Which bus from Mexico City to San Diego is the best?
Check the bus schedule for Mexico City to San Diego. Here is a selection of the cheapest coach trips for the next days from bus operators like Flix Mexico. To see the full timetable for all coaches just use or search and compare.
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Flix Mexico | 64h 50m | 22:50 | Mexico City | San Pedro Santa Clara Coach Stop | 14:40 | San Diego | San Ysidro Transit Center | Economy | £175 |
A Bus from Flix Mexico goes from San Pedro Santa Clara Coach Stop, Mexico City (Mexico) at 06/03/2026 22:50:00 to San Ysidro Transit Center, San Diego (USA) arriving at 09/03/2026 14:40:00. 50 Economy ticket for £175 per person are available. Travel duration is 64h 50m
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| Flix Mexico | 64h 10m | 23:30 | Mexico City | Fórum Buenavista | 14:40 | San Diego | San Ysidro Transit Center | Economy | £175 |
A Bus from Flix Mexico goes from Fórum Buenavista, Mexico City (Mexico) at 06/03/2026 23:30:00 to San Ysidro Transit Center, San Diego (USA) arriving at 09/03/2026 14:40:00. 50 Economy ticket for £175 per person are available. Travel duration is 64h 10m
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| Flix Mexico | 67h 50m | 15:45 | Mexico City | San Pedro Santa Clara Coach Stop | 10:35 | San Diego | San Ysidro Transit Center | Economy | £196 |
A Bus from Flix Mexico goes from San Pedro Santa Clara Coach Stop, Mexico City (Mexico) at 06/03/2026 15:45:00 to San Ysidro Transit Center, San Diego (USA) arriving at 09/03/2026 10:35:00. 50 Economy ticket for £196 per person are available. Travel duration is 67h 50m
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| Flix Mexico | 67h 25m | 16:10 | Mexico City | Fórum Buenavista | 10:35 | San Diego | San Ysidro Transit Center | Economy | £196 |
A Bus from Flix Mexico goes from Fórum Buenavista, Mexico City (Mexico) at 06/03/2026 16:10:00 to San Ysidro Transit Center, San Diego (USA) arriving at 09/03/2026 10:35:00. 50 Economy ticket for £196 per person are available. Travel duration is 67h 25m
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ACN Autobuses80h 5m022:30Mexico CityInstituto Politécnico Nacional Coach Stop16:33Tijuana, BCCentro Coach Stop0EconomyA Bus from ACN Autobuses goes from Instituto Politécnico Nacional Coach Stop, Mexico City (Mexico) at 07/03/2026 22:30:00 to Centro Coach Stop, Tijuana, BC (Mexico) arriving at 09/03/2026 16:33:00. 50 Economy ticket for £93 per person are available. Travel duration is 43h 3m
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Greyhound US1h 15m004:20Tijuana, BCCentral Coach Station05:35San DiegoSan Ysidro Transit Center0EconomyA Bus from Greyhound US goes from Central Coach Station, Tijuana, BC (Mexico) at 11/03/2026 04:20:00 to San Ysidro Transit Center, San Diego (USA) arriving at 11/03/2026 05:35:00. 50 Economy ticket for £3 per person are available. Travel duration is 1h 15m
Waiting Time 35h 47m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Flix Mexico | 72h 15m | 23:30 | Mexico City | Fórum Buenavista | 22:45 | San Diego | San Ysidro Transit Center | Economy | £164 |
A Bus from Flix Mexico goes from Fórum Buenavista, Mexico City (Mexico) at 07/03/2026 23:30:00 to San Ysidro Transit Center, San Diego (USA) arriving at 10/03/2026 22:45:00. 50 Economy ticket for £164 per person are available. Travel duration is 72h 15m
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| Flix Mexico | 68h 55m | 22:25 | Mexico City | Fórum Buenavista | 18:20 | San Diego | San Ysidro Transit Center | Economy | £169 |
A Bus from Flix Mexico goes from Fórum Buenavista, Mexico City (Mexico) at 07/03/2026 22:25:00 to San Ysidro Transit Center, San Diego (USA) arriving at 10/03/2026 18:20:00. 50 Economy ticket for £169 per person are available. Travel duration is 68h 55m
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| Flix Mexico | 67h 25m | 16:10 | Mexico City | Fórum Buenavista | 10:35 | San Diego | San Ysidro Transit Center | Economy | £171 |
