What is the best way to travel from St. Louis, MO to Chicago?
Looking for a trip? Check and compare all the available Flights and Buses to Chicago from St. Louis, MO. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 2 available companies to find your perfect trip!
What is the cheapest way to reach Chicago from St. Louis, MO?
You can reach Chicago with just £25 by taking a Bus from FlixBus, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
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Frontier Airlines24h 10m017:42St. Louis Lambert AirportSt. Louis Lambert Airport17:52Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 04/02/2026 17:42:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 05/02/2026 17:52:00. 50 Economy ticket for £203 per person are available. Travel duration is 24h 10m
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Frontier Airlines25h 59m017:42St. Louis Lambert AirportSt. Louis Lambert Airport19:41Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 04/02/2026 17:42:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 05/02/2026 19:41:00. 50 Economy ticket for £203 per person are available. Travel duration is 25h 59m
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United Airlines1h 35m013:15St. Louis Lambert AirportSt. Louis Lambert Airport14:50Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 04/02/2026 13:15:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 04/02/2026 14:50:00. 50 Economy ticket for £261 per person are available. Travel duration is 1h 35m
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United Airlines1h 37m011:20St. Louis Lambert AirportSt. Louis Lambert Airport12:57Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 04/02/2026 11:20:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 04/02/2026 12:57:00. 50 Economy ticket for £263 per person are available. Travel duration is 1h 37m
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Skyscanner1h 37m011:20St. Louis Lambert AirportSt. Louis Lambert Airport12:57Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Skyscanner goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 04/02/2026 11:20:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 04/02/2026 12:57:00. 50 Economy ticket for £263 per person are available. Travel duration is 1h 37m
Cheapest Flights Wednesday
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FlixBus7h 0m009:30St. Louis, MOGateway Station16:30ChicagoDowntown Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 05/02/2026 09:30:00 to Downtown Coach Station, Chicago (USA) arriving at 05/02/2026 16:30:00. 50 Economy ticket for £25 per person are available. Travel duration is 7h 0m
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Greyhound US12h 10m002:00St. Louis, MOGateway Station14:10ChicagoCanal & Van Buren0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 05/02/2026 02:00:00 to Canal & Van Buren, Chicago (USA) arriving at 05/02/2026 14:10:00. 50 Economy ticket for £27 per person are available. Travel duration is 12h 10m
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FlixBus6h 15m023:30St. Louis, MOGateway Station05:45ChicagoDowntown Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 05/02/2026 23:30:00 to Downtown Coach Station, Chicago (USA) arriving at 06/02/2026 05:45:00. 50 Economy ticket for £27 per person are available. Travel duration is 6h 15m
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Greyhound US12h 10m002:00St. Louis, MOGateway Station14:10ChicagoUnion Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 05/02/2026 02:00:00 to Union Station, Chicago (USA) arriving at 05/02/2026 14:10:00. 50 Economy ticket for £31 per person are available. Travel duration is 12h 10m
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Frontier Airlines16h 53m017:42St. Louis Lambert AirportSt. Louis Lambert Airport10:35Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 05/02/2026 17:42:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 06/02/2026 10:35:00. 50 Economy ticket for £66 per person are available. Travel duration is 16h 53m
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Frontier Airlines22h 28m022:01St. Louis Lambert AirportSt. Louis Lambert Airport20:29Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 05/02/2026 22:01:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 06/02/2026 20:29:00. 50 Economy ticket for £66 per person are available. Travel duration is 22h 28m
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Skyscanner1h 35m006:30St. Louis Lambert AirportSt. Louis Lambert Airport08:05Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Skyscanner goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 05/02/2026 06:30:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 05/02/2026 08:05:00. 50 Economy ticket for £152 per person are available. Travel duration is 1h 35m
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Skyscanner1h 35m008:05St. Louis Lambert AirportSt. Louis Lambert Airport09:40Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Skyscanner goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 05/02/2026 08:05:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 05/02/2026 09:40:00. 50 Economy ticket for £152 per person are available. Travel duration is 1h 35m
