Which bus from Milan to Palermo is the best?
Check the bus schedule for Milan to Palermo. Here is a selection of the cheapest coach trips for the next days from bus operators like FlixBus, Autoservizi Salemi or MarinoBus. To see the full timetable for all coaches just use or search and compare.
Cheapest bus trips today
-
Autoservizi Salemi21h 45m010:00MilanLampugnano Bus Station07:45PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from Autoservizi Salemi goes from Lampugnano Bus Station, Milan (Italy) at 21/06/2025 10:00:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 22/06/2025 07:45:00. 50 Economy ticket for £75 per person are available. Travel duration is 21h 45m
-
Autoservizi Salemi21h 0m010:45MilanSan Donato Bus Station07:45PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from Autoservizi Salemi goes from San Donato Bus Station, Milan (Italy) at 21/06/2025 10:45:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 22/06/2025 07:45:00. 50 Economy ticket for £75 per person are available. Travel duration is 21h 0m
-
FlixBus22h 5m012:55MilanLampugnano Bus Station11:00PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 21/06/2025 12:55:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 22/06/2025 11:00:00. 50 Economy ticket for £107 per person are available. Travel duration is 22h 5m
-
MarinoBus24h 15m008:40MilanLampugnano Bus Station08:55PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from MarinoBus goes from Lampugnano Bus Station, Milan (Italy) at 21/06/2025 08:40:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 22/06/2025 08:55:00. 50 Economy ticket for £118 per person are available. Travel duration is 24h 15m
-
MarinoBus23h 30m009:25MilanSan Donato Bus Station08:55PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from MarinoBus goes from San Donato Bus Station, Milan (Italy) at 21/06/2025 09:25:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 22/06/2025 08:55:00. 50 Economy ticket for £118 per person are available. Travel duration is 23h 30m
Cheapest bus trips tomorrow
-
Autoservizi Salemi21h 45m010:00MilanLampugnano Bus Station07:45PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from Autoservizi Salemi goes from Lampugnano Bus Station, Milan (Italy) at 22/06/2025 10:00:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 23/06/2025 07:45:00. 50 Economy ticket for £72 per person are available. Travel duration is 21h 45m
-
MarinoBus24h 15m008:40MilanLampugnano Bus Station08:55PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from MarinoBus goes from Lampugnano Bus Station, Milan (Italy) at 22/06/2025 08:40:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 23/06/2025 08:55:00. 50 Economy ticket for £74 per person are available. Travel duration is 24h 15m
-
FlixBus22h 5m012:55MilanLampugnano Bus Station11:00PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 22/06/2025 12:55:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 23/06/2025 11:00:00. 50 Economy ticket for £84 per person are available. Travel duration is 22h 5m
-
FlixBus24h 55m018:30MilanSan Donato Bus Station19:25PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 22/06/2025 18:30:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 23/06/2025 19:25:00. 50 Economy ticket for £109 per person are available. Travel duration is 24h 55m
-
-
FlixBus26h 10m014:45MilanSan Donato Bus Station19:50SienaTrain Station0EconomyA Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 23/06/2025 14:45:00 to Train Station, Siena (Italy) arriving at 23/06/2025 19:50:00. 50 Economy ticket for £9 per person are available. Travel duration is 5h 5m
-
FlixBus19h 35m021:20SienaTrain Station16:55PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from Train Station, Siena (Italy) at 23/06/2025 21:20:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 24/06/2025 16:55:00. 50 Economy ticket for £53 per person are available. Travel duration is 19h 35m
Waiting Time 1h 30m -
Cheapest bus trips Monday
-
Autoservizi Salemi21h 45m010:00MilanLampugnano Bus Station07:45PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from Autoservizi Salemi goes from Lampugnano Bus Station, Milan (Italy) at 23/06/2025 10:00:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 24/06/2025 07:45:00. 50 Economy ticket for £68 per person are available. Travel duration is 21h 45m
-
Autoservizi Salemi21h 0m010:45MilanSan Donato Bus Station07:45PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from Autoservizi Salemi goes from San Donato Bus Station, Milan (Italy) at 23/06/2025 10:45:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 24/06/2025 07:45:00. 50 Economy ticket for £68 per person are available. Travel duration is 21h 0m
-
MarinoBus24h 15m008:40MilanLampugnano Bus Station08:55PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from MarinoBus goes from Lampugnano Bus Station, Milan (Italy) at 23/06/2025 08:40:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 24/06/2025 08:55:00. 50 Economy ticket for £80 per person are available. Travel duration is 24h 15m
-
MarinoBus23h 30m009:25MilanSan Donato Bus Station08:55PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from MarinoBus goes from San Donato Bus Station, Milan (Italy) at 23/06/2025 09:25:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 24/06/2025 08:55:00. 50 Economy ticket for £80 per person are available. Travel duration is 23h 30m
-
FlixBus22h 5m012:55MilanLampugnano Bus Station11:00PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 23/06/2025 12:55:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 24/06/2025 11:00:00. 50 Economy ticket for £81 per person are available. Travel duration is 22h 5m
Cheapest bus trips Tuesday
-
FlixBus22h 5m012:55MilanLampugnano Bus Station11:00PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 24/06/2025 12:55:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 25/06/2025 11:00:00. 50 Economy ticket for £62 per person are available. Travel duration is 22h 5m
-
