Compare all timetables for the bus from Siena to Rome
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 2h 50m | 09:25 | Siena | Train Station | 12:15 | Rome | Tiburtina Bus Station | Premium Economy | £7 |
A Bus from Itabus goes from Train Station, Siena (Italy) at 18/06/2026 09:25:00 to Tiburtina Bus Station, Rome (Italy) arriving at 18/06/2026 12:15:00. 50 Premium Economy ticket for £7 per person are available. Travel duration is 2h 50m
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| Itabus | 2h 50m | 17:55 | Siena | Train Station | 20:45 | Rome | Tiburtina Bus Station | Premium Economy | £7 |
A Bus from Itabus goes from Train Station, Siena (Italy) at 18/06/2026 17:55:00 to Tiburtina Bus Station, Rome (Italy) arriving at 18/06/2026 20:45:00. 50 Premium Economy ticket for £7 per person are available. Travel duration is 2h 50m
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| FlixBus | 2h 50m | 19:45 | Siena | Train Station | 22:35 | Rome | Tiburtina Bus Station | Economy | £7 |
A Bus from FlixBus goes from Train Station, Siena (Italy) at 18/06/2026 19:45:00 to Tiburtina Bus Station, Rome (Italy) arriving at 18/06/2026 22:35:00. 50 Economy ticket for £7 per person are available. Travel duration is 2h 50m
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| FlixBus | 2h 45m | 22:25 | Siena | Train Station | 01:10 | Rome | Tiburtina Bus Station | Economy | £7 |
A Bus from FlixBus goes from Train Station, Siena (Italy) at 18/06/2026 22:25:00 to Tiburtina Bus Station, Rome (Italy) arriving at 19/06/2026 01:10:00. 50 Economy ticket for £7 per person are available. Travel duration is 2h 45m
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| Busitalia Rail Service | 3h 0m | 20:30 | Siena | Piazza Antonio Gramsci | 23:30 | Rome | Tiburtina Bus Station | Economy | £10 |
A Bus from Busitalia Rail Service goes from Piazza Antonio Gramsci, Siena (Italy) at 18/06/2026 20:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 18/06/2026 23:30:00. 50 Economy ticket for £10 per person are available. Travel duration is 3h 0m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 2h 55m | 07:00 | Siena | Train Station | 09:55 | Rome | Tiburtina Bus Station | Economy | £5 |
A Bus from FlixBus goes from Train Station, Siena (Italy) at 19/06/2026 07:00:00 to Tiburtina Bus Station, Rome (Italy) arriving at 19/06/2026 09:55:00. 50 Economy ticket for £5 per person are available. Travel duration is 2h 55m
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| FlixBus | 2h 40m | 08:45 | Siena | Train Station | 11:25 | Rome | Tiburtina Bus Station | Economy | £5 |
A Bus from FlixBus goes from Train Station, Siena (Italy) at 19/06/2026 08:45:00 to Tiburtina Bus Station, Rome (Italy) arriving at 19/06/2026 11:25:00. 50 Economy ticket for £5 per person are available. Travel duration is 2h 40m
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| Itabus | 2h 50m | 09:25 | Siena | Central Bus Station | 12:15 | Rome | Tiburtina Coach Station | Economy | £8 |
A Bus from Itabus goes from Central Bus Station, Siena (Italy) at 19/06/2026 09:25:00 to Tiburtina Coach Station, Rome (Italy) arriving at 19/06/2026 12:15:00. 50 Economy ticket for £8 per person are available. Travel duration is 2h 50m
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| Itabus | 2h 50m | 05:15 | Siena | Central Bus Station | 08:05 | Rome | Tiburtina Coach Station | Economy | £11 |
A Bus from Itabus goes from Central Bus Station, Siena (Italy) at 19/06/2026 05:15:00 to Tiburtina Coach Station, Rome (Italy) arriving at 19/06/2026 08:05:00. 50 Economy ticket for £11 per person are available. Travel duration is 2h 50m
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| MarinoBus | 3h 10m | 20:30 | Siena | Train Station | 23:40 | Rome | Tiburtina Bus Station | Economy | £17 |
A Bus from MarinoBus goes from Train Station, Siena (Italy) at 19/06/2026 20:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 19/06/2026 23:40:00. 50 Economy ticket for £17 per person are available. Travel duration is 3h 10m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 2h 50m | 13:45 | Siena | Central Bus Station | 16:35 | Rome | Tiburtina Coach Station | Economy | £5 |
