Bus and Coach from Rome to Palermo: Compare all prices

Compare all timetables for the bus from Rome to Palermo

Here is a selection of the cheapest bus trips from the schedule from Rome to Palermo from various bus operators like FlixBus, Itabus or Autoservizi Salemi for the next days.

today

£34

tomorrow

£36

Wednesday

£33

Thursday

£35

Friday

£36

Saturday

£39

Sunday

£38

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Itabus	13h 35m	18:15	Rome	Tiburtina Bus Station	07:50	Palermo	Via Fazello	Premium Economy	£34	A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 03/08/2026 18:15:00 to Via Fazello, Palermo (Italy) arriving at 04/08/2026 07:50:00. 50 Premium Economy ticket for £34 per person are available. Travel duration is 13h 35m
Autoservizi Salemi	11h 45m	20:00	Rome	Tiburtina Bus Station	07:45	Palermo	Via Tommaso Fazello Bus Stop	Economy	£49	A Bus from Autoservizi Salemi goes from Tiburtina Bus Station, Rome (Italy) at 03/08/2026 20:00:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 04/08/2026 07:45:00. 50 Economy ticket for £49 per person are available. Travel duration is 11h 45m
FlixBus	15h 45m	23:30	Rome	Tiburtina Bus Station	15:15	Palermo	Via Tommaso Fazello Bus Stop	Economy	£83	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 03/08/2026 23:30:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 04/08/2026 15:15:00. 50 Economy ticket for £83 per person are available. Travel duration is 15h 45m
FlixBus	18h 45m	16:30	Rome	Tiburtina Bus Station	11:15	Palermo	Via Tommaso Fazello Bus Stop	Economy	£87	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 03/08/2026 16:30:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 04/08/2026 11:15:00. 50 Economy ticket for £87 per person are available. Travel duration is 18h 45m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	13h 55m	01:20	Rome	Tiburtina Bus Station	15:15	Palermo	Via Tommaso Fazello Bus Stop	Economy	£36	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 04/08/2026 01:20:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 04/08/2026 15:15:00. 50 Economy ticket for £36 per person are available. Travel duration is 13h 55m
Autoservizi Salemi	11h 45m	20:00	Rome	Tiburtina Bus Station	07:45	Palermo	Via Tommaso Fazello Bus Stop	Economy	£56	A Bus from Autoservizi Salemi goes from Tiburtina Bus Station, Rome (Italy) at 04/08/2026 20:00:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 05/08/2026 07:45:00. 50 Economy ticket for £56 per person are available. Travel duration is 11h 45m
FlixBus	15h 45m	23:30	Rome	Tiburtina Bus Station	15:15	Palermo	Via Tommaso Fazello Bus Stop	Economy	£76	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 04/08/2026 23:30:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 05/08/2026 15:15:00. 50 Economy ticket for £76 per person are available. Travel duration is 15h 45m
FlixBus	14h 0m	21:00	Rome	Tiburtina Bus Station	11:00	Palermo	Via Tommaso Fazello Bus Stop	Economy	£82	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 04/08/2026 21:00:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 05/08/2026 11:00:00. 50 Economy ticket for £82 per person are available. Travel duration is 14h 0m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	13h 55m	01:20	Rome	Tiburtina Bus Station	15:15	Palermo	Via Tommaso Fazello Bus Stop	Economy	£33	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 05/08/2026 01:20:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 05/08/2026 15:15:00. 50 Economy ticket for £33 per person are available. Travel duration is 13h 55m
Autoservizi Salemi	11h 45m	20:00	Rome	Tiburtina Bus Station	07:45	Palermo	Via Tommaso Fazello Bus Stop	Economy	£56	A Bus from Autoservizi Salemi goes from Tiburtina Bus Station, Rome (Italy) at 05/08/2026 20:00:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 06/08/2026 07:45:00. 50 Economy ticket for £56 per person are available. Travel duration is 11h 45m
FlixBus	19h 40m	23:45	Rome	Tiburtina Bus Station	19:25	Palermo	Via Tommaso Fazello Bus Stop	Economy	£71	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 05/08/2026 23:45:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 06/08/2026 19:25:00. 50 Economy ticket for £71 per person are available. Travel duration is 19h 40m
FlixBus	18h 45m	16:30	Rome	Tiburtina Bus Station	11:15	Palermo	Via Tommaso Fazello Bus Stop	Economy	£76	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 05/08/2026 16:30:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 06/08/2026 11:15:00. 50 Economy ticket for £76 per person are available. Travel duration is 18h 45m

