Which bus from Milan to Palermo is the best?
Check the bus schedule for Milan to Palermo. Here is a selection of the cheapest coach trips for the next days from bus operators like FlixBus, Autoservizi Salemi or MarinoBus. To see the full timetable for all coaches just use or search and compare.
Cheapest bus trips today
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FlixBus22h 5m012:55MilanLampugnano Bus Station11:00PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 07/07/2025 12:55:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 08/07/2025 11:00:00. 50 Economy ticket for £108 per person are available. Travel duration is 22h 5m
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FlixBus25h 25m015:30MilanLampugnano Bus Station16:55PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 07/07/2025 15:30:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 08/07/2025 16:55:00. 50 Economy ticket for £109 per person are available. Travel duration is 25h 25m
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FlixBus26h 10m014:45MilanSan Donato Bus Station16:55PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 07/07/2025 14:45:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 08/07/2025 16:55:00. 50 Economy ticket for £129 per person are available. Travel duration is 26h 10m
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FlixBus23h 50m010:30MilanLampugnano Bus Station10:20PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 07/07/2025 10:30:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 08/07/2025 10:20:00. 50 Economy ticket for £130 per person are available. Travel duration is 23h 50m
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FlixBus25h 20m009:40MilanSan Donato Bus Station11:00PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 07/07/2025 09:40:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 08/07/2025 11:00:00. 50 Economy ticket for £131 per person are available. Travel duration is 25h 20m
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FlixBus22h 35m012:25MilanLampugnano Bus Station18:15SienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 08/07/2025 12:25:00 to Train Station, Siena (Italy) arriving at 08/07/2025 18:15:00. 50 Economy ticket for £19 per person are available. Travel duration is 5h 50m
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FlixBus16h 5m018:55SienaTrain Station11:00PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from Train Station, Siena (Italy) at 08/07/2025 18:55:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 09/07/2025 11:00:00. 50 Economy ticket for £49 per person are available. Travel duration is 16h 5m
Waiting Time 0h 40m -
Cheapest bus trips tomorrow
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Autoservizi Salemi21h 45m010:00MilanLampugnano Bus Station07:45PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from Autoservizi Salemi goes from Lampugnano Bus Station, Milan (Italy) at 08/07/2025 10:00:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 09/07/2025 07:45:00. 50 Economy ticket for £76 per person are available. Travel duration is 21h 45m
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Autoservizi Salemi21h 0m010:45MilanSan Donato Bus Station07:45PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from Autoservizi Salemi goes from San Donato Bus Station, Milan (Italy) at 08/07/2025 10:45:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 09/07/2025 07:45:00. 50 Economy ticket for £76 per person are available. Travel duration is 21h 0m
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FlixBus22h 5m012:55MilanLampugnano Bus Station11:00PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 08/07/2025 12:55:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 09/07/2025 11:00:00. 50 Economy ticket for £85 per person are available. Travel duration is 22h 5m
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MarinoBus24h 15m008:40MilanLampugnano Bus Station08:55PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from MarinoBus goes from Lampugnano Bus Station, Milan (Italy) at 08/07/2025 08:40:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 09/07/2025 08:55:00. 50 Economy ticket for £93 per person are available. Travel duration is 24h 15m
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MarinoBus23h 30m009:25MilanSan Donato Bus Station08:55PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from MarinoBus goes from San Donato Bus Station, Milan (Italy) at 08/07/2025 09:25:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 09/07/2025 08:55:00. 50 Economy ticket for £93 per person are available. Travel duration is 23h 30m
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FlixBusSave more than 30%26h 45mMilan10 km11:40CormanoCusano Milanino Bus Stop14:25PalermoVia Tommaso Fazello Bus Stop0 kmEconomyA Bus from FlixBus goes from Cusano Milanino Bus Stop, Cormano (Italy) at 08/07/2025 11:40:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 09/07/2025 14:25:00. 50 Economy ticket for £53 per person are available. Travel duration is 26h 45m
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FlixBus22h 35m012:25MilanLampugnano Bus Station18:15SienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 08/07/2025 12:25:00 to Train Station, Siena (Italy) arriving at 08/07/2025 18:15:00. 50 Economy ticket for £19 per person are available. Travel duration is 5h 50m
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FlixBus16h 5m018:55SienaTrain Station11:00PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from Train Station, Siena (Italy) at 08/07/2025 18:55:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 09/07/2025 11:00:00. 50 Economy ticket for £49 per person are available. Travel duration is 16h 5m
Waiting Time 0h 40m -
Cheapest bus trips Wednesday
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FlixBus22h 5m012:55MilanLampugnano Bus Station11:00PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 09/07/2025 12:55:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 10/07/2025 11:00:00. 50 Economy ticket for £69 per person are available. Travel duration is 22h 5m
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FlixBus26h 25m012:00MilanSan Donato Bus Station14:25PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 09/07/2025 12:00:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 10/07/2025 14:25:00. 50 Economy ticket for £91 per person are available. Travel duration is 26h 25m
