What is the best way to travel from Pisa to Milan?
Looking for a trip? Check and compare all the available Trains and Buses to Milan from Pisa. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 2 available companies to find your perfect trip!
What is the cheapest way to reach Milan from Pisa?
You can reach Milan with just £12 by taking a Bus from FlixBus, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
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FlixBus6h 25m017:10PisaPietrasantina Bus Station23:35MilanLampugnano Bus Station0EconomyA Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 06/05/2026 17:10:00 to Lampugnano Bus Station, Milan (Italy) arriving at 06/05/2026 23:35:00. 50 Economy ticket for £16 per person are available. Travel duration is 6h 25m
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FlixBus6h 55m018:10PisaPietrasantina Bus Station01:05MilanLampugnano Bus Station0EconomyA Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 06/05/2026 18:10:00 to Lampugnano Bus Station, Milan (Italy) arriving at 07/05/2026 01:05:00. 50 Economy ticket for £16 per person are available. Travel duration is 6h 55m
Cheapest Buses Wednesday
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FlixBus5h 15m006:25PisaParking Aurelia11:40MilanSan Donato Bus Station0EconomyA Bus from FlixBus goes from Parking Aurelia, Pisa (Italy) at 07/05/2026 06:25:00 to San Donato Bus Station, Milan (Italy) arriving at 07/05/2026 11:40:00. 50 Economy ticket for £12 per person are available. Travel duration is 5h 15m
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FlixBus5h 40m017:20PisaParking Aurelia23:00MilanSan Donato Bus Station0EconomyA Bus from FlixBus goes from Parking Aurelia, Pisa (Italy) at 07/05/2026 17:20:00 to San Donato Bus Station, Milan (Italy) arriving at 07/05/2026 23:00:00. 50 Economy ticket for £12 per person are available. Travel duration is 5h 40m
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FlixBus6h 0m022:00PisaParking Aurelia04:00MilanLampugnano Bus Station0EconomyA Bus from FlixBus goes from Parking Aurelia, Pisa (Italy) at 07/05/2026 22:00:00 to Lampugnano Bus Station, Milan (Italy) arriving at 08/05/2026 04:00:00. 50 Economy ticket for £12 per person are available. Travel duration is 6h 0m
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FlixBus6h 30m012:00PisaParking Aurelia18:30MilanSan Donato Bus Station0EconomyA Bus from FlixBus goes from Parking Aurelia, Pisa (Italy) at 07/05/2026 12:00:00 to San Donato Bus Station, Milan (Italy) arriving at 07/05/2026 18:30:00. 50 Economy ticket for £13 per person are available. Travel duration is 6h 30m
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FlixBus5h 5m013:50PisaParking Aurelia18:55MilanLampugnano Bus Station0EconomyA Bus from FlixBus goes from Parking Aurelia, Pisa (Italy) at 07/05/2026 13:50:00 to Lampugnano Bus Station, Milan (Italy) arriving at 07/05/2026 18:55:00. 50 Economy ticket for £16 per person are available. Travel duration is 5h 5m
Cheapest Buses Thursday
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FlixBus5h 15m006:25PisaPietrasantina Bus Station11:40MilanSan Donato Bus Station0EconomyA Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 08/05/2026 06:25:00 to San Donato Bus Station, Milan (Italy) arriving at 08/05/2026 11:40:00. 50 Economy ticket for £22 per person are available. Travel duration is 5h 15m
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FlixBus5h 50m017:10PisaPietrasantina Bus Station23:00MilanSan Donato Bus Station0EconomyA Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 08/05/2026 17:10:00 to San Donato Bus Station, Milan (Italy) arriving at 08/05/2026 23:00:00. 50 Economy ticket for £23 per person are available. Travel duration is 5h 50m
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FlixBus6h 35m012:00PisaPietrasantina Bus Station18:35MilanLampugnano Bus Station0EconomyA Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 08/05/2026 12:00:00 to Lampugnano Bus Station, Milan (Italy) arriving at 08/05/2026 18:35:00. 50 Economy ticket for £26 per person are available. Travel duration is 6h 35m
