Coach Milan to Siena from £13

Which bus from Milan to Siena is the best?

Check the bus schedule for Milan to Siena. Here is a selection of the cheapest coach trips for the next days from bus operators like FlixBus or Itabus. To see the full timetable for all coaches just use or search and compare.

today

tomorrow

£14

Friday

£14

Saturday

£26

Sunday

Monday

£16

Tuesday

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	5h 45m	15:30	Milan	Lampugnano Bus Station	21:15	Siena	Train Station	Economy	£14	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 18/12/2025 15:30:00 to Train Station, Siena (Italy) arriving at 18/12/2025 21:15:00. 50 Economy ticket for £14 per person are available. Travel duration is 5h 45m
FlixBus	7h 40m	12:00	Milan	Lampugnano Bus Station	19:40	Siena	Train Station	Economy	£15	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 18/12/2025 12:00:00 to Train Station, Siena (Italy) arriving at 18/12/2025 19:40:00. 50 Economy ticket for £15 per person are available. Travel duration is 7h 40m
FlixBus	6h 35m	08:20	Milan	Lampugnano Bus Station	14:55	Siena	Train Station	Economy	£16	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 18/12/2025 08:20:00 to Train Station, Siena (Italy) arriving at 18/12/2025 14:55:00. 50 Economy ticket for £16 per person are available. Travel duration is 6h 35m
FlixBus	4h 55m	00:35	Milan	Lampugnano Bus Station	05:30	Siena	Train Station	Economy	£18	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 18/12/2025 00:35:00 to Train Station, Siena (Italy) arriving at 18/12/2025 05:30:00. 50 Economy ticket for £18 per person are available. Travel duration is 4h 55m
FlixBus	4h 20m	01:10	Milan	San Donato Bus Station	05:30	Siena	Train Station	Economy	£18	A Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 18/12/2025 01:10:00 to Train Station, Siena (Italy) arriving at 18/12/2025 05:30:00. 50 Economy ticket for £18 per person are available. Travel duration is 4h 20m

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	6h 15m	06:15	Milan	Lampugnano Bus Station	12:30	Siena	Train Station	Economy	£14	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 19/12/2025 06:15:00 to Train Station, Siena (Italy) arriving at 19/12/2025 12:30:00. 50 Economy ticket for £14 per person are available. Travel duration is 6h 15m
FlixBus	5h 40m	06:50	Milan	San Donato Bus Station	12:30	Siena	Train Station	Economy	£14	A Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 19/12/2025 06:50:00 to Train Station, Siena (Italy) arriving at 19/12/2025 12:30:00. 50 Economy ticket for £14 per person are available. Travel duration is 5h 40m
FlixBus	7h 25m	08:15	Milan	Lampugnano Bus Station	15:40	Siena	Train Station	Economy	£17	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 19/12/2025 08:15:00 to Train Station, Siena (Italy) arriving at 19/12/2025 15:40:00. 50 Economy ticket for £17 per person are available. Travel duration is 7h 25m
FlixBus	7h 40m	12:00	Milan	Lampugnano Bus Station	19:40	Siena	Train Station	Economy	£17	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 19/12/2025 12:00:00 to Train Station, Siena (Italy) arriving at 19/12/2025 19:40:00. 50 Economy ticket for £17 per person are available. Travel duration is 7h 40m
FlixBus	4h 55m	00:35	Milan	Lampugnano Bus Station	05:30	Siena	Train Station	Economy	£19	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 19/12/2025 00:35:00 to Train Station, Siena (Italy) arriving at 19/12/2025 05:30:00. 50 Economy ticket for £19 per person are available. Travel duration is 4h 55m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Itabus	5h 40m	23:30	Milan	San Donato Bus Station	05:10	Siena	Train Station	Premium Economy	£26	A Bus from Itabus goes from San Donato Bus Station, Milan (Italy) at 20/12/2025 23:30:00 to Train Station, Siena (Italy) arriving at 21/12/2025 05:10:00. 50 Premium Economy ticket for £26 per person are available. Travel duration is 5h 40m
Itabus	6h 30m	22:40	Milan	Lampugnano Bus Station	05:10	Siena	Train Station	Premium Economy	£26	A Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 20/12/2025 22:40:00 to Train Station, Siena (Italy) arriving at 21/12/2025 05:10:00. 50 Premium Economy ticket for £26 per person are available. Travel duration is 6h 30m
Itabus	5h 20m	13:25	Milan	San Donato Bus Station	18:45	Siena	Train Station	Premium Economy	£32	A Bus from Itabus goes from San Donato Bus Station, Milan (Italy) at 20/12/2025 13:25:00 to Train Station, Siena (Italy) arriving at 20/12/2025 18:45:00. 50 Premium Economy ticket for £32 per person are available. Travel duration is 5h 20m
Itabus	5h 15m	00:45	Milan	San Donato Bus Station	06:00	Siena	Train Station	Premium Economy	£50	A Bus from Itabus goes from San Donato Bus Station, Milan (Italy) at 20/12/2025 00:45:00 to Train Station, Siena (Italy) arriving at 20/12/2025 06:00:00. 50 Premium Economy ticket for £50 per person are available. Travel duration is 5h 15m
Itabus	5h 15m	06:50	Milan	San Donato Bus Station	12:05	Siena	Train Station	Premium Economy	£50	A Bus from Itabus goes from San Donato Bus Station, Milan (Italy) at 20/12/2025 06:50:00 to Train Station, Siena (Italy) arriving at 20/12/2025 12:05:00. 50 Premium Economy ticket for £50 per person are available. Travel duration is 5h 15m

