Bus tickets Milan to Palermo from £66

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Which bus from Milan to Palermo is the best?

Check the bus schedule for Milan to Palermo. Here is a selection of the cheapest coach trips for the next days from bus operators like FlixBus, Autoservizi Salemi or MarinoBus. To see the full timetable for all coaches just use or search and compare.

today
from £108
tomorrow
from £76
Wednesday
from £69
Thursday
from £75
Friday
from £66
Saturday
from £76
Sunday
from £76

Cheapest bus trips today

Prices are for one way and one person
  • FlixBus
    22h 5m
    0
    12:55
    Milan
    Lampugnano Bus Station
    11:00
    Palermo
    Via Tommaso Fazello Bus Stop
    0
    FlixBus
    Economy
    £108
  • FlixBus
    25h 25m
    0
    15:30
    Milan
    Lampugnano Bus Station
    16:55
    Palermo
    Via Tommaso Fazello Bus Stop
    0
    FlixBus
    Economy
    £109
  • FlixBus
    26h 10m
    0
    14:45
    Milan
    San Donato Bus Station
    16:55
    Palermo
    Via Tommaso Fazello Bus Stop
    0
    FlixBus
    Economy
    £129
  • FlixBus
    23h 50m
    0
    10:30
    Milan
    Lampugnano Bus Station
    10:20
    Palermo
    Via Tommaso Fazello Bus Stop
    0
    FlixBus
    Economy
    £130
  • FlixBus
    25h 20m
    0
    09:40
    Milan
    San Donato Bus Station
    11:00
    Palermo
    Via Tommaso Fazello Bus Stop
    0
    FlixBus
    Economy
    £131
  • Did you know that if you travel from Milan to Palermo via Siena, you can save more than £40? You can find the corresponding connections below.
    • FlixBus
      22h 35m
      0
      12:25
      Milan
      Lampugnano Bus Station
      18:15
      Siena
      Train Station
      0
      FlixBus
      Economy
      £19
      • Waiting Time 0h 40m
    • FlixBus
      16h 5m
      0
      18:55
      Siena
      Train Station
      11:00
      Palermo
      Via Tommaso Fazello Bus Stop
      0
      FlixBus
      Economy
      £49
    Travel time is 0h 30m longer, but you will save £40

Cheapest bus trips tomorrow

Prices are for one way and one person
  • Autoservizi Salemi
    21h 45m
    0
    10:00
    Milan
    Lampugnano Bus Station
    07:45
    Palermo
    Via Tommaso Fazello Bus Stop
    0
    Autoservizi Salemi
    Economy
    £76
  • Autoservizi Salemi
    21h 0m
    0
    10:45
    Milan
    San Donato Bus Station
    07:45
    Palermo
    Via Tommaso Fazello Bus Stop
    0
    Autoservizi Salemi
    Economy
    £76
  • FlixBus
    22h 5m
    0
    12:55
    Milan
    Lampugnano Bus Station
    11:00
    Palermo
    Via Tommaso Fazello Bus Stop
    0
    FlixBus
    Economy
    £85
  • MarinoBus
    24h 15m
    0
    08:40
    Milan
    Lampugnano Bus Station
    08:55
    Palermo
    Via Tommaso Fazello Bus Stop
    0
    MarinoBus
    Economy
    £93
  • MarinoBus
    23h 30m
    0
    09:25
    Milan
    San Donato Bus Station
    08:55
    Palermo
    Via Tommaso Fazello Bus Stop
    0
    MarinoBus
    Economy
    £93
  • Did you know that if you travel from Milan to Palermo via Cormano, you can save more than £23? You will find the corresponding connections below.
    • FlixBus
      Save more than 30%
      26h 45m
      Milan
      10 km
      11:40
      Cormano
      Cusano Milanino Bus Stop
      14:25
      Palermo
      Via Tommaso Fazello Bus Stop
      0 km
      FlixBus
      Economy
      £53
  • Did you know that if you travel from Milan to Palermo via Siena, you can save more than £8? You can find the corresponding connections below.
    • FlixBus
      22h 35m
      0
      12:25
      Milan
      Lampugnano Bus Station
      18:15
      Siena
      Train Station
      0
      FlixBus
      Economy
      £19
      • Waiting Time 0h 40m
    • FlixBus
      16h 5m
      0
      18:55
      Siena
      Train Station
      11:00
      Palermo
      Via Tommaso Fazello Bus Stop
      0
      FlixBus
      Economy
      £49
    Travel time is 1h 35m longer, but you will save £8

