Bus and Coach from Milan to Karlsruhe: Compare all prices

Compare all timetables for the bus from Milan to Karlsruhe

Here is a selection of the cheapest bus trips from the schedule from Milan to Karlsruhe from various bus operators like FlixBus or BlaBlaCar Bus for the next days.

today

£30

tomorrow

£29

Saturday

£29

Sunday

£32

Monday

£27

Tuesday

£29

Wednesday

£28

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	7h 50m	20:25	Milan	Lampugnano Bus Station	04:15	Karlsruhe	Central Station	Economy	£30	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 18/06/2026 20:25:00 to Central Station, Karlsruhe (Germany) arriving at 19/06/2026 04:15:00. 50 Economy ticket for £30 per person are available. Travel duration is 7h 50m
FlixBus	8h 20m	21:50	Milan	Lampugnano Bus Station	06:10	Karlsruhe	Central Station	Economy	£31	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 18/06/2026 21:50:00 to Central Station, Karlsruhe (Germany) arriving at 19/06/2026 06:10:00. 50 Economy ticket for £31 per person are available. Travel duration is 8h 20m
FlixBus	9h 5m	23:45	Milan	Lampugnano Bus Station	08:50	Karlsruhe	Central Station	Economy	£31	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 18/06/2026 23:45:00 to Central Station, Karlsruhe (Germany) arriving at 19/06/2026 08:50:00. 50 Economy ticket for £31 per person are available. Travel duration is 9h 5m
FlixBus	8h 20m	07:15	Milan	Lampugnano Bus Station	15:35	Karlsruhe	Central Station	Economy	£33	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 18/06/2026 07:15:00 to Central Station, Karlsruhe (Germany) arriving at 18/06/2026 15:35:00. 50 Economy ticket for £33 per person are available. Travel duration is 8h 20m
FlixBus	9h 55m	01:15	Milan	Lampugnano Bus Station	11:10	Karlsruhe	Central Station	Economy	£34	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 18/06/2026 01:15:00 to Central Station, Karlsruhe (Germany) arriving at 18/06/2026 11:10:00. 50 Economy ticket for £34 per person are available. Travel duration is 9h 55m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
BlaBlaCar Bus	11h 45m	15:20	Milan	Lampugnano Bus Station	03:05	Karlsruhe	Central Station	Economy	£29	A Bus from BlaBlaCar Bus goes from Lampugnano Bus Station, Milan (Italy) at 19/06/2026 15:20:00 to Central Station, Karlsruhe (Germany) arriving at 20/06/2026 03:05:00. 50 Economy ticket for £29 per person are available. Travel duration is 11h 45m
FlixBus	7h 20m	20:25	Milan	Lampugnano Bus Station	03:45	Karlsruhe	Central Station	Economy	£33	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 19/06/2026 20:25:00 to Central Station, Karlsruhe (Germany) arriving at 20/06/2026 03:45:00. 50 Economy ticket for £33 per person are available. Travel duration is 7h 20m
FlixBus	8h 20m	21:50	Milan	Lampugnano Bus Station	06:10	Karlsruhe	Central Station	Economy	£33	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 19/06/2026 21:50:00 to Central Station, Karlsruhe (Germany) arriving at 20/06/2026 06:10:00. 50 Economy ticket for £33 per person are available. Travel duration is 8h 20m
FlixBus	9h 55m	01:15	Milan	Lampugnano Bus Station	11:10	Karlsruhe	Central Station	Economy	£34	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 19/06/2026 01:15:00 to Central Station, Karlsruhe (Germany) arriving at 19/06/2026 11:10:00. 50 Economy ticket for £34 per person are available. Travel duration is 9h 55m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
BlaBlaCar Bus	11h 45m	15:20	Milan	Lampugnano Bus Station	03:05	Karlsruhe	Central Station	Economy	£29	A Bus from BlaBlaCar Bus goes from Lampugnano Bus Station, Milan (Italy) at 20/06/2026 15:20:00 to Central Station, Karlsruhe (Germany) arriving at 21/06/2026 03:05:00. 50 Economy ticket for £29 per person are available. Travel duration is 11h 45m
FlixBus	8h 10m	19:00	Milan	Lampugnano Bus Station	03:10	Karlsruhe	Central Station	Economy	£40	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 20/06/2026 19:00:00 to Central Station, Karlsruhe (Germany) arriving at 21/06/2026 03:10:00. 50 Economy ticket for £40 per person are available. Travel duration is 8h 10m
FlixBus	7h 20m	20:25	Milan	Lampugnano Bus Station	03:45	Karlsruhe	Central Station	Economy	£40	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 20/06/2026 20:25:00 to Central Station, Karlsruhe (Germany) arriving at 21/06/2026 03:45:00. 50 Economy ticket for £40 per person are available. Travel duration is 7h 20m
FlixBus	8h 20m	21:50	Milan	Lampugnano Bus Station	06:10	Karlsruhe	Central Station	Economy	£40	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 20/06/2026 21:50:00 to Central Station, Karlsruhe (Germany) arriving at 21/06/2026 06:10:00. 50 Economy ticket for £40 per person are available. Travel duration is 8h 20m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
BlaBlaCar Bus	11h 45m	15:20	Milan	Lampugnano Bus Station	03:05	Karlsruhe	Central Station	Economy	£32	A Bus from BlaBlaCar Bus goes from Lampugnano Bus Station, Milan (Italy) at 21/06/2026 15:20:00 to Central Station, Karlsruhe (Germany) arriving at 22/06/2026 03:05:00. 50 Economy ticket for £32 per person are available. Travel duration is 11h 45m
FlixBus	7h 20m	20:25	Milan	Lampugnano Bus Station	03:45	Karlsruhe	Central Station	Economy	£40	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 21/06/2026 20:25:00 to Central Station, Karlsruhe (Germany) arriving at 22/06/2026 03:45:00. 50 Economy ticket for £40 per person are available. Travel duration is 7h 20m
FlixBus	8h 20m	21:50	Milan	Lampugnano Bus Station	06:10	Karlsruhe	Central Station	Economy	£40	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 21/06/2026 21:50:00 to Central Station, Karlsruhe (Germany) arriving at 22/06/2026 06:10:00. 50 Economy ticket for £40 per person are available. Travel duration is 8h 20m
FlixBus	8h 10m	19:00	Milan	Lampugnano Bus Station	03:10	Karlsruhe	Central Station	Economy	£41	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 21/06/2026 19:00:00 to Central Station, Karlsruhe (Germany) arriving at 22/06/2026 03:10:00. 50 Economy ticket for £41 per person are available. Travel duration is 8h 10m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
BlaBlaCar Bus	11h 45m	15:20	Milan	Lampugnano Bus Station	03:05	Karlsruhe	Central Station	Economy	£27	A Bus from BlaBlaCar Bus goes from Lampugnano Bus Station, Milan (Italy) at 22/06/2026 15:20:00 to Central Station, Karlsruhe (Germany) arriving at 23/06/2026 03:05:00. 50 Economy ticket for £27 per person are available. Travel duration is 11h 45m
FlixBus	8h 20m	07:15	Milan	Lampugnano Bus Station	15:35	Karlsruhe	Central Station	Economy	£33	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 22/06/2026 07:15:00 to Central Station, Karlsruhe (Germany) arriving at 22/06/2026 15:35:00. 50 Economy ticket for £33 per person are available. Travel duration is 8h 20m
FlixBus	8h 40m	19:00	Milan	Lampugnano Bus Station	03:40	Karlsruhe	Central Station	Economy	£33	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 22/06/2026 19:00:00 to Central Station, Karlsruhe (Germany) arriving at 23/06/2026 03:40:00. 50 Economy ticket for £33 per person are available. Travel duration is 8h 40m
FlixBus	7h 50m	20:25	Milan	Lampugnano Bus Station	04:15	Karlsruhe	Central Station	Economy	£33	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 22/06/2026 20:25:00 to Central Station, Karlsruhe (Germany) arriving at 23/06/2026 04:15:00. 50 Economy ticket for £33 per person are available. Travel duration is 7h 50m