Did you know that if you travel from Milan to Siena via Florence, you can save more than £8? You can find the corresponding connections below.
- Distribusion
  
  7h 35m
  
  0
  
  06:50
  
  Milan
  San Donato Bus Station
  
  11:05
  
  Florence
  Villa Costanza Bus Station
  
  0
  
  Premium Economy
  
  £8
  
  A Bus from Distribusion goes from San Donato Bus Station, Milan (Italy) at 21/12/2025 06:50:00 to Villa Costanza Bus Station, Florence (Italy) arriving at 21/12/2025 11:05:00. 50 Premium Economy ticket for £8 per person are available. Travel duration is 4h 15m
- FlixBus
  
  0h 50m
  
  0
  
  13:35
  
  Florence
  Villa Costanza Bus Station
  
  14:25
  
  Siena
  Train Station
  
  0
  
  Economy
  
  £10
  
  A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 21/12/2025 13:35:00 to Train Station, Siena (Italy) arriving at 21/12/2025 14:25:00. 50 Economy ticket for £10 per person are available. Travel duration is 0h 50m
Travel time is 2h 20m longer, but you will save £8

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	7h 25m	08:15	Milan	Lampugnano Bus Station	15:40	Siena	Train Station	Economy	£16	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 22/12/2025 08:15:00 to Train Station, Siena (Italy) arriving at 22/12/2025 15:40:00. 50 Economy ticket for £16 per person are available. Travel duration is 7h 25m
FlixBus	6h 0m	16:20	Milan	Lampugnano Bus Station	22:20	Siena	Train Station	Economy	£17	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 22/12/2025 16:20:00 to Train Station, Siena (Italy) arriving at 22/12/2025 22:20:00. 50 Economy ticket for £17 per person are available. Travel duration is 6h 0m
FlixBus	5h 15m	17:05	Milan	San Donato Bus Station	22:20	Siena	Train Station	Economy	£17	A Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 22/12/2025 17:05:00 to Train Station, Siena (Italy) arriving at 22/12/2025 22:20:00. 50 Economy ticket for £17 per person are available. Travel duration is 5h 15m
Itabus	6h 5m	06:00	Milan	Lampugnano Bus Station	12:05	Siena	Train Station	Premium Economy	£20	A Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 22/12/2025 06:00:00 to Train Station, Siena (Italy) arriving at 22/12/2025 12:05:00. 50 Premium Economy ticket for £20 per person are available. Travel duration is 6h 5m
Itabus	5h 15m	06:50	Milan	San Donato Bus Station	12:05	Siena	Train Station	Premium Economy	£20	A Bus from Itabus goes from San Donato Bus Station, Milan (Italy) at 22/12/2025 06:50:00 to Train Station, Siena (Italy) arriving at 22/12/2025 12:05:00. 50 Premium Economy ticket for £20 per person are available. Travel duration is 5h 15m

Best Price Offer: The price for the cheapest coach from Milan to Siena is £13 on 01/01/2026. Flexible travellers save on ticket prices.

What is the best day and time to travel by bus between Milan and Siena?

Here is the frequency of all coach connections from Milan to Siena. See on which day of the week you have more travel options and what time you have more bus trips to choose from.

Monday is the busiest day, with more than 33 daily coaches from Milan to Siena. Thursday has instead the fewest connections, with only 10 daily coaches between Milan and Siena.

The busiest time of the day is the Afternoon, with 26 coaches from Milan to Siena, while Night sees the fewest connections between Milan and Siena, with 8 offers.

All facts for Milan to Siena bus at a glance

Compare all coach operators like FlixBus and Itabus that travel daily 17 times by bus from Milan to Siena in one click. Book your Milan to Siena bus ticket starting from £13!

Cheapest Bus	£13
Fastest Bus	4h 20m
Earliest Coach	00:35
Latest Coach	23:55
Daily Bus Connections	17 Ø
Distance	293.3 km
Coach Companies	FlixBus and Itabus

What are the cheapest coach tickets from Milan to Siena?

Every day, 17 buses from 2 coach companies leave Milan for Siena. Check the table below to find the cheapest prices for coach tickets for this route, starting from 17/12/2025 and for the following days. Make sure get the cheapest bus ticket!

