Bus and Coach from San Francisco to San Diego: Compare all prices

Compare all timetables for the bus from San Francisco to San Diego

Here is a selection of the cheapest bus trips from the schedule from San Francisco to San Diego from various bus operators like Greyhound US or FlixBus for the next days.

today

£52

tomorrow

£47

Friday

£51

Saturday

£59

Sunday

£57

Monday

£44

Tuesday

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	26h 20m	16:00	San Francisco	Salesforce Transit Center	18:20	San Diego	San Ysidro Transit Center	Economy	£52	A Bus from Greyhound US goes from Salesforce Transit Center, San Francisco (USA) at 12/08/2026 16:00:00 to San Ysidro Transit Center, San Diego (USA) arriving at 13/08/2026 18:20:00. 50 Economy ticket for £52 per person are available. Travel duration is 26h 20m
FlixBus	16h 40m	07:10	San Francisco	5th/Townsend	23:50	San Diego	Old Town Transit Center	Economy	£65	A Bus from FlixBus goes from 5th/Townsend, San Francisco (USA) at 12/08/2026 07:10:00 to Old Town Transit Center, San Diego (USA) arriving at 12/08/2026 23:50:00. 50 Economy ticket for £65 per person are available. Travel duration is 16h 40m
FlixBus	15h 5m	07:10	San Francisco	5th/Townsend	22:15	San Diego	Seaport Village	Economy	£66	A Bus from FlixBus goes from 5th/Townsend, San Francisco (USA) at 12/08/2026 07:10:00 to Seaport Village, San Diego (USA) arriving at 12/08/2026 22:15:00. 50 Economy ticket for £66 per person are available. Travel duration is 15h 5m
FlixBus	14h 35m	07:10	San Francisco	5th/Townsend	21:45	San Diego	La Jolla Village	Economy	£68	A Bus from FlixBus goes from 5th/Townsend, San Francisco (USA) at 12/08/2026 07:10:00 to La Jolla Village, San Diego (USA) arriving at 12/08/2026 21:45:00. 50 Economy ticket for £68 per person are available. Travel duration is 14h 35m
Greyhound US	24h 25m	16:00	San Francisco	Salesforce Transit Center	16:25	San Diego	Old Town Transit Center	Economy	£78	A Bus from Greyhound US goes from Salesforce Transit Center, San Francisco (USA) at 12/08/2026 16:00:00 to Old Town Transit Center, San Diego (USA) arriving at 13/08/2026 16:25:00. 50 Economy ticket for £78 per person are available. Travel duration is 24h 25m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	14h 35m	07:10	San Francisco	5th/Townsend	21:45	San Diego	La Jolla Village	Economy	£47	A Bus from FlixBus goes from 5th/Townsend, San Francisco (USA) at 13/08/2026 07:10:00 to La Jolla Village, San Diego (USA) arriving at 13/08/2026 21:45:00. 50 Economy ticket for £47 per person are available. Travel duration is 14h 35m
FlixBus	15h 5m	07:10	San Francisco	5th/Townsend	22:15	San Diego	Seaport Village	Economy	£47	A Bus from FlixBus goes from 5th/Townsend, San Francisco (USA) at 13/08/2026 07:10:00 to Seaport Village, San Diego (USA) arriving at 13/08/2026 22:15:00. 50 Economy ticket for £47 per person are available. Travel duration is 15h 5m
FlixBus	16h 40m	07:10	San Francisco	5th/Townsend	23:50	San Diego	Old Town Transit Center	Economy	£47	A Bus from FlixBus goes from 5th/Townsend, San Francisco (USA) at 13/08/2026 07:10:00 to Old Town Transit Center, San Diego (USA) arriving at 13/08/2026 23:50:00. 50 Economy ticket for £47 per person are available. Travel duration is 16h 40m
Greyhound US	24h 25m	16:00	San Francisco	Bus Station Transbay	16:25	San Diego	Old Town Transit Center	Economy	£51	A Bus from Greyhound US goes from Bus Station Transbay, San Francisco (USA) at 13/08/2026 16:00:00 to Old Town Transit Center, San Diego (USA) arriving at 14/08/2026 16:25:00. 50 Economy ticket for £51 per person are available. Travel duration is 24h 25m
Greyhound US	23h 55m	16:00	San Francisco	Bus Station Transbay	15:55	San Diego	La Jolla Village	Economy	£51	A Bus from Greyhound US goes from Bus Station Transbay, San Francisco (USA) at 13/08/2026 16:00:00 to La Jolla Village, San Diego (USA) arriving at 14/08/2026 15:55:00. 50 Economy ticket for £51 per person are available. Travel duration is 23h 55m

