Which bus from Madrid to Santander is the best?
Check the bus schedule for Madrid to Santander. Here is a selection of the cheapest coach trips for the next days from bus operators like ALSA or FlixBus. To see the full timetable for all coaches just use or search and compare.
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ALSA | 5h 50m | 08:00 | Madrid | Avenida de América Coach Station | 13:50 | Santander | Coach Station | Economy | £34 |
A Bus from ALSA goes from Avenida de América Coach Station, Madrid (Spain) at 18/12/2025 08:00:00 to Coach Station, Santander (Spain) arriving at 18/12/2025 13:50:00. 50 Economy ticket for £34 per person are available. Travel duration is 5h 50m
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| ALSA | 5h 45m | 10:30 | Madrid | Avenida de Aragon | 16:15 | Santander | Coach Station | Basic | £35 |
A Bus from ALSA goes from Avenida de Aragon, Madrid (Spain) at 18/12/2025 10:30:00 to Coach Station, Santander (Spain) arriving at 18/12/2025 16:15:00. 50 Basic ticket for £35 per person are available. Travel duration is 5h 45m
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| ALSA | 5h 45m | 16:30 | Madrid | Avenida de América Coach Station | 22:15 | Santander | Coach Station | Economy | £35 |
A Bus from ALSA goes from Avenida de América Coach Station, Madrid (Spain) at 18/12/2025 16:30:00 to Coach Station, Santander (Spain) arriving at 18/12/2025 22:15:00. 50 Economy ticket for £35 per person are available. Travel duration is 5h 45m
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| FlixBus | 16h 40m | 16:40 | Madrid | Sur Bus Station | 09:20 | Santander | Coach Station | Economy | £59 |
A Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 18/12/2025 16:40:00 to Coach Station, Santander (Spain) arriving at 19/12/2025 09:20:00. 50 Economy ticket for £59 per person are available. Travel duration is 16h 40m
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| FlixBus | 19h 20m | 23:30 | Madrid | Sur Bus Station | 18:50 | Santander | Coach Station | Economy | £83 |
A Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 18/12/2025 23:30:00 to Coach Station, Santander (Spain) arriving at 19/12/2025 18:50:00. 50 Economy ticket for £83 per person are available. Travel duration is 19h 20m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ALSA | 5h 50m | 08:00 | Madrid | Avenida de América Coach Station | 13:50 | Santander | Coach Station | Economy | £34 |
A Bus from ALSA goes from Avenida de América Coach Station, Madrid (Spain) at 19/12/2025 08:00:00 to Coach Station, Santander (Spain) arriving at 19/12/2025 13:50:00. 50 Economy ticket for £34 per person are available. Travel duration is 5h 50m
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| ALSA | 5h 45m | 10:30 | Madrid | Avenida de América Coach Station | 16:15 | Santander | Coach Station | Economy | £35 |
A Bus from ALSA goes from Avenida de América Coach Station, Madrid (Spain) at 19/12/2025 10:30:00 to Coach Station, Santander (Spain) arriving at 19/12/2025 16:15:00. 50 Economy ticket for £35 per person are available. Travel duration is 5h 45m
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| ALSA | 5h 30m | 13:00 | Madrid | Avenida de América Coach Station | 18:30 | Santander | Coach Station | Economy | £35 |
A Bus from ALSA goes from Avenida de América Coach Station, Madrid (Spain) at 19/12/2025 13:00:00 to Coach Station, Santander (Spain) arriving at 19/12/2025 18:30:00. 50 Economy ticket for £35 per person are available. Travel duration is 5h 30m
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| FlixBus | 16h 40m | 16:40 | Madrid | Sur Bus Station | 09:20 | Santander | Coach Station | Economy | £77 |
A Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 19/12/2025 16:40:00 to Coach Station, Santander (Spain) arriving at 20/12/2025 09:20:00. 50 Economy ticket for £77 per person are available. Travel duration is 16h 40m
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| FlixBus | 19h 20m | 23:30 | Madrid | Sur Bus Station | 18:50 | Santander | Coach Station | Economy | £79 |
A Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 19/12/2025 23:30:00 to Coach Station, Santander (Spain) arriving at 20/12/2025 18:50:00. 50 Economy ticket for £79 per person are available. Travel duration is 19h 20m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ALSA | 5h 50m | 08:00 | Madrid | Avenida de América Coach Station | 13:50 | Santander | Coach Station | Economy | £34 |
