What is the best way to travel from Milan to Siena?
Looking for a trip? Check and compare all the available Trains and Buses to Siena from Milan. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 3 available companies to find your perfect trip!
What is the cheapest way to reach Siena from Milan?
You can reach Siena with just £6 by taking a Bus from FlixBus, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
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Itabus5h 40m010:40MilanLampugnano Bus Station16:20SienaTrain Station0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 22/06/2026 10:40:00 to Train Station, Siena (Italy) arriving at 22/06/2026 16:20:00. 50 Premium Economy ticket for £8 per person are available. Travel duration is 5h 40m
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Itabus5h 40m010:40MilanLampugnano Bus Station16:20SienaCentral Bus Station0EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 22/06/2026 10:40:00 to Central Bus Station, Siena (Italy) arriving at 22/06/2026 16:20:00. 50 Economy ticket for £12 per person are available. Travel duration is 5h 40m
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Itabus5h 15m012:35MilanSan Donato Bus Station17:50SienaCentral Bus Station0EconomyA Bus from Itabus goes from San Donato Bus Station, Milan (Italy) at 22/06/2026 12:35:00 to Central Bus Station, Siena (Italy) arriving at 22/06/2026 17:50:00. 50 Economy ticket for £14 per person are available. Travel duration is 5h 15m
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FlixBus6h 50m007:50Milan Linate AirportMilan Linate Airport14:40SienaTrain Station0EconomyA Bus from FlixBus goes from Milan Linate Airport, Milan Linate Airport (Italy) at 22/06/2026 07:50:00 to Train Station, Siena (Italy) arriving at 22/06/2026 14:40:00. 50 Economy ticket for £21 per person are available. Travel duration is 6h 50m
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FlixBus7h 46m003:34Milan Malpensa AirportMilan Malpensa Airport - T111:20SienaTrain Station0EconomyA Bus from FlixBus goes from Milan Malpensa Airport - T1, Milan Malpensa Airport (Italy) at 22/06/2026 03:34:00 to Train Station, Siena (Italy) arriving at 22/06/2026 11:20:00. 50 Economy ticket for £32 per person are available. Travel duration is 7h 46m
Cheapest Buses Monday
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FlixBus4h 55m000:35MilanLampugnano Bus Station05:30SienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 23/06/2026 00:35:00 to Train Station, Siena (Italy) arriving at 23/06/2026 05:30:00. 50 Economy ticket for £6 per person are available. Travel duration is 4h 55m
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FlixBus6h 35m008:20MilanLampugnano Bus Station14:55SienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 23/06/2026 08:20:00 to Train Station, Siena (Italy) arriving at 23/06/2026 14:55:00. 50 Economy ticket for £6 per person are available. Travel duration is 6h 35m
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FlixBus5h 50m012:25MilanLampugnano Bus Station18:15SienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 23/06/2026 12:25:00 to Train Station, Siena (Italy) arriving at 23/06/2026 18:15:00. 50 Economy ticket for £6 per person are available. Travel duration is 5h 50m
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Itabus5h 40m010:40MilanLampugnano Bus Station16:20SienaTrain Station0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 23/06/2026 10:40:00 to Train Station, Siena (Italy) arriving at 23/06/2026 16:20:00. 50 Premium Economy ticket for £7 per person are available. Travel duration is 5h 40m
Cheapest Buses Tuesday
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Itabus5h 40m010:40MilanLampugnano Bus Station16:20SienaTrain Station0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 24/06/2026 10:40:00 to Train Station, Siena (Italy) arriving at 24/06/2026 16:20:00. 50 Premium Economy ticket for £11 per person are available. Travel duration is 5h 40m
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Itabus5h 15m012:35MilanSan Donato Bus Station17:50SienaTrain Station0Premium EconomyA Bus from Itabus goes from San Donato Bus Station, Milan (Italy) at 24/06/2026 12:35:00 to Train Station, Siena (Italy) arriving at 24/06/2026 17:50:00. 50 Premium Economy ticket for £18 per person are available. Travel duration is 5h 15m
