Which bus from Messina to Rome is the best?
Check the bus schedule for Messina to Rome. Here is a selection of the cheapest coach trips for the next days from bus operators like Itabus, FlixBus or Autoservizi Salemi. To see the full timetable for all coaches just use or search and compare.
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 14h 30m | 23:50 | Messina | Piazza della Repubblica | 14:20 | Rome | Tiburtina Coach Station | Economy | £21 |
A Bus from Itabus goes from Piazza della Repubblica, Messina (Italy) at 30/07/2026 23:50:00 to Tiburtina Coach Station, Rome (Italy) arriving at 31/07/2026 14:20:00. 50 Economy ticket for £21 per person are available. Travel duration is 14h 30m
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| Itabus | 10h 10m | 21:35 | Messina | Piazza della Repubblica | 07:45 | Rome | Tiburtina Coach Station | Economy | £22 |
A Bus from Itabus goes from Piazza della Repubblica, Messina (Italy) at 30/07/2026 21:35:00 to Tiburtina Coach Station, Rome (Italy) arriving at 31/07/2026 07:45:00. 50 Economy ticket for £22 per person are available. Travel duration is 10h 10m
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| FlixBus | 10h 35m | 10:55 | Messina | Piazza della Repubblica | 21:30 | Rome | Tiburtina Bus Station | Economy | £23 |
A Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 30/07/2026 10:55:00 to Tiburtina Bus Station, Rome (Italy) arriving at 30/07/2026 21:30:00. 50 Economy ticket for £23 per person are available. Travel duration is 10h 35m
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| FlixBus | 10h 0m | 01:30 | Messina | Piazza della Repubblica | 11:30 | Rome | Tiburtina Bus Station | Economy | £25 |
A Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 30/07/2026 01:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 30/07/2026 11:30:00. 50 Economy ticket for £25 per person are available. Travel duration is 10h 0m
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| Autoservizi Salemi | 9h 0m | 21:15 | Messina | Piazza della Repubblica | 06:15 | Rome | Tiburtina Coach Station | Economy | £39 |
A Bus from Autoservizi Salemi goes from Piazza della Repubblica, Messina (Italy) at 30/07/2026 21:15:00 to Tiburtina Coach Station, Rome (Italy) arriving at 31/07/2026 06:15:00. 50 Economy ticket for £39 per person are available. Travel duration is 9h 0m
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Itabus11h 0m010:20MessinaPiazza della Repubblica18:00NaplesMetropark Centrale0EconomyA Bus from Itabus goes from Piazza della Repubblica, Messina (Italy) at 31/07/2026 10:20:00 to Metropark Centrale, Naples (Italy) arriving at 31/07/2026 18:00:00. 50 Economy ticket for £15 per person are available. Travel duration is 7h 40m
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Itabus2h 40m018:40NaplesMetropark Centrale21:20RomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Metropark Centrale, Naples (Italy) at 31/07/2026 18:40:00 to Tiburtina Bus Station, Rome (Italy) arriving at 31/07/2026 21:20:00. 50 Premium Economy ticket for £4 per person are available. Travel duration is 2h 40m
Waiting Time 0h 40m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 14h 30m | 23:50 | Messina | Central Station | 14:20 | Rome | Tiburtina Bus Station | Premium Economy | £18 |
A Bus from Itabus goes from Central Station, Messina (Italy) at 31/07/2026 23:50:00 to Tiburtina Bus Station, Rome (Italy) arriving at 01/08/2026 14:20:00. 50 Premium Economy ticket for £18 per person are available. Travel duration is 14h 30m
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| Itabus | 10h 10m | 21:35 | Messina | Central Station | 07:45 | Rome | Tiburtina Bus Station | Premium Economy | £20 |
A Bus from Itabus goes from Central Station, Messina (Italy) at 31/07/2026 21:35:00 to Tiburtina Bus Station, Rome (Italy) arriving at 01/08/2026 07:45:00. 50 Premium Economy ticket for £20 per person are available. Travel duration is 10h 10m
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| FlixBus | 9h 20m | 21:30 | Messina | Piazza della Repubblica | 06:50 | Rome | Tiburtina Bus Station | Economy | £22 |
A Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 31/07/2026 21:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 01/08/2026 06:50:00. 50 Economy ticket for £22 per person are available. Travel duration is 9h 20m
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| FlixBus | 10h 0m | 01:30 | Messina | Piazza della Repubblica | 11:30 | Rome | Tiburtina Bus Station | Economy | £23 |
A Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 31/07/2026 01:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 31/07/2026 11:30:00. 50 Economy ticket for £23 per person are available. Travel duration is 10h 0m
