What is the best way to travel from Houston to St. Louis, MO?
Looking for a trip? Check and compare all the available Buses and Flights to St. Louis, MO from Houston. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 5 available companies to find your perfect trip!
What is the cheapest way to reach St. Louis, MO from Houston?
You can reach St. Louis, MO with just £111 by taking a Bus from Greyhound US, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
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FlixBus22h 40m017:05HoustonDowntown Houston15:45St. Louis, MOGateway Station0EconomyA Bus from FlixBus goes from Downtown Houston, Houston (USA) at 26/12/2025 17:05:00 to Gateway Station, St. Louis, MO (USA) arriving at 27/12/2025 15:45:00. 50 Economy ticket for £129 per person are available. Travel duration is 22h 40m
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Greyhound US25h 0m022:00HoustonHarrisburg Blvd Station23:00St. Louis, MOGateway Station0EconomyA Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 26/12/2025 22:00:00 to Gateway Station, St. Louis, MO (USA) arriving at 27/12/2025 23:00:00. 50 Economy ticket for £130 per person are available. Travel duration is 25h 0m
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FlixBus25h 55m013:50HoustonUptown/Upper Kirby15:45St. Louis, MOGateway Station0EconomyA Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 26/12/2025 13:50:00 to Gateway Station, St. Louis, MO (USA) arriving at 27/12/2025 15:45:00. 50 Economy ticket for £130 per person are available. Travel duration is 25h 55m
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Valley Transit30h 20m006:35HoustonSW Agencia Autobuses12:55St. Louis, MOGateway Station0EconomyA Bus from Valley Transit goes from SW Agencia Autobuses, Houston (USA) at 26/12/2025 06:35:00 to Gateway Station, St. Louis, MO (USA) arriving at 27/12/2025 12:55:00. 50 Economy ticket for £176 per person are available. Travel duration is 30h 20m
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Frontier Airlines12h 7m021:55George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport10:02St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Frontier Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 26/12/2025 21:55:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 27/12/2025 10:02:00. 50 Economy ticket for £175 per person are available. Travel duration is 12h 7m
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United Airlines2h 5m019:50George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport21:55St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from United Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 26/12/2025 19:50:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 26/12/2025 21:55:00. 50 Economy ticket for £329 per person are available. Travel duration is 2h 5m
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Skyscanner2h 4m007:45George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport09:49St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Skyscanner goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 26/12/2025 07:45:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 26/12/2025 09:49:00. 50 Economy ticket for £329 per person are available. Travel duration is 2h 4m
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Skyscanner2h 8m014:28George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport16:36St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Skyscanner goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 26/12/2025 14:28:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 26/12/2025 16:36:00. 50 Economy ticket for £329 per person are available. Travel duration is 2h 8m
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United Airlines5h 57m006:30George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport12:27St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from United Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 26/12/2025 06:30:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 26/12/2025 12:27:00. 50 Economy ticket for £336 per person are available. Travel duration is 5h 57m
Cheapest Buses Friday
Cheapest Flights Friday
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Greyhound US23h 10m013:45HoustonHarrisburg Blvd Station12:55St. Louis, MOGateway Station0EconomyA Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 27/12/2025 13:45:00 to Gateway Station, St. Louis, MO (USA) arriving at 28/12/2025 12:55:00. 50 Economy ticket for £111 per person are available. Travel duration is 23h 10m
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FlixBus28h 50m018:00HoustonDowntown Houston22:50St. Louis, MOGateway Station0EconomyA Bus from FlixBus goes from Downtown Houston, Houston (USA) at 27/12/2025 18:00:00 to Gateway Station, St. Louis, MO (USA) arriving at 28/12/2025 22:50:00. 50 Economy ticket for £111 per person are available. Travel duration is 28h 50m
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Greyhound Lines Mexico37h 20m009:30HoustonSW Agencia Autobuses22:50St. Louis, MOGateway Station0EconomyA Bus from Greyhound Lines Mexico goes from SW Agencia Autobuses, Houston (USA) at 27/12/2025 09:30:00 to Gateway Station, St. Louis, MO (USA) arriving at 28/12/2025 22:50:00. 50 Economy ticket for £112 per person are available. Travel duration is 37h 20m
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FlixBus25h 30m011:25HoustonUptown/Upper Kirby12:55St. Louis, MOGateway Station0EconomyA Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 27/12/2025 11:25:00 to Gateway Station, St. Louis, MO (USA) arriving at 28/12/2025 12:55:00. 50 Economy ticket for £112 per person are available. Travel duration is 25h 30m
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Greyhound US27h 50m019:00HoustonHarrisburg Blvd Station22:50St. Louis, MOGateway Station0EconomyA Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 27/12/2025 19:00:00 to Gateway Station, St. Louis, MO (USA) arriving at 28/12/2025 22:50:00. 50 Economy ticket for £113 per person are available. Travel duration is 27h 50m
Cheapest Buses Saturday
