What is the best way to travel from Houston to St. Louis, MO?
Looking for a trip? Check and compare all the available Buses and Flights to St. Louis, MO from Houston. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 5 available companies to find your perfect trip!
What is the cheapest way to reach St. Louis, MO from Houston?
You can reach St. Louis, MO with just £51 by taking a Flight from Frontier Airlines, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
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Frontier Airlines24h 40m006:10George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport06:50St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Frontier Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 21/04/2026 06:10:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 22/04/2026 06:50:00. 50 Economy ticket for £51 per person are available. Travel duration is 24h 40m
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Spirit Airlines18h 15m012:35George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport06:50St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Spirit Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 21/04/2026 12:35:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 22/04/2026 06:50:00. 50 Economy ticket for £58 per person are available. Travel duration is 18h 15m
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United Airlines2h 8m020:20George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport22:28St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from United Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 21/04/2026 20:20:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 21/04/2026 22:28:00. 50 Economy ticket for £137 per person are available. Travel duration is 2h 8m
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Skyscanner2h 5m007:20George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport09:25St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Skyscanner goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 21/04/2026 07:20:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 21/04/2026 09:25:00. 50 Economy ticket for £137 per person are available. Travel duration is 2h 5m
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Alaska Airlines16h 59m007:00George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport23:59St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Alaska Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 21/04/2026 07:00:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 21/04/2026 23:59:00. 50 Economy ticket for £246 per person are available. Travel duration is 16h 59m
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Valley Transit30h 20m006:35HoustonSW Agencia Autobuses12:55St. Louis, MOGateway Station0EconomyA Bus from Valley Transit goes from SW Agencia Autobuses, Houston (USA) at 21/04/2026 06:35:00 to Gateway Station, St. Louis, MO (USA) arriving at 22/04/2026 12:55:00. 50 Economy ticket for £98 per person are available. Travel duration is 30h 20m
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FlixBus25h 30m011:25HoustonUptown/Upper Kirby12:55St. Louis, MOGateway Station0EconomyA Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 21/04/2026 11:25:00 to Gateway Station, St. Louis, MO (USA) arriving at 22/04/2026 12:55:00. 50 Economy ticket for £98 per person are available. Travel duration is 25h 30m
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FlixBus26h 55m019:50HoustonUptown/Upper Kirby22:45St. Louis, MOGateway Station0EconomyA Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 21/04/2026 19:50:00 to Gateway Station, St. Louis, MO (USA) arriving at 22/04/2026 22:45:00. 50 Economy ticket for £98 per person are available. Travel duration is 26h 55m
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Greyhound US23h 10m013:45HoustonHarrisburg Blvd Station12:55St. Louis, MOGateway Station0EconomyA Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 21/04/2026 13:45:00 to Gateway Station, St. Louis, MO (USA) arriving at 22/04/2026 12:55:00. 50 Economy ticket for £98 per person are available. Travel duration is 23h 10m
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Greyhound US27h 50m018:55HoustonHarrisburg Blvd Station22:45St. Louis, MOGateway Station0EconomyA Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 21/04/2026 18:55:00 to Gateway Station, St. Louis, MO (USA) arriving at 22/04/2026 22:45:00. 50 Economy ticket for £98 per person are available. Travel duration is 27h 50m
Cheapest Flights Tuesday
Cheapest Buses Tuesday
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Frontier Airlines28h 22m018:57George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport23:19St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Frontier Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 22/04/2026 18:57:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 23/04/2026 23:19:00. 50 Economy ticket for £72 per person are available. Travel duration is 28h 22m
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Spirit Airlines21h 55m012:35George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport10:30St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Spirit Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 22/04/2026 12:35:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 23/04/2026 10:30:00. 50 Economy ticket for £118 per person are available. Travel duration is 21h 55m
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United Airlines2h 8m020:20George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport22:28St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from United Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 22/04/2026 20:20:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 22/04/2026 22:28:00. 50 Economy ticket for £137 per person are available. Travel duration is 2h 8m
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Skyscanner2h 5m007:20George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport09:25St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Skyscanner goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 22/04/2026 07:20:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 22/04/2026 09:25:00. 50 Economy ticket for £137 per person are available. Travel duration is 2h 5m
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Alaska Airlines16h 59m007:00George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport23:59St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Alaska Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 22/04/2026 07:00:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 22/04/2026 23:59:00. 50 Economy ticket for £287 per person are available. Travel duration is 16h 59m