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Itabus	13h 35m	18:15	Rome	Tiburtina Coach Station	07:50	Palermo	Via Tommaso Fazello Bus Stop	Economy	£35	A Bus from Itabus goes from Tiburtina Coach Station, Rome (Italy) at 06/08/2026 18:15:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 07/08/2026 07:50:00. 50 Economy ticket for £35 per person are available. Travel duration is 13h 35m
FlixBus	13h 55m	01:20	Rome	Tiburtina Bus Station	15:15	Palermo	Via Tommaso Fazello Bus Stop	Economy	£48	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 06/08/2026 01:20:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 06/08/2026 15:15:00. 50 Economy ticket for £48 per person are available. Travel duration is 13h 55m
Autoservizi Salemi	11h 45m	20:00	Rome	Tiburtina Bus Station	07:45	Palermo	Via Tommaso Fazello Bus Stop	Economy	£49	A Bus from Autoservizi Salemi goes from Tiburtina Bus Station, Rome (Italy) at 06/08/2026 20:00:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 07/08/2026 07:45:00. 50 Economy ticket for £49 per person are available. Travel duration is 11h 45m
FlixBus	19h 40m	23:45	Rome	Tiburtina Bus Station	19:25	Palermo	Via Tommaso Fazello Bus Stop	Economy	£74	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 06/08/2026 23:45:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 07/08/2026 19:25:00. 50 Economy ticket for £74 per person are available. Travel duration is 19h 40m

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	13h 55m	01:20	Rome	Tiburtina Bus Station	15:15	Palermo	Via Tommaso Fazello Bus Stop	Economy	£36	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 07/08/2026 01:20:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 07/08/2026 15:15:00. 50 Economy ticket for £36 per person are available. Travel duration is 13h 55m
Itabus	13h 35m	18:15	Rome	Tiburtina Bus Station	07:50	Palermo	Piazza Cairoli Bus Station	Economy	£39	A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 07/08/2026 18:15:00 to Piazza Cairoli Bus Station, Palermo (Italy) arriving at 08/08/2026 07:50:00. 50 Economy ticket for £39 per person are available. Travel duration is 13h 35m
Autoservizi Salemi	11h 45m	20:00	Rome	Tiburtina Bus Station	07:45	Palermo	Via Tommaso Fazello Bus Stop	Economy	£53	A Bus from Autoservizi Salemi goes from Tiburtina Bus Station, Rome (Italy) at 07/08/2026 20:00:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 08/08/2026 07:45:00. 50 Economy ticket for £53 per person are available. Travel duration is 11h 45m
FlixBus	18h 45m	16:30	Rome	Tiburtina Bus Station	11:15	Palermo	Via Tommaso Fazello Bus Stop	Economy	£85	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 07/08/2026 16:30:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 08/08/2026 11:15:00. 50 Economy ticket for £85 per person are available. Travel duration is 18h 45m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Itabus	13h 35m	18:15	Rome	Tiburtina Bus Station	07:50	Palermo	Piazza Cairoli Bus Station	Economy	£39	A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 08/08/2026 18:15:00 to Piazza Cairoli Bus Station, Palermo (Italy) arriving at 09/08/2026 07:50:00. 50 Economy ticket for £39 per person are available. Travel duration is 13h 35m
FlixBus	13h 55m	01:20	Rome	Tiburtina Bus Station	15:15	Palermo	Via Tommaso Fazello Bus Stop	Economy	£50	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 08/08/2026 01:20:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 08/08/2026 15:15:00. 50 Economy ticket for £50 per person are available. Travel duration is 13h 55m
Autoservizi Salemi	11h 45m	20:00	Rome	Tiburtina Bus Station	07:45	Palermo	Via Tommaso Fazello Bus Stop	Economy	£53	A Bus from Autoservizi Salemi goes from Tiburtina Bus Station, Rome (Italy) at 08/08/2026 20:00:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 09/08/2026 07:45:00. 50 Economy ticket for £53 per person are available. Travel duration is 11h 45m
FlixBus	19h 40m	23:45	Rome	Tiburtina Bus Station	19:25	Palermo	Via Tommaso Fazello Bus Stop	Economy	£80	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 08/08/2026 23:45:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 09/08/2026 19:25:00. 50 Economy ticket for £80 per person are available. Travel duration is 19h 40m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	13h 55m	01:20	Rome	Tiburtina Bus Station	15:15	Palermo	Via Tommaso Fazello Bus Stop	Economy	£38	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 09/08/2026 01:20:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 09/08/2026 15:15:00. 50 Economy ticket for £38 per person are available. Travel duration is 13h 55m
Itabus	13h 35m	18:15	Rome	Tiburtina Bus Station	07:50	Palermo	Piazza Cairoli Bus Station	Economy	£39	A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 09/08/2026 18:15:00 to Piazza Cairoli Bus Station, Palermo (Italy) arriving at 10/08/2026 07:50:00. 50 Economy ticket for £39 per person are available. Travel duration is 13h 35m
Autoservizi Salemi	11h 45m	20:00	Rome	Tiburtina Bus Station	07:45	Palermo	Via Tommaso Fazello Bus Stop	Economy	£49	A Bus from Autoservizi Salemi goes from Tiburtina Bus Station, Rome (Italy) at 09/08/2026 20:00:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 10/08/2026 07:45:00. 50 Economy ticket for £49 per person are available. Travel duration is 11h 45m
FlixBus	19h 15m	15:45	Rome	Tiburtina Bus Station	11:00	Palermo	Via Tommaso Fazello Bus Stop	Economy	£84	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 09/08/2026 15:45:00 to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 10/08/2026 11:00:00. 50 Economy ticket for £84 per person are available. Travel duration is 19h 15m