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Itabus5h 40m010:40MilanLampugnano Bus Station16:20SienaPiazza Antonio Gramsci0EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 24/06/2026 10:40:00 to Piazza Antonio Gramsci, Siena (Italy) arriving at 24/06/2026 16:20:00. 50 Economy ticket for £18 per person are available. Travel duration is 5h 40m
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Itabus6h 35m009:45Milan Malpensa AirportMilan Malpensa Airport - T216:20SienaTrain Station0Premium EconomyA Bus from Itabus goes from Milan Malpensa Airport - T2, Milan Malpensa Airport (Italy) at 24/06/2026 09:45:00 to Train Station, Siena (Italy) arriving at 24/06/2026 16:20:00. 50 Premium Economy ticket for £19 per person are available. Travel duration is 6h 35m
Cheapest Buses Wednesday
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FlixBus7h 40m012:00MilanLampugnano Bus Station19:40SienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 25/06/2026 12:00:00 to Train Station, Siena (Italy) arriving at 25/06/2026 19:40:00. 50 Economy ticket for £6 per person are available. Travel duration is 7h 40m
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FlixBus6h 50m015:30MilanLampugnano Bus Station22:20SienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 25/06/2026 15:30:00 to Train Station, Siena (Italy) arriving at 25/06/2026 22:20:00. 50 Economy ticket for £6 per person are available. Travel duration is 6h 50m
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FlixBus6h 0m016:20MilanLampugnano Bus Station22:20SienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 25/06/2026 16:20:00 to Train Station, Siena (Italy) arriving at 25/06/2026 22:20:00. 50 Economy ticket for £6 per person are available. Travel duration is 6h 0m
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Itabus5h 40m010:40MilanLampugnano Bus Station16:20SienaTrain Station0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 25/06/2026 10:40:00 to Train Station, Siena (Italy) arriving at 25/06/2026 16:20:00. 50 Premium Economy ticket for £12 per person are available. Travel duration is 5h 40m
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Itabus5h 15m012:35MilanSan Donato Bus Station17:50SienaTrain Station0Premium EconomyA Bus from Itabus goes from San Donato Bus Station, Milan (Italy) at 25/06/2026 12:35:00 to Train Station, Siena (Italy) arriving at 25/06/2026 17:50:00. 50 Premium Economy ticket for £14 per person are available. Travel duration is 5h 15m
Cheapest Buses Thursday
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Itabus5h 40m010:40MilanLampugnano Bus Station16:20SienaTrain Station0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 26/06/2026 10:40:00 to Train Station, Siena (Italy) arriving at 26/06/2026 16:20:00. 50 Premium Economy ticket for £11 per person are available. Travel duration is 5h 40m
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Itabus5h 40m010:40MilanLampugnano Bus Station16:20SienaCentral Bus Station0EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 26/06/2026 10:40:00 to Central Bus Station, Siena (Italy) arriving at 26/06/2026 16:20:00. 50 Economy ticket for £12 per person are available. Travel duration is 5h 40m
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Itabus5h 15m012:35MilanSan Donato Bus Station17:50SienaCentral Bus Station0EconomyA Bus from Itabus goes from San Donato Bus Station, Milan (Italy) at 26/06/2026 12:35:00 to Central Bus Station, Siena (Italy) arriving at 26/06/2026 17:50:00. 50 Economy ticket for £14 per person are available. Travel duration is 5h 15m
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FlixBus6h 50m007:50Milan Linate AirportMilan Linate Airport14:40SienaTrain Station0EconomyA Bus from FlixBus goes from Milan Linate Airport, Milan Linate Airport (Italy) at 26/06/2026 07:50:00 to Train Station, Siena (Italy) arriving at 26/06/2026 14:40:00. 50 Economy ticket for £25 per person are available. Travel duration is 6h 50m
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FlixBus9h 20m010:20Milan Linate AirportMilan Linate Airport19:40SienaTrain Station0EconomyA Bus from FlixBus goes from Milan Linate Airport, Milan Linate Airport (Italy) at 26/06/2026 10:20:00 to Train Station, Siena (Italy) arriving at 26/06/2026 19:40:00. 50 Economy ticket for £27 per person are available. Travel duration is 9h 20m
