What is the best way to travel from Milan to Siena?
Looking for a trip? Check and compare all the available Trains and Buses to Siena from Milan. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 3 available companies to find your perfect trip!
What is the cheapest way to reach Siena from Milan?
You can reach Siena with just £6 by taking a Bus from Itabus, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
-
Itabus5h 40m010:40MilanLampugnano Bus Station16:20SienaTrain Station0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 04/10/2026 10:40:00 to Train Station, Siena (Italy) arriving at 04/10/2026 16:20:00. 50 Premium Economy ticket for £6 per person are available. Travel duration is 5h 40m
-
Itabus5h 15m012:35MilanSan Donato Bus Station17:50SienaTrain Station0Premium EconomyA Bus from Itabus goes from San Donato Bus Station, Milan (Italy) at 04/10/2026 12:35:00 to Train Station, Siena (Italy) arriving at 04/10/2026 17:50:00. 50 Premium Economy ticket for £13 per person are available. Travel duration is 5h 15m
-
FlixBus7h 35m010:40Bergamo AirportBergamo Airport18:15SienaTrain Station0EconomyA Bus from FlixBus goes from Bergamo Airport, Bergamo Airport (Italy) at 04/10/2026 10:40:00 to Train Station, Siena (Italy) arriving at 04/10/2026 18:15:00. 50 Economy ticket for £20 per person are available. Travel duration is 7h 35m
-
FlixBus9h 20m010:20Milan Linate AirportMilan Linate Airport19:40SienaTrain Station0EconomyA Bus from FlixBus goes from Milan Linate Airport, Milan Linate Airport (Italy) at 04/10/2026 10:20:00 to Train Station, Siena (Italy) arriving at 04/10/2026 19:40:00. 50 Economy ticket for £23 per person are available. Travel duration is 9h 20m
Cheapest Buses Sunday
-
FlixBus6h 35m008:20MilanLampugnano Bus Station14:55SienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 05/10/2026 08:20:00 to Train Station, Siena (Italy) arriving at 05/10/2026 14:55:00. 50 Economy ticket for £11 per person are available. Travel duration is 6h 35m
-
FlixBus6h 0m016:20MilanLampugnano Bus Station22:20SienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 05/10/2026 16:20:00 to Train Station, Siena (Italy) arriving at 05/10/2026 22:20:00. 50 Economy ticket for £11 per person are available. Travel duration is 6h 0m
-
FlixBus5h 15m017:05MilanSan Donato Bus Station22:20SienaTrain Station0EconomyA Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 05/10/2026 17:05:00 to Train Station, Siena (Italy) arriving at 05/10/2026 22:20:00. 50 Economy ticket for £11 per person are available. Travel duration is 5h 15m
-
Itabus5h 40m010:40MilanLampugnano Bus Station16:20SienaTrain Station0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 05/10/2026 10:40:00 to Train Station, Siena (Italy) arriving at 05/10/2026 16:20:00. 50 Premium Economy ticket for £11 per person are available. Travel duration is 5h 40m
-
Itabus5h 40m010:40MilanLampugnano Bus Station16:20SienaCentral Bus Station0EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 05/10/2026 10:40:00 to Central Bus Station, Siena (Italy) arriving at 05/10/2026 16:20:00. 50 Economy ticket for £12 per person are available. Travel duration is 5h 40m
-
Trenitalia7h 20m007:20MilanCentral Station - Piazza Luigi di Savoia14:40SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 05/10/2026 07:20:00 to Train Station, Siena (Italy) arriving at 05/10/2026 14:40:00. 50 Economy ticket for £35 per person are available. Travel duration is 7h 20m
-
Trenitalia6h 33m006:05MilanCentral Station - Piazza Luigi di Savoia12:38SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 05/10/2026 06:05:00 to Train Station, Siena (Italy) arriving at 05/10/2026 12:38:00. 50 Economy ticket for £40 per person are available. Travel duration is 6h 33m
-
Trenitalia8h 35m008:05MilanCentral Station - Piazza Luigi di Savoia16:40SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 05/10/2026 08:05:00 to Train Station, Siena (Italy) arriving at 05/10/2026 16:40:00. 50 Economy ticket for £40 per person are available. Travel duration is 8h 35m
