What is the best way to travel from Lyon to Frankfurt am Main?
Looking for a trip? Check and compare all the available Trains, Flights and Buses to Frankfurt am Main from Lyon. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 3 available companies to find your perfect trip!
What is the cheapest way to reach Frankfurt am Main from Lyon?
You can reach Frankfurt am Main with just £28 by taking a Bus from FlixBus, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
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BlaBlaCar Bus10h 50m003:20LyonPerrache Train Station14:10Frankfurt am MainCentral Coach Station0EconomyA Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 21/03/2026 03:20:00 to Central Coach Station, Frankfurt am Main (Germany) arriving at 21/03/2026 14:10:00. 50 Economy ticket for £33 per person are available. Travel duration is 10h 50m
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BlaBlaCar Bus11h 15m002:05LyonPerrache Train Station13:20Frankfurt am MainCentral Coach Station0EconomyA Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 21/03/2026 02:05:00 to Central Coach Station, Frankfurt am Main (Germany) arriving at 21/03/2026 13:20:00. 50 Economy ticket for £35 per person are available. Travel duration is 11h 15m
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FlixBus13h 45m018:15LyonLyon Avenue Tony Garnier Coach Stop08:00Frankfurt am MainCentral Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 21/03/2026 18:15:00 to Central Station, Frankfurt am Main (Germany) arriving at 22/03/2026 08:00:00. 50 Economy ticket for £36 per person are available. Travel duration is 13h 45m
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FlixBus12h 45m017:05LyonLyon Avenue Tony Garnier Coach Stop05:50Frankfurt am MainCentral Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 21/03/2026 17:05:00 to Central Station, Frankfurt am Main (Germany) arriving at 22/03/2026 05:50:00. 50 Economy ticket for £37 per person are available. Travel duration is 12h 45m
Cheapest Buses Saturday
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FlixBus10h 0m002:25LyonLyon Avenue Tony Garnier Coach Stop12:25Frankfurt am MainCentral Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 22/03/2026 02:25:00 to Central Station, Frankfurt am Main (Germany) arriving at 22/03/2026 12:25:00. 50 Economy ticket for £40 per person are available. Travel duration is 10h 0m
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FlixBus12h 45m007:30LyonLyon Avenue Tony Garnier Coach Stop20:15Frankfurt am MainCentral Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 22/03/2026 07:30:00 to Central Station, Frankfurt am Main (Germany) arriving at 22/03/2026 20:15:00. 50 Economy ticket for £43 per person are available. Travel duration is 12h 45m
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FlixBus12h 45m017:05LyonLyon Avenue Tony Garnier Coach Stop05:50Frankfurt am MainCentral Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 22/03/2026 17:05:00 to Central Station, Frankfurt am Main (Germany) arriving at 23/03/2026 05:50:00. 50 Economy ticket for £47 per person are available. Travel duration is 12h 45m
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FlixBus11h 45m023:00LyonLyon Avenue Tony Garnier Coach Stop10:45Frankfurt am MainCentral Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 22/03/2026 23:00:00 to Central Station, Frankfurt am Main (Germany) arriving at 23/03/2026 10:45:00. 50 Economy ticket for £51 per person are available. Travel duration is 11h 45m
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TGV Lyria6h 44m009:16LyonPart-Dieu Train Station16:00Frankfurt am MainCentral Station0EconomyA Train from TGV Lyria goes from Part-Dieu Train Station, Lyon (France) at 22/03/2026 09:16:00 to Central Station, Frankfurt am Main (Germany) arriving at 22/03/2026 16:00:00. 50 Economy ticket for £98 per person are available. Travel duration is 6h 44m
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TGV Lyria7h 13m012:00LyonPart-Dieu Train Station19:13Frankfurt am MainCentral Station0EconomyA Train from TGV Lyria goes from Part-Dieu Train Station, Lyon (France) at 22/03/2026 12:00:00 to Central Station, Frankfurt am Main (Germany) arriving at 22/03/2026 19:13:00. 50 Economy ticket for £166 per person are available. Travel duration is 7h 13m
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TGV Lyria6h 52m008:04LyonPart-Dieu Train Station14:56Frankfurt am MainCentral Station0EconomyA Train from TGV Lyria goes from Part-Dieu Train Station, Lyon (France) at 22/03/2026 08:04:00 to Central Station, Frankfurt am Main (Germany) arriving at 22/03/2026 14:56:00. 50 Economy ticket for £180 per person are available. Travel duration is 6h 52m
