Bus and Coach from Siena to Rome: Compare all prices

Compare all timetables for the bus from Siena to Rome

Here is a selection of the cheapest bus trips from the schedule from Siena to Rome from various bus operators like Itabus, FlixBus or MarinoBus for the next days.

today

tomorrow

£4

Sunday

£6

Monday

£6

Tuesday

£9

Wednesday

£4

Thursday

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Itabus	2h 50m	13:45	Siena	Train Station	16:35	Rome	Tiburtina Bus Station	Premium Economy	£4	A Bus from Itabus goes from Train Station, Siena (Italy) at 21/03/2026 13:45:00 to Tiburtina Bus Station, Rome (Italy) arriving at 21/03/2026 16:35:00. 50 Premium Economy ticket for £4 per person are available. Travel duration is 2h 50m
Itabus	2h 50m	16:25	Siena	Train Station	19:15	Rome	Tiburtina Bus Station	Premium Economy	£4	A Bus from Itabus goes from Train Station, Siena (Italy) at 21/03/2026 16:25:00 to Tiburtina Bus Station, Rome (Italy) arriving at 21/03/2026 19:15:00. 50 Premium Economy ticket for £4 per person are available. Travel duration is 2h 50m
FlixBus	2h 40m	12:40	Siena	Train Station	15:20	Rome	Tiburtina Bus Station	Economy	£5	A Bus from FlixBus goes from Train Station, Siena (Italy) at 21/03/2026 12:40:00 to Tiburtina Bus Station, Rome (Italy) arriving at 21/03/2026 15:20:00. 50 Economy ticket for £5 per person are available. Travel duration is 2h 40m
FlixBus	2h 50m	15:45	Siena	Train Station	18:35	Rome	Tiburtina Bus Station	Economy	£5	A Bus from FlixBus goes from Train Station, Siena (Italy) at 21/03/2026 15:45:00 to Tiburtina Bus Station, Rome (Italy) arriving at 21/03/2026 18:35:00. 50 Economy ticket for £5 per person are available. Travel duration is 2h 50m
MarinoBus	3h 15m	11:05	Siena	Train Station	14:20	Rome	Tiburtina Bus Station	Basic	£11	A Bus from MarinoBus goes from Train Station, Siena (Italy) at 21/03/2026 11:05:00 to Tiburtina Bus Station, Rome (Italy) arriving at 21/03/2026 14:20:00. 50 Basic ticket for £11 per person are available. Travel duration is 3h 15m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Itabus	2h 50m	09:25	Siena	Train Station	12:15	Rome	Tiburtina Bus Station	Premium Economy	£6	A Bus from Itabus goes from Train Station, Siena (Italy) at 22/03/2026 09:25:00 to Tiburtina Bus Station, Rome (Italy) arriving at 22/03/2026 12:15:00. 50 Premium Economy ticket for £6 per person are available. Travel duration is 2h 50m
Itabus	2h 50m	12:10	Siena	Train Station	15:00	Rome	Tiburtina Bus Station	Premium Economy	£6	A Bus from Itabus goes from Train Station, Siena (Italy) at 22/03/2026 12:10:00 to Tiburtina Bus Station, Rome (Italy) arriving at 22/03/2026 15:00:00. 50 Premium Economy ticket for £6 per person are available. Travel duration is 2h 50m
