Which bus from Milan to Palermo is the cheapest?

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Which bus from Milan to Palermo is the best?

Check the bus schedule for Milan to Palermo. Here is a selection of the cheapest coach trips for the next days from bus operators like FlixBus or Autoservizi Salemi. To see the full timetable for all coaches just use or search and compare.

today
£68
tomorrow
£68
Wednesday
£56
Thursday
£53
Friday
£62
Saturday
£50
Sunday
£53

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 24h 0m 15:15 Milan Lampugnano Bus Station 15:15 Palermo Via Tommaso Fazello Bus Stop  Economy £68
Autoservizi Salemi 21h 45m 10:00 Milan Lampugnano Bus Station 07:45 Palermo Via Tommaso Fazello Bus Stop  Basic £69
Autoservizi Salemi 21h 0m 10:45 Milan San Donato Bus Station 07:45 Palermo Via Tommaso Fazello Bus Stop  Basic £69
FlixBus 24h 50m 18:30 Milan San Donato Bus Station 19:20 Palermo Via Tommaso Fazello Bus Stop  Economy £71
FlixBus 21h 55m 13:05 Milan Lampugnano Bus Station 11:00 Palermo Via Tommaso Fazello Bus Stop  Economy £71
  • Did you know that if you travel from Milan to Palermo via Cormano, you can save more than £-10? You will find the corresponding connections below.
    • FlixBus
      29h 10m
      Milan
      10 km
      10:05
      Cormano
      Cusano Milanino Bus Stop
      15:15
      Palermo
      Via Tommaso Fazello Bus Stop
      0 km
      FlixBus
      Economy
      £78

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 24h 10m 15:05 Milan Lampugnano Bus Station 15:15 Palermo Via Tommaso Fazello Bus Stop  Economy £68
FlixBus 25h 35m 17:45 Milan Lampugnano Bus Station 19:20 Palermo Via Tommaso Fazello Bus Stop  Economy £68
FlixBus 24h 50m 18:30 Milan San Donato Bus Station 19:20 Palermo Via Tommaso Fazello Bus Stop  Economy £69
FlixBus 21h 55m 13:05 Milan Lampugnano Bus Station 11:00 Palermo Via Tommaso Fazello Bus Stop  Economy £71
FlixBus 26h 10m 08:50 Milan San Donato Bus Station 11:00 Palermo Via Tommaso Fazello Bus Stop  Economy £100
  • Did you know that if you travel from Milan to Palermo via Cormano, you can save more than £-7? You will find the corresponding connections below.
    • FlixBus
      29h 10m
      Milan
      10 km
      10:05
      Cormano
      Cusano Milanino Bus Stop
      15:15
      Palermo
      Via Tommaso Fazello Bus Stop
      0 km
      FlixBus
      Economy
      £75

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 22h 30m 12:30 Milan San Donato Bus Station 11:00 Palermo Via Tommaso Fazello Bus Stop  Economy £56
FlixBus 24h 50m 18:30 Milan San Donato Bus Station 19:20 Palermo Via Tommaso Fazello Bus Stop  Economy £56
FlixBus 25h 35m 17:45 Milan Lampugnano Bus Station 19:20 Palermo Via Tommaso Fazello Bus Stop  Economy £56
FlixBus 24h 0m 15:15 Milan Lampugnano Bus Station 15:15 Palermo Via Tommaso Fazello Bus Stop  Economy £62
FlixBus 26h 30m 12:45 Milan San Donato Bus Station 15:15 Palermo Via Tommaso Fazello Bus Stop  Economy £63