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FlixBus25h 30m011:25HoustonUptown/Upper Kirby12:55St. Louis, MOGateway Station0EconomyA Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 22/04/2026 11:25:00 to Gateway Station, St. Louis, MO (USA) arriving at 23/04/2026 12:55:00. 50 Economy ticket for £95 per person are available. Travel duration is 25h 30m
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Greyhound US23h 10m013:45HoustonHarrisburg Blvd Station12:55St. Louis, MOGateway Station0EconomyA Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 22/04/2026 13:45:00 to Gateway Station, St. Louis, MO (USA) arriving at 23/04/2026 12:55:00. 50 Economy ticket for £96 per person are available. Travel duration is 23h 10m
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Greyhound US27h 50m018:55HoustonHarrisburg Blvd Station22:45St. Louis, MOGateway Station0EconomyA Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 22/04/2026 18:55:00 to Gateway Station, St. Louis, MO (USA) arriving at 23/04/2026 22:45:00. 50 Economy ticket for £96 per person are available. Travel duration is 27h 50m
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FlixBus25h 45m011:10HoustonDowntown Houston12:55St. Louis, MOGateway Station0EconomyA Bus from FlixBus goes from Downtown Houston, Houston (USA) at 22/04/2026 11:10:00 to Gateway Station, St. Louis, MO (USA) arriving at 23/04/2026 12:55:00. 50 Economy ticket for £96 per person are available. Travel duration is 25h 45m
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Valley Transit30h 20m006:35HoustonSW Agencia Autobuses12:55St. Louis, MOGateway Station0EconomyA Bus from Valley Transit goes from SW Agencia Autobuses, Houston (USA) at 22/04/2026 06:35:00 to Gateway Station, St. Louis, MO (USA) arriving at 23/04/2026 12:55:00. 50 Economy ticket for £97 per person are available. Travel duration is 30h 20m
Cheapest Flights Wednesday
Cheapest Buses Wednesday
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Frontier Airlines8h 46m010:35George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport19:21St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Frontier Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 23/04/2026 10:35:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 23/04/2026 19:21:00. 50 Economy ticket for £67 per person are available. Travel duration is 8h 46m
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Frontier Airlines12h 36m006:45George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport19:21St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Frontier Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 23/04/2026 06:45:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 23/04/2026 19:21:00. 50 Economy ticket for £72 per person are available. Travel duration is 12h 36m
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United Airlines2h 8m020:20George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport22:28St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from United Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 23/04/2026 20:20:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 23/04/2026 22:28:00. 50 Economy ticket for £119 per person are available. Travel duration is 2h 8m
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United Airlines2h 5m007:20George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport09:25St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from United Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 23/04/2026 07:20:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 23/04/2026 09:25:00. 50 Economy ticket for £125 per person are available. Travel duration is 2h 5m
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Spirit Airlines18h 15m012:35George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport06:50St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Spirit Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 23/04/2026 12:35:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 24/04/2026 06:50:00. 50 Economy ticket for £133 per person are available. Travel duration is 18h 15m
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Greyhound US20h 55m001:50HoustonHarrisburg Blvd Station22:45St. Louis, MOGateway Station0EconomyA Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 23/04/2026 01:50:00 to Gateway Station, St. Louis, MO (USA) arriving at 23/04/2026 22:45:00. 50 Economy ticket for £82 per person are available. Travel duration is 20h 55m
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Greyhound US23h 10m013:45HoustonHarrisburg Blvd Station12:55St. Louis, MOGateway Station0EconomyA Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 23/04/2026 13:45:00 to Gateway Station, St. Louis, MO (USA) arriving at 24/04/2026 12:55:00. 50 Economy ticket for £82 per person are available. Travel duration is 23h 10m
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Greyhound Lines Mexico37h 15m009:30HoustonSW Agencia Autobuses22:45St. Louis, MOGateway Station0EconomyA Bus from Greyhound Lines Mexico goes from SW Agencia Autobuses, Houston (USA) at 23/04/2026 09:30:00 to Gateway Station, St. Louis, MO (USA) arriving at 24/04/2026 22:45:00. 50 Economy ticket for £82 per person are available. Travel duration is 37h 15m
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FlixBus22h 15m008:55HoustonUptown/Upper Kirby07:10St. Louis, MOGateway Station0EconomyA Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 23/04/2026 08:55:00 to Gateway Station, St. Louis, MO (USA) arriving at 24/04/2026 07:10:00. 50 Economy ticket for £82 per person are available. Travel duration is 22h 15m
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FlixBus20h 35m010:35HoustonDowntown Houston07:10St. Louis, MOGateway Station0EconomyA Bus from FlixBus goes from Downtown Houston, Houston (USA) at 23/04/2026 10:35:00 to Gateway Station, St. Louis, MO (USA) arriving at 24/04/2026 07:10:00. 50 Economy ticket for £82 per person are available. Travel duration is 20h 35m
Cheapest Flights Thursday
Cheapest Buses Thursday
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Frontier Airlines12h 36m018:14George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport06:50St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Frontier Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 24/04/2026 18:14:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 25/04/2026 06:50:00. 50 Economy ticket for £85 per person are available. Travel duration is 12h 36m
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Frontier Airlines24h 40m006:10George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport06:50St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Frontier Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 24/04/2026 06:10:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 25/04/2026 06:50:00. 50 Economy ticket for £99 per person are available. Travel duration is 24h 40m
