Bus tickets Pisa to Palermo from £27

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Compare all timetables for the bus from Pisa to Palermo

Here is a selection of the cheapest bus trips from the schedule from Pisa to Palermo from various bus operators like FlixBus for the next days.

today
£63
tomorrow
£42
Thursday
£44
Friday
£39
Saturday
£35
Sunday
£55
Monday
£45

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 21h 35m 13:25 Pisa Pietrasantina Bus Station 11:00 Palermo Via Tommaso Fazello Bus Stop  Economy £63
FlixBus 22h 5m 17:10 Pisa Pietrasantina Bus Station 15:15 Palermo Via Tommaso Fazello Bus Stop  Economy £69
FlixBus 28h 55m 06:05 Pisa Parking Aurelia 11:00 Palermo Via Tommaso Fazello Bus Stop  Economy £81
  • Did you know that if you travel from Pisa to Palermo via Rome, you can save more than £17? You can find the corresponding connections below.
    • FlixBus
      24h 30m
      0
      07:15
      Pisa
      Pietrasantina Bus Station
      13:15
      Rome
      Anagnina Bus Station
      0
      FlixBus
      Economy
      £20
      • Waiting Time 6h 45m
    • Autoservizi Salemi
      11h 45m
      0
      20:00
      Rome
      Tiburtina Coach Station
      07:45
      Palermo
      Via Tommaso Fazello Bus Stop
      0
      Autoservizi Salemi
      Economy
      £26
    Travel time is 2h 55m longer, but you will save £17

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 27h 45m 07:15 Pisa Pietrasantina Bus Station 11:00 Palermo Via Tommaso Fazello Bus Stop  Economy £42
FlixBus 22h 5m 17:10 Pisa Pietrasantina Bus Station 15:15 Palermo Via Tommaso Fazello Bus Stop  Economy £47
FlixBus 29h 15m 05:45 Pisa Parking Aurelia 11:00 Palermo Via Tommaso Fazello Bus Stop  Economy £48
  • Did you know that if you travel from Pisa to Palermo via Rome, you can save more than £6? You can find the corresponding connections below.
    • FlixBus
      19h 50m
      0
      12:00
      Pisa
      Pietrasantina Bus Station
      17:50
      Rome
      Anagnina Bus Station
      0
      FlixBus
      Economy
      £13
      • Waiting Time 0h 25m
    • Itabus
      13h 35m
      0
      18:15
      Rome
      Tiburtina Coach Station
      07:50
      Palermo
      Via Tommaso Fazello Bus Stop
      0
      Itabus
      Economy
      £22
    Travel Time is 2h 15m shorter, and you will save £6

Cheapest bus trips Thursday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 21h 50m 17:25 Pisa Pietrasantina Bus Station 15:15 Palermo Via Tommaso Fazello Bus Stop  Economy £44
FlixBus 23h 0m 12:00 Pisa Pietrasantina Bus Station 11:00 Palermo Via Tommaso Fazello Bus Stop  Economy £45
FlixBus 28h 55m 06:05 Pisa Parking Aurelia 11:00 Palermo Via Tommaso Fazello Bus Stop  Economy £50
FlixBus 19h 0m 00:25 Pisa Pietrasantina Bus Station 19:25 Palermo Via Tommaso Fazello Bus Stop  Economy £67
  • Did you know that if you travel from Pisa to Palermo via Rome, you can save more than £8? You can find the corresponding connections below.
    • FlixBus
      19h 50m
      0
      12:00
      Pisa
      Pietrasantina Bus Station
      17:50
      Rome
      Anagnina Bus Station
      0
      FlixBus
      Economy
      £13
      • Waiting Time 0h 25m
    • Itabus
      13h 35m
      0
      18:15
      Rome
      Tiburtina Coach Station
      07:50
      Palermo
      Via Tommaso Fazello Bus Stop
      0
      Itabus
      Economy
      £22
    Travel time is 0h 50m longer, but you will save £8

Cheapest bus trips Friday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 21h 35m 13:25 Pisa Pietrasantina Bus Station 11:00 Palermo Via Tommaso Fazello Bus Stop  Economy £39
FlixBus 28h 55m 06:05 Pisa Parking Aurelia 11:00 Palermo Via Tommaso Fazello Bus Stop  Economy £46
FlixBus 21h 50m 17:25 Pisa Pietrasantina Bus Station 15:15 Palermo Via Tommaso Fazello Bus Stop  Economy £54
  • Did you know that if you travel from Pisa to Palermo via Rome, you can save more than £6? You can find the corresponding connections below.
    • FlixBus
      22h 10m
      0
      09:40
      Pisa
      Pietrasantina Bus Station
      16:05
      Rome
      Tiburtina Bus Station
      0
      FlixBus
      Economy
      £13
      • Waiting Time 2h 10m
    • Itabus
      13h 35m
      0
      18:15
      Rome
      Tiburtina Bus Station
      07:50
      Palermo
      Via Fazello
      0
      Itabus
      Premium Economy
      £20
    Travel time is 0h 35m longer, but you will save £6

