What is the best way to travel from Karlsruhe to Lyon?
Looking for a trip? Check and compare all the available Buses and Flights to Lyon from Karlsruhe. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 2 available companies to find your perfect trip!
What is the cheapest way to reach Lyon from Karlsruhe?
You can reach Lyon with just £17 by taking a Bus from BlaBlaCar Bus, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
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BlaBlaCar Bus9h 25m011:15KarlsruheCentral Station20:40LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Central Station, Karlsruhe (Germany) at 12/12/2025 11:15:00 to Perrache Train Station, Lyon (France) arriving at 12/12/2025 20:40:00. 50 Economy ticket for £17 per person are available. Travel duration is 9h 25m
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BlaBlaCar Bus8h 0m021:05KarlsruheCentral Station05:05LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Central Station, Karlsruhe (Germany) at 12/12/2025 21:05:00 to Perrache Train Station, Lyon (France) arriving at 13/12/2025 05:05:00. 50 Economy ticket for £19 per person are available. Travel duration is 8h 0m
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FlixBus8h 45m004:05KarlsruheCentral Station12:50LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/12/2025 04:05:00 to Perrache Bus Stop, Lyon (France) arriving at 12/12/2025 12:50:00. 50 Economy ticket for £25 per person are available. Travel duration is 8h 45m
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FlixBus7h 55m015:20KarlsruheCentral Station23:15LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/12/2025 15:20:00 to Perrache Bus Stop, Lyon (France) arriving at 12/12/2025 23:15:00. 50 Economy ticket for £25 per person are available. Travel duration is 7h 55m
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FlixBus8h 20m023:55KarlsruheCentral Station08:15LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/12/2025 23:55:00 to Perrache Bus Stop, Lyon (France) arriving at 13/12/2025 08:15:00. 50 Economy ticket for £25 per person are available. Travel duration is 8h 20m
Cheapest Buses Friday
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FlixBus8h 45m004:05KarlsruheCentral Station12:50LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 13/12/2025 04:05:00 to Perrache Bus Stop, Lyon (France) arriving at 13/12/2025 12:50:00. 50 Economy ticket for £26 per person are available. Travel duration is 8h 45m
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FlixBus10h 10m010:25KarlsruheCentral Station20:35LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 13/12/2025 10:25:00 to Perrache Bus Stop, Lyon (France) arriving at 13/12/2025 20:35:00. 50 Economy ticket for £26 per person are available. Travel duration is 10h 10m
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FlixBus8h 20m023:55KarlsruheCentral Station08:15LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 13/12/2025 23:55:00 to Perrache Bus Stop, Lyon (France) arriving at 14/12/2025 08:15:00. 50 Economy ticket for £26 per person are available. Travel duration is 8h 20m
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FlixBus9h 35m000:55KarlsruheCentral Station10:30LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 13/12/2025 00:55:00 to Perrache Bus Stop, Lyon (France) arriving at 13/12/2025 10:30:00. 50 Economy ticket for £28 per person are available. Travel duration is 9h 35m
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FlixBus7h 55m015:20KarlsruheCentral Station23:15LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 13/12/2025 15:20:00 to Perrache Bus Stop, Lyon (France) arriving at 13/12/2025 23:15:00. 50 Economy ticket for £28 per person are available. Travel duration is 7h 55m
Cheapest Buses Saturday
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BlaBlaCar Bus8h 0m021:05KarlsruheCentral Station05:05LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Central Station, Karlsruhe (Germany) at 14/12/2025 21:05:00 to Perrache Train Station, Lyon (France) arriving at 15/12/2025 05:05:00. 50 Economy ticket for £21 per person are available. Travel duration is 8h 0m
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BlaBlaCar Bus9h 25m011:15KarlsruheCentral Station20:40LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Central Station, Karlsruhe (Germany) at 14/12/2025 11:15:00 to Perrache Train Station, Lyon (France) arriving at 14/12/2025 20:40:00. 50 Economy ticket for £24 per person are available. Travel duration is 9h 25m
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FlixBus8h 45m004:05KarlsruheCentral Station12:50LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 14/12/2025 04:05:00 to Perrache Bus Stop, Lyon (France) arriving at 14/12/2025 12:50:00. 50 Economy ticket for £33 per person are available. Travel duration is 8h 45m
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FlixBus9h 35m000:55KarlsruheCentral Station10:30LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 14/12/2025 00:55:00 to Perrache Bus Stop, Lyon (France) arriving at 14/12/2025 10:30:00. 50 Economy ticket for £34 per person are available. Travel duration is 9h 35m
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FlixBus8h 20m023:55KarlsruheCentral Station08:15LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 14/12/2025 23:55:00 to Perrache Bus Stop, Lyon (France) arriving at 15/12/2025 08:15:00. 50 Economy ticket for £34 per person are available. Travel duration is 8h 20m
