Which bus from Florence to Palermo is the best?
Check the bus schedule for Florence to Palermo. Here is a selection of the cheapest coach trips for the next days from bus operators like FlixBus or Autoservizi Salemi. To see the full timetable for all coaches just use or search and compare.
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 20h 30m | 17:55 | Florence | Villa Costanza Bus Station | 14:25 | Palermo | Via Tommaso Fazello Bus Stop | Economy | £115 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 16/12/2025 17:55:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 17/12/2025 14:25:00. 50 Economy ticket for £115 per person are available. Travel duration is 20h 30m
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| FlixBus | 17h 5m | 17:55 | Florence | Villa Costanza Bus Station | 11:00 | Palermo | Via Tommaso Fazello Bus Stop | Economy | £135 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 16/12/2025 17:55:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 17/12/2025 11:00:00. 50 Economy ticket for £135 per person are available. Travel duration is 17h 5m
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| FlixBus | 16h 25m | 22:00 | Florence | Villa Costanza Bus Station | 14:25 | Palermo | Via Tommaso Fazello Bus Stop | Economy | £135 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 16/12/2025 22:00:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 17/12/2025 14:25:00. 50 Economy ticket for £135 per person are available. Travel duration is 16h 25m
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Bookaway23h 5m017:50FlorenceVilla Costanza Bus Station21:40RomeTiburtina Coach Station0BasicA Bus from Bookaway goes from Villa Costanza Bus Station, Florence (Italy) at 17/12/2025 17:50:00 to Tiburtina Coach Station, Rome (Italy) arriving at 17/12/2025 21:40:00. 50 Basic ticket for £9 per person are available. Travel duration is 3h 50m
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FlixBus17h 25m023:30RomeTiburtina Bus Station16:55PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 17/12/2025 23:30:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 18/12/2025 16:55:00. 50 Economy ticket for £76 per person are available. Travel duration is 17h 25m
Waiting Time 1h 50m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 17h 5m | 17:55 | Florence | Villa Costanza Bus Station | 11:00 | Palermo | Via Tommaso Fazello Bus Stop | Economy | £97 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 18/12/2025 17:55:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 19/12/2025 11:00:00. 50 Economy ticket for £97 per person are available. Travel duration is 17h 5m
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Distribusion17h 30m014:30FlorenceVilla Costanza Bus Station17:45RomeTiburtina Bus Station0Premium EconomyA Bus from Distribusion goes from Villa Costanza Bus Station, Florence (Italy) at 19/12/2025 14:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 19/12/2025 17:45:00. 50 Premium Economy ticket for £8 per person are available. Travel duration is 3h 15m
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INFOBUS13h 15m018:45RomeTiburtina Bus Station08:00PalermoPiazza Cairoli Bus Station0EconomyA Bus from INFOBUS goes from Tiburtina Bus Station, Rome (Italy) at 19/12/2025 18:45:00 to Piazza Cairoli Bus Station, Palermo (Italy) arriving at 20/12/2025 08:00:00. 50 Economy ticket for £40 per person are available. Travel duration is 13h 15m
Waiting Time 1h 0m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Autoservizi Salemi | 16h 0m | 15:45 | Florence | Villa Costanza Bus Station | 07:45 | Palermo | Via Tommaso Fazello Bus Stop | Basic | £96 |
A Bus from Autoservizi Salemi goes from Villa Costanza Bus Station, Florence (Italy) at 19/12/2025 15:45:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 20/12/2025 07:45:00. 50 Basic ticket for £96 per person are available. Travel duration is 16h 0m
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| FlixBus | 20h 15m | 18:10 | Florence | Villa Costanza Bus Station | 14:25 | Palermo | Via Tommaso Fazello Bus Stop | Economy | £113 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 19/12/2025 18:10:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 20/12/2025 14:25:00. 50 Economy ticket for £113 per person are available. Travel duration is 20h 15m
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| FlixBus | 17h 20m | 17:55 | Florence | Villa Costanza Bus Station | 11:15 | Palermo | Via Tommaso Fazello Bus Stop | Economy | £114 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 19/12/2025 17:55:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 20/12/2025 11:15:00. 50 Economy ticket for £114 per person are available. Travel duration is 17h 20m
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| FlixBus | 17h 5m | 17:55 | Florence | Villa Costanza Bus Station | 11:00 | Palermo | Via Tommaso Fazello Bus Stop | Economy | £120 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 19/12/2025 17:55:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 20/12/2025 11:00:00. 50 Economy ticket for £120 per person are available. Travel duration is 17h 5m