A Bus from ALSA goes from Avenida de América Coach Station, Madrid (Spain) at 20/12/2025 08:00:00 to Coach Station, Santander (Spain) arriving at 20/12/2025 13:50:00. 50 Economy ticket for £34 per person are available. Travel duration is 5h 50m
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| ALSA | 5h 30m | 13:00 | Madrid | Avenida de América Coach Station | 18:30 | Santander | Coach Station | Economy | £35 |
A Bus from ALSA goes from Avenida de América Coach Station, Madrid (Spain) at 20/12/2025 13:00:00 to Coach Station, Santander (Spain) arriving at 20/12/2025 18:30:00. 50 Economy ticket for £35 per person are available. Travel duration is 5h 30m
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| ALSA | 5h 45m | 16:30 | Madrid | Avenida de América Coach Station | 22:15 | Santander | Coach Station | Economy | £35 |
A Bus from ALSA goes from Avenida de América Coach Station, Madrid (Spain) at 20/12/2025 16:30:00 to Coach Station, Santander (Spain) arriving at 20/12/2025 22:15:00. 50 Economy ticket for £35 per person are available. Travel duration is 5h 45m
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| FlixBus | 19h 20m | 23:30 | Madrid | Sur Bus Station | 18:50 | Santander | Coach Station | Economy | £69 |
A Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 20/12/2025 23:30:00 to Coach Station, Santander (Spain) arriving at 21/12/2025 18:50:00. 50 Economy ticket for £69 per person are available. Travel duration is 19h 20m
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| FlixBus | 16h 40m | 16:40 | Madrid | Sur Bus Station | 09:20 | Santander | Coach Station | Economy | £103 |
A Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 20/12/2025 16:40:00 to Coach Station, Santander (Spain) arriving at 21/12/2025 09:20:00. 50 Economy ticket for £103 per person are available. Travel duration is 16h 40m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ALSA | 5h 50m | 08:00 | Madrid | Avenida de América Coach Station | 13:50 | Santander | Coach Station | Economy | £34 |
A Bus from ALSA goes from Avenida de América Coach Station, Madrid (Spain) at 21/12/2025 08:00:00 to Coach Station, Santander (Spain) arriving at 21/12/2025 13:50:00. 50 Economy ticket for £34 per person are available. Travel duration is 5h 50m
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| ALSA | 5h 45m | 10:30 | Madrid | Avenida de América Coach Station | 16:15 | Santander | Coach Station | Economy | £35 |
A Bus from ALSA goes from Avenida de América Coach Station, Madrid (Spain) at 21/12/2025 10:30:00 to Coach Station, Santander (Spain) arriving at 21/12/2025 16:15:00. 50 Economy ticket for £35 per person are available. Travel duration is 5h 45m
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| ALSA | 5h 30m | 13:00 | Madrid | Avenida de América Coach Station | 18:30 | Santander | Coach Station | Economy | £35 |
A Bus from ALSA goes from Avenida de América Coach Station, Madrid (Spain) at 21/12/2025 13:00:00 to Coach Station, Santander (Spain) arriving at 21/12/2025 18:30:00. 50 Economy ticket for £35 per person are available. Travel duration is 5h 30m
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| FlixBus | 16h 40m | 16:40 | Madrid | Sur Bus Station | 09:20 | Santander | Coach Station | Economy | £74 |
A Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 21/12/2025 16:40:00 to Coach Station, Santander (Spain) arriving at 22/12/2025 09:20:00. 50 Economy ticket for £74 per person are available. Travel duration is 16h 40m
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| FlixBus | 19h 20m | 23:30 | Madrid | Sur Bus Station | 18:50 | Santander | Coach Station | Economy | £95 |
A Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 21/12/2025 23:30:00 to Coach Station, Santander (Spain) arriving at 22/12/2025 18:50:00. 50 Economy ticket for £95 per person are available. Travel duration is 19h 20m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ALSA | 5h 45m | 10:30 | Madrid | Avenida de América Coach Station | 16:15 | Santander | Coach Station | Economy | £35 |
A Bus from ALSA goes from Avenida de América Coach Station, Madrid (Spain) at 22/12/2025 10:30:00 to Coach Station, Santander (Spain) arriving at 22/12/2025 16:15:00. 50 Economy ticket for £35 per person are available. Travel duration is 5h 45m