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Skyscanner25h 40m016:10Karlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport17:50Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Skyscanner goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 14/12/2025 16:10:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 15/12/2025 17:50:00. 50 Economy ticket for £134 per person are available. Travel duration is 25h 40m
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LC Perú13h 15m018:45Karlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport08:00Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from LC Perú goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 14/12/2025 18:45:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 15/12/2025 08:00:00. 50 Economy ticket for £140 per person are available. Travel duration is 13h 15m
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Skyscanner10h 45m022:15Karlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport09:00Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Skyscanner goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 14/12/2025 22:15:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 15/12/2025 09:00:00. 50 Economy ticket for £149 per person are available. Travel duration is 10h 45m
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Ryanair23h 55m014:05Karlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport14:00Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Ryanair goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 14/12/2025 14:05:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 15/12/2025 14:00:00. 50 Economy ticket for £151 per person are available. Travel duration is 23h 55m
Cheapest Buses Sunday
Cheapest Flights Sunday
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FlixBus8h 45m004:05KarlsruheCentral Station12:50LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 15/12/2025 04:05:00 to Perrache Bus Stop, Lyon (France) arriving at 15/12/2025 12:50:00. 50 Economy ticket for £31 per person are available. Travel duration is 8h 45m
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FlixBus10h 10m010:25KarlsruheCentral Station20:35LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 15/12/2025 10:25:00 to Perrache Bus Stop, Lyon (France) arriving at 15/12/2025 20:35:00. 50 Economy ticket for £31 per person are available. Travel duration is 10h 10m
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FlixBus8h 20m023:55KarlsruheCentral Station08:15LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 15/12/2025 23:55:00 to Perrache Bus Stop, Lyon (France) arriving at 16/12/2025 08:15:00. 50 Economy ticket for £31 per person are available. Travel duration is 8h 20m
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FlixBus9h 35m000:55KarlsruheCentral Station10:30LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 15/12/2025 00:55:00 to Perrache Bus Stop, Lyon (France) arriving at 15/12/2025 10:30:00. 50 Economy ticket for £32 per person are available. Travel duration is 9h 35m
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FlixBus7h 55m015:20KarlsruheCentral Station23:15LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 15/12/2025 15:20:00 to Perrache Bus Stop, Lyon (France) arriving at 15/12/2025 23:15:00. 50 Economy ticket for £42 per person are available. Travel duration is 7h 55m
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Ryanair11h 25m022:25Karlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport09:50Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Ryanair goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 15/12/2025 22:25:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 16/12/2025 09:50:00. 50 Economy ticket for £81 per person are available. Travel duration is 11h 25m
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Ryanair15h 15m022:25Karlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport13:40Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Ryanair goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 15/12/2025 22:25:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 16/12/2025 13:40:00. 50 Economy ticket for £86 per person are available. Travel duration is 15h 15m
Cheapest Buses Monday
Cheapest Flights Monday
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FlixBus8h 45m004:05KarlsruheCentral Station12:50LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 17/12/2025 04:05:00 to Perrache Bus Stop, Lyon (France) arriving at 17/12/2025 12:50:00. 50 Economy ticket for £27 per person are available. Travel duration is 8h 45m
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FlixBus7h 55m015:20KarlsruheCentral Station23:15LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 17/12/2025 15:20:00 to Perrache Bus Stop, Lyon (France) arriving at 17/12/2025 23:15:00. 50 Economy ticket for £27 per person are available. Travel duration is 7h 55m
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FlixBus10h 10m010:25KarlsruheCentral Station20:35LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 17/12/2025 10:25:00 to Perrache Bus Stop, Lyon (France) arriving at 17/12/2025 20:35:00. 50 Economy ticket for £29 per person are available. Travel duration is 10h 10m
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FlixBus8h 20m023:55KarlsruheCentral Station08:15LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 17/12/2025 23:55:00 to Perrache Bus Stop, Lyon (France) arriving at 18/12/2025 08:15:00. 50 Economy ticket for £38 per person are available. Travel duration is 8h 20m
Cheapest Buses Wednesday
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FlixBus10h 10m010:25KarlsruheCentral Station20:35LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 18/12/2025 10:25:00 to Perrache Bus Stop, Lyon (France) arriving at 18/12/2025 20:35:00. 50 Economy ticket for £33 per person are available. Travel duration is 10h 10m