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Trenitalia8h 47m006:50MilanCentral Station - Piazza Luigi di Savoia15:37SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 26/06/2026 06:50:00 to Train Station, Siena (Italy) arriving at 26/06/2026 15:37:00. 50 Economy ticket for £27 per person are available. Travel duration is 8h 47m
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Trenitalia6h 33m006:05MilanCentral Station - Piazza Luigi di Savoia12:38SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 26/06/2026 06:05:00 to Train Station, Siena (Italy) arriving at 26/06/2026 12:38:00. 50 Economy ticket for £29 per person are available. Travel duration is 6h 33m
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Trenitalia5h 50m013:48MilanCentral Station - Piazza Luigi di Savoia19:38SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 26/06/2026 13:48:00 to Train Station, Siena (Italy) arriving at 26/06/2026 19:38:00. 50 Economy ticket for £29 per person are available. Travel duration is 5h 50m
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Trenitalia5h 28m013:48MilanCentral Station - Piazza Luigi di Savoia19:16SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 26/06/2026 13:48:00 to Train Station, Siena (Italy) arriving at 26/06/2026 19:16:00. 50 Economy ticket for £29 per person are available. Travel duration is 5h 28m
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Trenitalia5h 36m017:40MilanCentral Station - Piazza Luigi di Savoia23:16SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 26/06/2026 17:40:00 to Train Station, Siena (Italy) arriving at 26/06/2026 23:16:00. 50 Economy ticket for £29 per person are available. Travel duration is 5h 36m
Cheapest Buses Friday
Cheapest Trains Friday
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FlixBus5h 45m005:35MilanLampugnano Bus Station11:20SienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 27/06/2026 05:35:00 to Train Station, Siena (Italy) arriving at 27/06/2026 11:20:00. 50 Economy ticket for £9 per person are available. Travel duration is 5h 45m
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FlixBus6h 15m006:15MilanLampugnano Bus Station12:30SienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 27/06/2026 06:15:00 to Train Station, Siena (Italy) arriving at 27/06/2026 12:30:00. 50 Economy ticket for £9 per person are available. Travel duration is 6h 15m
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FlixBus7h 25m008:15MilanLampugnano Bus Station15:40SienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 27/06/2026 08:15:00 to Train Station, Siena (Italy) arriving at 27/06/2026 15:40:00. 50 Economy ticket for £9 per person are available. Travel duration is 7h 25m
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Itabus5h 15m012:35MilanSan Donato Bus Station17:50SienaTrain Station0Premium EconomyA Bus from Itabus goes from San Donato Bus Station, Milan (Italy) at 27/06/2026 12:35:00 to Train Station, Siena (Italy) arriving at 27/06/2026 17:50:00. 50 Premium Economy ticket for £11 per person are available. Travel duration is 5h 15m
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Itabus5h 40m010:40MilanLampugnano Bus Station16:20SienaTrain Station0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 27/06/2026 10:40:00 to Train Station, Siena (Italy) arriving at 27/06/2026 16:20:00. 50 Premium Economy ticket for £11 per person are available. Travel duration is 5h 40m
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Trenitalia5h 36m017:40MilanCentral Station - Piazza Luigi di Savoia23:16SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 27/06/2026 17:40:00 to Train Station, Siena (Italy) arriving at 27/06/2026 23:16:00. 50 Economy ticket for £24 per person are available. Travel duration is 5h 36m
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Trenitalia6h 50m006:50MilanCentral Station - Piazza Luigi di Savoia13:40SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 27/06/2026 06:50:00 to Train Station, Siena (Italy) arriving at 27/06/2026 13:40:00. 50 Economy ticket for £27 per person are available. Travel duration is 6h 50m
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Trenitalia6h 20m006:55MilanCentral Station - Piazza Luigi di Savoia13:15SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 27/06/2026 06:55:00 to Train Station, Siena (Italy) arriving at 27/06/2026 13:15:00. 50 Economy ticket for £30 per person are available. Travel duration is 6h 20m