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Frontier Airlines26h 10m017:42St. Louis Lambert AirportSt. Louis Lambert Airport19:52Chicago Midway AirportChicago Midway Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 05/02/2026 17:42:00 to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 06/02/2026 19:52:00. 50 Economy ticket for £214 per person are available. Travel duration is 26h 10m
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United Airlines15h 59m007:00St. Louis Lambert AirportSt. Louis Lambert Airport22:59Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 05/02/2026 07:00:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 05/02/2026 22:59:00. 50 Economy ticket for £265 per person are available. Travel duration is 15h 59m
Cheapest Buses Thursday
Cheapest Flights Thursday
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FlixBus6h 15m023:30St. Louis, MOGateway Station05:45ChicagoDowntown Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 06/02/2026 23:30:00 to Downtown Coach Station, Chicago (USA) arriving at 07/02/2026 05:45:00. 50 Economy ticket for £34 per person are available. Travel duration is 6h 15m
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FlixBus5h 50m023:30St. Louis, MOGateway Station05:20Chicago95th Red Line Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 06/02/2026 23:30:00 to 95th Red Line Station, Chicago (USA) arriving at 07/02/2026 05:20:00. 50 Economy ticket for £35 per person are available. Travel duration is 5h 50m
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FlixBus7h 0m009:30St. Louis, MOGateway Station16:30ChicagoDowntown Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 06/02/2026 09:30:00 to Downtown Coach Station, Chicago (USA) arriving at 06/02/2026 16:30:00. 50 Economy ticket for £42 per person are available. Travel duration is 7h 0m
Cheapest Buses Friday
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FlixBus7h 0m009:30St. Louis, MOGateway Station16:30ChicagoDowntown Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 07/02/2026 09:30:00 to Downtown Coach Station, Chicago (USA) arriving at 07/02/2026 16:30:00. 50 Economy ticket for £26 per person are available. Travel duration is 7h 0m
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FlixBus6h 5m016:00St. Louis, MOGateway Station22:05ChicagoDowntown Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 07/02/2026 16:00:00 to Downtown Coach Station, Chicago (USA) arriving at 07/02/2026 22:05:00. 50 Economy ticket for £27 per person are available. Travel duration is 6h 5m
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FlixBus6h 15m023:30St. Louis, MOGateway Station05:45ChicagoDowntown Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 07/02/2026 23:30:00 to Downtown Coach Station, Chicago (USA) arriving at 08/02/2026 05:45:00. 50 Economy ticket for £28 per person are available. Travel duration is 6h 15m
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FlixBus6h 25m009:30St. Louis, MOGateway Station15:55Chicago95th Red Line Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 07/02/2026 09:30:00 to 95th Red Line Station, Chicago (USA) arriving at 07/02/2026 15:55:00. 50 Economy ticket for £29 per person are available. Travel duration is 6h 25m
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Frontier Airlines15h 23m020:22St. Louis Lambert AirportSt. Louis Lambert Airport11:45Chicago Midway AirportChicago Midway Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 07/02/2026 20:22:00 to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 08/02/2026 11:45:00. 50 Economy ticket for £70 per person are available. Travel duration is 15h 23m
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Frontier Airlines25h 57m020:22St. Louis Lambert AirportSt. Louis Lambert Airport22:19Chicago Midway AirportChicago Midway Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 07/02/2026 20:22:00 to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 08/02/2026 22:19:00. 50 Economy ticket for £82 per person are available. Travel duration is 25h 57m
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Frontier Airlines25h 52m020:22St. Louis Lambert AirportSt. Louis Lambert Airport22:14Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 07/02/2026 20:22:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 08/02/2026 22:14:00. 50 Economy ticket for £82 per person are available. Travel duration is 25h 52m
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Frontier Airlines17h 15m020:22St. Louis Lambert AirportSt. Louis Lambert Airport13:37Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 07/02/2026 20:22:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 08/02/2026 13:37:00. 50 Economy ticket for £91 per person are available. Travel duration is 17h 15m
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Frontier Airlines26h 10m017:42St. Louis Lambert AirportSt. Louis Lambert Airport19:52Chicago Midway AirportChicago Midway Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 07/02/2026 17:42:00 to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 08/02/2026 19:52:00. 50 Economy ticket for £125 per person are available. Travel duration is 26h 10m