A Bus from Itabus goes from Central Bus Station, Siena (Italy) at 20/06/2026 13:45:00 to Tiburtina Coach Station, Rome (Italy) arriving at 20/06/2026 16:35:00. 50 Economy ticket for £5 per person are available. Travel duration is 2h 50m
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| Itabus | 2h 50m | 17:55 | Siena | Central Bus Station | 20:45 | Rome | Tiburtina Coach Station | Economy | £5 |
A Bus from Itabus goes from Central Bus Station, Siena (Italy) at 20/06/2026 17:55:00 to Tiburtina Coach Station, Rome (Italy) arriving at 20/06/2026 20:45:00. 50 Economy ticket for £5 per person are available. Travel duration is 2h 50m
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| Itabus | 2h 50m | 09:25 | Siena | Central Bus Station | 12:15 | Rome | Tiburtina Coach Station | Economy | £7 |
A Bus from Itabus goes from Central Bus Station, Siena (Italy) at 20/06/2026 09:25:00 to Tiburtina Coach Station, Rome (Italy) arriving at 20/06/2026 12:15:00. 50 Economy ticket for £7 per person are available. Travel duration is 2h 50m
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| MarinoBus | 3h 15m | 11:05 | Siena | Train Station | 14:20 | Rome | Tiburtina Bus Station | Economy | £16 |
A Bus from MarinoBus goes from Train Station, Siena (Italy) at 20/06/2026 11:05:00 to Tiburtina Bus Station, Rome (Italy) arriving at 20/06/2026 14:20:00. 50 Economy ticket for £16 per person are available. Travel duration is 3h 15m
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| MarinoBus | 3h 10m | 20:30 | Siena | Train Station | 23:40 | Rome | Tiburtina Bus Station | Economy | £20 |
A Bus from MarinoBus goes from Train Station, Siena (Italy) at 20/06/2026 20:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 20/06/2026 23:40:00. 50 Economy ticket for £20 per person are available. Travel duration is 3h 10m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 2h 50m | 09:25 | Siena | Central Bus Station | 12:15 | Rome | Tiburtina Coach Station | Economy | £7 |
A Bus from Itabus goes from Central Bus Station, Siena (Italy) at 21/06/2026 09:25:00 to Tiburtina Coach Station, Rome (Italy) arriving at 21/06/2026 12:15:00. 50 Economy ticket for £7 per person are available. Travel duration is 2h 50m
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| Itabus | 2h 50m | 13:45 | Siena | Central Bus Station | 16:35 | Rome | Tiburtina Coach Station | Economy | £7 |
A Bus from Itabus goes from Central Bus Station, Siena (Italy) at 21/06/2026 13:45:00 to Tiburtina Coach Station, Rome (Italy) arriving at 21/06/2026 16:35:00. 50 Economy ticket for £7 per person are available. Travel duration is 2h 50m
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| Itabus | 2h 50m | 17:55 | Siena | Central Bus Station | 20:45 | Rome | Tiburtina Coach Station | Economy | £7 |
A Bus from Itabus goes from Central Bus Station, Siena (Italy) at 21/06/2026 17:55:00 to Tiburtina Coach Station, Rome (Italy) arriving at 21/06/2026 20:45:00. 50 Economy ticket for £7 per person are available. Travel duration is 2h 50m
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| MarinoBus | 3h 15m | 11:05 | Siena | Train Station | 14:20 | Rome | Tiburtina Bus Station | Economy | £19 |
A Bus from MarinoBus goes from Train Station, Siena (Italy) at 21/06/2026 11:05:00 to Tiburtina Bus Station, Rome (Italy) arriving at 21/06/2026 14:20:00. 50 Economy ticket for £19 per person are available. Travel duration is 3h 15m
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| MarinoBus | 3h 10m | 20:30 | Siena | Train Station | 23:40 | Rome | Tiburtina Bus Station | Economy | £20 |
A Bus from MarinoBus goes from Train Station, Siena (Italy) at 21/06/2026 20:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 21/06/2026 23:40:00. 50 Economy ticket for £20 per person are available. Travel duration is 3h 10m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 2h 50m | 17:55 | Siena | Central Bus Station | 20:45 | Rome | Tiburtina Coach Station | Economy | £5 |
A Bus from Itabus goes from Central Bus Station, Siena (Italy) at 22/06/2026 17:55:00 to Tiburtina Coach Station, Rome (Italy) arriving at 22/06/2026 20:45:00. 50 Economy ticket for £5 per person are available. Travel duration is 2h 50m
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| Itabus | 2h 50m | 09:25 | Siena | Central Bus Station | 12:15 | Rome | Tiburtina Coach Station | Economy | £7 |
