Which bus from Madrid to Santander is the best?
Check the bus schedule for Madrid to Santander. Here is a selection of the cheapest coach trips for the next days from bus operators like ALSA or FlixBus. To see the full timetable for all coaches just use or search and compare.
Cheapest bus trips today
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ALSA5h 50m008:00MadridAvenida de América Coach Station13:50SantanderCoach Station0EconomyA Bus from ALSA goes from Avenida de América Coach Station, Madrid (Spain) at 22/06/2025 08:00:00 to Coach Station, Santander (Spain) arriving at 22/06/2025 13:50:00. 50 Economy ticket for £31 per person are available. Travel duration is 5h 50m
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ALSA5h 30m018:30MadridAvenida de América Coach Station00:00SantanderCoach Station0EconomyA Bus from ALSA goes from Avenida de América Coach Station, Madrid (Spain) at 22/06/2025 18:30:00 to Coach Station, Santander (Spain) arriving at 23/06/2025 00:00:00. 50 Economy ticket for £31 per person are available. Travel duration is 5h 30m
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ALSA5h 45m010:30MadridAvenida de América Coach Station16:15SantanderCoach Station0EconomyA Bus from ALSA goes from Avenida de América Coach Station, Madrid (Spain) at 22/06/2025 10:30:00 to Coach Station, Santander (Spain) arriving at 22/06/2025 16:15:00. 50 Economy ticket for £34 per person are available. Travel duration is 5h 45m
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ALSA5h 45m016:30MadridAvenida de América Coach Station22:15SantanderCoach Station0EconomyA Bus from ALSA goes from Avenida de América Coach Station, Madrid (Spain) at 22/06/2025 16:30:00 to Coach Station, Santander (Spain) arriving at 22/06/2025 22:15:00. 50 Economy ticket for £34 per person are available. Travel duration is 5h 45m
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ALSA5h 30m023:30MadridAvenida de América Coach Station05:00SantanderCoach Station0EconomyA Bus from ALSA goes from Avenida de América Coach Station, Madrid (Spain) at 22/06/2025 23:30:00 to Coach Station, Santander (Spain) arriving at 23/06/2025 05:00:00. 50 Economy ticket for £34 per person are available. Travel duration is 5h 30m
Cheapest bus trips tomorrow
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ALSA5h 50m008:00MadridAvenida de Aragon13:50SantanderCoach Station0EconomyA Bus from ALSA goes from Avenida de Aragon, Madrid (Spain) at 23/06/2025 08:00:00 to Coach Station, Santander (Spain) arriving at 23/06/2025 13:50:00. 50 Economy ticket for £23 per person are available. Travel duration is 5h 50m
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ALSA5h 45m010:30MadridAvenida de Aragon16:15SantanderCoach Station0EconomyA Bus from ALSA goes from Avenida de Aragon, Madrid (Spain) at 23/06/2025 10:30:00 to Coach Station, Santander (Spain) arriving at 23/06/2025 16:15:00. 50 Economy ticket for £23 per person are available. Travel duration is 5h 45m
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ALSA5h 45m016:30MadridAvenida de Aragon22:15SantanderCoach Station0EconomyA Bus from ALSA goes from Avenida de Aragon, Madrid (Spain) at 23/06/2025 16:30:00 to Coach Station, Santander (Spain) arriving at 23/06/2025 22:15:00. 50 Economy ticket for £23 per person are available. Travel duration is 5h 45m
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FlixBus16h 40m016:40MadridSur Bus Station09:20SantanderCoach Station0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 23/06/2025 16:40:00 to Coach Station, Santander (Spain) arriving at 24/06/2025 09:20:00. 50 Economy ticket for £59 per person are available. Travel duration is 16h 40m
Cheapest bus trips Tuesday
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ALSA5h 50m008:00MadridAvenida de América Coach Station13:50SantanderCoach Station0EconomyA Bus from ALSA goes from Avenida de América Coach Station, Madrid (Spain) at 24/06/2025 08:00:00 to Coach Station, Santander (Spain) arriving at 24/06/2025 13:50:00. 50 Economy ticket for £31 per person are available. Travel duration is 5h 50m
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ALSA5h 45m010:30MadridAvenida de América Coach Station16:15SantanderCoach Station0EconomyA Bus from ALSA goes from Avenida de América Coach Station, Madrid (Spain) at 24/06/2025 10:30:00 to Coach Station, Santander (Spain) arriving at 24/06/2025 16:15:00. 50 Economy ticket for £31 per person are available. Travel duration is 5h 45m