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| Autoservizi Salemi | 16h 0m | 23:45 | Florence | Villa Costanza Bus Station | 15:45 | Palermo | Via Tommaso Fazello Bus Stop | Basic | £133 |
A Bus from Autoservizi Salemi goes from Villa Costanza Bus Station, Florence (Italy) at 19/12/2025 23:45:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 20/12/2025 15:45:00. 50 Basic ticket for £133 per person are available. Travel duration is 16h 0m
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Distribusion17h 30m014:30FlorenceVilla Costanza Bus Station17:45RomeTiburtina Bus Station0Premium EconomyA Bus from Distribusion goes from Villa Costanza Bus Station, Florence (Italy) at 19/12/2025 14:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 19/12/2025 17:45:00. 50 Premium Economy ticket for £8 per person are available. Travel duration is 3h 15m
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INFOBUS13h 15m018:45RomeTiburtina Bus Station08:00PalermoPiazza Cairoli Bus Station0EconomyA Bus from INFOBUS goes from Tiburtina Bus Station, Rome (Italy) at 19/12/2025 18:45:00 to Piazza Cairoli Bus Station, Palermo (Italy) arriving at 20/12/2025 08:00:00. 50 Economy ticket for £40 per person are available. Travel duration is 13h 15m
Waiting Time 1h 0m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 17h 5m | 17:55 | Florence | Villa Costanza Bus Station | 11:00 | Palermo | Via Tommaso Fazello Bus Stop | Economy | £131 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 20/12/2025 17:55:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 21/12/2025 11:00:00. 50 Economy ticket for £131 per person are available. Travel duration is 17h 5m
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| FlixBus | 16h 25m | 22:00 | Florence | Villa Costanza Bus Station | 14:25 | Palermo | Via Tommaso Fazello Bus Stop | Economy | £131 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 20/12/2025 22:00:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 21/12/2025 14:25:00. 50 Economy ticket for £131 per person are available. Travel duration is 16h 25m
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| FlixBus | 20h 30m | 17:55 | Florence | Villa Costanza Bus Station | 14:25 | Palermo | Via Tommaso Fazello Bus Stop | Economy | £138 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 20/12/2025 17:55:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 21/12/2025 14:25:00. 50 Economy ticket for £138 per person are available. Travel duration is 20h 30m
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Distribusion17h 30m014:30FlorenceVilla Costanza Bus Station17:45RomeTiburtina Bus Station0Premium EconomyA Bus from Distribusion goes from Villa Costanza Bus Station, Florence (Italy) at 19/12/2025 14:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 19/12/2025 17:45:00. 50 Premium Economy ticket for £8 per person are available. Travel duration is 3h 15m
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INFOBUS13h 15m018:45RomeTiburtina Bus Station08:00PalermoPiazza Cairoli Bus Station0EconomyA Bus from INFOBUS goes from Tiburtina Bus Station, Rome (Italy) at 19/12/2025 18:45:00 to Piazza Cairoli Bus Station, Palermo (Italy) arriving at 20/12/2025 08:00:00. 50 Economy ticket for £40 per person are available. Travel duration is 13h 15m
Waiting Time 1h 0m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 17h 5m | 17:55 | Florence | Villa Costanza Bus Station | 11:00 | Palermo | Via Tommaso Fazello Bus Stop | Economy | £123 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 21/12/2025 17:55:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 22/12/2025 11:00:00. 50 Economy ticket for £123 per person are available. Travel duration is 17h 5m
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| FlixBus | 16h 25m | 22:00 | Florence | Villa Costanza Bus Station | 14:25 | Palermo | Via Tommaso Fazello Bus Stop | Economy | £123 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 21/12/2025 22:00:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 22/12/2025 14:25:00. 50 Economy ticket for £123 per person are available. Travel duration is 16h 25m
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| FlixBus | 20h 30m | 17:55 | Florence | Villa Costanza Bus Station | 14:25 | Palermo | Via Tommaso Fazello Bus Stop | Economy | £127 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 21/12/2025 17:55:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 22/12/2025 14:25:00. 50 Economy ticket for £127 per person are available. Travel duration is 20h 30m
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Distribusion17h 30m014:30FlorenceVilla Costanza Bus Station17:45RomeTiburtina Bus Station0Premium EconomyA Bus from Distribusion goes from Villa Costanza Bus Station, Florence (Italy) at 19/12/2025 14:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 19/12/2025 17:45:00. 50 Premium Economy ticket for £8 per person are available. Travel duration is 3h 15m
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INFOBUS13h 15m018:45RomeTiburtina Bus Station08:00PalermoPiazza Cairoli Bus Station0EconomyA Bus from INFOBUS goes from Tiburtina Bus Station, Rome (Italy) at 19/12/2025 18:45:00 to Piazza Cairoli Bus Station, Palermo (Italy) arriving at 20/12/2025 08:00:00. 50 Economy ticket for £40 per person are available. Travel duration is 13h 15m