FlixBus	2h 55m	07:00	Siena	Train Station	09:55	Rome	Tiburtina Bus Station	Economy	£7	A Bus from FlixBus goes from Train Station, Siena (Italy) at 22/03/2026 07:00:00 to Tiburtina Bus Station, Rome (Italy) arriving at 22/03/2026 09:55:00. 50 Economy ticket for £7 per person are available. Travel duration is 2h 55m
FlixBus	2h 40m	08:45	Siena	Train Station	11:25	Rome	Tiburtina Bus Station	Economy	£7	A Bus from FlixBus goes from Train Station, Siena (Italy) at 22/03/2026 08:45:00 to Tiburtina Bus Station, Rome (Italy) arriving at 22/03/2026 11:25:00. 50 Economy ticket for £7 per person are available. Travel duration is 2h 40m
MarinoBus	3h 15m	11:05	Siena	Train Station	14:20	Rome	Tiburtina Bus Station	Basic	£11	A Bus from MarinoBus goes from Train Station, Siena (Italy) at 22/03/2026 11:05:00 to Tiburtina Bus Station, Rome (Italy) arriving at 22/03/2026 14:20:00. 50 Basic ticket for £11 per person are available. Travel duration is 3h 15m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Itabus	2h 50m	09:25	Siena	Train Station	12:15	Rome	Tiburtina Bus Station	Premium Economy	£6	A Bus from Itabus goes from Train Station, Siena (Italy) at 23/03/2026 09:25:00 to Tiburtina Bus Station, Rome (Italy) arriving at 23/03/2026 12:15:00. 50 Premium Economy ticket for £6 per person are available. Travel duration is 2h 50m
Itabus	2h 50m	12:10	Siena	Train Station	15:00	Rome	Tiburtina Bus Station	Premium Economy	£6	A Bus from Itabus goes from Train Station, Siena (Italy) at 23/03/2026 12:10:00 to Tiburtina Bus Station, Rome (Italy) arriving at 23/03/2026 15:00:00. 50 Premium Economy ticket for £6 per person are available. Travel duration is 2h 50m
FlixBus	2h 50m	19:45	Siena	Train Station	22:35	Rome	Tiburtina Bus Station	Economy	£6	A Bus from FlixBus goes from Train Station, Siena (Italy) at 23/03/2026 19:45:00 to Tiburtina Bus Station, Rome (Italy) arriving at 23/03/2026 22:35:00. 50 Economy ticket for £6 per person are available. Travel duration is 2h 50m
FlixBus	2h 45m	21:00	Siena	Train Station	23:45	Rome	Tiburtina Bus Station	Economy	£6	A Bus from FlixBus goes from Train Station, Siena (Italy) at 23/03/2026 21:00:00 to Tiburtina Bus Station, Rome (Italy) arriving at 23/03/2026 23:45:00. 50 Economy ticket for £6 per person are available. Travel duration is 2h 45m
MarinoBus	3h 15m	11:05	Siena	Train Station	14:20	Rome	Tiburtina Bus Station	Basic	£11	A Bus from MarinoBus goes from Train Station, Siena (Italy) at 23/03/2026 11:05:00 to Tiburtina Bus Station, Rome (Italy) arriving at 23/03/2026 14:20:00. 50 Basic ticket for £11 per person are available. Travel duration is 3h 15m

