What is the best way to travel from Milan to Siena?
Looking for a trip? Check and compare all the available Buses, Trains and Carpool to Siena from Milan. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 3 available companies to find your perfect trip!
What is the cheapest way to reach Siena from Milan?
You can reach Siena with just £10 by taking a Bus from FlixBus, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
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FlixBus7h 25m008:15MilanLampugnano Bus Station15:40SienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 05/12/2025 08:15:00 to Train Station, Siena (Italy) arriving at 05/12/2025 15:40:00. 50 Economy ticket for £14 per person are available. Travel duration is 7h 25m
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FlixBus7h 40m012:00MilanLampugnano Bus Station19:40SienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 05/12/2025 12:00:00 to Train Station, Siena (Italy) arriving at 05/12/2025 19:40:00. 50 Economy ticket for £14 per person are available. Travel duration is 7h 40m
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FlixBus5h 45m015:30MilanLampugnano Bus Station21:15SienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 05/12/2025 15:30:00 to Train Station, Siena (Italy) arriving at 05/12/2025 21:15:00. 50 Economy ticket for £18 per person are available. Travel duration is 5h 45m
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Itabus6h 10m012:35Bergamo AirportBergamo Airport18:45SienaCentral Bus Station0EconomyA Bus from Itabus goes from Bergamo Airport, Bergamo Airport (Italy) at 05/12/2025 12:35:00 to Central Bus Station, Siena (Italy) arriving at 05/12/2025 18:45:00. 50 Economy ticket for £27 per person are available. Travel duration is 6h 10m
Cheapest Buses Friday
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FlixBus6h 0m016:20MilanLampugnano Bus Station22:20SienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 06/12/2025 16:20:00 to Train Station, Siena (Italy) arriving at 06/12/2025 22:20:00. 50 Economy ticket for £10 per person are available. Travel duration is 6h 0m
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FlixBus5h 15m017:05MilanSan Donato Bus Station22:20SienaTrain Station0EconomyA Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 06/12/2025 17:05:00 to Train Station, Siena (Italy) arriving at 06/12/2025 22:20:00. 50 Economy ticket for £10 per person are available. Travel duration is 5h 15m
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Itabus7h 30m011:15MilanLampugnano Bus Station18:45SienaTrain Station0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 06/12/2025 11:15:00 to Train Station, Siena (Italy) arriving at 06/12/2025 18:45:00. 50 Premium Economy ticket for £11 per person are available. Travel duration is 7h 30m
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Itabus7h 30m011:15MilanLampugnano Bus Station18:45SienaCentral Bus Station0BasicA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 06/12/2025 11:15:00 to Central Bus Station, Siena (Italy) arriving at 06/12/2025 18:45:00. 50 Basic ticket for £12 per person are available. Travel duration is 7h 30m
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Trenitalia6h 30m012:10MilanCentral Station - Piazza Luigi di Savoia18:40SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 06/12/2025 12:10:00 to Train Station, Siena (Italy) arriving at 06/12/2025 18:40:00. 50 Economy ticket for £41 per person are available. Travel duration is 6h 30m
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Trenitalia6h 28m006:10MilanCentral Station - Piazza Luigi di Savoia12:38SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 06/12/2025 06:10:00 to Train Station, Siena (Italy) arriving at 06/12/2025 12:38:00. 50 Economy ticket for £42 per person are available. Travel duration is 6h 28m
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Trenitalia6h 11m008:05MilanCentral Station - Piazza Luigi di Savoia14:16SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 06/12/2025 08:05:00 to Train Station, Siena (Italy) arriving at 06/12/2025 14:16:00. 50 Economy ticket for £42 per person are available. Travel duration is 6h 11m
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Trenitalia6h 11m014:05MilanCentral Station - Piazza Luigi di Savoia20:16SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 06/12/2025 14:05:00 to Train Station, Siena (Italy) arriving at 06/12/2025 20:16:00. 50 Economy ticket for £42 per person are available. Travel duration is 6h 11m