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United Airlines1h 35m008:05St. Louis Lambert AirportSt. Louis Lambert Airport09:40Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 07/02/2026 08:05:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 07/02/2026 09:40:00. 50 Economy ticket for £221 per person are available. Travel duration is 1h 35m
Cheapest Buses Saturday
Cheapest Flights Saturday
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FlixBus7h 0m009:30St. Louis, MOGateway Station16:30ChicagoDowntown Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 08/02/2026 09:30:00 to Downtown Coach Station, Chicago (USA) arriving at 08/02/2026 16:30:00. 50 Economy ticket for £34 per person are available. Travel duration is 7h 0m
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FlixBus6h 25m009:30St. Louis, MOGateway Station15:55Chicago95th Red Line Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 08/02/2026 09:30:00 to 95th Red Line Station, Chicago (USA) arriving at 08/02/2026 15:55:00. 50 Economy ticket for £35 per person are available. Travel duration is 6h 25m
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FlixBus5h 50m023:30St. Louis, MOGateway Station05:20Chicago95th Red Line Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 08/02/2026 23:30:00 to 95th Red Line Station, Chicago (USA) arriving at 09/02/2026 05:20:00. 50 Economy ticket for £35 per person are available. Travel duration is 5h 50m
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Frontier Airlines10h 53m008:59St. Louis Lambert AirportSt. Louis Lambert Airport19:52Chicago Midway AirportChicago Midway Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 08/02/2026 08:59:00 to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 08/02/2026 19:52:00. 50 Economy ticket for £120 per person are available. Travel duration is 10h 53m
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Frontier Airlines26h 16m017:42St. Louis Lambert AirportSt. Louis Lambert Airport19:58Chicago Midway AirportChicago Midway Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 08/02/2026 17:42:00 to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 09/02/2026 19:58:00. 50 Economy ticket for £173 per person are available. Travel duration is 26h 16m
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Frontier Airlines10h 42m008:59St. Louis Lambert AirportSt. Louis Lambert Airport19:41Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 08/02/2026 08:59:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 08/02/2026 19:41:00. 50 Economy ticket for £173 per person are available. Travel duration is 10h 42m
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Frontier Airlines8h 53m008:59St. Louis Lambert AirportSt. Louis Lambert Airport17:52Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 08/02/2026 08:59:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 08/02/2026 17:52:00. 50 Economy ticket for £173 per person are available. Travel duration is 8h 53m
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Frontier Airlines16h 59m017:42St. Louis Lambert AirportSt. Louis Lambert Airport10:41Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 08/02/2026 17:42:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 09/02/2026 10:41:00. 50 Economy ticket for £173 per person are available. Travel duration is 16h 59m
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United Airlines1h 43m018:40St. Louis Lambert AirportSt. Louis Lambert Airport20:23Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 08/02/2026 18:40:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 08/02/2026 20:23:00. 50 Economy ticket for £220 per person are available. Travel duration is 1h 43m
Cheapest Buses Sunday
Cheapest Flights Sunday
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FlixBus6h 25m009:30St. Louis, MOGateway Station15:55Chicago95th Red Line Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 09/02/2026 09:30:00 to 95th Red Line Station, Chicago (USA) arriving at 09/02/2026 15:55:00. 50 Economy ticket for £30 per person are available. Travel duration is 6h 25m
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FlixBus5h 50m023:30St. Louis, MOGateway Station05:20Chicago95th Red Line Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 09/02/2026 23:30:00 to 95th Red Line Station, Chicago (USA) arriving at 10/02/2026 05:20:00. 50 Economy ticket for £30 per person are available. Travel duration is 5h 50m
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FlixBus7h 0m009:30St. Louis, MOGateway Station16:30ChicagoDowntown Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 09/02/2026 09:30:00 to Downtown Coach Station, Chicago (USA) arriving at 09/02/2026 16:30:00. 50 Economy ticket for £30 per person are available. Travel duration is 7h 0m
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FlixBus6h 15m023:30St. Louis, MOGateway Station05:45ChicagoDowntown Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 09/02/2026 23:30:00 to Downtown Coach Station, Chicago (USA) arriving at 10/02/2026 05:45:00. 50 Economy ticket for £30 per person are available. Travel duration is 6h 15m
