Coach La Serena to Mendoza from £74

Which bus from La Serena to Mendoza is the best?

Check the bus schedule for La Serena to Mendoza. Here is a selection of the cheapest coach trips for the next days from bus operators like CATA Internacional. To see the full timetable for all coaches just use or search and compare.

today

tomorrow

£74

Monday

Tuesday

Wednesday

Thursday

Friday

Cheapest bus trips tomorrow
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	CATA Internacional	13h 15m	17:30	La Serena	Central Coach Station	06:45	Mendoza	Bus Station		Premium Economy	£74	A Bus from CATA Internacional goes from Central Coach Station, La Serena (Chile) at 22/03/2026 17:30:00 to Bus Station, Mendoza (Argentina) arriving at 23/03/2026 06:45:00. 50 Premium Economy ticket for £74 per person are available. Travel duration is 13h 15m

Did you know that if you travel from La Serena to Mendoza via Santiago, RM, you can save more than £48? You can find the corresponding connections below.
- Buses Romani
  
  15h 0m
  
  0
  
  00:45
  
  La Serena
  Central Coach Station
  
  07:00
  
  Santiago, RM
  Sur Bus Station
  
  0
  
  Premium Economy
  
  £7
  
  A Bus from Buses Romani goes from Central Coach Station, La Serena (Chile) at 24/03/2026 00:45:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 24/03/2026 07:00:00. 50 Premium Economy ticket for £7 per person are available. Travel duration is 6h 15m
- Coitram
  
  8h 0m
  
  0
  
  07:45
  
  Santiago, RM
  Sur Bus Station
  
  15:45
  
  Mendoza
  Bus Station
  
  0
  
  Basic
  
  £19
  
  A Bus from Coitram goes from Sur Bus Station, Santiago, RM (Chile) at 24/03/2026 07:45:00 to Bus Station, Mendoza (Argentina) arriving at 24/03/2026 15:45:00. 50 Basic ticket for £19 per person are available. Travel duration is 8h 0m
Travel time is 1h 45m longer, but you will save £48

Best Price Offer: The price for the cheapest coach from La Serena to Mendoza is £74 on 22/03/2026. Flexible travellers save on ticket prices.

All facts for La Serena to Mendoza bus at a glance

Compare all coach operators like CATA Internacional that travel daily 7 times by bus from La Serena to Mendoza in one click. Book your La Serena to Mendoza bus ticket starting from £74!

Cheapest Bus	£74
Fastest Bus	13h 15m
Earliest Coach	17:30
Latest Coach	17:30
Daily Bus Connections	7 Ø
Distance	403.0 km
Coach Companies	CATA Internacional

What are the cheapest coach tickets from La Serena to Mendoza?

Every day, 7 buses from 1 coach companies leave La Serena for Mendoza. Check the table below to find the cheapest prices for coach tickets for this route, starting from 21/03/2026 and for the following days. Make sure get the cheapest bus ticket!

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday

Monday 16/03

Tuesday 17/03

Wednesday 18/03

Thursday 19/03

Friday 20/03

Saturday 21/03

Sunday 22/03

£74

Monday 23/03

Tuesday 24/03

Wednesday 25/03

Thursday 26/03

Friday 27/03

Saturday 28/03

Sunday 29/03

£74

Monday 30/03

Tuesday 31/03

Wednesday 01/04

Thursday 02/04

Friday 03/04

Saturday 04/04

Sunday 05/04

£74

Monday 06/04

Tuesday 07/04

Wednesday 08/04

Thursday 09/04

Friday 10/04

Saturday 11/04

Sunday 12/04

How to save money travelling from La Serena to Mendoza

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying higher prices for your trip? Plan your bus trips smartly. Here are a few hacks to save money on your coach journey.

Book the ticket from La Serena to Mendoza in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the coach from La Serena to Mendoza, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from La Serena to Mendoza are also emptier.

Check for bus deals and promotions for all bus companies in this route. On CheckMyBus we show special offers directly in the coach trip on our search. Sign-up and check or deals sections and get notifications on our latest travel hacks.

All bus stations and stops in La Serena and Mendoza

Here is a map with all coach stations in La Serena and Mendoza. Compare which stop is closest to your destination to save time to find the fastest buses and connections.

Avda. Fco de Aguirre Station

Avenida Francisco de Aguirre 410

Central Coach Station

Avenida El Santo 1475

El Sto, 1060

terminal de buses covalle bus

Rotonda

Bus Station

Juan B. Alberdi s/n

Hotel Internacional

Av. Sarmiento 720

Hotel Hyatt

Chile 1124

Hotel NH Cordillera

1324 1324

Casa Juri

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from La Serena to Mendoza? Compare all modes of transports from La Serena to Mendoza.

All you need to know when you travel by bus from La Serena to Mendoza

Check all information on comfort and services on the coaches from La Serena to Mendoza. Which seat classes are available or what are the amenities of operators on your coach trip? Below you´ll find answers to your questions.

FAQs for La Serena to Mendoza bus

How much does a La Serena Mendoza coach trip cost?

This depends on, among other things, the day and travel time. The cheapest ticket for the La Serena Mendoza bus trip is available from £74 and takes 13h 15m. Compare offers and save money!

How much could I save by comparing buses from La Serena to Mendoza?

This connection is offered by 1 companies with ticket prices ranging from £74 to £94. Therefore, we suggest booking your ticket as soon as possible to ensure you’ll get the cheapest bus trip to Mendoza.

How many connections are available for the La Serena Mendoza route on average every day?

Each day, the bus route from La Serena to Mendoza is offered by roughly 7 busses. By using our search, you can compare bus schedules and find your ideal trip.

How long does a bus to Mendoza from La Serena take?

The quickest coach from La Serena to Mendoza is provided by CATA Internacional and takes 13h 15m. Coach tickets for this connection cost £88. However, keep in mind that the connection can take longer due to traffic.

What time is the first bus from La Serena to Mendoza?

The earliest bus to Mendoza departs from La Serena at 17:30. In this context, information about departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

What time is the last coach from La Serena to Mendoza?

The latest bus to Mendoza departs from La Serena at 17:30. Please note that departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

Which bus companies serve the La Serena Mendoza route?

Passengers looking to travel from La Serena to Mendoza can travel with CATA Internacional. Compare all available bus tickets with our search to book the trip that works best for you.

Is there a direct bus between La Serena and Mendoza?

You can check all the direct connections between La Serena and Mendoza by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: CATA Internacional.

What can I take with me on the bus to Mendoza from La Serena?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the bus for the La Serena Mendoza bus route free of charge. Simply use our search to find a coach that is best suited to your needs for your planned travel date.

What equipment is available for the La Serena Mendoza bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make travelling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from La Serena to Mendoza on your planned travel date.

How does CheckMyBus find the best coach deals from La Serena to Mendoza?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 7 daily trips between La Serena and Mendoza. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from La Serena to Mendoza?

Prices and availability for 7 trips between La Serena and Mendoza change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route La Serena to Mendoza

Premium Economy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

More bus routes to La Serena and to Mendoza

Here’s an overview of the most popular bus routes to La Serena and to Mendoza. Simply click on the connection of your choice, and you’ll find all the details about your bus route!