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FlixBus22h 40m017:05HoustonDowntown Houston15:45St. Louis, MOGateway Station0EconomyA Bus from FlixBus goes from Downtown Houston, Houston (USA) at 28/12/2025 17:05:00 to Gateway Station, St. Louis, MO (USA) arriving at 29/12/2025 15:45:00. 50 Economy ticket for £127 per person are available. Travel duration is 22h 40m
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Greyhound US27h 55m018:55HoustonHarrisburg Blvd Station22:50St. Louis, MOGateway Station0EconomyA Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 28/12/2025 18:55:00 to Gateway Station, St. Louis, MO (USA) arriving at 29/12/2025 22:50:00. 50 Economy ticket for £131 per person are available. Travel duration is 27h 55m
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FlixBus30h 20m006:35HoustonSW Agencia Autobuses12:55St. Louis, MOGateway Station0EconomyA Bus from FlixBus goes from SW Agencia Autobuses, Houston (USA) at 28/12/2025 06:35:00 to Gateway Station, St. Louis, MO (USA) arriving at 29/12/2025 12:55:00. 50 Economy ticket for £131 per person are available. Travel duration is 30h 20m
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Greyhound US23h 10m013:45HoustonHarrisburg Blvd Station12:55St. Louis, MOGateway Station0EconomyA Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 28/12/2025 13:45:00 to Gateway Station, St. Louis, MO (USA) arriving at 29/12/2025 12:55:00. 50 Economy ticket for £134 per person are available. Travel duration is 23h 10m
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Valley Transit30h 20m006:35HoustonSW Agencia Autobuses12:55St. Louis, MOGateway Station0EconomyA Bus from Valley Transit goes from SW Agencia Autobuses, Houston (USA) at 28/12/2025 06:35:00 to Gateway Station, St. Louis, MO (USA) arriving at 29/12/2025 12:55:00. 50 Economy ticket for £135 per person are available. Travel duration is 30h 20m
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Frontier Airlines12h 11m021:34George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport09:45St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Frontier Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 28/12/2025 21:34:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 29/12/2025 09:45:00. 50 Economy ticket for £153 per person are available. Travel duration is 12h 11m
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Frontier Airlines30h 53m014:32George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport21:25St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Frontier Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 28/12/2025 14:32:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 29/12/2025 21:25:00. 50 Economy ticket for £241 per person are available. Travel duration is 30h 53m
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United Airlines2h 5m019:50George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport21:55St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from United Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 28/12/2025 19:50:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 28/12/2025 21:55:00. 50 Economy ticket for £254 per person are available. Travel duration is 2h 5m
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Skyscanner2h 4m007:45George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport09:49St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Skyscanner goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 28/12/2025 07:45:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 28/12/2025 09:49:00. 50 Economy ticket for £255 per person are available. Travel duration is 2h 4m
Cheapest Buses Sunday
Cheapest Flights Sunday
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Greyhound US23h 10m013:45HoustonHarrisburg Blvd Station12:55St. Louis, MOGateway Station0EconomyA Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 29/12/2025 13:45:00 to Gateway Station, St. Louis, MO (USA) arriving at 30/12/2025 12:55:00. 50 Economy ticket for £119 per person are available. Travel duration is 23h 10m
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FlixBus22h 40m017:05HoustonDowntown Houston15:45St. Louis, MOGateway Station0EconomyA Bus from FlixBus goes from Downtown Houston, Houston (USA) at 29/12/2025 17:05:00 to Gateway Station, St. Louis, MO (USA) arriving at 30/12/2025 15:45:00. 50 Economy ticket for £119 per person are available. Travel duration is 22h 40m
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Greyhound US21h 0m001:50HoustonHarrisburg Blvd Station22:50St. Louis, MOGateway Station0EconomyA Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 29/12/2025 01:50:00 to Gateway Station, St. Louis, MO (USA) arriving at 29/12/2025 22:50:00. 50 Economy ticket for £120 per person are available. Travel duration is 21h 0m
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Valley Transit30h 20m006:35HoustonSW Agencia Autobuses12:55St. Louis, MOGateway Station0EconomyA Bus from Valley Transit goes from SW Agencia Autobuses, Houston (USA) at 29/12/2025 06:35:00 to Gateway Station, St. Louis, MO (USA) arriving at 30/12/2025 12:55:00. 50 Economy ticket for £120 per person are available. Travel duration is 30h 20m
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FlixBus22h 15m008:55HoustonUptown/Upper Kirby07:10St. Louis, MOGateway Station0EconomyA Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 29/12/2025 08:55:00 to Gateway Station, St. Louis, MO (USA) arriving at 30/12/2025 07:10:00. 50 Economy ticket for £120 per person are available. Travel duration is 22h 15m
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Frontier Airlines15h 35m018:05George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport09:40St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Frontier Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 29/12/2025 18:05:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 30/12/2025 09:40:00. 50 Economy ticket for £219 per person are available. Travel duration is 15h 35m