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	7h 50m	20:25	Milan	Lampugnano Bus Station	04:15	Karlsruhe	Central Station	Economy	£29	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 23/06/2026 20:25:00 to Central Station, Karlsruhe (Germany) arriving at 24/06/2026 04:15:00. 50 Economy ticket for £29 per person are available. Travel duration is 7h 50m
FlixBus	8h 20m	07:15	Milan	Lampugnano Bus Station	15:35	Karlsruhe	Central Station	Economy	£30	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 23/06/2026 07:15:00 to Central Station, Karlsruhe (Germany) arriving at 23/06/2026 15:35:00. 50 Economy ticket for £30 per person are available. Travel duration is 8h 20m
FlixBus	8h 40m	19:00	Milan	Lampugnano Bus Station	03:40	Karlsruhe	Central Station	Economy	£30	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 23/06/2026 19:00:00 to Central Station, Karlsruhe (Germany) arriving at 24/06/2026 03:40:00. 50 Economy ticket for £30 per person are available. Travel duration is 8h 40m
FlixBus	9h 5m	23:45	Milan	Lampugnano Bus Station	08:50	Karlsruhe	Central Station	Economy	£30	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 23/06/2026 23:45:00 to Central Station, Karlsruhe (Germany) arriving at 24/06/2026 08:50:00. 50 Economy ticket for £30 per person are available. Travel duration is 9h 5m
FlixBus	9h 55m	01:15	Milan	Lampugnano Bus Station	11:10	Karlsruhe	Central Station	Economy	£31	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 23/06/2026 01:15:00 to Central Station, Karlsruhe (Germany) arriving at 23/06/2026 11:10:00. 50 Economy ticket for £31 per person are available. Travel duration is 9h 55m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	8h 20m	07:15	Milan	Lampugnano Bus Station	15:35	Karlsruhe	Central Station	Economy	£28	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 24/06/2026 07:15:00 to Central Station, Karlsruhe (Germany) arriving at 24/06/2026 15:35:00. 50 Economy ticket for £28 per person are available. Travel duration is 8h 20m
FlixBus	7h 50m	20:25	Milan	Lampugnano Bus Station	04:15	Karlsruhe	Central Station	Economy	£28	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 24/06/2026 20:25:00 to Central Station, Karlsruhe (Germany) arriving at 25/06/2026 04:15:00. 50 Economy ticket for £28 per person are available. Travel duration is 7h 50m
FlixBus	8h 20m	21:50	Milan	Lampugnano Bus Station	06:10	Karlsruhe	Central Station	Economy	£29	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 24/06/2026 21:50:00 to Central Station, Karlsruhe (Germany) arriving at 25/06/2026 06:10:00. 50 Economy ticket for £29 per person are available. Travel duration is 8h 20m
BlaBlaCar Bus	17h 50m	17:00	Milan	Lampugnano Bus Station	10:50	Karlsruhe	Central Station	Economy	£33	A Bus from BlaBlaCar Bus goes from Lampugnano Bus Station, Milan (Italy) at 24/06/2026 17:00:00 to Central Station, Karlsruhe (Germany) arriving at 25/06/2026 10:50:00. 50 Economy ticket for £33 per person are available. Travel duration is 17h 50m