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FlixBus6h 30m012:00PisaPietrasantina Bus Station18:30MilanSan Donato Bus Station0EconomyA Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 08/05/2026 12:00:00 to San Donato Bus Station, Milan (Italy) arriving at 08/05/2026 18:30:00. 50 Economy ticket for £27 per person are available. Travel duration is 6h 30m
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FlixBus6h 45m009:40PisaPietrasantina Bus Station16:25MilanLampugnano Bus Station0EconomyA Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 08/05/2026 09:40:00 to Lampugnano Bus Station, Milan (Italy) arriving at 08/05/2026 16:25:00. 50 Economy ticket for £28 per person are available. Travel duration is 6h 45m
Cheapest Buses Friday
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Trenitalia5h 51m015:24PisaCentral Station21:15MilanCentral Station - Piazza Luigi di Savoia0EconomyA Train from Trenitalia goes from Central Station, Pisa (Italy) at 09/05/2026 15:24:00 to Central Station - Piazza Luigi di Savoia, Milan (Italy) arriving at 09/05/2026 21:15:00. 50 Economy ticket for £14 per person are available. Travel duration is 5h 51m
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Trenitalia4h 58m018:24PisaCentral Station23:22MilanCentral Station - Piazza Luigi di Savoia0EconomyA Train from Trenitalia goes from Central Station, Pisa (Italy) at 09/05/2026 18:24:00 to Central Station - Piazza Luigi di Savoia, Milan (Italy) arriving at 09/05/2026 23:22:00. 50 Economy ticket for £16 per person are available. Travel duration is 4h 58m
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Trenitalia4h 20m017:35PisaCentral Station21:55MilanCentral Station - Piazza Luigi di Savoia0EconomyA Train from Trenitalia goes from Central Station, Pisa (Italy) at 09/05/2026 17:35:00 to Central Station - Piazza Luigi di Savoia, Milan (Italy) arriving at 09/05/2026 21:55:00. 50 Economy ticket for £17 per person are available. Travel duration is 4h 20m
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Trenitalia3h 44m016:56PisaCentral Station20:40MilanCentral Station - Piazza Luigi di Savoia0EconomyA Train from Trenitalia goes from Central Station, Pisa (Italy) at 09/05/2026 16:56:00 to Central Station - Piazza Luigi di Savoia, Milan (Italy) arriving at 09/05/2026 20:40:00. 50 Economy ticket for £21 per person are available. Travel duration is 3h 44m
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Trenitalia4h 18m005:42PisaCentral Station10:00MilanCentral Station - Piazza Luigi di Savoia0EconomyA Train from Trenitalia goes from Central Station, Pisa (Italy) at 09/05/2026 05:42:00 to Central Station - Piazza Luigi di Savoia, Milan (Italy) arriving at 09/05/2026 10:00:00. 50 Economy ticket for £23 per person are available. Travel duration is 4h 18m
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FlixBus5h 40m017:20PisaParking Aurelia23:00MilanSan Donato Bus Station0EconomyA Bus from FlixBus goes from Parking Aurelia, Pisa (Italy) at 09/05/2026 17:20:00 to San Donato Bus Station, Milan (Italy) arriving at 09/05/2026 23:00:00. 50 Economy ticket for £17 per person are available. Travel duration is 5h 40m
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FlixBus5h 5m013:50PisaParking Aurelia18:55MilanLampugnano Bus Station0EconomyA Bus from FlixBus goes from Parking Aurelia, Pisa (Italy) at 09/05/2026 13:50:00 to Lampugnano Bus Station, Milan (Italy) arriving at 09/05/2026 18:55:00. 50 Economy ticket for £17 per person are available. Travel duration is 5h 5m
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FlixBus5h 0m016:45PisaParking Aurelia21:45MilanLampugnano Bus Station0EconomyA Bus from FlixBus goes from Parking Aurelia, Pisa (Italy) at 09/05/2026 16:45:00 to Lampugnano Bus Station, Milan (Italy) arriving at 09/05/2026 21:45:00. 50 Economy ticket for £17 per person are available. Travel duration is 5h 0m
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FlixBus5h 15m006:25PisaParking Aurelia11:40MilanSan Donato Bus Station0EconomyA Bus from FlixBus goes from Parking Aurelia, Pisa (Italy) at 09/05/2026 06:25:00 to San Donato Bus Station, Milan (Italy) arriving at 09/05/2026 11:40:00. 50 Economy ticket for £18 per person are available. Travel duration is 5h 15m