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Frontier Airlines27h 40m006:00George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport09:40St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Frontier Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 29/12/2025 06:00:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 30/12/2025 09:40:00. 50 Economy ticket for £223 per person are available. Travel duration is 27h 40m
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Spirit Airlines18h 31m015:09George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport09:40St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Spirit Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 29/12/2025 15:09:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 30/12/2025 09:40:00. 50 Economy ticket for £238 per person are available. Travel duration is 18h 31m
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Spirit Airlines16h 47m005:46George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport22:33St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Spirit Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 29/12/2025 05:46:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 29/12/2025 22:33:00. 50 Economy ticket for £247 per person are available. Travel duration is 16h 47m
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United Airlines7h 27m005:00George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport12:27St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from United Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 29/12/2025 05:00:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 29/12/2025 12:27:00. 50 Economy ticket for £261 per person are available. Travel duration is 7h 27m
Cheapest Buses Monday
Cheapest Flights Monday
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Greyhound US23h 10m013:45HoustonHarrisburg Blvd Station12:55St. Louis, MOGateway Station0EconomyA Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 30/12/2025 13:45:00 to Gateway Station, St. Louis, MO (USA) arriving at 31/12/2025 12:55:00. 50 Economy ticket for £127 per person are available. Travel duration is 23h 10m
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Greyhound US27h 55m018:55HoustonHarrisburg Blvd Station22:50St. Louis, MOGateway Station0EconomyA Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 30/12/2025 18:55:00 to Gateway Station, St. Louis, MO (USA) arriving at 31/12/2025 22:50:00. 50 Economy ticket for £127 per person are available. Travel duration is 27h 55m
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FlixBus27h 15m019:35HoustonDowntown Houston22:50St. Louis, MOGateway Station0EconomyA Bus from FlixBus goes from Downtown Houston, Houston (USA) at 30/12/2025 19:35:00 to Gateway Station, St. Louis, MO (USA) arriving at 31/12/2025 22:50:00. 50 Economy ticket for £127 per person are available. Travel duration is 27h 15m
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FlixBus27h 0m019:50HoustonUptown/Upper Kirby22:50St. Louis, MOGateway Station0EconomyA Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 30/12/2025 19:50:00 to Gateway Station, St. Louis, MO (USA) arriving at 31/12/2025 22:50:00. 50 Economy ticket for £127 per person are available. Travel duration is 27h 0m
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Valley Transit30h 20m006:35HoustonSW Agencia Autobuses12:55St. Louis, MOGateway Station0EconomyA Bus from Valley Transit goes from SW Agencia Autobuses, Houston (USA) at 30/12/2025 06:35:00 to Gateway Station, St. Louis, MO (USA) arriving at 31/12/2025 12:55:00. 50 Economy ticket for £128 per person are available. Travel duration is 30h 20m
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United Airlines2h 5m019:50George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport21:55St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from United Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 30/12/2025 19:50:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 30/12/2025 21:55:00. 50 Economy ticket for £255 per person are available. Travel duration is 2h 5m
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Skyscanner2h 4m007:45George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport09:49St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Skyscanner goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 30/12/2025 07:45:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 30/12/2025 09:49:00. 50 Economy ticket for £255 per person are available. Travel duration is 2h 4m
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Skyscanner2h 8m014:28George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport16:36St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Skyscanner goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 30/12/2025 14:28:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 30/12/2025 16:36:00. 50 Economy ticket for £255 per person are available. Travel duration is 2h 8m
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United Airlines5h 57m006:30George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport12:27St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from United Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 30/12/2025 06:30:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 30/12/2025 12:27:00. 50 Economy ticket for £262 per person are available. Travel duration is 5h 57m
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Frontier Airlines27h 17m006:45George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport10:02St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Frontier Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 30/12/2025 06:45:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 31/12/2025 10:02:00. 50 Economy ticket for £267 per person are available. Travel duration is 27h 17m
Cheapest Buses Tuesday
Cheapest Flights Tuesday
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Spirit Airlines24h 48m010:08George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport10:56St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Spirit Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 31/12/2025 10:08:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 01/01/2026 10:56:00. 50 Economy ticket for £178 per person are available. Travel duration is 24h 48m