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TGV Lyria6h 59m010:04LyonPart-Dieu Train Station17:03Frankfurt am MainCentral Station0EconomyA Train from TGV Lyria goes from Part-Dieu Train Station, Lyon (France) at 22/03/2026 10:04:00 to Central Station, Frankfurt am Main (Germany) arriving at 22/03/2026 17:03:00. 50 Economy ticket for £208 per person are available. Travel duration is 6h 59m
Cheapest Buses Sunday
Cheapest Trains Sunday
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FlixBus12h 5m018:15LyonLyon Avenue Tony Garnier Coach Stop06:20Frankfurt am MainCentral Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 23/03/2026 18:15:00 to Central Station, Frankfurt am Main (Germany) arriving at 24/03/2026 06:20:00. 50 Economy ticket for £29 per person are available. Travel duration is 12h 5m
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FlixBus12h 45m007:30LyonLyon Avenue Tony Garnier Coach Stop20:15Frankfurt am MainCentral Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 23/03/2026 07:30:00 to Central Station, Frankfurt am Main (Germany) arriving at 23/03/2026 20:15:00. 50 Economy ticket for £31 per person are available. Travel duration is 12h 45m
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FlixBus11h 45m023:00LyonLyon Avenue Tony Garnier Coach Stop10:45Frankfurt am MainCentral Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 23/03/2026 23:00:00 to Central Station, Frankfurt am Main (Germany) arriving at 24/03/2026 10:45:00. 50 Economy ticket for £32 per person are available. Travel duration is 11h 45m
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FlixBus10h 0m002:25LyonLyon Avenue Tony Garnier Coach Stop12:25Frankfurt am MainCentral Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 23/03/2026 02:25:00 to Central Station, Frankfurt am Main (Germany) arriving at 23/03/2026 12:25:00. 50 Economy ticket for £49 per person are available. Travel duration is 10h 0m
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TGV Lyria7h 35m011:38LyonPart-Dieu Train Station19:13Frankfurt am MainCentral Station0EconomyA Train from TGV Lyria goes from Part-Dieu Train Station, Lyon (France) at 23/03/2026 11:38:00 to Central Station, Frankfurt am Main (Germany) arriving at 23/03/2026 19:13:00. 50 Economy ticket for £93 per person are available. Travel duration is 7h 35m
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TGV Lyria5h 59m010:01LyonPart-Dieu Train Station16:00Frankfurt am MainCentral Station0EconomyA Train from TGV Lyria goes from Part-Dieu Train Station, Lyon (France) at 23/03/2026 10:01:00 to Central Station, Frankfurt am Main (Germany) arriving at 23/03/2026 16:00:00. 50 Economy ticket for £94 per person are available. Travel duration is 5h 59m
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TGV Lyria6h 59m016:04LyonPart-Dieu Train Station23:03Frankfurt am MainCentral Station0EconomyA Train from TGV Lyria goes from Part-Dieu Train Station, Lyon (France) at 23/03/2026 16:04:00 to Central Station, Frankfurt am Main (Germany) arriving at 23/03/2026 23:03:00. 50 Economy ticket for £126 per person are available. Travel duration is 6h 59m
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TGV Lyria6h 59m014:04LyonPart-Dieu Train Station21:03Frankfurt am MainCentral Station0EconomyA Train from TGV Lyria goes from Part-Dieu Train Station, Lyon (France) at 23/03/2026 14:04:00 to Central Station, Frankfurt am Main (Germany) arriving at 23/03/2026 21:03:00. 50 Economy ticket for £127 per person are available. Travel duration is 6h 59m
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Volotea10h 40m007:15Lyons St. Exupery AirportAéroport St Exupéry Coach Station17:55Frankfurt am Main AirportFrankfurt am Main Airport0EconomyA Flight from Volotea goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 23/03/2026 07:15:00 to Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) arriving at 23/03/2026 17:55:00. 50 Economy ticket for £97 per person are available. Travel duration is 10h 40m
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Air France14h 25m018:30Lyons St. Exupery AirportAéroport St Exupéry Coach Station08:55Frankfurt am Main AirportFrankfurt am Main Airport0EconomyA Flight from Air France goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 23/03/2026 18:30:00 to Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) arriving at 24/03/2026 08:55:00. 50 Economy ticket for £114 per person are available. Travel duration is 14h 25m
