Bus and Coach from Pisa to Milan: Compare all prices

Compare all timetables for the bus from Pisa to Milan

Here is a selection of the cheapest bus trips from the schedule from Pisa to Milan from various bus operators like FlixBus for the next days.

today

£21

tomorrow

£23

Sunday

£25

Monday

£27

Tuesday

Wednesday

£24

Thursday

£17

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	5h 0m	16:45	Pisa	Pietrasantina Bus Station	21:45	Milan	Lampugnano Bus Station	Economy	£21	A Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 05/12/2025 16:45:00 to Lampugnano Bus Station, Milan (Italy) arriving at 05/12/2025 21:45:00. 50 Economy ticket for £21 per person are available. Travel duration is 5h 0m
FlixBus	5h 35m	04:50	Pisa	Pietrasantina Bus Station	10:25	Milan	San Donato Bus Station	Economy	£24	A Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 05/12/2025 04:50:00 to San Donato Bus Station, Milan (Italy) arriving at 05/12/2025 10:25:00. 50 Economy ticket for £24 per person are available. Travel duration is 5h 35m
FlixBus	6h 20m	04:50	Pisa	Pietrasantina Bus Station	11:10	Milan	Lampugnano Bus Station	Economy	£24	A Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 05/12/2025 04:50:00 to Lampugnano Bus Station, Milan (Italy) arriving at 05/12/2025 11:10:00. 50 Economy ticket for £24 per person are available. Travel duration is 6h 20m
FlixBus	5h 15m	06:25	Pisa	Pietrasantina Bus Station	11:40	Milan	San Donato Bus Station	Economy	£25	A Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 05/12/2025 06:25:00 to San Donato Bus Station, Milan (Italy) arriving at 05/12/2025 11:40:00. 50 Economy ticket for £25 per person are available. Travel duration is 5h 15m
FlixBus	6h 50m	18:15	Pisa	Pietrasantina Bus Station	01:05	Milan	Lampugnano Bus Station	Economy	£25	A Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 05/12/2025 18:15:00 to Lampugnano Bus Station, Milan (Italy) arriving at 06/12/2025 01:05:00. 50 Economy ticket for £25 per person are available. Travel duration is 6h 50m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	5h 15m	13:40	Pisa	Pietrasantina Bus Station	18:55	Milan	Lampugnano Bus Station	Economy	£23	A Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 06/12/2025 13:40:00 to Lampugnano Bus Station, Milan (Italy) arriving at 06/12/2025 18:55:00. 50 Economy ticket for £23 per person are available. Travel duration is 5h 15m
FlixBus	5h 0m	16:45	Pisa	Pietrasantina Bus Station	21:45	Milan	Lampugnano Bus Station	Economy	£23	A Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 06/12/2025 16:45:00 to Lampugnano Bus Station, Milan (Italy) arriving at 06/12/2025 21:45:00. 50 Economy ticket for £23 per person are available. Travel duration is 5h 0m
FlixBus	6h 50m	18:15	Pisa	Pietrasantina Bus Station	01:05	Milan	Lampugnano Bus Station	Economy	£23	A Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 06/12/2025 18:15:00 to Lampugnano Bus Station, Milan (Italy) arriving at 07/12/2025 01:05:00. 50 Economy ticket for £23 per person are available. Travel duration is 6h 50m
FlixBus	6h 15m	16:45	Pisa	Pietrasantina Bus Station	23:00	Milan	San Donato Bus Station	Economy	£24	A Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 06/12/2025 16:45:00 to San Donato Bus Station, Milan (Italy) arriving at 06/12/2025 23:00:00. 50 Economy ticket for £24 per person are available. Travel duration is 6h 15m
FlixBus	6h 0m	22:00	Pisa	Pietrasantina Bus Station	04:00	Milan	Lampugnano Bus Station	Economy	£24	A Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 06/12/2025 22:00:00 to Lampugnano Bus Station, Milan (Italy) arriving at 07/12/2025 04:00:00. 50 Economy ticket for £24 per person are available. Travel duration is 6h 0m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	5h 15m	13:40	Pisa	Pietrasantina Bus Station	18:55	Milan	Lampugnano Bus Station	Economy	£25	A Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 07/12/2025 13:40:00 to Lampugnano Bus Station, Milan (Italy) arriving at 07/12/2025 18:55:00. 50 Economy ticket for £25 per person are available. Travel duration is 5h 15m
FlixBus	5h 0m	16:45	Pisa	Pietrasantina Bus Station	21:45	Milan	Lampugnano Bus Station	Economy	£25	A Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 07/12/2025 16:45:00 to Lampugnano Bus Station, Milan (Italy) arriving at 07/12/2025 21:45:00. 50 Economy ticket for £25 per person are available. Travel duration is 5h 0m
FlixBus	5h 15m	06:25	Pisa	Pietrasantina Bus Station	11:40	Milan	San Donato Bus Station	Economy	£27	A Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 07/12/2025 06:25:00 to San Donato Bus Station, Milan (Italy) arriving at 07/12/2025 11:40:00. 50 Economy ticket for £27 per person are available. Travel duration is 5h 15m
FlixBus	6h 50m	18:15	Pisa	Pietrasantina Bus Station	01:05	Milan	Lampugnano Bus Station	Economy	£27	A Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 07/12/2025 18:15:00 to Lampugnano Bus Station, Milan (Italy) arriving at 08/12/2025 01:05:00. 50 Economy ticket for £27 per person are available. Travel duration is 6h 50m
FlixBus	6h 0m	22:00	Pisa	Pietrasantina Bus Station	04:00	Milan	Lampugnano Bus Station	Economy	£27	A Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 07/12/2025 22:00:00 to Lampugnano Bus Station, Milan (Italy) arriving at 08/12/2025 04:00:00. 50 Economy ticket for £27 per person are available. Travel duration is 6h 0m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	5h 15m	13:40	Pisa	Pietrasantina Bus Station	18:55	Milan	Lampugnano Bus Station	Economy	£27	A Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 08/12/2025 13:40:00 to Lampugnano Bus Station, Milan (Italy) arriving at 08/12/2025 18:55:00. 50 Economy ticket for £27 per person are available. Travel duration is 5h 15m
FlixBus	5h 35m	04:50	Pisa	Pietrasantina Bus Station	10:25	Milan	San Donato Bus Station	Economy	£28	A Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 08/12/2025 04:50:00 to San Donato Bus Station, Milan (Italy) arriving at 08/12/2025 10:25:00. 50 Economy ticket for £28 per person are available. Travel duration is 5h 35m
FlixBus	6h 20m	04:50	Pisa	Pietrasantina Bus Station	11:10	Milan	Lampugnano Bus Station	Economy	£28	A Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 08/12/2025 04:50:00 to Lampugnano Bus Station, Milan (Italy) arriving at 08/12/2025 11:10:00. 50 Economy ticket for £28 per person are available. Travel duration is 6h 20m
FlixBus	5h 15m	06:25	Pisa	Pietrasantina Bus Station	11:40	Milan	San Donato Bus Station	Economy	£31	A Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 08/12/2025 06:25:00 to San Donato Bus Station, Milan (Italy) arriving at 08/12/2025 11:40:00. 50 Economy ticket for £31 per person are available. Travel duration is 5h 15m
FlixBus	6h 0m	22:00	Pisa	Pietrasantina Bus Station	04:00	Milan	Lampugnano Bus Station	Economy	£37	A Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 08/12/2025 22:00:00 to Lampugnano Bus Station, Milan (Italy) arriving at 09/12/2025 04:00:00. 50 Economy ticket for £37 per person are available. Travel duration is 6h 0m