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Spirit Airlines16h 1m018:55George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport10:56St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Spirit Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 31/12/2025 18:55:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 01/01/2026 10:56:00. 50 Economy ticket for £178 per person are available. Travel duration is 16h 1m
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United Airlines19h 46m018:40George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport14:26St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from United Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 31/12/2025 18:40:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 01/01/2026 14:26:00. 50 Economy ticket for £187 per person are available. Travel duration is 19h 46m
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United Airlines18h 31m019:55George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport14:26St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from United Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 31/12/2025 19:55:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 01/01/2026 14:26:00. 50 Economy ticket for £187 per person are available. Travel duration is 18h 31m
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Frontier Airlines15h 35m018:05George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport09:40St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Frontier Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 31/12/2025 18:05:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 01/01/2026 09:40:00. 50 Economy ticket for £225 per person are available. Travel duration is 15h 35m
Cheapest Flights Wednesday
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Greyhound Lines Mexico37h 20m009:30HoustonSW Agencia Autobuses22:50St. Louis, MOGateway Station0EconomyA Bus from Greyhound Lines Mexico goes from SW Agencia Autobuses, Houston (USA) at 01/01/2026 09:30:00 to Gateway Station, St. Louis, MO (USA) arriving at 02/01/2026 22:50:00. 50 Economy ticket for £117 per person are available. Travel duration is 37h 20m
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Greyhound US23h 10m013:45HoustonHarrisburg Blvd Station12:55St. Louis, MOGateway Station0EconomyA Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 01/01/2026 13:45:00 to Gateway Station, St. Louis, MO (USA) arriving at 02/01/2026 12:55:00. 50 Economy ticket for £118 per person are available. Travel duration is 23h 10m
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Greyhound US27h 55m018:55HoustonHarrisburg Blvd Station22:50St. Louis, MOGateway Station0EconomyA Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 01/01/2026 18:55:00 to Gateway Station, St. Louis, MO (USA) arriving at 02/01/2026 22:50:00. 50 Economy ticket for £118 per person are available. Travel duration is 27h 55m
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FlixBus22h 40m017:05HoustonDowntown Houston15:45St. Louis, MOGateway Station0EconomyA Bus from FlixBus goes from Downtown Houston, Houston (USA) at 01/01/2026 17:05:00 to Gateway Station, St. Louis, MO (USA) arriving at 02/01/2026 15:45:00. 50 Economy ticket for £118 per person are available. Travel duration is 22h 40m
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Valley Transit30h 20m006:35HoustonSW Agencia Autobuses12:55St. Louis, MOGateway Station0EconomyA Bus from Valley Transit goes from SW Agencia Autobuses, Houston (USA) at 01/01/2026 06:35:00 to Gateway Station, St. Louis, MO (USA) arriving at 02/01/2026 12:55:00. 50 Economy ticket for £119 per person are available. Travel duration is 30h 20m
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Frontier Airlines12h 11m021:34George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport09:45St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Frontier Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 01/01/2026 21:34:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 02/01/2026 09:45:00. 50 Economy ticket for £230 per person are available. Travel duration is 12h 11m
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Frontier Airlines27h 17m006:45George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport10:02St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Frontier Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 01/01/2026 06:45:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 02/01/2026 10:02:00. 50 Economy ticket for £234 per person are available. Travel duration is 27h 17m
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Spirit Airlines14h 0m019:45George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport09:45St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Spirit Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 01/01/2026 19:45:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 02/01/2026 09:45:00. 50 Economy ticket for £242 per person are available. Travel duration is 14h 0m
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United Airlines6h 11m008:15George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport14:26St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from United Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 01/01/2026 08:15:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 01/01/2026 14:26:00. 50 Economy ticket for £325 per person are available. Travel duration is 6h 11m
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United Airlines4h 56m009:30George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport14:26St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from United Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 01/01/2026 09:30:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 01/01/2026 14:26:00. 50 Economy ticket for £325 per person are available. Travel duration is 4h 56m
Cheapest Buses Thursday
Cheapest Flights Thursday
What are the fastest trips from Houston to St. Louis, MO?