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ALSA5h 30m013:00MadridAvenida de América Coach Station18:30SantanderCoach Station0EconomyA Bus from ALSA goes from Avenida de América Coach Station, Madrid (Spain) at 24/06/2025 13:00:00 to Coach Station, Santander (Spain) arriving at 24/06/2025 18:30:00. 50 Economy ticket for £34 per person are available. Travel duration is 5h 30m
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FlixBus16h 40m016:40MadridSur Bus Station09:20SantanderCoach Station0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 24/06/2025 16:40:00 to Coach Station, Santander (Spain) arriving at 25/06/2025 09:20:00. 50 Economy ticket for £53 per person are available. Travel duration is 16h 40m
Cheapest bus trips Wednesday
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ALSA5h 50m008:00MadridAvenida de América Coach Station13:50SantanderCoach Station0EconomyA Bus from ALSA goes from Avenida de América Coach Station, Madrid (Spain) at 25/06/2025 08:00:00 to Coach Station, Santander (Spain) arriving at 25/06/2025 13:50:00. 50 Economy ticket for £31 per person are available. Travel duration is 5h 50m
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ALSA5h 45m010:30MadridAvenida de América Coach Station16:15SantanderCoach Station0EconomyA Bus from ALSA goes from Avenida de América Coach Station, Madrid (Spain) at 25/06/2025 10:30:00 to Coach Station, Santander (Spain) arriving at 25/06/2025 16:15:00. 50 Economy ticket for £31 per person are available. Travel duration is 5h 45m
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ALSA5h 50m008:00MadridAvenida de Aragon13:50SantanderCoach Station0EconomyA Bus from ALSA goes from Avenida de Aragon, Madrid (Spain) at 25/06/2025 08:00:00 to Coach Station, Santander (Spain) arriving at 25/06/2025 13:50:00. 50 Economy ticket for £34 per person are available. Travel duration is 5h 50m
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ALSA5h 45m010:30MadridAvenida de Aragon16:15SantanderCoach Station0EconomyA Bus from ALSA goes from Avenida de Aragon, Madrid (Spain) at 25/06/2025 10:30:00 to Coach Station, Santander (Spain) arriving at 25/06/2025 16:15:00. 50 Economy ticket for £34 per person are available. Travel duration is 5h 45m
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ALSA5h 30m013:00MadridAvenida de América Coach Station18:30SantanderCoach Station0EconomyA Bus from ALSA goes from Avenida de América Coach Station, Madrid (Spain) at 25/06/2025 13:00:00 to Coach Station, Santander (Spain) arriving at 25/06/2025 18:30:00. 50 Economy ticket for £34 per person are available. Travel duration is 5h 30m
Cheapest bus trips Thursday
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ALSA8h 0m013:15MadridIntercambiador de Moncloa21:15SantanderCoach Station0EconomyA Bus from ALSA goes from Intercambiador de Moncloa, Madrid (Spain) at 26/06/2025 13:15:00 to Coach Station, Santander (Spain) arriving at 26/06/2025 21:15:00. 50 Economy ticket for £30 per person are available. Travel duration is 8h 0m
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ALSA5h 50m008:00MadridAvenida de América Coach Station13:50SantanderCoach Station0EconomyA Bus from ALSA goes from Avenida de América Coach Station, Madrid (Spain) at 26/06/2025 08:00:00 to Coach Station, Santander (Spain) arriving at 26/06/2025 13:50:00. 50 Economy ticket for £31 per person are available. Travel duration is 5h 50m
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ALSA5h 45m010:30MadridAvenida de América Coach Station16:15SantanderCoach Station0EconomyA Bus from ALSA goes from Avenida de América Coach Station, Madrid (Spain) at 26/06/2025 10:30:00 to Coach Station, Santander (Spain) arriving at 26/06/2025 16:15:00. 50 Economy ticket for £31 per person are available. Travel duration is 5h 45m
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FlixBus16h 40m016:40MadridSur Bus Station09:20SantanderCoach Station0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 26/06/2025 16:40:00 to Coach Station, Santander (Spain) arriving at 27/06/2025 09:20:00. 50 Economy ticket for £51 per person are available. Travel duration is 16h 40m
Cheapest bus trips Friday
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ALSA8h 0m013:15MadridIntercambiador de Moncloa21:15SantanderCoach Station0EconomyA Bus from ALSA goes from Intercambiador de Moncloa, Madrid (Spain) at 27/06/2025 13:15:00 to Coach Station, Santander (Spain) arriving at 27/06/2025 21:15:00. 50 Economy ticket for £30 per person are available. Travel duration is 8h 0m