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Spirit Airlines18h 15m012:35George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport06:50St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Spirit Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 24/04/2026 12:35:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 25/04/2026 06:50:00. 50 Economy ticket for £99 per person are available. Travel duration is 18h 15m
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Spirit Airlines9h 21m013:58George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport23:19St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Spirit Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 24/04/2026 13:58:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 24/04/2026 23:19:00. 50 Economy ticket for £145 per person are available. Travel duration is 9h 21m
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United Airlines2h 7m020:20George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport22:27St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from United Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 24/04/2026 20:20:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 24/04/2026 22:27:00. 50 Economy ticket for £157 per person are available. Travel duration is 2h 7m
Cheapest Flights Friday
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Frontier Airlines9h 18m014:01George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport23:19St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Frontier Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 25/04/2026 14:01:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 25/04/2026 23:19:00. 50 Economy ticket for £52 per person are available. Travel duration is 9h 18m
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Spirit Airlines16h 19m007:00George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport23:19St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Spirit Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 25/04/2026 07:00:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 25/04/2026 23:19:00. 50 Economy ticket for £111 per person are available. Travel duration is 16h 19m
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United Airlines2h 8m020:20George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport22:28St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from United Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 25/04/2026 20:20:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 25/04/2026 22:28:00. 50 Economy ticket for £118 per person are available. Travel duration is 2h 8m
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Skyscanner2h 5m007:20George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport09:25St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Skyscanner goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 25/04/2026 07:20:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 25/04/2026 09:25:00. 50 Economy ticket for £118 per person are available. Travel duration is 2h 5m
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Alaska Airlines16h 59m007:00George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport23:59St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Alaska Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 25/04/2026 07:00:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 25/04/2026 23:59:00. 50 Economy ticket for £356 per person are available. Travel duration is 16h 59m
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Greyhound US22h 55m008:15HoustonHarrisburg Blvd Station07:10St. Louis, MOGateway Station0EconomyA Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 25/04/2026 08:15:00 to Gateway Station, St. Louis, MO (USA) arriving at 26/04/2026 07:10:00. 50 Economy ticket for £92 per person are available. Travel duration is 22h 55m
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Greyhound US20h 55m001:50HoustonHarrisburg Blvd Station22:45St. Louis, MOGateway Station0EconomyA Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 25/04/2026 01:50:00 to Gateway Station, St. Louis, MO (USA) arriving at 25/04/2026 22:45:00. 50 Economy ticket for £93 per person are available. Travel duration is 20h 55m
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FlixBus20h 35m010:35HoustonDowntown Houston07:10St. Louis, MOGateway Station0EconomyA Bus from FlixBus goes from Downtown Houston, Houston (USA) at 25/04/2026 10:35:00 to Gateway Station, St. Louis, MO (USA) arriving at 26/04/2026 07:10:00. 50 Economy ticket for £93 per person are available. Travel duration is 20h 35m
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Valley Transit30h 20m006:35HoustonSW Agencia Autobuses12:55St. Louis, MOGateway Station0EconomyA Bus from Valley Transit goes from SW Agencia Autobuses, Houston (USA) at 25/04/2026 06:35:00 to Gateway Station, St. Louis, MO (USA) arriving at 26/04/2026 12:55:00. 50 Economy ticket for £94 per person are available. Travel duration is 30h 20m
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Greyhound Lines Mexico37h 15m009:30HoustonSW Agencia Autobuses22:45St. Louis, MOGateway Station0EconomyA Bus from Greyhound Lines Mexico goes from SW Agencia Autobuses, Houston (USA) at 25/04/2026 09:30:00 to Gateway Station, St. Louis, MO (USA) arriving at 26/04/2026 22:45:00. 50 Economy ticket for £94 per person are available. Travel duration is 37h 15m
Cheapest Flights Saturday
Cheapest Buses Saturday
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Greyhound US22h 55m008:15HoustonHarrisburg Blvd Station07:10St. Louis, MOGateway Station0EconomyA Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 26/04/2026 08:15:00 to Gateway Station, St. Louis, MO (USA) arriving at 27/04/2026 07:10:00. 50 Economy ticket for £85 per person are available. Travel duration is 22h 55m
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FlixBus26h 55m019:50HoustonUptown/Upper Kirby22:45St. Louis, MOGateway Station0EconomyA Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 26/04/2026 19:50:00 to Gateway Station, St. Louis, MO (USA) arriving at 27/04/2026 22:45:00. 50 Economy ticket for £85 per person are available. Travel duration is 26h 55m
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FlixBus20h 35m010:35HoustonDowntown Houston07:10St. Louis, MOGateway Station0EconomyA Bus from FlixBus goes from Downtown Houston, Houston (USA) at 26/04/2026 10:35:00 to Gateway Station, St. Louis, MO (USA) arriving at 27/04/2026 07:10:00. 50 Economy ticket for £85 per person are available. Travel duration is 20h 35m
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Greyhound US20h 55m001:50HoustonHarrisburg Blvd Station22:45St. Louis, MOGateway Station0EconomyA Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 26/04/2026 01:50:00 to Gateway Station, St. Louis, MO (USA) arriving at 26/04/2026 22:45:00. 50 Economy ticket for £86 per person are available. Travel duration is 20h 55m