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FlixBus4h 45m017:10PisaPietrasantina Bus Station21:55MilanSan Donato Bus Station0EconomyA Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 09/05/2026 17:10:00 to San Donato Bus Station, Milan (Italy) arriving at 09/05/2026 21:55:00. 50 Economy ticket for £18 per person are available. Travel duration is 4h 45m
Cheapest Trains Saturday
Cheapest Buses Saturday
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FlixBus5h 15m006:25PisaPietrasantina Bus Station11:40MilanSan Donato Bus Station0EconomyA Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 10/05/2026 06:25:00 to San Donato Bus Station, Milan (Italy) arriving at 10/05/2026 11:40:00. 50 Economy ticket for £24 per person are available. Travel duration is 5h 15m
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FlixBus6h 35m012:00PisaPietrasantina Bus Station18:35MilanLampugnano Bus Station0EconomyA Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 10/05/2026 12:00:00 to Lampugnano Bus Station, Milan (Italy) arriving at 10/05/2026 18:35:00. 50 Economy ticket for £28 per person are available. Travel duration is 6h 35m
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FlixBus5h 0m016:45PisaPietrasantina Bus Station21:45MilanLampugnano Bus Station0EconomyA Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 10/05/2026 16:45:00 to Lampugnano Bus Station, Milan (Italy) arriving at 10/05/2026 21:45:00. 50 Economy ticket for £28 per person are available. Travel duration is 5h 0m
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FlixBus5h 5m013:50PisaPietrasantina Bus Station18:55MilanLampugnano Bus Station0EconomyA Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 10/05/2026 13:50:00 to Lampugnano Bus Station, Milan (Italy) arriving at 10/05/2026 18:55:00. 50 Economy ticket for £32 per person are available. Travel duration is 5h 5m
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FlixBus6h 45m009:40PisaPietrasantina Bus Station16:25MilanLampugnano Bus Station0EconomyA Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 10/05/2026 09:40:00 to Lampugnano Bus Station, Milan (Italy) arriving at 10/05/2026 16:25:00. 50 Economy ticket for £34 per person are available. Travel duration is 6h 45m
Cheapest Buses Sunday
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FlixBus6h 0m022:00PisaPietrasantina Bus Station04:00MilanLampugnano Bus Station0EconomyA Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 11/05/2026 22:00:00 to Lampugnano Bus Station, Milan (Italy) arriving at 12/05/2026 04:00:00. 50 Economy ticket for £14 per person are available. Travel duration is 6h 0m
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FlixBus5h 15m006:25PisaPietrasantina Bus Station11:40MilanSan Donato Bus Station0EconomyA Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 11/05/2026 06:25:00 to San Donato Bus Station, Milan (Italy) arriving at 11/05/2026 11:40:00. 50 Economy ticket for £15 per person are available. Travel duration is 5h 15m
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FlixBus5h 50m017:10PisaPietrasantina Bus Station23:00MilanSan Donato Bus Station0EconomyA Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 11/05/2026 17:10:00 to San Donato Bus Station, Milan (Italy) arriving at 11/05/2026 23:00:00. 50 Economy ticket for £16 per person are available. Travel duration is 5h 50m
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FlixBus5h 0m016:45PisaPietrasantina Bus Station21:45MilanLampugnano Bus Station0EconomyA Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 11/05/2026 16:45:00 to Lampugnano Bus Station, Milan (Italy) arriving at 11/05/2026 21:45:00. 50 Economy ticket for £20 per person are available. Travel duration is 5h 0m
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FlixBus5h 5m013:50PisaPietrasantina Bus Station18:55MilanLampugnano Bus Station0EconomyA Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 11/05/2026 13:50:00 to Lampugnano Bus Station, Milan (Italy) arriving at 11/05/2026 18:55:00. 50 Economy ticket for £21 per person are available. Travel duration is 5h 5m
Cheapest Buses Monday
What are the fastest trips from Pisa to Milan?
