:50Prague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 03/06/2026 06:00:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 03/06/2026 07:50:00. 50 Economy ticket for £18 per person are available. Travel duration is 1h 50m
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LC Perú1h 55m006:45Rome Fiumicino AirportRome Fiumicino Airport08:40Prague AirportPrague Airport - T1/20EconomyA Flight from LC Perú goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 03/06/2026 06:45:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 03/06/2026 08:40:00. 50 Economy ticket for £29 per person are available. Travel duration is 1h 55m
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Buzz7h 45m010:40Rome Ciampino AirportRome Ciampino Airport18:25Prague AirportPrague Airport - T1/20EconomyA Flight from Buzz goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 03/06/2026 10:40:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 03/06/2026 18:25:00. 50 Economy ticket for £41 per person are available. Travel duration is 7h 45m
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Condor4h 50m011:10Rome Fiumicino AirportRome Fiumicino Airport16:00Prague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 03/06/2026 11:10:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 03/06/2026 16:00:00. 50 Economy ticket for £68 per person are available. Travel duration is 4h 50m
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FlixBus24h 0m022:55RomeTiburtina Bus Station22:55PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 03/06/2026 22:55:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 04/06/2026 22:55:00. 50 Economy ticket for £95 per person are available. Travel duration is 24h 0m
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FlixBus26h 55m021:00RomeTiburtina Bus Station23:55PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 03/06/2026 21:00:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 04/06/2026 23:55:00. 50 Economy ticket for £95 per person are available. Travel duration is 26h 55m
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FlixBus20h 25m022:55RomeTiburtina Bus Station19:20PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 03/06/2026 22:55:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 04/06/2026 19:20:00. 50 Economy ticket for £96 per person are available. Travel duration is 20h 25m
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FlixBus20h 35m022:55RomeTiburtina Bus Station19:30PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 03/06/2026 22:55:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 04/06/2026 19:30:00. 50 Economy ticket for £96 per person are available. Travel duration is 20h 35m
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FlixBus25h 0m012:20RomeTiburtina Bus Station13:20PragueRoztyly0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 03/06/2026 12:20:00 to Roztyly, Prague (Czech Republic) arriving at 04/06/2026 13:20:00. 50 Economy ticket for £97 per person are available. Travel duration is 25h 0m
Cheapest Flights Wednesday
Cheapest Buses Wednesday
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Skyscanner1h 50m006:00Rome Ciampino AirportRome Ciampino Airport07:50Prague AirportPrague Airport - T1/20EconomyA Flight from Skyscanner goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 04/06/2026 06:00:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 04/06/2026 07:50:00. 50 Economy ticket for £17 per person are available. Travel duration is 1h 50m
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Ryanair1h 50m006:00Rome Ciampino AirportRome Ciampino Airport07:50Prague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 04/06/2026 06:00:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 04/06/2026 07:50:00. 50 Economy ticket for £18 per person are available. Travel duration is 1h 50m
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LC Perú1h 55m006:45Rome Fiumicino AirportRome Fiumicino Airport08:40Prague AirportPrague Airport - T1/20EconomyA Flight from LC Perú goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 04/06/2026 06:45:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 04/06/2026 08:40:00. 50 Economy ticket for £26 per person are available. Travel duration is 1h 55m
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Buzz14h 25m016:35Rome Ciampino AirportRome Ciampino Airport07:00Prague AirportPrague Airport - T1/20EconomyA Flight from Buzz goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 04/06/2026 16:35:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 05/06/2026 07:00:00. 50 Economy ticket for £38 per person are available. Travel duration is 14h 25m
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Wizz Air9h 50m021:10Rome Fiumicino AirportRome Fiumicino Airport07:00Prague AirportPrague Airport - T1/20EconomyA Flight from Wizz Air goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 04/06/2026 21:10:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 05/06/2026 07:00:00. 50 Economy ticket for £57 per person are available. Travel duration is 9h 50m
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FlixBus22h 40m010:45Rome Ciampino AirportRome Ciampino Airport09:25PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 04/06/2026 10:45:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 05/06/2026 09:25:00. 50 Economy ticket for £76 per person are available. Travel duration is 22h 40m
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FlixBus20h 50m017:05RomeTiburtina Bus Station13:55PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 04/06/2026 17:05:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 05/06/2026 13:55:00. 50 Economy ticket for £79 per person are available. Travel duration is 20h 50m
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FlixBus20h 40m017:05RomeTiburtina Bus Station13:45PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 04/06/2026 17:05:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 05/06/2026 13:45:00. 50 Economy ticket for £79 per person are available. Travel duration is 20h 40m
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FlixBus25h 25m012:20RomeTiburtina Bus Station13:45PragueČerný Most0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 04/06/2026 12:20:00 to Černý Most, Prague (Czech Republic) arriving at 05/06/2026 13:45:00. 50 Economy ticket for £79 per person are available. Travel duration is 25h 25m