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Greyhound Lines Mexico37h 15m009:30HoustonSW Agencia Autobuses22:45St. Louis, MOGateway Station0EconomyA Bus from Greyhound Lines Mexico goes from SW Agencia Autobuses, Houston (USA) at 26/04/2026 09:30:00 to Gateway Station, St. Louis, MO (USA) arriving at 27/04/2026 22:45:00. 50 Economy ticket for £86 per person are available. Travel duration is 37h 15m
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Frontier Airlines24h 50m006:00George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport06:50St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Frontier Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 26/04/2026 06:00:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 27/04/2026 06:50:00. 50 Economy ticket for £99 per person are available. Travel duration is 24h 50m
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Frontier Airlines12h 36m018:14George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport06:50St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Frontier Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 26/04/2026 18:14:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 27/04/2026 06:50:00. 50 Economy ticket for £99 per person are available. Travel duration is 12h 36m
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Spirit Airlines18h 15m012:35George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport06:50St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Spirit Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 26/04/2026 12:35:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 27/04/2026 06:50:00. 50 Economy ticket for £99 per person are available. Travel duration is 18h 15m
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United Airlines2h 5m007:20George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport09:25St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from United Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 26/04/2026 07:20:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 26/04/2026 09:25:00. 50 Economy ticket for £157 per person are available. Travel duration is 2h 5m
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United Airlines2h 8m020:20George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport22:28St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from United Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 26/04/2026 20:20:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 26/04/2026 22:28:00. 50 Economy ticket for £157 per person are available. Travel duration is 2h 8m
Cheapest Buses Sunday
Cheapest Flights Sunday
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Frontier Airlines27h 31m019:48George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport23:19St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Frontier Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 27/04/2026 19:48:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 28/04/2026 23:19:00. 50 Economy ticket for £57 per person are available. Travel duration is 27h 31m
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United Airlines2h 8m020:20George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport22:28St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from United Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 27/04/2026 20:20:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 27/04/2026 22:28:00. 50 Economy ticket for £109 per person are available. Travel duration is 2h 8m
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Spirit Airlines16h 19m007:00George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport23:19St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Spirit Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 27/04/2026 07:00:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 27/04/2026 23:19:00. 50 Economy ticket for £113 per person are available. Travel duration is 16h 19m
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Skyscanner2h 5m007:20George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport09:25St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Skyscanner goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 27/04/2026 07:20:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 27/04/2026 09:25:00. 50 Economy ticket for £232 per person are available. Travel duration is 2h 5m
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Alaska Airlines31h 13m016:46George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport23:59St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Alaska Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 27/04/2026 16:46:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 28/04/2026 23:59:00. 50 Economy ticket for £359 per person are available. Travel duration is 31h 13m
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FlixBus22h 15m008:55HoustonUptown/Upper Kirby07:10St. Louis, MOGateway Station0EconomyA Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 27/04/2026 08:55:00 to Gateway Station, St. Louis, MO (USA) arriving at 28/04/2026 07:10:00. 50 Economy ticket for £84 per person are available. Travel duration is 22h 15m
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Greyhound US20h 55m001:50HoustonHarrisburg Blvd Station22:45St. Louis, MOGateway Station0EconomyA Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 27/04/2026 01:50:00 to Gateway Station, St. Louis, MO (USA) arriving at 27/04/2026 22:45:00. 50 Economy ticket for £85 per person are available. Travel duration is 20h 55m
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Greyhound US22h 55m008:15HoustonHarrisburg Blvd Station07:10St. Louis, MOGateway Station0EconomyA Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 27/04/2026 08:15:00 to Gateway Station, St. Louis, MO (USA) arriving at 28/04/2026 07:10:00. 50 Economy ticket for £85 per person are available. Travel duration is 22h 55m
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FlixBus25h 30m011:25HoustonUptown/Upper Kirby12:55St. Louis, MOGateway Station0EconomyA Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 27/04/2026 11:25:00 to Gateway Station, St. Louis, MO (USA) arriving at 28/04/2026 12:55:00. 50 Economy ticket for £85 per person are available. Travel duration is 25h 30m
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Valley Transit30h 20m006:35HoustonSW Agencia Autobuses12:55St. Louis, MOGateway Station0EconomyA Bus from Valley Transit goes from SW Agencia Autobuses, Houston (USA) at 27/04/2026 06:35:00 to Gateway Station, St. Louis, MO (USA) arriving at 28/04/2026 12:55:00. 50 Economy ticket for £87 per person are available. Travel duration is 30h 20m
Cheapest Flights Monday
Cheapest Buses Monday
What are the fastest trips from Houston to St. Louis, MO?