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| ALSA | 5h 30m | 13:00 | Madrid | Avenida de América Coach Station | 18:30 | Santander | Coach Station | Economy | £35 |
A Bus from ALSA goes from Avenida de América Coach Station, Madrid (Spain) at 22/12/2025 13:00:00 to Coach Station, Santander (Spain) arriving at 22/12/2025 18:30:00. 50 Economy ticket for £35 per person are available. Travel duration is 5h 30m
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| ALSA | 5h 45m | 16:30 | Madrid | Avenida de América Coach Station | 22:15 | Santander | Coach Station | Economy | £35 |
A Bus from ALSA goes from Avenida de América Coach Station, Madrid (Spain) at 22/12/2025 16:30:00 to Coach Station, Santander (Spain) arriving at 22/12/2025 22:15:00. 50 Economy ticket for £35 per person are available. Travel duration is 5h 45m
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| FlixBus | 16h 40m | 16:40 | Madrid | Sur Bus Station | 09:20 | Santander | Coach Station | Economy | £78 |
A Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 22/12/2025 16:40:00 to Coach Station, Santander (Spain) arriving at 23/12/2025 09:20:00. 50 Economy ticket for £78 per person are available. Travel duration is 16h 40m
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| FlixBus | 19h 20m | 23:30 | Madrid | Sur Bus Station | 18:50 | Santander | Coach Station | Economy | £85 |
A Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 22/12/2025 23:30:00 to Coach Station, Santander (Spain) arriving at 23/12/2025 18:50:00. 50 Economy ticket for £85 per person are available. Travel duration is 19h 20m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ALSA | 5h 50m | 08:00 | Madrid | Avenida de América Coach Station | 13:50 | Santander | Coach Station | Economy | £34 |
A Bus from ALSA goes from Avenida de América Coach Station, Madrid (Spain) at 23/12/2025 08:00:00 to Coach Station, Santander (Spain) arriving at 23/12/2025 13:50:00. 50 Economy ticket for £34 per person are available. Travel duration is 5h 50m
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| ALSA | 5h 45m | 16:30 | Madrid | Avenida de América Coach Station | 22:15 | Santander | Coach Station | Economy | £35 |
A Bus from ALSA goes from Avenida de América Coach Station, Madrid (Spain) at 23/12/2025 16:30:00 to Coach Station, Santander (Spain) arriving at 23/12/2025 22:15:00. 50 Economy ticket for £35 per person are available. Travel duration is 5h 45m
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| ALSA | 5h 30m | 18:30 | Madrid | Avenida de América Coach Station | 00:00 | Santander | Coach Station | Economy | £35 |
A Bus from ALSA goes from Avenida de América Coach Station, Madrid (Spain) at 23/12/2025 18:30:00 to Coach Station, Santander (Spain) arriving at 24/12/2025 00:00:00. 50 Economy ticket for £35 per person are available. Travel duration is 5h 30m
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| FlixBus | 16h 40m | 16:40 | Madrid | Sur Bus Station | 09:20 | Santander | Coach Station | Economy | £63 |
A Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 23/12/2025 16:40:00 to Coach Station, Santander (Spain) arriving at 24/12/2025 09:20:00. 50 Economy ticket for £63 per person are available. Travel duration is 16h 40m
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| FlixBus | 19h 20m | 23:30 | Madrid | Sur Bus Station | 18:50 | Santander | Coach Station | Economy | £100 |
A Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 23/12/2025 23:30:00 to Coach Station, Santander (Spain) arriving at 24/12/2025 18:50:00. 50 Economy ticket for £100 per person are available. Travel duration is 19h 20m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ALSA | 5h 50m | 08:00 | Madrid | Avenida de América Coach Station | 13:50 | Santander | Coach Station | Economy | £34 |
A Bus from ALSA goes from Avenida de América Coach Station, Madrid (Spain) at 24/12/2025 08:00:00 to Coach Station, Santander (Spain) arriving at 24/12/2025 13:50:00. 50 Economy ticket for £34 per person are available. Travel duration is 5h 50m
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| ALSA | 5h 45m | 10:30 | Madrid | Avenida de América Coach Station | 16:15 | Santander | Coach Station | Economy | £35 |