-
Trenitalia6h 30m012:10MilanCentral Station - Piazza Luigi di Savoia18:40SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 05/10/2026 12:10:00 to Train Station, Siena (Italy) arriving at 05/10/2026 18:40:00. 50 Economy ticket for £40 per person are available. Travel duration is 6h 30m
-
Trenitalia5h 36m017:40MilanCentral Station - Piazza Luigi di Savoia23:16SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 05/10/2026 17:40:00 to Train Station, Siena (Italy) arriving at 05/10/2026 23:16:00. 50 Economy ticket for £40 per person are available. Travel duration is 5h 36m
Cheapest Buses Monday
Cheapest Trains Monday
-
Itabus5h 40m010:40MilanLampugnano Bus Station16:20SienaTrain Station0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 06/10/2026 10:40:00 to Train Station, Siena (Italy) arriving at 06/10/2026 16:20:00. 50 Premium Economy ticket for £6 per person are available. Travel duration is 5h 40m
-
Itabus5h 40m023:30MilanSan Donato Bus Station05:10SienaTrain Station0Premium EconomyA Bus from Itabus goes from San Donato Bus Station, Milan (Italy) at 06/10/2026 23:30:00 to Train Station, Siena (Italy) arriving at 07/10/2026 05:10:00. 50 Premium Economy ticket for £13 per person are available. Travel duration is 5h 40m
-
Itabus6h 25m022:45MilanLampugnano Bus Station05:10SienaTrain Station0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 06/10/2026 22:45:00 to Train Station, Siena (Italy) arriving at 07/10/2026 05:10:00. 50 Premium Economy ticket for £13 per person are available. Travel duration is 6h 25m
-
Itabus8h 39m007:41Bergamo AirportBergamo Airport16:20SienaTrain Station0Premium EconomyA Bus from Itabus goes from Bergamo Airport, Bergamo Airport (Italy) at 06/10/2026 07:41:00 to Train Station, Siena (Italy) arriving at 06/10/2026 16:20:00. 50 Premium Economy ticket for £14 per person are available. Travel duration is 8h 39m
-
Trenitalia5h 28m017:48MilanLambrate Train Station23:16SienaTrain Station0EconomyA Train from Trenitalia goes from Lambrate Train Station, Milan (Italy) at 06/10/2026 17:48:00 to Train Station, Siena (Italy) arriving at 06/10/2026 23:16:00. 50 Economy ticket for £20 per person are available. Travel duration is 5h 28m
-
Trenitalia7h 13m007:27MilanLambrate Train Station14:40SienaTrain Station0EconomyA Train from Trenitalia goes from Lambrate Train Station, Milan (Italy) at 06/10/2026 07:27:00 to Train Station, Siena (Italy) arriving at 06/10/2026 14:40:00. 50 Economy ticket for £33 per person are available. Travel duration is 7h 13m
-
Trenitalia8h 28m008:12MilanLambrate Train Station16:40SienaTrain Station0EconomyA Train from Trenitalia goes from Lambrate Train Station, Milan (Italy) at 06/10/2026 08:12:00 to Train Station, Siena (Italy) arriving at 06/10/2026 16:40:00. 50 Economy ticket for £34 per person are available. Travel duration is 8h 28m
-
Trenitalia12h 1m019:27MilanLambrate Train Station07:28SienaTrain Station0EconomyA Train from Trenitalia goes from Lambrate Train Station, Milan (Italy) at 06/10/2026 19:27:00 to Train Station, Siena (Italy) arriving at 07/10/2026 07:28:00. 50 Economy ticket for £37 per person are available. Travel duration is 12h 1m
-
Trenitalia11h 59m019:52MilanLambrate Train Station07:51SienaTrain Station0EconomyA Train from Trenitalia goes from Lambrate Train Station, Milan (Italy) at 06/10/2026 19:52:00 to Train Station, Siena (Italy) arriving at 07/10/2026 07:51:00. 50 Economy ticket for £39 per person are available. Travel duration is 11h 59m
Cheapest Buses Tuesday
Cheapest Trains Tuesday
-
FlixBus4h 55m000:35MilanLampugnano Bus Station05:30SienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 07/10/2026 00:35:00 to Train Station, Siena (Italy) arriving at 07/10/2026 05:30:00. 50 Economy ticket for £6 per person are available. Travel duration is 4h 55m
-