Waiting Time 1h 0m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 20h 30m | 17:55 | Florence | Villa Costanza Bus Station | 14:25 | Palermo | Via Tommaso Fazello Bus Stop | Economy | £122 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 22/12/2025 17:55:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 23/12/2025 14:25:00. 50 Economy ticket for £122 per person are available. Travel duration is 20h 30m
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| FlixBus | 17h 5m | 17:55 | Florence | Villa Costanza Bus Station | 11:00 | Palermo | Via Tommaso Fazello Bus Stop | Economy | £123 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 22/12/2025 17:55:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 23/12/2025 11:00:00. 50 Economy ticket for £123 per person are available. Travel duration is 17h 5m
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| FlixBus | 16h 25m | 22:00 | Florence | Villa Costanza Bus Station | 14:25 | Palermo | Via Tommaso Fazello Bus Stop | Economy | £123 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 22/12/2025 22:00:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 23/12/2025 14:25:00. 50 Economy ticket for £123 per person are available. Travel duration is 16h 25m
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Distribusion17h 30m014:30FlorenceVilla Costanza Bus Station17:45RomeTiburtina Bus Station0Premium EconomyA Bus from Distribusion goes from Villa Costanza Bus Station, Florence (Italy) at 19/12/2025 14:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 19/12/2025 17:45:00. 50 Premium Economy ticket for £8 per person are available. Travel duration is 3h 15m
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INFOBUS13h 15m018:45RomeTiburtina Bus Station08:00PalermoPiazza Cairoli Bus Station0EconomyA Bus from INFOBUS goes from Tiburtina Bus Station, Rome (Italy) at 19/12/2025 18:45:00 to Piazza Cairoli Bus Station, Palermo (Italy) arriving at 20/12/2025 08:00:00. 50 Economy ticket for £40 per person are available. Travel duration is 13h 15m
Waiting Time 1h 0m -
Best Price Offer: The price for the cheapest coach from Florence to Palermo is £26 on 09/01/2026. Flexible travellers save on ticket prices.
What is the best day and time to travel by bus between Florence and Palermo?
All facts for Florence to Palermo bus at a glance
Compare all coach operators like FlixBus and Autoservizi Salemi that travel daily 4 times by bus from Florence to Palermo in one click. Book your Florence to Palermo bus ticket starting from £26!
| Cheapest Bus | £26 |
| Fastest Bus | 16h 0m |
| Earliest Coach | 17:55 |
| Latest Coach | 22:00 |
| Daily Bus Connections | 4 Ø |
| Distance | 653.4 km |
| Coach Companies | FlixBus and Autoservizi Salemi |
What are the cheapest coach tickets from Florence to Palermo?
Every day, 4 buses from 2 coach companies leave Florence for Palermo. Check the table below to find the cheapest prices for coach tickets for this route, starting from 16/12/2025 and for the following days. Make sure get the cheapest bus ticket!
The cheapest time to travel from Florence to Palermo
How to save money travelling from Florence to Palermo
Book the ticket from Florence to Palermo in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the coach from Florence to Palermo, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Florence to Palermo are also emptier.Check for bus deals and promotions for all bus companies in this route. On CheckMyBus we show special offers directly in the coach trip on our search. Sign-up and check or deals sections and get notifications on our latest travel hacks.
All bus stations and stops in Florence and Palermo
Here is a map with all coach stations in Florence and Palermo. Compare which stop is closest to your destination to save time to find the fastest buses and connections.
Compare the bus with other modes of transport
All you need to know when you travel by bus from Florence to Palermo
FAQs for Florence to Palermo bus
How much does a Florence Palermo coach trip cost?
How much could I save by comparing buses from Florence to Palermo?
How many connections are available for the Florence Palermo route on average every day?
How long does a bus to Palermo from Florence take?
What time is the first bus from Florence to Palermo?
What time is the last coach from Florence to Palermo?
Which bus companies serve the Florence Palermo route?
Is there a direct bus between Florence and Palermo?
What can I take with me on the bus to Palermo from Florence?
What equipment is available for the Florence Palermo bus route?
How does CheckMyBus find the best coach deals from Florence to Palermo?
How does CheckMyBus technology work for trips from Florence to Palermo?
Available seat classes which are offered on the bus route Florence to Palermo
Name referring to the typical seat you will find with companies that don’t distinguish between different classes.
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
More bus routes to Florence and to Palermo
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