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Trenitalia6h 45m006:55MilanCentral Station - Piazza Luigi di Savoia13:40SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 27/06/2026 06:55:00 to Train Station, Siena (Italy) arriving at 27/06/2026 13:40:00. 50 Economy ticket for £30 per person are available. Travel duration is 6h 45m
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Trenitalia8h 26m008:14MilanPorta Garibaldi Train Station16:40SienaTrain Station0EconomyA Train from Trenitalia goes from Porta Garibaldi Train Station, Milan (Italy) at 27/06/2026 08:14:00 to Train Station, Siena (Italy) arriving at 27/06/2026 16:40:00. 50 Economy ticket for £31 per person are available. Travel duration is 8h 26m
Cheapest Buses Saturday
Cheapest Trains Saturday
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FlixBus7h 25m008:15MilanLampugnano Bus Station15:40SienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 28/06/2026 08:15:00 to Train Station, Siena (Italy) arriving at 28/06/2026 15:40:00. 50 Economy ticket for £6 per person are available. Travel duration is 7h 25m
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FlixBus6h 35m008:20MilanLampugnano Bus Station14:55SienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 28/06/2026 08:20:00 to Train Station, Siena (Italy) arriving at 28/06/2026 14:55:00. 50 Economy ticket for £6 per person are available. Travel duration is 6h 35m
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FlixBus7h 40m012:00MilanLampugnano Bus Station19:40SienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 28/06/2026 12:00:00 to Train Station, Siena (Italy) arriving at 28/06/2026 19:40:00. 50 Economy ticket for £6 per person are available. Travel duration is 7h 40m
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Itabus5h 15m012:35MilanSan Donato Bus Station17:50SienaTrain Station0Premium EconomyA Bus from Itabus goes from San Donato Bus Station, Milan (Italy) at 28/06/2026 12:35:00 to Train Station, Siena (Italy) arriving at 28/06/2026 17:50:00. 50 Premium Economy ticket for £6 per person are available. Travel duration is 5h 15m
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Itabus5h 15m012:35MilanSan Donato Bus Station17:50SienaCentral Bus Station0EconomyA Bus from Itabus goes from San Donato Bus Station, Milan (Italy) at 28/06/2026 12:35:00 to Central Bus Station, Siena (Italy) arriving at 28/06/2026 17:50:00. 50 Economy ticket for £7 per person are available. Travel duration is 5h 15m
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Trenitalia6h 33m006:05MilanCentral Station - Piazza Luigi di Savoia12:38SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 28/06/2026 06:05:00 to Train Station, Siena (Italy) arriving at 28/06/2026 12:38:00. 50 Economy ticket for £25 per person are available. Travel duration is 6h 33m
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Trenitalia7h 26m006:50MilanCentral Station - Piazza Luigi di Savoia14:16SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 28/06/2026 06:50:00 to Train Station, Siena (Italy) arriving at 28/06/2026 14:16:00. 50 Economy ticket for £28 per person are available. Travel duration is 7h 26m
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Trenitalia5h 50m013:48MilanCentral Station - Piazza Luigi di Savoia19:38SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 28/06/2026 13:48:00 to Train Station, Siena (Italy) arriving at 28/06/2026 19:38:00. 50 Economy ticket for £30 per person are available. Travel duration is 5h 50m
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Trenitalia9h 0m008:14MilanPorta Garibaldi Train Station17:14SienaTrain Station0EconomyA Train from Trenitalia goes from Porta Garibaldi Train Station, Milan (Italy) at 28/06/2026 08:14:00 to Train Station, Siena (Italy) arriving at 28/06/2026 17:14:00. 50 Economy ticket for £32 per person are available. Travel duration is 9h 0m
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Trenitalia6h 57m008:40MilanCentral Station - Piazza Luigi di Savoia15:37SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 28/06/2026 08:40:00 to Train Station, Siena (Italy) arriving at 28/06/2026 15:37:00. 50 Economy ticket for £34 per person are available. Travel duration is 6h 57m
Cheapest Buses Sunday
Cheapest Trains Sunday
What are the fastest trips from Milan to Siena?