You can get to St. Louis, MO from Houston in just 2h 5m with a Flight from Skyscanner. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
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Skyscanner2h 5m007:20George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport09:25St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Skyscanner goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 21/04/2026 07:20:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 21/04/2026 09:25:00. 50 Economy ticket for £137 per person are available. Travel duration is 2h 5m
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United Airlines2h 8m020:20George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport22:28St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from United Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 21/04/2026 20:20:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 21/04/2026 22:28:00. 50 Economy ticket for £137 per person are available. Travel duration is 2h 8m
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Alaska Airlines16h 59m007:00George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport23:59St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Alaska Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 21/04/2026 07:00:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 21/04/2026 23:59:00. 50 Economy ticket for £246 per person are available. Travel duration is 16h 59m
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Spirit Airlines18h 15m012:35George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport06:50St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Spirit Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 21/04/2026 12:35:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 22/04/2026 06:50:00. 50 Economy ticket for £58 per person are available. Travel duration is 18h 15m
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Frontier Airlines24h 40m006:10George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport06:50St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Frontier Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 21/04/2026 06:10:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 22/04/2026 06:50:00. 50 Economy ticket for £51 per person are available. Travel duration is 24h 40m
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Greyhound US23h 10m013:45HoustonHarrisburg Blvd Station12:55St. Louis, MOGateway Station0EconomyA Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 21/04/2026 13:45:00 to Gateway Station, St. Louis, MO (USA) arriving at 22/04/2026 12:55:00. 50 Economy ticket for £98 per person are available. Travel duration is 23h 10m
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FlixBus25h 30m011:25HoustonUptown/Upper Kirby12:55St. Louis, MOGateway Station0EconomyA Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 21/04/2026 11:25:00 to Gateway Station, St. Louis, MO (USA) arriving at 22/04/2026 12:55:00. 50 Economy ticket for £98 per person are available. Travel duration is 25h 30m
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FlixBus26h 55m019:50HoustonUptown/Upper Kirby22:45St. Louis, MOGateway Station0EconomyA Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 21/04/2026 19:50:00 to Gateway Station, St. Louis, MO (USA) arriving at 22/04/2026 22:45:00. 50 Economy ticket for £98 per person are available. Travel duration is 26h 55m
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Greyhound US27h 50m018:55HoustonHarrisburg Blvd Station22:45St. Louis, MOGateway Station0EconomyA Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 21/04/2026 18:55:00 to Gateway Station, St. Louis, MO (USA) arriving at 22/04/2026 22:45:00. 50 Economy ticket for £98 per person are available. Travel duration is 27h 50m
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Valley Transit30h 20m006:35HoustonSW Agencia Autobuses12:55St. Louis, MOGateway Station0EconomyA Bus from Valley Transit goes from SW Agencia Autobuses, Houston (USA) at 21/04/2026 06:35:00 to Gateway Station, St. Louis, MO (USA) arriving at 22/04/2026 12:55:00. 50 Economy ticket for £98 per person are available. Travel duration is 30h 20m
Fastest Flights Tuesday
Fastest Buses Tuesday
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Skyscanner2h 5m007:20George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport09:25St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Skyscanner goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 22/04/2026 07:20:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 22/04/2026 09:25:00. 50 Economy ticket for £137 per person are available. Travel duration is 2h 5m
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United Airlines2h 8m020:20George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport22:28St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from United Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 22/04/2026 20:20:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 22/04/2026 22:28:00. 50 Economy ticket for £137 per person are available. Travel duration is 2h 8m
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Alaska Airlines16h 59m007:00George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport23:59St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Alaska Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 22/04/2026 07:00:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 22/04/2026 23:59:00. 50 Economy ticket for £287 per person are available. Travel duration is 16h 59m
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Spirit Airlines21h 55m012:35George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport10:30St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Spirit Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 22/04/2026 12:35:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 23/04/2026 10:30:00. 50 Economy ticket for £118 per person are available. Travel duration is 21h 55m
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Frontier Airlines28h 22m018:57George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport23:19St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Frontier Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 22/04/2026 18:57:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 23/04/2026 23:19:00. 50 Economy ticket for £72 per person are available. Travel duration is 28h 22m
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Greyhound US23h 10m013:45HoustonHarrisburg Blvd Station12:55St. Louis, MOGateway Station0EconomyA Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 22/04/2026 13:45:00 to Gateway Station, St. Louis, MO (USA) arriving at 23/04/2026 12:55:00. 50 Economy ticket for £96 per person are available. Travel duration is 23h 10m
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FlixBus25h 30m011:25HoustonUptown/Upper Kirby12:55St. Louis, MOGateway Station0EconomyA Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 22/04/2026 11:25:00 to Gateway Station, St. Louis, MO (USA) arriving at 23/04/2026 12:55:00. 50 Economy ticket for £95 per person are available. Travel duration is 25h 30m
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FlixBus25h 45m011:10HoustonDowntown Houston12:55St. Louis, MOGateway Station0EconomyA Bus from FlixBus goes from Downtown Houston, Houston (USA) at 22/04/2026 11:10:00 to Gateway Station, St. Louis, MO (USA) arriving at 23/04/2026 12:55:00. 50 Economy ticket for £96 per person are available. Travel duration is 25h 45m
