What is the best way to travel from Lyon to Karlsruhe?
Looking for a trip? Check and compare all the available Trains and Buses to Karlsruhe from Lyon. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 2 available companies to find your perfect trip!
What is the cheapest way to reach Karlsruhe from Lyon?
You can reach Karlsruhe with just £22 by taking a Bus from FlixBus, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
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FlixBus9h 10m023:00LyonLyon Avenue Tony Garnier Coach Stop08:10KarlsruheCentral Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 10/03/2026 23:00:00 to Central Station, Karlsruhe (Germany) arriving at 11/03/2026 08:10:00. 50 Economy ticket for £25 per person are available. Travel duration is 9h 10m
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FlixBus7h 55m005:20LyonLyon Avenue Tony Garnier Coach Stop13:15KarlsruheCentral Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 10/03/2026 05:20:00 to Central Station, Karlsruhe (Germany) arriving at 10/03/2026 13:15:00. 50 Economy ticket for £28 per person are available. Travel duration is 7h 55m
Cheapest Buses Tuesday
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FlixBus17h 25m014:55LyonLyon Avenue Tony Garnier Coach Stop08:20KarlsruheCentral Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 11/03/2026 14:55:00 to Central Station, Karlsruhe (Germany) arriving at 12/03/2026 08:20:00. 50 Economy ticket for £23 per person are available. Travel duration is 17h 25m
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FlixBus15h 50m016:40LyonLyon Avenue Tony Garnier Coach Stop08:30KarlsruheCentral Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 11/03/2026 16:40:00 to Central Station, Karlsruhe (Germany) arriving at 12/03/2026 08:30:00. 50 Economy ticket for £23 per person are available. Travel duration is 15h 50m
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FlixBus17h 35m008:35LyonLyon Avenue Tony Garnier Coach Stop02:10KarlsruheCentral Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 11/03/2026 08:35:00 to Central Station, Karlsruhe (Germany) arriving at 12/03/2026 02:10:00. 50 Economy ticket for £24 per person are available. Travel duration is 17h 35m
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FlixBus14h 5m013:05LyonLyon Avenue Tony Garnier Coach Stop03:10KarlsruheCentral Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 11/03/2026 13:05:00 to Central Station, Karlsruhe (Germany) arriving at 12/03/2026 03:10:00. 50 Economy ticket for £29 per person are available. Travel duration is 14h 5m
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FlixBus17h 25m000:50LyonLyon Avenue Tony Garnier Coach Stop18:15KarlsruheCentral Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 11/03/2026 00:50:00 to Central Station, Karlsruhe (Germany) arriving at 11/03/2026 18:15:00. 50 Economy ticket for £32 per person are available. Travel duration is 17h 25m
Cheapest Buses Wednesday
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FlixBus8h 20m022:00LyonLyon Avenue Tony Garnier Coach Stop06:20KarlsruheCentral Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 12/03/2026 22:00:00 to Central Station, Karlsruhe (Germany) arriving at 13/03/2026 06:20:00. 50 Economy ticket for £22 per person are available. Travel duration is 8h 20m
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FlixBus10h 20m007:20LyonLyon Avenue Tony Garnier Coach Stop17:40KarlsruheCentral Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 12/03/2026 07:20:00 to Central Station, Karlsruhe (Germany) arriving at 12/03/2026 17:40:00. 50 Economy ticket for £23 per person are available. Travel duration is 10h 20m
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FlixBus11h 30m018:15LyonLyon Avenue Tony Garnier Coach Stop05:45KarlsruheCentral Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 12/03/2026 18:15:00 to Central Station, Karlsruhe (Germany) arriving at 13/03/2026 05:45:00. 50 Economy ticket for £36 per person are available. Travel duration is 11h 30m
Cheapest Buses Thursday
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FlixBus7h 55m005:20LyonLyon Avenue Tony Garnier Coach Stop13:15KarlsruheCentral Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 15/03/2026 05:20:00 to Central Station, Karlsruhe (Germany) arriving at 15/03/2026 13:15:00. 50 Economy ticket for £25 per person are available. Travel duration is 7h 55m
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FlixBus8h 45m017:05LyonLyon Avenue Tony Garnier Coach Stop01:50KarlsruheCentral Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 15/03/2026 17:05:00 to Central Station, Karlsruhe (Germany) arriving at 16/03/2026 01:50:00. 50 Economy ticket for £25 per person are available. Travel duration is 8h 45m
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FlixBus8h 20m022:00LyonLyon Avenue Tony Garnier Coach Stop06:20KarlsruheCentral Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 15/03/2026 22:00:00 to Central Station, Karlsruhe (Germany) arriving at 16/03/2026 06:20:00. 50 Economy ticket for £25 per person are available. Travel duration is 8h 20m