Cheapest bus trips Wednesday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	6h 50m	18:15	Pisa	Pietrasantina Bus Station	01:05	Milan	Lampugnano Bus Station		Economy	£24	A Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 10/12/2025 18:15:00 to Lampugnano Bus Station, Milan (Italy) arriving at 11/12/2025 01:05:00. 50 Economy ticket for £24 per person are available. Travel duration is 6h 50m

Did you know that if you travel from Pisa to Milan via La Spezia, you can save more than £10? You can find the corresponding connections below.
- FlixBus
  
  7h 5m
  
  0
  
  23:45
  
  Pisa
  Pietrasantina Bus Station
  
  01:05
  
  La Spezia
  Via Carducci Bus Stop
  
  0
  
  Economy
  
  £6
  
  A Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 11/12/2025 23:45:00 to Via Carducci Bus Stop, La Spezia (Italy) arriving at 12/12/2025 01:05:00. 50 Economy ticket for £6 per person are available. Travel duration is 1h 20m
- Distribusion
  
  4h 5m
  
  0
  
  02:45
  
  La Spezia
  Via Carducci Bus Stop
  
  06:50
  
  Milan
  Lampugnano Bus Station
  
  0
  
  Premium Economy
  
  £8
  
  A Bus from Distribusion goes from Via Carducci Bus Stop, La Spezia (Italy) at 12/12/2025 02:45:00 to Lampugnano Bus Station, Milan (Italy) arriving at 12/12/2025 06:50:00. 50 Premium Economy ticket for £8 per person are available. Travel duration is 4h 5m
Travel time is 0h 15m longer, but you will save £10

