What is the best way to travel from Houston to St. Louis, MO?
Looking for a trip? Check and compare all the available Buses and Flights to St. Louis, MO from Houston. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 4 available companies to find your perfect trip!
What is the cheapest way to reach St. Louis, MO from Houston?
You can reach St. Louis, MO with just £76 by taking a Bus from FlixBus, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
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FlixBus22h 15m008:55HoustonUptown/Upper Kirby07:10St. Louis, MOGateway Station0EconomyA Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 26/06/2026 08:55:00 to Gateway Station, St. Louis, MO (USA) arriving at 27/06/2026 07:10:00. 50 Economy ticket for £76 per person are available. Travel duration is 22h 15m
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FlixBus26h 55m019:50HoustonUptown/Upper Kirby22:45St. Louis, MOGateway Station0EconomyA Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 26/06/2026 19:50:00 to Gateway Station, St. Louis, MO (USA) arriving at 27/06/2026 22:45:00. 50 Economy ticket for £77 per person are available. Travel duration is 26h 55m
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Greyhound US23h 10m013:45HoustonHarrisburg Blvd Station12:55St. Louis, MOGateway Station0EconomyA Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 26/06/2026 13:45:00 to Gateway Station, St. Louis, MO (USA) arriving at 27/06/2026 12:55:00. 50 Economy ticket for £82 per person are available. Travel duration is 23h 10m
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Greyhound US25h 0m022:00HoustonHarrisburg Blvd Station23:00St. Louis, MOGateway Station0EconomyA Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 26/06/2026 22:00:00 to Gateway Station, St. Louis, MO (USA) arriving at 27/06/2026 23:00:00. 50 Economy ticket for £82 per person are available. Travel duration is 25h 0m
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Valley Transit30h 20m006:35HoustonSW Agencia Autobuses12:55St. Louis, MOGateway Station0EconomyA Bus from Valley Transit goes from SW Agencia Autobuses, Houston (USA) at 26/06/2026 06:35:00 to Gateway Station, St. Louis, MO (USA) arriving at 27/06/2026 12:55:00. 50 Economy ticket for £84 per person are available. Travel duration is 30h 20m
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Frontier Airlines27h 7m005:45George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport08:52St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Frontier Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 26/06/2026 05:45:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 27/06/2026 08:52:00. 50 Economy ticket for £114 per person are available. Travel duration is 27h 7m
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Frontier Airlines11h 57m020:55George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport08:52St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Frontier Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 26/06/2026 20:55:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 27/06/2026 08:52:00. 50 Economy ticket for £114 per person are available. Travel duration is 11h 57m
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United Airlines2h 7m008:00George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport10:07St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from United Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 26/06/2026 08:00:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 26/06/2026 10:07:00. 50 Economy ticket for £184 per person are available. Travel duration is 2h 7m
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United Airlines2h 16m012:00George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport14:16St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from United Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 26/06/2026 12:00:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 26/06/2026 14:16:00. 50 Economy ticket for £184 per person are available. Travel duration is 2h 16m
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Alaska Airlines22h 18m018:19George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport16:37St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Alaska Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 26/06/2026 18:19:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 27/06/2026 16:37:00. 50 Economy ticket for £469 per person are available. Travel duration is 22h 18m
Cheapest Buses Friday
Cheapest Flights Friday