You can get to St. Louis, MO from Houston in just 2h 4m with a Flight from Skyscanner. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
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Skyscanner2h 4m007:45George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport09:49St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Skyscanner goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 26/12/2025 07:45:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 26/12/2025 09:49:00. 50 Economy ticket for £329 per person are available. Travel duration is 2h 4m
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United Airlines2h 5m019:50George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport21:55St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from United Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 26/12/2025 19:50:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 26/12/2025 21:55:00. 50 Economy ticket for £329 per person are available. Travel duration is 2h 5m
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Skyscanner2h 8m014:28George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport16:36St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Skyscanner goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 26/12/2025 14:28:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 26/12/2025 16:36:00. 50 Economy ticket for £329 per person are available. Travel duration is 2h 8m
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United Airlines5h 57m006:30George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport12:27St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from United Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 26/12/2025 06:30:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 26/12/2025 12:27:00. 50 Economy ticket for £336 per person are available. Travel duration is 5h 57m
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Frontier Airlines12h 7m021:55George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport10:02St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Frontier Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 26/12/2025 21:55:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 27/12/2025 10:02:00. 50 Economy ticket for £175 per person are available. Travel duration is 12h 7m
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FlixBus22h 40m017:05HoustonDowntown Houston15:45St. Louis, MOGateway Station0EconomyA Bus from FlixBus goes from Downtown Houston, Houston (USA) at 26/12/2025 17:05:00 to Gateway Station, St. Louis, MO (USA) arriving at 27/12/2025 15:45:00. 50 Economy ticket for £129 per person are available. Travel duration is 22h 40m
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Greyhound US25h 0m022:00HoustonHarrisburg Blvd Station23:00St. Louis, MOGateway Station0EconomyA Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 26/12/2025 22:00:00 to Gateway Station, St. Louis, MO (USA) arriving at 27/12/2025 23:00:00. 50 Economy ticket for £130 per person are available. Travel duration is 25h 0m
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FlixBus25h 55m013:50HoustonUptown/Upper Kirby15:45St. Louis, MOGateway Station0EconomyA Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 26/12/2025 13:50:00 to Gateway Station, St. Louis, MO (USA) arriving at 27/12/2025 15:45:00. 50 Economy ticket for £130 per person are available. Travel duration is 25h 55m
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Valley Transit30h 20m006:35HoustonSW Agencia Autobuses12:55St. Louis, MOGateway Station0EconomyA Bus from Valley Transit goes from SW Agencia Autobuses, Houston (USA) at 26/12/2025 06:35:00 to Gateway Station, St. Louis, MO (USA) arriving at 27/12/2025 12:55:00. 50 Economy ticket for £176 per person are available. Travel duration is 30h 20m
Fastest Flights Friday
Fastest Buses Friday
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Greyhound US23h 10m013:45HoustonHarrisburg Blvd Station12:55St. Louis, MOGateway Station0EconomyA Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 27/12/2025 13:45:00 to Gateway Station, St. Louis, MO (USA) arriving at 28/12/2025 12:55:00. 50 Economy ticket for £111 per person are available. Travel duration is 23h 10m
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FlixBus25h 30m011:25HoustonUptown/Upper Kirby12:55St. Louis, MOGateway Station0EconomyA Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 27/12/2025 11:25:00 to Gateway Station, St. Louis, MO (USA) arriving at 28/12/2025 12:55:00. 50 Economy ticket for £112 per person are available. Travel duration is 25h 30m
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Greyhound US27h 50m019:00HoustonHarrisburg Blvd Station22:50St. Louis, MOGateway Station0EconomyA Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 27/12/2025 19:00:00 to Gateway Station, St. Louis, MO (USA) arriving at 28/12/2025 22:50:00. 50 Economy ticket for £113 per person are available. Travel duration is 27h 50m
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FlixBus28h 50m018:00HoustonDowntown Houston22:50St. Louis, MOGateway Station0EconomyA Bus from FlixBus goes from Downtown Houston, Houston (USA) at 27/12/2025 18:00:00 to Gateway Station, St. Louis, MO (USA) arriving at 28/12/2025 22:50:00. 50 Economy ticket for £111 per person are available. Travel duration is 28h 50m
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Greyhound Lines Mexico37h 20m009:30HoustonSW Agencia Autobuses22:50St. Louis, MOGateway Station0EconomyA Bus from Greyhound Lines Mexico goes from SW Agencia Autobuses, Houston (USA) at 27/12/2025 09:30:00 to Gateway Station, St. Louis, MO (USA) arriving at 28/12/2025 22:50:00. 50 Economy ticket for £112 per person are available. Travel duration is 37h 20m
Fastest Buses Saturday
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Skyscanner2h 4m007:45George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport09:49St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Skyscanner goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 28/12/2025 07:45:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 28/12/2025 09:49:00. 50 Economy ticket for £255 per person are available. Travel duration is 2h 4m
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United Airlines2h 5m019:50George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport21:55St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from United Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 28/12/2025 19:50:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 28/12/2025 21:55:00. 50 Economy ticket for £254 per person are available. Travel duration is 2h 5m