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	5h 15m	06:25	Pisa	Pietrasantina Bus Station	11:40	Milan	San Donato Bus Station	Economy	£17	A Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 11/12/2025 06:25:00 to San Donato Bus Station, Milan (Italy) arriving at 11/12/2025 11:40:00. 50 Economy ticket for £17 per person are available. Travel duration is 5h 15m
FlixBus	6h 15m	16:45	Pisa	Pietrasantina Bus Station	23:00	Milan	San Donato Bus Station	Economy	£17	A Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 11/12/2025 16:45:00 to San Donato Bus Station, Milan (Italy) arriving at 11/12/2025 23:00:00. 50 Economy ticket for £17 per person are available. Travel duration is 6h 15m
FlixBus	6h 50m	18:15	Pisa	Pietrasantina Bus Station	01:05	Milan	Lampugnano Bus Station	Economy	£17	A Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 11/12/2025 18:15:00 to Lampugnano Bus Station, Milan (Italy) arriving at 12/12/2025 01:05:00. 50 Economy ticket for £17 per person are available. Travel duration is 6h 50m
FlixBus	6h 0m	22:00	Pisa	Pietrasantina Bus Station	04:00	Milan	Lampugnano Bus Station	Economy	£17	A Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 11/12/2025 22:00:00 to Lampugnano Bus Station, Milan (Italy) arriving at 12/12/2025 04:00:00. 50 Economy ticket for £17 per person are available. Travel duration is 6h 0m
FlixBus	5h 15m	13:40	Pisa	Pietrasantina Bus Station	18:55	Milan	Lampugnano Bus Station	Economy	£18	A Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 11/12/2025 13:40:00 to Lampugnano Bus Station, Milan (Italy) arriving at 11/12/2025 18:55:00. 50 Economy ticket for £18 per person are available. Travel duration is 5h 15m

Did you know that if you travel from Pisa to Milan via La Spezia, you can save more than £3? You can find the corresponding connections below.
- FlixBus
  
  7h 5m
  
  0
  
  23:45
  
  Pisa
  Pietrasantina Bus Station
  
  01:05
  
  La Spezia
  Via Carducci Bus Stop
  
  0
  
  Economy
  
  £6
  
  A Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 11/12/2025 23:45:00 to Via Carducci Bus Stop, La Spezia (Italy) arriving at 12/12/2025 01:05:00. 50 Economy ticket for £6 per person are available. Travel duration is 1h 20m
- Distribusion
  
  4h 5m
  
  0
  
  02:45
  
  La Spezia
  Via Carducci Bus Stop
  
  06:50
  
  Milan
  Lampugnano Bus Station
  
  0
  
  Premium Economy
  
  £8
  
  A Bus from Distribusion goes from Via Carducci Bus Stop, La Spezia (Italy) at 12/12/2025 02:45:00 to Lampugnano Bus Station, Milan (Italy) arriving at 12/12/2025 06:50:00. 50 Premium Economy ticket for £8 per person are available. Travel duration is 4h 5m
Travel time is 1h 50m longer, but you will save £3

Best Price Offer: The price for the cheapest coach from Pisa to Milan is £16 on 03/12/2025. Flexible travellers save on ticket prices.

Frequency of bus connections between Pisa and Milan

See here how frequent the connections between Pisa and Milan are, during different times and days of the week.

Friday is the busiest day, with more than 8 daily coaches from Pisa to Milan. Wednesday has instead the fewest connections, with only 1 daily coaches between Pisa and Milan.

The busiest time of the day is the Afternoon, with 15 coaches from Pisa to Milan, while Morning sees the fewest connections between Pisa and Milan, with 5 offers.

Facts about coaches from Pisa to Milan

Compare all providers like FlixBus that travel 6 times every day by bus from Pisa to Milan in one click! Book your bus ticket from Pisa to Milan starting from £16!

Cheapest Bus	£16
Fastest Bus	5h 0m
Earliest Coach	04:50
Latest Coach	22:00
Daily Bus Connections	6 Ø
Distance	216.3 km
Coach Companies	FlixBus

Cheapest coach connections from Pisa to Milan

Every day, 6 buses from 1 coach companies leave Pisa for Milan: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 05/12/2025 and for the following days.