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	24h 25m	16:00	San Francisco	Salesforce Transit Center	16:25	San Diego	Old Town Transit Center	Economy	£51	A Bus from Greyhound US goes from Salesforce Transit Center, San Francisco (USA) at 14/08/2026 16:00:00 to Old Town Transit Center, San Diego (USA) arriving at 15/08/2026 16:25:00. 50 Economy ticket for £51 per person are available. Travel duration is 24h 25m
FlixBus	17h 0m	23:25	San Francisco	5th/Townsend	16:25	San Diego	Old Town Transit Center	Economy	£51	A Bus from FlixBus goes from 5th/Townsend, San Francisco (USA) at 14/08/2026 23:25:00 to Old Town Transit Center, San Diego (USA) arriving at 15/08/2026 16:25:00. 50 Economy ticket for £51 per person are available. Travel duration is 17h 0m
Greyhound US	13h 5m	22:40	San Francisco	Salesforce Transit Center	11:45	San Diego	Old Town Transit Center	Economy	£62	A Bus from Greyhound US goes from Salesforce Transit Center, San Francisco (USA) at 14/08/2026 22:40:00 to Old Town Transit Center, San Diego (USA) arriving at 15/08/2026 11:45:00. 50 Economy ticket for £62 per person are available. Travel duration is 13h 5m
Greyhound US	26h 20m	16:00	San Francisco	Bus Station Transbay	18:20	San Diego	San Ysidro Transit Center	Economy	£64	A Bus from Greyhound US goes from Bus Station Transbay, San Francisco (USA) at 14/08/2026 16:00:00 to San Ysidro Transit Center, San Diego (USA) arriving at 15/08/2026 18:20:00. 50 Economy ticket for £64 per person are available. Travel duration is 26h 20m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	26h 20m	16:00	San Francisco	Salesforce Transit Center	18:20	San Diego	San Ysidro Transit Center	Economy	£59	A Bus from Greyhound US goes from Salesforce Transit Center, San Francisco (USA) at 15/08/2026 16:00:00 to San Ysidro Transit Center, San Diego (USA) arriving at 16/08/2026 18:20:00. 50 Economy ticket for £59 per person are available. Travel duration is 26h 20m
Greyhound US	17h 20m	06:30	San Francisco	Salesforce Transit Center	23:50	San Diego	Old Town Transit Center	Economy	£63	A Bus from Greyhound US goes from Salesforce Transit Center, San Francisco (USA) at 15/08/2026 06:30:00 to Old Town Transit Center, San Diego (USA) arriving at 15/08/2026 23:50:00. 50 Economy ticket for £63 per person are available. Travel duration is 17h 20m
Greyhound US	24h 25m	16:00	San Francisco	Salesforce Transit Center	16:25	San Diego	Old Town Transit Center	Economy	£79	A Bus from Greyhound US goes from Salesforce Transit Center, San Francisco (USA) at 15/08/2026 16:00:00 to Old Town Transit Center, San Diego (USA) arriving at 16/08/2026 16:25:00. 50 Economy ticket for £79 per person are available. Travel duration is 24h 25m
Greyhound US	13h 15m	22:30	San Francisco	Salesforce Transit Center	11:45	San Diego	Old Town Transit Center	Economy	£142	A Bus from Greyhound US goes from Salesforce Transit Center, San Francisco (USA) at 15/08/2026 22:30:00 to Old Town Transit Center, San Diego (USA) arriving at 16/08/2026 11:45:00. 50 Economy ticket for £142 per person are available. Travel duration is 13h 15m

Did you know that if you travel from San Francisco to San Diego via Oakland, you can save more than £4? You will find the corresponding connections below.
- Save more than 7%
  
  23h 20m
  
  San Francisco
  
  12 km
  
  16:35
  
  Oakland
  W Oakland BART Station
  
  15:55
  
  San Diego
  La Jolla Village
  
  0 km
  
  Economy
  
  £55
  
  A Bus from goes from W Oakland BART Station, Oakland (USA) at 15/08/2026 16:35:00 to La Jolla Village, San Diego (USA) arriving at 16/08/2026 15:55:00. 50 Economy ticket for £55 per person are available. Travel duration is 23h 20m
Did you know that if you travel from San Francisco to San Diego via San Jose, CA, you can save more than £18? You can find the corresponding connections below.
- FlixBus
  