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Greyhound US27h 50m018:55HoustonHarrisburg Blvd Station22:45St. Louis, MOGateway Station0EconomyA Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 22/04/2026 18:55:00 to Gateway Station, St. Louis, MO (USA) arriving at 23/04/2026 22:45:00. 50 Economy ticket for £96 per person are available. Travel duration is 27h 50m
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Valley Transit30h 20m006:35HoustonSW Agencia Autobuses12:55St. Louis, MOGateway Station0EconomyA Bus from Valley Transit goes from SW Agencia Autobuses, Houston (USA) at 22/04/2026 06:35:00 to Gateway Station, St. Louis, MO (USA) arriving at 23/04/2026 12:55:00. 50 Economy ticket for £97 per person are available. Travel duration is 30h 20m
Fastest Flights Wednesday
Fastest Buses Wednesday
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United Airlines2h 5m007:20George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport09:25St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from United Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 23/04/2026 07:20:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 23/04/2026 09:25:00. 50 Economy ticket for £125 per person are available. Travel duration is 2h 5m
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United Airlines2h 8m020:20George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport22:28St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from United Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 23/04/2026 20:20:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 23/04/2026 22:28:00. 50 Economy ticket for £119 per person are available. Travel duration is 2h 8m
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Frontier Airlines8h 46m010:35George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport19:21St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Frontier Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 23/04/2026 10:35:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 23/04/2026 19:21:00. 50 Economy ticket for £67 per person are available. Travel duration is 8h 46m
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Frontier Airlines12h 36m006:45George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport19:21St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Frontier Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 23/04/2026 06:45:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 23/04/2026 19:21:00. 50 Economy ticket for £72 per person are available. Travel duration is 12h 36m
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Spirit Airlines18h 15m012:35George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport06:50St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Spirit Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 23/04/2026 12:35:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 24/04/2026 06:50:00. 50 Economy ticket for £133 per person are available. Travel duration is 18h 15m
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FlixBus20h 35m010:35HoustonDowntown Houston07:10St. Louis, MOGateway Station0EconomyA Bus from FlixBus goes from Downtown Houston, Houston (USA) at 23/04/2026 10:35:00 to Gateway Station, St. Louis, MO (USA) arriving at 24/04/2026 07:10:00. 50 Economy ticket for £82 per person are available. Travel duration is 20h 35m
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Greyhound US20h 55m001:50HoustonHarrisburg Blvd Station22:45St. Louis, MOGateway Station0EconomyA Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 23/04/2026 01:50:00 to Gateway Station, St. Louis, MO (USA) arriving at 23/04/2026 22:45:00. 50 Economy ticket for £82 per person are available. Travel duration is 20h 55m
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FlixBus22h 15m008:55HoustonUptown/Upper Kirby07:10St. Louis, MOGateway Station0EconomyA Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 23/04/2026 08:55:00 to Gateway Station, St. Louis, MO (USA) arriving at 24/04/2026 07:10:00. 50 Economy ticket for £82 per person are available. Travel duration is 22h 15m
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Greyhound US23h 10m013:45HoustonHarrisburg Blvd Station12:55St. Louis, MOGateway Station0EconomyA Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 23/04/2026 13:45:00 to Gateway Station, St. Louis, MO (USA) arriving at 24/04/2026 12:55:00. 50 Economy ticket for £82 per person are available. Travel duration is 23h 10m
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Greyhound Lines Mexico37h 15m009:30HoustonSW Agencia Autobuses22:45St. Louis, MOGateway Station0EconomyA Bus from Greyhound Lines Mexico goes from SW Agencia Autobuses, Houston (USA) at 23/04/2026 09:30:00 to Gateway Station, St. Louis, MO (USA) arriving at 24/04/2026 22:45:00. 50 Economy ticket for £82 per person are available. Travel duration is 37h 15m
Fastest Flights Thursday
Fastest Buses Thursday
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United Airlines2h 7m020:20George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport22:27St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from United Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 24/04/2026 20:20:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 24/04/2026 22:27:00. 50 Economy ticket for £157 per person are available. Travel duration is 2h 7m
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Spirit Airlines9h 21m013:58George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport23:19St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Spirit Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 24/04/2026 13:58:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 24/04/2026 23:19:00. 50 Economy ticket for £145 per person are available. Travel duration is 9h 21m
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Frontier Airlines12h 36m018:14George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport06:50St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Frontier Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 24/04/2026 18:14:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 25/04/2026 06:50:00. 50 Economy ticket for £85 per person are available. Travel duration is 12h 36m
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Spirit Airlines18h 15m012:35George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport06:50St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Spirit Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 24/04/2026 12:35:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 25/04/2026 06:50:00. 50 Economy ticket for £99 per person are available. Travel duration is 18h 15m
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Frontier Airlines24h 40m006:10George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport06:50St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Frontier Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 24/04/2026 06:10:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 25/04/2026 06:50:00. 50 Economy ticket for £99 per person are available. Travel duration is 24h 40m
Fastest Flights Friday
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Skyscanner2h 5m007:20George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport09:25St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Skyscanner goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 25/04/2026 07:20:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 25/04/2026 09:25:00. 50 Economy ticket for £118 per person are available. Travel duration is 2h 5m
