What is the best way to travel from Karlsruhe to Lyon?
Looking for a trip? Check and compare all the available Buses, Trains and Flights to Lyon from Karlsruhe. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 3 available companies to find your perfect trip!
What is the cheapest way to reach Lyon from Karlsruhe?
You can reach Lyon with just £21 by taking a Bus from BlaBlaCar Bus, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
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Skyscanner20h 5m014:30Karlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport10:35Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Skyscanner goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 18/02/2026 14:30:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 19/02/2026 10:35:00. 50 Economy ticket for £135 per person are available. Travel duration is 20h 5m
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Skyscanner23h 10m014:30Karlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport13:40Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Skyscanner goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 18/02/2026 14:30:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 19/02/2026 13:40:00. 50 Economy ticket for £137 per person are available. Travel duration is 23h 10m
Cheapest Flights Wednesday
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BlaBlaCar Bus8h 5m021:05KarlsruheCentral Station05:10LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Central Station, Karlsruhe (Germany) at 20/02/2026 21:05:00 to Perrache Train Station, Lyon (France) arriving at 21/02/2026 05:10:00. 50 Economy ticket for £21 per person are available. Travel duration is 8h 5m
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BlaBlaCar Bus9h 30m011:15KarlsruheCentral Station20:45LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Central Station, Karlsruhe (Germany) at 20/02/2026 11:15:00 to Perrache Train Station, Lyon (France) arriving at 20/02/2026 20:45:00. 50 Economy ticket for £26 per person are available. Travel duration is 9h 30m
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TGV Lyria4h 46m015:12KarlsruheCentral Station19:58LyonPart-Dieu Train Station0EconomyA Train from TGV Lyria goes from Central Station, Karlsruhe (Germany) at 20/02/2026 15:12:00 to Part-Dieu Train Station, Lyon (France) arriving at 20/02/2026 19:58:00. 50 Economy ticket for £74 per person are available. Travel duration is 4h 46m
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TGV Lyria5h 24m011:32KarlsruheCentral Station16:56LyonPart-Dieu Train Station0EconomyA Train from TGV Lyria goes from Central Station, Karlsruhe (Germany) at 20/02/2026 11:32:00 to Part-Dieu Train Station, Lyon (France) arriving at 20/02/2026 16:56:00. 50 Economy ticket for £188 per person are available. Travel duration is 5h 24m
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TGV Lyria6h 3m009:53KarlsruheCentral Station15:56LyonPart-Dieu Train Station0EconomyA Train from TGV Lyria goes from Central Station, Karlsruhe (Germany) at 20/02/2026 09:53:00 to Part-Dieu Train Station, Lyon (France) arriving at 20/02/2026 15:56:00. 50 Economy ticket for £204 per person are available. Travel duration is 6h 3m
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Ryanair12h 5m022:30Karlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport10:35Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Ryanair goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 20/02/2026 22:30:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 21/02/2026 10:35:00. 50 Economy ticket for £112 per person are available. Travel duration is 12h 5m
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Ryanair10h 10m022:30Karlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport08:40Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Ryanair goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 20/02/2026 22:30:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 21/02/2026 08:40:00. 50 Economy ticket for £117 per person are available. Travel duration is 10h 10m
Cheapest Buses Friday
Cheapest Trains Friday
Cheapest Flights Friday
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BlaBlaCar Bus8h 5m021:05KarlsruheCentral Station05:10LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Central Station, Karlsruhe (Germany) at 22/02/2026 21:05:00 to Perrache Train Station, Lyon (France) arriving at 23/02/2026 05:10:00. 50 Economy ticket for £21 per person are available. Travel duration is 8h 5m
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BlaBlaCar Bus9h 30m011:15KarlsruheCentral Station20:45LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Central Station, Karlsruhe (Germany) at 22/02/2026 11:15:00 to Perrache Train Station, Lyon (France) arriving at 22/02/2026 20:45:00. 50 Economy ticket for £24 per person are available. Travel duration is 9h 30m
Cheapest Buses Sunday
What are the fastest trips from Karlsruhe to Lyon?
