Which bus from Mendoza to Santiago del Estero is the best?
Check the bus schedule for Mendoza to Santiago del Estero. Here is a selection of the cheapest coach trips for the next days from bus operators like Andesmar or Autotransportes San Juan. To see the full timetable for all coaches just use or search and compare.
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Autotransportes San Juan | 17h 10m | 10:50 | Mendoza | Bus Station | 04:00 | Santiago del Estero | Central Coach Station | Premium Economy | £56 |
A Bus from Autotransportes San Juan goes from Bus Station, Mendoza (Argentina) at 21/03/2026 10:50:00 to Central Coach Station, Santiago del Estero (Argentina) arriving at 22/03/2026 04:00:00. 50 Premium Economy ticket for £56 per person are available. Travel duration is 17h 10m
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| Andesmar | 16h 5m | 21:30 | Mendoza | Bus Station | 13:35 | Santiago del Estero | Central Coach Station | Premium Economy | £57 |
A Bus from Andesmar goes from Bus Station, Mendoza (Argentina) at 21/03/2026 21:30:00 to Central Coach Station, Santiago del Estero (Argentina) arriving at 22/03/2026 13:35:00. 50 Premium Economy ticket for £57 per person are available. Travel duration is 16h 5m
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20 de Junio17h 50m010:00MendozaBus Station01:20San Miguel de TucumánCoach Station0Premium EconomyA Bus from 20 de Junio goes from Bus Station, Mendoza (Argentina) at 23/03/2026 10:00:00 to Coach Station, San Miguel de Tucumán (Argentina) arriving at 24/03/2026 01:20:00. 50 Premium Economy ticket for £34 per person are available. Travel duration is 15h 20m
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Balut2h 10m001:40San Miguel de TucumánCoach Station03:50Santiago del EsteroCentral Coach Station0Premium EconomyA Bus from Balut goes from Coach Station, San Miguel de Tucumán (Argentina) at 24/03/2026 01:40:00 to Central Coach Station, Santiago del Estero (Argentina) arriving at 24/03/2026 03:50:00. 50 Premium Economy ticket for £11 per person are available. Travel duration is 2h 10m
Waiting Time 0h 20m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Autotransportes San Juan | 17h 10m | 10:50 | Mendoza | Bus Station | 04:00 | Santiago del Estero | Central Coach Station | Premium Economy | £56 |
A Bus from Autotransportes San Juan goes from Bus Station, Mendoza (Argentina) at 22/03/2026 10:50:00 to Central Coach Station, Santiago del Estero (Argentina) arriving at 23/03/2026 04:00:00. 50 Premium Economy ticket for £56 per person are available. Travel duration is 17h 10m
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| Andesmar | 16h 5m | 21:30 | Mendoza | Bus Station | 13:35 | Santiago del Estero | Central Coach Station | Premium Economy | £57 |
A Bus from Andesmar goes from Bus Station, Mendoza (Argentina) at 22/03/2026 21:30:00 to Central Coach Station, Santiago del Estero (Argentina) arriving at 23/03/2026 13:35:00. 50 Premium Economy ticket for £57 per person are available. Travel duration is 16h 5m
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20 de Junio20h 25m010:00MendozaBus Station01:20San Miguel de TucumánCoach Station0Premium EconomyA Bus from 20 de Junio goes from Bus Station, Mendoza (Argentina) at 23/03/2026 10:00:00 to Coach Station, San Miguel de Tucumán (Argentina) arriving at 24/03/2026 01:20:00. 50 Premium Economy ticket for £34 per person are available. Travel duration is 15h 20m
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Andesmar2h 35m003:50San Miguel de TucumánCoach Station06:25Santiago del EsteroCentral Coach Station0Premium EconomyA Bus from Andesmar goes from Coach Station, San Miguel de Tucumán (Argentina) at 24/03/2026 03:50:00 to Central Coach Station, Santiago del Estero (Argentina) arriving at 24/03/2026 06:25:00. 50 Premium Economy ticket for £10 per person are available. Travel duration is 2h 35m
Waiting Time 2h 30m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Andesmar | 16h 5m | 21:30 | Mendoza | Bus Station | 13:35 | Santiago del Estero | Central Coach Station | Premium Economy | £57 |
A Bus from Andesmar goes from Bus Station, Mendoza (Argentina) at 23/03/2026 21:30:00 to Central Coach Station, Santiago del Estero (Argentina) arriving at 24/03/2026 13:35:00. 50 Premium Economy ticket for £57 per person are available. Travel duration is 16h 5m
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20 de Junio20h 25m010:00MendozaBus Station01:20San Miguel de TucumánCoach Station0Premium EconomyA Bus from 20 de Junio goes from Bus Station, Mendoza (Argentina) at 23/03/2026 10:00:00 to Coach Station, San Miguel de Tucumán (Argentina) arriving at 24/03/2026 01:20:00. 50 Premium Economy ticket for £34 per person are available. Travel duration is 15h 20m
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Andesmar2h 35m003:50San Miguel de TucumánCoach Station06:25Santiago del EsteroCentral Coach Station0Premium EconomyA Bus from Andesmar goes from Coach Station, San Miguel de Tucumán (Argentina) at 24/03/2026 03:50:00 to Central Coach Station, Santiago del Estero (Argentina) arriving at 24/03/2026 06:25:00. 50 Premium Economy ticket for £10 per person are available. Travel duration is 2h 35m