Cheapest bus trips Wednesday

Prices are for one way and one person
  • FlixBus
    22h 5m
    0
    12:55
    Milan
    Lampugnano Bus Station
    11:00
    Palermo
    Via Tommaso Fazello Bus Stop
    0
    FlixBus
    Economy
    £69
  • FlixBus
    26h 25m
    0
    12:00
    Milan
    San Donato Bus Station
    14:25
    Palermo
    Via Tommaso Fazello Bus Stop
    0
    FlixBus
    Economy
    £91
  • FlixBus
    22h 55m
    0
    15:30
    Milan
    Lampugnano Bus Station
    14:25
    Palermo
    Via Tommaso Fazello Bus Stop
    0
    FlixBus
    Economy
    £96
  • MarinoBus
    24h 15m
    0
    08:40
    Milan
    Lampugnano Bus Station
    08:55
    Palermo
    Via Tommaso Fazello Bus Stop
    0
    MarinoBus
    Economy
    £99
  • MarinoBus
    23h 30m
    0
    09:25
    Milan
    San Donato Bus Station
    08:55
    Palermo
    Via Tommaso Fazello Bus Stop
    0
    MarinoBus
    Economy
    £99

Cheapest bus trips Thursday

Prices are for one way and one person
  • FlixBus
    22h 5m
    0
    12:55
    Milan
    Lampugnano Bus Station
    11:00
    Palermo
    Via Tommaso Fazello Bus Stop
    0
    FlixBus
    Economy
    £75
  • FlixBus
    22h 55m
    0
    15:30
    Milan
    Lampugnano Bus Station
    14:25
    Palermo
    Via Tommaso Fazello Bus Stop
    0
    FlixBus
    Economy
    £114
  • FlixBus
    24h 0m
    0
    14:25
    Milan
    San Donato Bus Station
    14:25
    Palermo
    Via Tommaso Fazello Bus Stop
    0
    FlixBus
    Economy
    £119
  • FlixBus
    25h 20m
    0
    09:40
    Milan
    San Donato Bus Station
    11:00
    Palermo
    Via Tommaso Fazello Bus Stop
    0
    FlixBus
    Economy
    £125
  • FlixBus
    24h 55m
    0
    18:30
    Milan
    San Donato Bus Station
    19:25
    Palermo
    Via Tommaso Fazello Bus Stop
    0
    FlixBus
    Economy
    £130
  • Did you know that if you travel from Milan to Palermo via Siena, you can save more than £13? You can find the corresponding connections below.
    • FlixBus
      26h 40m
      0
      08:20
      Milan
      Lampugnano Bus Station
      14:55
      Siena
      Train Station
      0
      FlixBus
      Economy
      £7
      • Waiting Time 4h 0m
    • FlixBus
      16h 5m
      0
      18:55
      Siena
      Train Station
      11:00
      Palermo
      Via Tommaso Fazello Bus Stop
      0
      FlixBus
      Economy
      £55
    Travel time is 4h 35m longer, but you will save £13

Cheapest bus trips Friday

Prices are for one way and one person
  • FlixBus
    22h 5m
    0
    12:55
    Milan
    Lampugnano Bus Station
    11:00
    Palermo
    Via Tommaso Fazello Bus Stop
    0
    FlixBus
    Economy
    £66
  • FlixBus
    22h 55m
    0
    15:30
    Milan
    Lampugnano Bus Station
    14:25
    Palermo
    Via Tommaso Fazello Bus Stop
    0
    FlixBus
    Economy
    £114
  • FlixBus
    25h 20m
    0
    09:40
    Milan
    San Donato Bus Station
    11:00
    Palermo
    Via Tommaso Fazello Bus Stop
    0
    FlixBus
    Economy
    £123
  • FlixBus
    23h 40m
    0
    14:45
    Milan
    San Donato Bus Station
    14:25
    Palermo
    Via Tommaso Fazello Bus Stop
    0
    FlixBus
    Economy
    £125
  • FlixBus
    24h 55m
    0
    18:30
    Milan
    San Donato Bus Station
    19:25
    Palermo
    Via Tommaso Fazello Bus Stop
    0
    FlixBus
    Economy
    £128