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Greyhound US20h 55m001:50HoustonHarrisburg Blvd Station22:45St. Louis, MOGateway Station0EconomyA Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 27/06/2026 01:50:00 to Gateway Station, St. Louis, MO (USA) arriving at 27/06/2026 22:45:00. 50 Economy ticket for £84 per person are available. Travel duration is 20h 55m
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Greyhound US23h 10m013:45HoustonHarrisburg Blvd Station12:55St. Louis, MOGateway Station0EconomyA Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 27/06/2026 13:45:00 to Gateway Station, St. Louis, MO (USA) arriving at 28/06/2026 12:55:00. 50 Economy ticket for £84 per person are available. Travel duration is 23h 10m
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Valley Transit30h 20m006:35HoustonSW Agencia Autobuses12:55St. Louis, MOGateway Station0EconomyA Bus from Valley Transit goes from SW Agencia Autobuses, Houston (USA) at 27/06/2026 06:35:00 to Gateway Station, St. Louis, MO (USA) arriving at 28/06/2026 12:55:00. 50 Economy ticket for £84 per person are available. Travel duration is 30h 20m
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FlixBus21h 10m010:00HoustonDowntown Houston07:10St. Louis, MOGateway Station0EconomyA Bus from FlixBus goes from Downtown Houston, Houston (USA) at 27/06/2026 10:00:00 to Gateway Station, St. Louis, MO (USA) arriving at 28/06/2026 07:10:00. 50 Economy ticket for £85 per person are available. Travel duration is 21h 10m
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FlixBus23h 40m013:15HoustonDowntown Houston12:55St. Louis, MOGateway Station0EconomyA Bus from FlixBus goes from Downtown Houston, Houston (USA) at 27/06/2026 13:15:00 to Gateway Station, St. Louis, MO (USA) arriving at 28/06/2026 12:55:00. 50 Economy ticket for £85 per person are available. Travel duration is 23h 40m
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Frontier Airlines12h 23m006:30George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport18:53St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Frontier Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 27/06/2026 06:30:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 27/06/2026 18:53:00. 50 Economy ticket for £99 per person are available. Travel duration is 12h 23m
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Frontier Airlines28h 25m019:24George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport23:49St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Frontier Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 27/06/2026 19:24:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 28/06/2026 23:49:00. 50 Economy ticket for £99 per person are available. Travel duration is 28h 25m
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United Airlines2h 7m008:00George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport10:07St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from United Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 27/06/2026 08:00:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 27/06/2026 10:07:00. 50 Economy ticket for £155 per person are available. Travel duration is 2h 7m
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United Airlines2h 14m018:28George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport20:42St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from United Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 27/06/2026 18:28:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 27/06/2026 20:42:00. 50 Economy ticket for £155 per person are available. Travel duration is 2h 14m
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Skyscanner2h 7m008:00George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport10:07St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Skyscanner goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 27/06/2026 08:00:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 27/06/2026 10:07:00. 50 Economy ticket for £155 per person are available. Travel duration is 2h 7m
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Frontier Airlines34h 55m021:58George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport08:53MidAmerica St. Louis AirportMidAmerica St. Louis Airport0EconomyA Flight from Frontier Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 27/06/2026 21:58:00 to MidAmerica St. Louis Airport, MidAmerica St. Louis Airport (USA) arriving at 29/06/2026 08:53:00. 50 Economy ticket for £165 per person are available. Travel duration is 34h 55m
Cheapest Buses Saturday
Cheapest Flights Saturday
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Greyhound US23h 10m013:45HoustonHarrisburg Blvd Station12:55St. Louis, MOGateway Station0EconomyA Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 28/06/2026 13:45:00 to Gateway Station, St. Louis, MO (USA) arriving at 29/06/2026 12:55:00. 50 Economy ticket for £105 per person are available. Travel duration is 23h 10m