A Bus from Flix Mexico goes from Fórum Buenavista, Mexico City (Mexico) at 07/03/2026 16:10:00 to San Ysidro Transit Center, San Diego (USA) arriving at 10/03/2026 10:35:00. 50 Economy ticket for £171 per person are available. Travel duration is 67h 25m
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ACN Autobuses80h 5m022:30Mexico CityInstituto Politécnico Nacional Coach Stop16:33Tijuana, BCCentro Coach Stop0EconomyA Bus from ACN Autobuses goes from Instituto Politécnico Nacional Coach Stop, Mexico City (Mexico) at 07/03/2026 22:30:00 to Centro Coach Stop, Tijuana, BC (Mexico) arriving at 09/03/2026 16:33:00. 50 Economy ticket for £93 per person are available. Travel duration is 43h 3m
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Greyhound US1h 15m004:20Tijuana, BCCentral Coach Station05:35San DiegoSan Ysidro Transit Center0EconomyA Bus from Greyhound US goes from Central Coach Station, Tijuana, BC (Mexico) at 11/03/2026 04:20:00 to San Ysidro Transit Center, San Diego (USA) arriving at 11/03/2026 05:35:00. 50 Economy ticket for £3 per person are available. Travel duration is 1h 15m
Waiting Time 35h 47m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Flix Mexico | 69h 45m | 22:00 | Mexico City | San Pedro Santa Clara Coach Stop | 18:45 | San Diego | San Ysidro Transit Center | Economy | £162 |
A Bus from Flix Mexico goes from San Pedro Santa Clara Coach Stop, Mexico City (Mexico) at 08/03/2026 22:00:00 to San Ysidro Transit Center, San Diego (USA) arriving at 11/03/2026 18:45:00. 50 Economy ticket for £162 per person are available. Travel duration is 69h 45m
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| Flix Mexico | 69h 20m | 22:25 | Mexico City | Fórum Buenavista | 18:45 | San Diego | San Ysidro Transit Center | Economy | £162 |
A Bus from Flix Mexico goes from Fórum Buenavista, Mexico City (Mexico) at 08/03/2026 22:25:00 to San Ysidro Transit Center, San Diego (USA) arriving at 11/03/2026 18:45:00. 50 Economy ticket for £162 per person are available. Travel duration is 69h 20m
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| Flix Mexico | 72h 55m | 22:50 | Mexico City | San Pedro Santa Clara Coach Stop | 22:45 | San Diego | San Ysidro Transit Center | Economy | £170 |
A Bus from Flix Mexico goes from San Pedro Santa Clara Coach Stop, Mexico City (Mexico) at 08/03/2026 22:50:00 to San Ysidro Transit Center, San Diego (USA) arriving at 11/03/2026 22:45:00. 50 Economy ticket for £170 per person are available. Travel duration is 72h 55m
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| Flix Mexico | 72h 15m | 23:30 | Mexico City | Fórum Buenavista | 22:45 | San Diego | San Ysidro Transit Center | Economy | £170 |
A Bus from Flix Mexico goes from Fórum Buenavista, Mexico City (Mexico) at 08/03/2026 23:30:00 to San Ysidro Transit Center, San Diego (USA) arriving at 11/03/2026 22:45:00. 50 Economy ticket for £170 per person are available. Travel duration is 72h 15m
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| Flix Mexico | 69h 35m | 15:45 | Mexico City | San Pedro Santa Clara Coach Stop | 12:20 | San Diego | San Ysidro Transit Center | Economy | £181 |
A Bus from Flix Mexico goes from San Pedro Santa Clara Coach Stop, Mexico City (Mexico) at 08/03/2026 15:45:00 to San Ysidro Transit Center, San Diego (USA) arriving at 11/03/2026 12:20:00. 50 Economy ticket for £181 per person are available. Travel duration is 69h 35m
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ACN Autobuses80h 5m022:30Mexico CityInstituto Politécnico Nacional Coach Stop16:33Tijuana, BCCentro Coach Stop0EconomyA Bus from ACN Autobuses goes from Instituto Politécnico Nacional Coach Stop, Mexico City (Mexico) at 07/03/2026 22:30:00 to Centro Coach Stop, Tijuana, BC (Mexico) arriving at 09/03/2026 16:33:00. 50 Economy ticket for £93 per person are available. Travel duration is 43h 3m
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Greyhound US1h 15m004:20Tijuana, BCCentral Coach Station05:35San DiegoSan Ysidro Transit Center0EconomyA Bus from Greyhound US goes from Central Coach Station, Tijuana, BC (Mexico) at 11/03/2026 04:20:00 to San Ysidro Transit Center, San Diego (USA) arriving at 11/03/2026 05:35:00. 50 Economy ticket for £3 per person are available. Travel duration is 1h 15m
