Which bus from Messina to Palermo is the best?
Check the bus schedule for Messina to Palermo. Here is a selection of the cheapest coach trips for the next days from bus operators like Sais Autolinee or FlixBus. To see the full timetable for all coaches just use or search and compare.
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Sais Autolinee | 2h 45m | 04:40 | Messina | Piazza della Repubblica | 07:25 | Palermo | Oreto Orsi Bus Stop | Basic | £12 |
A Bus from Sais Autolinee goes from Piazza della Repubblica, Messina (Italy) at 05/12/2025 04:40:00 to Oreto Orsi Bus Stop, Palermo (Italy) arriving at 05/12/2025 07:25:00. 50 Basic ticket for £12 per person are available. Travel duration is 2h 45m
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| Sais Autolinee | 2h 40m | 06:30 | Messina | Piazza della Repubblica | 09:10 | Palermo | Oreto Orsi Bus Stop | Basic | £12 |
A Bus from Sais Autolinee goes from Piazza della Repubblica, Messina (Italy) at 05/12/2025 06:30:00 to Oreto Orsi Bus Stop, Palermo (Italy) arriving at 05/12/2025 09:10:00. 50 Basic ticket for £12 per person are available. Travel duration is 2h 40m
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| Sais Autolinee | 2h 45m | 09:00 | Messina | Piazza della Repubblica | 11:45 | Palermo | Oreto Orsi Bus Stop | Basic | £12 |
A Bus from Sais Autolinee goes from Piazza della Repubblica, Messina (Italy) at 05/12/2025 09:00:00 to Oreto Orsi Bus Stop, Palermo (Italy) arriving at 05/12/2025 11:45:00. 50 Basic ticket for £12 per person are available. Travel duration is 2h 45m
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| FlixBus | 4h 35m | 06:25 | Messina | Piazza della Repubblica | 11:00 | Palermo | Via Tommaso Fazello Bus Stop | Economy | £12 |
A Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 05/12/2025 06:25:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 05/12/2025 11:00:00. 50 Economy ticket for £12 per person are available. Travel duration is 4h 35m
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| FlixBus | 4h 55m | 12:00 | Messina | Piazza della Repubblica | 16:55 | Palermo | Via Tommaso Fazello Bus Stop | Economy | £13 |
A Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 05/12/2025 12:00:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 05/12/2025 16:55:00. 50 Economy ticket for £13 per person are available. Travel duration is 4h 55m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Sais Autolinee | 2h 50m | 09:00 | Messina | Piazza della Repubblica | 11:50 | Palermo | Via Tommaso Fazello Bus Stop | Basic | £12 |
A Bus from Sais Autolinee goes from Piazza della Repubblica, Messina (Italy) at 06/12/2025 09:00:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 06/12/2025 11:50:00. 50 Basic ticket for £12 per person are available. Travel duration is 2h 50m
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| Sais Autolinee | 2h 45m | 14:15 | Messina | Piazza della Repubblica | 17:00 | Palermo | Via Tommaso Fazello Bus Stop | Basic | £12 |
A Bus from Sais Autolinee goes from Piazza della Repubblica, Messina (Italy) at 06/12/2025 14:15:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 06/12/2025 17:00:00. 50 Basic ticket for £12 per person are available. Travel duration is 2h 45m
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| Sais Autolinee | 2h 45m | 18:00 | Messina | Piazza della Repubblica | 20:45 | Palermo | Via Tommaso Fazello Bus Stop | Basic | £12 |
A Bus from Sais Autolinee goes from Piazza della Repubblica, Messina (Italy) at 06/12/2025 18:00:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 06/12/2025 20:45:00. 50 Basic ticket for £12 per person are available. Travel duration is 2h 45m
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| FlixBus | 4h 0m | 10:25 | Messina | Piazza della Repubblica | 14:25 | Palermo | Via Tommaso Fazello Bus Stop | Economy | £13 |
A Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 06/12/2025 10:25:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 06/12/2025 14:25:00. 50 Economy ticket for £13 per person are available. Travel duration is 4h 0m
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| FlixBus | 4h 55m | 12:00 | Messina | Piazza della Repubblica | 16:55 | Palermo | Via Tommaso Fazello Bus Stop | Economy | £14 |
A Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 06/12/2025 12:00:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 06/12/2025 16:55:00. 50 Economy ticket for £14 per person are available. Travel duration is 4h 55m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Sais Autolinee | 2h 50m | 09:00 | Messina | Piazza della Repubblica | 11:50 | Palermo | Via Tommaso Fazello Bus Stop | Basic | £12 |
A Bus from Sais Autolinee goes from Piazza della Repubblica, Messina (Italy) at 07/12/2025 09:00:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 07/12/2025 11:50:00. 50 Basic ticket for £12 per person are available. Travel duration is 2h 50m
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| Sais Autolinee | 2h 45m | 12:00 | Messina | Piazza della Repubblica | 14:45 | Palermo | Via Tommaso Fazello Bus Stop | Basic | £12 |
A Bus from Sais Autolinee goes from Piazza della Repubblica, Messina (Italy) at 07/12/2025 12:00:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 07/12/2025 14:45:00. 50 Basic ticket for £12 per person are available. Travel duration is 2h 45m
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| Sais Autolinee | 2h 45m | 14:15 | Messina | Piazza della Repubblica | 17:00 | Palermo | Via Tommaso Fazello Bus Stop | Basic | £12 |
A Bus from Sais Autolinee goes from Piazza della Repubblica, Messina (Italy) at 07/12/2025 14:15:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 07/12/2025 17:00:00. 50 Basic ticket for £12 per person are available. Travel duration is 2h 45m
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| FlixBus | 4h 35m | 06:25 | Messina | Piazza della Repubblica | 11:00 | Palermo | Via Tommaso Fazello Bus Stop | Economy | £13 |
A Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 07/12/2025 06:25:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 07/12/2025 11:00:00. 50 Economy ticket for £13 per person are available. Travel duration is 4h 35m
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| FlixBus | 4h 0m | 10:25 | Messina | Piazza della Repubblica | 14:25 | Palermo | Via Tommaso Fazello Bus Stop | Economy | £14 |
A Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 07/12/2025 10:25:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 07/12/2025 14:25:00. 50 Economy ticket for £14 per person are available. Travel duration is 4h 0m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Sais Autolinee | 2h 45m | 09:00 | Messina | Piazza della Repubblica | 11:45 | Palermo | Oreto Orsi Bus Stop | Basic | £12 |
A Bus from Sais Autolinee goes from Piazza della Repubblica, Messina (Italy) at 08/12/2025 09:00:00 to Oreto Orsi Bus Stop, Palermo (Italy) arriving at 08/12/2025 11:45:00. 50 Basic ticket for £12 per person are available. Travel duration is 2h 45m
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| Sais Autolinee | 2h 40m | 12:00 | Messina | Piazza della Repubblica | 14:40 | Palermo | Oreto Orsi Bus Stop | Basic | £12 |
A Bus from Sais Autolinee goes from Piazza della Repubblica, Messina (Italy) at 08/12/2025 12:00:00 to Oreto Orsi Bus Stop, Palermo (Italy) arriving at 08/12/2025 14:40:00. 50 Basic ticket for £12 per person are available. Travel duration is 2h 40m
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| Sais Autolinee | 2h 40m | 14:15 | Messina | Piazza della Repubblica | 16:55 | Palermo | Oreto Orsi Bus Stop | Basic | £12 |
A Bus from Sais Autolinee goes from Piazza della Repubblica, Messina (Italy) at 08/12/2025 14:15:00 to Oreto Orsi Bus Stop, Palermo (Italy) arriving at 08/12/2025 16:55:00. 50 Basic ticket for £12 per person are available. Travel duration is 2h 40m
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| FlixBus | 4h 35m | 06:25 | Messina | Piazza della Repubblica | 11:00 | Palermo | Via Tommaso Fazello Bus Stop | Economy | £15 |
A Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 08/12/2025 06:25:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 08/12/2025 11:00:00. 50 Economy ticket for £15 per person are available. Travel duration is 4h 35m
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| FlixBus | 4h 0m | 10:25 | Messina | Piazza della Repubblica | 14:25 | Palermo | Via Tommaso Fazello Bus Stop | Economy | £17 |
A Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 08/12/2025 10:25:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 08/12/2025 14:25:00. 50 Economy ticket for £17 per person are available. Travel duration is 4h 0m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Sais Autolinee | 2h 45m | 04:40 | Messina | Piazza della Repubblica | 07:25 | Palermo | Oreto Orsi Bus Stop | Basic | £12 |