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FlixBus8h 45m004:05KarlsruheCentral Station12:50LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 18/12/2025 04:05:00 to Perrache Bus Stop, Lyon (France) arriving at 18/12/2025 12:50:00. 50 Economy ticket for £35 per person are available. Travel duration is 8h 45m
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FlixBus7h 55m015:20KarlsruheCentral Station23:15LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 18/12/2025 15:20:00 to Perrache Bus Stop, Lyon (France) arriving at 18/12/2025 23:15:00. 50 Economy ticket for £40 per person are available. Travel duration is 7h 55m
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FlixBus8h 20m023:55KarlsruheCentral Station08:15LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 18/12/2025 23:55:00 to Perrache Bus Stop, Lyon (France) arriving at 19/12/2025 08:15:00. 50 Economy ticket for £48 per person are available. Travel duration is 8h 20m
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Ryanair23h 35m022:55Karlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport22:30Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Ryanair goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 18/12/2025 22:55:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 19/12/2025 22:30:00. 50 Economy ticket for £98 per person are available. Travel duration is 23h 35m
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Skyscanner19h 15m015:05Karlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport10:20Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Skyscanner goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 18/12/2025 15:05:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 19/12/2025 10:20:00. 50 Economy ticket for £105 per person are available. Travel duration is 19h 15m
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Ryanair11h 25m022:55Karlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport10:20Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Ryanair goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 18/12/2025 22:55:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 19/12/2025 10:20:00. 50 Economy ticket for £106 per person are available. Travel duration is 11h 25m
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Wizz Air5h 45m016:25Karlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport22:10Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Wizz Air goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 18/12/2025 16:25:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 18/12/2025 22:10:00. 50 Economy ticket for £173 per person are available. Travel duration is 5h 45m
Cheapest Buses Thursday
Cheapest Flights Thursday
What are the fastest trips from Karlsruhe to Lyon?
You can get to Lyon from Karlsruhe in just 5h 45m with a Flight from Wizz Air. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
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FlixBus7h 55m015:20KarlsruheCentral Station23:15LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/12/2025 15:20:00 to Perrache Bus Stop, Lyon (France) arriving at 12/12/2025 23:15:00. 50 Economy ticket for £25 per person are available. Travel duration is 7h 55m
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BlaBlaCar Bus8h 0m021:05KarlsruheCentral Station05:05LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Central Station, Karlsruhe (Germany) at 12/12/2025 21:05:00 to Perrache Train Station, Lyon (France) arriving at 13/12/2025 05:05:00. 50 Economy ticket for £19 per person are available. Travel duration is 8h 0m
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FlixBus8h 20m023:55KarlsruheCentral Station08:15LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/12/2025 23:55:00 to Perrache Bus Stop, Lyon (France) arriving at 13/12/2025 08:15:00. 50 Economy ticket for £25 per person are available. Travel duration is 8h 20m
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FlixBus8h 45m004:05KarlsruheCentral Station12:50LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 12/12/2025 04:05:00 to Perrache Bus Stop, Lyon (France) arriving at 12/12/2025 12:50:00. 50 Economy ticket for £25 per person are available. Travel duration is 8h 45m
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BlaBlaCar Bus9h 25m011:15KarlsruheCentral Station20:40LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Central Station, Karlsruhe (Germany) at 12/12/2025 11:15:00 to Perrache Train Station, Lyon (France) arriving at 12/12/2025 20:40:00. 50 Economy ticket for £17 per person are available. Travel duration is 9h 25m
Fastest Buses Friday
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FlixBus7h 55m015:20KarlsruheCentral Station23:15LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 13/12/2025 15:20:00 to Perrache Bus Stop, Lyon (France) arriving at 13/12/2025 23:15:00. 50 Economy ticket for £28 per person are available. Travel duration is 7h 55m
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FlixBus8h 20m023:55KarlsruheCentral Station08:15LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 13/12/2025 23:55:00 to Perrache Bus Stop, Lyon (France) arriving at 14/12/2025 08:15:00. 50 Economy ticket for £26 per person are available. Travel duration is 8h 20m
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FlixBus8h 45m004:05KarlsruheCentral Station12:50LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 13/12/2025 04:05:00 to Perrache Bus Stop, Lyon (France) arriving at 13/12/2025 12:50:00. 50 Economy ticket for £26 per person are available. Travel duration is 8h 45m
