Coach Isernia to Rome from £15

Which bus from Isernia to Rome is the best?

Check the bus schedule for Isernia to Rome. Here is a selection of the cheapest coach trips for the next days from bus operators like FlixBus. To see the full timetable for all coaches just use or search and compare.

today

£20

tomorrow

£23

Sunday

Monday

£37

Tuesday

Wednesday

£21

Thursday

Cheapest bus trips today
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	6h 55m	15:50	Isernia	Central Bus Station	22:45	Rome	Tiburtina Bus Station		Economy	£20	A Bus from FlixBus goes from Central Bus Station, Isernia (Italy) at 05/12/2025 15:50:00 to Tiburtina Bus Station, Rome (Italy) arriving at 05/12/2025 22:45:00. 50 Economy ticket for £20 per person are available. Travel duration is 6h 55m
	FlixBus	9h 5m	11:25	Isernia	Central Bus Station	20:30	Rome	Tiburtina Bus Station		Economy	£39	A Bus from FlixBus goes from Central Bus Station, Isernia (Italy) at 05/12/2025 11:25:00 to Tiburtina Bus Station, Rome (Italy) arriving at 05/12/2025 20:30:00. 50 Economy ticket for £39 per person are available. Travel duration is 9h 5m

Cheapest bus trips tomorrow
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	6h 55m	15:50	Isernia	Central Bus Station	22:45	Rome	Tiburtina Bus Station		Economy	£23	A Bus from FlixBus goes from Central Bus Station, Isernia (Italy) at 06/12/2025 15:50:00 to Tiburtina Bus Station, Rome (Italy) arriving at 06/12/2025 22:45:00. 50 Economy ticket for £23 per person are available. Travel duration is 6h 55m
	FlixBus	9h 5m	11:25	Isernia	Central Bus Station	20:30	Rome	Tiburtina Bus Station		Economy	£28	A Bus from FlixBus goes from Central Bus Station, Isernia (Italy) at 06/12/2025 11:25:00 to Tiburtina Bus Station, Rome (Italy) arriving at 06/12/2025 20:30:00. 50 Economy ticket for £28 per person are available. Travel duration is 9h 5m

Cheapest bus trips Monday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	9h 5m	11:25	Isernia	Central Bus Station	20:30	Rome	Tiburtina Bus Station		Economy	£37	A Bus from FlixBus goes from Central Bus Station, Isernia (Italy) at 08/12/2025 11:25:00 to Tiburtina Bus Station, Rome (Italy) arriving at 08/12/2025 20:30:00. 50 Economy ticket for £37 per person are available. Travel duration is 9h 5m
	FlixBus	7h 5m	15:50	Isernia	Central Bus Station	22:55	Rome	Tiburtina Bus Station		Economy	£54	A Bus from FlixBus goes from Central Bus Station, Isernia (Italy) at 08/12/2025 15:50:00 to Tiburtina Bus Station, Rome (Italy) arriving at 08/12/2025 22:55:00. 50 Economy ticket for £54 per person are available. Travel duration is 7h 5m

Did you know that if you travel from Isernia to Rome via Caserta, you can save more than £8? You can find the corresponding connections below.
- FlixBus
  
  7h 45m
  
  0
  
  15:50
  
  Isernia
  Central Bus Station
  
  17:05
  
  Caserta
  Train Station
  
  0
  
  Economy
  
  £14
  
  A Bus from FlixBus goes from Central Bus Station, Isernia (Italy) at 08/12/2025 15:50:00 to Train Station, Caserta (Italy) arriving at 08/12/2025 17:05:00. 50 Economy ticket for £14 per person are available. Travel duration is 1h 15m
- Distribusion
  
  2h 34m
  
  0
  
  21:01
  
  Caserta
  Train Station
  
  23:35
  
  Rome
  Tiburtina Bus Station
  
  0
  
  Premium Economy
  
  £15
  
  A Bus from Distribusion goes from Train Station, Caserta (Italy) at 08/12/2025 21:01:00 to Tiburtina Bus Station, Rome (Italy) arriving at 08/12/2025 23:35:00. 50 Premium Economy ticket for £15 per person are available. Travel duration is 2h 34m
Travel time is 0h 40m longer, but you will save £8

Cheapest bus trips Wednesday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	6h 55m	15:50	Isernia	Central Bus Station	22:45	Rome	Tiburtina Bus Station		Economy	£21	A Bus from FlixBus goes from Central Bus Station, Isernia (Italy) at 10/12/2025 15:50:00 to Tiburtina Bus Station, Rome (Italy) arriving at 10/12/2025 22:45:00. 50 Economy ticket for £21 per person are available. Travel duration is 6h 55m

Best Price Offer: The price for the cheapest coach from Isernia to Rome is £15 on 02/12/2025. Flexible travellers save on ticket prices.

What is the best day and time to travel by bus between Isernia and Rome?

Here is the frequency of all coach connections from Isernia to Rome. See on which day of the week you have more travel options and what time you have more bus trips to choose from.

Monday is the busiest day, with more than 2 daily coaches from Isernia to Rome. Wednesday has instead the fewest connections, with only 1 daily coaches between Isernia and Rome.