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FlixBus23h 40m013:15HoustonDowntown Houston12:55St. Louis, MOGateway Station0EconomyA Bus from FlixBus goes from Downtown Houston, Houston (USA) at 28/06/2026 13:15:00 to Gateway Station, St. Louis, MO (USA) arriving at 29/06/2026 12:55:00. 50 Economy ticket for £105 per person are available. Travel duration is 23h 40m
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Valley Transit30h 20m006:35HoustonSW Agencia Autobuses12:55St. Louis, MOGateway Station0EconomyA Bus from Valley Transit goes from SW Agencia Autobuses, Houston (USA) at 28/06/2026 06:35:00 to Gateway Station, St. Louis, MO (USA) arriving at 29/06/2026 12:55:00. 50 Economy ticket for £105 per person are available. Travel duration is 30h 20m
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FlixBus21h 10m010:00HoustonDowntown Houston07:10St. Louis, MOGateway Station0EconomyA Bus from FlixBus goes from Downtown Houston, Houston (USA) at 28/06/2026 10:00:00 to Gateway Station, St. Louis, MO (USA) arriving at 29/06/2026 07:10:00. 50 Economy ticket for £112 per person are available. Travel duration is 21h 10m
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Greyhound US22h 55m008:15HoustonHarrisburg Blvd Station07:10St. Louis, MOGateway Station0EconomyA Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 28/06/2026 08:15:00 to Gateway Station, St. Louis, MO (USA) arriving at 29/06/2026 07:10:00. 50 Economy ticket for £114 per person are available. Travel duration is 22h 55m
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Frontier Airlines11h 0m006:30George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport17:30St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Frontier Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 28/06/2026 06:30:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 28/06/2026 17:30:00. 50 Economy ticket for £116 per person are available. Travel duration is 11h 0m
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Skyscanner2h 7m008:00George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport10:07St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Skyscanner goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 28/06/2026 08:00:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 28/06/2026 10:07:00. 50 Economy ticket for £154 per person are available. Travel duration is 2h 7m
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Skyscanner2h 14m018:28George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport20:42St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Skyscanner goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 28/06/2026 18:28:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 28/06/2026 20:42:00. 50 Economy ticket for £154 per person are available. Travel duration is 2h 14m
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United Airlines2h 7m008:00George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport10:07St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from United Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 28/06/2026 08:00:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 28/06/2026 10:07:00. 50 Economy ticket for £155 per person are available. Travel duration is 2h 7m
Cheapest Buses Sunday
Cheapest Flights Sunday
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Greyhound US20h 55m001:50HoustonHarrisburg Blvd Station22:45St. Louis, MOGateway Station0EconomyA Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 02/07/2026 01:50:00 to Gateway Station, St. Louis, MO (USA) arriving at 02/07/2026 22:45:00. 50 Economy ticket for £93 per person are available. Travel duration is 20h 55m
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FlixBus25h 45m011:10HoustonDowntown Houston12:55St. Louis, MOGateway Station0EconomyA Bus from FlixBus goes from Downtown Houston, Houston (USA) at 02/07/2026 11:10:00 to Gateway Station, St. Louis, MO (USA) arriving at 03/07/2026 12:55:00. 50 Economy ticket for £93 per person are available. Travel duration is 25h 45m
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Valley Transit30h 20m006:35HoustonSW Agencia Autobuses12:55St. Louis, MOGateway Station0EconomyA Bus from Valley Transit goes from SW Agencia Autobuses, Houston (USA) at 02/07/2026 06:35:00 to Gateway Station, St. Louis, MO (USA) arriving at 03/07/2026 12:55:00. 50 Economy ticket for £94 per person are available. Travel duration is 30h 20m
Cheapest Buses Thursday
What are the fastest trips from Houston to St. Louis, MO?