Cheapest bus trips Thursday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 21h 50m 17:25 Milan San Donato Bus Station 15:15 Palermo Via Tommaso Fazello Bus Stop  Economy £53
FlixBus 22h 35m 16:40 Milan Lampugnano Bus Station 15:15 Palermo Via Tommaso Fazello Bus Stop  Economy £53
FlixBus 22h 30m 12:30 Milan San Donato Bus Station 11:00 Palermo Via Tommaso Fazello Bus Stop  Economy £55
FlixBus 21h 55m 13:05 Milan Lampugnano Bus Station 11:00 Palermo Via Tommaso Fazello Bus Stop  Economy £61
FlixBus 25h 35m 17:45 Milan Lampugnano Bus Station 19:20 Palermo Via Tommaso Fazello Bus Stop  Economy £63
  • Did you know that if you travel from Milan to Palermo via Siena, you can save more than £8? You can find the corresponding connections below.
    • Itabus
      32h 40m
      0
      10:40
      Milan
      Lampugnano Bus Station
      16:20
      Siena
      Train Station
      0
      Itabus
      Premium Economy
      £9
      • Waiting Time 6h 5m
    • FlixBus
      20h 55m
      0
      22:25
      Siena
      Train Station
      19:20
      Palermo
      Via Tommaso Fazello Bus Stop
      0
      FlixBus
      Economy
      £36
    Travel time is 10h 50m longer, but you will save £8

Cheapest bus trips Friday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 22h 35m 16:40 Milan Lampugnano Bus Station 15:15 Palermo Via Tommaso Fazello Bus Stop  Economy £62
FlixBus 21h 50m 17:25 Milan San Donato Bus Station 15:15 Palermo Via Tommaso Fazello Bus Stop  Economy £63
FlixBus 24h 50m 18:30 Milan San Donato Bus Station 19:20 Palermo Via Tommaso Fazello Bus Stop  Economy £64
Autoservizi Salemi 21h 45m 10:00 Milan Lampugnano Bus Station 07:45 Palermo Via Tommaso Fazello Bus Stop  Basic £69
Autoservizi Salemi 21h 0m 10:45 Milan San Donato Bus Station 07:45 Palermo Via Tommaso Fazello Bus Stop  Basic £69
  • Did you know that if you travel from Milan to Palermo via Cormano, you can save more than £-3? You will find the corresponding connections below.
    • FlixBus
      28h 15m
      Milan
      10 km
      11:00
      Cormano
      Cusano Milanino Bus Stop
      15:15
      Palermo
      Via Tommaso Fazello Bus Stop
      0 km
      FlixBus
      Economy
      £65
  • Did you know that if you travel from Milan to Palermo via Siena, you can save more than £28? You can find the corresponding connections below.
    • FlixBus
      26h 15m
      0
      17:05
      Milan
      San Donato Bus Station
      22:20
      Siena
      Train Station
      0
      FlixBus
      Economy
      £6
      • Waiting Time 0h 5m
    • FlixBus
      20h 55m
      0
      22:25
      Siena
      Train Station
      19:20
      Palermo
      Via Tommaso Fazello Bus Stop
      0
      FlixBus
      Economy
      £28
    Travel time is 5h 15m longer, but you will save £28

Cheapest bus trips Saturday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 21h 50m 17:25 Milan San Donato Bus Station 15:15 Palermo Via Tommaso Fazello Bus Stop  Economy £50
FlixBus 22h 35m 16:40 Milan Lampugnano Bus Station 15:15 Palermo Via Tommaso Fazello Bus Stop  Economy £50
FlixBus 24h 50m 18:30 Milan San Donato Bus Station 19:20 Palermo Via Tommaso Fazello Bus Stop  Economy £52
FlixBus 25h 35m 17:45 Milan Lampugnano Bus Station 19:20 Palermo Via Tommaso Fazello Bus Stop  Economy £52
FlixBus 22h 30m 12:30 Milan San Donato Bus Station 11:00 Palermo Via Tommaso Fazello Bus Stop  Economy £55
  • Did you know that if you travel from Milan to Palermo via Siena, you can save more than £16? You can find the corresponding connections below.
    • FlixBus
      26h 15m
      0
      17:05
      Milan
      San Donato Bus Station
      22:20
      Siena
      Train Station
      0
      FlixBus
      Economy
      £6
      • Waiting Time 0h 5m
    • FlixBus
      20h 55m
      0
      22:25
      Siena
      Train Station
      19:20
      Palermo
      Via Tommaso Fazello Bus Stop
      0
      FlixBus
      Economy
      £28
    Travel time is 4h 25m longer, but you will save £16

