Which bus from Brno to Prague is the best?
Check the bus schedule for Brno to Prague. Here is a selection of the cheapest coach trips for the next days from bus operators like FlixBus, RegioJet or A-Express. To see the full timetable for all coaches just use or search and compare.
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 2h 30m | 20:50 | Brno | Hotel Grand | 23:20 | Prague | Wilsonova Coach Station | Economy | £7 |
A Bus from FlixBus goes from Hotel Grand, Brno (Czech Republic) at 21/03/2026 20:50:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 21/03/2026 23:20:00. 50 Economy ticket for £7 per person are available. Travel duration is 2h 30m
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| FlixBus | 2h 25m | 23:30 | Brno | Hotel Grand | 01:55 | Prague | Wilsonova Coach Station | Economy | £7 |
A Bus from FlixBus goes from Hotel Grand, Brno (Czech Republic) at 21/03/2026 23:30:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 22/03/2026 01:55:00. 50 Economy ticket for £7 per person are available. Travel duration is 2h 25m
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| RegioJet | 2h 30m | 03:30 | Brno | Benesova Bus Station | 06:00 | Prague | ÚAN Florenc | Economy | £7 |
A Bus from RegioJet goes from Benesova Bus Station, Brno (Czech Republic) at 21/03/2026 03:30:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 21/03/2026 06:00:00. 50 Economy ticket for £7 per person are available. Travel duration is 2h 30m
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| RegioJet | 2h 30m | 14:00 | Brno | Benesova Bus Station | 16:30 | Prague | ÚAN Florenc | Economy | £7 |
A Bus from RegioJet goes from Benesova Bus Station, Brno (Czech Republic) at 21/03/2026 14:00:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 21/03/2026 16:30:00. 50 Economy ticket for £7 per person are available. Travel duration is 2h 30m
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| A-Express | 2h 35m | 02:15 | Brno | Hotel Grand | 04:50 | Prague | ÚAN Florenc | Economy | £14 |
A Bus from A-Express goes from Hotel Grand, Brno (Czech Republic) at 21/03/2026 02:15:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 21/03/2026 04:50:00. 50 Economy ticket for £14 per person are available. Travel duration is 2h 35m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 2h 25m | 01:30 | Brno | Hotel Grand | 03:55 | Prague | Wilsonova Coach Station | Economy | £6 |
A Bus from FlixBus goes from Hotel Grand, Brno (Czech Republic) at 22/03/2026 01:30:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 22/03/2026 03:55:00. 50 Economy ticket for £6 per person are available. Travel duration is 2h 25m
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| FlixBus | 2h 35m | 05:25 | Brno | Hotel Grand | 08:00 | Prague | Wilsonova Coach Station | Economy | £6 |
A Bus from FlixBus goes from Hotel Grand, Brno (Czech Republic) at 22/03/2026 05:25:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 22/03/2026 08:00:00. 50 Economy ticket for £6 per person are available. Travel duration is 2h 35m
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| RegioJet | 2h 30m | 03:30 | Brno | Benesova Bus Station | 06:00 | Prague | ÚAN Florenc | Economy | £7 |
A Bus from RegioJet goes from Benesova Bus Station, Brno (Czech Republic) at 22/03/2026 03:30:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 22/03/2026 06:00:00. 50 Economy ticket for £7 per person are available. Travel duration is 2h 30m
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| RegioJet | 2h 55m | 05:30 | Brno | Benesova Bus Station | 08:25 | Prague | ÚAN Florenc | Economy | £7 |
A Bus from RegioJet goes from Benesova Bus Station, Brno (Czech Republic) at 22/03/2026 05:30:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 22/03/2026 08:25:00. 50 Economy ticket for £7 per person are available. Travel duration is 2h 55m
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| A-Express | 2h 35m | 02:15 | Brno | Hotel Grand | 04:50 | Prague | ÚAN Florenc | Economy | £12 |
A Bus from A-Express goes from Hotel Grand, Brno (Czech Republic) at 22/03/2026 02:15:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 22/03/2026 04:50:00. 50 Economy ticket for £12 per person are available. Travel duration is 2h 35m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 2h 25m | 01:30 | Brno | Hotel Grand | 03:55 | Prague | Wilsonova Coach Station | Economy | £6 |
A Bus from FlixBus goes from Hotel Grand, Brno (Czech Republic) at 23/03/2026 01:30:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 23/03/2026 03:55:00. 50 Economy ticket for £6 per person are available. Travel duration is 2h 25m
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| FlixBus | 2h 35m | 05:25 | Brno | Hotel Grand | 08:00 | Prague | Wilsonova Coach Station | Economy | £6 |
A Bus from FlixBus goes from Hotel Grand, Brno (Czech Republic) at 23/03/2026 05:25:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 23/03/2026 08:00:00. 50 Economy ticket for £6 per person are available. Travel duration is 2h 35m
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| RegioJet | 2h 30m | 03:30 | Brno | Benesova Bus Station | 06:00 | Prague | ÚAN Florenc | Economy | £7 |