Autoservizi Salemi21h 45m010:00MilanLampugnano Bus Station07:45PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from Autoservizi Salemi goes from Lampugnano Bus Station, Milan (Italy) at 24/06/2025 10:00:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 25/06/2025 07:45:00. 50 Economy ticket for £68 per person are available. Travel duration is 21h 45m
-
Autoservizi Salemi21h 0m010:45MilanSan Donato Bus Station07:45PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from Autoservizi Salemi goes from San Donato Bus Station, Milan (Italy) at 24/06/2025 10:45:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 25/06/2025 07:45:00. 50 Economy ticket for £68 per person are available. Travel duration is 21h 0m
-
FlixBus25h 25m015:30MilanLampugnano Bus Station16:55PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 24/06/2025 15:30:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 25/06/2025 16:55:00. 50 Economy ticket for £68 per person are available. Travel duration is 25h 25m
-
MarinoBus24h 15m008:40MilanLampugnano Bus Station08:55PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from MarinoBus goes from Lampugnano Bus Station, Milan (Italy) at 24/06/2025 08:40:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 25/06/2025 08:55:00. 50 Economy ticket for £79 per person are available. Travel duration is 24h 15m
Cheapest bus trips Wednesday
-
FlixBus22h 5m012:55MilanLampugnano Bus Station11:00PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 25/06/2025 12:55:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 26/06/2025 11:00:00. 50 Economy ticket for £64 per person are available. Travel duration is 22h 5m
-
FlixBus24h 55m018:30MilanSan Donato Bus Station19:25PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 25/06/2025 18:30:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 26/06/2025 19:25:00. 50 Economy ticket for £95 per person are available. Travel duration is 24h 55m
-
FlixBus25h 40m017:45MilanLampugnano Bus Station19:25PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 25/06/2025 17:45:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 26/06/2025 19:25:00. 50 Economy ticket for £95 per person are available. Travel duration is 25h 40m
-
FlixBus26h 25m012:00MilanSan Donato Bus Station14:25PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 25/06/2025 12:00:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 26/06/2025 14:25:00. 50 Economy ticket for £111 per person are available. Travel duration is 26h 25m
-
FlixBus22h 55m015:30MilanLampugnano Bus Station14:25PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 25/06/2025 15:30:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 26/06/2025 14:25:00. 50 Economy ticket for £124 per person are available. Travel duration is 22h 55m
Cheapest bus trips Thursday
-
Autoservizi Salemi21h 45m010:00MilanLampugnano Bus Station07:45PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from Autoservizi Salemi goes from Lampugnano Bus Station, Milan (Italy) at 26/06/2025 10:00:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 27/06/2025 07:45:00. 50 Economy ticket for £68 per person are available. Travel duration is 21h 45m
-
FlixBus22h 5m012:55MilanLampugnano Bus Station11:00PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 26/06/2025 12:55:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 27/06/2025 11:00:00. 50 Economy ticket for £73 per person are available. Travel duration is 22h 5m
-
MarinoBus24h 15m008:40MilanLampugnano Bus Station08:55PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from MarinoBus goes from Lampugnano Bus Station, Milan (Italy) at 26/06/2025 08:40:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 27/06/2025 08:55:00. 50 Economy ticket for £89 per person are available. Travel duration is 24h 15m
-
FlixBus24h 55m018:30MilanSan Donato Bus Station19:25PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 26/06/2025 18:30:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 27/06/2025 19:25:00. 50 Economy ticket for £117 per person are available. Travel duration is 24h 55m
Cheapest bus trips Friday
-
FlixBus22h 5m012:55MilanLampugnano Bus Station11:00PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 27/06/2025 12:55:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 28/06/2025 11:00:00. 50 Economy ticket for £73 per person are available. Travel duration is 22h 5m
-
FlixBus24h 55m018:30MilanSan Donato Bus Station19:25PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 27/06/2025 18:30:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 28/06/2025 19:25:00. 50 Economy ticket for £97 per person are available. Travel duration is 24h 55m
-
FlixBus25h 40m017:45MilanLampugnano Bus Station19:25PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 27/06/2025 17:45:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 28/06/2025 19:25:00. 50 Economy ticket for £97 per person are available. Travel duration is 25h 40m
-
FlixBus25h 20m009:40MilanSan Donato Bus Station11:00PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 27/06/2025 09:40:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 28/06/2025 11:00:00. 50 Economy ticket for £119 per person are available. Travel duration is 25h 20m
-
FlixBus25h 25m015:30MilanLampugnano Bus Station16:55PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 27/06/2025 15:30:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 28/06/2025 16:55:00. 50 Economy ticket for £119 per person are available. Travel duration is 25h 25m
-
-
FlixBus26h 10m014:45MilanSan Donato Bus Station19:50SienaTrain Station0EconomyA Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 23/06/2025 14:45:00 to Train Station, Siena (Italy) arriving at 23/06/2025 19:50:00. 50 Economy ticket for £9 per person are available. Travel duration is 5h 5m
-
FlixBus19h 35m021:20SienaTrain Station16:55PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from Train Station, Siena (Italy) at 23/06/2025 21:20:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 24/06/2025 16:55:00. 50 Economy ticket for £53 per person are available. Travel duration is 19h 35m
Waiting Time 1h 30m -
What is the best day and time to travel by bus between Milan and Palermo?