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Ryanair9h 25m008:25Lyons St. Exupery AirportLyons St. Exupery Airport17:50Frankfurt am Main AirportFrankfurt am Main Airport0EconomyA Flight from Ryanair goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 23/03/2026 08:25:00 to Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) arriving at 23/03/2026 17:50:00. 50 Economy ticket for £131 per person are available. Travel duration is 9h 25m
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EasyJet Airline20h 0m012:40Lyons St. Exupery AirportAéroport St Exupéry Coach Station08:40Frankfurt am Main AirportFrankfurt am Main Airport0EconomyA Flight from EasyJet Airline goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 23/03/2026 12:40:00 to Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) arriving at 24/03/2026 08:40:00. 50 Economy ticket for £149 per person are available. Travel duration is 20h 0m
Cheapest Buses Monday
Cheapest Trains Monday
Cheapest Flights Monday
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FlixBus10h 0m002:25LyonLyon Avenue Tony Garnier Coach Stop12:25Frankfurt am MainCentral Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 24/03/2026 02:25:00 to Central Station, Frankfurt am Main (Germany) arriving at 24/03/2026 12:25:00. 50 Economy ticket for £28 per person are available. Travel duration is 10h 0m
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FlixBus11h 45m023:00LyonLyon Avenue Tony Garnier Coach Stop10:45Frankfurt am MainCentral Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 24/03/2026 23:00:00 to Central Station, Frankfurt am Main (Germany) arriving at 25/03/2026 10:45:00. 50 Economy ticket for £31 per person are available. Travel duration is 11h 45m
Cheapest Buses Tuesday
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FlixBus10h 0m002:25LyonLyon Avenue Tony Garnier Coach Stop12:25Frankfurt am MainCentral Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 26/03/2026 02:25:00 to Central Station, Frankfurt am Main (Germany) arriving at 26/03/2026 12:25:00. 50 Economy ticket for £28 per person are available. Travel duration is 10h 0m
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FlixBus12h 45m007:30LyonLyon Avenue Tony Garnier Coach Stop20:15Frankfurt am MainCentral Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 26/03/2026 07:30:00 to Central Station, Frankfurt am Main (Germany) arriving at 26/03/2026 20:15:00. 50 Economy ticket for £34 per person are available. Travel duration is 12h 45m
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FlixBus12h 5m018:15LyonLyon Avenue Tony Garnier Coach Stop06:20Frankfurt am MainCentral Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 26/03/2026 18:15:00 to Central Station, Frankfurt am Main (Germany) arriving at 27/03/2026 06:20:00. 50 Economy ticket for £45 per person are available. Travel duration is 12h 5m
Cheapest Buses Thursday
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FlixBus10h 0m002:25LyonLyon Avenue Tony Garnier Coach Stop12:25Frankfurt am MainCentral Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 27/03/2026 02:25:00 to Central Station, Frankfurt am Main (Germany) arriving at 27/03/2026 12:25:00. 50 Economy ticket for £32 per person are available. Travel duration is 10h 0m
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FlixBus12h 45m007:30LyonLyon Avenue Tony Garnier Coach Stop20:15Frankfurt am MainCentral Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 27/03/2026 07:30:00 to Central Station, Frankfurt am Main (Germany) arriving at 27/03/2026 20:15:00. 50 Economy ticket for £36 per person are available. Travel duration is 12h 45m
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FlixBus12h 45m017:05LyonLyon Avenue Tony Garnier Coach Stop05:50Frankfurt am MainCentral Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 27/03/2026 17:05:00 to Central Station, Frankfurt am Main (Germany) arriving at 28/03/2026 05:50:00. 50 Economy ticket for £36 per person are available. Travel duration is 12h 45m
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FlixBus13h 45m018:15LyonLyon Avenue Tony Garnier Coach Stop08:00Frankfurt am MainCentral Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 27/03/2026 18:15:00 to Central Station, Frankfurt am Main (Germany) arriving at 28/03/2026 08:00:00. 50 Economy ticket for £36 per person are available. Travel duration is 13h 45m
Cheapest Buses Friday
What are the fastest trips from Lyon to Frankfurt am Main?