You can get to St. Louis, MO from Houston in just 2h 7m with a Flight from United Airlines. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
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United Airlines2h 7m008:00George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport10:07St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from United Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 26/06/2026 08:00:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 26/06/2026 10:07:00. 50 Economy ticket for £184 per person are available. Travel duration is 2h 7m
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United Airlines2h 16m012:00George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport14:16St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from United Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 26/06/2026 12:00:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 26/06/2026 14:16:00. 50 Economy ticket for £184 per person are available. Travel duration is 2h 16m
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Frontier Airlines11h 57m020:55George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport08:52St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Frontier Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 26/06/2026 20:55:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 27/06/2026 08:52:00. 50 Economy ticket for £114 per person are available. Travel duration is 11h 57m
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Alaska Airlines22h 18m018:19George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport16:37St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Alaska Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 26/06/2026 18:19:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 27/06/2026 16:37:00. 50 Economy ticket for £469 per person are available. Travel duration is 22h 18m
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Frontier Airlines27h 7m005:45George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport08:52St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Frontier Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 26/06/2026 05:45:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 27/06/2026 08:52:00. 50 Economy ticket for £114 per person are available. Travel duration is 27h 7m
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FlixBus22h 15m008:55HoustonUptown/Upper Kirby07:10St. Louis, MOGateway Station0EconomyA Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 26/06/2026 08:55:00 to Gateway Station, St. Louis, MO (USA) arriving at 27/06/2026 07:10:00. 50 Economy ticket for £76 per person are available. Travel duration is 22h 15m
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Greyhound US23h 10m013:45HoustonHarrisburg Blvd Station12:55St. Louis, MOGateway Station0EconomyA Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 26/06/2026 13:45:00 to Gateway Station, St. Louis, MO (USA) arriving at 27/06/2026 12:55:00. 50 Economy ticket for £82 per person are available. Travel duration is 23h 10m
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Greyhound US25h 0m022:00HoustonHarrisburg Blvd Station23:00St. Louis, MOGateway Station0EconomyA Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 26/06/2026 22:00:00 to Gateway Station, St. Louis, MO (USA) arriving at 27/06/2026 23:00:00. 50 Economy ticket for £82 per person are available. Travel duration is 25h 0m
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FlixBus26h 55m019:50HoustonUptown/Upper Kirby22:45St. Louis, MOGateway Station0EconomyA Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 26/06/2026 19:50:00 to Gateway Station, St. Louis, MO (USA) arriving at 27/06/2026 22:45:00. 50 Economy ticket for £77 per person are available. Travel duration is 26h 55m
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Valley Transit30h 20m006:35HoustonSW Agencia Autobuses12:55St. Louis, MOGateway Station0EconomyA Bus from Valley Transit goes from SW Agencia Autobuses, Houston (USA) at 26/06/2026 06:35:00 to Gateway Station, St. Louis, MO (USA) arriving at 27/06/2026 12:55:00. 50 Economy ticket for £84 per person are available. Travel duration is 30h 20m
Fastest Flights Friday
Fastest Buses Friday
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United Airlines2h 7m008:00George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport10:07St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from United Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 27/06/2026 08:00:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 27/06/2026 10:07:00. 50 Economy ticket for £155 per person are available. Travel duration is 2h 7m
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Skyscanner2h 7m008:00George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport10:07St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Skyscanner goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 27/06/2026 08:00:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 27/06/2026 10:07:00. 50 Economy ticket for £155 per person are available. Travel duration is 2h 7m
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United Airlines2h 14m018:28George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport20:42St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from United Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 27/06/2026 18:28:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 27/06/2026 20:42:00. 50 Economy ticket for £155 per person are available. Travel duration is 2h 14m