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FlixBus22h 55m015:30MilanLampugnano Bus Station14:25PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 09/07/2025 15:30:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 10/07/2025 14:25:00. 50 Economy ticket for £96 per person are available. Travel duration is 22h 55m
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MarinoBus24h 15m008:40MilanLampugnano Bus Station08:55PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from MarinoBus goes from Lampugnano Bus Station, Milan (Italy) at 09/07/2025 08:40:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 10/07/2025 08:55:00. 50 Economy ticket for £99 per person are available. Travel duration is 24h 15m
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MarinoBus23h 30m009:25MilanSan Donato Bus Station08:55PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from MarinoBus goes from San Donato Bus Station, Milan (Italy) at 09/07/2025 09:25:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 10/07/2025 08:55:00. 50 Economy ticket for £99 per person are available. Travel duration is 23h 30m
Cheapest bus trips Thursday
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FlixBus22h 5m012:55MilanLampugnano Bus Station11:00PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 10/07/2025 12:55:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 11/07/2025 11:00:00. 50 Economy ticket for £75 per person are available. Travel duration is 22h 5m
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FlixBus22h 55m015:30MilanLampugnano Bus Station14:25PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 10/07/2025 15:30:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 11/07/2025 14:25:00. 50 Economy ticket for £114 per person are available. Travel duration is 22h 55m
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FlixBus24h 0m014:25MilanSan Donato Bus Station14:25PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 10/07/2025 14:25:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 11/07/2025 14:25:00. 50 Economy ticket for £119 per person are available. Travel duration is 24h 0m
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FlixBus25h 20m009:40MilanSan Donato Bus Station11:00PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 10/07/2025 09:40:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 11/07/2025 11:00:00. 50 Economy ticket for £125 per person are available. Travel duration is 25h 20m
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FlixBus24h 55m018:30MilanSan Donato Bus Station19:25PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 10/07/2025 18:30:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 11/07/2025 19:25:00. 50 Economy ticket for £130 per person are available. Travel duration is 24h 55m
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FlixBus26h 40m008:20MilanLampugnano Bus Station14:55SienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 12/07/2025 08:20:00 to Train Station, Siena (Italy) arriving at 12/07/2025 14:55:00. 50 Economy ticket for £7 per person are available. Travel duration is 6h 35m
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FlixBus16h 5m018:55SienaTrain Station11:00PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from Train Station, Siena (Italy) at 12/07/2025 18:55:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 13/07/2025 11:00:00. 50 Economy ticket for £55 per person are available. Travel duration is 16h 5m
Waiting Time 4h 0m -
Cheapest bus trips Friday
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FlixBus22h 5m012:55MilanLampugnano Bus Station11:00PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 11/07/2025 12:55:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 12/07/2025 11:00:00. 50 Economy ticket for £66 per person are available. Travel duration is 22h 5m
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FlixBus22h 55m015:30MilanLampugnano Bus Station14:25PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 11/07/2025 15:30:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 12/07/2025 14:25:00. 50 Economy ticket for £114 per person are available. Travel duration is 22h 55m
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FlixBus25h 20m009:40MilanSan Donato Bus Station11:00PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 11/07/2025 09:40:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 12/07/2025 11:00:00. 50 Economy ticket for £123 per person are available. Travel duration is 25h 20m
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FlixBus23h 40m014:45MilanSan Donato Bus Station14:25PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 11/07/2025 14:45:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 12/07/2025 14:25:00. 50 Economy ticket for £125 per person are available. Travel duration is 23h 40m
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FlixBus24h 55m018:30MilanSan Donato Bus Station19:25PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 11/07/2025 18:30:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 12/07/2025 19:25:00. 50 Economy ticket for £128 per person are available. Travel duration is 24h 55m
Cheapest bus trips Saturday
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Autoservizi Salemi21h 45m010:00MilanLampugnano Bus Station07:45PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from Autoservizi Salemi goes from Lampugnano Bus Station, Milan (Italy) at 12/07/2025 10:00:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 13/07/2025 07:45:00. 50 Economy ticket for £76 per person are available. Travel duration is 21h 45m
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Autoservizi Salemi21h 0m010:45MilanSan Donato Bus Station07:45PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from Autoservizi Salemi goes from San Donato Bus Station, Milan (Italy) at 12/07/2025 10:45:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 13/07/2025 07:45:00. 50 Economy ticket for £76 per person are available. Travel duration is 21h 0m
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FlixBus22h 5m012:55MilanLampugnano Bus Station11:00PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 12/07/2025 12:55:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 13/07/2025 11:00:00. 50 Economy ticket for £93 per person are available. Travel duration is 22h 5m
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FlixBus25h 30m008:50MilanSan Donato Bus Station10:20PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 12/07/2025 08:50:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 13/07/2025 10:20:00. 50 Economy ticket for £110 per person are available. Travel duration is 25h 30m