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FlixBus9h 35m000:55KarlsruheCentral Station10:30LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 13/12/2025 00:55:00 to Perrache Bus Stop, Lyon (France) arriving at 13/12/2025 10:30:00. 50 Economy ticket for £28 per person are available. Travel duration is 9h 35m
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FlixBus10h 10m010:25KarlsruheCentral Station20:35LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 13/12/2025 10:25:00 to Perrache Bus Stop, Lyon (France) arriving at 13/12/2025 20:35:00. 50 Economy ticket for £26 per person are available. Travel duration is 10h 10m
Fastest Buses Saturday
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BlaBlaCar Bus8h 0m021:05KarlsruheCentral Station05:05LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Central Station, Karlsruhe (Germany) at 14/12/2025 21:05:00 to Perrache Train Station, Lyon (France) arriving at 15/12/2025 05:05:00. 50 Economy ticket for £21 per person are available. Travel duration is 8h 0m
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FlixBus8h 20m023:55KarlsruheCentral Station08:15LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 14/12/2025 23:55:00 to Perrache Bus Stop, Lyon (France) arriving at 15/12/2025 08:15:00. 50 Economy ticket for £34 per person are available. Travel duration is 8h 20m
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FlixBus8h 45m004:05KarlsruheCentral Station12:50LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 14/12/2025 04:05:00 to Perrache Bus Stop, Lyon (France) arriving at 14/12/2025 12:50:00. 50 Economy ticket for £33 per person are available. Travel duration is 8h 45m
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BlaBlaCar Bus9h 25m011:15KarlsruheCentral Station20:40LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Central Station, Karlsruhe (Germany) at 14/12/2025 11:15:00 to Perrache Train Station, Lyon (France) arriving at 14/12/2025 20:40:00. 50 Economy ticket for £24 per person are available. Travel duration is 9h 25m
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FlixBus9h 35m000:55KarlsruheCentral Station10:30LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 14/12/2025 00:55:00 to Perrache Bus Stop, Lyon (France) arriving at 14/12/2025 10:30:00. 50 Economy ticket for £34 per person are available. Travel duration is 9h 35m
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Skyscanner10h 45m022:15Karlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport09:00Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Skyscanner goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 14/12/2025 22:15:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 15/12/2025 09:00:00. 50 Economy ticket for £149 per person are available. Travel duration is 10h 45m
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LC Perú13h 15m018:45Karlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport08:00Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from LC Perú goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 14/12/2025 18:45:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 15/12/2025 08:00:00. 50 Economy ticket for £140 per person are available. Travel duration is 13h 15m
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Ryanair23h 55m014:05Karlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport14:00Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Ryanair goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 14/12/2025 14:05:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 15/12/2025 14:00:00. 50 Economy ticket for £151 per person are available. Travel duration is 23h 55m
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Skyscanner25h 40m016:10Karlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport17:50Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Skyscanner goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 14/12/2025 16:10:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 15/12/2025 17:50:00. 50 Economy ticket for £134 per person are available. Travel duration is 25h 40m
Fastest Buses Sunday
Fastest Flights Sunday
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FlixBus7h 55m015:20KarlsruheCentral Station23:15LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 15/12/2025 15:20:00 to Perrache Bus Stop, Lyon (France) arriving at 15/12/2025 23:15:00. 50 Economy ticket for £42 per person are available. Travel duration is 7h 55m
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FlixBus8h 20m023:55KarlsruheCentral Station08:15LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 15/12/2025 23:55:00 to Perrache Bus Stop, Lyon (France) arriving at 16/12/2025 08:15:00. 50 Economy ticket for £31 per person are available. Travel duration is 8h 20m
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FlixBus8h 45m004:05KarlsruheCentral Station12:50LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 15/12/2025 04:05:00 to Perrache Bus Stop, Lyon (France) arriving at 15/12/2025 12:50:00. 50 Economy ticket for £31 per person are available. Travel duration is 8h 45m
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FlixBus9h 35m000:55KarlsruheCentral Station10:30LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 15/12/2025 00:55:00 to Perrache Bus Stop, Lyon (France) arriving at 15/12/2025 10:30:00. 50 Economy ticket for £32 per person are available. Travel duration is 9h 35m