A Bus from RegioJet goes from Benesova Bus Station, Brno (Czech Republic) at 23/03/2026 03:30:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 23/03/2026 06:00:00. 50 Economy ticket for £7 per person are available. Travel duration is 2h 30m
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| RegioJet | 2h 55m | 07:00 | Brno | Benesova Bus Station | 09:55 | Prague | ÚAN Florenc | Economy | £7 |
A Bus from RegioJet goes from Benesova Bus Station, Brno (Czech Republic) at 23/03/2026 07:00:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 23/03/2026 09:55:00. 50 Economy ticket for £7 per person are available. Travel duration is 2h 55m
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| A-Express | 2h 35m | 02:15 | Brno | Hotel Grand | 04:50 | Prague | ÚAN Florenc | Economy | £14 |
A Bus from A-Express goes from Hotel Grand, Brno (Czech Republic) at 23/03/2026 02:15:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 23/03/2026 04:50:00. 50 Economy ticket for £14 per person are available. Travel duration is 2h 35m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 2h 45m | 17:10 | Brno | Hotel Grand | 19:55 | Prague | ÚAN Florenc | Economy | £5 |
A Bus from FlixBus goes from Hotel Grand, Brno (Czech Republic) at 24/03/2026 17:10:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 24/03/2026 19:55:00. 50 Economy ticket for £5 per person are available. Travel duration is 2h 45m
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| FlixBus | 2h 35m | 20:10 | Brno | Hotel Grand | 22:45 | Prague | ÚAN Florenc | Economy | £5 |
A Bus from FlixBus goes from Hotel Grand, Brno (Czech Republic) at 24/03/2026 20:10:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 24/03/2026 22:45:00. 50 Economy ticket for £5 per person are available. Travel duration is 2h 35m
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| RegioJet | 2h 30m | 03:30 | Brno | Benesova Bus Station | 06:00 | Prague | ÚAN Florenc | Economy | £7 |
A Bus from RegioJet goes from Benesova Bus Station, Brno (Czech Republic) at 24/03/2026 03:30:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 24/03/2026 06:00:00. 50 Economy ticket for £7 per person are available. Travel duration is 2h 30m
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| RegioJet | 2h 55m | 07:00 | Brno | Benesova Bus Station | 09:55 | Prague | ÚAN Florenc | Economy | £7 |
A Bus from RegioJet goes from Benesova Bus Station, Brno (Czech Republic) at 24/03/2026 07:00:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 24/03/2026 09:55:00. 50 Economy ticket for £7 per person are available. Travel duration is 2h 55m
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| A-Express | 2h 35m | 02:15 | Brno | Hotel Grand | 04:50 | Prague | ÚAN Florenc | Economy | £12 |
A Bus from A-Express goes from Hotel Grand, Brno (Czech Republic) at 24/03/2026 02:15:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 24/03/2026 04:50:00. 50 Economy ticket for £12 per person are available. Travel duration is 2h 35m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 2h 25m | 01:30 | Brno | Hotel Grand | 03:55 | Prague | Wilsonova Coach Station | Economy | £6 |
A Bus from FlixBus goes from Hotel Grand, Brno (Czech Republic) at 25/03/2026 01:30:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 25/03/2026 03:55:00. 50 Economy ticket for £6 per person are available. Travel duration is 2h 25m
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| FlixBus | 2h 40m | 09:40 | Brno | Hotel Grand | 12:20 | Prague | Wilsonova Coach Station | Economy | £6 |
A Bus from FlixBus goes from Hotel Grand, Brno (Czech Republic) at 25/03/2026 09:40:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 25/03/2026 12:20:00. 50 Economy ticket for £6 per person are available. Travel duration is 2h 40m
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| FlixBus | 2h 40m | 10:50 | Brno | Hotel Grand | 13:30 | Prague | Wilsonova Coach Station | Economy | £6 |
A Bus from FlixBus goes from Hotel Grand, Brno (Czech Republic) at 25/03/2026 10:50:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 25/03/2026 13:30:00. 50 Economy ticket for £6 per person are available. Travel duration is 2h 40m
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| A-Express | 2h 35m | 02:15 | Brno | Hotel Grand | 04:50 | Prague | ÚAN Florenc | Economy | £12 |
A Bus from A-Express goes from Hotel Grand, Brno (Czech Republic) at 25/03/2026 02:15:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 25/03/2026 04:50:00. 50 Economy ticket for £12 per person are available. Travel duration is 2h 35m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 2h 30m | 20:50 | Brno | Hotel Grand | 23:20 | Prague | Wilsonova Coach Station | Economy | £5 |
A Bus from FlixBus goes from Hotel Grand, Brno (Czech Republic) at 26/03/2026 20:50:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 26/03/2026 23:20:00. 50 Economy ticket for £5 per person are available. Travel duration is 2h 30m
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| FlixBus | 2h 35m | 20:10 | Brno | Hotel Grand | 22:45 | Prague | ÚAN Florenc | Economy | £5 |
A Bus from FlixBus goes from Hotel Grand, Brno (Czech Republic) at 26/03/2026 20:10:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 26/03/2026 22:45:00. 50 Economy ticket for £5 per person are available. Travel duration is 2h 35m