  15h 5m
  
  0
  
  07:10
  
  San Francisco
  5th/Townsend
  
  08:05
  
  San Jose, CA
  Bus Stop
  
  0
  
  Economy
  
  £7
  
  A Bus from FlixBus goes from 5th/Townsend, San Francisco (USA) at 17/08/2026 07:10:00 to Bus Stop, San Jose, CA (USA) arriving at 17/08/2026 08:05:00. 50 Economy ticket for £7 per person are available. Travel duration is 0h 55m
- FlixBus
  
  14h 0m
  
  0
  
  08:15
  
  San Jose, CA
  Bus Stop
  
  22:15
  
  San Diego
  Seaport Village
  
  0
  
  Economy
  
  £34
  
  A Bus from FlixBus goes from Bus Stop, San Jose, CA (USA) at 17/08/2026 08:15:00 to Seaport Village, San Diego (USA) arriving at 17/08/2026 22:15:00. 50 Economy ticket for £34 per person are available. Travel duration is 14h 0m
Travel time is 1h 50m longer, but you will save £18

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	24h 25m	16:00	San Francisco	Salesforce Transit Center	16:25	San Diego	Old Town Transit Center	Economy	£57	A Bus from Greyhound US goes from Salesforce Transit Center, San Francisco (USA) at 16/08/2026 16:00:00 to Old Town Transit Center, San Diego (USA) arriving at 17/08/2026 16:25:00. 50 Economy ticket for £57 per person are available. Travel duration is 24h 25m
Greyhound US	23h 55m	16:00	San Francisco	Bus Station Transbay	15:55	San Diego	La Jolla Village	Economy	£60	A Bus from Greyhound US goes from Bus Station Transbay, San Francisco (USA) at 16/08/2026 16:00:00 to La Jolla Village, San Diego (USA) arriving at 17/08/2026 15:55:00. 50 Economy ticket for £60 per person are available. Travel duration is 23h 55m
Greyhound US	26h 20m	16:00	San Francisco	Bus Station Transbay	18:20	San Diego	San Ysidro Transit Center	Economy	£66	A Bus from Greyhound US goes from Bus Station Transbay, San Francisco (USA) at 16/08/2026 16:00:00 to San Ysidro Transit Center, San Diego (USA) arriving at 17/08/2026 18:20:00. 50 Economy ticket for £66 per person are available. Travel duration is 26h 20m
Greyhound US	17h 20m	06:30	San Francisco	Salesforce Transit Center	23:50	San Diego	Old Town Transit Center	Economy	£83	A Bus from Greyhound US goes from Salesforce Transit Center, San Francisco (USA) at 16/08/2026 06:30:00 to Old Town Transit Center, San Diego (USA) arriving at 16/08/2026 23:50:00. 50 Economy ticket for £83 per person are available. Travel duration is 17h 20m
Greyhound US	17h 55m	06:30	San Francisco	Bus Station Transbay	00:25	San Diego	San Ysidro Transit Center	Economy	£90	A Bus from Greyhound US goes from Bus Station Transbay, San Francisco (USA) at 16/08/2026 06:30:00 to San Ysidro Transit Center, San Diego (USA) arriving at 17/08/2026 00:25:00. 50 Economy ticket for £90 per person are available. Travel duration is 17h 55m

Did you know that if you travel from San Francisco to San Diego via Oakland, you can save more than £-7? You will find the corresponding connections below.
- 16h 50m
  
  San Francisco
  
  12 km
  
  07:00
  
  Oakland
  W Oakland BART Station
  
  23:50
  
  San Diego
  Old Town Transit Center
  
  0 km
  
  Economy
  
  £64
  
  A Bus from goes from W Oakland BART Station, Oakland (USA) at 16/08/2026 07:00:00 to Old Town Transit Center, San Diego (USA) arriving at 16/08/2026 23:50:00. 50 Economy ticket for £64 per person are available. Travel duration is 16h 50m
Did you know that if you travel from San Francisco to San Diego via San Jose, CA, you can save more than £16? You can find the corresponding connections below.
- FlixBus
  