Cheapest Buses Monday
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Greyhound US11h 40m002:00St. Louis, MOGateway Station13:40Chicago95th Red Line Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 10/02/2026 02:00:00 to 95th Red Line Station, Chicago (USA) arriving at 10/02/2026 13:40:00. 50 Economy ticket for £42 per person are available. Travel duration is 11h 40m
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FlixBus7h 35m016:00St. Louis, MOGateway Station23:35Chicago95th Red Line Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 10/02/2026 16:00:00 to 95th Red Line Station, Chicago (USA) arriving at 10/02/2026 23:35:00. 50 Economy ticket for £42 per person are available. Travel duration is 7h 35m
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Frontier Airlines24h 3m015:49St. Louis Lambert AirportSt. Louis Lambert Airport15:52Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 10/02/2026 15:49:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 11/02/2026 15:52:00. 50 Economy ticket for £68 per person are available. Travel duration is 24h 3m
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Frontier Airlines27h 52m015:49St. Louis Lambert AirportSt. Louis Lambert Airport19:41Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 10/02/2026 15:49:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 11/02/2026 19:41:00. 50 Economy ticket for £68 per person are available. Travel duration is 27h 52m
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Frontier Airlines29h 55m015:49St. Louis Lambert AirportSt. Louis Lambert Airport21:44Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 10/02/2026 15:49:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 11/02/2026 21:44:00. 50 Economy ticket for £68 per person are available. Travel duration is 29h 55m
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United Airlines14h 6m007:00St. Louis Lambert AirportSt. Louis Lambert Airport21:06Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 10/02/2026 07:00:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 10/02/2026 21:06:00. 50 Economy ticket for £237 per person are available. Travel duration is 14h 6m
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United Airlines22h 7m017:59St. Louis Lambert AirportSt. Louis Lambert Airport16:06Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 10/02/2026 17:59:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 11/02/2026 16:06:00. 50 Economy ticket for £237 per person are available. Travel duration is 22h 7m
Cheapest Buses Tuesday
Cheapest Flights Tuesday
What are the fastest trips from St. Louis, MO to Chicago?
You can get to Chicago from St. Louis, MO in just 1h 35m with a Flight from United Airlines. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
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United Airlines1h 35m013:15St. Louis Lambert AirportSt. Louis Lambert Airport14:50Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 04/02/2026 13:15:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 04/02/2026 14:50:00. 50 Economy ticket for £261 per person are available. Travel duration is 1h 35m
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United Airlines1h 37m011:20St. Louis Lambert AirportSt. Louis Lambert Airport12:57Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 04/02/2026 11:20:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 04/02/2026 12:57:00. 50 Economy ticket for £263 per person are available. Travel duration is 1h 37m
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Skyscanner1h 37m011:20St. Louis Lambert AirportSt. Louis Lambert Airport12:57Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Skyscanner goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 04/02/2026 11:20:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 04/02/2026 12:57:00. 50 Economy ticket for £263 per person are available. Travel duration is 1h 37m
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Frontier Airlines24h 10m017:42St. Louis Lambert AirportSt. Louis Lambert Airport17:52Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 04/02/2026 17:42:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 05/02/2026 17:52:00. 50 Economy ticket for £203 per person are available. Travel duration is 24h 10m
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Frontier Airlines25h 59m017:42St. Louis Lambert AirportSt. Louis Lambert Airport19:41Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 04/02/2026 17:42:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 05/02/2026 19:41:00. 50 Economy ticket for £203 per person are available. Travel duration is 25h 59m
Fastest Flights Wednesday
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Skyscanner1h 35m006:30St. Louis Lambert AirportSt. Louis Lambert Airport08:05Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Skyscanner goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 05/02/2026 06:30:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 05/02/2026 08:05:00. 50 Economy ticket for £152 per person are available. Travel duration is 1h 35m