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FlixBus10h 20m007:20LyonLyon Avenue Tony Garnier Coach Stop17:40KarlsruheCentral Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 15/03/2026 07:20:00 to Central Station, Karlsruhe (Germany) arriving at 15/03/2026 17:40:00. 50 Economy ticket for £26 per person are available. Travel duration is 10h 20m
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FlixBus9h 10m023:00LyonLyon Avenue Tony Garnier Coach Stop08:10KarlsruheCentral Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 15/03/2026 23:00:00 to Central Station, Karlsruhe (Germany) arriving at 16/03/2026 08:10:00. 50 Economy ticket for £26 per person are available. Travel duration is 9h 10m
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TGV Lyria5h 34m009:16LyonPart-Dieu Train Station14:50KarlsruheCentral Station0EconomyA Train from TGV Lyria goes from Part-Dieu Train Station, Lyon (France) at 15/03/2026 09:16:00 to Central Station, Karlsruhe (Germany) arriving at 15/03/2026 14:50:00. 50 Economy ticket for £76 per person are available. Travel duration is 5h 34m
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TGV Lyria5h 21m011:04LyonPart-Dieu Train Station16:25KarlsruheCentral Station0EconomyA Train from TGV Lyria goes from Part-Dieu Train Station, Lyon (France) at 15/03/2026 11:04:00 to Central Station, Karlsruhe (Germany) arriving at 15/03/2026 16:25:00. 50 Economy ticket for £167 per person are available. Travel duration is 5h 21m
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TGV Lyria5h 21m013:04LyonPart-Dieu Train Station18:25KarlsruheCentral Station0EconomyA Train from TGV Lyria goes from Part-Dieu Train Station, Lyon (France) at 15/03/2026 13:04:00 to Central Station, Karlsruhe (Germany) arriving at 15/03/2026 18:25:00. 50 Economy ticket for £169 per person are available. Travel duration is 5h 21m
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TGV Lyria5h 52m012:00LyonPart-Dieu Train Station17:52KarlsruheCentral Station0EconomyA Train from TGV Lyria goes from Part-Dieu Train Station, Lyon (France) at 15/03/2026 12:00:00 to Central Station, Karlsruhe (Germany) arriving at 15/03/2026 17:52:00. 50 Economy ticket for £184 per person are available. Travel duration is 5h 52m
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TGV Lyria5h 21m015:04LyonPart-Dieu Train Station20:25KarlsruheCentral Station0EconomyA Train from TGV Lyria goes from Part-Dieu Train Station, Lyon (France) at 15/03/2026 15:04:00 to Central Station, Karlsruhe (Germany) arriving at 15/03/2026 20:25:00. 50 Economy ticket for £207 per person are available. Travel duration is 5h 21m
Cheapest Buses Sunday
Cheapest Trains Sunday
What are the fastest trips from Lyon to Karlsruhe?
You can get to Karlsruhe from Lyon in just 5h 21m with a Train from TGV Lyria. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
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FlixBus7h 55m005:20LyonLyon Avenue Tony Garnier Coach Stop13:15KarlsruheCentral Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 10/03/2026 05:20:00 to Central Station, Karlsruhe (Germany) arriving at 10/03/2026 13:15:00. 50 Economy ticket for £28 per person are available. Travel duration is 7h 55m
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FlixBus9h 10m023:00LyonLyon Avenue Tony Garnier Coach Stop08:10KarlsruheCentral Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 10/03/2026 23:00:00 to Central Station, Karlsruhe (Germany) arriving at 11/03/2026 08:10:00. 50 Economy ticket for £25 per person are available. Travel duration is 9h 10m
Fastest Buses Tuesday
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FlixBus14h 5m013:05LyonLyon Avenue Tony Garnier Coach Stop03:10KarlsruheCentral Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 11/03/2026 13:05:00 to Central Station, Karlsruhe (Germany) arriving at 12/03/2026 03:10:00. 50 Economy ticket for £29 per person are available. Travel duration is 14h 5m
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FlixBus15h 50m016:40LyonLyon Avenue Tony Garnier Coach Stop08:30KarlsruheCentral Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 11/03/2026 16:40:00 to Central Station, Karlsruhe (Germany) arriving at 12/03/2026 08:30:00. 50 Economy ticket for £23 per person are available. Travel duration is 15h 50m
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FlixBus17h 25m014:55LyonLyon Avenue Tony Garnier Coach Stop08:20KarlsruheCentral Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 11/03/2026 14:55:00 to Central Station, Karlsruhe (Germany) arriving at 12/03/2026 08:20:00. 50 Economy ticket for £23 per person are available. Travel duration is 17h 25m
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FlixBus17h 25m000:50LyonLyon Avenue Tony Garnier Coach Stop18:15KarlsruheCentral Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 11/03/2026 00:50:00 to Central Station, Karlsruhe (Germany) arriving at 11/03/2026 18:15:00. 50 Economy ticket for £32 per person are available. Travel duration is 17h 25m
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FlixBus17h 35m008:35LyonLyon Avenue Tony Garnier Coach Stop02:10KarlsruheCentral Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 11/03/2026 08:35:00 to Central Station, Karlsruhe (Germany) arriving at 12/03/2026 02:10:00. 50 Economy ticket for £24 per person are available. Travel duration is 17h 35m