Waiting Time 35h 47m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Flix Mexico | 64h 50m | 22:50 | Mexico City | San Pedro Santa Clara Coach Stop | 14:40 | San Diego | San Ysidro Transit Center | Economy | £162 |
A Bus from Flix Mexico goes from San Pedro Santa Clara Coach Stop, Mexico City (Mexico) at 11/03/2026 22:50:00 to San Ysidro Transit Center, San Diego (USA) arriving at 14/03/2026 14:40:00. 50 Economy ticket for £162 per person are available. Travel duration is 64h 50m
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| Flix Mexico | 64h 10m | 23:30 | Mexico City | Fórum Buenavista | 14:40 | San Diego | San Ysidro Transit Center | Economy | £162 |
A Bus from Flix Mexico goes from Fórum Buenavista, Mexico City (Mexico) at 11/03/2026 23:30:00 to San Ysidro Transit Center, San Diego (USA) arriving at 14/03/2026 14:40:00. 50 Economy ticket for £162 per person are available. Travel duration is 64h 10m
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| Flix Mexico | 72h 0m | 11:35 | Mexico City | San Pedro Santa Clara Coach Stop | 10:35 | San Diego | San Ysidro Transit Center | Economy | £168 |
A Bus from Flix Mexico goes from San Pedro Santa Clara Coach Stop, Mexico City (Mexico) at 11/03/2026 11:35:00 to San Ysidro Transit Center, San Diego (USA) arriving at 14/03/2026 10:35:00. 50 Economy ticket for £168 per person are available. Travel duration is 72h 0m
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| Flix Mexico | 71h 35m | 12:00 | Mexico City | Fórum Buenavista | 10:35 | San Diego | San Ysidro Transit Center | Economy | £168 |
A Bus from Flix Mexico goes from Fórum Buenavista, Mexico City (Mexico) at 11/03/2026 12:00:00 to San Ysidro Transit Center, San Diego (USA) arriving at 14/03/2026 10:35:00. 50 Economy ticket for £168 per person are available. Travel duration is 71h 35m
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ACN Autobuses56h 5m022:30Mexico CityInstituto Politécnico Nacional Coach Stop15:03Tijuana, BCBuena Vista0EconomyA Bus from ACN Autobuses goes from Instituto Politécnico Nacional Coach Stop, Mexico City (Mexico) at 12/03/2026 22:30:00 to Buena Vista, Tijuana, BC (Mexico) arriving at 14/03/2026 15:03:00. 50 Economy ticket for £94 per person are available. Travel duration is 41h 33m
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Greyhound US1h 15m004:20Tijuana, BCCentral Coach Station05:35San DiegoSan Ysidro Transit Center0EconomyA Bus from Greyhound US goes from Central Coach Station, Tijuana, BC (Mexico) at 15/03/2026 04:20:00 to San Ysidro Transit Center, San Diego (USA) arriving at 15/03/2026 05:35:00. 50 Economy ticket for £4 per person are available. Travel duration is 1h 15m
Waiting Time 13h 17m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Flix Mexico | 64h 50m | 22:50 | Mexico City | San Pedro Santa Clara Coach Stop | 14:40 | San Diego | San Ysidro Transit Center | Economy | £165 |
A Bus from Flix Mexico goes from San Pedro Santa Clara Coach Stop, Mexico City (Mexico) at 12/03/2026 22:50:00 to San Ysidro Transit Center, San Diego (USA) arriving at 15/03/2026 14:40:00. 50 Economy ticket for £165 per person are available. Travel duration is 64h 50m
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| Flix Mexico | 64h 10m | 23:30 | Mexico City | Fórum Buenavista | 14:40 | San Diego | San Ysidro Transit Center | Economy | £165 |
A Bus from Flix Mexico goes from Fórum Buenavista, Mexico City (Mexico) at 12/03/2026 23:30:00 to San Ysidro Transit Center, San Diego (USA) arriving at 15/03/2026 14:40:00. 50 Economy ticket for £165 per person are available. Travel duration is 64h 10m
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| Flix Mexico | 67h 50m | 15:45 | Mexico City | San Pedro Santa Clara Coach Stop | 10:35 | San Diego | San Ysidro Transit Center | Economy | £171 |
A Bus from Flix Mexico goes from San Pedro Santa Clara Coach Stop, Mexico City (Mexico) at 12/03/2026 15:45:00 to San Ysidro Transit Center, San Diego (USA) arriving at 15/03/2026 10:35:00. 50 Economy ticket for £171 per person are available. Travel duration is 67h 50m
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| Flix Mexico | 67h 25m | 16:10 | Mexico City | Fórum Buenavista | 10:35 | San Diego | San Ysidro Transit Center | Economy | £171 |