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Skyscanner1h 35m008:05St. Louis Lambert AirportSt. Louis Lambert Airport09:40Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Skyscanner goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 05/02/2026 08:05:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 05/02/2026 09:40:00. 50 Economy ticket for £152 per person are available. Travel duration is 1h 35m
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United Airlines15h 59m007:00St. Louis Lambert AirportSt. Louis Lambert Airport22:59Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 05/02/2026 07:00:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 05/02/2026 22:59:00. 50 Economy ticket for £265 per person are available. Travel duration is 15h 59m
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Frontier Airlines16h 53m017:42St. Louis Lambert AirportSt. Louis Lambert Airport10:35Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 05/02/2026 17:42:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 06/02/2026 10:35:00. 50 Economy ticket for £66 per person are available. Travel duration is 16h 53m
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Frontier Airlines22h 28m022:01St. Louis Lambert AirportSt. Louis Lambert Airport20:29Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 05/02/2026 22:01:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 06/02/2026 20:29:00. 50 Economy ticket for £66 per person are available. Travel duration is 22h 28m
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Frontier Airlines26h 10m017:42St. Louis Lambert AirportSt. Louis Lambert Airport19:52Chicago Midway AirportChicago Midway Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 05/02/2026 17:42:00 to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 06/02/2026 19:52:00. 50 Economy ticket for £214 per person are available. Travel duration is 26h 10m
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FlixBus6h 15m023:30St. Louis, MOGateway Station05:45ChicagoDowntown Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 05/02/2026 23:30:00 to Downtown Coach Station, Chicago (USA) arriving at 06/02/2026 05:45:00. 50 Economy ticket for £27 per person are available. Travel duration is 6h 15m
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FlixBus7h 0m009:30St. Louis, MOGateway Station16:30ChicagoDowntown Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 05/02/2026 09:30:00 to Downtown Coach Station, Chicago (USA) arriving at 05/02/2026 16:30:00. 50 Economy ticket for £25 per person are available. Travel duration is 7h 0m
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Greyhound US12h 10m002:00St. Louis, MOGateway Station14:10ChicagoCanal & Van Buren0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 05/02/2026 02:00:00 to Canal & Van Buren, Chicago (USA) arriving at 05/02/2026 14:10:00. 50 Economy ticket for £27 per person are available. Travel duration is 12h 10m
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Greyhound US12h 10m002:00St. Louis, MOGateway Station14:10ChicagoUnion Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 05/02/2026 02:00:00 to Union Station, Chicago (USA) arriving at 05/02/2026 14:10:00. 50 Economy ticket for £31 per person are available. Travel duration is 12h 10m
Fastest Flights Thursday
Fastest Buses Thursday
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FlixBus5h 50m023:30St. Louis, MOGateway Station05:20Chicago95th Red Line Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 06/02/2026 23:30:00 to 95th Red Line Station, Chicago (USA) arriving at 07/02/2026 05:20:00. 50 Economy ticket for £35 per person are available. Travel duration is 5h 50m
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FlixBus6h 15m023:30St. Louis, MOGateway Station05:45ChicagoDowntown Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 06/02/2026 23:30:00 to Downtown Coach Station, Chicago (USA) arriving at 07/02/2026 05:45:00. 50 Economy ticket for £34 per person are available. Travel duration is 6h 15m
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FlixBus7h 0m009:30St. Louis, MOGateway Station16:30ChicagoDowntown Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 06/02/2026 09:30:00 to Downtown Coach Station, Chicago (USA) arriving at 06/02/2026 16:30:00. 50 Economy ticket for £42 per person are available. Travel duration is 7h 0m
Fastest Buses Friday
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United Airlines1h 35m008:05St. Louis Lambert AirportSt. Louis Lambert Airport09:40Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 07/02/2026 08:05:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 07/02/2026 09:40:00. 50 Economy ticket for £221 per person are available. Travel duration is 1h 35m
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United Airlines1h 35m009:57St. Louis Lambert AirportSt. Louis Lambert Airport11:32Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 07/02/2026 09:57:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 07/02/2026 11:32:00. 50 Economy ticket for £221 per person are available. Travel duration is 1h 35m