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FlixBus21h 20m017:05MilanSan Donato Bus Station14:25PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 12/07/2025 17:05:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 13/07/2025 14:25:00. 50 Economy ticket for £111 per person are available. Travel duration is 21h 20m
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FlixBus26h 45mMilan10 km11:40CormanoCusano Milanino Bus Stop14:25PalermoVia Tommaso Fazello Bus Stop0 kmEconomyA Bus from FlixBus goes from Cusano Milanino Bus Stop, Cormano (Italy) at 12/07/2025 11:40:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 13/07/2025 14:25:00. 50 Economy ticket for £107 per person are available. Travel duration is 26h 45m
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FlixBus26h 40m008:20MilanLampugnano Bus Station14:55SienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 12/07/2025 08:20:00 to Train Station, Siena (Italy) arriving at 12/07/2025 14:55:00. 50 Economy ticket for £7 per person are available. Travel duration is 6h 35m
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FlixBus16h 5m018:55SienaTrain Station11:00PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from Train Station, Siena (Italy) at 12/07/2025 18:55:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 13/07/2025 11:00:00. 50 Economy ticket for £55 per person are available. Travel duration is 16h 5m
Waiting Time 4h 0m -
Cheapest bus trips Sunday
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Autoservizi Salemi21h 45m010:00MilanLampugnano Bus Station07:45PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from Autoservizi Salemi goes from Lampugnano Bus Station, Milan (Italy) at 13/07/2025 10:00:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 14/07/2025 07:45:00. 50 Economy ticket for £76 per person are available. Travel duration is 21h 45m
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Autoservizi Salemi21h 0m010:45MilanSan Donato Bus Station07:45PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from Autoservizi Salemi goes from San Donato Bus Station, Milan (Italy) at 13/07/2025 10:45:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 14/07/2025 07:45:00. 50 Economy ticket for £76 per person are available. Travel duration is 21h 0m
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FlixBus22h 5m012:55MilanLampugnano Bus Station11:00PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 13/07/2025 12:55:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 14/07/2025 11:00:00. 50 Economy ticket for £98 per person are available. Travel duration is 22h 5m
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FlixBus21h 20m017:05MilanSan Donato Bus Station14:25PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 13/07/2025 17:05:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 14/07/2025 14:25:00. 50 Economy ticket for £109 per person are available. Travel duration is 21h 20m
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FlixBus22h 5m016:20MilanLampugnano Bus Station14:25PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 13/07/2025 16:20:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 14/07/2025 14:25:00. 50 Economy ticket for £110 per person are available. Travel duration is 22h 5m
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FlixBus29h 35mMilan10 km08:50CormanoCusano Milanino Bus Stop14:25PalermoVia Tommaso Fazello Bus Stop0 kmEconomyA Bus from FlixBus goes from Cusano Milanino Bus Stop, Cormano (Italy) at 13/07/2025 08:50:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 14/07/2025 14:25:00. 50 Economy ticket for £91 per person are available. Travel duration is 29h 35m
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FlixBus26h 40m008:20MilanLampugnano Bus Station14:55SienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 12/07/2025 08:20:00 to Train Station, Siena (Italy) arriving at 12/07/2025 14:55:00. 50 Economy ticket for £7 per person are available. Travel duration is 6h 35m
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FlixBus16h 5m018:55SienaTrain Station11:00PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from Train Station, Siena (Italy) at 12/07/2025 18:55:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 13/07/2025 11:00:00. 50 Economy ticket for £55 per person are available. Travel duration is 16h 5m
Waiting Time 4h 0m -
What is the best day and time to travel by bus between Milan and Palermo?
All facts for Milan to Palermo bus at a glance
Compare all coach operators like FlixBus, Autoservizi Salemi and MarinoBus that travel daily 8 times by bus from Milan to Palermo in one click. Book your Milan to Palermo bus ticket starting from £66!
Cheapest Bus | £66 |
Fastest Bus | 21h 0m |
Earliest Coach | 08:50 |
Latest Coach | 18:30 |
Daily Bus Connections | 8 Ø |
Distance | 887.2 km |
Coach Companies | FlixBus, Autoservizi Salemi and MarinoBus |
What are the cheapest coach tickets from Milan to Palermo?
Every day, 8 buses from 3 coach companies leave Milan for Palermo. Check the table below to find the cheapest prices for coach tickets for this route, starting from 07/07/2025 and for the following days. Make sure get the cheapest bus ticket!
The cheapest time to travel from Milan to Palermo
How to save money travelling from Milan to Palermo
Book the ticket from Milan to Palermo in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the coach from Milan to Palermo, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Milan to Palermo are also emptier.Check for bus deals and promotions for all bus companies in this route. On CheckMyBus we show special offers directly in the coach trip on our search. Sign-up and check or deals sections and get notifications on our latest travel hacks.
All bus stations and stops in Milan and Palermo
Here is a map with all coach stations in Milan and Palermo. Compare which stop is closest to your destination to save time to find the fastest buses and connections.
Compare the bus with other modes of transport
All you need to know when you travel by bus from Milan to Palermo
FAQs for Milan to Palermo bus
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What equipment is available for the Milan Palermo bus route?
Available seat classes which are offered on the bus route Milan to Palermo
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
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