Fastest Buses Wednesday
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FlixBus8h 20m022:00LyonLyon Avenue Tony Garnier Coach Stop06:20KarlsruheCentral Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 12/03/2026 22:00:00 to Central Station, Karlsruhe (Germany) arriving at 13/03/2026 06:20:00. 50 Economy ticket for £22 per person are available. Travel duration is 8h 20m
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FlixBus10h 20m007:20LyonLyon Avenue Tony Garnier Coach Stop17:40KarlsruheCentral Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 12/03/2026 07:20:00 to Central Station, Karlsruhe (Germany) arriving at 12/03/2026 17:40:00. 50 Economy ticket for £23 per person are available. Travel duration is 10h 20m
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FlixBus11h 30m018:15LyonLyon Avenue Tony Garnier Coach Stop05:45KarlsruheCentral Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 12/03/2026 18:15:00 to Central Station, Karlsruhe (Germany) arriving at 13/03/2026 05:45:00. 50 Economy ticket for £36 per person are available. Travel duration is 11h 30m
Fastest Buses Thursday
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TGV Lyria5h 21m011:04LyonPart-Dieu Train Station16:25KarlsruheCentral Station0EconomyA Train from TGV Lyria goes from Part-Dieu Train Station, Lyon (France) at 15/03/2026 11:04:00 to Central Station, Karlsruhe (Germany) arriving at 15/03/2026 16:25:00. 50 Economy ticket for £167 per person are available. Travel duration is 5h 21m
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TGV Lyria5h 21m013:04LyonPart-Dieu Train Station18:25KarlsruheCentral Station0EconomyA Train from TGV Lyria goes from Part-Dieu Train Station, Lyon (France) at 15/03/2026 13:04:00 to Central Station, Karlsruhe (Germany) arriving at 15/03/2026 18:25:00. 50 Economy ticket for £169 per person are available. Travel duration is 5h 21m
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TGV Lyria5h 21m015:04LyonPart-Dieu Train Station20:25KarlsruheCentral Station0EconomyA Train from TGV Lyria goes from Part-Dieu Train Station, Lyon (France) at 15/03/2026 15:04:00 to Central Station, Karlsruhe (Germany) arriving at 15/03/2026 20:25:00. 50 Economy ticket for £207 per person are available. Travel duration is 5h 21m
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TGV Lyria5h 34m009:16LyonPart-Dieu Train Station14:50KarlsruheCentral Station0EconomyA Train from TGV Lyria goes from Part-Dieu Train Station, Lyon (France) at 15/03/2026 09:16:00 to Central Station, Karlsruhe (Germany) arriving at 15/03/2026 14:50:00. 50 Economy ticket for £76 per person are available. Travel duration is 5h 34m
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TGV Lyria5h 52m012:00LyonPart-Dieu Train Station17:52KarlsruheCentral Station0EconomyA Train from TGV Lyria goes from Part-Dieu Train Station, Lyon (France) at 15/03/2026 12:00:00 to Central Station, Karlsruhe (Germany) arriving at 15/03/2026 17:52:00. 50 Economy ticket for £184 per person are available. Travel duration is 5h 52m
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FlixBus7h 55m005:20LyonLyon Avenue Tony Garnier Coach Stop13:15KarlsruheCentral Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 15/03/2026 05:20:00 to Central Station, Karlsruhe (Germany) arriving at 15/03/2026 13:15:00. 50 Economy ticket for £25 per person are available. Travel duration is 7h 55m
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FlixBus8h 20m022:00LyonLyon Avenue Tony Garnier Coach Stop06:20KarlsruheCentral Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 15/03/2026 22:00:00 to Central Station, Karlsruhe (Germany) arriving at 16/03/2026 06:20:00. 50 Economy ticket for £25 per person are available. Travel duration is 8h 20m
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FlixBus8h 45m017:05LyonLyon Avenue Tony Garnier Coach Stop01:50KarlsruheCentral Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 15/03/2026 17:05:00 to Central Station, Karlsruhe (Germany) arriving at 16/03/2026 01:50:00. 50 Economy ticket for £25 per person are available. Travel duration is 8h 45m
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FlixBus9h 10m023:00LyonLyon Avenue Tony Garnier Coach Stop08:10KarlsruheCentral Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 15/03/2026 23:00:00 to Central Station, Karlsruhe (Germany) arriving at 16/03/2026 08:10:00. 50 Economy ticket for £26 per person are available. Travel duration is 9h 10m
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FlixBus10h 20m007:20LyonLyon Avenue Tony Garnier Coach Stop17:40KarlsruheCentral Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 15/03/2026 07:20:00 to Central Station, Karlsruhe (Germany) arriving at 15/03/2026 17:40:00. 50 Economy ticket for £26 per person are available. Travel duration is 10h 20m
Fastest Trains Sunday
Fastest Buses Sunday
Here you will find all operators and timetables for a
Bus from Lyon to Karlsruhe
What are the most popular stations in Lyon and Karlsruhe?