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FlixBus27h 40m023:35RomeAnagnina Bus Station03:15PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 04/06/2026 23:35:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 06/06/2026 03:15:00. 50 Economy ticket for £79 per person are available. Travel duration is 27h 40m
Cheapest Flights Thursday
Cheapest Buses Thursday
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Skyscanner1h 50m017:30Rome Ciampino AirportRome Ciampino Airport19:20Prague AirportPrague Airport - T1/20EconomyA Flight from Skyscanner goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 05/06/2026 17:30:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 05/06/2026 19:20:00. 50 Economy ticket for £25 per person are available. Travel duration is 1h 50m
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LC Perú1h 55m006:45Rome Fiumicino AirportRome Fiumicino Airport08:40Prague AirportPrague Airport - T1/20EconomyA Flight from LC Perú goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 05/06/2026 06:45:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 05/06/2026 08:40:00. 50 Economy ticket for £25 per person are available. Travel duration is 1h 55m
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Wizz Air1h 55m006:45Rome Fiumicino AirportRome Fiumicino Airport08:40Prague AirportPrague Airport - T1/20EconomyA Flight from Wizz Air goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 05/06/2026 06:45:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 05/06/2026 08:40:00. 50 Economy ticket for £25 per person are available. Travel duration is 1h 55m
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Ryanair1h 50m017:30Rome Ciampino AirportRome Ciampino Airport19:20Prague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 05/06/2026 17:30:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 05/06/2026 19:20:00. 50 Economy ticket for £30 per person are available. Travel duration is 1h 50m
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Smartwings2h 0m014:00Rome Fiumicino AirportRome Fiumicino Airport16:00Prague AirportPrague Airport - T1/20EconomyA Flight from Smartwings goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 05/06/2026 14:00:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 05/06/2026 16:00:00. 50 Economy ticket for £75 per person are available. Travel duration is 2h 0m
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FlixBus20h 50m017:05RomeTiburtina Bus Station13:55PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 05/06/2026 17:05:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 06/06/2026 13:55:00. 50 Economy ticket for £84 per person are available. Travel duration is 20h 50m
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FlixBus20h 40m017:05RomeTiburtina Bus Station13:45PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 05/06/2026 17:05:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 06/06/2026 13:45:00. 50 Economy ticket for £84 per person are available. Travel duration is 20h 40m
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FlixBus24h 25m013:05RomeAnagnina Bus Station13:30PragueRoztyly0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 05/06/2026 13:05:00 to Roztyly, Prague (Czech Republic) arriving at 06/06/2026 13:30:00. 50 Economy ticket for £84 per person are available. Travel duration is 24h 25m
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FlixBus22h 15m007:30RomeTiburtina Bus Station05:45PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 05/06/2026 07:30:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 06/06/2026 05:45:00. 50 Economy ticket for £86 per person are available. Travel duration is 22h 15m
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FlixBus25h 25m017:05RomeTiburtina Bus Station18:30PragueZličín0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 05/06/2026 17:05:00 to Zličín, Prague (Czech Republic) arriving at 06/06/2026 18:30:00. 50 Economy ticket for £86 per person are available. Travel duration is 25h 25m
Cheapest Flights Friday
Cheapest Buses Friday
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Wizz Air1h 55m006:45Rome Fiumicino AirportRome Fiumicino Airport08:40Prague AirportPrague Airport - T1/20EconomyA Flight from Wizz Air goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 06/06/2026 06:45:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 06/06/2026 08:40:00. 50 Economy ticket for £28 per person are available. Travel duration is 1h 55m
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ITA Airways13h 30m019:00Rome Fiumicino AirportRome Fiumicino Airport08:30Prague AirportPrague Airport0EconomyA Flight from ITA Airways goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 06/06/2026 19:00:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 07/06/2026 08:30:00. 50 Economy ticket for £91 per person are available. Travel duration is 13h 30m
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Vueling Airlines27h 10m010:30Rome Fiumicino AirportRome Fiumicino Airport13:40Prague AirportPrague Airport0EconomyA Flight from Vueling Airlines goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 06/06/2026 10:30:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 07/06/2026 13:40:00. 50 Economy ticket for £110 per person are available. Travel duration is 27h 10m
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Smartwings2h 0m014:00Rome Fiumicino AirportRome Fiumicino Airport16:00Prague AirportPrague Airport0EconomyA Flight from Smartwings goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 06/06/2026 14:00:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 06/06/2026 16:00:00. 50 Economy ticket for £112 per person are available. Travel duration is 2h 0m
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Transavia France9h 20m012:25Rome Fiumicino AirportRome Fiumicino Airport21:45Prague AirportPrague Airport0EconomyA Flight from Transavia France goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 06/06/2026 12:25:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 06/06/2026 21:45:00. 50 Economy ticket for £139 per person are available. Travel duration is 9h 20m