A Bus from Sais Autolinee goes from Piazza della Repubblica, Messina (Italy) at 09/12/2025 04:40:00 to Oreto Orsi Bus Stop, Palermo (Italy) arriving at 09/12/2025 07:25:00. 50 Basic ticket for £12 per person are available. Travel duration is 2h 45m
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| Sais Autolinee | 2h 40m | 06:30 | Messina | Piazza della Repubblica | 09:10 | Palermo | Oreto Orsi Bus Stop | Basic | £12 |
A Bus from Sais Autolinee goes from Piazza della Repubblica, Messina (Italy) at 09/12/2025 06:30:00 to Oreto Orsi Bus Stop, Palermo (Italy) arriving at 09/12/2025 09:10:00. 50 Basic ticket for £12 per person are available. Travel duration is 2h 40m
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| Sais Autolinee | 2h 45m | 09:00 | Messina | Piazza della Repubblica | 11:45 | Palermo | Oreto Orsi Bus Stop | Basic | £12 |
A Bus from Sais Autolinee goes from Piazza della Repubblica, Messina (Italy) at 09/12/2025 09:00:00 to Oreto Orsi Bus Stop, Palermo (Italy) arriving at 09/12/2025 11:45:00. 50 Basic ticket for £12 per person are available. Travel duration is 2h 45m
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| FlixBus | 4h 35m | 06:25 | Messina | Piazza della Repubblica | 11:00 | Palermo | Via Tommaso Fazello Bus Stop | Economy | £14 |
A Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 09/12/2025 06:25:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 09/12/2025 11:00:00. 50 Economy ticket for £14 per person are available. Travel duration is 4h 35m
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| FlixBus | 4h 0m | 10:25 | Messina | Piazza della Repubblica | 14:25 | Palermo | Via Tommaso Fazello Bus Stop | Economy | £14 |
A Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 09/12/2025 10:25:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 09/12/2025 14:25:00. 50 Economy ticket for £14 per person are available. Travel duration is 4h 0m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Sais Autolinee | 2h 45m | 04:40 | Messina | Piazza della Repubblica | 07:25 | Palermo | Oreto Orsi Bus Stop | Basic | £12 |
A Bus from Sais Autolinee goes from Piazza della Repubblica, Messina (Italy) at 10/12/2025 04:40:00 to Oreto Orsi Bus Stop, Palermo (Italy) arriving at 10/12/2025 07:25:00. 50 Basic ticket for £12 per person are available. Travel duration is 2h 45m
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| Sais Autolinee | 2h 40m | 06:30 | Messina | Piazza della Repubblica | 09:10 | Palermo | Oreto Orsi Bus Stop | Basic | £12 |
A Bus from Sais Autolinee goes from Piazza della Repubblica, Messina (Italy) at 10/12/2025 06:30:00 to Oreto Orsi Bus Stop, Palermo (Italy) arriving at 10/12/2025 09:10:00. 50 Basic ticket for £12 per person are available. Travel duration is 2h 40m
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| Sais Autolinee | 2h 45m | 09:00 | Messina | Piazza della Repubblica | 11:45 | Palermo | Oreto Orsi Bus Stop | Basic | £12 |
A Bus from Sais Autolinee goes from Piazza della Repubblica, Messina (Italy) at 10/12/2025 09:00:00 to Oreto Orsi Bus Stop, Palermo (Italy) arriving at 10/12/2025 11:45:00. 50 Basic ticket for £12 per person are available. Travel duration is 2h 45m
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| FlixBus | 4h 0m | 10:25 | Messina | Piazza della Repubblica | 14:25 | Palermo | Via Tommaso Fazello Bus Stop | Economy | £12 |
A Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 10/12/2025 10:25:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 10/12/2025 14:25:00. 50 Economy ticket for £12 per person are available. Travel duration is 4h 0m
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| FlixBus | 4h 35m | 06:25 | Messina | Piazza della Repubblica | 11:00 | Palermo | Via Tommaso Fazello Bus Stop | Economy | £13 |
A Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 10/12/2025 06:25:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 10/12/2025 11:00:00. 50 Economy ticket for £13 per person are available. Travel duration is 4h 35m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Sais Autolinee | 2h 45m | 04:40 | Messina | Piazza della Repubblica | 07:25 | Palermo | Oreto Orsi Bus Stop | Basic | £12 |
A Bus from Sais Autolinee goes from Piazza della Repubblica, Messina (Italy) at 11/12/2025 04:40:00 to Oreto Orsi Bus Stop, Palermo (Italy) arriving at 11/12/2025 07:25:00. 50 Basic ticket for £12 per person are available. Travel duration is 2h 45m