FlixBus6h 35m008:20MilanLampugnano Bus Station14:55SienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 07/10/2026 08:20:00 to Train Station, Siena (Italy) arriving at 07/10/2026 14:55:00. 50 Economy ticket for £6 per person are available. Travel duration is 6h 35m
-
FlixBus5h 50m012:25MilanLampugnano Bus Station18:15SienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 07/10/2026 12:25:00 to Train Station, Siena (Italy) arriving at 07/10/2026 18:15:00. 50 Economy ticket for £6 per person are available. Travel duration is 5h 50m
-
Itabus5h 40m010:40MilanLampugnano Bus Station16:20SienaTrain Station0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 07/10/2026 10:40:00 to Train Station, Siena (Italy) arriving at 07/10/2026 16:20:00. 50 Premium Economy ticket for £6 per person are available. Travel duration is 5h 40m
Cheapest Buses Wednesday
-
FlixBus6h 35m008:20MilanLampugnano Bus Station14:55SienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 08/10/2026 08:20:00 to Train Station, Siena (Italy) arriving at 08/10/2026 14:55:00. 50 Economy ticket for £6 per person are available. Travel duration is 6h 35m
-
FlixBus7h 40m012:00MilanLampugnano Bus Station19:40SienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 08/10/2026 12:00:00 to Train Station, Siena (Italy) arriving at 08/10/2026 19:40:00. 50 Economy ticket for £6 per person are available. Travel duration is 7h 40m
-
FlixBus5h 50m012:25MilanLampugnano Bus Station18:15SienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 08/10/2026 12:25:00 to Train Station, Siena (Italy) arriving at 08/10/2026 18:15:00. 50 Economy ticket for £6 per person are available. Travel duration is 5h 50m
-
Itabus5h 40m010:40MilanLampugnano Bus Station16:20SienaTrain Station0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 08/10/2026 10:40:00 to Train Station, Siena (Italy) arriving at 08/10/2026 16:20:00. 50 Premium Economy ticket for £6 per person are available. Travel duration is 5h 40m
-
Itabus5h 40m010:40MilanLampugnano Bus Station16:20SienaPiazza Antonio Gramsci0EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 08/10/2026 10:40:00 to Piazza Antonio Gramsci, Siena (Italy) arriving at 08/10/2026 16:20:00. 50 Economy ticket for £7 per person are available. Travel duration is 5h 40m
-
Trenitalia5h 28m013:48MilanCentral Station - Piazza Luigi di Savoia19:16SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 08/10/2026 13:48:00 to Train Station, Siena (Italy) arriving at 08/10/2026 19:16:00. 50 Economy ticket for £23 per person are available. Travel duration is 5h 28m
-
Trenitalia5h 50m013:48MilanCentral Station - Piazza Luigi di Savoia19:38SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 08/10/2026 13:48:00 to Train Station, Siena (Italy) arriving at 08/10/2026 19:38:00. 50 Economy ticket for £23 per person are available. Travel duration is 5h 50m
-
Trenitalia5h 36m017:40MilanCentral Station - Piazza Luigi di Savoia23:16SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 08/10/2026 17:40:00 to Train Station, Siena (Italy) arriving at 08/10/2026 23:16:00. 50 Economy ticket for £23 per person are available. Travel duration is 5h 36m
-
Trenitalia6h 33m006:05MilanCentral Station - Piazza Luigi di Savoia12:38SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 08/10/2026 06:05:00 to Train Station, Siena (Italy) arriving at 08/10/2026 12:38:00. 50 Economy ticket for £24 per person are available. Travel duration is 6h 33m
-
Trenitalia6h 28m006:10MilanCentral Station - Piazza Luigi di Savoia12:38SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 08/10/2026 06:10:00 to Train Station, Siena (Italy) arriving at 08/10/2026 12:38:00. 50 Economy ticket for £24 per person are available. Travel duration is 6h 28m
Cheapest Buses Thursday
Cheapest Trains Thursday
-
Itabus5h 40m010:40MilanLampugnano Bus Station16:20SienaTrain Station0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 09/10/2026 10:40:00 to Train Station, Siena (Italy) arriving at 09/10/2026 16:20:00. 50 Premium Economy ticket for £7 per person are available. Travel duration is 5h 40m
-