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FlixBus25h 25m017:05RomeTiburtina Bus Station18:30PragueZličín0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 06/06/2026 17:05:00 to Zličín, Prague (Czech Republic) arriving at 07/06/2026 18:30:00. 50 Economy ticket for £83 per person are available. Travel duration is 25h 25m
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FlixBus23h 25m017:05RomeTiburtina Bus Station16:30PragueRoztyly0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 06/06/2026 17:05:00 to Roztyly, Prague (Czech Republic) arriving at 07/06/2026 16:30:00. 50 Economy ticket for £83 per person are available. Travel duration is 23h 25m
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FlixBus20h 50m017:05RomeTiburtina Bus Station13:55PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 06/06/2026 17:05:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 07/06/2026 13:55:00. 50 Economy ticket for £84 per person are available. Travel duration is 20h 50m
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FlixBus20h 40m017:05RomeTiburtina Bus Station13:45PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 06/06/2026 17:05:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 07/06/2026 13:45:00. 50 Economy ticket for £84 per person are available. Travel duration is 20h 40m
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FlixBus24h 25m013:05RomeAnagnina Bus Station13:30PragueRoztyly0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 06/06/2026 13:05:00 to Roztyly, Prague (Czech Republic) arriving at 07/06/2026 13:30:00. 50 Economy ticket for £84 per person are available. Travel duration is 24h 25m
Cheapest Flights Saturday
Cheapest Buses Saturday
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Wizz Air21h 0m018:00Rome Fiumicino AirportRome Fiumicino Airport15:00Prague AirportPrague Airport - T1/20EconomyA Flight from Wizz Air goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 07/06/2026 18:00:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 08/06/2026 15:00:00. 50 Economy ticket for £32 per person are available. Travel duration is 21h 0m
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Ryanair15h 30m006:35Rome Ciampino AirportRome Ciampino Airport22:05Prague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 07/06/2026 06:35:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 07/06/2026 22:05:00. 50 Economy ticket for £50 per person are available. Travel duration is 15h 30m
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Skyscanner7h 40m013:00Rome Ciampino AirportRome Ciampino Airport20:40Prague AirportPrague Airport - T1/20EconomyA Flight from Skyscanner goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 07/06/2026 13:00:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 07/06/2026 20:40:00. 50 Economy ticket for £53 per person are available. Travel duration is 7h 40m
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LC Perú1h 55m006:45Rome Fiumicino AirportRome Fiumicino Airport08:40Prague AirportPrague Airport - T1/20EconomyA Flight from LC Perú goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 07/06/2026 06:45:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 07/06/2026 08:40:00. 50 Economy ticket for £54 per person are available. Travel duration is 1h 55m
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Buzz9h 50m007:40Rome Ciampino AirportRome Ciampino Airport17:30Prague AirportPrague Airport - T1/20EconomyA Flight from Buzz goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 07/06/2026 07:40:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 07/06/2026 17:30:00. 50 Economy ticket for £77 per person are available. Travel duration is 9h 50m
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FlixBus27h 40m023:35RomeAnagnina Bus Station03:15PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 07/06/2026 23:35:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 09/06/2026 03:15:00. 50 Economy ticket for £73 per person are available. Travel duration is 27h 40m
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FlixBus26h 45m010:45Rome Ciampino AirportRome Ciampino Airport13:30PragueRoztyly0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 07/06/2026 10:45:00 to Roztyly, Prague (Czech Republic) arriving at 08/06/2026 13:30:00. 50 Economy ticket for £83 per person are available. Travel duration is 26h 45m
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FlixBus24h 25m013:05RomeAnagnina Bus Station13:30PragueRoztyly0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 07/06/2026 13:05:00 to Roztyly, Prague (Czech Republic) arriving at 08/06/2026 13:30:00. 50 Economy ticket for £88 per person are available. Travel duration is 24h 25m
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FlixBus25h 0m012:20RomeTiburtina Bus Station13:20PragueRoztyly0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 07/06/2026 12:20:00 to Roztyly, Prague (Czech Republic) arriving at 08/06/2026 13:20:00. 50 Economy ticket for £91 per person are available. Travel duration is 25h 0m
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FlixBus24h 35m012:45RomeAnagnina Bus Station13:20PragueRoztyly0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 07/06/2026 12:45:00 to Roztyly, Prague (Czech Republic) arriving at 08/06/2026 13:20:00. 50 Economy ticket for £95 per person are available. Travel duration is 24h 35m
Cheapest Flights Sunday
Cheapest Buses Sunday
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Wizz Air1h 55m006:45Rome Fiumicino AirportRome Fiumicino Airport08:40Prague AirportPrague Airport - T1/20EconomyA Flight from Wizz Air goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 08/06/2026 06:45:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 08/06/2026 08:40:00. 50 Economy ticket for £26 per person are available. Travel duration is 1h 55m
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LC Perú1h 55m006:45Rome Fiumicino AirportRome Fiumicino Airport08:40Prague AirportPrague Airport - T1/20EconomyA Flight from LC Perú goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 08/06/2026 06:45:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 08/06/2026 08:40:00. 50 Economy ticket for £27 per person are available. Travel duration is 1h 55m
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Skyscanner1h 50m011:15Rome Ciampino AirportRome Ciampino Airport13:05Prague AirportPrague Airport - T1/20EconomyA Flight from Skyscanner goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 08/06/2026 11:15:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 08/06/2026 13:05:00. 50 Economy ticket for £37 per person are available. Travel duration is 1h 50m