Cheapest bus trips Saturday

Prices are for one way and one person
  • Autoservizi Salemi
    21h 45m
    0
    10:00
    Milan
    Lampugnano Bus Station
    07:45
    Palermo
    Via Tommaso Fazello Bus Stop
    0
    Autoservizi Salemi
    Economy
    £76
  • Autoservizi Salemi
    21h 0m
    0
    10:45
    Milan
    San Donato Bus Station
    07:45
    Palermo
    Via Tommaso Fazello Bus Stop
    0
    Autoservizi Salemi
    Economy
    £76
  • FlixBus
    22h 5m
    0
    12:55
    Milan
    Lampugnano Bus Station
    11:00
    Palermo
    Via Tommaso Fazello Bus Stop
    0
    FlixBus
    Economy
    £93
  • FlixBus
    25h 30m
    0
    08:50
    Milan
    San Donato Bus Station
    10:20
    Palermo
    Via Tommaso Fazello Bus Stop
    0
    FlixBus
    Economy
    £110
  • FlixBus
    21h 20m
    0
    17:05
    Milan
    San Donato Bus Station
    14:25
    Palermo
    Via Tommaso Fazello Bus Stop
    0
    FlixBus
    Economy
    £111
  • Did you know that if you travel from Milan to Palermo via Cormano, you can save more than £-31? You will find the corresponding connections below.
    • FlixBus
      26h 45m
      Milan
      10 km
      11:40
      Cormano
      Cusano Milanino Bus Stop
      14:25
      Palermo
      Via Tommaso Fazello Bus Stop
      0 km
      FlixBus
      Economy
      £107
  • Did you know that if you travel from Milan to Palermo via Siena, you can save more than £14? You can find the corresponding connections below.
    • FlixBus
      26h 40m
      0
      08:20
      Milan
      Lampugnano Bus Station
      14:55
      Siena
      Train Station
      0
      FlixBus
      Economy
      £7
      • Waiting Time 4h 0m
    • FlixBus
      16h 5m
      0
      18:55
      Siena
      Train Station
      11:00
      Palermo
      Via Tommaso Fazello Bus Stop
      0
      FlixBus
      Economy
      £55
    Travel time is 5h 40m longer, but you will save £14

Cheapest bus trips Sunday

Prices are for one way and one person
  • Autoservizi Salemi
    21h 45m
    0
    10:00
    Milan
    Lampugnano Bus Station
    07:45
    Palermo
    Via Tommaso Fazello Bus Stop
    0
    Autoservizi Salemi
    Economy
    £76
  • Autoservizi Salemi
    21h 0m
    0
    10:45
    Milan
    San Donato Bus Station
    07:45
    Palermo
    Via Tommaso Fazello Bus Stop
    0
    Autoservizi Salemi
    Economy
    £76
  • FlixBus
    22h 5m
    0
    12:55
    Milan
    Lampugnano Bus Station
    11:00
    Palermo
    Via Tommaso Fazello Bus Stop
    0
    FlixBus
    Economy
    £98
  • FlixBus
    21h 20m
    0
    17:05
    Milan
    San Donato Bus Station
    14:25
    Palermo
    Via Tommaso Fazello Bus Stop
    0
    FlixBus
    Economy
    £109
  • FlixBus
    22h 5m
    0
    16:20
    Milan
    Lampugnano Bus Station
    14:25
    Palermo
    Via Tommaso Fazello Bus Stop
    0
    FlixBus
    Economy
    £110
  • Did you know that if you travel from Milan to Palermo via Cormano, you can save more than £-15? You will find the corresponding connections below.
    • FlixBus
      29h 35m
      Milan
      10 km
      08:50
      Cormano
      Cusano Milanino Bus Stop
      14:25
      Palermo
      Via Tommaso Fazello Bus Stop
      0 km
      FlixBus
      Economy
      £91
  • Did you know that if you travel from Milan to Palermo via Siena, you can save more than £14? You can find the corresponding connections below.
    • FlixBus
      26h 40m
      0
      08:20
      Milan
      Lampugnano Bus Station
      14:55
      Siena
      Train Station
      0
      FlixBus
      Economy
      £7
      • Waiting Time 4h 0m
    • FlixBus
      16h 5m
      0
      18:55
      Siena
      Train Station
      11:00
      Palermo
      Via Tommaso Fazello Bus Stop
      0
      FlixBus
      Economy
      £55
    Travel time is 5h 40m longer, but you will save £14

What is the best day and time to travel by bus between Milan and Palermo?

Here is the frequency of all coach connections from Milan to Palermo. See on which day of the week you have more travel options and what time you have more bus trips to choose from.
Saturday is the busiest day, with more than 10 daily coaches from Milan to Palermo. Monday has instead the fewest connections, with only 6 daily coaches between Milan and Palermo.
The busiest time of the day is the Afternoon, with 28 coaches from Milan to Palermo, while Evening sees the fewest connections between Milan and Palermo, with 5 offers.

All facts for Milan to Palermo bus at a glance

Compare all coach operators like FlixBus, Autoservizi Salemi and MarinoBus that travel daily 8 times by bus from Milan to Palermo in one click. Book your Milan to Palermo bus ticket starting from £66!

Cheapest Bus £66
Fastest Bus 21h 0m
Earliest Coach 08:50
Latest Coach 18:30
Daily Bus Connections 8 Ø
Distance 887.2 km
Coach Companies FlixBus, Autoservizi Salemi and MarinoBus

What are the cheapest coach tickets from Milan to Palermo?

