Which bus from Milan to Palermo is the best?
Check the bus schedule for Milan to Palermo. Here is a selection of the cheapest coach trips for the next days from bus operators like FlixBus. To see the full timetable for all coaches just use or search and compare.
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 22h 30m | 12:30 | Milan | San Donato Bus Station | 11:00 | Palermo | Via Tommaso Fazello Bus Stop | Economy | £32 |
A Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 19/03/2026 12:30:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 20/03/2026 11:00:00. 50 Economy ticket for £32 per person are available. Travel duration is 22h 30m
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| FlixBus | 21h 55m | 13:05 | Milan | Lampugnano Bus Station | 11:00 | Palermo | Via Tommaso Fazello Bus Stop | Economy | £47 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 19/03/2026 13:05:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 20/03/2026 11:00:00. 50 Economy ticket for £47 per person are available. Travel duration is 21h 55m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 22h 30m | 12:30 | Milan | San Donato Bus Station | 11:00 | Palermo | Via Tommaso Fazello Bus Stop | Economy | £39 |
A Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 20/03/2026 12:30:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 21/03/2026 11:00:00. 50 Economy ticket for £39 per person are available. Travel duration is 22h 30m
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| FlixBus | 22h 25m | 15:30 | Milan | Lampugnano Bus Station | 13:55 | Palermo | Via Tommaso Fazello Bus Stop | Economy | £42 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 20/03/2026 15:30:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 21/03/2026 13:55:00. 50 Economy ticket for £42 per person are available. Travel duration is 22h 25m
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| FlixBus | 23h 10m | 14:45 | Milan | San Donato Bus Station | 13:55 | Palermo | Via Tommaso Fazello Bus Stop | Economy | £60 |
A Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 20/03/2026 14:45:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 21/03/2026 13:55:00. 50 Economy ticket for £60 per person are available. Travel duration is 23h 10m
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| FlixBus | 21h 55m | 13:05 | Milan | Lampugnano Bus Station | 11:00 | Palermo | Via Tommaso Fazello Bus Stop | Economy | £60 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 20/03/2026 13:05:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 21/03/2026 11:00:00. 50 Economy ticket for £60 per person are available. Travel duration is 21h 55m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 22h 30m | 12:30 | Milan | San Donato Bus Station | 11:00 | Palermo | Via Tommaso Fazello Bus Stop | Economy | £38 |
A Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 21/03/2026 12:30:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 22/03/2026 11:00:00. 50 Economy ticket for £38 per person are available. Travel duration is 22h 30m
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| FlixBus | 22h 25m | 15:30 | Milan | Lampugnano Bus Station | 13:55 | Palermo | Via Tommaso Fazello Bus Stop | Economy | £59 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 21/03/2026 15:30:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 22/03/2026 13:55:00. 50 Economy ticket for £59 per person are available. Travel duration is 22h 25m
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| FlixBus | 21h 55m | 13:05 | Milan | Lampugnano Bus Station | 11:00 | Palermo | Via Tommaso Fazello Bus Stop | Economy | £63 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 21/03/2026 13:05:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 22/03/2026 11:00:00. 50 Economy ticket for £63 per person are available. Travel duration is 21h 55m
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| FlixBus | 23h 10m | 14:45 | Milan | San Donato Bus Station | 13:55 | Palermo | Via Tommaso Fazello Bus Stop | Economy | £67 |
A Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 21/03/2026 14:45:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 22/03/2026 13:55:00. 50 Economy ticket for £67 per person are available. Travel duration is 23h 10m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 22h 30m | 12:30 | Milan | San Donato Bus Station | 11:00 | Palermo | Via Tommaso Fazello Bus Stop | Economy | £55 |
A Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 22/03/2026 12:30:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 23/03/2026 11:00:00. 50 Economy ticket for £55 per person are available. Travel duration is 22h 30m
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| FlixBus | 22h 25m | 15:30 | Milan | Lampugnano Bus Station | 13:55 | Palermo | Via Tommaso Fazello Bus Stop | Economy | £66 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 22/03/2026 15:30:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 23/03/2026 13:55:00. 50 Economy ticket for £66 per person are available. Travel duration is 22h 25m
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| FlixBus | 21h 55m | 13:05 | Milan | Lampugnano Bus Station | 11:00 | Palermo | Via Tommaso Fazello Bus Stop | Economy | £73 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 22/03/2026 13:05:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 23/03/2026 11:00:00. 50 Economy ticket for £73 per person are available. Travel duration is 21h 55m
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| FlixBus | 23h 10m | 14:45 | Milan | San Donato Bus Station | 13:55 | Palermo | Via Tommaso Fazello Bus Stop | Economy | £78 |
A Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 22/03/2026 14:45:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 23/03/2026 13:55:00. 50 Economy ticket for £78 per person are available. Travel duration is 23h 10m
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FlixBusSave more than 20%25h 55mMilan8 km09:05AssagoMilanofiori Forum11:00PalermoVia Tommaso Fazello Bus Stop0 kmEconomyA Bus from FlixBus goes from Milanofiori Forum, Assago (Italy) at 22/03/2026 09:05:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 23/03/2026 11:00:00. 50 Economy ticket for £44 per person are available. Travel duration is 25h 55m