Itabus5h 40m010:40MilanLampugnano Bus Station16:20SienaPiazza Antonio Gramsci0EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 09/10/2026 10:40:00 to Piazza Antonio Gramsci, Siena (Italy) arriving at 09/10/2026 16:20:00. 50 Economy ticket for £8 per person are available. Travel duration is 5h 40m
-
Itabus5h 40m010:40MilanLampugnano Bus Station16:20SienaCentral Bus Station0EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 09/10/2026 10:40:00 to Central Bus Station, Siena (Italy) arriving at 09/10/2026 16:20:00. 50 Economy ticket for £8 per person are available. Travel duration is 5h 40m
-
FlixBus6h 50m015:30MilanLampugnano Bus Station22:20SienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 09/10/2026 15:30:00 to Train Station, Siena (Italy) arriving at 09/10/2026 22:20:00. 50 Economy ticket for £10 per person are available. Travel duration is 6h 50m
-
FlixBus5h 50m016:30MilanSan Donato Bus Station22:20SienaTrain Station0EconomyA Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 09/10/2026 16:30:00 to Train Station, Siena (Italy) arriving at 09/10/2026 22:20:00. 50 Economy ticket for £10 per person are available. Travel duration is 5h 50m
-
Trenitalia6h 33m006:05MilanCentral Station - Piazza Luigi di Savoia12:38SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 09/10/2026 06:05:00 to Train Station, Siena (Italy) arriving at 09/10/2026 12:38:00. 50 Economy ticket for £32 per person are available. Travel duration is 6h 33m
-
Trenitalia7h 20m007:20MilanCentral Station - Piazza Luigi di Savoia14:40SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 09/10/2026 07:20:00 to Train Station, Siena (Italy) arriving at 09/10/2026 14:40:00. 50 Economy ticket for £35 per person are available. Travel duration is 7h 20m
-
Trenitalia5h 50m013:48MilanCentral Station - Piazza Luigi di Savoia19:38SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 09/10/2026 13:48:00 to Train Station, Siena (Italy) arriving at 09/10/2026 19:38:00. 50 Economy ticket for £40 per person are available. Travel duration is 5h 50m
-
Trenitalia5h 36m017:40MilanCentral Station - Piazza Luigi di Savoia23:16SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 09/10/2026 17:40:00 to Train Station, Siena (Italy) arriving at 09/10/2026 23:16:00. 50 Economy ticket for £40 per person are available. Travel duration is 5h 36m
-
Trenitalia4h 28m005:10MilanCentral Station - Piazza Luigi di Savoia09:38SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 09/10/2026 05:10:00 to Train Station, Siena (Italy) arriving at 09/10/2026 09:38:00. 50 Economy ticket for £41 per person are available. Travel duration is 4h 28m
Cheapest Buses Friday
Cheapest Trains Friday
-
Itabus5h 40m010:40MilanLampugnano Bus Station16:20SienaTrain Station0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 10/10/2026 10:40:00 to Train Station, Siena (Italy) arriving at 10/10/2026 16:20:00. 50 Premium Economy ticket for £6 per person are available. Travel duration is 5h 40m
-
Itabus5h 15m012:35MilanSan Donato Bus Station17:50SienaTrain Station0Premium EconomyA Bus from Itabus goes from San Donato Bus Station, Milan (Italy) at 10/10/2026 12:35:00 to Train Station, Siena (Italy) arriving at 10/10/2026 17:50:00. 50 Premium Economy ticket for £14 per person are available. Travel duration is 5h 15m
-
FlixBus7h 35m010:40Bergamo AirportBergamo Airport18:15SienaTrain Station0EconomyA Bus from FlixBus goes from Bergamo Airport, Bergamo Airport (Italy) at 10/10/2026 10:40:00 to Train Station, Siena (Italy) arriving at 10/10/2026 18:15:00. 50 Economy ticket for £20 per person are available. Travel duration is 7h 35m
-
FlixBus6h 10m013:40Bergamo AirportBergamo Airport19:50SienaTrain Station0EconomyA Bus from FlixBus goes from Bergamo Airport, Bergamo Airport (Italy) at 10/10/2026 13:40:00 to Train Station, Siena (Italy) arriving at 10/10/2026 19:50:00. 50 Economy ticket for £26 per person are available. Travel duration is 6h 10m
Cheapest Buses Saturday
What are the fastest trips from Milan to Siena?
