Which bus from Mendoza to Santiago del Estero is the best?
Check the bus schedule for Mendoza to Santiago del Estero. Here is a selection of the cheapest coach trips for the next days from bus operators like Andesmar, San Juan Mar del Plata or 20 de Junio. To see the full timetable for all coaches just use or search and compare.
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| San Juan Mar del Plata | 17h 10m | 10:50 | Mendoza | Bus Station | 04:00 | Santiago del Estero | Central Coach Station | Premium Economy | £54 |
A Bus from San Juan Mar del Plata goes from Bus Station, Mendoza (Argentina) at 06/12/2025 10:50:00 to Central Coach Station, Santiago del Estero (Argentina) arriving at 07/12/2025 04:00:00. 50 Premium Economy ticket for £54 per person are available. Travel duration is 17h 10m
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| Andesmar | 16h 5m | 21:30 | Mendoza | Bus Station | 13:35 | Santiago del Estero | Central Coach Station | Premium Economy | £55 |
A Bus from Andesmar goes from Bus Station, Mendoza (Argentina) at 06/12/2025 21:30:00 to Central Coach Station, Santiago del Estero (Argentina) arriving at 07/12/2025 13:35:00. 50 Premium Economy ticket for £55 per person are available. Travel duration is 16h 5m
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| 20 de Junio | 19h 20m | 20:30 | Mendoza | Bus Station | 15:50 | Santiago del Estero | Central Coach Station | First Class | £75 |
A Bus from 20 de Junio goes from Bus Station, Mendoza (Argentina) at 06/12/2025 20:30:00 to Central Coach Station, Santiago del Estero (Argentina) arriving at 07/12/2025 15:50:00. 50 First Class ticket for £75 per person are available. Travel duration is 19h 20m
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Plataforma 1016h 45m009:00MendozaBus Station19:30Córdoba, CDBus Station0Premium EconomyA Bus from Plataforma 10 goes from Bus Station, Mendoza (Argentina) at 08/12/2025 09:00:00 to Bus Station, Córdoba, CD (Argentina) arriving at 08/12/2025 19:30:00. 50 Premium Economy ticket for £23 per person are available. Travel duration is 10h 30m
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Plataforma 105h 55m019:50Córdoba, CDBus Station01:45Santiago del EsteroCentral Coach Station0Premium EconomyA Bus from Plataforma 10 goes from Bus Station, Córdoba, CD (Argentina) at 08/12/2025 19:50:00 to Central Coach Station, Santiago del Estero (Argentina) arriving at 09/12/2025 01:45:00. 50 Premium Economy ticket for £12 per person are available. Travel duration is 5h 55m
Waiting Time 0h 20m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| San Juan Mar del Plata | 17h 10m | 10:50 | Mendoza | Bus Station | 04:00 | Santiago del Estero | Central Coach Station | Premium Economy | £54 |
A Bus from San Juan Mar del Plata goes from Bus Station, Mendoza (Argentina) at 07/12/2025 10:50:00 to Central Coach Station, Santiago del Estero (Argentina) arriving at 08/12/2025 04:00:00. 50 Premium Economy ticket for £54 per person are available. Travel duration is 17h 10m
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| Andesmar | 16h 5m | 21:30 | Mendoza | Bus Station | 13:35 | Santiago del Estero | Central Coach Station | Premium Economy | £55 |
A Bus from Andesmar goes from Bus Station, Mendoza (Argentina) at 07/12/2025 21:30:00 to Central Coach Station, Santiago del Estero (Argentina) arriving at 08/12/2025 13:35:00. 50 Premium Economy ticket for £55 per person are available. Travel duration is 16h 5m
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| 20 de Junio | 19h 20m | 20:30 | Mendoza | Bus Station | 15:50 | Santiago del Estero | Central Coach Station | First Class | £75 |
A Bus from 20 de Junio goes from Bus Station, Mendoza (Argentina) at 07/12/2025 20:30:00 to Central Coach Station, Santiago del Estero (Argentina) arriving at 08/12/2025 15:50:00. 50 First Class ticket for £75 per person are available. Travel duration is 19h 20m
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Plataforma 1016h 45m009:00MendozaBus Station19:30Córdoba, CDBus Station0Premium EconomyA Bus from Plataforma 10 goes from Bus Station, Mendoza (Argentina) at 08/12/2025 09:00:00 to Bus Station, Córdoba, CD (Argentina) arriving at 08/12/2025 19:30:00. 50 Premium Economy ticket for £23 per person are available. Travel duration is 10h 30m
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Plataforma 105h 55m019:50Córdoba, CDBus Station01:45Santiago del EsteroCentral Coach Station0Premium EconomyA Bus from Plataforma 10 goes from Bus Station, Córdoba, CD (Argentina) at 08/12/2025 19:50:00 to Central Coach Station, Santiago del Estero (Argentina) arriving at 09/12/2025 01:45:00. 50 Premium Economy ticket for £12 per person are available. Travel duration is 5h 55m
Waiting Time 0h 20m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| San Juan Mar del Plata | 17h 10m | 10:50 | Mendoza | Bus Station | 04:00 | Santiago del Estero | Central Coach Station | Premium Economy | £54 |
A Bus from San Juan Mar del Plata goes from Bus Station, Mendoza (Argentina) at 08/12/2025 10:50:00 to Central Coach Station, Santiago del Estero (Argentina) arriving at 09/12/2025 04:00:00. 50 Premium Economy ticket for £54 per person are available. Travel duration is 17h 10m
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| Andesmar | 16h 5m | 21:30 | Mendoza | Bus Station | 13:35 | Santiago del Estero | Central Coach Station | Premium Economy | £55 |
A Bus from Andesmar goes from Bus Station, Mendoza (Argentina) at 08/12/2025 21:30:00 to Central Coach Station, Santiago del Estero (Argentina) arriving at 09/12/2025 13:35:00. 50 Premium Economy ticket for £55 per person are available. Travel duration is 16h 5m
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Plataforma 1021h 40m021:30MendozaBus Station07:35Córdoba, CDBus Station0Premium EconomyA Bus from Plataforma 10 goes from Bus Station, Mendoza (Argentina) at 09/12/2025 21:30:00 to Bus Station, Córdoba, CD (Argentina) arriving at 10/12/2025 07:35:00. 50 Premium Economy ticket for £20 per person are available. Travel duration is 10h 5m
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Voyenbus5h 55m013:15Córdoba, CDBus Station19:10Santiago del EsteroCentral Coach Station0Premium EconomyA Bus from Voyenbus goes from Bus Station, Córdoba, CD (Argentina) at 10/12/2025 13:15:00 to Central Coach Station, Santiago del Estero (Argentina) arriving at 10/12/2025 19:10:00. 50 Premium Economy ticket for £12 per person are available. Travel duration is 5h 55m
Waiting Time 5h 40m -
Best Price Offer: The price for the cheapest coach from Mendoza to Santiago del Estero is £43 on 03/12/2025. Flexible travellers save on ticket prices.