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ALSA5h 50m008:00MadridAvenida de América Coach Station13:50SantanderCoach Station0EconomyA Bus from ALSA goes from Avenida de América Coach Station, Madrid (Spain) at 27/06/2025 08:00:00 to Coach Station, Santander (Spain) arriving at 27/06/2025 13:50:00. 50 Economy ticket for £33 per person are available. Travel duration is 5h 50m
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ALSA5h 45m010:30MadridAvenida de América Coach Station16:15SantanderCoach Station0EconomyA Bus from ALSA goes from Avenida de América Coach Station, Madrid (Spain) at 27/06/2025 10:30:00 to Coach Station, Santander (Spain) arriving at 27/06/2025 16:15:00. 50 Economy ticket for £34 per person are available. Travel duration is 5h 45m
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FlixBus16h 40m016:40MadridSur Bus Station09:20SantanderCoach Station0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 27/06/2025 16:40:00 to Coach Station, Santander (Spain) arriving at 28/06/2025 09:20:00. 50 Economy ticket for £61 per person are available. Travel duration is 16h 40m
Cheapest bus trips Saturday
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ALSA8h 0m013:15MadridIntercambiador de Moncloa21:15SantanderCoach Station0EconomyA Bus from ALSA goes from Intercambiador de Moncloa, Madrid (Spain) at 28/06/2025 13:15:00 to Coach Station, Santander (Spain) arriving at 28/06/2025 21:15:00. 50 Economy ticket for £30 per person are available. Travel duration is 8h 0m
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ALSA5h 45m010:30MadridAvenida de América Coach Station16:15SantanderCoach Station0EconomyA Bus from ALSA goes from Avenida de América Coach Station, Madrid (Spain) at 28/06/2025 10:30:00 to Coach Station, Santander (Spain) arriving at 28/06/2025 16:15:00. 50 Economy ticket for £31 per person are available. Travel duration is 5h 45m
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ALSA5h 45m016:30MadridAvenida de América Coach Station22:15SantanderCoach Station0EconomyA Bus from ALSA goes from Avenida de América Coach Station, Madrid (Spain) at 28/06/2025 16:30:00 to Coach Station, Santander (Spain) arriving at 28/06/2025 22:15:00. 50 Economy ticket for £31 per person are available. Travel duration is 5h 45m
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FlixBus16h 40m016:40MadridSur Bus Station09:20SantanderCoach Station0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 28/06/2025 16:40:00 to Coach Station, Santander (Spain) arriving at 29/06/2025 09:20:00. 50 Economy ticket for £62 per person are available. Travel duration is 16h 40m
What is the best day and time to travel by bus between Madrid and Santander?
All facts for Madrid to Santander bus at a glance
Compare all coach operators like ALSA and FlixBus that travel daily 18 times by bus from Madrid to Santander in one click. Book your Madrid to Santander bus ticket starting from £23!
Cheapest Bus | £23 |
Fastest Bus | 5h 30m |
Earliest Coach | 00:30 |
Latest Coach | 18:30 |
Daily Bus Connections | 18 Ø |
Distance | 338.8 km |
Coach Companies | ALSA and FlixBus |
What are the cheapest coach tickets from Madrid to Santander?
Every day, 18 buses from 2 coach companies leave Madrid for Santander. Check the table below to find the cheapest prices for coach tickets for this route, starting from 23/06/2025 and for the following days. Make sure get the cheapest bus ticket!
The cheapest time to travel from Madrid to Santander
How to save money travelling from Madrid to Santander
Book the ticket from Madrid to Santander in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the coach from Madrid to Santander, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Madrid to Santander are also emptier.Check for bus deals and promotions for all bus companies in this route. On CheckMyBus we show special offers directly in the coach trip on our search. Sign-up and check or deals sections and get notifications on our latest travel hacks.
All bus stations and stops in Madrid and Santander
Here is a map with all coach stations in Madrid and Santander. Compare which stop is closest to your destination to save time to find the fastest buses and connections.
Compare the bus with other modes of transport
All you need to know when you travel by bus from Madrid to Santander
FAQs for Madrid to Santander bus
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What equipment is available for the Madrid Santander bus route?
Available seat classes which are offered on the bus route Madrid to Santander
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
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