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 22h 30m 12:30 Milan San Donato Bus Station 11:00 Palermo Via Tommaso Fazello Bus Stop  Economy £53
FlixBus 25h 35m 17:45 Milan Lampugnano Bus Station 19:20 Palermo Via Tommaso Fazello Bus Stop  Economy £56
FlixBus 24h 50m 18:30 Milan San Donato Bus Station 19:20 Palermo Via Tommaso Fazello Bus Stop  Economy £57
FlixBus 24h 0m 15:15 Milan Lampugnano Bus Station 15:15 Palermo Via Tommaso Fazello Bus Stop  Economy £57
FlixBus 21h 55m 13:05 Milan Lampugnano Bus Station 11:00 Palermo Via Tommaso Fazello Bus Stop  Economy £65
  • Did you know that if you travel from Milan to Palermo via Siena, you can save more than £19? You can find the corresponding connections below.
    • FlixBus
      26h 15m
      0
      17:05
      Milan
      San Donato Bus Station
      22:20
      Siena
      Train Station
      0
      FlixBus
      Economy
      £6
      • Waiting Time 0h 5m
    • FlixBus
      20h 55m
      0
      22:25
      Siena
      Train Station
      19:20
      Palermo
      Via Tommaso Fazello Bus Stop
      0
      FlixBus
      Economy
      £28
    Travel time is 4h 20m longer, but you will save £19

Best Price Offer: The price for the cheapest coach from Milan to Palermo is £42 on 12/05/2026. Flexible travellers save on ticket prices.


What is the best day and time to travel by bus between Milan and Palermo?

Here is the frequency of all coach connections from Milan to Palermo. See on which day of the week you have more travel options and what time you have more bus trips to choose from.
Monday is the busiest day, with more than 8 daily coaches from Milan to Palermo. Tuesday has instead the fewest connections, with only 5 daily coaches between Milan and Palermo.
The busiest time of the day is the Afternoon, with 32 coaches from Milan to Palermo, while Morning sees the fewest connections between Milan and Palermo, with 6 offers.

All facts for Milan to Palermo bus at a glance

Compare all coach operators like FlixBus and Autoservizi Salemi that travel daily 6 times by bus from Milan to Palermo in one click. Book your Milan to Palermo bus ticket starting from £42!

Cheapest Bus £42
Fastest Bus 21h 0m
Earliest Coach 09:40
Latest Coach 18:30
Daily Bus Connections 6 Ø
Distance 887.2 km
Coach Companies FlixBus and Autoservizi Salemi

What are the cheapest coach tickets from Milan to Palermo?

Every day, 6 buses from 2 coach companies leave Milan for Palermo. Check the table below to find the cheapest prices for coach tickets for this route, starting from 04/05/2026 and for the following days. Make sure get the cheapest bus ticket!

Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday
Monday 04/05
£69
Tuesday 05/05
£68
Wednesday 06/05
£56
Thursday 07/05
£53
Friday 08/05
£62
Saturday 09/05
£50
Sunday 10/05
£53
Monday 11/05
£44
Tuesday 12/05
£42
Wednesday 13/05
£47
Thursday 14/05
£51
Friday 15/05
£56
Saturday 16/05
£46
Sunday 17/05
£52
Monday 18/05
£46
Tuesday 19/05
£44
Wednesday 20/05
£51
Thursday 21/05
£53
Friday 22/05
£58
Saturday 23/05
£50
Sunday 24/05
£59
Monday 25/05
£49
Tuesday 26/05
£45
Wednesday 27/05
£48
Thursday 28/05
£56
Friday 29/05
£65
Saturday 30/05
£58
Sunday 31/05

The cheapest time to travel from Milan to Palermo

See here on which day and which time of the day you can find the cheapest bus ticket from Milan to Palermo, for the next 30 days.
With a price starting from £42, Tuesday is the cheapest day for a coach from Milan to Palermo. Friday instead is the most expensive day with prices starting from £56.
Afternoon is the cheapest day time for bus tickets from Milan to Palermo, with £50. Morning is the most expensive time of the day with prices starting from £69.