Best Price Offer: The price for the cheapest coach from Milan to Karlsruhe is £27 on 22/06/2026. Flexible travellers save on ticket prices.

Frequency of bus connections between Milan and Karlsruhe

See here how frequent the connections between Milan and Karlsruhe are, during different times and days of the week.

Friday is the busiest day, with more than 8 daily coaches from Milan to Karlsruhe. Tuesday has instead the fewest connections, with only 5 daily coaches between Milan and Karlsruhe.

The busiest time of the day is the Evening, with 26 coaches from Milan to Karlsruhe, while Afternoon sees the fewest connections between Milan and Karlsruhe, with 5 offers.

Facts about coaches from Milan to Karlsruhe

Compare all providers like FlixBus and BlaBlaCar Bus that travel 7 times every day by bus from Milan to Karlsruhe in one click! Book your bus ticket from Milan to Karlsruhe starting from £27!

Cheapest Bus	£27
Fastest Bus	7h 20m
Earliest Coach	01:15
Latest Coach	23:45
Daily Bus Connections	7 Ø
Distance	398.2 km
Coach Companies	FlixBus and BlaBlaCar Bus

Cheapest coach connections from Milan to Karlsruhe

Every day, 7 buses from 2 coach companies leave Milan for Karlsruhe: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 18/06/2026 and for the following days.