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Ryanair1h 50m011:15Rome Ciampino AirportRome Ciampino Airport13:05Prague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 08/06/2026 11:15:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 08/06/2026 13:05:00. 50 Economy ticket for £38 per person are available. Travel duration is 1h 50m
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Vueling Airlines11h 55m021:55Rome Fiumicino AirportRome Fiumicino Airport09:50Prague AirportPrague Airport - T1/20EconomyA Flight from Vueling Airlines goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 08/06/2026 21:55:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 09/06/2026 09:50:00. 50 Economy ticket for £60 per person are available. Travel duration is 11h 55m
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FlixBus22h 40m010:45Rome Ciampino AirportRome Ciampino Airport09:25PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 08/06/2026 10:45:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 09/06/2026 09:25:00. 50 Economy ticket for £65 per person are available. Travel duration is 22h 40m
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FlixBus27h 40m023:35RomeAnagnina Bus Station03:15PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 08/06/2026 23:35:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 10/06/2026 03:15:00. 50 Economy ticket for £67 per person are available. Travel duration is 27h 40m
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FlixBus22h 45m021:20RomeTiburtina Bus Station20:05PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 08/06/2026 21:20:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 09/06/2026 20:05:00. 50 Economy ticket for £69 per person are available. Travel duration is 22h 45m
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FlixBus23h 20m021:00RomeTiburtina Bus Station20:20PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 08/06/2026 21:00:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 09/06/2026 20:20:00. 50 Economy ticket for £69 per person are available. Travel duration is 23h 20m
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FlixBus22h 55m021:20RomeTiburtina Bus Station20:15PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 08/06/2026 21:20:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 09/06/2026 20:15:00. 50 Economy ticket for £69 per person are available. Travel duration is 22h 55m
Cheapest Flights Monday
Cheapest Buses Monday
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Wizz Air1h 55m006:45Rome Fiumicino AirportRome Fiumicino Airport08:40Prague AirportPrague Airport - T1/20EconomyA Flight from Wizz Air goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 09/06/2026 06:45:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 09/06/2026 08:40:00. 50 Economy ticket for £10 per person are available. Travel duration is 1h 55m
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LC Perú1h 55m006:45Rome Fiumicino AirportRome Fiumicino Airport08:40Prague AirportPrague Airport - T1/20EconomyA Flight from LC Perú goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 09/06/2026 06:45:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 09/06/2026 08:40:00. 50 Economy ticket for £11 per person are available. Travel duration is 1h 55m
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Skyscanner1h 50m006:05Rome Ciampino AirportRome Ciampino Airport07:55Prague AirportPrague Airport - T1/20EconomyA Flight from Skyscanner goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 09/06/2026 06:05:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 09/06/2026 07:55:00. 50 Economy ticket for £21 per person are available. Travel duration is 1h 50m
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Ryanair1h 50m006:05Rome Ciampino AirportRome Ciampino Airport07:55Prague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 09/06/2026 06:05:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 09/06/2026 07:55:00. 50 Economy ticket for £23 per person are available. Travel duration is 1h 50m
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Smartwings2h 0m014:00Rome Fiumicino AirportRome Fiumicino Airport16:00Prague AirportPrague Airport - T1/20EconomyA Flight from Smartwings goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 09/06/2026 14:00:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 09/06/2026 16:00:00. 50 Economy ticket for £76 per person are available. Travel duration is 2h 0m
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FlixBus26h 55m021:00RomeTiburtina Bus Station23:55PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 09/06/2026 21:00:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 10/06/2026 23:55:00. 50 Economy ticket for £58 per person are available. Travel duration is 26h 55m
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FlixBus22h 45m021:20RomeTiburtina Bus Station20:05PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 09/06/2026 21:20:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 10/06/2026 20:05:00. 50 Economy ticket for £58 per person are available. Travel duration is 22h 45m
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FlixBus24h 35m017:00RomeTiburtina Bus Station17:35PragueHradčanská0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 09/06/2026 17:00:00 to Hradčanská, Prague (Czech Republic) arriving at 10/06/2026 17:35:00. 50 Economy ticket for £58 per person are available. Travel duration is 24h 35m
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FlixBus22h 55m021:20RomeTiburtina Bus Station20:15PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 09/06/2026 21:20:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 10/06/2026 20:15:00. 50 Economy ticket for £58 per person are available. Travel duration is 22h 55m
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FlixBus25h 45m017:25RomeAnagnina Bus Station19:10PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 09/06/2026 17:25:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 10/06/2026 19:10:00. 50 Economy ticket for £58 per person are available. Travel duration is 25h 45m
Cheapest Flights Tuesday
Cheapest Buses Tuesday
What are the fastest trips from Rome to Prague?