A Bus from Itabus goes from Central Bus Station, Siena (Italy) at 22/06/2026 09:25:00 to Tiburtina Coach Station, Rome (Italy) arriving at 22/06/2026 12:15:00. 50 Economy ticket for £7 per person are available. Travel duration is 2h 50m
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| Itabus | 2h 50m | 13:45 | Siena | Central Bus Station | 16:35 | Rome | Tiburtina Coach Station | Economy | £7 |
A Bus from Itabus goes from Central Bus Station, Siena (Italy) at 22/06/2026 13:45:00 to Tiburtina Coach Station, Rome (Italy) arriving at 22/06/2026 16:35:00. 50 Economy ticket for £7 per person are available. Travel duration is 2h 50m
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| MarinoBus | 3h 10m | 20:30 | Siena | Train Station | 23:40 | Rome | Tiburtina Bus Station | Economy | £17 |
A Bus from MarinoBus goes from Train Station, Siena (Italy) at 22/06/2026 20:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 22/06/2026 23:40:00. 50 Economy ticket for £17 per person are available. Travel duration is 3h 10m
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| MarinoBus | 3h 15m | 11:05 | Siena | Train Station | 14:20 | Rome | Tiburtina Bus Station | Economy | £18 |
A Bus from MarinoBus goes from Train Station, Siena (Italy) at 22/06/2026 11:05:00 to Tiburtina Bus Station, Rome (Italy) arriving at 22/06/2026 14:20:00. 50 Economy ticket for £18 per person are available. Travel duration is 3h 15m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 3h 5m | 05:35 | Siena | Train Station | 08:40 | Rome | Tiburtina Bus Station | Economy | £5 |
A Bus from FlixBus goes from Train Station, Siena (Italy) at 23/06/2026 05:35:00 to Tiburtina Bus Station, Rome (Italy) arriving at 23/06/2026 08:40:00. 50 Economy ticket for £5 per person are available. Travel duration is 3h 5m
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| FlixBus | 2h 55m | 07:00 | Siena | Train Station | 09:55 | Rome | Tiburtina Bus Station | Economy | £5 |
A Bus from FlixBus goes from Train Station, Siena (Italy) at 23/06/2026 07:00:00 to Tiburtina Bus Station, Rome (Italy) arriving at 23/06/2026 09:55:00. 50 Economy ticket for £5 per person are available. Travel duration is 2h 55m
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| Itabus | 2h 50m | 09:25 | Siena | Train Station | 12:15 | Rome | Tiburtina Bus Station | Premium Economy | £10 |
A Bus from Itabus goes from Train Station, Siena (Italy) at 23/06/2026 09:25:00 to Tiburtina Bus Station, Rome (Italy) arriving at 23/06/2026 12:15:00. 50 Premium Economy ticket for £10 per person are available. Travel duration is 2h 50m
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| Itabus | 2h 50m | 13:45 | Siena | Train Station | 16:35 | Rome | Tiburtina Bus Station | Premium Economy | £10 |
A Bus from Itabus goes from Train Station, Siena (Italy) at 23/06/2026 13:45:00 to Tiburtina Bus Station, Rome (Italy) arriving at 23/06/2026 16:35:00. 50 Premium Economy ticket for £10 per person are available. Travel duration is 2h 50m
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| MarinoBus | 3h 15m | 11:05 | Siena | Train Station | 14:20 | Rome | Tiburtina Bus Station | Economy | £16 |
A Bus from MarinoBus goes from Train Station, Siena (Italy) at 23/06/2026 11:05:00 to Tiburtina Bus Station, Rome (Italy) arriving at 23/06/2026 14:20:00. 50 Economy ticket for £16 per person are available. Travel duration is 3h 15m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 2h 55m | 07:00 | Siena | Train Station | 09:55 | Rome | Tiburtina Bus Station | Economy | £5 |
A Bus from FlixBus goes from Train Station, Siena (Italy) at 24/06/2026 07:00:00 to Tiburtina Bus Station, Rome (Italy) arriving at 24/06/2026 09:55:00. 50 Economy ticket for £5 per person are available. Travel duration is 2h 55m
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| FlixBus | 2h 50m | 10:45 | Siena | Train Station | 13:35 | Rome | Tiburtina Bus Station | Economy | £5 |
A Bus from FlixBus goes from Train Station, Siena (Italy) at 24/06/2026 10:45:00 to Tiburtina Bus Station, Rome (Italy) arriving at 24/06/2026 13:35:00. 50 Economy ticket for £5 per person are available. Travel duration is 2h 50m
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| Itabus | 2h 50m | 09:25 | Siena | Train Station | 12:15 | Rome | Tiburtina Bus Station | Premium Economy | £6 |