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday

Monday 15/06

Tuesday 16/06

Wednesday 17/06

Thursday 18/06

£30

Friday 19/06

£33

Saturday 20/06

£40

Sunday 21/06

£40

Monday 22/06

£33

Tuesday 23/06

£29

Wednesday 24/06

£29

Thursday 25/06

£29

Friday 26/06

£35

Saturday 27/06

£36

Sunday 28/06

£33

Monday 29/06

£31

Tuesday 30/06

£29

Wednesday 01/07

£29

Thursday 02/07

£29

Friday 03/07

£34

Saturday 04/07

£34

Sunday 05/07

£34

Monday 06/07

£30

Tuesday 07/07

£28

Wednesday 08/07

£29

Thursday 09/07

£29

Friday 10/07

£69

Saturday 11/07

£33

Sunday 12/07

The cheapest time to travel from Milan to Karlsruhe

See here on which day and which time of the day you can find the cheapest bus ticket from Milan to Karlsruhe, for the next 30 days.

With a price starting from £27, Monday is the cheapest day for a coach from Milan to Karlsruhe. Sunday instead is the most expensive day with prices starting from £32.

Afternoon is the cheapest day time for bus tickets from Milan to Karlsruhe, with £27. Morning is the most expensive time of the day with prices starting from £28.

How to save money travelling from Milan to Karlsruhe

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Milan to Karlsruhe in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Milan to Karlsruhe, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Milan to Karlsruhe are also emptier.

All bus stations and stops in Milan and Karlsruhe

The map below shows you where to find all the bus stations in Milan and Karlsruhe.

Lampugnano Bus Station

Via Giulio Natta Lampugnano

Rogoredo Bus Station

Via Cassinis Giovanni Battista 76

San Donato Bus Station

Via Giuseppe Impastato 25

Central Station - Piazza Luigi di Savoia

Piazza Duca D'Aosta 16

Duomo Bus Stop

Piazza del Duomo

Central Bus Station

Central Station

Hinterm Hauptbahnhof 6

Durlach Train Station

Knielingen Train Station

Durlach Auer Str./Dr.Willmar Schwabe Bus Stop

Service and Comfort on the bus from Milan to Karlsruhe

Want to know which seat classes are available on the coaches from Milan to Karlsruhe? Or which bus companies serve the route Milan to Karlsruhe? Below you will find answers to your questions.

FAQs about the Milan to Karlsruhe bus

How much does a Milan - Karlsruhe coach trip cost?

This depends on, among other things, the day and travel time. The cheapest ticket for the Milan - Karlsruhe bus trip is available from £27 and takes 11h 45m. Compare offers and save money!

How much could I save by comparing buses from Milan to Karlsruhe?

The connection Milan to Karlsruhe is offered by 2 companies with ticket prices ranging from £27 to £54. Therefore, we suggest booking your ticket as soon as possible to ensure you will get the cheapest ticket price.

How many connections are available for the Milan - Karlsruhe route on average every day?

Each day, the bus route from Milan to Karlsruhe is offered by roughly 7 busses. By using our search, you can compare bus schedules and find your ideal trip.

How long does a bus to Karlsruhe from Milan take?

The quickest coach from Milan to Karlsruhe is provided by FlixBus and takes 7h 20m. Coach tickets for this connection cost £33. However, keep in mind that the connection can take longer due to traffic.

What time is the first bus from Milan to Karlsruhe?

The earliest bus to Karlsruhe departs from Milan at 01:15. In this context, information about departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

What time is the last coach from Milan to Karlsruhe?

The latest bus to Karlsruhe departs from Milan at 23:45. Please note that departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

Which bus companies serve the Milan - Karlsruhe route?

Passengers looking to travel from Milan to Karlsruhe can travel with FlixBus and BlaBlaCar Bus. Compare all available bus tickets with our search to book the trip that works best for you.

Is there a direct bus between Milan and Karlsruhe?

You can check all the direct connections between Milan and Karlsruhe by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and BlaBlaCar Bus.

What can I take with me on the bus to Karlsruhe from Milan?

Depending on which provider you travel with, what you are allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the bus for the Milan Karlsruhe bus route free of charge. Simply use our search to find a coach that is best suited to your needs for your planned travel date.

What equipment is available for the Milan Karlsruhe bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make travelling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Milan to Karlsruhe on your planned travel date.

How does CheckMyBus find the best bus deals from Milan to Karlsruhe?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 7 daily trips between Milan and Karlsruhe. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Milan to Karlsruhe?

Prices and availability for 7 trips between Milan and Karlsruhe change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Milan to Karlsruhe

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Milan and to Karlsruhe

Here’s an overview of the most popular bus routes to Milan and to Karlsruhe. Simply click on the connection of your choice, and you will find all the details about your bus route!