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| Sais Autolinee | 2h 40m | 06:30 | Messina | Piazza della Repubblica | 09:10 | Palermo | Oreto Orsi Bus Stop | Basic | £12 |
A Bus from Sais Autolinee goes from Piazza della Repubblica, Messina (Italy) at 11/12/2025 06:30:00 to Oreto Orsi Bus Stop, Palermo (Italy) arriving at 11/12/2025 09:10:00. 50 Basic ticket for £12 per person are available. Travel duration is 2h 40m
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| Sais Autolinee | 2h 45m | 09:00 | Messina | Piazza della Repubblica | 11:45 | Palermo | Oreto Orsi Bus Stop | Basic | £12 |
A Bus from Sais Autolinee goes from Piazza della Repubblica, Messina (Italy) at 11/12/2025 09:00:00 to Oreto Orsi Bus Stop, Palermo (Italy) arriving at 11/12/2025 11:45:00. 50 Basic ticket for £12 per person are available. Travel duration is 2h 45m
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| FlixBus | 4h 35m | 06:25 | Messina | Piazza della Repubblica | 11:00 | Palermo | Via Tommaso Fazello Bus Stop | Economy | £12 |
A Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 11/12/2025 06:25:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 11/12/2025 11:00:00. 50 Economy ticket for £12 per person are available. Travel duration is 4h 35m
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| FlixBus | 4h 55m | 12:00 | Messina | Piazza della Repubblica | 16:55 | Palermo | Via Tommaso Fazello Bus Stop | Economy | £12 |
A Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 11/12/2025 12:00:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 11/12/2025 16:55:00. 50 Economy ticket for £12 per person are available. Travel duration is 4h 55m
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Best Price Offer: The price for the cheapest coach from Messina to Palermo is £11 on 17/12/2025. Flexible travellers save on ticket prices.
What is the best day and time to travel by bus between Messina and Palermo?
All facts for Messina to Palermo bus at a glance
Compare all coach operators like Sais Autolinee and FlixBus that travel daily 66 times by bus from Messina to Palermo in one click. Book your Messina to Palermo bus ticket starting from £11!
| Cheapest Bus | £11 |
| Fastest Bus | 2h 35m |
| Earliest Coach | 04:40 |
| Latest Coach | 18:05 |
| Daily Bus Connections | 66 Ø |
| Distance | 191.9 km |
| Coach Companies | Sais Autolinee and FlixBus |
What are the cheapest coach tickets from Messina to Palermo?
Every day, 66 buses from 2 coach companies leave Messina for Palermo. Check the table below to find the cheapest prices for coach tickets for this route, starting from 05/12/2025 and for the following days. Make sure get the cheapest bus ticket!
The cheapest time to travel from Messina to Palermo
How to save money travelling from Messina to Palermo
Book the ticket from Messina to Palermo in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the coach from Messina to Palermo, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Messina to Palermo are also emptier.Check for bus deals and promotions for all bus companies in this route. On CheckMyBus we show special offers directly in the coach trip on our search. Sign-up and check or deals sections and get notifications on our latest travel hacks.
All bus stations and stops in Messina and Palermo
Here is a map with all coach stations in Messina and Palermo. Compare which stop is closest to your destination to save time to find the fastest buses and connections.
Compare the bus with other modes of transport
All you need to know when you travel by bus from Messina to Palermo
FAQs for Messina to Palermo bus
How much does a Messina Palermo coach trip cost?
How much could I save by comparing buses from Messina to Palermo?
How many connections are available for the Messina Palermo route on average every day?
How long does a bus to Palermo from Messina take?
What time is the first bus from Messina to Palermo?
What time is the last coach from Messina to Palermo?
Which bus companies serve the Messina Palermo route?
Is there a direct bus between Messina and Palermo?
What can I take with me on the bus to Palermo from Messina?
What equipment is available for the Messina Palermo bus route?
Available seat classes which are offered on the bus route Messina to Palermo
Name referring to the typical seat you will find with companies that don’t distinguish between different classes.
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
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