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| Autoservizi Salemi | 9h 0m | 21:15 | Messina | Piazza della Repubblica | 06:15 | Rome | Tiburtina Coach Station | Economy | £51 |
A Bus from Autoservizi Salemi goes from Piazza della Repubblica, Messina (Italy) at 31/07/2026 21:15:00 to Tiburtina Coach Station, Rome (Italy) arriving at 01/08/2026 06:15:00. 50 Economy ticket for £51 per person are available. Travel duration is 9h 0m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 10h 10m | 21:35 | Messina | Central Station | 07:45 | Rome | Tiburtina Bus Station | Premium Economy | £18 |
A Bus from Itabus goes from Central Station, Messina (Italy) at 01/08/2026 21:35:00 to Tiburtina Bus Station, Rome (Italy) arriving at 02/08/2026 07:45:00. 50 Premium Economy ticket for £18 per person are available. Travel duration is 10h 10m
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| Itabus | 10h 5m | 23:20 | Messina | Central Station | 09:25 | Rome | Tiburtina Bus Station | Premium Economy | £18 |
A Bus from Itabus goes from Central Station, Messina (Italy) at 01/08/2026 23:20:00 to Tiburtina Bus Station, Rome (Italy) arriving at 02/08/2026 09:25:00. 50 Premium Economy ticket for £18 per person are available. Travel duration is 10h 5m
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| FlixBus | 9h 20m | 21:30 | Messina | Piazza della Repubblica | 06:50 | Rome | Tiburtina Bus Station | Economy | £21 |
A Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 01/08/2026 21:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 02/08/2026 06:50:00. 50 Economy ticket for £21 per person are available. Travel duration is 9h 20m
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| FlixBus | 10h 0m | 01:30 | Messina | Piazza della Repubblica | 11:30 | Rome | Tiburtina Bus Station | Economy | £22 |
A Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 01/08/2026 01:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 01/08/2026 11:30:00. 50 Economy ticket for £22 per person are available. Travel duration is 10h 0m
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| Autoservizi Salemi | 9h 0m | 21:15 | Messina | Piazza della Repubblica | 06:15 | Rome | Tiburtina Bus Station | Economy | £51 |
A Bus from Autoservizi Salemi goes from Piazza della Repubblica, Messina (Italy) at 01/08/2026 21:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 02/08/2026 06:15:00. 50 Economy ticket for £51 per person are available. Travel duration is 9h 0m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 14h 30m | 23:50 | Messina | Central Station | 14:20 | Rome | Tiburtina Bus Station | Premium Economy | £18 |
A Bus from Itabus goes from Central Station, Messina (Italy) at 02/08/2026 23:50:00 to Tiburtina Bus Station, Rome (Italy) arriving at 03/08/2026 14:20:00. 50 Premium Economy ticket for £18 per person are available. Travel duration is 14h 30m
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| FlixBus | 10h 0m | 01:30 | Messina | Piazza della Repubblica | 11:30 | Rome | Tiburtina Bus Station | Economy | £22 |
A Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 02/08/2026 01:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 02/08/2026 11:30:00. 50 Economy ticket for £22 per person are available. Travel duration is 10h 0m
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| Itabus | 10h 10m | 21:35 | Messina | Central Station | 07:45 | Rome | Tiburtina Bus Station | Premium Economy | £23 |
A Bus from Itabus goes from Central Station, Messina (Italy) at 02/08/2026 21:35:00 to Tiburtina Bus Station, Rome (Italy) arriving at 03/08/2026 07:45:00. 50 Premium Economy ticket for £23 per person are available. Travel duration is 10h 10m
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| FlixBus | 9h 20m | 21:30 | Messina | Piazza della Repubblica | 06:50 | Rome | Tiburtina Bus Station | Economy | £33 |
A Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 02/08/2026 21:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 03/08/2026 06:50:00. 50 Economy ticket for £33 per person are available. Travel duration is 9h 20m
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| Autoservizi Salemi | 9h 0m | 21:15 | Messina | Piazza della Repubblica | 06:15 | Rome | Tiburtina Coach Station | Economy | £44 |
A Bus from Autoservizi Salemi goes from Piazza della Repubblica, Messina (Italy) at 02/08/2026 21:15:00 to Tiburtina Coach Station, Rome (Italy) arriving at 03/08/2026 06:15:00. 50 Economy ticket for £44 per person are available. Travel duration is 9h 0m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 10h 10m | 21:35 | Messina | Central Station | 07:45 | Rome | Tiburtina Bus Station | Premium Economy | £18 |