A Bus from ALSA goes from Avenida de América Coach Station, Madrid (Spain) at 24/12/2025 10:30:00 to Coach Station, Santander (Spain) arriving at 24/12/2025 16:15:00. 50 Economy ticket for £35 per person are available. Travel duration is 5h 45m
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| ALSA | 5h 30m | 13:00 | Madrid | Avenida de América Coach Station | 18:30 | Santander | Coach Station | Economy | £35 |
A Bus from ALSA goes from Avenida de América Coach Station, Madrid (Spain) at 24/12/2025 13:00:00 to Coach Station, Santander (Spain) arriving at 24/12/2025 18:30:00. 50 Economy ticket for £35 per person are available. Travel duration is 5h 30m
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| FlixBus | 19h 20m | 23:30 | Madrid | Sur Bus Station | 18:50 | Santander | Coach Station | Economy | £75 |
A Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 24/12/2025 23:30:00 to Coach Station, Santander (Spain) arriving at 25/12/2025 18:50:00. 50 Economy ticket for £75 per person are available. Travel duration is 19h 20m
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| FlixBus | 16h 40m | 16:40 | Madrid | Sur Bus Station | 09:20 | Santander | Coach Station | Economy | £87 |
A Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 24/12/2025 16:40:00 to Coach Station, Santander (Spain) arriving at 25/12/2025 09:20:00. 50 Economy ticket for £87 per person are available. Travel duration is 16h 40m
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Best Price Offer: The price for the cheapest coach from Madrid to Santander is £9 on 06/01/2026. Flexible travellers save on ticket prices.
What is the best day and time to travel by bus between Madrid and Santander?
All facts for Madrid to Santander bus at a glance
Compare all coach operators like ALSA and FlixBus that travel daily 18 times by bus from Madrid to Santander in one click. Book your Madrid to Santander bus ticket starting from £9!
| Cheapest Bus | £9 |
| Fastest Bus | 5h 30m |
| Earliest Coach | 08:00 |
| Latest Coach | 23:30 |
| Daily Bus Connections | 18 Ø |
| Distance | 338.8 km |
| Coach Companies | ALSA and FlixBus |
What are the cheapest coach tickets from Madrid to Santander?
Every day, 18 buses from 2 coach companies leave Madrid for Santander. Check the table below to find the cheapest prices for coach tickets for this route, starting from 18/12/2025 and for the following days. Make sure get the cheapest bus ticket!
The cheapest time to travel from Madrid to Santander
How to save money travelling from Madrid to Santander
Book the ticket from Madrid to Santander in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the coach from Madrid to Santander, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Madrid to Santander are also emptier.Check for bus deals and promotions for all bus companies in this route. On CheckMyBus we show special offers directly in the coach trip on our search. Sign-up and check or deals sections and get notifications on our latest travel hacks.
All bus stations and stops in Madrid and Santander
Here is a map with all coach stations in Madrid and Santander. Compare which stop is closest to your destination to save time to find the fastest buses and connections.
Compare the bus with other modes of transport
All you need to know when you travel by bus from Madrid to Santander
FAQs for Madrid to Santander bus
How much does a Madrid Santander coach trip cost?
How much could I save by comparing buses from Madrid to Santander?
How many connections are available for the Madrid Santander route on average every day?
How long does a bus to Santander from Madrid take?
What time is the first bus from Madrid to Santander?
What time is the last coach from Madrid to Santander?
Which bus companies serve the Madrid Santander route?
Is there a direct bus between Madrid and Santander?
What can I take with me on the bus to Santander from Madrid?
What equipment is available for the Madrid Santander bus route?
How does CheckMyBus find the best coach deals from Madrid to Santander?
How does CheckMyBus technology work for trips from Madrid to Santander?
Available seat classes which are offered on the bus route Madrid to Santander
Name referring to the typical seat you will find with companies that don’t distinguish between different classes.
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
More bus routes to Madrid and to Santander
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