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Frontier Airlines12h 11m021:34George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport09:45St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Frontier Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 28/12/2025 21:34:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 29/12/2025 09:45:00. 50 Economy ticket for £153 per person are available. Travel duration is 12h 11m
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Frontier Airlines30h 53m014:32George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport21:25St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Frontier Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 28/12/2025 14:32:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 29/12/2025 21:25:00. 50 Economy ticket for £241 per person are available. Travel duration is 30h 53m
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FlixBus22h 40m017:05HoustonDowntown Houston15:45St. Louis, MOGateway Station0EconomyA Bus from FlixBus goes from Downtown Houston, Houston (USA) at 28/12/2025 17:05:00 to Gateway Station, St. Louis, MO (USA) arriving at 29/12/2025 15:45:00. 50 Economy ticket for £127 per person are available. Travel duration is 22h 40m
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Greyhound US23h 10m013:45HoustonHarrisburg Blvd Station12:55St. Louis, MOGateway Station0EconomyA Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 28/12/2025 13:45:00 to Gateway Station, St. Louis, MO (USA) arriving at 29/12/2025 12:55:00. 50 Economy ticket for £134 per person are available. Travel duration is 23h 10m
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Greyhound US27h 55m018:55HoustonHarrisburg Blvd Station22:50St. Louis, MOGateway Station0EconomyA Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 28/12/2025 18:55:00 to Gateway Station, St. Louis, MO (USA) arriving at 29/12/2025 22:50:00. 50 Economy ticket for £131 per person are available. Travel duration is 27h 55m
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FlixBus30h 20m006:35HoustonSW Agencia Autobuses12:55St. Louis, MOGateway Station0EconomyA Bus from FlixBus goes from SW Agencia Autobuses, Houston (USA) at 28/12/2025 06:35:00 to Gateway Station, St. Louis, MO (USA) arriving at 29/12/2025 12:55:00. 50 Economy ticket for £131 per person are available. Travel duration is 30h 20m
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Valley Transit30h 20m006:35HoustonSW Agencia Autobuses12:55St. Louis, MOGateway Station0EconomyA Bus from Valley Transit goes from SW Agencia Autobuses, Houston (USA) at 28/12/2025 06:35:00 to Gateway Station, St. Louis, MO (USA) arriving at 29/12/2025 12:55:00. 50 Economy ticket for £135 per person are available. Travel duration is 30h 20m
Fastest Flights Sunday
Fastest Buses Sunday
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United Airlines7h 27m005:00George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport12:27St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from United Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 29/12/2025 05:00:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 29/12/2025 12:27:00. 50 Economy ticket for £261 per person are available. Travel duration is 7h 27m
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Frontier Airlines15h 35m018:05George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport09:40St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Frontier Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 29/12/2025 18:05:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 30/12/2025 09:40:00. 50 Economy ticket for £219 per person are available. Travel duration is 15h 35m
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Spirit Airlines16h 47m005:46George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport22:33St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Spirit Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 29/12/2025 05:46:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 29/12/2025 22:33:00. 50 Economy ticket for £247 per person are available. Travel duration is 16h 47m
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Spirit Airlines18h 31m015:09George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport09:40St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Spirit Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 29/12/2025 15:09:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 30/12/2025 09:40:00. 50 Economy ticket for £238 per person are available. Travel duration is 18h 31m
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Frontier Airlines27h 40m006:00George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport09:40St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Frontier Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 29/12/2025 06:00:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 30/12/2025 09:40:00. 50 Economy ticket for £223 per person are available. Travel duration is 27h 40m
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Greyhound US21h 0m001:50HoustonHarrisburg Blvd Station22:50St. Louis, MOGateway Station0EconomyA Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 29/12/2025 01:50:00 to Gateway Station, St. Louis, MO (USA) arriving at 29/12/2025 22:50:00. 50 Economy ticket for £120 per person are available. Travel duration is 21h 0m
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FlixBus22h 15m008:55HoustonUptown/Upper Kirby07:10St. Louis, MOGateway Station0EconomyA Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 29/12/2025 08:55:00 to Gateway Station, St. Louis, MO (USA) arriving at 30/12/2025 07:10:00. 50 Economy ticket for £120 per person are available. Travel duration is 22h 15m
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FlixBus22h 40m017:05HoustonDowntown Houston15:45St. Louis, MOGateway Station0EconomyA Bus from FlixBus goes from Downtown Houston, Houston (USA) at 29/12/2025 17:05:00 to Gateway Station, St. Louis, MO (USA) arriving at 30/12/2025 15:45:00. 50 Economy ticket for £119 per person are available. Travel duration is 22h 40m
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Greyhound US23h 10m013:45HoustonHarrisburg Blvd Station12:55St. Louis, MOGateway Station0EconomyA Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 29/12/2025 13:45:00 to Gateway Station, St. Louis, MO (USA) arriving at 30/12/2025 12:55:00. 50 Economy ticket for £119 per person are available. Travel duration is 23h 10m
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Valley Transit30h 20m006:35HoustonSW Agencia Autobuses12:55St. Louis, MOGateway Station0EconomyA Bus from Valley Transit goes from SW Agencia Autobuses, Houston (USA) at 29/12/2025 06:35:00 to Gateway Station, St. Louis, MO (USA) arriving at 30/12/2025 12:55:00. 50 Economy ticket for £120 per person are available. Travel duration is 30h 20m