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday

Monday 01/12

Tuesday 02/12

Wednesday 03/12

Thursday 04/12

Friday 05/12

£21

Saturday 06/12

£23

Sunday 07/12

£25

Monday 08/12

£27

Tuesday 09/12

Wednesday 10/12

£24

Thursday 11/12

£17

Friday 12/12

£17

Saturday 13/12

£17

Sunday 14/12

£18

Monday 15/12

£17

Tuesday 16/12

Wednesday 17/12

£16

Thursday 18/12

£16

Friday 19/12

£18

Saturday 20/12

£21

Sunday 21/12

£24

Monday 22/12

£25

Tuesday 23/12

£22

Wednesday 24/12

£21

Thursday 25/12

£21

Friday 26/12

£19

Saturday 27/12

£24

Sunday 28/12

The cheapest time to travel from Pisa to Milan

See here on which day and which time of the day you can find the cheapest bus ticket from Pisa to Milan, for the next 30 days.

With a price starting from £16, Wednesday is the cheapest day for a coach from Pisa to Milan. Sunday instead is the most expensive day with prices starting from £18.

Night is the cheapest day time for bus tickets from Pisa to Milan, with £16. Afternoon is the most expensive time of the day with prices starting from £17.

How to save money travelling from Pisa to Milan

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Pisa to Milan in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Pisa to Milan, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Pisa to Milan are also emptier.

Beloved bus companies from Pisa to Milan

These are the most booked bus companies between Pisa to Milan from our users.

FlixBus from Pisa to Milan

Here you will find the key facts about the FlixBus bus route Pisa to Milan:

Cheapest Price	£17
Fastest Coach	5h 0m
Earliest Coach	04:50
Last Coach	22:00
Daily Connections	6 Ø
Found on	04/12/2025

All bus stations and stops in Pisa and Milan

The map below shows you where to find all the bus stations in Pisa and Milan.

Pietrasantina Bus Station

Via Pietrasantina

Central Bus Station

V.Brennero Porta A Lucca

Parking Aurelia

Ospedale Cisanello Bus Stop

Lampugnano Bus Station

Via Giulio Natta Lampugnano

Rogoredo Bus Station

Via Cassinis Giovanni Battista 76

San Donato Bus Station

Via Giuseppe Impastato 25

Duomo Bus Stop

Piazza del Duomo

Central Bus Station

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Pisa to Milan? Compare all modes of transports from Pisa to Milan.

Service and Comfort on the bus from Pisa to Milan

Want to know which seat classes are available on the coaches from Pisa to Milan? Or which bus companies serve the route Pisa to Milan? Below you will find answers to your questions.

FAQs about the Pisa to Milan bus

How much does a Pisa - Milan coach trip cost?

This depends on, among other things, the day and travel time. The cheapest ticket for the Pisa - Milan bus trip is available from £16 and takes 5h 15m. Compare offers and save money!

How much could I save by comparing buses from Pisa to Milan?

The connection Pisa to Milan is offered by 1 companies with ticket prices ranging from £16 to £54. Therefore, we suggest booking your ticket as soon as possible to ensure you will get the cheapest ticket price.

How many connections are available for the Pisa - Milan route on average every day?

Each day, the bus route from Pisa to Milan is offered by roughly 6 busses. By using our search, you can compare bus schedules and find your ideal trip.

How long does a bus to Milan from Pisa take?

The quickest coach from Pisa to Milan is provided by FlixBus and takes 5h 0m. Coach tickets for this connection cost £21. However, keep in mind that the connection can take longer due to traffic.

What time is the first bus from Pisa to Milan?

The earliest bus to Milan departs from Pisa at 04:50. In this context, information about departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

What time is the last coach from Pisa to Milan?

The latest bus to Milan departs from Pisa at 22:00. Please note that departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

Which bus companies serve the Pisa - Milan route?

Passengers looking to travel from Pisa to Milan can travel with FlixBus. Compare all available bus tickets with our search to book the trip that works best for you.

Is there a direct bus between Pisa and Milan?

You can check all the direct connections between Pisa and Milan by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus.

What can I take with me on the bus to Milan from Pisa?

Depending on which provider you travel with, what you are allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the bus for the Pisa Milan bus route free of charge. Simply use our search to find a coach that is best suited to your needs for your planned travel date.

What equipment is available for the Pisa Milan bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make travelling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Pisa to Milan on your planned travel date.

Available seat classes which are offered on the bus route Pisa to Milan

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Pisa and to Milan

Here’s an overview of the most popular bus routes to Pisa and to Milan. Simply click on the connection of your choice, and you will find all the details about your bus route!