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FlixBus26h 15m012:00MilanLampugnano Bus Station19:00LuccaCentral Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 23/03/2026 12:00:00 to Central Station, Lucca (Italy) arriving at 23/03/2026 19:00:00. 50 Economy ticket for £16 per person are available. Travel duration is 7h 0m
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FlixBus19h 10m019:05LuccaCentral Station14:15PalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Lucca (Italy) at 23/03/2026 19:05:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 24/03/2026 14:15:00. 50 Economy ticket for £20 per person are available. Travel duration is 19h 10m
Waiting Time 0h 5m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 22h 25m | 15:30 | Milan | Lampugnano Bus Station | 13:55 | Palermo | Via Tommaso Fazello Bus Stop | Economy | £29 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 23/03/2026 15:30:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 24/03/2026 13:55:00. 50 Economy ticket for £29 per person are available. Travel duration is 22h 25m
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| FlixBus | 25h 20m | 09:40 | Milan | San Donato Bus Station | 11:00 | Palermo | Via Tommaso Fazello Bus Stop | Economy | £37 |
A Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 23/03/2026 09:40:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 24/03/2026 11:00:00. 50 Economy ticket for £37 per person are available. Travel duration is 25h 20m
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| FlixBus | 23h 10m | 14:45 | Milan | San Donato Bus Station | 13:55 | Palermo | Via Tommaso Fazello Bus Stop | Economy | £37 |
A Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 23/03/2026 14:45:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 24/03/2026 13:55:00. 50 Economy ticket for £37 per person are available. Travel duration is 23h 10m
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| FlixBus | 21h 55m | 13:05 | Milan | Lampugnano Bus Station | 11:00 | Palermo | Via Tommaso Fazello Bus Stop | Economy | £54 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 23/03/2026 13:05:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 24/03/2026 11:00:00. 50 Economy ticket for £54 per person are available. Travel duration is 21h 55m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 25h 55m | 12:00 | Milan | San Donato Bus Station | 13:55 | Palermo | Via Tommaso Fazello Bus Stop | Economy | £37 |
A Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 24/03/2026 12:00:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 25/03/2026 13:55:00. 50 Economy ticket for £37 per person are available. Travel duration is 25h 55m
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| FlixBus | 22h 25m | 15:30 | Milan | Lampugnano Bus Station | 13:55 | Palermo | Via Tommaso Fazello Bus Stop | Economy | £37 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 24/03/2026 15:30:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 25/03/2026 13:55:00. 50 Economy ticket for £37 per person are available. Travel duration is 22h 25m
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| FlixBus | 26h 10m | 08:50 | Milan | San Donato Bus Station | 11:00 | Palermo | Via Tommaso Fazello Bus Stop | Economy | £42 |
A Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 24/03/2026 08:50:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 25/03/2026 11:00:00. 50 Economy ticket for £42 per person are available. Travel duration is 26h 10m
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| FlixBus | 21h 55m | 13:05 | Milan | Lampugnano Bus Station | 11:00 | Palermo | Via Tommaso Fazello Bus Stop | Economy | £65 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 24/03/2026 13:05:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 25/03/2026 11:00:00. 50 Economy ticket for £65 per person are available. Travel duration is 21h 55m
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Best Price Offer: The price for the cheapest coach from Milan to Palermo is £29 on 23/03/2026. Flexible travellers save on ticket prices.
What is the best day and time to travel by bus between Milan and Palermo?
All facts for Milan to Palermo bus at a glance
Compare all coach operators like FlixBus that travel daily 3 times by bus from Milan to Palermo in one click. Book your Milan to Palermo bus ticket starting from £29!
| Cheapest Bus | £29 |
| Fastest Bus | 21h 55m |
| Earliest Coach | 12:30 |
| Latest Coach | 15:30 |
| Daily Bus Connections | 3 Ø |
| Distance | 887.2 km |
| Coach Companies | FlixBus |
What are the cheapest coach tickets from Milan to Palermo?
Every day, 3 buses from 1 coach companies leave Milan for Palermo. Check the table below to find the cheapest prices for coach tickets for this route, starting from 18/03/2026 and for the following days. Make sure get the cheapest bus ticket!
The cheapest time to travel from Milan to Palermo
How to save money travelling from Milan to Palermo
Book the ticket from Milan to Palermo in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the coach from Milan to Palermo, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Milan to Palermo are also emptier.Check for bus deals and promotions for all bus companies in this route. On CheckMyBus we show special offers directly in the coach trip on our search. Sign-up and check or deals sections and get notifications on our latest travel hacks.
All bus stations and stops in Milan and Palermo
Here is a map with all coach stations in Milan and Palermo. Compare which stop is closest to your destination to save time to find the fastest buses and connections.
Compare the bus with other modes of transport
All you need to know when you travel by bus from Milan to Palermo
FAQs for Milan to Palermo bus
How much does a Milan Palermo coach trip cost?
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How many connections are available for the Milan Palermo route on average every day?
How long does a bus to Palermo from Milan take?
What time is the first bus from Milan to Palermo?
What time is the last coach from Milan to Palermo?
Which bus companies serve the Milan Palermo route?
Is there a direct bus between Milan and Palermo?
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What equipment is available for the Milan Palermo bus route?
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Available seat classes which are offered on the bus route Milan to Palermo
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
More bus routes to Milan and to Palermo
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