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| RegioJet | 2h 30m | 03:30 | Brno | Benesova Bus Station | 06:00 | Prague | ÚAN Florenc | Economy | £7 |
A Bus from RegioJet goes from Benesova Bus Station, Brno (Czech Republic) at 26/03/2026 03:30:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 26/03/2026 06:00:00. 50 Economy ticket for £7 per person are available. Travel duration is 2h 30m
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| RegioJet | 2h 55m | 07:00 | Brno | Benesova Bus Station | 09:55 | Prague | ÚAN Florenc | Economy | £7 |
A Bus from RegioJet goes from Benesova Bus Station, Brno (Czech Republic) at 26/03/2026 07:00:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 26/03/2026 09:55:00. 50 Economy ticket for £7 per person are available. Travel duration is 2h 55m
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| A-Express | 2h 35m | 02:15 | Brno | Hotel Grand | 04:50 | Prague | Wilsonova Coach Station | Economy | £13 |
A Bus from A-Express goes from Hotel Grand, Brno (Czech Republic) at 26/03/2026 02:15:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 26/03/2026 04:50:00. 50 Economy ticket for £13 per person are available. Travel duration is 2h 35m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 2h 35m | 20:10 | Brno | Hotel Grand | 22:45 | Prague | ÚAN Florenc | Economy | £6 |
A Bus from FlixBus goes from Hotel Grand, Brno (Czech Republic) at 27/03/2026 20:10:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 27/03/2026 22:45:00. 50 Economy ticket for £6 per person are available. Travel duration is 2h 35m
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| FlixBus | 2h 25m | 01:30 | Brno | Hotel Grand | 03:55 | Prague | Wilsonova Coach Station | Economy | £7 |
A Bus from FlixBus goes from Hotel Grand, Brno (Czech Republic) at 27/03/2026 01:30:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 27/03/2026 03:55:00. 50 Economy ticket for £7 per person are available. Travel duration is 2h 25m
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| RegioJet | 2h 20m | 21:20 | Brno | Benesova Bus Station | 23:40 | Prague | ÚAN Florenc | Economy | £7 |
A Bus from RegioJet goes from Benesova Bus Station, Brno (Czech Republic) at 27/03/2026 21:20:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 27/03/2026 23:40:00. 50 Economy ticket for £7 per person are available. Travel duration is 2h 20m
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| RegioJet | 2h 55m | 05:30 | Brno | Benesova Bus Station | 08:25 | Prague | ÚAN Florenc | Economy | £9 |
A Bus from RegioJet goes from Benesova Bus Station, Brno (Czech Republic) at 27/03/2026 05:30:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 27/03/2026 08:25:00. 50 Economy ticket for £9 per person are available. Travel duration is 2h 55m
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| A-Express | 2h 35m | 02:15 | Brno | Hotel Grand | 04:50 | Prague | ÚAN Florenc | Economy | £14 |
A Bus from A-Express goes from Hotel Grand, Brno (Czech Republic) at 27/03/2026 02:15:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 27/03/2026 04:50:00. 50 Economy ticket for £14 per person are available. Travel duration is 2h 35m
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Best Price Offer: The price for the cheapest coach from Brno to Prague is £5 on 24/03/2026. Flexible travellers save on ticket prices.
What is the best day and time to travel by bus between Brno and Prague?
All facts for Brno to Prague bus at a glance
Compare all coach operators like FlixBus, RegioJet and A-Express that travel daily 63 times by bus from Brno to Prague in one click. Book your Brno to Prague bus ticket starting from £5!
| Cheapest Bus | £5 |
| Fastest Bus | 2h 0m |
| Earliest Coach | 01:30 |
| Latest Coach | 23:59 |
| Daily Bus Connections | 63 Ø |
| Distance | 184.3 km |
| Coach Companies | FlixBus, RegioJet and A-Express |
What are the cheapest coach tickets from Brno to Prague?
Every day, 63 buses from 3 coach companies leave Brno for Prague. Check the table below to find the cheapest prices for coach tickets for this route, starting from 21/03/2026 and for the following days. Make sure get the cheapest bus ticket!
The cheapest time to travel from Brno to Prague
How to save money travelling from Brno to Prague
Book the ticket from Brno to Prague in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the coach from Brno to Prague, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Brno to Prague are also emptier.Check for bus deals and promotions for all bus companies in this route. On CheckMyBus we show special offers directly in the coach trip on our search. Sign-up and check or deals sections and get notifications on our latest travel hacks.
All bus stations and stops in Brno and Prague
Here is a map with all coach stations in Brno and Prague. Compare which stop is closest to your destination to save time to find the fastest buses and connections.
Compare the bus with other modes of transport
All you need to know when you travel by bus from Brno to Prague
FAQs for Brno to Prague bus
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Available seat classes which are offered on the bus route Brno to Prague
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
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