In Lyon, you will usually depart from Perrache Bus Stop, Perrache Train Station or Part-Dieu Train Station, while in Karlsruhe you will be arriving at Tullastraße / Verkehrsbetriebe Train Station, Heidehof Train Station or Central Station, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Karlsruhe from Lyon? With 5 connections between 2 Train and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Lyon and Karlsruhe, you can pay as low as £22 with a Bus from FlixBus.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Train from TGV Lyria: you will get to Karlsruhe in just 5h 21m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Lyon and Karlsruhe are FlixBus and TGV Lyria, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Lyon and Karlsruhe is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Caluire-et-Cuire or to Ettlingen, and look at flights from Lyons St. Exupery Airport, and landing at Karlsruhe/Baden-Baden Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Lyon to Karlsruhe?
The most popular companies between Lyon and Karlsruhe, are FlixBus and TGV Lyria. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: FlixBus
Train companies: TGV Lyria
All you need to know when you travel from Lyon to Karlsruhe
Check all information on comfort and services on all modes of transports from Lyon to Karlsruhe. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Lyon to Karlsruhe
How can I reach Karlsruhe from Lyon?
Every day, there are on average 5 connections between Train and Bus, with which you can get to Karlsruhe from Lyon.
How far is Karlsruhe from Lyon?
The distance between Lyon and Karlsruhe is 450.1 km.
What is the most ecofriendly mode of transport between Lyon and Karlsruhe?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 12 kgs of CO2, a train 16 kgs, a car 77 kgs, and a flight 111 kgs.
What is the cheapest mode of transport from Lyon to Karlsruhe?
You can get to Karlsruhe with just £22 by taking a Bus from FlixBus.
What is the fastest way to get from Lyon to Karlsruhe?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Karlsruhe in just 5h 21m with a Train from TGV Lyria.
More routes to Lyon and to Karlsruhe
Looking for more options? Here you can see the most popular routes to Lyon and to Karlsruhe. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Lyon
- Alicante to Lyon
- Annecy to Lyon
- Barcelona to Lyon
- Bordeaux to Lyon
- Brive-la-Gaillarde to Lyon
- Clermont-Ferrand to Lyon
- Dusseldorf to Lyon
- Geneva Airport to Lyon
- Geneva to Lyon
- Genoa to Lyon
- Lisbon to Lyon
- London to Lyon
- Marseille to Lyon
- Milan to Lyon
- Mulhouse to Lyon
- Nice to Lyon
- Paris to Lyon
- Porto to Lyon
- Prague to Lyon
- Strasbourg to Lyon
- Toulouse to Lyon
- Turin to Lyon
- Valence to Lyon
- Valencia to Lyon
- Trips to Karlsruhe
- Antwerp to Karlsruhe
- Berlin to Karlsruhe
- Braunschweig to Karlsruhe
- Dresden to Karlsruhe
- Dusseldorf to Karlsruhe
- Frankfurt am Main to Karlsruhe
- Hamburg to Karlsruhe
- Heidelberg to Karlsruhe
- Linz to Karlsruhe
- Ludwigshafen to Karlsruhe
- Madrid to Karlsruhe
- Mannheim to Karlsruhe
- Milan to Karlsruhe
- Munich to Karlsruhe
- Nuremberg to Karlsruhe
- Paris to Karlsruhe
- Pforzheim to Karlsruhe
- Stuttgart Airport to Karlsruhe
- Stuttgart to Karlsruhe
- Vienna to Karlsruhe
- Zurich to Karlsruhe
