Which bus from Milan to Palermo is the cheapest?

Compare all coach companies and find the best price: Bus tickets from £29
Search for your destination Millions of deals worldwide
Compare results Save up to 70%
Find the right bus for you Easy and transparent

Which bus from Milan to Palermo is the best?

Check the bus schedule for Milan to Palermo. Here is a selection of the cheapest coach trips for the next days from bus operators like FlixBus or Autoservizi Salemi. To see the full timetable for all coaches just use or search and compare.

today
£57
tomorrow
£51
Friday
£57
Saturday
£53
Sunday
£53
Monday
£40
Tuesday
£29

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 21h 55m 13:05 Milan Lampugnano Bus Station 11:00 Palermo Via Tommaso Fazello Bus Stop  Economy £57
FlixBus 24h 50m 18:30 Milan San Donato Bus Station 19:20 Palermo Via Tommaso Fazello Bus Stop  Economy £59
FlixBus 25h 35m 17:45 Milan Lampugnano Bus Station 19:20 Palermo Via Tommaso Fazello Bus Stop  Economy £60
Autoservizi Salemi 21h 0m 10:45 Milan San Donato Bus Station 07:45 Palermo Via Tommaso Fazello Bus Stop  Economy £75
  • Did you know that if you travel from Milan to Palermo via Assago, you can save more than £-12? You will find the corresponding connections below.
    • FlixBus
      25h 55m
      Milan
      8 km
      09:05
      Assago
      Milanofiori Forum
      11:00
      Palermo
      Via Tommaso Fazello Bus Stop
      0 km
      FlixBus
      Economy
      £69

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 21h 55m 13:05 Milan Lampugnano Bus Station 11:00 Palermo Via Tommaso Fazello Bus Stop  Economy £51
FlixBus 25h 20m 09:40 Milan San Donato Bus Station 11:00 Palermo Via Tommaso Fazello Bus Stop  Economy £64
FlixBus 21h 50m 17:25 Milan San Donato Bus Station 15:15 Palermo Via Tommaso Fazello Bus Stop  Economy £66
FlixBus 22h 35m 16:40 Milan Lampugnano Bus Station 15:15 Palermo Via Tommaso Fazello Bus Stop  Economy £66
FlixBus 24h 50m 18:30 Milan San Donato Bus Station 19:20 Palermo Via Tommaso Fazello Bus Stop  Economy £73
  • Did you know that if you travel from Milan to Palermo via Assago, you can save more than £-11? You will find the corresponding connections below.
    • FlixBus
      25h 55m
      Milan
      8 km
      09:05
      Assago
      Milanofiori Forum
      11:00
      Palermo
      Via Tommaso Fazello Bus Stop
      0 km
      FlixBus
      Economy
      £62
  • Did you know that if you travel from Milan to Palermo via Siena, you can save more than £5? You can find the corresponding connections below.
    • Itabus
      32h 40m
      0
      10:40
      Milan
      Lampugnano Bus Station
      16:20
      Siena
      Train Station
      0
      Itabus
      Premium Economy
      £7
      • Waiting Time 6h 5m
    • FlixBus
      20h 55m
      0
      22:25
      Siena
      Train Station
      19:20
      Palermo
      Via Tommaso Fazello Bus Stop
      0
      FlixBus
      Economy
      £39
    Travel time is 10h 50m longer, but you will save £5

Cheapest bus trips Friday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 21h 55m 13:05 Milan Lampugnano Bus Station 11:00 Palermo Via Tommaso Fazello Bus Stop  Economy £57
FlixBus 22h 15m 12:45 Milan San Donato Bus Station 11:00 Palermo Via Tommaso Fazello Bus Stop  Economy £59
FlixBus 21h 50m 17:25 Milan San Donato Bus Station 15:15 Palermo Via Tommaso Fazello Bus Stop  Economy £63
Autoservizi Salemi 21h 45m 10:00 Milan Lampugnano Bus Station 07:45 Palermo Via Tommaso Fazello Bus Stop  Economy £75
Autoservizi Salemi 21h 0m 10:45 Milan San Donato Bus Station 07:45 Palermo Via Tommaso Fazello Bus Stop  Economy £75
  • Did you know that if you travel from Milan to Palermo via Assago, you can save more than £5? You will find the corresponding connections below.
    • FlixBus
      Save more than 9%
      25h 55m
      Milan
      8 km
      09:05
      Assago
      Milanofiori Forum
      11:00
      Palermo
      Via Tommaso Fazello Bus Stop
      0 km
      FlixBus
      Economy
      £52
  • Did you know that if you travel from Milan to Palermo via Siena, you can save more than £6? You can find the corresponding connections below.
    • Itabus
      24h 20m
      0
      10:40
      Milan
      Lampugnano Bus Station
      16:20
      Siena
      Train Station
      0
      Itabus
      Premium Economy
      £7
      • Waiting Time 2h 40m
    • FlixBus
      16h 0m
      0
      19:00
      Siena
      Train Station
      11:00
      Palermo
      Via Tommaso Fazello Bus Stop
      0
      FlixBus
      Economy
      £45
    Travel time is 3h 20m longer, but you will save £6