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Frontier Airlines15h 23m020:22St. Louis Lambert AirportSt. Louis Lambert Airport11:45Chicago Midway AirportChicago Midway Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 07/02/2026 20:22:00 to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 08/02/2026 11:45:00. 50 Economy ticket for £70 per person are available. Travel duration is 15h 23m
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Frontier Airlines17h 15m020:22St. Louis Lambert AirportSt. Louis Lambert Airport13:37Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 07/02/2026 20:22:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 08/02/2026 13:37:00. 50 Economy ticket for £91 per person are available. Travel duration is 17h 15m
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Alaska Airlines20h 19m018:19St. Louis Lambert AirportSt. Louis Lambert Airport14:38Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Alaska Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 07/02/2026 18:19:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 08/02/2026 14:38:00. 50 Economy ticket for £367 per person are available. Travel duration is 20h 19m
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Frontier Airlines25h 52m020:22St. Louis Lambert AirportSt. Louis Lambert Airport22:14Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 07/02/2026 20:22:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 08/02/2026 22:14:00. 50 Economy ticket for £82 per person are available. Travel duration is 25h 52m
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FlixBus6h 5m016:00St. Louis, MOGateway Station22:05ChicagoDowntown Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 07/02/2026 16:00:00 to Downtown Coach Station, Chicago (USA) arriving at 07/02/2026 22:05:00. 50 Economy ticket for £27 per person are available. Travel duration is 6h 5m
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FlixBus6h 15m023:30St. Louis, MOGateway Station05:45ChicagoDowntown Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 07/02/2026 23:30:00 to Downtown Coach Station, Chicago (USA) arriving at 08/02/2026 05:45:00. 50 Economy ticket for £28 per person are available. Travel duration is 6h 15m
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FlixBus6h 25m009:30St. Louis, MOGateway Station15:55Chicago95th Red Line Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 07/02/2026 09:30:00 to 95th Red Line Station, Chicago (USA) arriving at 07/02/2026 15:55:00. 50 Economy ticket for £29 per person are available. Travel duration is 6h 25m
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FlixBus7h 0m009:30St. Louis, MOGateway Station16:30ChicagoDowntown Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 07/02/2026 09:30:00 to Downtown Coach Station, Chicago (USA) arriving at 07/02/2026 16:30:00. 50 Economy ticket for £26 per person are available. Travel duration is 7h 0m
Fastest Flights Saturday
Fastest Buses Saturday
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United Airlines1h 35m006:30St. Louis Lambert AirportSt. Louis Lambert Airport08:05Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 08/02/2026 06:30:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 08/02/2026 08:05:00. 50 Economy ticket for £221 per person are available. Travel duration is 1h 35m
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United Airlines1h 43m018:40St. Louis Lambert AirportSt. Louis Lambert Airport20:23Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 08/02/2026 18:40:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 08/02/2026 20:23:00. 50 Economy ticket for £220 per person are available. Travel duration is 1h 43m
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Frontier Airlines8h 53m008:59St. Louis Lambert AirportSt. Louis Lambert Airport17:52Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 08/02/2026 08:59:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 08/02/2026 17:52:00. 50 Economy ticket for £173 per person are available. Travel duration is 8h 53m
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Frontier Airlines10h 42m008:59St. Louis Lambert AirportSt. Louis Lambert Airport19:41Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 08/02/2026 08:59:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 08/02/2026 19:41:00. 50 Economy ticket for £173 per person are available. Travel duration is 10h 42m
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Frontier Airlines10h 53m008:59St. Louis Lambert AirportSt. Louis Lambert Airport19:52Chicago Midway AirportChicago Midway Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 08/02/2026 08:59:00 to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 08/02/2026 19:52:00. 50 Economy ticket for £120 per person are available. Travel duration is 10h 53m
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Frontier Airlines16h 59m017:42St. Louis Lambert AirportSt. Louis Lambert Airport10:41Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 08/02/2026 17:42:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 09/02/2026 10:41:00. 50 Economy ticket for £173 per person are available. Travel duration is 16h 59m