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Itabus	2h 50m	13:45	Siena	Train Station	16:35	Rome	Tiburtina Bus Station	Premium Economy	£9	A Bus from Itabus goes from Train Station, Siena (Italy) at 24/03/2026 13:45:00 to Tiburtina Bus Station, Rome (Italy) arriving at 24/03/2026 16:35:00. 50 Premium Economy ticket for £9 per person are available. Travel duration is 2h 50m
Itabus	2h 50m	16:25	Siena	Train Station	19:15	Rome	Tiburtina Bus Station	Premium Economy	£9	A Bus from Itabus goes from Train Station, Siena (Italy) at 24/03/2026 16:25:00 to Tiburtina Bus Station, Rome (Italy) arriving at 24/03/2026 19:15:00. 50 Premium Economy ticket for £9 per person are available. Travel duration is 2h 50m
Itabus	2h 50m	17:55	Siena	Train Station	20:45	Rome	Tiburtina Bus Station	Premium Economy	£11	A Bus from Itabus goes from Train Station, Siena (Italy) at 24/03/2026 17:55:00 to Tiburtina Bus Station, Rome (Italy) arriving at 24/03/2026 20:45:00. 50 Premium Economy ticket for £11 per person are available. Travel duration is 2h 50m
MarinoBus	3h 15m	11:05	Siena	Train Station	14:20	Rome	Tiburtina Bus Station	Basic	£12	A Bus from MarinoBus goes from Train Station, Siena (Italy) at 24/03/2026 11:05:00 to Tiburtina Bus Station, Rome (Italy) arriving at 24/03/2026 14:20:00. 50 Basic ticket for £12 per person are available. Travel duration is 3h 15m
MarinoBus	3h 10m	20:30	Siena	Train Station	23:40	Rome	Tiburtina Bus Station	Basic	£21	A Bus from MarinoBus goes from Train Station, Siena (Italy) at 24/03/2026 20:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 24/03/2026 23:40:00. 50 Basic ticket for £21 per person are available. Travel duration is 3h 10m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Itabus	2h 50m	16:25	Siena	Train Station	19:15	Rome	Tiburtina Bus Station	Premium Economy	£4	A Bus from Itabus goes from Train Station, Siena (Italy) at 25/03/2026 16:25:00 to Tiburtina Bus Station, Rome (Italy) arriving at 25/03/2026 19:15:00. 50 Premium Economy ticket for £4 per person are available. Travel duration is 2h 50m
FlixBus	2h 50m	10:45	Siena	Train Station	13:35	Rome	Tiburtina Bus Station	Economy	£5	A Bus from FlixBus goes from Train Station, Siena (Italy) at 25/03/2026 10:45:00 to Tiburtina Bus Station, Rome (Italy) arriving at 25/03/2026 13:35:00. 50 Economy ticket for £5 per person are available. Travel duration is 2h 50m
FlixBus	2h 45m	18:25	Siena	Train Station	21:10	Rome	Tiburtina Bus Station	Economy	£5	A Bus from FlixBus goes from Train Station, Siena (Italy) at 25/03/2026 18:25:00 to Tiburtina Bus Station, Rome (Italy) arriving at 25/03/2026 21:10:00. 50 Economy ticket for £5 per person are available. Travel duration is 2h 45m
Itabus	2h 50m	13:45	Siena	Train Station	16:35	Rome	Tiburtina Bus Station	Premium Economy	£6	A Bus from Itabus goes from Train Station, Siena (Italy) at 25/03/2026 13:45:00 to Tiburtina Bus Station, Rome (Italy) arriving at 25/03/2026 16:35:00. 50 Premium Economy ticket for £6 per person are available. Travel duration is 2h 50m
MarinoBus	3h 15m	11:05	Siena	Train Station	14:20	Rome	Tiburtina Bus Station	Basic	£11	A Bus from MarinoBus goes from Train Station, Siena (Italy) at 25/03/2026 11:05:00 to Tiburtina Bus Station, Rome (Italy) arriving at 25/03/2026 14:20:00. 50 Basic ticket for £11 per person are available. Travel duration is 3h 15m