Cheapest bus trips Saturday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 24h 50m 18:30 Milan San Donato Bus Station 19:20 Palermo Via Tommaso Fazello Bus Stop  Economy £53
FlixBus 25h 35m 17:45 Milan Lampugnano Bus Station 19:20 Palermo Via Tommaso Fazello Bus Stop  Economy £53
FlixBus 21h 50m 17:25 Milan San Donato Bus Station 15:15 Palermo Via Tommaso Fazello Bus Stop  Economy £57
FlixBus 22h 35m 16:40 Milan Lampugnano Bus Station 15:15 Palermo Via Tommaso Fazello Bus Stop  Economy £57
FlixBus 25h 20m 09:40 Milan San Donato Bus Station 11:00 Palermo Via Tommaso Fazello Bus Stop  Economy £59
  • Did you know that if you travel from Milan to Palermo via Assago, you can save more than £-4? You will find the corresponding connections below.
    • FlixBus
      23h 10m
      Milan
      8 km
      16:05
      Assago
      Milanofiori Forum
      15:15
      Palermo
      Via Tommaso Fazello Bus Stop
      0 km
      FlixBus
      Economy
      £57
  • Did you know that if you travel from Milan to Palermo via Rome Fiumicino Airport, you can save more than £12? You can find the corresponding connections below.
    • Itabus
      31h 20m
      0
      00:30
      Milan
      San Donato Bus Station
      12:20
      Rome Fiumicino Airport
      Rome Fiumicino Airport
      0
      Itabus
      Economy
      £19
      • Waiting Time 5h 0m
    • Itabus
      14h 30m
      0
      17:20
      Rome Fiumicino Airport
      Rome Fiumicino Airport
      07:50
      Palermo
      Piazza Cairoli Bus Station
      0
      Itabus
      Economy
      £22
    Travel time is 9h 30m longer, but you will save £12

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 24h 50m 18:30 Milan San Donato Bus Station 19:20 Palermo Via Tommaso Fazello Bus Stop  Economy £53
FlixBus 25h 35m 17:45 Milan Lampugnano Bus Station 19:20 Palermo Via Tommaso Fazello Bus Stop  Economy £53
FlixBus 25h 0m 10:00 Milan San Donato Bus Station 11:00 Palermo Via Tommaso Fazello Bus Stop  Economy £64
FlixBus 21h 55m 13:05 Milan Lampugnano Bus Station 11:00 Palermo Via Tommaso Fazello Bus Stop  Economy £64
FlixBus 21h 50m 17:25 Milan San Donato Bus Station 15:15 Palermo Via Tommaso Fazello Bus Stop  Economy £74
  • Did you know that if you travel from Milan to Palermo via Assago, you can save more than £-8? You will find the corresponding connections below.
    • FlixBus
      25h 55m
      Milan
      8 km
      09:05
      Assago
      Milanofiori Forum
      11:00
      Palermo
      Via Tommaso Fazello Bus Stop
      0 km
      FlixBus
      Economy
      £61
  • Did you know that if you travel from Milan to Palermo via Rome Fiumicino Airport, you can save more than £12? You can find the corresponding connections below.
    • Itabus
      31h 20m
      0
      00:30
      Milan
      San Donato Bus Station
      12:20
      Rome Fiumicino Airport
      Rome Fiumicino Airport
      0
      Itabus
      Economy
      £19
      • Waiting Time 5h 0m
    • Itabus
      14h 30m
      0
      17:20
      Rome Fiumicino Airport
      Rome Fiumicino Airport
      07:50
      Palermo
      Piazza Cairoli Bus Station
      0
      Itabus
      Economy
      £22
    Travel time is 9h 30m longer, but you will save £12