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FlixBus10h 10m010:25KarlsruheCentral Station20:35LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 15/12/2025 10:25:00 to Perrache Bus Stop, Lyon (France) arriving at 15/12/2025 20:35:00. 50 Economy ticket for £31 per person are available. Travel duration is 10h 10m
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Ryanair11h 25m022:25Karlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport09:50Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Ryanair goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 15/12/2025 22:25:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 16/12/2025 09:50:00. 50 Economy ticket for £81 per person are available. Travel duration is 11h 25m
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Ryanair15h 15m022:25Karlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport13:40Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Ryanair goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 15/12/2025 22:25:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 16/12/2025 13:40:00. 50 Economy ticket for £86 per person are available. Travel duration is 15h 15m
Fastest Buses Monday
Fastest Flights Monday
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FlixBus7h 55m015:20KarlsruheCentral Station23:15LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 17/12/2025 15:20:00 to Perrache Bus Stop, Lyon (France) arriving at 17/12/2025 23:15:00. 50 Economy ticket for £27 per person are available. Travel duration is 7h 55m
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FlixBus8h 20m023:55KarlsruheCentral Station08:15LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 17/12/2025 23:55:00 to Perrache Bus Stop, Lyon (France) arriving at 18/12/2025 08:15:00. 50 Economy ticket for £38 per person are available. Travel duration is 8h 20m
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FlixBus8h 45m004:05KarlsruheCentral Station12:50LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 17/12/2025 04:05:00 to Perrache Bus Stop, Lyon (France) arriving at 17/12/2025 12:50:00. 50 Economy ticket for £27 per person are available. Travel duration is 8h 45m
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FlixBus10h 10m010:25KarlsruheCentral Station20:35LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 17/12/2025 10:25:00 to Perrache Bus Stop, Lyon (France) arriving at 17/12/2025 20:35:00. 50 Economy ticket for £29 per person are available. Travel duration is 10h 10m
Fastest Buses Wednesday
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Wizz Air5h 45m016:25Karlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport22:10Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Wizz Air goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 18/12/2025 16:25:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 18/12/2025 22:10:00. 50 Economy ticket for £173 per person are available. Travel duration is 5h 45m
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Ryanair11h 25m022:55Karlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport10:20Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Ryanair goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 18/12/2025 22:55:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 19/12/2025 10:20:00. 50 Economy ticket for £106 per person are available. Travel duration is 11h 25m
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Skyscanner19h 15m015:05Karlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport10:20Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Skyscanner goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 18/12/2025 15:05:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 19/12/2025 10:20:00. 50 Economy ticket for £105 per person are available. Travel duration is 19h 15m
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Ryanair23h 35m022:55Karlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport22:30Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Ryanair goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 18/12/2025 22:55:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 19/12/2025 22:30:00. 50 Economy ticket for £98 per person are available. Travel duration is 23h 35m
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FlixBus7h 55m015:20KarlsruheCentral Station23:15LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 18/12/2025 15:20:00 to Perrache Bus Stop, Lyon (France) arriving at 18/12/2025 23:15:00. 50 Economy ticket for £40 per person are available. Travel duration is 7h 55m
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FlixBus8h 20m023:55KarlsruheCentral Station08:15LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 18/12/2025 23:55:00 to Perrache Bus Stop, Lyon (France) arriving at 19/12/2025 08:15:00. 50 Economy ticket for £48 per person are available. Travel duration is 8h 20m
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FlixBus8h 45m004:05KarlsruheCentral Station12:50LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 18/12/2025 04:05:00 to Perrache Bus Stop, Lyon (France) arriving at 18/12/2025 12:50:00. 50 Economy ticket for £35 per person are available. Travel duration is 8h 45m
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FlixBus10h 10m010:25KarlsruheCentral Station20:35LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 18/12/2025 10:25:00 to Perrache Bus Stop, Lyon (France) arriving at 18/12/2025 20:35:00. 50 Economy ticket for £33 per person are available. Travel duration is 10h 10m
Fastest Flights Thursday
Fastest Buses Thursday
Here you will find all operators and timetables for a
Bus from Karlsruhe to Lyon
What are the most popular stations in Karlsruhe and Lyon?