You can get to Prague from Rome in just 1h 50m with a Flight from Skyscanner. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
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Skyscanner1h 50m006:00Rome Ciampino AirportRome Ciampino Airport07:50Prague AirportPrague Airport - T1/20EconomyA Flight from Skyscanner goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 03/06/2026 06:00:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 03/06/2026 07:50:00. 50 Economy ticket for £17 per person are available. Travel duration is 1h 50m
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Ryanair1h 50m006:00Rome Ciampino AirportRome Ciampino Airport07:50Prague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 03/06/2026 06:00:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 03/06/2026 07:50:00. 50 Economy ticket for £18 per person are available. Travel duration is 1h 50m
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LC Perú1h 55m006:45Rome Fiumicino AirportRome Fiumicino Airport08:40Prague AirportPrague Airport - T1/20EconomyA Flight from LC Perú goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 03/06/2026 06:45:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 03/06/2026 08:40:00. 50 Economy ticket for £29 per person are available. Travel duration is 1h 55m
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Condor4h 50m011:10Rome Fiumicino AirportRome Fiumicino Airport16:00Prague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 03/06/2026 11:10:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 03/06/2026 16:00:00. 50 Economy ticket for £68 per person are available. Travel duration is 4h 50m
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Buzz7h 45m010:40Rome Ciampino AirportRome Ciampino Airport18:25Prague AirportPrague Airport - T1/20EconomyA Flight from Buzz goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 03/06/2026 10:40:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 03/06/2026 18:25:00. 50 Economy ticket for £41 per person are available. Travel duration is 7h 45m
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FlixBus20h 25m022:55RomeTiburtina Bus Station19:20PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 03/06/2026 22:55:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 04/06/2026 19:20:00. 50 Economy ticket for £96 per person are available. Travel duration is 20h 25m
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FlixBus20h 35m022:55RomeTiburtina Bus Station19:30PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 03/06/2026 22:55:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 04/06/2026 19:30:00. 50 Economy ticket for £96 per person are available. Travel duration is 20h 35m
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FlixBus24h 0m022:55RomeTiburtina Bus Station22:55PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 03/06/2026 22:55:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 04/06/2026 22:55:00. 50 Economy ticket for £95 per person are available. Travel duration is 24h 0m
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FlixBus25h 0m012:20RomeTiburtina Bus Station13:20PragueRoztyly0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 03/06/2026 12:20:00 to Roztyly, Prague (Czech Republic) arriving at 04/06/2026 13:20:00. 50 Economy ticket for £97 per person are available. Travel duration is 25h 0m
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FlixBus26h 55m021:00RomeTiburtina Bus Station23:55PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 03/06/2026 21:00:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 04/06/2026 23:55:00. 50 Economy ticket for £95 per person are available. Travel duration is 26h 55m
Fastest Flights Wednesday
Fastest Buses Wednesday
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Skyscanner1h 50m006:00Rome Ciampino AirportRome Ciampino Airport07:50Prague AirportPrague Airport - T1/20EconomyA Flight from Skyscanner goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 04/06/2026 06:00:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 04/06/2026 07:50:00. 50 Economy ticket for £17 per person are available. Travel duration is 1h 50m
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Ryanair1h 50m006:00Rome Ciampino AirportRome Ciampino Airport07:50Prague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 04/06/2026 06:00:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 04/06/2026 07:50:00. 50 Economy ticket for £18 per person are available. Travel duration is 1h 50m
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LC Perú1h 55m006:45Rome Fiumicino AirportRome Fiumicino Airport08:40Prague AirportPrague Airport - T1/20EconomyA Flight from LC Perú goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 04/06/2026 06:45:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 04/06/2026 08:40:00. 50 Economy ticket for £26 per person are available. Travel duration is 1h 55m
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Wizz Air9h 50m021:10Rome Fiumicino AirportRome Fiumicino Airport07:00Prague AirportPrague Airport - T1/20EconomyA Flight from Wizz Air goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 04/06/2026 21:10:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 05/06/2026 07:00:00. 50 Economy ticket for £57 per person are available. Travel duration is 9h 50m
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Buzz14h 25m016:35Rome Ciampino AirportRome Ciampino Airport07:00Prague AirportPrague Airport - T1/20EconomyA Flight from Buzz goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 04/06/2026 16:35:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 05/06/2026 07:00:00. 50 Economy ticket for £38 per person are available. Travel duration is 14h 25m
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FlixBus20h 40m017:05RomeTiburtina Bus Station13:45PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 04/06/2026 17:05:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 05/06/2026 13:45:00. 50 Economy ticket for £79 per person are available. Travel duration is 20h 40m
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FlixBus20h 50m017:05RomeTiburtina Bus Station13:55PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 04/06/2026 17:05:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 05/06/2026 13:55:00. 50 Economy ticket for £79 per person are available. Travel duration is 20h 50m
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FlixBus22h 40m010:45Rome Ciampino AirportRome Ciampino Airport09:25PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 04/06/2026 10:45:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 05/06/2026 09:25:00. 50 Economy ticket for £76 per person are available. Travel duration is 22h 40m
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FlixBus25h 25m012:20RomeTiburtina Bus Station13:45PragueČerný Most0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 04/06/2026 12:20:00 to Černý Most, Prague (Czech Republic) arriving at 05/06/2026 13:45:00. 50 Economy ticket for £79 per person are available. Travel duration is 25h 25m