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Frontier Airlines12h 23m006:30George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport18:53St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Frontier Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 27/06/2026 06:30:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 27/06/2026 18:53:00. 50 Economy ticket for £99 per person are available. Travel duration is 12h 23m
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JetBlue Airways26h 8m018:20George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport20:28MidAmerica St. Louis AirportMidAmerica St. Louis Airport0EconomyA Flight from JetBlue Airways goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 27/06/2026 18:20:00 to MidAmerica St. Louis Airport, MidAmerica St. Louis Airport (USA) arriving at 28/06/2026 20:28:00. 50 Economy ticket for £336 per person are available. Travel duration is 26h 8m
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Frontier Airlines28h 25m019:24George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport23:49St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Frontier Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 27/06/2026 19:24:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 28/06/2026 23:49:00. 50 Economy ticket for £99 per person are available. Travel duration is 28h 25m
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Greyhound US20h 55m001:50HoustonHarrisburg Blvd Station22:45St. Louis, MOGateway Station0EconomyA Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 27/06/2026 01:50:00 to Gateway Station, St. Louis, MO (USA) arriving at 27/06/2026 22:45:00. 50 Economy ticket for £84 per person are available. Travel duration is 20h 55m
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FlixBus21h 10m010:00HoustonDowntown Houston07:10St. Louis, MOGateway Station0EconomyA Bus from FlixBus goes from Downtown Houston, Houston (USA) at 27/06/2026 10:00:00 to Gateway Station, St. Louis, MO (USA) arriving at 28/06/2026 07:10:00. 50 Economy ticket for £85 per person are available. Travel duration is 21h 10m
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Greyhound US23h 10m013:45HoustonHarrisburg Blvd Station12:55St. Louis, MOGateway Station0EconomyA Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 27/06/2026 13:45:00 to Gateway Station, St. Louis, MO (USA) arriving at 28/06/2026 12:55:00. 50 Economy ticket for £84 per person are available. Travel duration is 23h 10m
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FlixBus23h 40m013:15HoustonDowntown Houston12:55St. Louis, MOGateway Station0EconomyA Bus from FlixBus goes from Downtown Houston, Houston (USA) at 27/06/2026 13:15:00 to Gateway Station, St. Louis, MO (USA) arriving at 28/06/2026 12:55:00. 50 Economy ticket for £85 per person are available. Travel duration is 23h 40m
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Valley Transit30h 20m006:35HoustonSW Agencia Autobuses12:55St. Louis, MOGateway Station0EconomyA Bus from Valley Transit goes from SW Agencia Autobuses, Houston (USA) at 27/06/2026 06:35:00 to Gateway Station, St. Louis, MO (USA) arriving at 28/06/2026 12:55:00. 50 Economy ticket for £84 per person are available. Travel duration is 30h 20m
Fastest Flights Saturday
Fastest Buses Saturday
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Skyscanner2h 7m008:00George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport10:07St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Skyscanner goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 28/06/2026 08:00:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 28/06/2026 10:07:00. 50 Economy ticket for £154 per person are available. Travel duration is 2h 7m
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United Airlines2h 7m008:00George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport10:07St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from United Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 28/06/2026 08:00:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 28/06/2026 10:07:00. 50 Economy ticket for £155 per person are available. Travel duration is 2h 7m
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Skyscanner2h 14m018:28George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport20:42St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Skyscanner goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 28/06/2026 18:28:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 28/06/2026 20:42:00. 50 Economy ticket for £154 per person are available. Travel duration is 2h 14m
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Frontier Airlines11h 0m006:30George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport17:30St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Frontier Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 28/06/2026 06:30:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 28/06/2026 17:30:00. 50 Economy ticket for £116 per person are available. Travel duration is 11h 0m
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FlixBus21h 10m010:00HoustonDowntown Houston07:10St. Louis, MOGateway Station0EconomyA Bus from FlixBus goes from Downtown Houston, Houston (USA) at 28/06/2026 10:00:00 to Gateway Station, St. Louis, MO (USA) arriving at 29/06/2026 07:10:00. 50 Economy ticket for £112 per person are available. Travel duration is 21h 10m