You can get to Siena from Milan in just 4h 28m with a Train from Trenitalia. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
-
Itabus5h 15m012:35MilanSan Donato Bus Station17:50SienaTrain Station0Premium EconomyA Bus from Itabus goes from San Donato Bus Station, Milan (Italy) at 04/10/2026 12:35:00 to Train Station, Siena (Italy) arriving at 04/10/2026 17:50:00. 50 Premium Economy ticket for £13 per person are available. Travel duration is 5h 15m
-
Itabus5h 40m010:40MilanLampugnano Bus Station16:20SienaTrain Station0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 04/10/2026 10:40:00 to Train Station, Siena (Italy) arriving at 04/10/2026 16:20:00. 50 Premium Economy ticket for £6 per person are available. Travel duration is 5h 40m
-
FlixBus7h 35m010:40Bergamo AirportBergamo Airport18:15SienaTrain Station0EconomyA Bus from FlixBus goes from Bergamo Airport, Bergamo Airport (Italy) at 04/10/2026 10:40:00 to Train Station, Siena (Italy) arriving at 04/10/2026 18:15:00. 50 Economy ticket for £20 per person are available. Travel duration is 7h 35m
-
FlixBus9h 20m010:20Milan Linate AirportMilan Linate Airport19:40SienaTrain Station0EconomyA Bus from FlixBus goes from Milan Linate Airport, Milan Linate Airport (Italy) at 04/10/2026 10:20:00 to Train Station, Siena (Italy) arriving at 04/10/2026 19:40:00. 50 Economy ticket for £23 per person are available. Travel duration is 9h 20m
Fastest Buses Sunday
-
FlixBus5h 15m017:05MilanSan Donato Bus Station22:20SienaTrain Station0EconomyA Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 05/10/2026 17:05:00 to Train Station, Siena (Italy) arriving at 05/10/2026 22:20:00. 50 Economy ticket for £11 per person are available. Travel duration is 5h 15m
-
Itabus5h 40m010:40MilanLampugnano Bus Station16:20SienaTrain Station0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 05/10/2026 10:40:00 to Train Station, Siena (Italy) arriving at 05/10/2026 16:20:00. 50 Premium Economy ticket for £11 per person are available. Travel duration is 5h 40m
-
Itabus5h 40m010:40MilanLampugnano Bus Station16:20SienaCentral Bus Station0EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 05/10/2026 10:40:00 to Central Bus Station, Siena (Italy) arriving at 05/10/2026 16:20:00. 50 Economy ticket for £12 per person are available. Travel duration is 5h 40m
-
FlixBus6h 0m016:20MilanLampugnano Bus Station22:20SienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 05/10/2026 16:20:00 to Train Station, Siena (Italy) arriving at 05/10/2026 22:20:00. 50 Economy ticket for £11 per person are available. Travel duration is 6h 0m
-
FlixBus6h 35m008:20MilanLampugnano Bus Station14:55SienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 05/10/2026 08:20:00 to Train Station, Siena (Italy) arriving at 05/10/2026 14:55:00. 50 Economy ticket for £11 per person are available. Travel duration is 6h 35m
-
Trenitalia5h 36m017:40MilanCentral Station - Piazza Luigi di Savoia23:16SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 05/10/2026 17:40:00 to Train Station, Siena (Italy) arriving at 05/10/2026 23:16:00. 50 Economy ticket for £40 per person are available. Travel duration is 5h 36m
-
Trenitalia6h 30m012:10MilanCentral Station - Piazza Luigi di Savoia18:40SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 05/10/2026 12:10:00 to Train Station, Siena (Italy) arriving at 05/10/2026 18:40:00. 50 Economy ticket for £40 per person are available. Travel duration is 6h 30m
-
Trenitalia6h 33m006:05MilanCentral Station - Piazza Luigi di Savoia12:38SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 05/10/2026 06:05:00 to Train Station, Siena (Italy) arriving at 05/10/2026 12:38:00. 50 Economy ticket for £40 per person are available. Travel duration is 6h 33m
-
Trenitalia7h 20m007:20MilanCentral Station - Piazza Luigi di Savoia14:40SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 05/10/2026 07:20:00 to Train Station, Siena (Italy) arriving at 05/10/2026 14:40:00. 50 Economy ticket for £35 per person are available. Travel duration is 7h 20m
-
Trenitalia8h 35m008:05MilanCentral Station - Piazza Luigi di Savoia16:40SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 05/10/2026 08:05:00 to Train Station, Siena (Italy) arriving at 05/10/2026 16:40:00. 50 Economy ticket for £40 per person are available. Travel duration is 8h 35m
Fastest Buses Monday
Fastest Trains Monday
-
Trenitalia5h 28m017:48MilanLambrate Train Station23:16SienaTrain Station0EconomyA Train from Trenitalia goes from Lambrate Train Station, Milan (Italy) at 06/10/2026 17:48:00 to Train Station, Siena (Italy) arriving at 06/10/2026 23:16:00. 50 Economy ticket for £20 per person are available. Travel duration is 5h 28m
-