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FlixBus5h 50m023:30St. Louis, MOGateway Station05:20Chicago95th Red Line Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 08/02/2026 23:30:00 to 95th Red Line Station, Chicago (USA) arriving at 09/02/2026 05:20:00. 50 Economy ticket for £35 per person are available. Travel duration is 5h 50m
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FlixBus6h 25m009:30St. Louis, MOGateway Station15:55Chicago95th Red Line Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 08/02/2026 09:30:00 to 95th Red Line Station, Chicago (USA) arriving at 08/02/2026 15:55:00. 50 Economy ticket for £35 per person are available. Travel duration is 6h 25m
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FlixBus7h 0m009:30St. Louis, MOGateway Station16:30ChicagoDowntown Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 08/02/2026 09:30:00 to Downtown Coach Station, Chicago (USA) arriving at 08/02/2026 16:30:00. 50 Economy ticket for £34 per person are available. Travel duration is 7h 0m
Fastest Flights Sunday
Fastest Buses Sunday
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FlixBus5h 50m023:30St. Louis, MOGateway Station05:20Chicago95th Red Line Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 09/02/2026 23:30:00 to 95th Red Line Station, Chicago (USA) arriving at 10/02/2026 05:20:00. 50 Economy ticket for £30 per person are available. Travel duration is 5h 50m
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FlixBus6h 15m023:30St. Louis, MOGateway Station05:45ChicagoDowntown Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 09/02/2026 23:30:00 to Downtown Coach Station, Chicago (USA) arriving at 10/02/2026 05:45:00. 50 Economy ticket for £30 per person are available. Travel duration is 6h 15m
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FlixBus6h 25m009:30St. Louis, MOGateway Station15:55Chicago95th Red Line Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 09/02/2026 09:30:00 to 95th Red Line Station, Chicago (USA) arriving at 09/02/2026 15:55:00. 50 Economy ticket for £30 per person are available. Travel duration is 6h 25m
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FlixBus7h 0m009:30St. Louis, MOGateway Station16:30ChicagoDowntown Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 09/02/2026 09:30:00 to Downtown Coach Station, Chicago (USA) arriving at 09/02/2026 16:30:00. 50 Economy ticket for £30 per person are available. Travel duration is 7h 0m
Fastest Buses Monday
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FlixBus7h 35m016:00St. Louis, MOGateway Station23:35Chicago95th Red Line Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 10/02/2026 16:00:00 to 95th Red Line Station, Chicago (USA) arriving at 10/02/2026 23:35:00. 50 Economy ticket for £42 per person are available. Travel duration is 7h 35m
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Greyhound US11h 40m002:00St. Louis, MOGateway Station13:40Chicago95th Red Line Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 10/02/2026 02:00:00 to 95th Red Line Station, Chicago (USA) arriving at 10/02/2026 13:40:00. 50 Economy ticket for £42 per person are available. Travel duration is 11h 40m
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United Airlines14h 6m007:00St. Louis Lambert AirportSt. Louis Lambert Airport21:06Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 10/02/2026 07:00:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 10/02/2026 21:06:00. 50 Economy ticket for £237 per person are available. Travel duration is 14h 6m
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United Airlines22h 7m017:59St. Louis Lambert AirportSt. Louis Lambert Airport16:06Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 10/02/2026 17:59:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 11/02/2026 16:06:00. 50 Economy ticket for £237 per person are available. Travel duration is 22h 7m
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Frontier Airlines24h 3m015:49St. Louis Lambert AirportSt. Louis Lambert Airport15:52Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 10/02/2026 15:49:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 11/02/2026 15:52:00. 50 Economy ticket for £68 per person are available. Travel duration is 24h 3m
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Frontier Airlines27h 52m015:49St. Louis Lambert AirportSt. Louis Lambert Airport19:41Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 10/02/2026 15:49:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 11/02/2026 19:41:00. 50 Economy ticket for £68 per person are available. Travel duration is 27h 52m
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Frontier Airlines29h 55m015:49St. Louis Lambert AirportSt. Louis Lambert Airport21:44Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 10/02/2026 15:49:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 11/02/2026 21:44:00. 50 Economy ticket for £68 per person are available. Travel duration is 29h 55m
Fastest Buses Tuesday
Fastest Flights Tuesday
Here you will find all operators and timetables for a
Bus from St. Louis, MO to Chicago
What are the most popular stations in St. Louis, MO and Chicago?