Cheapest bus trips Monday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 24h 30m 14:45 Milan San Donato Bus Station 15:15 Palermo Via Tommaso Fazello Bus Stop  Economy £40
FlixBus 25h 35m 17:45 Milan Lampugnano Bus Station 19:20 Palermo Via Tommaso Fazello Bus Stop  Economy £40
FlixBus 24h 50m 18:30 Milan San Donato Bus Station 19:20 Palermo Via Tommaso Fazello Bus Stop  Economy £41
Autoservizi Salemi 21h 0m 10:45 Milan San Donato Bus Station 07:45 Palermo Via Tommaso Fazello Bus Stop  Economy £69

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 24h 50m 18:30 Milan San Donato Bus Station 19:20 Palermo Via Tommaso Fazello Bus Stop  Economy £29
FlixBus 25h 35m 17:45 Milan Lampugnano Bus Station 19:20 Palermo Via Tommaso Fazello Bus Stop  Economy £29
FlixBus 21h 50m 17:25 Milan San Donato Bus Station 15:15 Palermo Via Tommaso Fazello Bus Stop  Economy £36
FlixBus 22h 35m 16:40 Milan Lampugnano Bus Station 15:15 Palermo Via Tommaso Fazello Bus Stop  Economy £37
FlixBus 26h 10m 08:50 Milan San Donato Bus Station 11:00 Palermo Via Tommaso Fazello Bus Stop  Economy £39

Best Price Offer: The price for the cheapest coach from Milan to Palermo is £29 on 22/09/2026. Flexible travellers save on ticket prices.


What is the best day and time to travel by bus between Milan and Palermo?

Here is the frequency of all coach connections from Milan to Palermo. See on which day of the week you have more travel options and what time you have more bus trips to choose from.
Friday is the busiest day, with more than 9 daily coaches from Milan to Palermo. Tuesday has instead the fewest connections, with only 6 daily coaches between Milan and Palermo.
The busiest time of the day is the Afternoon, with 36 coaches from Milan to Palermo, while Evening sees the fewest connections between Milan and Palermo, with 7 offers.

All facts for Milan to Palermo bus at a glance

Compare all coach operators like FlixBus and Autoservizi Salemi that travel daily 7 times by bus from Milan to Palermo in one click. Book your Milan to Palermo bus ticket starting from £29!

Cheapest Bus £29
Fastest Bus 21h 0m
Earliest Coach 10:45
Latest Coach 18:30
Daily Bus Connections 7 Ø
Distance 887.2 km
Coach Companies FlixBus and Autoservizi Salemi

What are the cheapest coach tickets from Milan to Palermo?

Every day, 7 buses from 2 coach companies leave Milan for Palermo. Check the table below to find the cheapest prices for coach tickets for this route, starting from 16/09/2026 and for the following days. Make sure get the cheapest bus ticket!

Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday
Monday 14/09
Tuesday 15/09
Wednesday 16/09
£59
Thursday 17/09
£64
Friday 18/09
£59
Saturday 19/09
£53
Sunday 20/09
£53
Monday 21/09
£40
Tuesday 22/09
£29
Wednesday 23/09
£41
Thursday 24/09
£42
Friday 25/09
£57
Saturday 26/09
£36
Sunday 27/09
£56
Monday 28/09
£44
Tuesday 29/09
£48
Wednesday 30/09
£39
Thursday 01/10
£55
Friday 02/10
£41
Saturday 03/10
£51
Sunday 04/10
£45
Monday 05/10
£52
Tuesday 06/10
£36
Wednesday 07/10
£51
Thursday 08/10
£52
Friday 09/10
£49
Saturday 10/10
£45
Sunday 11/10

The cheapest time to travel from Milan to Palermo

See here on which day and which time of the day you can find the cheapest bus ticket from Milan to Palermo, for the next 30 days.
With a price starting from £29, Tuesday is the cheapest day for a coach from Milan to Palermo. Sunday instead is the most expensive day with prices starting from £45.
Afternoon is the cheapest day time for bus tickets from Milan to Palermo, with £29. Morning is the most expensive time of the day with prices starting from £39.