Trenitalia7h 13m007:27MilanLambrate Train Station14:40SienaTrain Station0EconomyA Train from Trenitalia goes from Lambrate Train Station, Milan (Italy) at 06/10/2026 07:27:00 to Train Station, Siena (Italy) arriving at 06/10/2026 14:40:00. 50 Economy ticket for £33 per person are available. Travel duration is 7h 13m
-
Trenitalia8h 28m008:12MilanLambrate Train Station16:40SienaTrain Station0EconomyA Train from Trenitalia goes from Lambrate Train Station, Milan (Italy) at 06/10/2026 08:12:00 to Train Station, Siena (Italy) arriving at 06/10/2026 16:40:00. 50 Economy ticket for £34 per person are available. Travel duration is 8h 28m
-
Trenitalia11h 59m019:52MilanLambrate Train Station07:51SienaTrain Station0EconomyA Train from Trenitalia goes from Lambrate Train Station, Milan (Italy) at 06/10/2026 19:52:00 to Train Station, Siena (Italy) arriving at 07/10/2026 07:51:00. 50 Economy ticket for £39 per person are available. Travel duration is 11h 59m
-
Trenitalia12h 1m019:27MilanLambrate Train Station07:28SienaTrain Station0EconomyA Train from Trenitalia goes from Lambrate Train Station, Milan (Italy) at 06/10/2026 19:27:00 to Train Station, Siena (Italy) arriving at 07/10/2026 07:28:00. 50 Economy ticket for £37 per person are available. Travel duration is 12h 1m
-
Itabus5h 40m010:40MilanLampugnano Bus Station16:20SienaTrain Station0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 06/10/2026 10:40:00 to Train Station, Siena (Italy) arriving at 06/10/2026 16:20:00. 50 Premium Economy ticket for £6 per person are available. Travel duration is 5h 40m
-
Itabus5h 40m023:30MilanSan Donato Bus Station05:10SienaTrain Station0Premium EconomyA Bus from Itabus goes from San Donato Bus Station, Milan (Italy) at 06/10/2026 23:30:00 to Train Station, Siena (Italy) arriving at 07/10/2026 05:10:00. 50 Premium Economy ticket for £13 per person are available. Travel duration is 5h 40m
-
Itabus6h 25m022:45MilanLampugnano Bus Station05:10SienaTrain Station0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 06/10/2026 22:45:00 to Train Station, Siena (Italy) arriving at 07/10/2026 05:10:00. 50 Premium Economy ticket for £13 per person are available. Travel duration is 6h 25m
-
Itabus8h 39m007:41Bergamo AirportBergamo Airport16:20SienaTrain Station0Premium EconomyA Bus from Itabus goes from Bergamo Airport, Bergamo Airport (Italy) at 06/10/2026 07:41:00 to Train Station, Siena (Italy) arriving at 06/10/2026 16:20:00. 50 Premium Economy ticket for £14 per person are available. Travel duration is 8h 39m
Fastest Trains Tuesday
Fastest Buses Tuesday
-
FlixBus4h 55m000:35MilanLampugnano Bus Station05:30SienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 07/10/2026 00:35:00 to Train Station, Siena (Italy) arriving at 07/10/2026 05:30:00. 50 Economy ticket for £6 per person are available. Travel duration is 4h 55m
-
Itabus5h 40m010:40MilanLampugnano Bus Station16:20SienaTrain Station0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 07/10/2026 10:40:00 to Train Station, Siena (Italy) arriving at 07/10/2026 16:20:00. 50 Premium Economy ticket for £6 per person are available. Travel duration is 5h 40m
-
FlixBus5h 50m012:25MilanLampugnano Bus Station18:15SienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 07/10/2026 12:25:00 to Train Station, Siena (Italy) arriving at 07/10/2026 18:15:00. 50 Economy ticket for £6 per person are available. Travel duration is 5h 50m
-
FlixBus6h 35m008:20MilanLampugnano Bus Station14:55SienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 07/10/2026 08:20:00 to Train Station, Siena (Italy) arriving at 07/10/2026 14:55:00. 50 Economy ticket for £6 per person are available. Travel duration is 6h 35m
Fastest Buses Wednesday
-
Trenitalia5h 28m013:48MilanCentral Station - Piazza Luigi di Savoia19:16SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 08/10/2026 13:48:00 to Train Station, Siena (Italy) arriving at 08/10/2026 19:16:00. 50 Economy ticket for £23 per person are available. Travel duration is 5h 28m
-
Trenitalia5h 36m017:40MilanCentral Station - Piazza Luigi di Savoia23:16SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 08/10/2026 17:40:00 to Train Station, Siena (Italy) arriving at 08/10/2026 23:16:00. 50 Economy ticket for £23 per person are available. Travel duration is 5h 36m
-
Trenitalia5h 50m013:48MilanCentral Station - Piazza Luigi di Savoia19:38SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 08/10/2026 13:48:00 to Train Station, Siena (Italy) arriving at 08/10/2026 19:38:00. 50 Economy ticket for £23 per person are available. Travel duration is 5h 50m
-