Cheapest bus trips Saturday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 21h 35m 13:25 Pisa Pietrasantina Bus Station 11:00 Palermo Via Tommaso Fazello Bus Stop  Economy £35
FlixBus 28h 55m 06:05 Pisa Parking Aurelia 11:00 Palermo Via Tommaso Fazello Bus Stop  Economy £42
FlixBus 21h 50m 17:25 Pisa Pietrasantina Bus Station 15:15 Palermo Via Tommaso Fazello Bus Stop  Economy £42
FlixBus 21h 25m 22:00 Pisa Pietrasantina Bus Station 19:25 Palermo Via Tommaso Fazello Bus Stop  Economy £66

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 21h 35m 13:25 Pisa Pietrasantina Bus Station 11:00 Palermo Via Tommaso Fazello Bus Stop  Economy £55
FlixBus 21h 50m 17:25 Pisa Pietrasantina Bus Station 15:15 Palermo Via Tommaso Fazello Bus Stop  Economy £57
FlixBus 28h 55m 06:05 Pisa Parking Aurelia 11:00 Palermo Via Tommaso Fazello Bus Stop  Economy £63
FlixBus 19h 0m 00:25 Pisa Parking Aurelia 19:25 Palermo Via Tommaso Fazello Bus Stop  Economy £72
  • Did you know that if you travel from Pisa to Palermo via Rome, you can save more than £22? You can find the corresponding connections below.
    • FlixBus
      22h 10m
      0
      09:40
      Pisa
      Pietrasantina Bus Station
      16:05
      Rome
      Tiburtina Bus Station
      0
      FlixBus
      Economy
      £13
      • Waiting Time 2h 10m
    • Itabus
      13h 35m
      0
      18:15
      Rome
      Tiburtina Bus Station
      07:50
      Palermo
      Via Fazello
      0
      Itabus
      Premium Economy
      £20
    Travel time is 3h 10m longer, but you will save £22

Cheapest bus trips Monday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 21h 35m 13:25 Pisa Pietrasantina Bus Station 11:00 Palermo Via Tommaso Fazello Bus Stop  Economy £45
FlixBus 28h 55m 06:05 Pisa Parking Aurelia 11:00 Palermo Via Tommaso Fazello Bus Stop  Economy £48
FlixBus 21h 50m 17:25 Pisa Pietrasantina Bus Station 15:15 Palermo Via Tommaso Fazello Bus Stop  Economy £49
  • Did you know that if you travel from Pisa to Palermo via Rome, you can save more than £12? You can find the corresponding connections below.
    • FlixBus
      22h 10m
      0
      09:40
      Pisa
      Pietrasantina Bus Station
      16:05
      Rome
      Tiburtina Bus Station
      0
      FlixBus
      Economy
      £13
      • Waiting Time 2h 10m
    • Itabus
      13h 35m
      0
      18:15
      Rome
      Tiburtina Bus Station
      07:50
      Palermo
      Via Fazello
      0
      Itabus
      Premium Economy
      £20
    Travel time is 0h 35m longer, but you will save £12

Best Price Offer: The price for the cheapest coach from Pisa to Palermo is £27 on 28/09/2026. Flexible travellers save on ticket prices.


Frequency of bus connections between Pisa and Palermo

See here how frequent the connections between Pisa and Palermo are, during different times and days of the week.
Monday is the busiest day, with more than 4 daily coaches from Pisa to Palermo. Tuesday has instead the fewest connections, with only 3 daily coaches between Pisa and Palermo.
The busiest time of the day is the Afternoon, with 15 coaches from Pisa to Palermo, while Evening sees the fewest connections between Pisa and Palermo, with 1 offers.

Facts about coaches from Pisa to Palermo

Compare all providers like FlixBus that travel 3 times every day by bus from Pisa to Palermo in one click! Book your bus ticket from Pisa to Palermo starting from £27!

Cheapest Bus £27
Fastest Bus 19h 0m
Earliest Coach 06:05
Latest Coach 17:25
Daily Bus Connections 3 Ø
Distance 671.1 km
Coach Companies FlixBus

Cheapest coach connections from Pisa to Palermo

Every day, 3 buses from 1 coach companies leave Pisa for Palermo: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 08/09/2026 and for the following days.

Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday
Monday 07/09
Tuesday 08/09
£63
Wednesday 09/09
£42
Thursday 10/09
£44
Friday 11/09
£39
Saturday 12/09
£35
Sunday 13/09
£55
Monday 14/09
£45
Tuesday 15/09
£45
Wednesday 16/09
£45
Thursday 17/09
£39
Friday 18/09
£35
Saturday 19/09
£41
Sunday 20/09
£44
Monday 21/09
£41
Tuesday 22/09
£38
Wednesday 23/09
£39
Thursday 24/09
£41
Friday 25/09
£40
Saturday 26/09
£32
Sunday 27/09
£32
Monday 28/09
£27
Tuesday 29/09
£37
Wednesday 30/09
£50
Thursday 01/10
£60
Friday 02/10
£51
Saturday 03/10
£44
Sunday 04/10

The cheapest time to travel from Pisa to Palermo

See here on which day and which time of the day you can find the cheapest bus ticket from Pisa to Palermo, for the next 30 days.
With a price starting from £27, Monday is the cheapest day for a coach from Pisa to Palermo. Wednesday instead is the most expensive day with prices starting from £39.
Night is the cheapest day time for bus tickets from Pisa to Palermo, with £27. Evening is the most expensive time of the day with prices starting from £66.

How to save money travelling from Pisa to Palermo

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Pisa to Palermo in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Pisa to Palermo, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Pisa to Palermo are also emptier.

All bus stations and stops in Pisa and Palermo

The map below shows you where to find all the bus stations in Pisa and Palermo.

Service and Comfort on the bus from Pisa to Palermo

Want to know which seat classes are available on the coaches from Pisa to Palermo? Or which bus companies serve the route Pisa to Palermo? Below you will find answers to your questions.

FAQs about the Pisa to Palermo bus

How much does a Pisa - Palermo coach trip cost?

This depends on, among other things, the day and travel time. The cheapest ticket for the Pisa - Palermo bus trip is available from £27 and takes 21h 35m. Compare offers and save money!

How much could I save by comparing buses from Pisa to Palermo?

The connection Pisa to Palermo is offered by 1 companies with ticket prices ranging from £27 to £81. Therefore, we suggest booking your ticket as soon as possible to ensure you will get the cheapest ticket price.

How many connections are available for the Pisa - Palermo route on average every day?

Each day, the bus route from Pisa to Palermo is offered by roughly 3 busses. By using our search, you can compare bus schedules and find your ideal trip.

How long does a bus to Palermo from Pisa take?

The quickest coach from Pisa to Palermo is provided by FlixBus and takes 19h 0m. Coach tickets for this connection cost £67. However, keep in mind that the connection can take longer due to traffic.

What time is the first bus from Pisa to Palermo?

The earliest bus to Palermo departs from Pisa at 06:05. In this context, information about departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

What time is the last coach from Pisa to Palermo?

The latest bus to Palermo departs from Pisa at 17:25. Please note that departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

Which bus companies serve the Pisa - Palermo route?

Passengers looking to travel from Pisa to Palermo can travel with FlixBus. Compare all available bus tickets with our search to book the trip that works best for you.

Is there a direct bus between Pisa and Palermo?

You can check all the direct connections between Pisa and Palermo by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus.

What can I take with me on the bus to Palermo from Pisa?

Depending on which provider you travel with, what you are allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the bus for the Pisa Palermo bus route free of charge. Simply use our search to find a coach that is best suited to your needs for your planned travel date.

What equipment is available for the Pisa Palermo bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make travelling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Pisa to Palermo on your planned travel date.

How does CheckMyBus find the best bus deals from Pisa to Palermo?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 3 daily trips between Pisa and Palermo. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Pisa to Palermo?

Prices and availability for 3 trips between Pisa and Palermo change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Pisa to Palermo

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Pisa and to Palermo

Here’s an overview of the most popular bus routes to Pisa and to Palermo. Simply click on the connection of your choice, and you will find all the details about your bus route!
Coach from Perugia to Pisa Coach from Perugia to Pisa
Bus Sesto San Giovanni to Pisa Bus Sesto San Giovanni to Pisa
Coaches Arezzo to Pisa Coaches Arezzo to Pisa
Coach to Pisa from Chieti Coach to Pisa from Chieti
Coach Acireale to Palermo Coach Acireale to Palermo
Bus from Villa San Giovanni to Palermo Bus from Villa San Giovanni to Palermo
Coaches Milazzo to Palermo Coaches Milazzo to Palermo
Buses Castelvetrano to Palermo Buses Castelvetrano to Palermo
Popular Airport Transfers to Pisa and to Palermo
CheckMyBus › Coaches in Italy › Coach to Pisa › Coach to Palermo

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