How to save money travelling from Milan to Palermo

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying higher prices for your trip? Plan your bus trips smartly. Here are a few hacks to save money on your coach journey.

Book the ticket from Milan to Palermo in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the coach from Milan to Palermo, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Milan to Palermo are also emptier.

Check for bus deals and promotions for all bus companies in this route. On CheckMyBus we show special offers directly in the coach trip on our search. Sign-up and check or deals sections and get notifications on our latest travel hacks.

All bus stations and stops in Milan and Palermo

Here is a map with all coach stations in Milan and Palermo. Compare which stop is closest to your destination to save time to find the fastest buses and connections.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Milan to Palermo? Compare all modes of transports from Milan to Palermo.

All you need to know when you travel by bus from Milan to Palermo

Check all information on comfort and services on the coaches from Milan to Palermo. Which seat classes are available or what are the amenities of operators on your coach trip? Below you´ll find answers to your questions.

FAQs for Milan to Palermo bus

How much does a Milan Palermo coach trip cost?

This depends on, among other things, the day and travel time. The cheapest ticket for the Milan Palermo bus trip is available from £29 and takes 24h 50m. Compare offers and save money!

How much could I save by comparing buses from Milan to Palermo?

This connection is offered by 2 companies with ticket prices ranging from £29 to £78. Therefore, we suggest booking your ticket as soon as possible to ensure you’ll get the cheapest bus trip to Palermo.

How many connections are available for the Milan Palermo route on average every day?

Each day, the bus route from Milan to Palermo is offered by roughly 7 busses. By using our search, you can compare bus schedules and find your ideal trip.

How long does a bus to Palermo from Milan take?

The quickest coach from Milan to Palermo is provided by Autoservizi Salemi and takes 21h 0m. Coach tickets for this connection cost £75. However, keep in mind that the connection can take longer due to traffic.

What time is the first bus from Milan to Palermo?

The earliest bus to Palermo departs from Milan at 10:45. In this context, information about departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

What time is the last coach from Milan to Palermo?

The latest bus to Palermo departs from Milan at 18:30. Please note that departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

Which bus companies serve the Milan Palermo route?

Passengers looking to travel from Milan to Palermo can travel with FlixBus and Autoservizi Salemi. Compare all available bus tickets with our search to book the trip that works best for you.

Is there a direct bus between Milan and Palermo?

You can check all the direct connections between Milan and Palermo by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Autoservizi Salemi.

What can I take with me on the bus to Palermo from Milan?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the bus for the Milan Palermo bus route free of charge. Simply use our search to find a coach that is best suited to your needs for your planned travel date.

What equipment is available for the Milan Palermo bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make travelling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Milan to Palermo on your planned travel date.

How does CheckMyBus find the best coach deals from Milan to Palermo?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 7 daily trips between Milan and Palermo. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Milan to Palermo?

Prices and availability for 7 trips between Milan and Palermo change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Milan to Palermo

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Milan and to Palermo

Here’s an overview of the most popular bus routes to Milan and to Palermo. Simply click on the connection of your choice, and you’ll find all the details about your bus route!
Bus from Berlin to Milan Bus from Berlin to Milan
Bus from Santhià to Milan Bus from Santhià to Milan
Bus Carisio to Milan Bus Carisio to Milan
Bus to Milan from Soverato Bus to Milan from Soverato
Buses Enna to Palermo Buses Enna to Palermo
Milazzo to Palermo coach Milazzo to Palermo coach
Coach from Canicattì to Palermo Coach from Canicattì to Palermo
Coach to Palermo from Pescara Coach to Palermo from Pescara
Popular Airport Transfers to Milan and to Palermo
CheckMyBus › Coaches in Italy › Coach to Milan › Coach to Palermo

The CheckMyBus App

Free Download

App Store
CheckMyBus App
Close
GPDR CheckMyBus shield

We value your privacy!

To

show

you

the

best

bus

deals,

we

and

our

partners

use

technical,

analytical,

and

marketing

cookies

for

ads

personalisation.

We

remember

your

anonymized

details

to

provide

a

personalized

experience.