Cheapest Buses Saturday
Cheapest Trains Saturday
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Itabus5h 15m000:45MilanSan Donato Bus Station06:00SienaTrain Station0Premium EconomyA Bus from Itabus goes from San Donato Bus Station, Milan (Italy) at 07/12/2025 00:45:00 to Train Station, Siena (Italy) arriving at 07/12/2025 06:00:00. 50 Premium Economy ticket for £25 per person are available. Travel duration is 5h 15m
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Itabus5h 15m006:50MilanSan Donato Bus Station12:05SienaTrain Station0Premium EconomyA Bus from Itabus goes from San Donato Bus Station, Milan (Italy) at 07/12/2025 06:50:00 to Train Station, Siena (Italy) arriving at 07/12/2025 12:05:00. 50 Premium Economy ticket for £25 per person are available. Travel duration is 5h 15m
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Itabus6h 5m006:00MilanLampugnano Bus Station12:05SienaTrain Station0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 07/12/2025 06:00:00 to Train Station, Siena (Italy) arriving at 07/12/2025 12:05:00. 50 Premium Economy ticket for £25 per person are available. Travel duration is 6h 5m
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Itabus6h 5m023:55MilanLampugnano Bus Station06:00SienaTrain Station0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 07/12/2025 23:55:00 to Train Station, Siena (Italy) arriving at 08/12/2025 06:00:00. 50 Premium Economy ticket for £25 per person are available. Travel duration is 6h 5m
Cheapest Buses Sunday
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Itabus5h 15m006:50MilanSan Donato Bus Station12:05SienaTrain Station0Premium EconomyA Bus from Itabus goes from San Donato Bus Station, Milan (Italy) at 08/12/2025 06:50:00 to Train Station, Siena (Italy) arriving at 08/12/2025 12:05:00. 50 Premium Economy ticket for £16 per person are available. Travel duration is 5h 15m
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Itabus6h 5m006:00MilanLampugnano Bus Station12:05SienaTrain Station0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 08/12/2025 06:00:00 to Train Station, Siena (Italy) arriving at 08/12/2025 12:05:00. 50 Premium Economy ticket for £16 per person are available. Travel duration is 6h 5m
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FlixBus7h 25m008:15MilanLampugnano Bus Station15:40SienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 08/12/2025 08:15:00 to Train Station, Siena (Italy) arriving at 08/12/2025 15:40:00. 50 Economy ticket for £17 per person are available. Travel duration is 7h 25m
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Itabus5h 15m006:50MilanSan Donato Bus Station12:05SienaCentral Bus Station0BasicA Bus from Itabus goes from San Donato Bus Station, Milan (Italy) at 08/12/2025 06:50:00 to Central Bus Station, Siena (Italy) arriving at 08/12/2025 12:05:00. 50 Basic ticket for £17 per person are available. Travel duration is 5h 15m
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Trenitalia8h 48m010:50MilanCentral Station - Piazza Luigi di Savoia19:38SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 08/12/2025 10:50:00 to Train Station, Siena (Italy) arriving at 08/12/2025 19:38:00. 50 Economy ticket for £25 per person are available. Travel duration is 8h 48m
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Trenitalia7h 26m006:50MilanCentral Station - Piazza Luigi di Savoia14:16SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 08/12/2025 06:50:00 to Train Station, Siena (Italy) arriving at 08/12/2025 14:16:00. 50 Economy ticket for £28 per person are available. Travel duration is 7h 26m
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Trenitalia6h 28m006:10MilanCentral Station - Piazza Luigi di Savoia12:38SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 08/12/2025 06:10:00 to Train Station, Siena (Italy) arriving at 08/12/2025 12:38:00. 50 Economy ticket for £33 per person are available. Travel duration is 6h 28m
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Trenitalia6h 11m008:05MilanCentral Station - Piazza Luigi di Savoia14:16SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 08/12/2025 08:05:00 to Train Station, Siena (Italy) arriving at 08/12/2025 14:16:00. 50 Economy ticket for £35 per person are available. Travel duration is 6h 11m