You can get to Lyon from Karlsruhe in just 4h 46m with a Train from TGV Lyria. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
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Skyscanner20h 5m014:30Karlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport10:35Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Skyscanner goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 18/02/2026 14:30:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 19/02/2026 10:35:00. 50 Economy ticket for £135 per person are available. Travel duration is 20h 5m
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Skyscanner23h 10m014:30Karlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport13:40Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Skyscanner goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 18/02/2026 14:30:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 19/02/2026 13:40:00. 50 Economy ticket for £137 per person are available. Travel duration is 23h 10m
Fastest Flights Wednesday
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TGV Lyria4h 46m015:12KarlsruheCentral Station19:58LyonPart-Dieu Train Station0EconomyA Train from TGV Lyria goes from Central Station, Karlsruhe (Germany) at 20/02/2026 15:12:00 to Part-Dieu Train Station, Lyon (France) arriving at 20/02/2026 19:58:00. 50 Economy ticket for £74 per person are available. Travel duration is 4h 46m
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TGV Lyria5h 24m011:32KarlsruheCentral Station16:56LyonPart-Dieu Train Station0EconomyA Train from TGV Lyria goes from Central Station, Karlsruhe (Germany) at 20/02/2026 11:32:00 to Part-Dieu Train Station, Lyon (France) arriving at 20/02/2026 16:56:00. 50 Economy ticket for £188 per person are available. Travel duration is 5h 24m
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TGV Lyria6h 3m009:53KarlsruheCentral Station15:56LyonPart-Dieu Train Station0EconomyA Train from TGV Lyria goes from Central Station, Karlsruhe (Germany) at 20/02/2026 09:53:00 to Part-Dieu Train Station, Lyon (France) arriving at 20/02/2026 15:56:00. 50 Economy ticket for £204 per person are available. Travel duration is 6h 3m
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BlaBlaCar Bus8h 5m021:05KarlsruheCentral Station05:10LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Central Station, Karlsruhe (Germany) at 20/02/2026 21:05:00 to Perrache Train Station, Lyon (France) arriving at 21/02/2026 05:10:00. 50 Economy ticket for £21 per person are available. Travel duration is 8h 5m
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BlaBlaCar Bus9h 30m011:15KarlsruheCentral Station20:45LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Central Station, Karlsruhe (Germany) at 20/02/2026 11:15:00 to Perrache Train Station, Lyon (France) arriving at 20/02/2026 20:45:00. 50 Economy ticket for £26 per person are available. Travel duration is 9h 30m
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Ryanair10h 10m022:30Karlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport08:40Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Ryanair goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 20/02/2026 22:30:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 21/02/2026 08:40:00. 50 Economy ticket for £117 per person are available. Travel duration is 10h 10m
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Ryanair12h 5m022:30Karlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport10:35Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Ryanair goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 20/02/2026 22:30:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 21/02/2026 10:35:00. 50 Economy ticket for £112 per person are available. Travel duration is 12h 5m
Fastest Trains Friday
Fastest Buses Friday
Fastest Flights Friday
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BlaBlaCar Bus8h 5m021:05KarlsruheCentral Station05:10LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Central Station, Karlsruhe (Germany) at 22/02/2026 21:05:00 to Perrache Train Station, Lyon (France) arriving at 23/02/2026 05:10:00. 50 Economy ticket for £21 per person are available. Travel duration is 8h 5m
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BlaBlaCar Bus9h 30m011:15KarlsruheCentral Station20:45LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Central Station, Karlsruhe (Germany) at 22/02/2026 11:15:00 to Perrache Train Station, Lyon (France) arriving at 22/02/2026 20:45:00. 50 Economy ticket for £24 per person are available. Travel duration is 9h 30m
Fastest Buses Sunday
Here you will find all operators and timetables for a
Bus from Karlsruhe to Lyon
What are the most popular stations in Karlsruhe and Lyon?
