Which bus from Florence to Palermo is the best?
Check the bus schedule for Florence to Palermo. Here is a selection of the cheapest coach trips for the next days from bus operators like FlixBus. To see the full timetable for all coaches just use or search and compare.
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 17h 15m | 22:00 | Florence | Villa Costanza Bus Station | 15:15 | Palermo | Via Tommaso Fazello Bus Stop | Economy | £50 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 16/09/2026 22:00:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 17/09/2026 15:15:00. 50 Economy ticket for £50 per person are available. Travel duration is 17h 15m
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| FlixBus | 17h 0m | 18:00 | Florence | Villa Costanza Bus Station | 11:00 | Palermo | Via Tommaso Fazello Bus Stop | Economy | £51 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 16/09/2026 18:00:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 17/09/2026 11:00:00. 50 Economy ticket for £51 per person are available. Travel duration is 17h 0m
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Itabus19h 30m012:20FlorenceVilla Costanza Bus Station15:35RomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 18/09/2026 12:20:00 to Tiburtina Bus Station, Rome (Italy) arriving at 18/09/2026 15:35:00. 50 Premium Economy ticket for £5 per person are available. Travel duration is 3h 15m
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Itabus13h 35m018:15RomeTiburtina Bus Station07:50PalermoPiazza Cairoli Bus Station0EconomyA Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 18/09/2026 18:15:00 to Piazza Cairoli Bus Station, Palermo (Italy) arriving at 19/09/2026 07:50:00. 50 Economy ticket for £24 per person are available. Travel duration is 13h 35m
Waiting Time 2h 40m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 17h 0m | 18:00 | Florence | Villa Costanza Bus Station | 11:00 | Palermo | Via Tommaso Fazello Bus Stop | Economy | £47 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 17/09/2026 18:00:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 18/09/2026 11:00:00. 50 Economy ticket for £47 per person are available. Travel duration is 17h 0m
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| FlixBus | 17h 15m | 22:00 | Florence | Villa Costanza Bus Station | 15:15 | Palermo | Via Tommaso Fazello Bus Stop | Economy | £49 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 17/09/2026 22:00:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 18/09/2026 15:15:00. 50 Economy ticket for £49 per person are available. Travel duration is 17h 15m
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FlixBus17h 10m014:40FlorenceVilla Costanza Bus Station18:05RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 19/09/2026 14:40:00 to Anagnina Bus Station, Rome (Italy) arriving at 19/09/2026 18:05:00. 50 Economy ticket for £6 per person are available. Travel duration is 3h 25m
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Itabus13h 35m018:15RomeTiburtina Bus Station07:50PalermoVia Fazello0Premium EconomyA Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 19/09/2026 18:15:00 to Via Fazello, Palermo (Italy) arriving at 20/09/2026 07:50:00. 50 Premium Economy ticket for £20 per person are available. Travel duration is 13h 35m
Waiting Time 0h 10m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 17h 0m | 18:00 | Florence | Villa Costanza Bus Station | 11:00 | Palermo | Via Tommaso Fazello Bus Stop | Economy | £51 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 18/09/2026 18:00:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 19/09/2026 11:00:00. 50 Economy ticket for £51 per person are available. Travel duration is 17h 0m
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| FlixBus | 17h 15m | 22:00 | Florence | Villa Costanza Bus Station | 15:15 | Palermo | Via Tommaso Fazello Bus Stop | Economy | £60 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 18/09/2026 22:00:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 19/09/2026 15:15:00. 50 Economy ticket for £60 per person are available. Travel duration is 17h 15m
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Itabus23h 25m008:25FlorenceVilla Costanza Bus Station12:15RomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 20/09/2026 08:25:00 to Tiburtina Bus Station, Rome (Italy) arriving at 20/09/2026 12:15:00. 50 Premium Economy ticket for £4 per person are available. Travel duration is 3h 50m
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Itabus13h 35m018:15RomeTiburtina Bus Station07:50PalermoVia Fazello0Premium EconomyA Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 20/09/2026 18:15:00 to Via Fazello, Palermo (Italy) arriving at 21/09/2026 07:50:00. 50 Premium Economy ticket for £20 per person are available. Travel duration is 13h 35m
Waiting Time 6h 0m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 17h 15m | 22:00 | Florence | Villa Costanza Bus Station | 15:15 | Palermo | Via Tommaso Fazello Bus Stop | Economy | £51 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 19/09/2026 22:00:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 20/09/2026 15:15:00. 50 Economy ticket for £51 per person are available. Travel duration is 17h 15m
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| FlixBus | 17h 0m | 18:00 | Florence | Villa Costanza Bus Station | 11:00 | Palermo | Via Tommaso Fazello Bus Stop | Economy | £55 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 19/09/2026 18:00:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 20/09/2026 11:00:00. 50 Economy ticket for £55 per person are available. Travel duration is 17h 0m
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Itabus23h 25m008:25FlorenceVilla Costanza Bus Station12:15RomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 20/09/2026 08:25:00 to Tiburtina Bus Station, Rome (Italy) arriving at 20/09/2026 12:15:00. 50 Premium Economy ticket for £4 per person are available. Travel duration is 3h 50m
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Itabus13h 35m018:15RomeTiburtina Bus Station07:50PalermoVia Fazello0Premium EconomyA Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 20/09/2026 18:15:00 to Via Fazello, Palermo (Italy) arriving at 21/09/2026 07:50:00. 50 Premium Economy ticket for £20 per person are available. Travel duration is 13h 35m