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United Airlines2h 8m020:20George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport22:28St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from United Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 25/04/2026 20:20:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 25/04/2026 22:28:00. 50 Economy ticket for £118 per person are available. Travel duration is 2h 8m
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Frontier Airlines9h 18m014:01George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport23:19St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Frontier Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 25/04/2026 14:01:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 25/04/2026 23:19:00. 50 Economy ticket for £52 per person are available. Travel duration is 9h 18m
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Spirit Airlines16h 19m007:00George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport23:19St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Spirit Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 25/04/2026 07:00:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 25/04/2026 23:19:00. 50 Economy ticket for £111 per person are available. Travel duration is 16h 19m
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Alaska Airlines16h 59m007:00George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport23:59St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Alaska Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 25/04/2026 07:00:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 25/04/2026 23:59:00. 50 Economy ticket for £356 per person are available. Travel duration is 16h 59m
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FlixBus20h 35m010:35HoustonDowntown Houston07:10St. Louis, MOGateway Station0EconomyA Bus from FlixBus goes from Downtown Houston, Houston (USA) at 25/04/2026 10:35:00 to Gateway Station, St. Louis, MO (USA) arriving at 26/04/2026 07:10:00. 50 Economy ticket for £93 per person are available. Travel duration is 20h 35m
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Greyhound US20h 55m001:50HoustonHarrisburg Blvd Station22:45St. Louis, MOGateway Station0EconomyA Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 25/04/2026 01:50:00 to Gateway Station, St. Louis, MO (USA) arriving at 25/04/2026 22:45:00. 50 Economy ticket for £93 per person are available. Travel duration is 20h 55m
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Greyhound US22h 55m008:15HoustonHarrisburg Blvd Station07:10St. Louis, MOGateway Station0EconomyA Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 25/04/2026 08:15:00 to Gateway Station, St. Louis, MO (USA) arriving at 26/04/2026 07:10:00. 50 Economy ticket for £92 per person are available. Travel duration is 22h 55m
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Valley Transit30h 20m006:35HoustonSW Agencia Autobuses12:55St. Louis, MOGateway Station0EconomyA Bus from Valley Transit goes from SW Agencia Autobuses, Houston (USA) at 25/04/2026 06:35:00 to Gateway Station, St. Louis, MO (USA) arriving at 26/04/2026 12:55:00. 50 Economy ticket for £94 per person are available. Travel duration is 30h 20m
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Greyhound Lines Mexico37h 15m009:30HoustonSW Agencia Autobuses22:45St. Louis, MOGateway Station0EconomyA Bus from Greyhound Lines Mexico goes from SW Agencia Autobuses, Houston (USA) at 25/04/2026 09:30:00 to Gateway Station, St. Louis, MO (USA) arriving at 26/04/2026 22:45:00. 50 Economy ticket for £94 per person are available. Travel duration is 37h 15m
Fastest Flights Saturday
Fastest Buses Saturday
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United Airlines2h 5m007:20George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport09:25St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from United Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 26/04/2026 07:20:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 26/04/2026 09:25:00. 50 Economy ticket for £157 per person are available. Travel duration is 2h 5m
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United Airlines2h 8m020:20George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport22:28St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from United Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 26/04/2026 20:20:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 26/04/2026 22:28:00. 50 Economy ticket for £157 per person are available. Travel duration is 2h 8m
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Frontier Airlines12h 36m018:14George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport06:50St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Frontier Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 26/04/2026 18:14:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 27/04/2026 06:50:00. 50 Economy ticket for £99 per person are available. Travel duration is 12h 36m
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Spirit Airlines18h 15m012:35George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport06:50St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Spirit Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 26/04/2026 12:35:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 27/04/2026 06:50:00. 50 Economy ticket for £99 per person are available. Travel duration is 18h 15m
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Frontier Airlines24h 50m006:00George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport06:50St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Frontier Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 26/04/2026 06:00:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 27/04/2026 06:50:00. 50 Economy ticket for £99 per person are available. Travel duration is 24h 50m
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FlixBus20h 35m010:35HoustonDowntown Houston07:10St. Louis, MOGateway Station0EconomyA Bus from FlixBus goes from Downtown Houston, Houston (USA) at 26/04/2026 10:35:00 to Gateway Station, St. Louis, MO (USA) arriving at 27/04/2026 07:10:00. 50 Economy ticket for £85 per person are available. Travel duration is 20h 35m
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Greyhound US20h 55m001:50HoustonHarrisburg Blvd Station22:45St. Louis, MOGateway Station0EconomyA Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 26/04/2026 01:50:00 to Gateway Station, St. Louis, MO (USA) arriving at 26/04/2026 22:45:00. 50 Economy ticket for £86 per person are available. Travel duration is 20h 55m
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Greyhound US22h 55m008:15HoustonHarrisburg Blvd Station07:10St. Louis, MOGateway Station0EconomyA Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 26/04/2026 08:15:00 to Gateway Station, St. Louis, MO (USA) arriving at 27/04/2026 07:10:00. 50 Economy ticket for £85 per person are available. Travel duration is 22h 55m
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FlixBus26h 55m019:50HoustonUptown/Upper Kirby22:45St. Louis, MOGateway Station0EconomyA Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 26/04/2026 19:50:00 to Gateway Station, St. Louis, MO (USA) arriving at 27/04/2026 22:45:00. 50 Economy ticket for £85 per person are available. Travel duration is 26h 55m