In Karlsruhe, you will usually depart from Central Station, Heidehof Train Station or Tullastraße / Verkehrsbetriebe Train Station, while in Lyon you will be arriving at Perrache Bus Stop, Part-Dieu Train Station or Perrache Train Station, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Lyon from Karlsruhe? With 6 connections between 2 Bus and Flight operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Karlsruhe and Lyon, you can pay as low as £17 with a Bus from BlaBlaCar Bus.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Wizz Air: you will get to Lyon in just 5h 45m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Karlsruhe and Lyon are FlixBus, Ryanair and BlaBlaCar Bus, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Karlsruhe and Lyon is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Ettlingen or to Caluire-et-Cuire, and look at flights from Karlsruhe/Baden-Baden Airport, and landing at Lyons St. Exupery Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Karlsruhe to Lyon?
The most popular companies between Karlsruhe and Lyon, are FlixBus, Ryanair and BlaBlaCar Bus. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: FlixBus and BlaBlaCar Bus
Airlines: Ryanair, Skyscanner, LC Perú and 1 more.
All you need to know when you travel from Karlsruhe to Lyon
Check all information on comfort and services on all modes of transports from Karlsruhe to Lyon. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Karlsruhe to Lyon
How can I reach Lyon from Karlsruhe?
Every day, there are on average 6 connections between Bus and Flight, with which you can get to Lyon from Karlsruhe.
How far is Lyon from Karlsruhe?
The distance between Karlsruhe and Lyon is 450.1 km.
What is the most ecofriendly mode of transport between Karlsruhe and Lyon?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 12 kgs of CO2, a train 16 kgs, a car 77 kgs, and a flight 111 kgs.
What is the cheapest mode of transport from Karlsruhe to Lyon?
You can get to Lyon with just £17 by taking a Bus from BlaBlaCar Bus.
What is the fastest way to get from Karlsruhe to Lyon?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Lyon in just 5h 45m with a Flight from Wizz Air.
More routes to Karlsruhe and to Lyon
Looking for more options? Here you can see the most popular routes to Karlsruhe and to Lyon. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Karlsruhe
- Berlin to Karlsruhe
- Bremen to Karlsruhe
- Dortmund to Karlsruhe
- Dresden to Karlsruhe
- Dusseldorf to Karlsruhe
- Frankfurt am Main Airport to Karlsruhe
- Frankfurt am Main to Karlsruhe
- Frankfurt Hahn Airport to Karlsruhe
- Freiburg to Karlsruhe
- Hamburg to Karlsruhe
- Innsbruck to Karlsruhe
- Lille to Karlsruhe
- Mannheim to Karlsruhe
- Memmingen Airport to Karlsruhe
- Milan to Karlsruhe
- Munich to Karlsruhe
- Nuremberg to Karlsruhe
- Paris to Karlsruhe
- Saarbruecken to Karlsruhe
- Strasbourg to Karlsruhe
- Stuttgart Airport to Karlsruhe
- Stuttgart to Karlsruhe
- Vienna to Karlsruhe
- Trips to Lyon
- Alicante to Lyon
- Barcelona to Lyon
- Bordeaux to Lyon
- Caen to Lyon
- Castellón de la Plana to Lyon
- Chambery to Lyon
- Dijon to Lyon
- Dusseldorf to Lyon
- Geneva to Lyon
- Genoa to Lyon
- Grenoble to Lyon
- Lisbon to Lyon
- London to Lyon
- Lyons St. Exupery Airport to Lyon
- Marseille to Lyon
- Nantes to Lyon
- Nice to Lyon
- Paris to Lyon
- Poitiers to Lyon
- Rome to Lyon
- Sallanches to Lyon
- Toulouse to Lyon
- Turin to Lyon
- Valencia to Lyon