Waiting Time 6h 0m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 17h 0m | 18:00 | Florence | Villa Costanza Bus Station | 11:00 | Palermo | Via Tommaso Fazello Bus Stop | Economy | £49 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 20/09/2026 18:00:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 21/09/2026 11:00:00. 50 Economy ticket for £49 per person are available. Travel duration is 17h 0m
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| FlixBus | 17h 15m | 22:00 | Florence | Villa Costanza Bus Station | 15:15 | Palermo | Via Tommaso Fazello Bus Stop | Economy | £53 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 20/09/2026 22:00:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 21/09/2026 15:15:00. 50 Economy ticket for £53 per person are available. Travel duration is 17h 15m
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Itabus23h 25m008:25FlorenceVilla Costanza Bus Station12:15RomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 20/09/2026 08:25:00 to Tiburtina Bus Station, Rome (Italy) arriving at 20/09/2026 12:15:00. 50 Premium Economy ticket for £4 per person are available. Travel duration is 3h 50m
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Itabus13h 35m018:15RomeTiburtina Bus Station07:50PalermoVia Fazello0Premium EconomyA Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 20/09/2026 18:15:00 to Via Fazello, Palermo (Italy) arriving at 21/09/2026 07:50:00. 50 Premium Economy ticket for £20 per person are available. Travel duration is 13h 35m
Waiting Time 6h 0m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 17h 0m | 18:00 | Florence | Villa Costanza Bus Station | 11:00 | Palermo | Via Tommaso Fazello Bus Stop | Economy | £45 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 21/09/2026 18:00:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 22/09/2026 11:00:00. 50 Economy ticket for £45 per person are available. Travel duration is 17h 0m
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| FlixBus | 17h 15m | 22:00 | Florence | Villa Costanza Bus Station | 15:15 | Palermo | Via Tommaso Fazello Bus Stop | Economy | £45 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 21/09/2026 22:00:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 22/09/2026 15:15:00. 50 Economy ticket for £45 per person are available. Travel duration is 17h 15m
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Itabus23h 50m015:25FlorenceVilla Costanza Bus Station19:15RomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 22/09/2026 15:25:00 to Tiburtina Bus Station, Rome (Italy) arriving at 22/09/2026 19:15:00. 50 Premium Economy ticket for £5 per person are available. Travel duration is 3h 50m
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FlixBus13h 55m001:20RomeTiburtina Bus Station15:15PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 23/09/2026 01:20:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 23/09/2026 15:15:00. 50 Economy ticket for £15 per person are available. Travel duration is 13h 55m
Waiting Time 6h 5m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 17h 0m | 18:00 | Florence | Villa Costanza Bus Station | 11:00 | Palermo | Via Tommaso Fazello Bus Stop | Economy | £43 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 22/09/2026 18:00:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 23/09/2026 11:00:00. 50 Economy ticket for £43 per person are available. Travel duration is 17h 0m
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| FlixBus | 17h 15m | 22:00 | Florence | Villa Costanza Bus Station | 15:15 | Palermo | Via Tommaso Fazello Bus Stop | Economy | £43 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 22/09/2026 22:00:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 23/09/2026 15:15:00. 50 Economy ticket for £43 per person are available. Travel duration is 17h 15m
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Itabus23h 50m015:25FlorenceVilla Costanza Bus Station19:15RomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 22/09/2026 15:25:00 to Tiburtina Bus Station, Rome (Italy) arriving at 22/09/2026 19:15:00. 50 Premium Economy ticket for £5 per person are available. Travel duration is 3h 50m
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FlixBus13h 55m001:20RomeTiburtina Bus Station15:15PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 23/09/2026 01:20:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 23/09/2026 15:15:00. 50 Economy ticket for £15 per person are available. Travel duration is 13h 55m
Waiting Time 6h 5m -
Best Price Offer: The price for the cheapest coach from Florence to Palermo is £39 on 08/10/2026. Flexible travellers save on ticket prices.
All facts for Florence to Palermo bus at a glance
Compare all coach operators like FlixBus that travel daily 3 times by bus from Florence to Palermo in one click. Book your Florence to Palermo bus ticket starting from £39!
| Cheapest Bus | £39 |
| Fastest Bus | 17h 0m |
| Earliest Coach | 18:00 |
| Latest Coach | 22:00 |
| Daily Bus Connections | 3 Ø |
| Distance | 653.4 km |
| Coach Companies | FlixBus |
What are the cheapest coach tickets from Florence to Palermo?
Every day, 3 buses from 1 coach companies leave Florence for Palermo. Check the table below to find the cheapest prices for coach tickets for this route, starting from 16/09/2026 and for the following days. Make sure get the cheapest bus ticket!
How to save money travelling from Florence to Palermo
Book the ticket from Florence to Palermo in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the coach from Florence to Palermo, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Florence to Palermo are also emptier.Check for bus deals and promotions for all bus companies in this route. On CheckMyBus we show special offers directly in the coach trip on our search. Sign-up and check or deals sections and get notifications on our latest travel hacks.
All bus stations and stops in Florence and Palermo
Here is a map with all coach stations in Florence and Palermo. Compare which stop is closest to your destination to save time to find the fastest buses and connections.
All you need to know when you travel by bus from Florence to Palermo
FAQs for Florence to Palermo bus
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Available seat classes which are offered on the bus route Florence to Palermo
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
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