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday

Monday 15/12

Tuesday 16/12

Wednesday 17/12

Thursday 18/12

£14

Friday 19/12

£14

Saturday 20/12

£21

Sunday 21/12

Monday 22/12

£16

Tuesday 23/12

Wednesday 24/12

£17

Thursday 25/12

£25

Friday 26/12

Saturday 27/12

£18

Sunday 28/12

Monday 29/12

Tuesday 30/12

Wednesday 31/12

Thursday 01/01

£13

Friday 02/01

Saturday 03/01

£14

Sunday 04/01

£17

Monday 05/01

£16

Tuesday 06/01

£23

Wednesday 07/01

Thursday 08/01

Friday 09/01

Saturday 10/01

Sunday 11/01

The cheapest time to travel from Milan to Siena

See here on which day and which time of the day you can find the cheapest bus ticket from Milan to Siena, for the next 30 days.

With a price starting from £13, Thursday is the cheapest day for a coach from Milan to Siena. Monday instead is the most expensive day with prices starting from £16.

Night is the cheapest day time for bus tickets from Milan to Siena, with £13. Evening is the most expensive time of the day with prices starting from £23.

How to save money travelling from Milan to Siena

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying higher prices for your trip? Plan your bus trips smartly. Here are a few hacks to save money on your coach journey.

Book the ticket from Milan to Siena in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the coach from Milan to Siena, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Milan to Siena are also emptier.

Check for bus deals and promotions for all bus companies in this route. On CheckMyBus we show special offers directly in the coach trip on our search. Sign-up and check or deals sections and get notifications on our latest travel hacks.

What are the most popular bus companies from Milan to Siena?

These are the most booked bus companies by our users on the Milan to Siena timetable.

Itabus from Milan to Siena

Here you will find the key facts about the Itabus bus route Milan to Siena:

Cheapest Price	£20
Fastest Coach	5h 15m
Earliest Coach	00:45
Last Coach	23:55
Daily Connections	16 Ø
Found on	16/12/2025

In total 2 operators offer buses for this route. Find all bus timetables for them. Each coach company has a dedicated cancellation policy and possibilities for transport luggage on the bus. Check also special conditions to travel with kids or coach cards with rebates.

All bus stations and stops in Milan and Siena

Here is a map with all coach stations in Milan and Siena. Compare which stop is closest to your destination to save time to find the fastest buses and connections.

Lampugnano Bus Station

Via Giulio Natta Lampugnano

Rogoredo Bus Station

Via Cassinis Giovanni Battista 76

San Donato Bus Station

Via Giuseppe Impastato 25

Duomo Bus Stop

Piazza del Duomo

Central Bus Station

Piazza Antonio Gramsci

Central Bus Station

Bus Stop

Viale Pietro Toselli 9

Colonna San Marco

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Milan to Siena? Compare all modes of transports from Milan to Siena.

All you need to know when you travel by bus from Milan to Siena

Check all information on comfort and services on the coaches from Milan to Siena. Which seat classes are available or what are the amenities of operators on your coach trip? Below you´ll find answers to your questions.

FAQs for Milan to Siena bus

How much does a Milan Siena coach trip cost?

This depends on, among other things, the day and travel time. The cheapest ticket for the Milan Siena bus trip is available from £13 and takes 5h 45m. Compare offers and save money!

How much could I save by comparing buses from Milan to Siena?

This connection is offered by 2 companies with ticket prices ranging from £13 to £62. Therefore, we suggest booking your ticket as soon as possible to ensure you’ll get the cheapest bus trip to Siena.

How many connections are available for the Milan Siena route on average every day?

Each day, the bus route from Milan to Siena is offered by roughly 17 busses. By using our search, you can compare bus schedules and find your ideal trip.

How long does a bus to Siena from Milan take?

The quickest coach from Milan to Siena is provided by FlixBus and takes 4h 20m. Coach tickets for this connection cost £18. However, keep in mind that the connection can take longer due to traffic.

What time is the first bus from Milan to Siena?

The earliest bus to Siena departs from Milan at 00:35. In this context, information about departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

What time is the last coach from Milan to Siena?

The latest bus to Siena departs from Milan at 23:55. Please note that departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

Which bus companies serve the Milan Siena route?

Passengers looking to travel from Milan to Siena can travel with FlixBus and Itabus. Compare all available bus tickets with our search to book the trip that works best for you.

Is there a direct bus between Milan and Siena?

You can check all the direct connections between Milan and Siena by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Itabus.

What can I take with me on the bus to Siena from Milan?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the bus for the Milan Siena bus route free of charge. Simply use our search to find a coach that is best suited to your needs for your planned travel date.

What equipment is available for the Milan Siena bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make travelling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Milan to Siena on your planned travel date.

How does CheckMyBus find the best coach deals from Milan to Siena?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 17 daily trips between Milan and Siena. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Milan to Siena?

Prices and availability for 17 trips between Milan and Siena change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Milan to Siena

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

Premium Economy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

More bus routes to Milan and to Siena

Here’s an overview of the most popular bus routes to Milan and to Siena. Simply click on the connection of your choice, and you’ll find all the details about your bus route!