Cheapest Buses Monday
Cheapest Trains Monday
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Itabus8h 25m020:45Bergamo AirportBergamo Airport05:10SienaTrain Station0Premium EconomyA Bus from Itabus goes from Bergamo Airport, Bergamo Airport (Italy) at 10/12/2025 20:45:00 to Train Station, Siena (Italy) arriving at 11/12/2025 05:10:00. 50 Premium Economy ticket for £18 per person are available. Travel duration is 8h 25m
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Itabus5h 15m006:50MilanSan Donato Bus Station12:05SienaTrain Station0Premium EconomyA Bus from Itabus goes from San Donato Bus Station, Milan (Italy) at 10/12/2025 06:50:00 to Train Station, Siena (Italy) arriving at 10/12/2025 12:05:00. 50 Premium Economy ticket for £21 per person are available. Travel duration is 5h 15m
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Itabus5h 40m023:30MilanSan Donato Bus Station05:10SienaTrain Station0Premium EconomyA Bus from Itabus goes from San Donato Bus Station, Milan (Italy) at 10/12/2025 23:30:00 to Train Station, Siena (Italy) arriving at 11/12/2025 05:10:00. 50 Premium Economy ticket for £21 per person are available. Travel duration is 5h 40m
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FlixBus9h 15m012:00Bergamo AirportBergamo Airport21:15SienaTrain Station0EconomyA Bus from FlixBus goes from Bergamo Airport, Bergamo Airport (Italy) at 10/12/2025 12:00:00 to Train Station, Siena (Italy) arriving at 10/12/2025 21:15:00. 50 Economy ticket for £24 per person are available. Travel duration is 9h 15m
Cheapest Buses Wednesday
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FlixBus6h 35m008:20MilanLampugnano Bus Station14:55SienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 11/12/2025 08:20:00 to Train Station, Siena (Italy) arriving at 11/12/2025 14:55:00. 50 Economy ticket for £10 per person are available. Travel duration is 6h 35m
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FlixBus6h 0m016:20MilanLampugnano Bus Station22:20SienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 11/12/2025 16:20:00 to Train Station, Siena (Italy) arriving at 11/12/2025 22:20:00. 50 Economy ticket for £10 per person are available. Travel duration is 6h 0m
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FlixBus5h 35m014:25MilanSan Donato Bus Station20:00SienaTrain Station0EconomyA Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 11/12/2025 14:25:00 to Train Station, Siena (Italy) arriving at 11/12/2025 20:00:00. 50 Economy ticket for £10 per person are available. Travel duration is 5h 35m
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Itabus7h 30m011:15MilanLampugnano Bus Station18:45SienaTrain Station0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 11/12/2025 11:15:00 to Train Station, Siena (Italy) arriving at 11/12/2025 18:45:00. 50 Premium Economy ticket for £11 per person are available. Travel duration is 7h 30m
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Trenitalia8h 48m010:50MilanCentral Station - Piazza Luigi di Savoia19:38SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 11/12/2025 10:50:00 to Train Station, Siena (Italy) arriving at 11/12/2025 19:38:00. 50 Economy ticket for £25 per person are available. Travel duration is 8h 48m
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Trenitalia6h 28m006:10MilanCentral Station - Piazza Luigi di Savoia12:38SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 11/12/2025 06:10:00 to Train Station, Siena (Italy) arriving at 11/12/2025 12:38:00. 50 Economy ticket for £26 per person are available. Travel duration is 6h 28m
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Trenitalia4h 7m005:10MilanCentral Station - Piazza Luigi di Savoia09:17SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 11/12/2025 05:10:00 to Train Station, Siena (Italy) arriving at 11/12/2025 09:17:00. 50 Economy ticket for £28 per person are available. Travel duration is 4h 7m
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Trenitalia4h 28m005:10MilanCentral Station - Piazza Luigi di Savoia09:38SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 11/12/2025 05:10:00 to Train Station, Siena (Italy) arriving at 11/12/2025 09:38:00. 50 Economy ticket for £28 per person are available. Travel duration is 4h 28m
Cheapest Buses Thursday
Cheapest Trains Thursday
What are the fastest trips from Milan to Siena?