How to save money travelling from Milan to Palermo

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying higher prices for your trip? Plan your bus trips smartly. Here are a few hacks to save money on your coach journey.

Book the ticket from Milan to Palermo in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the coach from Milan to Palermo, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Milan to Palermo are also emptier.

Check for bus deals and promotions for all bus companies in this route. On CheckMyBus we show special offers directly in the coach trip on our search. Sign-up and check or deals sections and get notifications on our latest travel hacks.

All bus stations and stops in Milan and Palermo

Here is a map with all coach stations in Milan and Palermo. Compare which stop is closest to your destination to save time to find the fastest buses and connections.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Milan to Palermo? Compare all modes of transports from Milan to Palermo.

All you need to know when you travel by bus from Milan to Palermo

Check all information on comfort and services on the coaches from Milan to Palermo. Which seat classes are available or what are the amenities of operators on your coach trip? Below you´ll find answers to your questions.

FAQs for Milan to Palermo bus

How much does a Milan Palermo coach trip cost?

This depends on, among other things, the day and travel time. The cheapest ticket for the Milan Palermo bus trip is available from £42 and takes 21h 50m. Compare offers and save money!

How much could I save by comparing buses from Milan to Palermo?

This connection is offered by 2 companies with ticket prices ranging from £42 to £100. Therefore, we suggest booking your ticket as soon as possible to ensure you’ll get the cheapest bus trip to Palermo.

How many connections are available for the Milan Palermo route on average every day?

Each day, the bus route from Milan to Palermo is offered by roughly 6 busses. By using our search, you can compare bus schedules and find your ideal trip.

How long does a bus to Palermo from Milan take?

The quickest coach from Milan to Palermo is provided by Autoservizi Salemi and takes 21h 0m. Coach tickets for this connection cost £69. However, keep in mind that the connection can take longer due to traffic.

What time is the first bus from Milan to Palermo?

The earliest bus to Palermo departs from Milan at 09:40. In this context, information about departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

What time is the last coach from Milan to Palermo?

The latest bus to Palermo departs from Milan at 18:30. Please note that departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

Which bus companies serve the Milan Palermo route?

Passengers looking to travel from Milan to Palermo can travel with FlixBus and Autoservizi Salemi. Compare all available bus tickets with our search to book the trip that works best for you.

Is there a direct bus between Milan and Palermo?

You can check all the direct connections between Milan and Palermo by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Autoservizi Salemi.

What can I take with me on the bus to Palermo from Milan?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the bus for the Milan Palermo bus route free of charge. Simply use our search to find a coach that is best suited to your needs for your planned travel date.

What equipment is available for the Milan Palermo bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make travelling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Milan to Palermo on your planned travel date.

How does CheckMyBus find the best coach deals from Milan to Palermo?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 6 daily trips between Milan and Palermo. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Milan to Palermo?

Prices and availability for 6 trips between Milan and Palermo change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Milan to Palermo

Basic
Basic

Name referring to the typical seat you will find with companies that don’t distinguish between different classes.

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Milan and to Palermo

Here’s an overview of the most popular bus routes to Milan and to Palermo. Simply click on the connection of your choice, and you’ll find all the details about your bus route!
Caserta to Milan bus Caserta to Milan bus
Coach Lausanne to Milan Coach Lausanne to Milan
Coach from Salzburg to Milan Coach from Salzburg to Milan
Sanremo to Milan coach Sanremo to Milan coach
Coaches Marsala to Palermo Coaches Marsala to Palermo
Coach Messina to Palermo Coach Messina to Palermo
Bus Rome to Palermo Bus Rome to Palermo
Catanzaro to Palermo bus Catanzaro to Palermo bus
Popular Airport Transfers to Milan and to Palermo
CheckMyBus › Coaches in Italy › Coach to Milan › Coach to Palermo

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