Fastest Flights Monday
Fastest Buses Monday
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Skyscanner2h 4m007:45George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport09:49St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Skyscanner goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 30/12/2025 07:45:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 30/12/2025 09:49:00. 50 Economy ticket for £255 per person are available. Travel duration is 2h 4m
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United Airlines2h 5m019:50George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport21:55St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from United Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 30/12/2025 19:50:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 30/12/2025 21:55:00. 50 Economy ticket for £255 per person are available. Travel duration is 2h 5m
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Skyscanner2h 8m014:28George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport16:36St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Skyscanner goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 30/12/2025 14:28:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 30/12/2025 16:36:00. 50 Economy ticket for £255 per person are available. Travel duration is 2h 8m
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United Airlines5h 57m006:30George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport12:27St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from United Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 30/12/2025 06:30:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 30/12/2025 12:27:00. 50 Economy ticket for £262 per person are available. Travel duration is 5h 57m
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Frontier Airlines27h 17m006:45George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport10:02St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Frontier Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 30/12/2025 06:45:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 31/12/2025 10:02:00. 50 Economy ticket for £267 per person are available. Travel duration is 27h 17m
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Greyhound US23h 10m013:45HoustonHarrisburg Blvd Station12:55St. Louis, MOGateway Station0EconomyA Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 30/12/2025 13:45:00 to Gateway Station, St. Louis, MO (USA) arriving at 31/12/2025 12:55:00. 50 Economy ticket for £127 per person are available. Travel duration is 23h 10m
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FlixBus27h 0m019:50HoustonUptown/Upper Kirby22:50St. Louis, MOGateway Station0EconomyA Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 30/12/2025 19:50:00 to Gateway Station, St. Louis, MO (USA) arriving at 31/12/2025 22:50:00. 50 Economy ticket for £127 per person are available. Travel duration is 27h 0m
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FlixBus27h 15m019:35HoustonDowntown Houston22:50St. Louis, MOGateway Station0EconomyA Bus from FlixBus goes from Downtown Houston, Houston (USA) at 30/12/2025 19:35:00 to Gateway Station, St. Louis, MO (USA) arriving at 31/12/2025 22:50:00. 50 Economy ticket for £127 per person are available. Travel duration is 27h 15m
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Greyhound US27h 55m018:55HoustonHarrisburg Blvd Station22:50St. Louis, MOGateway Station0EconomyA Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 30/12/2025 18:55:00 to Gateway Station, St. Louis, MO (USA) arriving at 31/12/2025 22:50:00. 50 Economy ticket for £127 per person are available. Travel duration is 27h 55m
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Valley Transit30h 20m006:35HoustonSW Agencia Autobuses12:55St. Louis, MOGateway Station0EconomyA Bus from Valley Transit goes from SW Agencia Autobuses, Houston (USA) at 30/12/2025 06:35:00 to Gateway Station, St. Louis, MO (USA) arriving at 31/12/2025 12:55:00. 50 Economy ticket for £128 per person are available. Travel duration is 30h 20m
Fastest Flights Tuesday
Fastest Buses Tuesday
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Frontier Airlines15h 35m018:05George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport09:40St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Frontier Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 31/12/2025 18:05:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 01/01/2026 09:40:00. 50 Economy ticket for £225 per person are available. Travel duration is 15h 35m
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Spirit Airlines16h 1m018:55George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport10:56St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Spirit Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 31/12/2025 18:55:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 01/01/2026 10:56:00. 50 Economy ticket for £178 per person are available. Travel duration is 16h 1m
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United Airlines18h 31m019:55George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport14:26St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from United Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 31/12/2025 19:55:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 01/01/2026 14:26:00. 50 Economy ticket for £187 per person are available. Travel duration is 18h 31m
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United Airlines19h 46m018:40George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport14:26St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from United Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 31/12/2025 18:40:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 01/01/2026 14:26:00. 50 Economy ticket for £187 per person are available. Travel duration is 19h 46m
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Spirit Airlines24h 48m010:08George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport10:56St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Spirit Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 31/12/2025 10:08:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 01/01/2026 10:56:00. 50 Economy ticket for £178 per person are available. Travel duration is 24h 48m
Fastest Flights Wednesday
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United Airlines4h 56m009:30George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport14:26St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from United Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 01/01/2026 09:30:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 01/01/2026 14:26:00. 50 Economy ticket for £325 per person are available. Travel duration is 4h 56m