You can get to Siena from Milan in just 4h 6m with a Train from Trenitalia. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
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FlixBus5h 45m015:30MilanLampugnano Bus Station21:15SienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 05/12/2025 15:30:00 to Train Station, Siena (Italy) arriving at 05/12/2025 21:15:00. 50 Economy ticket for £18 per person are available. Travel duration is 5h 45m
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Itabus6h 10m012:35Bergamo AirportBergamo Airport18:45SienaCentral Bus Station0EconomyA Bus from Itabus goes from Bergamo Airport, Bergamo Airport (Italy) at 05/12/2025 12:35:00 to Central Bus Station, Siena (Italy) arriving at 05/12/2025 18:45:00. 50 Economy ticket for £27 per person are available. Travel duration is 6h 10m
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FlixBus7h 25m008:15MilanLampugnano Bus Station15:40SienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 05/12/2025 08:15:00 to Train Station, Siena (Italy) arriving at 05/12/2025 15:40:00. 50 Economy ticket for £14 per person are available. Travel duration is 7h 25m
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FlixBus7h 40m012:00MilanLampugnano Bus Station19:40SienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 05/12/2025 12:00:00 to Train Station, Siena (Italy) arriving at 05/12/2025 19:40:00. 50 Economy ticket for £14 per person are available. Travel duration is 7h 40m
Fastest Buses Friday
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FlixBus5h 15m017:05MilanSan Donato Bus Station22:20SienaTrain Station0EconomyA Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 06/12/2025 17:05:00 to Train Station, Siena (Italy) arriving at 06/12/2025 22:20:00. 50 Economy ticket for £10 per person are available. Travel duration is 5h 15m
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FlixBus6h 0m016:20MilanLampugnano Bus Station22:20SienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 06/12/2025 16:20:00 to Train Station, Siena (Italy) arriving at 06/12/2025 22:20:00. 50 Economy ticket for £10 per person are available. Travel duration is 6h 0m
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Itabus7h 30m011:15MilanLampugnano Bus Station18:45SienaTrain Station0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 06/12/2025 11:15:00 to Train Station, Siena (Italy) arriving at 06/12/2025 18:45:00. 50 Premium Economy ticket for £11 per person are available. Travel duration is 7h 30m
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Itabus7h 30m011:15MilanLampugnano Bus Station18:45SienaCentral Bus Station0BasicA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 06/12/2025 11:15:00 to Central Bus Station, Siena (Italy) arriving at 06/12/2025 18:45:00. 50 Basic ticket for £12 per person are available. Travel duration is 7h 30m
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Trenitalia6h 11m008:05MilanCentral Station - Piazza Luigi di Savoia14:16SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 06/12/2025 08:05:00 to Train Station, Siena (Italy) arriving at 06/12/2025 14:16:00. 50 Economy ticket for £42 per person are available. Travel duration is 6h 11m
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Trenitalia6h 11m014:05MilanCentral Station - Piazza Luigi di Savoia20:16SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 06/12/2025 14:05:00 to Train Station, Siena (Italy) arriving at 06/12/2025 20:16:00. 50 Economy ticket for £42 per person are available. Travel duration is 6h 11m
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Trenitalia6h 28m006:10MilanCentral Station - Piazza Luigi di Savoia12:38SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 06/12/2025 06:10:00 to Train Station, Siena (Italy) arriving at 06/12/2025 12:38:00. 50 Economy ticket for £42 per person are available. Travel duration is 6h 28m
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Trenitalia6h 30m012:10MilanCentral Station - Piazza Luigi di Savoia18:40SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 06/12/2025 12:10:00 to Train Station, Siena (Italy) arriving at 06/12/2025 18:40:00. 50 Economy ticket for £41 per person are available. Travel duration is 6h 30m
Fastest Buses Saturday
Fastest Trains Saturday
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Itabus5h 15m000:45MilanSan Donato Bus Station06:00SienaTrain Station0Premium EconomyA Bus from Itabus goes from San Donato Bus Station, Milan (Italy) at 07/12/2025 00:45:00 to Train Station, Siena (Italy) arriving at 07/12/2025 06:00:00. 50 Premium Economy ticket for £25 per person are available. Travel duration is 5h 15m
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Itabus5h 15m006:50MilanSan Donato Bus Station12:05SienaTrain Station0Premium EconomyA Bus from Itabus goes from San Donato Bus Station, Milan (Italy) at 07/12/2025 06:50:00 to Train Station, Siena (Italy) arriving at 07/12/2025 12:05:00. 50 Premium Economy ticket for £25 per person are available. Travel duration is 5h 15m
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Itabus6h 5m006:00MilanLampugnano Bus Station12:05SienaTrain Station0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 07/12/2025 06:00:00 to Train Station, Siena (Italy) arriving at 07/12/2025 12:05:00. 50 Premium Economy ticket for £25 per person are available. Travel duration is 6h 5m