Best Price Offer: The price for the cheapest coach from Rome to Palermo is £23 on 29/08/2026. Flexible travellers save on ticket prices.

Frequency of bus connections between Rome and Palermo

See here how frequent the connections between Rome and Palermo are, during different times and days of the week.

Saturday is the busiest day, with more than 15 daily coaches from Rome to Palermo. Tuesday has instead the fewest connections, with only 7 daily coaches between Rome and Palermo.

The busiest time of the day is the Evening, with 65 coaches from Rome to Palermo, while Night sees the fewest connections between Rome and Palermo, with 6 offers.

Facts about coaches from Rome to Palermo

Compare all providers like FlixBus, Itabus and Autoservizi Salemi that travel 11 times every day by bus from Rome to Palermo in one click! Book your bus ticket from Rome to Palermo starting from £23!

Cheapest Bus	£23
Fastest Bus	11h 45m
Earliest Coach	16:30
Latest Coach	23:45
Daily Bus Connections	11 Ø
Distance	427.4 km
Coach Companies	FlixBus, Itabus and Autoservizi Salemi

Cheapest coach connections from Rome to Palermo

Every day, 11 buses from 3 coach companies leave Rome for Palermo: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 03/08/2026 and for the following days.

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday

Monday 03/08

£83

Tuesday 04/08

£36

Wednesday 05/08

£33

Thursday 06/08

£39

Friday 07/08

£35

Saturday 08/08

£50

Sunday 09/08

£35

Monday 10/08

£46

Tuesday 11/08

£36

Wednesday 12/08

£33

Thursday 13/08

£41

Friday 14/08

£41

Saturday 15/08

£26

Sunday 16/08

£59

Monday 17/08

£26

Tuesday 18/08

£65

Wednesday 19/08

£29

Thursday 20/08

£26

Friday 21/08

£24

Saturday 22/08

£28

Sunday 23/08

£24

Monday 24/08

£26

Tuesday 25/08

£27

Wednesday 26/08

£24

Thursday 27/08

£39

Friday 28/08

£29

Saturday 29/08

£23

Sunday 30/08

The cheapest time to travel from Rome to Palermo

See here on which day and which time of the day you can find the cheapest bus ticket from Rome to Palermo, for the next 30 days.