A Bus from Itabus goes from Train Station, Siena (Italy) at 24/06/2026 09:25:00 to Tiburtina Bus Station, Rome (Italy) arriving at 24/06/2026 12:15:00. 50 Premium Economy ticket for £6 per person are available. Travel duration is 2h 50m
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| Itabus | 2h 50m | 13:45 | Siena | Train Station | 16:35 | Rome | Tiburtina Bus Station | Premium Economy | £6 |
A Bus from Itabus goes from Train Station, Siena (Italy) at 24/06/2026 13:45:00 to Tiburtina Bus Station, Rome (Italy) arriving at 24/06/2026 16:35:00. 50 Premium Economy ticket for £6 per person are available. Travel duration is 2h 50m
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| MarinoBus | 3h 15m | 11:05 | Siena | Piazza Antonio Gramsci | 14:20 | Rome | Tiburtina Bus Station | Economy | £26 |
A Bus from MarinoBus goes from Piazza Antonio Gramsci, Siena (Italy) at 24/06/2026 11:05:00 to Tiburtina Bus Station, Rome (Italy) arriving at 24/06/2026 14:20:00. 50 Economy ticket for £26 per person are available. Travel duration is 3h 15m
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Best Price Offer: The price for the cheapest coach from Siena to Rome is £4 on 22/06/2026. Flexible travellers save on ticket prices.
Frequency of bus connections between Siena and Rome
Facts about coaches from Siena to Rome
Compare all providers like Itabus, MarinoBus and FlixBus that travel 34 times every day by bus from Siena to Rome in one click! Book your bus ticket from Siena to Rome starting from £4!
| Cheapest Bus | £4 |
| Fastest Bus | 2h 40m |
| Earliest Coach | 01:05 |
| Latest Coach | 20:30 |
| Daily Bus Connections | 34 Ø |
| Distance | 184.3 km |
| Coach Companies | Itabus, MarinoBus, FlixBus and Busitalia Rail Service |
Cheapest coach connections from Siena to Rome
Every day, 34 buses from 4 coach companies leave Siena for Rome: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 18/06/2026 and for the following days.
The cheapest time to travel from Siena to Rome
How to save money travelling from Siena to Rome
Book the ticket from Siena to Rome in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Siena to Rome, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Siena to Rome are also emptier.All bus stations and stops in Siena and Rome
The map below shows you where to find all the bus stations in Siena and Rome.
Compare the bus with other modes of transport
Service and Comfort on the bus from Siena to Rome
FAQs about the Siena to Rome bus
How much does a Siena - Rome coach trip cost?
How much could I save by comparing buses from Siena to Rome?
How many connections are available for the Siena - Rome route on average every day?
How long does a bus to Rome from Siena take?
What time is the first bus from Siena to Rome?
What time is the last coach from Siena to Rome?
Which bus companies serve the Siena - Rome route?
Is there a direct bus between Siena and Rome?
What can I take with me on the bus to Rome from Siena?
What equipment is available for the Siena Rome bus route?
How does CheckMyBus find the best bus deals from Siena to Rome?
How does CheckMyBus technology work for trips from Siena to Rome?
Available seat classes which are offered on the bus route Siena to Rome
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.
More bus routes to Siena and to Rome
- Bus Routes to Siena
- Coach Arezzo to Siena
- Bus from Bologna to Siena
- Bus to Siena from Cosenza
- Bus from Milan to Siena
- Buses Perugia to Siena
- Coach to Siena from Pescara
- Coach to Siena from Prato
- Bus Sala Consilina to Siena
- Bus to Siena from Salerno
- Coach from Taranto to Siena
- Bus from Turin to Siena
- Bus Routes to Rome
- Coach to Rome from Altamura
- Coaches Amalfi to Rome
- Buses Arezzo to Rome
- Coach Avezzano to Rome
- Coach from Benevento to Rome
- Bus from Calopezzati to Rome
- Coach to Rome from Castrovillari
- Buses Civitavecchia to Rome
- Bus to Rome from Crotone
- Coach to Rome from Florence
- Bus to Rome from Foggia
- London to Rome coach
- Pistoia to Rome bus
- Coach to Rome from Policoro
- Coach from San Severo to Rome
- Coach Sibari to Rome
- Coach to Rome from Udine
- Val Vomano to Rome coach
- Vasto to Rome bus
- Venice to Rome coach