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Itabus6h 5m023:55MilanLampugnano Bus Station06:00SienaTrain Station0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 07/12/2025 23:55:00 to Train Station, Siena (Italy) arriving at 08/12/2025 06:00:00. 50 Premium Economy ticket for £25 per person are available. Travel duration is 6h 5m
Fastest Buses Sunday
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Itabus5h 15m006:50MilanSan Donato Bus Station12:05SienaTrain Station0Premium EconomyA Bus from Itabus goes from San Donato Bus Station, Milan (Italy) at 08/12/2025 06:50:00 to Train Station, Siena (Italy) arriving at 08/12/2025 12:05:00. 50 Premium Economy ticket for £16 per person are available. Travel duration is 5h 15m
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Itabus5h 15m006:50MilanSan Donato Bus Station12:05SienaCentral Bus Station0BasicA Bus from Itabus goes from San Donato Bus Station, Milan (Italy) at 08/12/2025 06:50:00 to Central Bus Station, Siena (Italy) arriving at 08/12/2025 12:05:00. 50 Basic ticket for £17 per person are available. Travel duration is 5h 15m
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Itabus6h 5m006:00MilanLampugnano Bus Station12:05SienaTrain Station0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 08/12/2025 06:00:00 to Train Station, Siena (Italy) arriving at 08/12/2025 12:05:00. 50 Premium Economy ticket for £16 per person are available. Travel duration is 6h 5m
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FlixBus6h 15m006:15MilanLampugnano Bus Station12:30SienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 08/12/2025 06:15:00 to Train Station, Siena (Italy) arriving at 08/12/2025 12:30:00. 50 Economy ticket for £18 per person are available. Travel duration is 6h 15m
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Trenitalia6h 11m008:05MilanCentral Station - Piazza Luigi di Savoia14:16SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 08/12/2025 08:05:00 to Train Station, Siena (Italy) arriving at 08/12/2025 14:16:00. 50 Economy ticket for £35 per person are available. Travel duration is 6h 11m
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Trenitalia6h 28m006:10MilanCentral Station - Piazza Luigi di Savoia12:38SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 08/12/2025 06:10:00 to Train Station, Siena (Italy) arriving at 08/12/2025 12:38:00. 50 Economy ticket for £33 per person are available. Travel duration is 6h 28m
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Trenitalia6h 30m012:10MilanCentral Station - Piazza Luigi di Savoia18:40SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 08/12/2025 12:10:00 to Train Station, Siena (Italy) arriving at 08/12/2025 18:40:00. 50 Economy ticket for £37 per person are available. Travel duration is 6h 30m
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Trenitalia7h 26m006:50MilanCentral Station - Piazza Luigi di Savoia14:16SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 08/12/2025 06:50:00 to Train Station, Siena (Italy) arriving at 08/12/2025 14:16:00. 50 Economy ticket for £28 per person are available. Travel duration is 7h 26m
Fastest Buses Monday
Fastest Trains Monday
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Itabus5h 15m006:50MilanSan Donato Bus Station12:05SienaTrain Station0Premium EconomyA Bus from Itabus goes from San Donato Bus Station, Milan (Italy) at 10/12/2025 06:50:00 to Train Station, Siena (Italy) arriving at 10/12/2025 12:05:00. 50 Premium Economy ticket for £21 per person are available. Travel duration is 5h 15m
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Itabus5h 40m023:30MilanSan Donato Bus Station05:10SienaTrain Station0Premium EconomyA Bus from Itabus goes from San Donato Bus Station, Milan (Italy) at 10/12/2025 23:30:00 to Train Station, Siena (Italy) arriving at 11/12/2025 05:10:00. 50 Premium Economy ticket for £21 per person are available. Travel duration is 5h 40m
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Itabus8h 25m020:45Bergamo AirportBergamo Airport05:10SienaTrain Station0Premium EconomyA Bus from Itabus goes from Bergamo Airport, Bergamo Airport (Italy) at 10/12/2025 20:45:00 to Train Station, Siena (Italy) arriving at 11/12/2025 05:10:00. 50 Premium Economy ticket for £18 per person are available. Travel duration is 8h 25m
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FlixBus9h 15m012:00Bergamo AirportBergamo Airport21:15SienaTrain Station0EconomyA Bus from FlixBus goes from Bergamo Airport, Bergamo Airport (Italy) at 10/12/2025 12:00:00 to Train Station, Siena (Italy) arriving at 10/12/2025 21:15:00. 50 Economy ticket for £24 per person are available. Travel duration is 9h 15m
Fastest Buses Wednesday
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Trenitalia4h 6m006:10MilanCentral Station - Piazza Luigi di Savoia10:16SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 11/12/2025 06:10:00 to Train Station, Siena (Italy) arriving at 11/12/2025 10:16:00. 50 Economy ticket for £28 per person are available. Travel duration is 4h 6m
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Trenitalia4h 7m005:10MilanCentral Station - Piazza Luigi di Savoia09:17SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 11/12/2025 05:10:00 to Train Station, Siena (Italy) arriving at 11/12/2025 09:17:00. 50 Economy ticket for £28 per person are available. Travel duration is 4h 7m