With a price starting from £23, Saturday is the cheapest day for a coach from Rome to Palermo. Tuesday instead is the most expensive day with prices starting from £27.

Night is the cheapest day time for bus tickets from Rome to Palermo, with £23. Afternoon is the most expensive time of the day with prices starting from £76.

How to save money travelling from Rome to Palermo

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Rome to Palermo in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Rome to Palermo, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Rome to Palermo are also emptier.

Beloved bus companies from Rome to Palermo

These are the most booked bus companies between Rome to Palermo from our users.

Autoservizi Salemi from Rome to Palermo

Here you will find the key facts about the Autoservizi Salemi bus route Rome to Palermo:

Cheapest Price	£49
Fastest Coach	11h 45m
Earliest Coach	20:00
Last Coach	20:00
Daily Connections	2 Ø
Found on	03/08/2026

All bus stations and stops in Rome and Palermo

The map below shows you where to find all the bus stations in Rome and Palermo.

Anagnina Bus Station

Piazzale della Stazione Anagnina

Termini Bus Station

Piazza dei Cinquecento 64

Tiburtina Bus Station

Largo Guido Mazzoni 4

Tiburtina Coach Station

Tiburtina Partenze

Vatican City

Via Crescenzio 19

Oreto Orsi Bus Stop

Via Oreto 389

Piazza Cairoli Bus Station

Piazza Cairoli Piazza Cairoli

Piazza Indipendenza Station

Piazza Indipendenza Palazzo Reale

Via Tommaso Fazello Bus Stop

Via Tommaso Fazello

Via della Libertà

Via della Libertà 163

Service and Comfort on the bus from Rome to Palermo

Want to know which seat classes are available on the coaches from Rome to Palermo? Or which bus companies serve the route Rome to Palermo? Below you will find answers to your questions.

FAQs about the Rome to Palermo bus

How much does a Rome - Palermo coach trip cost?

This depends on, among other things, the day and travel time. The cheapest ticket for the Rome - Palermo bus trip is available from £23 and takes 13h 55m. Compare offers and save money!

How much could I save by comparing buses from Rome to Palermo?

The connection Rome to Palermo is offered by 3 companies with ticket prices ranging from £23 to £144. Therefore, we suggest booking your ticket as soon as possible to ensure you will get the cheapest ticket price.

How many connections are available for the Rome - Palermo route on average every day?

Each day, the bus route from Rome to Palermo is offered by roughly 11 busses. By using our search, you can compare bus schedules and find your ideal trip.

How long does a bus to Palermo from Rome take?

The quickest coach from Rome to Palermo is provided by Autoservizi Salemi and takes 11h 45m. Coach tickets for this connection cost £55. However, keep in mind that the connection can take longer due to traffic.

What time is the first bus from Rome to Palermo?

The earliest bus to Palermo departs from Rome at 16:30. In this context, information about departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

What time is the last coach from Rome to Palermo?

The latest bus to Palermo departs from Rome at 23:45. Please note that departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

Which bus companies serve the Rome - Palermo route?

Passengers looking to travel from Rome to Palermo can travel with FlixBus, Itabus and Autoservizi Salemi. Compare all available bus tickets with our search to book the trip that works best for you.

Is there a direct bus between Rome and Palermo?

You can check all the direct connections between Rome and Palermo by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus, Itabus and Autoservizi Salemi.

What can I take with me on the bus to Palermo from Rome?

Depending on which provider you travel with, what you are allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the bus for the Rome Palermo bus route free of charge. Simply use our search to find a coach that is best suited to your needs for your planned travel date.

What equipment is available for the Rome Palermo bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make travelling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Rome to Palermo on your planned travel date.

How does CheckMyBus find the best bus deals from Rome to Palermo?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 11 daily trips between Rome and Palermo. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Rome to Palermo?

Prices and availability for 11 trips between Rome and Palermo change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Rome to Palermo

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

Premium Economy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

More bus routes to Rome and to Palermo

Here’s an overview of the most popular bus routes to Rome and to Palermo. Simply click on the connection of your choice, and you will find all the details about your bus route!