Best Price Offer: The price for the cheapest coach from Siena to Rome is £4 on 21/03/2026. Flexible travellers save on ticket prices.

Frequency of bus connections between Siena and Rome

See here how frequent the connections between Siena and Rome are, during different times and days of the week.

Monday is the busiest day, with more than 60 daily coaches from Siena to Rome. Tuesday has instead the fewest connections, with only 8 daily coaches between Siena and Rome.

The busiest time of the day is the Afternoon, with 95 coaches from Siena to Rome, while Night sees the fewest connections between Siena and Rome, with 28 offers.

Facts about coaches from Siena to Rome

Compare all providers like Itabus, FlixBus and MarinoBus that travel 45 times every day by bus from Siena to Rome in one click! Book your bus ticket from Siena to Rome starting from £4!

Cheapest Bus	£4
Fastest Bus	2h 40m
Earliest Coach	05:15
Latest Coach	20:30
Daily Bus Connections	45 Ø
Distance	184.3 km
Coach Companies	Itabus, FlixBus and MarinoBus

Cheapest coach connections from Siena to Rome

Every day, 45 buses from 3 coach companies leave Siena for Rome: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 20/03/2026 and for the following days.

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday

Monday 16/03

Tuesday 17/03

Wednesday 18/03

Thursday 19/03

Friday 20/03

Saturday 21/03

£4

Sunday 22/03

£6

Monday 23/03

£6

Tuesday 24/03

£4

Wednesday 25/03

£4

Thursday 26/03

Friday 27/03

£8

Saturday 28/03

£9

Sunday 29/03

£11

Monday 30/03

£8

Tuesday 31/03

£6

Wednesday 01/04

£9

Thursday 02/04

£11

Friday 03/04

£29

Saturday 04/04

£9

Sunday 05/04

£18

Monday 06/04

£12

Tuesday 07/04

£11

Wednesday 08/04

£6

Thursday 09/04

£11

Friday 10/04

£6

Saturday 11/04

£7

Sunday 12/04

The cheapest time to travel from Siena to Rome

See here on which day and which time of the day you can find the cheapest bus ticket from Siena to Rome, for the next 30 days.

With a price starting from £4, Wednesday is the cheapest day for a coach from Siena to Rome. Monday instead is the most expensive day with prices starting from £6.

Afternoon is the cheapest day time for bus tickets from Siena to Rome, with £4. Morning is the most expensive time of the day with prices starting from £5.

How to save money travelling from Siena to Rome

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Siena to Rome in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Siena to Rome, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Siena to Rome are also emptier.

All bus stations and stops in Siena and Rome

The map below shows you where to find all the bus stations in Siena and Rome.

Piazza Antonio Gramsci

Central Bus Station

Bus Stop

Viale Pietro Toselli 9

Colonna San Marco

Anagnina Bus Station

Piazzale della Stazione Anagnina

Termini Bus Station

Piazza dei Cinquecento 64

Tiburtina Bus Station

Largo Guido Mazzoni 4

Tiburtina Coach Station

Tiburtina Partenze

Vatican City

Via Crescenzio 19

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Siena to Rome? Compare all modes of transports from Siena to Rome.

Service and Comfort on the bus from Siena to Rome

Want to know which seat classes are available on the coaches from Siena to Rome? Or which bus companies serve the route Siena to Rome? Below you will find answers to your questions.

FAQs about the Siena to Rome bus

How much does a Siena - Rome coach trip cost?

This depends on, among other things, the day and travel time. The cheapest ticket for the Siena - Rome bus trip is available from £4 and takes 2h 50m. Compare offers and save money!

How much could I save by comparing buses from Siena to Rome?

The connection Siena to Rome is offered by 3 companies with ticket prices ranging from £4 to £38. Therefore, we suggest booking your ticket as soon as possible to ensure you will get the cheapest ticket price.

How many connections are available for the Siena - Rome route on average every day?

Each day, the bus route from Siena to Rome is offered by roughly 45 busses. By using our search, you can compare bus schedules and find your ideal trip.

How long does a bus to Rome from Siena take?

The quickest coach from Siena to Rome is provided by FlixBus and takes 2h 40m. Coach tickets for this connection cost £7. However, keep in mind that the connection can take longer due to traffic.

What time is the first bus from Siena to Rome?

The earliest bus to Rome departs from Siena at 05:15. In this context, information about departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

What time is the last coach from Siena to Rome?

The latest bus to Rome departs from Siena at 20:30. Please note that departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

Which bus companies serve the Siena - Rome route?

Passengers looking to travel from Siena to Rome can travel with Itabus, FlixBus and MarinoBus. Compare all available bus tickets with our search to book the trip that works best for you.

Is there a direct bus between Siena and Rome?

You can check all the direct connections between Siena and Rome by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Itabus, FlixBus and MarinoBus.

What can I take with me on the bus to Rome from Siena?

Depending on which provider you travel with, what you are allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the bus for the Siena Rome bus route free of charge. Simply use our search to find a coach that is best suited to your needs for your planned travel date.

What equipment is available for the Siena Rome bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make travelling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Siena to Rome on your planned travel date.

How does CheckMyBus find the best bus deals from Siena to Rome?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 45 daily trips between Siena and Rome. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Siena to Rome?

Prices and availability for 45 trips between Siena and Rome change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Siena to Rome

Basic

Name referring to the typical seat you will find with companies that don’t distinguish between different classes.

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

Premium Economy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

More bus routes to Siena and to Rome

Here’s an overview of the most popular bus routes to Siena and to Rome. Simply click on the connection of your choice, and you will find all the details about your bus route!