In St. Louis, MO, you will usually depart from Gateway Station, Lindbergh @ Hackberry NB Bus Stop or Skinker Boulevard, while in Chicago you will be arriving at California & 35th Street Coach Stop, Downtown Coach Station or 95th Red Line Station, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Chicago from St. Louis, MO? With 8 connections between 2 Flight and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between St. Louis, MO and Chicago, you can pay as low as £25 with a Bus from FlixBus.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from United Airlines: you will get to Chicago in just 1h 35m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting St. Louis, MO and Chicago are FlixBus, Frontier Airlines and United Airlines, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in St. Louis, MO and Chicago is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Sauget, IL or to Cicero, IL, and look at flights from St. Louis Lambert Airport, and landing at Chicago Midway Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from St. Louis, MO to Chicago?
The most popular companies between St. Louis, MO and Chicago, are FlixBus, Frontier Airlines and United Airlines. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: FlixBus and Greyhound US
Airlines: Frontier Airlines, United Airlines, Skyscanner and 1 more.
All you need to know when you travel from St. Louis, MO to Chicago
Check all information on comfort and services on all modes of transports from St. Louis, MO to Chicago. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from St. Louis, MO to Chicago
How can I reach Chicago from St. Louis, MO?
Every day, there are on average 8 connections between Flight and Bus, with which you can get to Chicago from St. Louis, MO.
How far is Chicago from St. Louis, MO?
The distance between St. Louis, MO and Chicago is 422.1 km.
What is the most ecofriendly mode of transport between St. Louis, MO and Chicago?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 11 kgs of CO2, a train 15 kgs, a car 72 kgs, and a flight 104 kgs.
What is the cheapest mode of transport from St. Louis, MO to Chicago?
You can get to Chicago with just £25 by taking a Bus from FlixBus.
What is the fastest way to get from St. Louis, MO to Chicago?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Chicago in just 1h 35m with a Flight from United Airlines.
More routes to St. Louis, MO and to Chicago
Looking for more options? Here you can see the most popular routes to St. Louis, MO and to Chicago. Simply click on a connection, and you’ll find all the details about the route!
- Trips to St. Louis, MO
- Atlanta, GA to St. Louis, MO
- Ciudad Juárez to St. Louis, MO
- Dallas to St. Louis, MO
- Houston to St. Louis, MO
- Mexico City to St. Louis, MO
- Monterrey, NL to St. Louis, MO
- Trips to Chicago
- Aguascalientes to Chicago
- Atlanta, GA to Chicago
- Bloomington, IN to Chicago
- Cincinnati to Chicago
- Ciudad Juárez to Chicago
- Dallas to Chicago
- El Paso, TX to Chicago
- Houston to Chicago
- Laredo, TX to Chicago
- Little Rock, AR to Chicago
- Los Angeles to Chicago
- McAllen, TX to Chicago
- Memphis to Chicago
- Mexico City to Chicago
- New York to Chicago
- Niagara Falls, ON to Chicago
- Pearson Toronto Airport to Chicago
- Philadelphia, PA to Chicago
- Phoenix, AZ to Chicago
- San Antonio, TX to Chicago
- Tampa to Chicago
- Toronto, ON to Chicago