Every day, 8 buses from 3 coach companies leave Milan for Palermo. Check the table below to find the cheapest prices for coach tickets for this route, starting from 07/07/2025 and for the following days. Make sure get the cheapest bus ticket!

Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday
Monday 07/07
£108
Tuesday 08/07
£85
Wednesday 09/07
£69
Thursday 10/07
£75
Friday 11/07
£66
Saturday 12/07
£93
Sunday 13/07
£98
Monday 14/07
£71
Tuesday 15/07
£66
Wednesday 16/07
£80
Thursday 17/07
£88
Friday 18/07
£85
Saturday 19/07
£85
Sunday 20/07
£93
Monday 21/07
£82
Tuesday 22/07
£104
Wednesday 23/07
£91
Thursday 24/07
£82
Friday 25/07
£94
Saturday 26/07
£100
Sunday 27/07
£90
Monday 28/07
£72
Tuesday 29/07
£84
Wednesday 30/07
£87
Thursday 31/07
£78
Friday 01/08
£75
Saturday 02/08
£85
Sunday 03/08

The cheapest time to travel from Milan to Palermo

See here on which day and which time of the day you can find the cheapest bus ticket from Milan to Palermo, for the next 30 days.
With a price starting from £66, Friday is the cheapest day for a coach from Milan to Palermo. Monday instead is the most expensive day with prices starting from £108.
Afternoon is the cheapest day time for bus tickets from Milan to Palermo, with £66. Evening is the most expensive time of the day with prices starting from £127.

How to save money travelling from Milan to Palermo

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying higher prices for your trip? Plan your bus trips smartly. Here are a few hacks to save money on your coach journey.

Book the ticket from Milan to Palermo in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the coach from Milan to Palermo, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Milan to Palermo are also emptier.

Check for bus deals and promotions for all bus companies in this route. On CheckMyBus we show special offers directly in the coach trip on our search. Sign-up and check or deals sections and get notifications on our latest travel hacks.

All bus stations and stops in Milan and Palermo

Here is a map with all coach stations in Milan and Palermo. Compare which stop is closest to your destination to save time to find the fastest buses and connections.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Milan to Palermo? Compare all modes of transports from Milan to Palermo.

All you need to know when you travel by bus from Milan to Palermo

Check all information on comfort and services on the coaches from Milan to Palermo. Which seat classes are available or what are the amenities of operators on your coach trip? Below you´ll find answers to your questions.

FAQs for Milan to Palermo bus

How much does a Milan Palermo coach trip cost?

This depends on, among other things, the day and travel time. The cheapest ticket for the Milan Palermo bus trip is available from £66 and takes 22h 5m. Compare offers and save money!

How much could I save by comparing buses from Milan to Palermo?

This connection is offered by 3 companies with ticket prices ranging from £66 to £150. Therefore, we suggest booking your ticket as soon as possible to ensure you’ll get the cheapest bus trip to Palermo.

How many connections are available for the Milan Palermo route on average every day?

Each day, the bus route from Milan to Palermo is offered by roughly 8 busses. By using our search, you can compare bus schedules and find your ideal trip.

How long does a bus to Palermo from Milan take?

The quickest coach from Milan to Palermo is provided by Autoservizi Salemi and takes 21h 0m. Coach tickets for this connection cost £76. However, keep in mind that the connection can take longer due to traffic.

What time is the first bus from Milan to Palermo?

The earliest bus to Palermo departs from Milan at 08:50. In this context, information about departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

What time is the last coach from Milan to Palermo?

The latest bus to Palermo departs from Milan at 18:30. Please note that departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

Which bus companies serve the Milan Palermo route?

Passengers looking to travel from Milan to Palermo can travel with FlixBus, Autoservizi Salemi and MarinoBus. Compare all available bus tickets with our search to book the trip that works best for you.

Is there a direct bus between Milan and Palermo?

You can check all the direct connections between Milan and Palermo by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus, Autoservizi Salemi and MarinoBus.

What can I take with me on the bus to Palermo from Milan?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the bus for the Milan Palermo bus route free of charge. Simply use our search to find a coach that is best suited to your needs for your planned travel date.

What equipment is available for the Milan Palermo bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make travelling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Milan to Palermo on your planned travel date.

Available seat classes which are offered on the bus route Milan to Palermo

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Milan and to Palermo

Here’s an overview of the most popular bus routes to Milan and to Palermo. Simply click on the connection of your choice, and you’ll find all the details about your bus route!
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Popular Airport Transfers to Milan and to Palermo
CheckMyBus › Coaches in Italy › Coach to Milan › Coach to Palermo

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