Trenitalia6h 28m006:10MilanCentral Station - Piazza Luigi di Savoia12:38SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 08/10/2026 06:10:00 to Train Station, Siena (Italy) arriving at 08/10/2026 12:38:00. 50 Economy ticket for £24 per person are available. Travel duration is 6h 28m
-
Trenitalia6h 33m006:05MilanCentral Station - Piazza Luigi di Savoia12:38SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 08/10/2026 06:05:00 to Train Station, Siena (Italy) arriving at 08/10/2026 12:38:00. 50 Economy ticket for £24 per person are available. Travel duration is 6h 33m
-
Itabus5h 40m010:40MilanLampugnano Bus Station16:20SienaTrain Station0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 08/10/2026 10:40:00 to Train Station, Siena (Italy) arriving at 08/10/2026 16:20:00. 50 Premium Economy ticket for £6 per person are available. Travel duration is 5h 40m
-
Itabus5h 40m010:40MilanLampugnano Bus Station16:20SienaPiazza Antonio Gramsci0EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 08/10/2026 10:40:00 to Piazza Antonio Gramsci, Siena (Italy) arriving at 08/10/2026 16:20:00. 50 Economy ticket for £7 per person are available. Travel duration is 5h 40m
-
FlixBus5h 50m012:25MilanLampugnano Bus Station18:15SienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 08/10/2026 12:25:00 to Train Station, Siena (Italy) arriving at 08/10/2026 18:15:00. 50 Economy ticket for £6 per person are available. Travel duration is 5h 50m
-
FlixBus6h 35m008:20MilanLampugnano Bus Station14:55SienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 08/10/2026 08:20:00 to Train Station, Siena (Italy) arriving at 08/10/2026 14:55:00. 50 Economy ticket for £6 per person are available. Travel duration is 6h 35m
-
FlixBus7h 40m012:00MilanLampugnano Bus Station19:40SienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 08/10/2026 12:00:00 to Train Station, Siena (Italy) arriving at 08/10/2026 19:40:00. 50 Economy ticket for £6 per person are available. Travel duration is 7h 40m
Fastest Trains Thursday
Fastest Buses Thursday
-
Trenitalia4h 28m005:10MilanCentral Station - Piazza Luigi di Savoia09:38SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 09/10/2026 05:10:00 to Train Station, Siena (Italy) arriving at 09/10/2026 09:38:00. 50 Economy ticket for £41 per person are available. Travel duration is 4h 28m
-
Trenitalia5h 36m017:40MilanCentral Station - Piazza Luigi di Savoia23:16SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 09/10/2026 17:40:00 to Train Station, Siena (Italy) arriving at 09/10/2026 23:16:00. 50 Economy ticket for £40 per person are available. Travel duration is 5h 36m
-
Trenitalia5h 50m013:48MilanCentral Station - Piazza Luigi di Savoia19:38SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 09/10/2026 13:48:00 to Train Station, Siena (Italy) arriving at 09/10/2026 19:38:00. 50 Economy ticket for £40 per person are available. Travel duration is 5h 50m
-
Trenitalia6h 33m006:05MilanCentral Station - Piazza Luigi di Savoia12:38SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 09/10/2026 06:05:00 to Train Station, Siena (Italy) arriving at 09/10/2026 12:38:00. 50 Economy ticket for £32 per person are available. Travel duration is 6h 33m
-
Trenitalia7h 20m007:20MilanCentral Station - Piazza Luigi di Savoia14:40SienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 09/10/2026 07:20:00 to Train Station, Siena (Italy) arriving at 09/10/2026 14:40:00. 50 Economy ticket for £35 per person are available. Travel duration is 7h 20m
-
Itabus5h 40m010:40MilanLampugnano Bus Station16:20SienaTrain Station0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 09/10/2026 10:40:00 to Train Station, Siena (Italy) arriving at 09/10/2026 16:20:00. 50 Premium Economy ticket for £7 per person are available. Travel duration is 5h 40m
-
Itabus5h 40m010:40MilanLampugnano Bus Station16:20SienaPiazza Antonio Gramsci0EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 09/10/2026 10:40:00 to Piazza Antonio Gramsci, Siena (Italy) arriving at 09/10/2026 16:20:00. 50 Economy ticket for £8 per person are available. Travel duration is 5h 40m
-
Itabus5h 40m010:40MilanLampugnano Bus Station16:20SienaCentral Bus Station0EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 09/10/2026 10:40:00 to Central Bus Station, Siena (Italy) arriving at 09/10/2026 16:20:00. 50 Economy ticket for £8 per person are available. Travel duration is 5h 40m
-
FlixBus5h 50m016:30MilanSan Donato Bus Station22:20SienaTrain Station0EconomyA Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 09/10/2026 16:30:00 to Train Station, Siena (Italy) arriving at 09/10/2026 22:20:00. 50 Economy ticket for £10 per person are available. Travel duration is 5h 50m
-