You can get to Siena from Milan in just 4h 55m with a Bus from FlixBus. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
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Itabus5h 15m012:35MilanSan Donato Bus Station17:50SienaCentral Bus Station0EconomyA Bus from Itabus goes from San Donato Bus Station, Milan (Italy) at 22/06/2026 12:35:00 to Central Bus Station, Siena (Italy) arriving at 22/06/2026 17:50:00. 50 Economy ticket for £14 per person are available. Travel duration is 5h 15m
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Itabus5h 40m010:40MilanLampugnano Bus Station16:20SienaTrain Station0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 22/06/2026 10:40:00 to Train Station, Siena (Italy) arriving at 22/06/2026 16:20:00. 50 Premium Economy ticket for £8 per person are available. Travel duration is 5h 40m
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Itabus5h 40m010:40MilanLampugnano Bus Station16:20SienaCentral Bus Station0EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 22/06/2026 10:40:00 to Central Bus Station, Siena (Italy) arriving at 22/06/2026 16:20:00. 50 Economy ticket for £12 per person are available. Travel duration is 5h 40m
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FlixBus6h 50m007:50Milan Linate AirportMilan Linate Airport14:40SienaTrain Station0EconomyA Bus from FlixBus goes from Milan Linate Airport, Milan Linate Airport (Italy) at 22/06/2026 07:50:00 to Train Station, Siena (Italy) arriving at 22/06/2026 14:40:00. 50 Economy ticket for £21 per person are available. Travel duration is 6h 50m
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FlixBus7h 46m003:34Milan Malpensa AirportMilan Malpensa Airport - T111:20SienaTrain Station0EconomyA Bus from FlixBus goes from Milan Malpensa Airport - T1, Milan Malpensa Airport (Italy) at 22/06/2026 03:34:00 to Train Station, Siena (Italy) arriving at 22/06/2026 11:20:00. 50 Economy ticket for £32 per person are available. Travel duration is 7h 46m
Fastest Buses Monday
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FlixBus4h 55m000:35MilanLampugnano Bus Station05:30SienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 23/06/2026 00:35:00 to Train Station, Siena (Italy) arriving at 23/06/2026 05:30:00. 50 Economy ticket for £6 per person are available. Travel duration is 4h 55m
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Itabus5h 40m010:40MilanLampugnano Bus Station16:20SienaTrain Station0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 23/06/2026 10:40:00 to Train Station, Siena (Italy) arriving at 23/06/2026 16:20:00. 50 Premium Economy ticket for £7 per person are available. Travel duration is 5h 40m
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FlixBus5h 50m012:25MilanLampugnano Bus Station18:15SienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 23/06/2026 12:25:00 to Train Station, Siena (Italy) arriving at 23/06/2026 18:15:00. 50 Economy ticket for £6 per person are available. Travel duration is 5h 50m
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FlixBus6h 35m008:20MilanLampugnano Bus Station14:55SienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 23/06/2026 08:20:00 to Train Station, Siena (Italy) arriving at 23/06/2026 14:55:00. 50 Economy ticket for £6 per person are available. Travel duration is 6h 35m
Fastest Buses Tuesday
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Itabus5h 15m012:35MilanSan Donato Bus Station17:50SienaTrain Station0Premium EconomyA Bus from Itabus goes from San Donato Bus Station, Milan (Italy) at 24/06/2026 12:35:00 to Train Station, Siena (Italy) arriving at 24/06/2026 17:50:00. 50 Premium Economy ticket for £18 per person are available. Travel duration is 5h 15m
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Itabus5h 40m010:40MilanLampugnano Bus Station16:20SienaTrain Station0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 24/06/2026 10:40:00 to Train Station, Siena (Italy) arriving at 24/06/2026 16:20:00. 50 Premium Economy ticket for £11 per person are available. Travel duration is 5h 40m
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Itabus5h 40m010:40MilanLampugnano Bus Station16:20SienaPiazza Antonio Gramsci0EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 24/06/2026 10:40:00 to Piazza Antonio Gramsci, Siena (Italy) arriving at 24/06/2026 16:20:00. 50 Economy ticket for £18 per person are available. Travel duration is 5h 40m
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Itabus6h 35m009:45Milan Malpensa AirportMilan Malpensa Airport - T216:20SienaTrain Station0Premium EconomyA Bus from Itabus goes from Milan Malpensa Airport - T2, Milan Malpensa Airport (Italy) at 24/06/2026 09:45:00 to Train Station, Siena (Italy) arriving at 24/06/2026 16:20:00. 50 Premium Economy ticket for £19 per person are available. Travel duration is 6h 35m
Fastest Buses Wednesday