You can get to Milan from Pisa in just 3h 44m with a Train from Trenitalia. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
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FlixBus6h 25m017:10PisaPietrasantina Bus Station23:35MilanLampugnano Bus Station0EconomyA Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 06/05/2026 17:10:00 to Lampugnano Bus Station, Milan (Italy) arriving at 06/05/2026 23:35:00. 50 Economy ticket for £16 per person are available. Travel duration is 6h 25m
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FlixBus6h 55m018:10PisaPietrasantina Bus Station01:05MilanLampugnano Bus Station0EconomyA Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 06/05/2026 18:10:00 to Lampugnano Bus Station, Milan (Italy) arriving at 07/05/2026 01:05:00. 50 Economy ticket for £16 per person are available. Travel duration is 6h 55m
Fastest Buses Wednesday
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FlixBus5h 5m013:50PisaParking Aurelia18:55MilanLampugnano Bus Station0EconomyA Bus from FlixBus goes from Parking Aurelia, Pisa (Italy) at 07/05/2026 13:50:00 to Lampugnano Bus Station, Milan (Italy) arriving at 07/05/2026 18:55:00. 50 Economy ticket for £16 per person are available. Travel duration is 5h 5m
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FlixBus5h 15m006:25PisaParking Aurelia11:40MilanSan Donato Bus Station0EconomyA Bus from FlixBus goes from Parking Aurelia, Pisa (Italy) at 07/05/2026 06:25:00 to San Donato Bus Station, Milan (Italy) arriving at 07/05/2026 11:40:00. 50 Economy ticket for £12 per person are available. Travel duration is 5h 15m
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FlixBus5h 40m017:20PisaParking Aurelia23:00MilanSan Donato Bus Station0EconomyA Bus from FlixBus goes from Parking Aurelia, Pisa (Italy) at 07/05/2026 17:20:00 to San Donato Bus Station, Milan (Italy) arriving at 07/05/2026 23:00:00. 50 Economy ticket for £12 per person are available. Travel duration is 5h 40m
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FlixBus6h 0m022:00PisaParking Aurelia04:00MilanLampugnano Bus Station0EconomyA Bus from FlixBus goes from Parking Aurelia, Pisa (Italy) at 07/05/2026 22:00:00 to Lampugnano Bus Station, Milan (Italy) arriving at 08/05/2026 04:00:00. 50 Economy ticket for £12 per person are available. Travel duration is 6h 0m
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FlixBus6h 30m012:00PisaParking Aurelia18:30MilanSan Donato Bus Station0EconomyA Bus from FlixBus goes from Parking Aurelia, Pisa (Italy) at 07/05/2026 12:00:00 to San Donato Bus Station, Milan (Italy) arriving at 07/05/2026 18:30:00. 50 Economy ticket for £13 per person are available. Travel duration is 6h 30m
Fastest Buses Thursday
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FlixBus5h 15m006:25PisaPietrasantina Bus Station11:40MilanSan Donato Bus Station0EconomyA Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 08/05/2026 06:25:00 to San Donato Bus Station, Milan (Italy) arriving at 08/05/2026 11:40:00. 50 Economy ticket for £22 per person are available. Travel duration is 5h 15m
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FlixBus5h 50m017:10PisaPietrasantina Bus Station23:00MilanSan Donato Bus Station0EconomyA Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 08/05/2026 17:10:00 to San Donato Bus Station, Milan (Italy) arriving at 08/05/2026 23:00:00. 50 Economy ticket for £23 per person are available. Travel duration is 5h 50m
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FlixBus6h 30m012:00PisaPietrasantina Bus Station18:30MilanSan Donato Bus Station0EconomyA Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 08/05/2026 12:00:00 to San Donato Bus Station, Milan (Italy) arriving at 08/05/2026 18:30:00. 50 Economy ticket for £27 per person are available. Travel duration is 6h 30m
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FlixBus6h 35m012:00PisaPietrasantina Bus Station18:35MilanLampugnano Bus Station0EconomyA Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 08/05/2026 12:00:00 to Lampugnano Bus Station, Milan (Italy) arriving at 08/05/2026 18:35:00. 50 Economy ticket for £26 per person are available. Travel duration is 6h 35m
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FlixBus6h 45m009:40PisaPietrasantina Bus Station16:25MilanLampugnano Bus Station0EconomyA Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 08/05/2026 09:40:00 to Lampugnano Bus Station, Milan (Italy) arriving at 08/05/2026 16:25:00. 50 Economy ticket for £28 per person are available. Travel duration is 6h 45m
Fastest Buses Friday
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Trenitalia3h 44m016:56PisaCentral Station20:40MilanCentral Station - Piazza Luigi di Savoia0EconomyA Train from Trenitalia goes from Central Station, Pisa (Italy) at 09/05/2026 16:56:00 to Central Station - Piazza Luigi di Savoia, Milan (Italy) arriving at 09/05/2026 20:40:00. 50 Economy ticket for £21 per person are available. Travel duration is 3h 44m