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Trenitalia4h 28m005:10MilanCentral Station - Piazza Luigi di Savoia09:38SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 11/12/2025 05:10:00 to Train Station, Siena (Italy) arriving at 11/12/2025 09:38:00. 50 Economy ticket for £28 per person are available. Travel duration is 4h 28m
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Trenitalia6h 28m006:10MilanCentral Station - Piazza Luigi di Savoia12:38SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 11/12/2025 06:10:00 to Train Station, Siena (Italy) arriving at 11/12/2025 12:38:00. 50 Economy ticket for £26 per person are available. Travel duration is 6h 28m
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FlixBus5h 35m014:25MilanSan Donato Bus Station20:00SienaTrain Station0EconomyA Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 11/12/2025 14:25:00 to Train Station, Siena (Italy) arriving at 11/12/2025 20:00:00. 50 Economy ticket for £10 per person are available. Travel duration is 5h 35m
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FlixBus6h 0m016:20MilanLampugnano Bus Station22:20SienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 11/12/2025 16:20:00 to Train Station, Siena (Italy) arriving at 11/12/2025 22:20:00. 50 Economy ticket for £10 per person are available. Travel duration is 6h 0m
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FlixBus6h 35m008:20MilanLampugnano Bus Station14:55SienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 11/12/2025 08:20:00 to Train Station, Siena (Italy) arriving at 11/12/2025 14:55:00. 50 Economy ticket for £10 per person are available. Travel duration is 6h 35m
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Itabus7h 30m011:15MilanLampugnano Bus Station18:45SienaTrain Station0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 11/12/2025 11:15:00 to Train Station, Siena (Italy) arriving at 11/12/2025 18:45:00. 50 Premium Economy ticket for £11 per person are available. Travel duration is 7h 30m
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Here you will find all operators and timetables for a
Bus from Milan to Siena
What are the most popular stations in Milan and Siena?
In Milan, you will usually depart from Central Station - Piazza Luigi di Savoia, Lampugnano Bus Station or Cadorna Train Station, while in Siena you will be arriving at Central Bus Station, Train Station or Bus Stop, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Siena from Milan? With 7 connections between 3 Bus, Train and Carpool operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Milan and Siena, you can pay as low as £10 with a Bus from FlixBus.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Train from Trenitalia: you will get to Siena in just 4h 6m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Milan and Siena are Itabus, Trenitalia and FlixBus, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Milan and Siena is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Corsico or to Castagno, and look at flights from Bergamo Airport, and landing at . Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Milan to Siena?
The most popular companies between Milan and Siena, are Itabus, Trenitalia and FlixBus. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: Itabus and FlixBus
Train companies: Trenitalia
All you need to know when you travel from Milan to Siena
Check all information on comfort and services on all modes of transports from Milan to Siena. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Milan to Siena
How can I reach Siena from Milan?
Every day, there are on average 7 connections between Bus, Train and Carpool, with which you can get to Siena from Milan.
How far is Siena from Milan?
The distance between Milan and Siena is 293.3 km.
What is the most ecofriendly mode of transport between Milan and Siena?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 8 kgs of CO2, a train 10 kgs, a car 50 kgs, and a flight 72 kgs.
What is the cheapest mode of transport from Milan to Siena?
You can get to Siena with just £10 by taking a Bus from FlixBus.
What is the fastest way to get from Milan to Siena?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Siena in just 4h 6m with a Train from Trenitalia.
More routes to Milan and to Siena
Looking for more options? Here you can see the most popular routes to Milan and to Siena. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Milan
- Aosta to Milan
- Barcelona to Milan
- Bergamo Airport to Milan
- Bergamo to Milan
- Brescia to Milan
- Breuil-Cervinia to Milan
- Catania to Milan
- Chatillon to Milan
- Geneva to Milan
- Genoa to Milan
- Innsbruck to Milan
- Lugano to Milan
- Lyon to Milan
- Milan Malpensa Airport to Milan
- Munich to Milan
- Naples to Milan
- Nice Airport to Milan
- Paris to Milan
- Parma to Milan
- Pescara to Milan
- Rome to Milan
- Turin to Milan
- Verona to Milan
- Zurich to Milan
- Trips to Siena
- Assisi to Siena
- Avellino to Siena
- Bologna to Siena
- Caserta to Siena
- Cassino to Siena
- Florence Airport to Siena
- Florence to Siena
- Frosinone to Siena
- Grottaminarda to Siena
- Lucca to Siena
- Milan Malpensa Airport to Siena
- Mosciano Sant'Angelo to Siena
- Naples to Siena
- Orvieto to Siena
- Parma to Siena
- Perugia to Siena
- Pescara to Siena
- Pisa to Siena
- Prato to Siena
- Rome to Siena
- Turin to Siena
- Verona to Siena