  15h 5m
  
  0
  
  07:10
  
  San Francisco
  5th/Townsend
  
  08:05
  
  San Jose, CA
  Bus Stop
  
  0
  
  Economy
  
  £7
  
  A Bus from FlixBus goes from 5th/Townsend, San Francisco (USA) at 17/08/2026 07:10:00 to Bus Stop, San Jose, CA (USA) arriving at 17/08/2026 08:05:00. 50 Economy ticket for £7 per person are available. Travel duration is 0h 55m
- FlixBus
  
  14h 0m
  
  0
  
  08:15
  
  San Jose, CA
  Bus Stop
  
  22:15
  
  San Diego
  Seaport Village
  
  0
  
  Economy
  
  £34
  
  A Bus from FlixBus goes from Bus Stop, San Jose, CA (USA) at 17/08/2026 08:15:00 to Seaport Village, San Diego (USA) arriving at 17/08/2026 22:15:00. 50 Economy ticket for £34 per person are available. Travel duration is 14h 0m
Travel Time is 2h 15m shorter, and you will save £16

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	24h 25m	16:00	San Francisco	Salesforce Transit Center	16:25	San Diego	Old Town Transit Center	Economy	£44	A Bus from Greyhound US goes from Salesforce Transit Center, San Francisco (USA) at 17/08/2026 16:00:00 to Old Town Transit Center, San Diego (USA) arriving at 18/08/2026 16:25:00. 50 Economy ticket for £44 per person are available. Travel duration is 24h 25m
FlixBus	16h 20m	07:30	San Francisco	5th/Townsend	23:50	San Diego	Old Town Transit Center	Economy	£44	A Bus from FlixBus goes from 5th/Townsend, San Francisco (USA) at 17/08/2026 07:30:00 to Old Town Transit Center, San Diego (USA) arriving at 17/08/2026 23:50:00. 50 Economy ticket for £44 per person are available. Travel duration is 16h 20m
Greyhound US	17h 20m	06:30	San Francisco	Salesforce Transit Center	23:50	San Diego	Old Town Transit Center	Economy	£45	A Bus from Greyhound US goes from Salesforce Transit Center, San Francisco (USA) at 17/08/2026 06:30:00 to Old Town Transit Center, San Diego (USA) arriving at 17/08/2026 23:50:00. 50 Economy ticket for £45 per person are available. Travel duration is 17h 20m
FlixBus	14h 45m	07:30	San Francisco	5th/Townsend	22:15	San Diego	Seaport Village	Economy	£45	A Bus from FlixBus goes from 5th/Townsend, San Francisco (USA) at 17/08/2026 07:30:00 to Seaport Village, San Diego (USA) arriving at 17/08/2026 22:15:00. 50 Economy ticket for £45 per person are available. Travel duration is 14h 45m
Greyhound US	13h 15m	22:30	San Francisco	Salesforce Transit Center	11:45	San Diego	Old Town Transit Center	Economy	£56	A Bus from Greyhound US goes from Salesforce Transit Center, San Francisco (USA) at 17/08/2026 22:30:00 to Old Town Transit Center, San Diego (USA) arriving at 18/08/2026 11:45:00. 50 Economy ticket for £56 per person are available. Travel duration is 13h 15m

Best Price Offer: The price for the cheapest coach from San Francisco to San Diego is £40 on 10/08/2026. Flexible travellers save on ticket prices.

Frequency of bus connections between San Francisco and San Diego

See here how frequent the connections between San Francisco and San Diego are, during different times and days of the week.

Wednesday is the busiest day, with more than 21 daily coaches from San Francisco to San Diego. Saturday has instead the fewest connections, with only 4 daily coaches between San Francisco and San Diego.

The busiest time of the day is the Morning, with 26 coaches from San Francisco to San Diego, while Evening sees the fewest connections between San Francisco and San Diego, with 17 offers.

Facts about coaches from San Francisco to San Diego

Compare all providers like Greyhound US and FlixBus that travel 10 times every day by bus from San Francisco to San Diego in one click! Book your bus ticket from San Francisco to San Diego starting from £40!

Cheapest Bus	£40
Fastest Bus	13h 5m
Earliest Coach	06:30
Latest Coach	22:30
Daily Bus Connections	10 Ø
Distance	736.4 km
Coach Companies	Greyhound US and FlixBus

Cheapest coach connections from San Francisco to San Diego

Every day, 10 buses from 2 coach companies leave San Francisco for San Diego: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/08/2026 and for the following days.