FlixBus6h 50m015:30MilanLampugnano Bus Station22:20SienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 09/10/2026 15:30:00 to Train Station, Siena (Italy) arriving at 09/10/2026 22:20:00. 50 Economy ticket for £10 per person are available. Travel duration is 6h 50m
Fastest Trains Friday
Fastest Buses Friday
-
Itabus5h 15m012:35MilanSan Donato Bus Station17:50SienaTrain Station0Premium EconomyA Bus from Itabus goes from San Donato Bus Station, Milan (Italy) at 10/10/2026 12:35:00 to Train Station, Siena (Italy) arriving at 10/10/2026 17:50:00. 50 Premium Economy ticket for £14 per person are available. Travel duration is 5h 15m
-
Itabus5h 40m010:40MilanLampugnano Bus Station16:20SienaTrain Station0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 10/10/2026 10:40:00 to Train Station, Siena (Italy) arriving at 10/10/2026 16:20:00. 50 Premium Economy ticket for £6 per person are available. Travel duration is 5h 40m
-
FlixBus6h 10m013:40Bergamo AirportBergamo Airport19:50SienaTrain Station0EconomyA Bus from FlixBus goes from Bergamo Airport, Bergamo Airport (Italy) at 10/10/2026 13:40:00 to Train Station, Siena (Italy) arriving at 10/10/2026 19:50:00. 50 Economy ticket for £26 per person are available. Travel duration is 6h 10m
-
FlixBus7h 35m010:40Bergamo AirportBergamo Airport18:15SienaTrain Station0EconomyA Bus from FlixBus goes from Bergamo Airport, Bergamo Airport (Italy) at 10/10/2026 10:40:00 to Train Station, Siena (Italy) arriving at 10/10/2026 18:15:00. 50 Economy ticket for £20 per person are available. Travel duration is 7h 35m
Fastest Buses Saturday
Here you will find all operators and timetables for a
Bus from Milan to Siena
What are the most popular stations in Milan and Siena?
In Milan, you will usually depart from Lampugnano Bus Station, Cadorna Train Station or Central Station - Piazza Luigi di Savoia, while in Siena you will be arriving at Central Bus Station, Train Station or Bus Stop, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Siena from Milan? With 7 connections between 3 Train and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Milan and Siena, you can pay as low as £6 with a Bus from Itabus.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Train from Trenitalia: you will get to Siena in just 4h 28m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Milan and Siena are Itabus, Trenitalia and FlixBus, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Milan and Siena is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Corsico or to Castagno, and look at flights from Bergamo Airport, and landing at . Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Milan to Siena?
The most popular companies between Milan and Siena, are Itabus, Trenitalia and FlixBus. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: Itabus and FlixBus
Train companies: Trenitalia
All you need to know when you travel from Milan to Siena
Check all information on comfort and services on all modes of transports from Milan to Siena. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Milan to Siena
How can I reach Siena from Milan?
Every day, there are on average 7 connections between Train and Bus, with which you can get to Siena from Milan.
How far is Siena from Milan?
The distance between Milan and Siena is 293.3 km.
What is the most ecofriendly mode of transport between Milan and Siena?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 8 kgs of CO2, a train 10 kgs, a car 50 kgs, and a flight 72 kgs.
What is the cheapest mode of transport from Milan to Siena?
You can get to Siena with just £6 by taking a Bus from Itabus.
What is the fastest way to get from Milan to Siena?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Siena in just 4h 28m with a Train from Trenitalia.
More routes to Milan and to Siena
Looking for more options? Here you can see the most popular routes to Milan and to Siena. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Milan
- Aosta to Milan
- Basel to Milan
- Bergamo Airport to Milan
- Bologna to Milan
- Courmayeur to Milan
- Foggia to Milan
- Geneva to Milan
- Genoa to Milan
- Lugano to Milan
- Lyon to Milan
- Milan Linate Airport to Milan
- Milan Malpensa Airport to Milan
- Munich to Milan
- Naples to Milan
- Nice to Milan
- Paris to Milan
- Pont-Saint-Martin to Milan
- Reggio Calabria to Milan
- Rimini to Milan
- Rome to Milan
- Trieste to Milan
- Turin to Milan
- Villa San Giovanni to Milan
- Zurich to Milan
- Trips to Siena
- Avellino to Siena
- Bologna to Siena
- Caserta to Siena
- Cassino to Siena
- Chieti to Siena
- Eboli to Siena
- Fiumicino to Siena
- Florence to Siena
- Genoa to Siena
- Lamezia Terme to Siena
- Lucca to Siena
- Naples to Siena
- Perugia to Siena
- Pescara to Siena
- Pisa to Siena
- Rome to Siena
- Salerno to Siena
- Turin to Siena