You can get to Frankfurt am Main from Lyon in just 4h 30m with a Flight from KLM - Royal Dutch Airlines. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
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FlixBus10h 0m002:25LyonLyon Avenue Tony Garnier Coach Stop12:25Frankfurt am MainCentral Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 21/03/2026 02:25:00 to Central Station, Frankfurt am Main (Germany) arriving at 21/03/2026 12:25:00. 50 Economy ticket for £43 per person are available. Travel duration is 10h 0m
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BlaBlaCar Bus10h 50m003:20LyonPerrache Train Station14:10Frankfurt am MainCentral Coach Station0EconomyA Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 21/03/2026 03:20:00 to Central Coach Station, Frankfurt am Main (Germany) arriving at 21/03/2026 14:10:00. 50 Economy ticket for £33 per person are available. Travel duration is 10h 50m
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BlaBlaCar Bus11h 15m002:05LyonPerrache Train Station13:20Frankfurt am MainCentral Coach Station0EconomyA Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 21/03/2026 02:05:00 to Central Coach Station, Frankfurt am Main (Germany) arriving at 21/03/2026 13:20:00. 50 Economy ticket for £35 per person are available. Travel duration is 11h 15m
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FlixBus12h 45m017:05LyonLyon Avenue Tony Garnier Coach Stop05:50Frankfurt am MainCentral Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 21/03/2026 17:05:00 to Central Station, Frankfurt am Main (Germany) arriving at 22/03/2026 05:50:00. 50 Economy ticket for £37 per person are available. Travel duration is 12h 45m
Fastest Buses Saturday
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TGV Lyria6h 44m009:16LyonPart-Dieu Train Station16:00Frankfurt am MainCentral Station0EconomyA Train from TGV Lyria goes from Part-Dieu Train Station, Lyon (France) at 22/03/2026 09:16:00 to Central Station, Frankfurt am Main (Germany) arriving at 22/03/2026 16:00:00. 50 Economy ticket for £98 per person are available. Travel duration is 6h 44m
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TGV Lyria6h 52m008:04LyonPart-Dieu Train Station14:56Frankfurt am MainCentral Station0EconomyA Train from TGV Lyria goes from Part-Dieu Train Station, Lyon (France) at 22/03/2026 08:04:00 to Central Station, Frankfurt am Main (Germany) arriving at 22/03/2026 14:56:00. 50 Economy ticket for £180 per person are available. Travel duration is 6h 52m
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TGV Lyria6h 59m010:04LyonPart-Dieu Train Station17:03Frankfurt am MainCentral Station0EconomyA Train from TGV Lyria goes from Part-Dieu Train Station, Lyon (France) at 22/03/2026 10:04:00 to Central Station, Frankfurt am Main (Germany) arriving at 22/03/2026 17:03:00. 50 Economy ticket for £208 per person are available. Travel duration is 6h 59m
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TGV Lyria6h 59m016:04LyonPart-Dieu Train Station23:03Frankfurt am MainCentral Station0EconomyA Train from TGV Lyria goes from Part-Dieu Train Station, Lyon (France) at 22/03/2026 16:04:00 to Central Station, Frankfurt am Main (Germany) arriving at 22/03/2026 23:03:00. 50 Economy ticket for £209 per person are available. Travel duration is 6h 59m
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FlixBus10h 0m002:25LyonLyon Avenue Tony Garnier Coach Stop12:25Frankfurt am MainCentral Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 22/03/2026 02:25:00 to Central Station, Frankfurt am Main (Germany) arriving at 22/03/2026 12:25:00. 50 Economy ticket for £40 per person are available. Travel duration is 10h 0m
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FlixBus11h 45m023:00LyonLyon Avenue Tony Garnier Coach Stop10:45Frankfurt am MainCentral Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 22/03/2026 23:00:00 to Central Station, Frankfurt am Main (Germany) arriving at 23/03/2026 10:45:00. 50 Economy ticket for £51 per person are available. Travel duration is 11h 45m
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FlixBus12h 45m007:30LyonLyon Avenue Tony Garnier Coach Stop20:15Frankfurt am MainCentral Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 22/03/2026 07:30:00 to Central Station, Frankfurt am Main (Germany) arriving at 22/03/2026 20:15:00. 50 Economy ticket for £43 per person are available. Travel duration is 12h 45m