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Trenitalia4h 18m005:42PisaCentral Station10:00MilanCentral Station - Piazza Luigi di Savoia0EconomyA Train from Trenitalia goes from Central Station, Pisa (Italy) at 09/05/2026 05:42:00 to Central Station - Piazza Luigi di Savoia, Milan (Italy) arriving at 09/05/2026 10:00:00. 50 Economy ticket for £23 per person are available. Travel duration is 4h 18m
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Trenitalia4h 20m017:35PisaCentral Station21:55MilanCentral Station - Piazza Luigi di Savoia0EconomyA Train from Trenitalia goes from Central Station, Pisa (Italy) at 09/05/2026 17:35:00 to Central Station - Piazza Luigi di Savoia, Milan (Italy) arriving at 09/05/2026 21:55:00. 50 Economy ticket for £17 per person are available. Travel duration is 4h 20m
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Trenitalia4h 58m018:24PisaCentral Station23:22MilanCentral Station - Piazza Luigi di Savoia0EconomyA Train from Trenitalia goes from Central Station, Pisa (Italy) at 09/05/2026 18:24:00 to Central Station - Piazza Luigi di Savoia, Milan (Italy) arriving at 09/05/2026 23:22:00. 50 Economy ticket for £16 per person are available. Travel duration is 4h 58m
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Trenitalia5h 51m015:24PisaCentral Station21:15MilanCentral Station - Piazza Luigi di Savoia0EconomyA Train from Trenitalia goes from Central Station, Pisa (Italy) at 09/05/2026 15:24:00 to Central Station - Piazza Luigi di Savoia, Milan (Italy) arriving at 09/05/2026 21:15:00. 50 Economy ticket for £14 per person are available. Travel duration is 5h 51m
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FlixBus4h 45m017:10PisaPietrasantina Bus Station21:55MilanSan Donato Bus Station0EconomyA Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 09/05/2026 17:10:00 to San Donato Bus Station, Milan (Italy) arriving at 09/05/2026 21:55:00. 50 Economy ticket for £18 per person are available. Travel duration is 4h 45m
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FlixBus5h 0m016:45PisaParking Aurelia21:45MilanLampugnano Bus Station0EconomyA Bus from FlixBus goes from Parking Aurelia, Pisa (Italy) at 09/05/2026 16:45:00 to Lampugnano Bus Station, Milan (Italy) arriving at 09/05/2026 21:45:00. 50 Economy ticket for £17 per person are available. Travel duration is 5h 0m
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FlixBus5h 5m013:50PisaParking Aurelia18:55MilanLampugnano Bus Station0EconomyA Bus from FlixBus goes from Parking Aurelia, Pisa (Italy) at 09/05/2026 13:50:00 to Lampugnano Bus Station, Milan (Italy) arriving at 09/05/2026 18:55:00. 50 Economy ticket for £17 per person are available. Travel duration is 5h 5m
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FlixBus5h 15m006:25PisaParking Aurelia11:40MilanSan Donato Bus Station0EconomyA Bus from FlixBus goes from Parking Aurelia, Pisa (Italy) at 09/05/2026 06:25:00 to San Donato Bus Station, Milan (Italy) arriving at 09/05/2026 11:40:00. 50 Economy ticket for £18 per person are available. Travel duration is 5h 15m
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FlixBus5h 40m017:20PisaParking Aurelia23:00MilanSan Donato Bus Station0EconomyA Bus from FlixBus goes from Parking Aurelia, Pisa (Italy) at 09/05/2026 17:20:00 to San Donato Bus Station, Milan (Italy) arriving at 09/05/2026 23:00:00. 50 Economy ticket for £17 per person are available. Travel duration is 5h 40m
Fastest Trains Saturday
Fastest Buses Saturday
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FlixBus5h 0m016:45PisaPietrasantina Bus Station21:45MilanLampugnano Bus Station0EconomyA Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 10/05/2026 16:45:00 to Lampugnano Bus Station, Milan (Italy) arriving at 10/05/2026 21:45:00. 50 Economy ticket for £28 per person are available. Travel duration is 5h 0m
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FlixBus5h 5m013:50PisaPietrasantina Bus Station18:55MilanLampugnano Bus Station0EconomyA Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 10/05/2026 13:50:00 to Lampugnano Bus Station, Milan (Italy) arriving at 10/05/2026 18:55:00. 50 Economy ticket for £32 per person are available. Travel duration is 5h 5m
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FlixBus5h 15m006:25PisaPietrasantina Bus Station11:40MilanSan Donato Bus Station0EconomyA Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 10/05/2026 06:25:00 to San Donato Bus Station, Milan (Italy) arriving at 10/05/2026 11:40:00. 50 Economy ticket for £24 per person are available. Travel duration is 5h 15m