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Itabus5h 15m012:35MilanSan Donato Bus Station17:50SienaTrain Station0Premium EconomyA Bus from Itabus goes from San Donato Bus Station, Milan (Italy) at 25/06/2026 12:35:00 to Train Station, Siena (Italy) arriving at 25/06/2026 17:50:00. 50 Premium Economy ticket for £14 per person are available. Travel duration is 5h 15m
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Itabus5h 40m010:40MilanLampugnano Bus Station16:20SienaTrain Station0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 25/06/2026 10:40:00 to Train Station, Siena (Italy) arriving at 25/06/2026 16:20:00. 50 Premium Economy ticket for £12 per person are available. Travel duration is 5h 40m
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FlixBus6h 0m016:20MilanLampugnano Bus Station22:20SienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 25/06/2026 16:20:00 to Train Station, Siena (Italy) arriving at 25/06/2026 22:20:00. 50 Economy ticket for £6 per person are available. Travel duration is 6h 0m
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FlixBus6h 50m015:30MilanLampugnano Bus Station22:20SienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 25/06/2026 15:30:00 to Train Station, Siena (Italy) arriving at 25/06/2026 22:20:00. 50 Economy ticket for £6 per person are available. Travel duration is 6h 50m
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FlixBus7h 40m012:00MilanLampugnano Bus Station19:40SienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 25/06/2026 12:00:00 to Train Station, Siena (Italy) arriving at 25/06/2026 19:40:00. 50 Economy ticket for £6 per person are available. Travel duration is 7h 40m
Fastest Buses Thursday
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Itabus5h 15m012:35MilanSan Donato Bus Station17:50SienaCentral Bus Station0EconomyA Bus from Itabus goes from San Donato Bus Station, Milan (Italy) at 26/06/2026 12:35:00 to Central Bus Station, Siena (Italy) arriving at 26/06/2026 17:50:00. 50 Economy ticket for £14 per person are available. Travel duration is 5h 15m
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Itabus5h 40m010:40MilanLampugnano Bus Station16:20SienaTrain Station0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 26/06/2026 10:40:00 to Train Station, Siena (Italy) arriving at 26/06/2026 16:20:00. 50 Premium Economy ticket for £11 per person are available. Travel duration is 5h 40m
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Itabus5h 40m010:40MilanLampugnano Bus Station16:20SienaCentral Bus Station0EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 26/06/2026 10:40:00 to Central Bus Station, Siena (Italy) arriving at 26/06/2026 16:20:00. 50 Economy ticket for £12 per person are available. Travel duration is 5h 40m
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FlixBus6h 50m007:50Milan Linate AirportMilan Linate Airport14:40SienaTrain Station0EconomyA Bus from FlixBus goes from Milan Linate Airport, Milan Linate Airport (Italy) at 26/06/2026 07:50:00 to Train Station, Siena (Italy) arriving at 26/06/2026 14:40:00. 50 Economy ticket for £25 per person are available. Travel duration is 6h 50m
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FlixBus9h 20m010:20Milan Linate AirportMilan Linate Airport19:40SienaTrain Station0EconomyA Bus from FlixBus goes from Milan Linate Airport, Milan Linate Airport (Italy) at 26/06/2026 10:20:00 to Train Station, Siena (Italy) arriving at 26/06/2026 19:40:00. 50 Economy ticket for £27 per person are available. Travel duration is 9h 20m
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Trenitalia5h 28m013:48MilanCentral Station - Piazza Luigi di Savoia19:16SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 26/06/2026 13:48:00 to Train Station, Siena (Italy) arriving at 26/06/2026 19:16:00. 50 Economy ticket for £29 per person are available. Travel duration is 5h 28m
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Trenitalia5h 36m017:40MilanCentral Station - Piazza Luigi di Savoia23:16SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 26/06/2026 17:40:00 to Train Station, Siena (Italy) arriving at 26/06/2026 23:16:00. 50 Economy ticket for £29 per person are available. Travel duration is 5h 36m
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Trenitalia5h 50m013:48MilanCentral Station - Piazza Luigi di Savoia19:38SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 26/06/2026 13:48:00 to Train Station, Siena (Italy) arriving at 26/06/2026 19:38:00. 50 Economy ticket for £29 per person are available. Travel duration is 5h 50m
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Trenitalia6h 33m006:05MilanCentral Station - Piazza Luigi di Savoia12:38SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 26/06/2026 06:05:00 to Train Station, Siena (Italy) arriving at 26/06/2026 12:38:00. 50 Economy ticket for £29 per person are available. Travel duration is 6h 33m