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FlixBus27h 40m023:35RomeAnagnina Bus Station03:15PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 04/06/2026 23:35:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 06/06/2026 03:15:00. 50 Economy ticket for £79 per person are available. Travel duration is 27h 40m
Fastest Flights Thursday
Fastest Buses Thursday
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Skyscanner1h 50m017:30Rome Ciampino AirportRome Ciampino Airport19:20Prague AirportPrague Airport - T1/20EconomyA Flight from Skyscanner goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 05/06/2026 17:30:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 05/06/2026 19:20:00. 50 Economy ticket for £25 per person are available. Travel duration is 1h 50m
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Ryanair1h 50m017:30Rome Ciampino AirportRome Ciampino Airport19:20Prague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 05/06/2026 17:30:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 05/06/2026 19:20:00. 50 Economy ticket for £30 per person are available. Travel duration is 1h 50m
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LC Perú1h 55m006:45Rome Fiumicino AirportRome Fiumicino Airport08:40Prague AirportPrague Airport - T1/20EconomyA Flight from LC Perú goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 05/06/2026 06:45:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 05/06/2026 08:40:00. 50 Economy ticket for £25 per person are available. Travel duration is 1h 55m
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Wizz Air1h 55m006:45Rome Fiumicino AirportRome Fiumicino Airport08:40Prague AirportPrague Airport - T1/20EconomyA Flight from Wizz Air goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 05/06/2026 06:45:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 05/06/2026 08:40:00. 50 Economy ticket for £25 per person are available. Travel duration is 1h 55m
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Smartwings2h 0m014:00Rome Fiumicino AirportRome Fiumicino Airport16:00Prague AirportPrague Airport - T1/20EconomyA Flight from Smartwings goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 05/06/2026 14:00:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 05/06/2026 16:00:00. 50 Economy ticket for £75 per person are available. Travel duration is 2h 0m
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FlixBus20h 40m017:05RomeTiburtina Bus Station13:45PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 05/06/2026 17:05:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 06/06/2026 13:45:00. 50 Economy ticket for £84 per person are available. Travel duration is 20h 40m
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FlixBus20h 50m017:05RomeTiburtina Bus Station13:55PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 05/06/2026 17:05:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 06/06/2026 13:55:00. 50 Economy ticket for £84 per person are available. Travel duration is 20h 50m
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FlixBus22h 15m007:30RomeTiburtina Bus Station05:45PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 05/06/2026 07:30:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 06/06/2026 05:45:00. 50 Economy ticket for £86 per person are available. Travel duration is 22h 15m
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FlixBus24h 25m013:05RomeAnagnina Bus Station13:30PragueRoztyly0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 05/06/2026 13:05:00 to Roztyly, Prague (Czech Republic) arriving at 06/06/2026 13:30:00. 50 Economy ticket for £84 per person are available. Travel duration is 24h 25m
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FlixBus25h 25m017:05RomeTiburtina Bus Station18:30PragueZličín0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 05/06/2026 17:05:00 to Zličín, Prague (Czech Republic) arriving at 06/06/2026 18:30:00. 50 Economy ticket for £86 per person are available. Travel duration is 25h 25m
Fastest Flights Friday
Fastest Buses Friday
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Wizz Air1h 55m006:45Rome Fiumicino AirportRome Fiumicino Airport08:40Prague AirportPrague Airport - T1/20EconomyA Flight from Wizz Air goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 06/06/2026 06:45:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 06/06/2026 08:40:00. 50 Economy ticket for £28 per person are available. Travel duration is 1h 55m
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Smartwings2h 0m014:00Rome Fiumicino AirportRome Fiumicino Airport16:00Prague AirportPrague Airport0EconomyA Flight from Smartwings goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 06/06/2026 14:00:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 06/06/2026 16:00:00. 50 Economy ticket for £112 per person are available. Travel duration is 2h 0m
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Transavia France9h 20m012:25Rome Fiumicino AirportRome Fiumicino Airport21:45Prague AirportPrague Airport0EconomyA Flight from Transavia France goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 06/06/2026 12:25:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 06/06/2026 21:45:00. 50 Economy ticket for £139 per person are available. Travel duration is 9h 20m
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ITA Airways13h 30m019:00Rome Fiumicino AirportRome Fiumicino Airport08:30Prague AirportPrague Airport0EconomyA Flight from ITA Airways goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 06/06/2026 19:00:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 07/06/2026 08:30:00. 50 Economy ticket for £91 per person are available. Travel duration is 13h 30m
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Vueling Airlines27h 10m010:30Rome Fiumicino AirportRome Fiumicino Airport13:40Prague AirportPrague Airport0EconomyA Flight from Vueling Airlines goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 06/06/2026 10:30:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 07/06/2026 13:40:00. 50 Economy ticket for £110 per person are available. Travel duration is 27h 10m
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FlixBus20h 40m017:05RomeTiburtina Bus Station13:45PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 06/06/2026 17:05:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 07/06/2026 13:45:00. 50 Economy ticket for £84 per person are available. Travel duration is 20h 40m
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FlixBus20h 50m017:05RomeTiburtina Bus Station13:55PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 06/06/2026 17:05:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 07/06/2026 13:55:00. 50 Economy ticket for £84 per person are available. Travel duration is 20h 50m
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FlixBus23h 25m017:05RomeTiburtina Bus Station16:30PragueRoztyly0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 06/06/2026 17:05:00 to Roztyly, Prague (Czech Republic) arriving at 07/06/2026 16:30:00. 50 Economy ticket for £83 per person are available. Travel duration is 23h 25m