What is the best day and time to travel by bus between Mendoza and Santiago del Estero?
All facts for Mendoza to Santiago del Estero bus at a glance
Compare all coach operators like Andesmar, San Juan Mar del Plata and 20 de Junio that travel daily 7 times by bus from Mendoza to Santiago del Estero in one click. Book your Mendoza to Santiago del Estero bus ticket starting from £43!
| Cheapest Bus | £43 |
| Fastest Bus | 16h 5m |
| Earliest Coach | 10:50 |
| Latest Coach | 21:30 |
| Daily Bus Connections | 7 Ø |
| Distance | 716.8 km |
| Coach Companies | Andesmar, San Juan Mar del Plata and 20 de Junio |
What are the cheapest coach tickets from Mendoza to Santiago del Estero?
Every day, 7 buses from 3 coach companies leave Mendoza for Santiago del Estero. Check the table below to find the cheapest prices for coach tickets for this route, starting from 05/12/2025 and for the following days. Make sure get the cheapest bus ticket!
The cheapest time to travel from Mendoza to Santiago del Estero
How to save money travelling from Mendoza to Santiago del Estero
Book the ticket from Mendoza to Santiago del Estero in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the coach from Mendoza to Santiago del Estero, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Mendoza to Santiago del Estero are also emptier.Check for bus deals and promotions for all bus companies in this route. On CheckMyBus we show special offers directly in the coach trip on our search. Sign-up and check or deals sections and get notifications on our latest travel hacks.
All bus stations and stops in Mendoza and Santiago del Estero
Here is a map with all coach stations in Mendoza and Santiago del Estero. Compare which stop is closest to your destination to save time to find the fastest buses and connections.
Compare the bus with other modes of transport
All you need to know when you travel by bus from Mendoza to Santiago del Estero
FAQs for Mendoza to Santiago del Estero bus
How much does a Mendoza Santiago del Estero coach trip cost?
How much could I save by comparing buses from Mendoza to Santiago del Estero?
How many connections are available for the Mendoza Santiago del Estero route on average every day?
How long does a bus to Santiago del Estero from Mendoza take?
What time is the first bus from Mendoza to Santiago del Estero?
What time is the last coach from Mendoza to Santiago del Estero?
Which bus companies serve the Mendoza Santiago del Estero route?
Is there a direct bus between Mendoza and Santiago del Estero?
What can I take with me on the bus to Santiago del Estero from Mendoza?
What equipment is available for the Mendoza Santiago del Estero bus route?
Available seat classes which are offered on the bus route Mendoza to Santiago del Estero
A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.
Best of the best: you will find the most comfortable accommodation to work or relax during your travel.
More bus routes to Mendoza and to Santiago del Estero
- Bus Routes to Mendoza
- Bus to Mendoza from Bariloche
- Bus from Buenos Aires to Mendoza
- Bus Cipolletti to Mendoza
- Buses Corrientes to Mendoza
- Coach from Eugenio Bustos to Mendoza
- Coach Humahuaca to Mendoza
- La Quiaca to Mendoza coach
- Bus Mar del Plata to Mendoza
- Coaches Potrerillos, MZ to Mendoza
- Resistencia to Mendoza coach
- Coach from Rosario, SF to Mendoza
- Coach Salta to Mendoza
- Bus San Miguel de Tucumán to Mendoza
- Coach from San Salvador de Jujuy, JJ to Mendoza
- Bus to Mendoza from Santiago, RM
- Tunuyán, MZ to Mendoza coach
- Bus Routes to Santiago del Estero
- Coach Belén de Escobar to Santiago del Estero
- Coaches El Talar to Santiago del Estero
- Coach from Florencio Varela to Santiago del Estero
- Bus from Posadas to Santiago del Estero
- Coaches Rosario, SF to Santiago del Estero
- Bus from Salta to Santiago del Estero
- San Fernando del Valle de Catamarca to Santiago del Estero bus
- Bus from San Salvador de Jujuy, JJ to Santiago del Estero