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Trenitalia8h 47m006:50MilanCentral Station - Piazza Luigi di Savoia15:37SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 26/06/2026 06:50:00 to Train Station, Siena (Italy) arriving at 26/06/2026 15:37:00. 50 Economy ticket for £27 per person are available. Travel duration is 8h 47m
Fastest Buses Friday
Fastest Trains Friday
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Itabus5h 15m012:35MilanSan Donato Bus Station17:50SienaTrain Station0Premium EconomyA Bus from Itabus goes from San Donato Bus Station, Milan (Italy) at 27/06/2026 12:35:00 to Train Station, Siena (Italy) arriving at 27/06/2026 17:50:00. 50 Premium Economy ticket for £11 per person are available. Travel duration is 5h 15m
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Itabus5h 40m010:40MilanLampugnano Bus Station16:20SienaTrain Station0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 27/06/2026 10:40:00 to Train Station, Siena (Italy) arriving at 27/06/2026 16:20:00. 50 Premium Economy ticket for £11 per person are available. Travel duration is 5h 40m
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FlixBus5h 45m005:35MilanLampugnano Bus Station11:20SienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 27/06/2026 05:35:00 to Train Station, Siena (Italy) arriving at 27/06/2026 11:20:00. 50 Economy ticket for £9 per person are available. Travel duration is 5h 45m
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FlixBus6h 15m006:15MilanLampugnano Bus Station12:30SienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 27/06/2026 06:15:00 to Train Station, Siena (Italy) arriving at 27/06/2026 12:30:00. 50 Economy ticket for £9 per person are available. Travel duration is 6h 15m
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FlixBus7h 25m008:15MilanLampugnano Bus Station15:40SienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 27/06/2026 08:15:00 to Train Station, Siena (Italy) arriving at 27/06/2026 15:40:00. 50 Economy ticket for £9 per person are available. Travel duration is 7h 25m
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Trenitalia5h 36m017:40MilanCentral Station - Piazza Luigi di Savoia23:16SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 27/06/2026 17:40:00 to Train Station, Siena (Italy) arriving at 27/06/2026 23:16:00. 50 Economy ticket for £24 per person are available. Travel duration is 5h 36m
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Trenitalia6h 20m006:55MilanCentral Station - Piazza Luigi di Savoia13:15SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 27/06/2026 06:55:00 to Train Station, Siena (Italy) arriving at 27/06/2026 13:15:00. 50 Economy ticket for £30 per person are available. Travel duration is 6h 20m
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Trenitalia6h 45m006:55MilanCentral Station - Piazza Luigi di Savoia13:40SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 27/06/2026 06:55:00 to Train Station, Siena (Italy) arriving at 27/06/2026 13:40:00. 50 Economy ticket for £30 per person are available. Travel duration is 6h 45m
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Trenitalia6h 50m006:50MilanCentral Station - Piazza Luigi di Savoia13:40SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 27/06/2026 06:50:00 to Train Station, Siena (Italy) arriving at 27/06/2026 13:40:00. 50 Economy ticket for £27 per person are available. Travel duration is 6h 50m
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Trenitalia8h 26m008:14MilanPorta Garibaldi Train Station16:40SienaTrain Station0EconomyA Train from Trenitalia goes from Porta Garibaldi Train Station, Milan (Italy) at 27/06/2026 08:14:00 to Train Station, Siena (Italy) arriving at 27/06/2026 16:40:00. 50 Economy ticket for £31 per person are available. Travel duration is 8h 26m
Fastest Buses Saturday
Fastest Trains Saturday
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Itabus5h 15m012:35MilanSan Donato Bus Station17:50SienaTrain Station0Premium EconomyA Bus from Itabus goes from San Donato Bus Station, Milan (Italy) at 28/06/2026 12:35:00 to Train Station, Siena (Italy) arriving at 28/06/2026 17:50:00. 50 Premium Economy ticket for £6 per person are available. Travel duration is 5h 15m
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Itabus5h 15m012:35MilanSan Donato Bus Station17:50SienaCentral Bus Station0EconomyA Bus from Itabus goes from San Donato Bus Station, Milan (Italy) at 28/06/2026 12:35:00 to Central Bus Station, Siena (Italy) arriving at 28/06/2026 17:50:00. 50 Economy ticket for £7 per person are available. Travel duration is 5h 15m
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FlixBus6h 35m008:20MilanLampugnano Bus Station14:55SienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 28/06/2026 08:20:00 to Train Station, Siena (Italy) arriving at 28/06/2026 14:55:00. 50 Economy ticket for £6 per person are available. Travel duration is 6h 35m