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday

Monday 10/08

Tuesday 11/08

Wednesday 12/08

£65

Thursday 13/08

£47

Friday 14/08

£51

Saturday 15/08

£63

Sunday 16/08

£57

Monday 17/08

£44

Tuesday 18/08

Wednesday 19/08

£42

Thursday 20/08

£52

Friday 21/08

£60

Saturday 22/08

£64

Sunday 23/08

£55

Monday 24/08

Tuesday 25/08

£42

Wednesday 26/08

£47

Thursday 27/08

£51

Friday 28/08

£60

Saturday 29/08

£44

Sunday 30/08

£61

Monday 31/08

£50

Tuesday 01/09

£44

Wednesday 02/09

£54

Thursday 03/09

£48

Friday 04/09

Saturday 05/09

£55

Sunday 06/09

The cheapest time to travel from San Francisco to San Diego

See here on which day and which time of the day you can find the cheapest bus ticket from San Francisco to San Diego, for the next 30 days.

With a price starting from £42, Wednesday is the cheapest day for a coach from San Francisco to San Diego. Sunday instead is the most expensive day with prices starting from £55.

Morning is the cheapest day time for bus tickets from San Francisco to San Diego, with £44. Evening is the most expensive time of the day with prices starting from £51.

How to save money travelling from San Francisco to San Diego

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from San Francisco to San Diego in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from San Francisco to San Diego, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from San Francisco to San Diego are also emptier.

All bus stations and stops in San Francisco and San Diego

The map below shows you where to find all the bus stations in San Francisco and San Diego.

South Van Ness Ave & Market St

5th/Townsend

Townsend St 400

Union Square

Post St 470

Bus Station Transbay

Folsom Street 200

Beach St & Hyde St

Old Town Transit Center

Congress Street 2727

San Ysidro Transit Center

E San Ysidro Blvd 723

Seaport Village

W Harbor Dr 789

Santa Fe Depot

Kettner Blvd 1050

La Jolla Village

Hyatt Regency

Service and Comfort on the bus from San Francisco to San Diego

Want to know which seat classes are available on the coaches from San Francisco to San Diego? Or which bus companies serve the route San Francisco to San Diego? Below you will find answers to your questions.

FAQs about the San Francisco to San Diego bus

How much does a San Francisco - San Diego coach trip cost?

This depends on, among other things, the day and travel time. The cheapest ticket for the San Francisco - San Diego bus trip is available from £40 and takes 16h 20m. Compare offers and save money!

How much could I save by comparing buses from San Francisco to San Diego?

The connection San Francisco to San Diego is offered by 2 companies with ticket prices ranging from £40 to £142. Therefore, we suggest booking your ticket as soon as possible to ensure you will get the cheapest ticket price.

How many connections are available for the San Francisco - San Diego route on average every day?

Each day, the bus route from San Francisco to San Diego is offered by roughly 10 busses. By using our search, you can compare bus schedules and find your ideal trip.

How long does a bus to San Diego from San Francisco take?

The quickest coach from San Francisco to San Diego is provided by Greyhound US and takes 13h 5m. Coach tickets for this connection cost £62. However, keep in mind that the connection can take longer due to traffic.

What time is the first bus from San Francisco to San Diego?

The earliest bus to San Diego departs from San Francisco at 06:30. In this context, information about departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

What time is the last coach from San Francisco to San Diego?

The latest bus to San Diego departs from San Francisco at 22:30. Please note that departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

Which bus companies serve the San Francisco - San Diego route?

Passengers looking to travel from San Francisco to San Diego can travel with Greyhound US and FlixBus. Compare all available bus tickets with our search to book the trip that works best for you.

Is there a direct bus between San Francisco and San Diego?

You can check all the direct connections between San Francisco and San Diego by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.

What can I take with me on the bus to San Diego from San Francisco?

Depending on which provider you travel with, what you are allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the bus for the San Francisco San Diego bus route free of charge. Simply use our search to find a coach that is best suited to your needs for your planned travel date.

What equipment is available for the San Francisco San Diego bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make travelling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from San Francisco to San Diego on your planned travel date.

How does CheckMyBus find the best bus deals from San Francisco to San Diego?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 10 daily trips between San Francisco and San Diego. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from San Francisco to San Diego?

Prices and availability for 10 trips between San Francisco and San Diego change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route San Francisco to San Diego

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to San Francisco and to San Diego

Here’s an overview of the most popular bus routes to San Francisco and to San Diego. Simply click on the connection of your choice, and you will find all the details about your bus route!