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FlixBus12h 45m017:05LyonLyon Avenue Tony Garnier Coach Stop05:50Frankfurt am MainCentral Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 22/03/2026 17:05:00 to Central Station, Frankfurt am Main (Germany) arriving at 23/03/2026 05:50:00. 50 Economy ticket for £47 per person are available. Travel duration is 12h 45m
Fastest Trains Sunday
Fastest Buses Sunday
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KLM - Royal Dutch Airlines4h 30m014:10Lyons St. Exupery AirportAéroport St Exupéry Coach Station18:40Frankfurt am Main AirportFrankfurt am Main Airport0EconomyA Flight from KLM - Royal Dutch Airlines goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 23/03/2026 14:10:00 to Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) arriving at 23/03/2026 18:40:00. 50 Economy ticket for £160 per person are available. Travel duration is 4h 30m
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Ryanair9h 25m008:25Lyons St. Exupery AirportLyons St. Exupery Airport17:50Frankfurt am Main AirportFrankfurt am Main Airport0EconomyA Flight from Ryanair goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 23/03/2026 08:25:00 to Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) arriving at 23/03/2026 17:50:00. 50 Economy ticket for £131 per person are available. Travel duration is 9h 25m
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Volotea10h 40m007:15Lyons St. Exupery AirportAéroport St Exupéry Coach Station17:55Frankfurt am Main AirportFrankfurt am Main Airport0EconomyA Flight from Volotea goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 23/03/2026 07:15:00 to Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) arriving at 23/03/2026 17:55:00. 50 Economy ticket for £97 per person are available. Travel duration is 10h 40m
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Air France14h 25m018:30Lyons St. Exupery AirportAéroport St Exupéry Coach Station08:55Frankfurt am Main AirportFrankfurt am Main Airport0EconomyA Flight from Air France goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 23/03/2026 18:30:00 to Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) arriving at 24/03/2026 08:55:00. 50 Economy ticket for £114 per person are available. Travel duration is 14h 25m
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TGV Lyria5h 59m010:01LyonPart-Dieu Train Station16:00Frankfurt am MainCentral Station0EconomyA Train from TGV Lyria goes from Part-Dieu Train Station, Lyon (France) at 23/03/2026 10:01:00 to Central Station, Frankfurt am Main (Germany) arriving at 23/03/2026 16:00:00. 50 Economy ticket for £94 per person are available. Travel duration is 5h 59m
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TGV Lyria6h 59m016:04LyonPart-Dieu Train Station23:03Frankfurt am MainCentral Station0EconomyA Train from TGV Lyria goes from Part-Dieu Train Station, Lyon (France) at 23/03/2026 16:04:00 to Central Station, Frankfurt am Main (Germany) arriving at 23/03/2026 23:03:00. 50 Economy ticket for £126 per person are available. Travel duration is 6h 59m
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TGV Lyria6h 59m014:04LyonPart-Dieu Train Station21:03Frankfurt am MainCentral Station0EconomyA Train from TGV Lyria goes from Part-Dieu Train Station, Lyon (France) at 23/03/2026 14:04:00 to Central Station, Frankfurt am Main (Germany) arriving at 23/03/2026 21:03:00. 50 Economy ticket for £127 per person are available. Travel duration is 6h 59m
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TGV Lyria6h 59m010:04LyonPart-Dieu Train Station17:03Frankfurt am MainCentral Station0EconomyA Train from TGV Lyria goes from Part-Dieu Train Station, Lyon (France) at 23/03/2026 10:04:00 to Central Station, Frankfurt am Main (Germany) arriving at 23/03/2026 17:03:00. 50 Economy ticket for £152 per person are available. Travel duration is 6h 59m
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FlixBus10h 0m002:25LyonLyon Avenue Tony Garnier Coach Stop12:25Frankfurt am MainCentral Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 23/03/2026 02:25:00 to Central Station, Frankfurt am Main (Germany) arriving at 23/03/2026 12:25:00. 50 Economy ticket for £49 per person are available. Travel duration is 10h 0m
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FlixBus11h 45m023:00LyonLyon Avenue Tony Garnier Coach Stop10:45Frankfurt am MainCentral Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 23/03/2026 23:00:00 to Central Station, Frankfurt am Main (Germany) arriving at 24/03/2026 10:45:00. 50 Economy ticket for £32 per person are available. Travel duration is 11h 45m