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FlixBus7h 25m008:15MilanLampugnano Bus Station15:40SienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 28/06/2026 08:15:00 to Train Station, Siena (Italy) arriving at 28/06/2026 15:40:00. 50 Economy ticket for £6 per person are available. Travel duration is 7h 25m
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FlixBus7h 40m012:00MilanLampugnano Bus Station19:40SienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 28/06/2026 12:00:00 to Train Station, Siena (Italy) arriving at 28/06/2026 19:40:00. 50 Economy ticket for £6 per person are available. Travel duration is 7h 40m
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Trenitalia5h 50m013:48MilanCentral Station - Piazza Luigi di Savoia19:38SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 28/06/2026 13:48:00 to Train Station, Siena (Italy) arriving at 28/06/2026 19:38:00. 50 Economy ticket for £30 per person are available. Travel duration is 5h 50m
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Trenitalia6h 33m006:05MilanCentral Station - Piazza Luigi di Savoia12:38SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 28/06/2026 06:05:00 to Train Station, Siena (Italy) arriving at 28/06/2026 12:38:00. 50 Economy ticket for £25 per person are available. Travel duration is 6h 33m
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Trenitalia6h 57m008:40MilanCentral Station - Piazza Luigi di Savoia15:37SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 28/06/2026 08:40:00 to Train Station, Siena (Italy) arriving at 28/06/2026 15:37:00. 50 Economy ticket for £34 per person are available. Travel duration is 6h 57m
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Trenitalia7h 26m006:50MilanCentral Station - Piazza Luigi di Savoia14:16SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 28/06/2026 06:50:00 to Train Station, Siena (Italy) arriving at 28/06/2026 14:16:00. 50 Economy ticket for £28 per person are available. Travel duration is 7h 26m
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Trenitalia9h 0m008:14MilanPorta Garibaldi Train Station17:14SienaTrain Station0EconomyA Train from Trenitalia goes from Porta Garibaldi Train Station, Milan (Italy) at 28/06/2026 08:14:00 to Train Station, Siena (Italy) arriving at 28/06/2026 17:14:00. 50 Economy ticket for £32 per person are available. Travel duration is 9h 0m
Fastest Buses Sunday
Fastest Trains Sunday
Here you will find all operators and timetables for a
Bus from Milan to Siena
What are the most popular stations in Milan and Siena?
In Milan, you will usually depart from Central Station - Piazza Luigi di Savoia, Lampugnano Bus Station or Cadorna Train Station, while in Siena you will be arriving at Bus Stop, Train Station or Central Bus Station, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Siena from Milan? With 7 connections between 3 Train and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Milan and Siena, you can pay as low as £6 with a Bus from FlixBus.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Bus from FlixBus: you will get to Siena in just 4h 55m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Milan and Siena are Itabus, FlixBus and Trenitalia, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Milan and Siena is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Corsico or to Castagno, and look at flights from Bergamo Airport, and landing at . Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Milan to Siena?
The most popular companies between Milan and Siena, are Itabus, FlixBus and Trenitalia. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: Itabus and FlixBus
Train companies: Trenitalia
All you need to know when you travel from Milan to Siena
Check all information on comfort and services on all modes of transports from Milan to Siena. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Milan to Siena
How can I reach Siena from Milan?
Every day, there are on average 7 connections between Train and Bus, with which you can get to Siena from Milan.
How far is Siena from Milan?
The distance between Milan and Siena is 293.3 km.
What is the most ecofriendly mode of transport between Milan and Siena?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 8 kgs of CO2, a train 10 kgs, a car 50 kgs, and a flight 72 kgs.
What is the cheapest mode of transport from Milan to Siena?
You can get to Siena with just £6 by taking a Bus from FlixBus.
What is the fastest way to get from Milan to Siena?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Siena in just 4h 55m with a Bus from FlixBus.
More routes to Milan and to Siena
Looking for more options? Here you can see the most popular routes to Milan and to Siena. Simply click on a connection, and you’ll find all the details about the route!