In Karlsruhe, you will usually depart from Central Station, Tullastraße / Verkehrsbetriebe Train Station or Heidehof Train Station, while in Lyon you will be arriving at Perrache Bus Stop, Perrache Train Station or Part-Dieu Train Station, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Lyon from Karlsruhe? With 3 connections between 3 Train, Bus and Flight operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Karlsruhe and Lyon, you can pay as low as £21 with a Bus from BlaBlaCar Bus.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Train from TGV Lyria: you will get to Lyon in just 4h 46m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Karlsruhe and Lyon are BlaBlaCar Bus, TGV Lyria and Skyscanner, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Karlsruhe and Lyon is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Ettlingen or to Caluire-et-Cuire, and look at flights from Karlsruhe/Baden-Baden Airport, and landing at Lyons St. Exupery Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Karlsruhe to Lyon?
The most popular companies between Karlsruhe and Lyon, are BlaBlaCar Bus, TGV Lyria and Skyscanner. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: BlaBlaCar Bus
Train companies: TGV Lyria
Airlines: Skyscanner and Ryanair
All you need to know when you travel from Karlsruhe to Lyon
Check all information on comfort and services on all modes of transports from Karlsruhe to Lyon. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Karlsruhe to Lyon
How can I reach Lyon from Karlsruhe?
Every day, there are on average 3 connections between Train, Bus and Flight, with which you can get to Lyon from Karlsruhe.
How far is Lyon from Karlsruhe?
The distance between Karlsruhe and Lyon is 450.1 km.
What is the most ecofriendly mode of transport between Karlsruhe and Lyon?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 12 kgs of CO2, a train 16 kgs, a car 77 kgs, and a flight 111 kgs.
What is the cheapest mode of transport from Karlsruhe to Lyon?
You can get to Lyon with just £21 by taking a Bus from BlaBlaCar Bus.
What is the fastest way to get from Karlsruhe to Lyon?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Lyon in just 4h 46m with a Train from TGV Lyria.
More routes to Karlsruhe and to Lyon
Looking for more options? Here you can see the most popular routes to Karlsruhe and to Lyon. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Karlsruhe
- Antwerp to Karlsruhe
- Barcelona to Karlsruhe
- Berlin to Karlsruhe
- Bremen to Karlsruhe
- Cologne/Bonn Airport to Karlsruhe
- Dresden to Karlsruhe
- Dusseldorf to Karlsruhe
- Frankfurt am Main Airport to Karlsruhe
- Frankfurt am Main to Karlsruhe
- Frankfurt Hahn Airport to Karlsruhe
- Freiburg to Karlsruhe
- Hamburg to Karlsruhe
- Heidelberg to Karlsruhe
- Mannheim to Karlsruhe
- Milan to Karlsruhe
- Munich to Karlsruhe
- Nuremberg to Karlsruhe
- Paris to Karlsruhe
- Saarbruecken to Karlsruhe
- Strasbourg to Karlsruhe
- Stuttgart Airport to Karlsruhe
- Stuttgart to Karlsruhe
- Vienna to Karlsruhe
- Zurich to Karlsruhe
- Trips to Lyon
- Angers to Lyon
- Barcelona to Lyon
- Bologna to Lyon
- Bordeaux to Lyon
- Caen to Lyon
- Clermont-Ferrand to Lyon
- Dijon to Lyon
- Frankfurt am Main to Lyon
- Geneva to Lyon
- Kehl to Lyon
- Marseille to Lyon
- Massy to Lyon
- Milan to Lyon
- Montpellier to Lyon
- Mulhouse to Lyon
- Paris to Lyon
- Poitiers to Lyon
- Prague to Lyon
- Strasbourg to Lyon
- Toulon to Lyon
- Toulouse to Lyon
- Tours to Lyon
- Venice to Lyon
- Zurich to Lyon