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FlixBus12h 5m018:15LyonLyon Avenue Tony Garnier Coach Stop06:20Frankfurt am MainCentral Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 23/03/2026 18:15:00 to Central Station, Frankfurt am Main (Germany) arriving at 24/03/2026 06:20:00. 50 Economy ticket for £29 per person are available. Travel duration is 12h 5m
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FlixBus12h 45m007:30LyonLyon Avenue Tony Garnier Coach Stop20:15Frankfurt am MainCentral Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 23/03/2026 07:30:00 to Central Station, Frankfurt am Main (Germany) arriving at 23/03/2026 20:15:00. 50 Economy ticket for £31 per person are available. Travel duration is 12h 45m
Fastest Flights Monday
Fastest Trains Monday
Fastest Buses Monday
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FlixBus10h 0m002:25LyonLyon Avenue Tony Garnier Coach Stop12:25Frankfurt am MainCentral Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 24/03/2026 02:25:00 to Central Station, Frankfurt am Main (Germany) arriving at 24/03/2026 12:25:00. 50 Economy ticket for £28 per person are available. Travel duration is 10h 0m
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FlixBus11h 45m023:00LyonLyon Avenue Tony Garnier Coach Stop10:45Frankfurt am MainCentral Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 24/03/2026 23:00:00 to Central Station, Frankfurt am Main (Germany) arriving at 25/03/2026 10:45:00. 50 Economy ticket for £31 per person are available. Travel duration is 11h 45m
Fastest Buses Tuesday
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FlixBus10h 0m002:25LyonLyon Avenue Tony Garnier Coach Stop12:25Frankfurt am MainCentral Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 26/03/2026 02:25:00 to Central Station, Frankfurt am Main (Germany) arriving at 26/03/2026 12:25:00. 50 Economy ticket for £28 per person are available. Travel duration is 10h 0m
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FlixBus12h 5m018:15LyonLyon Avenue Tony Garnier Coach Stop06:20Frankfurt am MainCentral Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 26/03/2026 18:15:00 to Central Station, Frankfurt am Main (Germany) arriving at 27/03/2026 06:20:00. 50 Economy ticket for £45 per person are available. Travel duration is 12h 5m
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FlixBus12h 45m007:30LyonLyon Avenue Tony Garnier Coach Stop20:15Frankfurt am MainCentral Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 26/03/2026 07:30:00 to Central Station, Frankfurt am Main (Germany) arriving at 26/03/2026 20:15:00. 50 Economy ticket for £34 per person are available. Travel duration is 12h 45m
Fastest Buses Thursday
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FlixBus10h 0m002:25LyonLyon Avenue Tony Garnier Coach Stop12:25Frankfurt am MainCentral Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 27/03/2026 02:25:00 to Central Station, Frankfurt am Main (Germany) arriving at 27/03/2026 12:25:00. 50 Economy ticket for £32 per person are available. Travel duration is 10h 0m
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FlixBus11h 45m023:00LyonLyon Avenue Tony Garnier Coach Stop10:45Frankfurt am MainCentral Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 27/03/2026 23:00:00 to Central Station, Frankfurt am Main (Germany) arriving at 28/03/2026 10:45:00. 50 Economy ticket for £39 per person are available. Travel duration is 11h 45m
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FlixBus12h 45m007:30LyonLyon Avenue Tony Garnier Coach Stop20:15Frankfurt am MainCentral Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 27/03/2026 07:30:00 to Central Station, Frankfurt am Main (Germany) arriving at 27/03/2026 20:15:00. 50 Economy ticket for £36 per person are available. Travel duration is 12h 45m
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FlixBus12h 45m017:05LyonLyon Avenue Tony Garnier Coach Stop05:50Frankfurt am MainCentral Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 27/03/2026 17:05:00 to Central Station, Frankfurt am Main (Germany) arriving at 28/03/2026 05:50:00. 50 Economy ticket for £36 per person are available. Travel duration is 12h 45m
Fastest Buses Friday
Here you will find all operators and timetables for a
Bus from Lyon to Frankfurt am Main
What are the most popular stations in Lyon and Frankfurt am Main?