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FlixBus24h 25m013:05RomeAnagnina Bus Station13:30PragueRoztyly0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 06/06/2026 13:05:00 to Roztyly, Prague (Czech Republic) arriving at 07/06/2026 13:30:00. 50 Economy ticket for £84 per person are available. Travel duration is 24h 25m
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FlixBus25h 25m017:05RomeTiburtina Bus Station18:30PragueZličín0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 06/06/2026 17:05:00 to Zličín, Prague (Czech Republic) arriving at 07/06/2026 18:30:00. 50 Economy ticket for £83 per person are available. Travel duration is 25h 25m
Fastest Flights Saturday
Fastest Buses Saturday
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LC Perú1h 55m006:45Rome Fiumicino AirportRome Fiumicino Airport08:40Prague AirportPrague Airport - T1/20EconomyA Flight from LC Perú goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 07/06/2026 06:45:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 07/06/2026 08:40:00. 50 Economy ticket for £54 per person are available. Travel duration is 1h 55m
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Skyscanner7h 40m013:00Rome Ciampino AirportRome Ciampino Airport20:40Prague AirportPrague Airport - T1/20EconomyA Flight from Skyscanner goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 07/06/2026 13:00:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 07/06/2026 20:40:00. 50 Economy ticket for £53 per person are available. Travel duration is 7h 40m
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Buzz9h 50m007:40Rome Ciampino AirportRome Ciampino Airport17:30Prague AirportPrague Airport - T1/20EconomyA Flight from Buzz goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 07/06/2026 07:40:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 07/06/2026 17:30:00. 50 Economy ticket for £77 per person are available. Travel duration is 9h 50m
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Ryanair15h 30m006:35Rome Ciampino AirportRome Ciampino Airport22:05Prague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 07/06/2026 06:35:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 07/06/2026 22:05:00. 50 Economy ticket for £50 per person are available. Travel duration is 15h 30m
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Wizz Air21h 0m018:00Rome Fiumicino AirportRome Fiumicino Airport15:00Prague AirportPrague Airport - T1/20EconomyA Flight from Wizz Air goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 07/06/2026 18:00:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 08/06/2026 15:00:00. 50 Economy ticket for £32 per person are available. Travel duration is 21h 0m
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FlixBus24h 25m013:05RomeAnagnina Bus Station13:30PragueRoztyly0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 07/06/2026 13:05:00 to Roztyly, Prague (Czech Republic) arriving at 08/06/2026 13:30:00. 50 Economy ticket for £88 per person are available. Travel duration is 24h 25m
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FlixBus24h 35m012:45RomeAnagnina Bus Station13:20PragueRoztyly0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 07/06/2026 12:45:00 to Roztyly, Prague (Czech Republic) arriving at 08/06/2026 13:20:00. 50 Economy ticket for £95 per person are available. Travel duration is 24h 35m
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FlixBus25h 0m012:20RomeTiburtina Bus Station13:20PragueRoztyly0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 07/06/2026 12:20:00 to Roztyly, Prague (Czech Republic) arriving at 08/06/2026 13:20:00. 50 Economy ticket for £91 per person are available. Travel duration is 25h 0m
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FlixBus26h 45m010:45Rome Ciampino AirportRome Ciampino Airport13:30PragueRoztyly0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 07/06/2026 10:45:00 to Roztyly, Prague (Czech Republic) arriving at 08/06/2026 13:30:00. 50 Economy ticket for £83 per person are available. Travel duration is 26h 45m
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FlixBus27h 40m023:35RomeAnagnina Bus Station03:15PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 07/06/2026 23:35:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 09/06/2026 03:15:00. 50 Economy ticket for £73 per person are available. Travel duration is 27h 40m
Fastest Flights Sunday
Fastest Buses Sunday
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Skyscanner1h 50m011:15Rome Ciampino AirportRome Ciampino Airport13:05Prague AirportPrague Airport - T1/20EconomyA Flight from Skyscanner goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 08/06/2026 11:15:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 08/06/2026 13:05:00. 50 Economy ticket for £37 per person are available. Travel duration is 1h 50m
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Ryanair1h 50m011:15Rome Ciampino AirportRome Ciampino Airport13:05Prague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 08/06/2026 11:15:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 08/06/2026 13:05:00. 50 Economy ticket for £38 per person are available. Travel duration is 1h 50m
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Wizz Air1h 55m006:45Rome Fiumicino AirportRome Fiumicino Airport08:40Prague AirportPrague Airport - T1/20EconomyA Flight from Wizz Air goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 08/06/2026 06:45:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 08/06/2026 08:40:00. 50 Economy ticket for £26 per person are available. Travel duration is 1h 55m
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LC Perú1h 55m006:45Rome Fiumicino AirportRome Fiumicino Airport08:40Prague AirportPrague Airport - T1/20EconomyA Flight from LC Perú goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 08/06/2026 06:45:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 08/06/2026 08:40:00. 50 Economy ticket for £27 per person are available. Travel duration is 1h 55m
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Vueling Airlines11h 55m021:55Rome Fiumicino AirportRome Fiumicino Airport09:50Prague AirportPrague Airport - T1/20EconomyA Flight from Vueling Airlines goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 08/06/2026 21:55:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 09/06/2026 09:50:00. 50 Economy ticket for £60 per person are available. Travel duration is 11h 55m
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FlixBus22h 40m010:45Rome Ciampino AirportRome Ciampino Airport09:25PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 08/06/2026 10:45:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 09/06/2026 09:25:00. 50 Economy ticket for £65 per person are available. Travel duration is 22h 40m
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FlixBus22h 45m021:20RomeTiburtina Bus Station20:05PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 08/06/2026 21:20:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 09/06/2026 20:05:00. 50 Economy ticket for £69 per person are available. Travel duration is 22h 45m