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FlixBus6h 35m012:00PisaPietrasantina Bus Station18:35MilanLampugnano Bus Station0EconomyA Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 10/05/2026 12:00:00 to Lampugnano Bus Station, Milan (Italy) arriving at 10/05/2026 18:35:00. 50 Economy ticket for £28 per person are available. Travel duration is 6h 35m
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FlixBus6h 45m009:40PisaPietrasantina Bus Station16:25MilanLampugnano Bus Station0EconomyA Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 10/05/2026 09:40:00 to Lampugnano Bus Station, Milan (Italy) arriving at 10/05/2026 16:25:00. 50 Economy ticket for £34 per person are available. Travel duration is 6h 45m
Fastest Buses Sunday
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FlixBus5h 0m016:45PisaPietrasantina Bus Station21:45MilanLampugnano Bus Station0EconomyA Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 11/05/2026 16:45:00 to Lampugnano Bus Station, Milan (Italy) arriving at 11/05/2026 21:45:00. 50 Economy ticket for £20 per person are available. Travel duration is 5h 0m
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FlixBus5h 5m013:50PisaPietrasantina Bus Station18:55MilanLampugnano Bus Station0EconomyA Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 11/05/2026 13:50:00 to Lampugnano Bus Station, Milan (Italy) arriving at 11/05/2026 18:55:00. 50 Economy ticket for £21 per person are available. Travel duration is 5h 5m
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FlixBus5h 15m006:25PisaPietrasantina Bus Station11:40MilanSan Donato Bus Station0EconomyA Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 11/05/2026 06:25:00 to San Donato Bus Station, Milan (Italy) arriving at 11/05/2026 11:40:00. 50 Economy ticket for £15 per person are available. Travel duration is 5h 15m
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FlixBus5h 50m017:10PisaPietrasantina Bus Station23:00MilanSan Donato Bus Station0EconomyA Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 11/05/2026 17:10:00 to San Donato Bus Station, Milan (Italy) arriving at 11/05/2026 23:00:00. 50 Economy ticket for £16 per person are available. Travel duration is 5h 50m
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FlixBus6h 0m022:00PisaPietrasantina Bus Station04:00MilanLampugnano Bus Station0EconomyA Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 11/05/2026 22:00:00 to Lampugnano Bus Station, Milan (Italy) arriving at 12/05/2026 04:00:00. 50 Economy ticket for £14 per person are available. Travel duration is 6h 0m
Fastest Buses Monday
Here you will find all operators and timetables for a
Bus from Pisa to Milan
What are the most popular stations in Pisa and Milan?
In Pisa, you will usually depart from Central Bus Station, Pietrasantina Bus Station or Central Station, while in Milan you will be arriving at Central Station - Piazza Luigi di Savoia, Lampugnano Bus Station or Cadorna Train Station, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Milan from Pisa? With 5 connections between 2 Train and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Pisa and Milan, you can pay as low as £12 with a Bus from FlixBus.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Train from Trenitalia: you will get to Milan in just 3h 44m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Pisa and Milan are FlixBus and Trenitalia, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Pisa and Milan is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Pisa Airport or to Corsico, and look at flights from Pisa Airport, and landing at Bergamo Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Pisa to Milan?
The most popular companies between Pisa and Milan, are FlixBus and Trenitalia. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: FlixBus
Train companies: Trenitalia
All you need to know when you travel from Pisa to Milan
Check all information on comfort and services on all modes of transports from Pisa to Milan. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Pisa to Milan
How can I reach Milan from Pisa?
Every day, there are on average 5 connections between Train and Bus, with which you can get to Milan from Pisa.
How far is Milan from Pisa?
The distance between Pisa and Milan is 216.3 km.
What is the most ecofriendly mode of transport between Pisa and Milan?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 6 kgs of CO2, a train 8 kgs, a car 37 kgs, and a flight 53 kgs.
What is the cheapest mode of transport from Pisa to Milan?
You can get to Milan with just £12 by taking a Bus from FlixBus.
What is the fastest way to get from Pisa to Milan?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Milan in just 3h 44m with a Train from Trenitalia.
More routes to Pisa and to Milan
Looking for more options? Here you can see the most popular routes to Pisa and to Milan. Simply click on a connection, and you’ll find all the details about the route!