The busiest time of the day is the Afternoon, with 4 coaches from Isernia to Rome, while Morning sees the fewest connections between Isernia and Rome, with 3 offers.

All facts for Isernia to Rome bus at a glance

Compare all coach operators like FlixBus that travel daily 1 times by bus from Isernia to Rome in one click. Book your Isernia to Rome bus ticket starting from £15!

Cheapest Bus	£15
Fastest Bus	6h 55m
Earliest Coach	11:25
Latest Coach	15:50
Daily Bus Connections	1 Ø
Distance	147.8 km
Coach Companies	FlixBus

What are the cheapest coach tickets from Isernia to Rome?

Every day, 1 buses from 1 coach companies leave Isernia for Rome. Check the table below to find the cheapest prices for coach tickets for this route, starting from 05/12/2025 and for the following days. Make sure get the cheapest bus ticket!

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday

Monday 01/12

Tuesday 02/12

Wednesday 03/12

Thursday 04/12

Friday 05/12

£20

Saturday 06/12

£23

Sunday 07/12

Monday 08/12

£37

Tuesday 09/12

Wednesday 10/12

£21

Thursday 11/12

Friday 12/12

Saturday 13/12

Sunday 14/12

£28

Monday 15/12

Tuesday 16/12

Wednesday 17/12

Thursday 18/12

Friday 19/12

Saturday 20/12

Sunday 21/12

Monday 22/12

Tuesday 23/12

Wednesday 24/12

Thursday 25/12

Friday 26/12

Saturday 27/12

Sunday 28/12

The cheapest time to travel from Isernia to Rome

See here on which day and which time of the day you can find the cheapest bus ticket from Isernia to Rome, for the next 30 days.

With a price starting from £20, Friday is the cheapest day for a coach from Isernia to Rome. Monday instead is the most expensive day with prices starting from £37.

Afternoon is the cheapest day time for bus tickets from Isernia to Rome, with £20. Morning is the most expensive time of the day with prices starting from £28.

How to save money travelling from Isernia to Rome

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying higher prices for your trip? Plan your bus trips smartly. Here are a few hacks to save money on your coach journey.

Book the ticket from Isernia to Rome in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the coach from Isernia to Rome, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Isernia to Rome are also emptier.

Check for bus deals and promotions for all bus companies in this route. On CheckMyBus we show special offers directly in the coach trip on our search. Sign-up and check or deals sections and get notifications on our latest travel hacks.

All bus stations and stops in Isernia and Rome

Here is a map with all coach stations in Isernia and Rome. Compare which stop is closest to your destination to save time to find the fastest buses and connections.

Central Bus Station

Train Station

Anagnina Bus Station

Piazzale della Stazione Anagnina

Termini Bus Station

Piazza dei Cinquecento 64

Tiburtina Bus Station

Largo Guido Mazzoni 4

Tiburtina Coach Station

Tiburtina Partenze

Vatican City

Via Crescenzio 19

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Isernia to Rome? Compare all modes of transports from Isernia to Rome.

All you need to know when you travel by bus from Isernia to Rome

Check all information on comfort and services on the coaches from Isernia to Rome. Which seat classes are available or what are the amenities of operators on your coach trip? Below you´ll find answers to your questions.

FAQs for Isernia to Rome bus

How much does a Isernia Rome coach trip cost?

This depends on, among other things, the day and travel time. The cheapest ticket for the Isernia Rome bus trip is available from £15 and takes 6h 55m. Compare offers and save money!

How much could I save by comparing buses from Isernia to Rome?

This connection is offered by 1 companies with ticket prices ranging from £15 to £54. Therefore, we suggest booking your ticket as soon as possible to ensure you’ll get the cheapest bus trip to Rome.

How many connections are available for the Isernia Rome route on average every day?

Each day, the bus route from Isernia to Rome is offered by roughly 1 busses. By using our search, you can compare bus schedules and find your ideal trip.

How long does a bus to Rome from Isernia take?

The quickest coach from Isernia to Rome is provided by FlixBus and takes 6h 55m. Coach tickets for this connection cost £20. However, keep in mind that the connection can take longer due to traffic.

What time is the first bus from Isernia to Rome?

The earliest bus to Rome departs from Isernia at 11:25. In this context, information about departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

What time is the last coach from Isernia to Rome?

The latest bus to Rome departs from Isernia at 15:50. Please note that departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

Which bus companies serve the Isernia Rome route?

Passengers looking to travel from Isernia to Rome can travel with FlixBus. Compare all available bus tickets with our search to book the trip that works best for you.

Is there a direct bus between Isernia and Rome?

You can check all the direct connections between Isernia and Rome by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus.

What can I take with me on the bus to Rome from Isernia?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the bus for the Isernia Rome bus route free of charge. Simply use our search to find a coach that is best suited to your needs for your planned travel date.

What equipment is available for the Isernia Rome bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make travelling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Isernia to Rome on your planned travel date.

Available seat classes which are offered on the bus route Isernia to Rome

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Isernia and to Rome

Here’s an overview of the most popular bus routes to Isernia and to Rome. Simply click on the connection of your choice, and you’ll find all the details about your bus route!