A Bus from Itabus goes from Central Station, Messina (Italy) at 03/08/2026 21:35:00 to Tiburtina Bus Station, Rome (Italy) arriving at 04/08/2026 07:45:00. 50 Premium Economy ticket for £18 per person are available. Travel duration is 10h 10m
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| Itabus | 14h 30m | 23:50 | Messina | Central Station | 14:20 | Rome | Tiburtina Bus Station | Premium Economy | £18 |
A Bus from Itabus goes from Central Station, Messina (Italy) at 03/08/2026 23:50:00 to Tiburtina Bus Station, Rome (Italy) arriving at 04/08/2026 14:20:00. 50 Premium Economy ticket for £18 per person are available. Travel duration is 14h 30m
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| FlixBus | 9h 20m | 21:30 | Messina | Piazza della Repubblica | 06:50 | Rome | Tiburtina Bus Station | Economy | £22 |
A Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 03/08/2026 21:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 04/08/2026 06:50:00. 50 Economy ticket for £22 per person are available. Travel duration is 9h 20m
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| FlixBus | 10h 0m | 01:30 | Messina | Piazza della Repubblica | 11:30 | Rome | Tiburtina Bus Station | Economy | £24 |
A Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 03/08/2026 01:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 03/08/2026 11:30:00. 50 Economy ticket for £24 per person are available. Travel duration is 10h 0m
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| Autoservizi Salemi | 9h 0m | 21:15 | Messina | Piazza della Repubblica | 06:15 | Rome | Tiburtina Coach Station | Economy | £34 |
A Bus from Autoservizi Salemi goes from Piazza della Repubblica, Messina (Italy) at 03/08/2026 21:15:00 to Tiburtina Coach Station, Rome (Italy) arriving at 04/08/2026 06:15:00. 50 Economy ticket for £34 per person are available. Travel duration is 9h 0m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 10h 5m | 23:20 | Messina | Central Station | 09:25 | Rome | Tiburtina Bus Station | Premium Economy | £17 |
A Bus from Itabus goes from Central Station, Messina (Italy) at 04/08/2026 23:20:00 to Tiburtina Bus Station, Rome (Italy) arriving at 05/08/2026 09:25:00. 50 Premium Economy ticket for £17 per person are available. Travel duration is 10h 5m
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| Itabus | 14h 30m | 23:50 | Messina | Central Station | 14:20 | Rome | Tiburtina Bus Station | Premium Economy | £17 |
A Bus from Itabus goes from Central Station, Messina (Italy) at 04/08/2026 23:50:00 to Tiburtina Bus Station, Rome (Italy) arriving at 05/08/2026 14:20:00. 50 Premium Economy ticket for £17 per person are available. Travel duration is 14h 30m
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| Itabus | 10h 10m | 21:35 | Messina | Central Station | 07:45 | Rome | Tiburtina Bus Station | Premium Economy | £20 |
A Bus from Itabus goes from Central Station, Messina (Italy) at 04/08/2026 21:35:00 to Tiburtina Bus Station, Rome (Italy) arriving at 05/08/2026 07:45:00. 50 Premium Economy ticket for £20 per person are available. Travel duration is 10h 10m
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| FlixBus | 9h 20m | 21:30 | Messina | Piazza della Repubblica | 06:50 | Rome | Tiburtina Bus Station | Economy | £22 |
A Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 04/08/2026 21:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 05/08/2026 06:50:00. 50 Economy ticket for £22 per person are available. Travel duration is 9h 20m
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| FlixBus | 10h 0m | 01:30 | Messina | Piazza della Repubblica | 11:30 | Rome | Tiburtina Bus Station | Economy | £23 |
A Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 04/08/2026 01:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 04/08/2026 11:30:00. 50 Economy ticket for £23 per person are available. Travel duration is 10h 0m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 14h 30m | 23:50 | Messina | Central Station | 14:20 | Rome | Tiburtina Bus Station | Premium Economy | £17 |
A Bus from Itabus goes from Central Station, Messina (Italy) at 05/08/2026 23:50:00 to Tiburtina Bus Station, Rome (Italy) arriving at 06/08/2026 14:20:00. 50 Premium Economy ticket for £17 per person are available. Travel duration is 14h 30m
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| Itabus | 10h 10m | 21:35 | Messina | Central Station | 07:45 | Rome | Tiburtina Bus Station | Premium Economy | £20 |
A Bus from Itabus goes from Central Station, Messina (Italy) at 05/08/2026 21:35:00 to Tiburtina Bus Station, Rome (Italy) arriving at 06/08/2026 07:45:00. 50 Premium Economy ticket for £20 per person are available. Travel duration is 10h 10m