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Greyhound US22h 55m008:15HoustonHarrisburg Blvd Station07:10St. Louis, MOGateway Station0EconomyA Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 28/06/2026 08:15:00 to Gateway Station, St. Louis, MO (USA) arriving at 29/06/2026 07:10:00. 50 Economy ticket for £114 per person are available. Travel duration is 22h 55m
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Greyhound US23h 10m013:45HoustonHarrisburg Blvd Station12:55St. Louis, MOGateway Station0EconomyA Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 28/06/2026 13:45:00 to Gateway Station, St. Louis, MO (USA) arriving at 29/06/2026 12:55:00. 50 Economy ticket for £105 per person are available. Travel duration is 23h 10m
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FlixBus23h 40m013:15HoustonDowntown Houston12:55St. Louis, MOGateway Station0EconomyA Bus from FlixBus goes from Downtown Houston, Houston (USA) at 28/06/2026 13:15:00 to Gateway Station, St. Louis, MO (USA) arriving at 29/06/2026 12:55:00. 50 Economy ticket for £105 per person are available. Travel duration is 23h 40m
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Valley Transit30h 20m006:35HoustonSW Agencia Autobuses12:55St. Louis, MOGateway Station0EconomyA Bus from Valley Transit goes from SW Agencia Autobuses, Houston (USA) at 28/06/2026 06:35:00 to Gateway Station, St. Louis, MO (USA) arriving at 29/06/2026 12:55:00. 50 Economy ticket for £105 per person are available. Travel duration is 30h 20m
Fastest Flights Sunday
Fastest Buses Sunday
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Greyhound US20h 55m001:50HoustonHarrisburg Blvd Station22:45St. Louis, MOGateway Station0EconomyA Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 02/07/2026 01:50:00 to Gateway Station, St. Louis, MO (USA) arriving at 02/07/2026 22:45:00. 50 Economy ticket for £93 per person are available. Travel duration is 20h 55m
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FlixBus25h 45m011:10HoustonDowntown Houston12:55St. Louis, MOGateway Station0EconomyA Bus from FlixBus goes from Downtown Houston, Houston (USA) at 02/07/2026 11:10:00 to Gateway Station, St. Louis, MO (USA) arriving at 03/07/2026 12:55:00. 50 Economy ticket for £93 per person are available. Travel duration is 25h 45m
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Valley Transit30h 20m006:35HoustonSW Agencia Autobuses12:55St. Louis, MOGateway Station0EconomyA Bus from Valley Transit goes from SW Agencia Autobuses, Houston (USA) at 02/07/2026 06:35:00 to Gateway Station, St. Louis, MO (USA) arriving at 03/07/2026 12:55:00. 50 Economy ticket for £94 per person are available. Travel duration is 30h 20m
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Here you will find all operators and timetables for a
Bus from Houston to St. Louis, MO
What are the most popular stations in Houston and St. Louis, MO?
In Houston, you will usually depart from Hillcroft METRO Park and Ride Coach Station, Lockwood or Main St & Airline Dr, while in St. Louis, MO you will be arriving at Gateway Station, Lindbergh @ Hackberry NB Bus Stop or Skinker Boulevard, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to St. Louis, MO from Houston? With 9 connections between 4 Flight and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Houston and St. Louis, MO, you can pay as low as £76 with a Bus from FlixBus.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from United Airlines: you will get to St. Louis, MO in just 2h 7m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Houston and St. Louis, MO are Frontier Airlines, FlixBus and Greyhound US, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Houston and St. Louis, MO is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from West University Place, TX or to Sauget, IL, and look at flights from William P. Hobby Airport, and landing at St. Louis Lambert Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Houston to St. Louis, MO?
The most popular companies between Houston and St. Louis, MO, are Frontier Airlines, FlixBus and Greyhound US. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: FlixBus, Greyhound US and Valley Transit
Airlines: Frontier Airlines, United Airlines, Skyscanner and 2 more.
All you need to know when you travel from Houston to St. Louis, MO
Check all information on comfort and services on all modes of transports from Houston to St. Louis, MO. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Houston to St. Louis, MO
How can I reach St. Louis, MO from Houston?
Every day, there are on average 9 connections between Flight and Bus, with which you can get to St. Louis, MO from Houston.
How far is St. Louis, MO from Houston?
The distance between Houston and St. Louis, MO is 1,094.8 km.
What is the most ecofriendly mode of transport between Houston and St. Louis, MO?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 30 kgs of CO2, a train 38 kgs, a car 186 kgs, and a flight 269 kgs.
What is the cheapest mode of transport from Houston to St. Louis, MO?
You can get to St. Louis, MO with just £76 by taking a Bus from FlixBus.
What is the fastest way to get from Houston to St. Louis, MO?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to St. Louis, MO in just 2h 7m with a Flight from United Airlines.
More routes to Houston and to St. Louis, MO
Looking for more options? Here you can see the most popular routes to Houston and to St. Louis, MO. Simply click on a connection, and you’ll find all the details about the route!
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