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Greyhound Lines Mexico37h 15m009:30HoustonSW Agencia Autobuses22:45St. Louis, MOGateway Station0EconomyA Bus from Greyhound Lines Mexico goes from SW Agencia Autobuses, Houston (USA) at 26/04/2026 09:30:00 to Gateway Station, St. Louis, MO (USA) arriving at 27/04/2026 22:45:00. 50 Economy ticket for £86 per person are available. Travel duration is 37h 15m
Fastest Flights Sunday
Fastest Buses Sunday
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Skyscanner2h 5m007:20George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport09:25St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Skyscanner goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 27/04/2026 07:20:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 27/04/2026 09:25:00. 50 Economy ticket for £232 per person are available. Travel duration is 2h 5m
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United Airlines2h 8m020:20George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport22:28St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from United Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 27/04/2026 20:20:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 27/04/2026 22:28:00. 50 Economy ticket for £109 per person are available. Travel duration is 2h 8m
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Spirit Airlines16h 19m007:00George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport23:19St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Spirit Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 27/04/2026 07:00:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 27/04/2026 23:19:00. 50 Economy ticket for £113 per person are available. Travel duration is 16h 19m
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Frontier Airlines27h 31m019:48George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport23:19St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Frontier Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 27/04/2026 19:48:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 28/04/2026 23:19:00. 50 Economy ticket for £57 per person are available. Travel duration is 27h 31m
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Alaska Airlines31h 13m016:46George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport23:59St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Alaska Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 27/04/2026 16:46:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 28/04/2026 23:59:00. 50 Economy ticket for £359 per person are available. Travel duration is 31h 13m
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Greyhound US20h 55m001:50HoustonHarrisburg Blvd Station22:45St. Louis, MOGateway Station0EconomyA Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 27/04/2026 01:50:00 to Gateway Station, St. Louis, MO (USA) arriving at 27/04/2026 22:45:00. 50 Economy ticket for £85 per person are available. Travel duration is 20h 55m
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FlixBus22h 15m008:55HoustonUptown/Upper Kirby07:10St. Louis, MOGateway Station0EconomyA Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 27/04/2026 08:55:00 to Gateway Station, St. Louis, MO (USA) arriving at 28/04/2026 07:10:00. 50 Economy ticket for £84 per person are available. Travel duration is 22h 15m
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Greyhound US22h 55m008:15HoustonHarrisburg Blvd Station07:10St. Louis, MOGateway Station0EconomyA Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 27/04/2026 08:15:00 to Gateway Station, St. Louis, MO (USA) arriving at 28/04/2026 07:10:00. 50 Economy ticket for £85 per person are available. Travel duration is 22h 55m
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FlixBus25h 30m011:25HoustonUptown/Upper Kirby12:55St. Louis, MOGateway Station0EconomyA Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 27/04/2026 11:25:00 to Gateway Station, St. Louis, MO (USA) arriving at 28/04/2026 12:55:00. 50 Economy ticket for £85 per person are available. Travel duration is 25h 30m
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Valley Transit30h 20m006:35HoustonSW Agencia Autobuses12:55St. Louis, MOGateway Station0EconomyA Bus from Valley Transit goes from SW Agencia Autobuses, Houston (USA) at 27/04/2026 06:35:00 to Gateway Station, St. Louis, MO (USA) arriving at 28/04/2026 12:55:00. 50 Economy ticket for £87 per person are available. Travel duration is 30h 20m
Fastest Flights Monday
Fastest Buses Monday
Here you will find all operators and timetables for a
Bus from Houston to St. Louis, MO
What are the most popular stations in Houston and St. Louis, MO?
In Houston, you will usually depart from Hillcroft METRO Park and Ride Coach Station, Lockwood or Main St & Airline Dr, while in St. Louis, MO you will be arriving at Skinker Boulevard, Lindbergh @ Hackberry NB Bus Stop or Gateway Station, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to St. Louis, MO from Houston? With 9 connections between 5 Flight and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Houston and St. Louis, MO, you can pay as low as £51 with a Flight from Frontier Airlines.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Skyscanner: you will get to St. Louis, MO in just 2h 5m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Houston and St. Louis, MO are Greyhound US, FlixBus and Frontier Airlines, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Houston and St. Louis, MO is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from West University Place, TX or to Sauget, IL, and look at flights from William P. Hobby Airport, and landing at St. Louis Lambert Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Houston to St. Louis, MO?
The most popular companies between Houston and St. Louis, MO, are Greyhound US, FlixBus and Frontier Airlines. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: Greyhound US, FlixBus, Valley Transit and 1 more.
Airlines: Frontier Airlines, United Airlines, Spirit Airlines and 2 more.
All you need to know when you travel from Houston to St. Louis, MO
Check all information on comfort and services on all modes of transports from Houston to St. Louis, MO. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Houston to St. Louis, MO
How can I reach St. Louis, MO from Houston?
Every day, there are on average 9 connections between Flight and Bus, with which you can get to St. Louis, MO from Houston.
How far is St. Louis, MO from Houston?
The distance between Houston and St. Louis, MO is 1,094.8 km.
What is the most ecofriendly mode of transport between Houston and St. Louis, MO?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 30 kgs of CO2, a train 38 kgs, a car 186 kgs, and a flight 269 kgs.
What is the cheapest mode of transport from Houston to St. Louis, MO?
You can get to St. Louis, MO with just £51 by taking a Flight from Frontier Airlines.
What is the fastest way to get from Houston to St. Louis, MO?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to St. Louis, MO in just 2h 5m with a Flight from Skyscanner.
More routes to Houston and to St. Louis, MO
Looking for more options? Here you can see the most popular routes to Houston and to St. Louis, MO. Simply click on a connection, and you’ll find all the details about the route!
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