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FlixBus22h 55m021:20RomeTiburtina Bus Station20:15PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 08/06/2026 21:20:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 09/06/2026 20:15:00. 50 Economy ticket for £69 per person are available. Travel duration is 22h 55m
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FlixBus23h 20m021:00RomeTiburtina Bus Station20:20PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 08/06/2026 21:00:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 09/06/2026 20:20:00. 50 Economy ticket for £69 per person are available. Travel duration is 23h 20m
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FlixBus27h 40m023:35RomeAnagnina Bus Station03:15PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 08/06/2026 23:35:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 10/06/2026 03:15:00. 50 Economy ticket for £67 per person are available. Travel duration is 27h 40m
Fastest Flights Monday
Fastest Buses Monday
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Skyscanner1h 50m006:05Rome Ciampino AirportRome Ciampino Airport07:55Prague AirportPrague Airport - T1/20EconomyA Flight from Skyscanner goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 09/06/2026 06:05:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 09/06/2026 07:55:00. 50 Economy ticket for £21 per person are available. Travel duration is 1h 50m
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Ryanair1h 50m006:05Rome Ciampino AirportRome Ciampino Airport07:55Prague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 09/06/2026 06:05:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 09/06/2026 07:55:00. 50 Economy ticket for £23 per person are available. Travel duration is 1h 50m
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Wizz Air1h 55m006:45Rome Fiumicino AirportRome Fiumicino Airport08:40Prague AirportPrague Airport - T1/20EconomyA Flight from Wizz Air goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 09/06/2026 06:45:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 09/06/2026 08:40:00. 50 Economy ticket for £10 per person are available. Travel duration is 1h 55m
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LC Perú1h 55m006:45Rome Fiumicino AirportRome Fiumicino Airport08:40Prague AirportPrague Airport - T1/20EconomyA Flight from LC Perú goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 09/06/2026 06:45:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 09/06/2026 08:40:00. 50 Economy ticket for £11 per person are available. Travel duration is 1h 55m
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Smartwings2h 0m014:00Rome Fiumicino AirportRome Fiumicino Airport16:00Prague AirportPrague Airport - T1/20EconomyA Flight from Smartwings goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 09/06/2026 14:00:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 09/06/2026 16:00:00. 50 Economy ticket for £76 per person are available. Travel duration is 2h 0m
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FlixBus22h 45m021:20RomeTiburtina Bus Station20:05PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 09/06/2026 21:20:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 10/06/2026 20:05:00. 50 Economy ticket for £58 per person are available. Travel duration is 22h 45m
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FlixBus22h 55m021:20RomeTiburtina Bus Station20:15PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 09/06/2026 21:20:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 10/06/2026 20:15:00. 50 Economy ticket for £58 per person are available. Travel duration is 22h 55m
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FlixBus24h 35m017:00RomeTiburtina Bus Station17:35PragueHradčanská0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 09/06/2026 17:00:00 to Hradčanská, Prague (Czech Republic) arriving at 10/06/2026 17:35:00. 50 Economy ticket for £58 per person are available. Travel duration is 24h 35m
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FlixBus25h 45m017:25RomeAnagnina Bus Station19:10PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 09/06/2026 17:25:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 10/06/2026 19:10:00. 50 Economy ticket for £58 per person are available. Travel duration is 25h 45m
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FlixBus26h 55m021:00RomeTiburtina Bus Station23:55PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 09/06/2026 21:00:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 10/06/2026 23:55:00. 50 Economy ticket for £58 per person are available. Travel duration is 26h 55m
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Here you will find all operators and timetables for a
Bus from Rome to Prague
What are the most popular stations in Rome and Prague?
In Rome, you will usually depart from Termini Bus Station, Ostiense Train Station or Termini Central Station, while in Prague you will be arriving at Wilsonova Coach Station, ÚAN Florenc or Černý Most, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Prague from Rome? With 10 connections between 1 Flight and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Rome and Prague, you can pay as low as £10 with a Flight from Wizz Air.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Skyscanner: you will get to Prague in just 1h 50m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Rome and Prague are FlixBus, Skyscanner and Ryanair, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Rome and Prague is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Settebagni or to Horoměřice, and look at flights from Rome Ciampino Airport, and landing at Prague Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Rome to Prague?
The most popular companies between Rome and Prague, are FlixBus, Skyscanner and Ryanair. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: FlixBus
Airlines: Skyscanner, Ryanair, LC Perú and 7 more.
All you need to know when you travel from Rome to Prague
Check all information on comfort and services on all modes of transports from Rome to Prague. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Rome to Prague
How can I reach Prague from Rome?
Every day, there are on average 10 connections between Flight and Bus, with which you can get to Prague from Rome.
How far is Prague from Rome?
The distance between Rome and Prague is 921.0 km.
What is the most ecofriendly mode of transport between Rome and Prague?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 25 kgs of CO2, a train 32 kgs, a car 157 kgs, and a flight 227 kgs.
What is the cheapest mode of transport from Rome to Prague?
You can get to Prague with just £10 by taking a Flight from Wizz Air.
What is the fastest way to get from Rome to Prague?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Prague in just 1h 50m with a Flight from Skyscanner.
More routes to Rome and to Prague
Looking for more options? Here you can see the most popular routes to Rome and to Prague. Simply click on a connection, and you’ll find all the details about the route!