In Lyon, you will usually depart from Perrache Bus Stop, Part-Dieu Train Station or Perrache Train Station, while in Frankfurt am Main you will be arriving at Central Station, Central Coach Station or West Train Station, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Frankfurt am Main from Lyon? With 6 connections between 3 Flight, Train and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Lyon and Frankfurt am Main, you can pay as low as £28 with a Bus from FlixBus.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from KLM - Royal Dutch Airlines: you will get to Frankfurt am Main in just 4h 30m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Lyon and Frankfurt am Main are FlixBus, TGV Lyria and BlaBlaCar Bus, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Lyon and Frankfurt am Main is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Caluire-et-Cuire or to Neu-Isenburg, and look at flights from Lyons St. Exupery Airport, and landing at Frankfurt am Main Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Lyon to Frankfurt am Main?
The most popular companies between Lyon and Frankfurt am Main, are FlixBus, TGV Lyria and BlaBlaCar Bus. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: FlixBus and BlaBlaCar Bus
Train companies: TGV Lyria
Airlines: Volotea, Air France, Ryanair and 2 more.
All you need to know when you travel from Lyon to Frankfurt am Main
Check all information on comfort and services on all modes of transports from Lyon to Frankfurt am Main. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Lyon to Frankfurt am Main
How can I reach Frankfurt am Main from Lyon?
Every day, there are on average 6 connections between Flight, Train and Bus, with which you can get to Frankfurt am Main from Lyon.
How far is Frankfurt am Main from Lyon?
The distance between Lyon and Frankfurt am Main is 562.3 km.
What is the most ecofriendly mode of transport between Lyon and Frankfurt am Main?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 15 kgs of CO2, a train 20 kgs, a car 96 kgs, and a flight 138 kgs.
What is the cheapest mode of transport from Lyon to Frankfurt am Main?
You can get to Frankfurt am Main with just £28 by taking a Bus from FlixBus.
What is the fastest way to get from Lyon to Frankfurt am Main?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Frankfurt am Main in just 4h 30m with a Flight from KLM - Royal Dutch Airlines.
More routes to Lyon and to Frankfurt am Main
Looking for more options? Here you can see the most popular routes to Lyon and to Frankfurt am Main. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Lyon
- Alicante to Lyon
- Annecy to Lyon
- Barcelona to Lyon
- Basel to Lyon
- Béziers to Lyon
- Bologna to Lyon
- Bordeaux to Lyon
- Chambery to Lyon
- Dijon to Lyon
- Dusseldorf to Lyon
- Geneva to Lyon
- Genoa to Lyon
- Grenoble to Lyon
- London to Lyon
- Marseille to Lyon
- Milan to Lyon
- Nancy to Lyon
- Nice to Lyon
- Paris to Lyon
- Rome to Lyon
- Strasbourg to Lyon
- Toulouse to Lyon
- Turin to Lyon
- Valencia to Lyon
- Trips to Frankfurt am Main
- Amsterdam to Frankfurt am Main
- Berlin to Frankfurt am Main
- Bonn to Frankfurt am Main
- Bremen to Frankfurt am Main
- Cologne to Frankfurt am Main
- Dresden to Frankfurt am Main
- Frankfurt Hahn Airport to Frankfurt am Main
- Freiburg to Frankfurt am Main
- Graz to Frankfurt am Main
- Hamburg Airport to Frankfurt am Main
- Hamburg to Frankfurt am Main
- Hanover Airport to Frankfurt am Main
- Hanover to Frankfurt am Main
- Leipzig to Frankfurt am Main
- London to Frankfurt am Main
- Marburg (Lahn) to Frankfurt am Main
- Munich to Frankfurt am Main
- Paris to Frankfurt am Main
- Rotterdam to Frankfurt am Main
- Sofia to Frankfurt am Main
- Strasbourg to Frankfurt am Main
- Vienna to Frankfurt am Main
- Zurich Airport to Frankfurt am Main
- Zurich to Frankfurt am Main