All facts for Milan to Palermo bus at a glance
Compare all coach operators like FlixBus, Autoservizi Salemi and MarinoBus that travel daily 9 times by bus from Milan to Palermo in one click. Book your Milan to Palermo bus ticket starting from £62!
Cheapest Bus | £62 |
Fastest Bus | 21h 0m |
Earliest Coach | 08:40 |
Latest Coach | 18:30 |
Daily Bus Connections | 9 Ø |
Distance | 887.2 km |
Coach Companies | FlixBus, Autoservizi Salemi and MarinoBus |
What are the cheapest coach tickets from Milan to Palermo?
Every day, 9 buses from 3 coach companies leave Milan for Palermo. Check the table below to find the cheapest prices for coach tickets for this route, starting from 21/06/2025 and for the following days. Make sure get the cheapest bus ticket!
The cheapest time to travel from Milan to Palermo
How to save money travelling from Milan to Palermo
Book the ticket from Milan to Palermo in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the coach from Milan to Palermo, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Milan to Palermo are also emptier.Check for bus deals and promotions for all bus companies in this route. On CheckMyBus we show special offers directly in the coach trip on our search. Sign-up and check or deals sections and get notifications on our latest travel hacks.
All bus stations and stops in Milan and Palermo
Here is a map with all coach stations in Milan and Palermo. Compare which stop is closest to your destination to save time to find the fastest buses and connections.
Compare the bus with other modes of transport
All you need to know when you travel by bus from Milan to Palermo
FAQs for Milan to Palermo bus
How much does a Milan Palermo coach trip cost?
How much could I save by comparing buses from Milan to Palermo?
How many connections are available for the Milan Palermo route on average every day?
How long does a bus to Palermo from Milan take?
What time is the first bus from Milan to Palermo?
What time is the last coach from Milan to Palermo?
Which bus companies serve the Milan Palermo route?
Is there a direct bus between Milan and Palermo?
What can I take with me on the bus to Palermo from Milan?
What equipment is available for the Milan Palermo bus route?
Available seat classes which are offered on the bus route Milan to Palermo
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
More bus routes to Milan and to Palermo
- Bus Routes to Milan
- Bus to Milan from Amsterdam
- Bus from Ancona to Milan
- Bologna to Milan bus
- Breuil-Cervinia to Milan coach
- Bus to Milan from Castrovillari
- Bus from Ciro Marina to Milan
- Coach to Milan from Como
- Coach Courmayeur to Milan
- Buses Kosice to Milan
- Coach from London to Milan
- Nantes to Milan bus
- Coach from Passo del Tonale to Milan
- Ponte di Legno to Milan bus
- Bus to Milan from Rome
- Coach Sibari to Milan
- Bus to Milan from Soverato
- Turin to Milan coach
- Coach to Milan from Venice
- Coach to Milan from Verona
- Villa San Giovanni to Milan bus
- Bus Routes to Palermo
- Bus to Palermo from Agrigento
- Bus Caltanissetta to Palermo
- Bus from Castelvetrano to Palermo
- Bus to Palermo from Catania
- Cosenza to Palermo bus
- Bus from Foggia to Palermo
- Coach Licata to Palermo
- Coaches Marsala to Palermo
- Coach Mazara del Vallo to Palermo
- Milazzo to Palermo coach
- Bus to Palermo from Naples
- Piazza Armerina to Palermo bus
- Ragusa to Palermo coach
- Bus Rome to Palermo
- Coach from Siracusa to Palermo
- Buses Taormina to Palermo
- Trapani to Palermo bus
- Bus Turin to Palermo