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| FlixBus | 10h 0m | 01:30 | Messina | Piazza della Repubblica | 11:30 | Rome | Tiburtina Bus Station | Economy | £21 |
A Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 05/08/2026 01:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 05/08/2026 11:30:00. 50 Economy ticket for £21 per person are available. Travel duration is 10h 0m
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| FlixBus | 9h 20m | 21:30 | Messina | Piazza della Repubblica | 06:50 | Rome | Tiburtina Bus Station | Economy | £22 |
A Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 05/08/2026 21:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 06/08/2026 06:50:00. 50 Economy ticket for £22 per person are available. Travel duration is 9h 20m
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| Autoservizi Salemi | 9h 0m | 21:15 | Messina | Piazza della Repubblica | 06:15 | Rome | Tiburtina Coach Station | Economy | £52 |
A Bus from Autoservizi Salemi goes from Piazza della Repubblica, Messina (Italy) at 05/08/2026 21:15:00 to Tiburtina Coach Station, Rome (Italy) arriving at 06/08/2026 06:15:00. 50 Economy ticket for £52 per person are available. Travel duration is 9h 0m
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FlixBus13h 20m021:30MessinaPiazza della Repubblica04:05NaplesMetropark Centrale0EconomyA Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 06/08/2026 21:30:00 to Metropark Centrale, Naples (Italy) arriving at 07/08/2026 04:05:00. 50 Economy ticket for £9 per person are available. Travel duration is 6h 35m
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Itabus3h 5m007:45NaplesMetropark Centrale10:50RomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Metropark Centrale, Naples (Italy) at 07/08/2026 07:45:00 to Tiburtina Bus Station, Rome (Italy) arriving at 07/08/2026 10:50:00. 50 Premium Economy ticket for £5 per person are available. Travel duration is 3h 5m
Waiting Time 3h 40m -
Best Price Offer: The price for the cheapest coach from Messina to Rome is £11 on 06/08/2026. Flexible travellers save on ticket prices.
What is the best day and time to travel by bus between Messina and Rome?
All facts for Messina to Rome bus at a glance
Compare all coach operators like Itabus, FlixBus and Autoservizi Salemi that travel daily 20 times by bus from Messina to Rome in one click. Book your Messina to Rome bus ticket starting from £11!
| Cheapest Bus | £11 |
| Fastest Bus | 9h 0m |
| Earliest Coach | 01:30 |
| Latest Coach | 23:50 |
| Daily Bus Connections | 20 Ø |
| Distance | 487.4 km |
| Coach Companies | Itabus, FlixBus and Autoservizi Salemi |
What are the cheapest coach tickets from Messina to Rome?
Every day, 20 buses from 3 coach companies leave Messina for Rome. Check the table below to find the cheapest prices for coach tickets for this route, starting from 30/07/2026 and for the following days. Make sure get the cheapest bus ticket!
The cheapest time to travel from Messina to Rome
How to save money travelling from Messina to Rome
Book the ticket from Messina to Rome in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the coach from Messina to Rome, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Messina to Rome are also emptier.Check for bus deals and promotions for all bus companies in this route. On CheckMyBus we show special offers directly in the coach trip on our search. Sign-up and check or deals sections and get notifications on our latest travel hacks.
All bus stations and stops in Messina and Rome
Here is a map with all coach stations in Messina and Rome. Compare which stop is closest to your destination to save time to find the fastest buses and connections.
All you need to know when you travel by bus from Messina to Rome
FAQs for Messina to Rome bus
How much does a Messina Rome coach trip cost?
How much could I save by comparing buses from Messina to Rome?
How many connections are available for the Messina Rome route on average every day?
How long does a bus to Rome from Messina take?
What time is the first bus from Messina to Rome?
What time is the last coach from Messina to Rome?
Which bus companies serve the Messina Rome route?
Is there a direct bus between Messina and Rome?
What can I take with me on the bus to Rome from Messina?
What equipment is available for the Messina Rome bus route?
How does CheckMyBus find the best coach deals from Messina to Rome?
How does CheckMyBus technology work for trips from Messina to Rome?
Available seat classes which are offered on the bus route Messina to Rome
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.
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