A Bus from Flix Mexico goes from Fórum Buenavista, Mexico City (Mexico) at 12/03/2026 16:10:00 to San Ysidro Transit Center, San Diego (USA) arriving at 15/03/2026 10:35:00. 50 Economy ticket for £171 per person are available. Travel duration is 67h 25m
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ACN Autobuses56h 5m022:30Mexico CityInstituto Politécnico Nacional Coach Stop15:03Tijuana, BCBuena Vista0EconomyA Bus from ACN Autobuses goes from Instituto Politécnico Nacional Coach Stop, Mexico City (Mexico) at 12/03/2026 22:30:00 to Buena Vista, Tijuana, BC (Mexico) arriving at 14/03/2026 15:03:00. 50 Economy ticket for £94 per person are available. Travel duration is 41h 33m
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Greyhound US1h 15m004:20Tijuana, BCCentral Coach Station05:35San DiegoSan Ysidro Transit Center0EconomyA Bus from Greyhound US goes from Central Coach Station, Tijuana, BC (Mexico) at 15/03/2026 04:20:00 to San Ysidro Transit Center, San Diego (USA) arriving at 15/03/2026 05:35:00. 50 Economy ticket for £4 per person are available. Travel duration is 1h 15m
Waiting Time 13h 17m -
Best Price Offer: The price for the cheapest coach from Mexico City to San Diego is £162 on 08/03/2026. Flexible travellers save on ticket prices.
What is the best day and time to travel by bus between Mexico City and San Diego?
All facts for Mexico City to San Diego bus at a glance
Compare all coach operators like Flix Mexico that travel daily 4 times by bus from Mexico City to San Diego in one click. Book your Mexico City to San Diego bus ticket starting from £162!
| Cheapest Bus | £162 |
| Fastest Bus | 63h 10m |
| Earliest Coach | 15:45 |
| Latest Coach | 23:30 |
| Daily Bus Connections | 4 Ø |
| Distance | 2,322.0 km |
| Coach Companies | Flix Mexico |
What are the cheapest coach tickets from Mexico City to San Diego?
Every day, 4 buses from 1 coach companies leave Mexico City for San Diego. Check the table below to find the cheapest prices for coach tickets for this route, starting from 06/03/2026 and for the following days. Make sure get the cheapest bus ticket!
The cheapest time to travel from Mexico City to San Diego
How to save money travelling from Mexico City to San Diego
Book the ticket from Mexico City to San Diego in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the coach from Mexico City to San Diego, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Mexico City to San Diego are also emptier.Check for bus deals and promotions for all bus companies in this route. On CheckMyBus we show special offers directly in the coach trip on our search. Sign-up and check or deals sections and get notifications on our latest travel hacks.
All bus stations and stops in Mexico City and San Diego
Here is a map with all coach stations in Mexico City and San Diego. Compare which stop is closest to your destination to save time to find the fastest buses and connections.
Compare the bus with other modes of transport
All you need to know when you travel by bus from Mexico City to San Diego
FAQs for Mexico City to San Diego bus
How much does a Mexico City San Diego coach trip cost?
How much could I save by comparing buses from Mexico City to San Diego?
How many connections are available for the Mexico City San Diego route on average every day?
How long does a bus to San Diego from Mexico City take?
What time is the first bus from Mexico City to San Diego?
What time is the last coach from Mexico City to San Diego?
Which bus companies serve the Mexico City San Diego route?
Is there a direct bus between Mexico City and San Diego?
What can I take with me on the bus to San Diego from Mexico City?
What equipment is available for the Mexico City San Diego bus route?
How does CheckMyBus find the best coach deals from Mexico City to San Diego?
How does CheckMyBus technology work for trips from Mexico City to San Diego?
Available seat classes which are offered on the bus route Mexico City to San Diego
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
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