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United Airlines6h 11m008:15George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport14:26St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from United Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 01/01/2026 08:15:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 01/01/2026 14:26:00. 50 Economy ticket for £325 per person are available. Travel duration is 6h 11m
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Frontier Airlines12h 11m021:34George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport09:45St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Frontier Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 01/01/2026 21:34:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 02/01/2026 09:45:00. 50 Economy ticket for £230 per person are available. Travel duration is 12h 11m
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Spirit Airlines14h 0m019:45George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport09:45St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Spirit Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 01/01/2026 19:45:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 02/01/2026 09:45:00. 50 Economy ticket for £242 per person are available. Travel duration is 14h 0m
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Frontier Airlines27h 17m006:45George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport10:02St. Louis Lambert AirportSt. Louis Lambert Airport0EconomyA Flight from Frontier Airlines goes from George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) at 01/01/2026 06:45:00 to St. Louis Lambert Airport, St. Louis Lambert Airport (USA) arriving at 02/01/2026 10:02:00. 50 Economy ticket for £234 per person are available. Travel duration is 27h 17m
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FlixBus22h 40m017:05HoustonDowntown Houston15:45St. Louis, MOGateway Station0EconomyA Bus from FlixBus goes from Downtown Houston, Houston (USA) at 01/01/2026 17:05:00 to Gateway Station, St. Louis, MO (USA) arriving at 02/01/2026 15:45:00. 50 Economy ticket for £118 per person are available. Travel duration is 22h 40m
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Greyhound US23h 10m013:45HoustonHarrisburg Blvd Station12:55St. Louis, MOGateway Station0EconomyA Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 01/01/2026 13:45:00 to Gateway Station, St. Louis, MO (USA) arriving at 02/01/2026 12:55:00. 50 Economy ticket for £118 per person are available. Travel duration is 23h 10m
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Greyhound US27h 55m018:55HoustonHarrisburg Blvd Station22:50St. Louis, MOGateway Station0EconomyA Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 01/01/2026 18:55:00 to Gateway Station, St. Louis, MO (USA) arriving at 02/01/2026 22:50:00. 50 Economy ticket for £118 per person are available. Travel duration is 27h 55m
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Valley Transit30h 20m006:35HoustonSW Agencia Autobuses12:55St. Louis, MOGateway Station0EconomyA Bus from Valley Transit goes from SW Agencia Autobuses, Houston (USA) at 01/01/2026 06:35:00 to Gateway Station, St. Louis, MO (USA) arriving at 02/01/2026 12:55:00. 50 Economy ticket for £119 per person are available. Travel duration is 30h 20m
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Greyhound Lines Mexico37h 20m009:30HoustonSW Agencia Autobuses22:50St. Louis, MOGateway Station0EconomyA Bus from Greyhound Lines Mexico goes from SW Agencia Autobuses, Houston (USA) at 01/01/2026 09:30:00 to Gateway Station, St. Louis, MO (USA) arriving at 02/01/2026 22:50:00. 50 Economy ticket for £117 per person are available. Travel duration is 37h 20m
Fastest Flights Thursday
Fastest Buses Thursday
Here you will find all operators and timetables for a
Bus from Houston to St. Louis, MO
What are the most popular stations in Houston and St. Louis, MO?
In Houston, you will usually depart from Hillcroft METRO Park and Ride Coach Station, Lockwood or Main St & Airline Dr, while in St. Louis, MO you will be arriving at Gateway Station, Lindbergh @ Hackberry NB Bus Stop or Skinker Boulevard, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to St. Louis, MO from Houston? With 8 connections between 5 Bus and Flight operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Houston and St. Louis, MO, you can pay as low as £111 with a Bus from Greyhound US.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Skyscanner: you will get to St. Louis, MO in just 2h 4m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Houston and St. Louis, MO are Greyhound US, FlixBus and United Airlines, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Houston and St. Louis, MO is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from West University Place, TX or to Sauget, IL, and look at flights from William P. Hobby Airport, and landing at St. Louis Lambert Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Houston to St. Louis, MO?
The most popular companies between Houston and St. Louis, MO, are Greyhound US, FlixBus and United Airlines. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: Greyhound US, FlixBus, Valley Transit and 1 more.
Airlines: United Airlines, Frontier Airlines, Skyscanner and 1 more.
All you need to know when you travel from Houston to St. Louis, MO
Check all information on comfort and services on all modes of transports from Houston to St. Louis, MO. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Houston to St. Louis, MO
How can I reach St. Louis, MO from Houston?
Every day, there are on average 8 connections between Bus and Flight, with which you can get to St. Louis, MO from Houston.
How far is St. Louis, MO from Houston?
The distance between Houston and St. Louis, MO is 1,094.8 km.
What is the most ecofriendly mode of transport between Houston and St. Louis, MO?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 30 kgs of CO2, a train 38 kgs, a car 186 kgs, and a flight 269 kgs.
What is the cheapest mode of transport from Houston to St. Louis, MO?
You can get to St. Louis, MO with just £111 by taking a Bus from Greyhound US.
What is the fastest way to get from Houston to St. Louis, MO?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to St. Louis, MO in just 2h 4m with a Flight from Skyscanner.
More routes to Houston and to St. Louis, MO
Looking for more options? Here you can see the most popular routes to Houston and to St. Louis, MO. Simply click on a connection, and you’ll find all the details about the route!
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