Waiting Time 2h 30m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Autotransportes San Juan | 17h 10m | 10:50 | Mendoza | Bus Station | 04:00 | Santiago del Estero | Central Coach Station | Premium Economy | £56 |
A Bus from Autotransportes San Juan goes from Bus Station, Mendoza (Argentina) at 24/03/2026 10:50:00 to Central Coach Station, Santiago del Estero (Argentina) arriving at 25/03/2026 04:00:00. 50 Premium Economy ticket for £56 per person are available. Travel duration is 17h 10m
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| Andesmar | 16h 5m | 21:30 | Mendoza | Bus Station | 13:35 | Santiago del Estero | Central Coach Station | Basic | £57 |
A Bus from Andesmar goes from Bus Station, Mendoza (Argentina) at 24/03/2026 21:30:00 to Central Coach Station, Santiago del Estero (Argentina) arriving at 25/03/2026 13:35:00. 50 Basic ticket for £57 per person are available. Travel duration is 16h 5m
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20 de Junio20h 25m010:00MendozaBus Station01:20San Miguel de TucumánCoach Station0Premium EconomyA Bus from 20 de Junio goes from Bus Station, Mendoza (Argentina) at 23/03/2026 10:00:00 to Coach Station, San Miguel de Tucumán (Argentina) arriving at 24/03/2026 01:20:00. 50 Premium Economy ticket for £34 per person are available. Travel duration is 15h 20m
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Andesmar2h 35m003:50San Miguel de TucumánCoach Station06:25Santiago del EsteroCentral Coach Station0Premium EconomyA Bus from Andesmar goes from Coach Station, San Miguel de Tucumán (Argentina) at 24/03/2026 03:50:00 to Central Coach Station, Santiago del Estero (Argentina) arriving at 24/03/2026 06:25:00. 50 Premium Economy ticket for £10 per person are available. Travel duration is 2h 35m
Waiting Time 2h 30m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Autotransportes San Juan | 17h 10m | 10:50 | Mendoza | Bus Station | 04:00 | Santiago del Estero | Central Coach Station | Premium Economy | £56 |
A Bus from Autotransportes San Juan goes from Bus Station, Mendoza (Argentina) at 25/03/2026 10:50:00 to Central Coach Station, Santiago del Estero (Argentina) arriving at 26/03/2026 04:00:00. 50 Premium Economy ticket for £56 per person are available. Travel duration is 17h 10m
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| Andesmar | 16h 5m | 21:30 | Mendoza | Bus Station | 13:35 | Santiago del Estero | Central Coach Station | Premium Economy | £57 |
A Bus from Andesmar goes from Bus Station, Mendoza (Argentina) at 25/03/2026 21:30:00 to Central Coach Station, Santiago del Estero (Argentina) arriving at 26/03/2026 13:35:00. 50 Premium Economy ticket for £57 per person are available. Travel duration is 16h 5m
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20 de Junio17h 50m010:00MendozaBus Station01:20San Miguel de TucumánCoach Station0Premium EconomyA Bus from 20 de Junio goes from Bus Station, Mendoza (Argentina) at 27/03/2026 10:00:00 to Coach Station, San Miguel de Tucumán (Argentina) arriving at 28/03/2026 01:20:00. 50 Premium Economy ticket for £33 per person are available. Travel duration is 15h 20m
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Balut2h 10m001:40San Miguel de TucumánCoach Station03:50Santiago del EsteroCentral Coach Station0Premium EconomyA Bus from Balut goes from Coach Station, San Miguel de Tucumán (Argentina) at 28/03/2026 01:40:00 to Central Coach Station, Santiago del Estero (Argentina) arriving at 28/03/2026 03:50:00. 50 Premium Economy ticket for £11 per person are available. Travel duration is 2h 10m
Waiting Time 0h 20m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Autotransportes San Juan | 17h 10m | 10:50 | Mendoza | Bus Station | 04:00 | Santiago del Estero | Central Coach Station | Premium Economy | £56 |
A Bus from Autotransportes San Juan goes from Bus Station, Mendoza (Argentina) at 26/03/2026 10:50:00 to Central Coach Station, Santiago del Estero (Argentina) arriving at 27/03/2026 04:00:00. 50 Premium Economy ticket for £56 per person are available. Travel duration is 17h 10m
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| Andesmar | 16h 5m | 21:30 | Mendoza | Bus Station | 13:35 | Santiago del Estero | Central Coach Station | Premium Economy | £57 |
A Bus from Andesmar goes from Bus Station, Mendoza (Argentina) at 26/03/2026 21:30:00 to Central Coach Station, Santiago del Estero (Argentina) arriving at 27/03/2026 13:35:00. 50 Premium Economy ticket for £57 per person are available. Travel duration is 16h 5m
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20 de Junio20h 25m010:00MendozaBus Station01:20San Miguel de TucumánCoach Station0Premium EconomyA Bus from 20 de Junio goes from Bus Station, Mendoza (Argentina) at 27/03/2026 10:00:00 to Coach Station, San Miguel de Tucumán (Argentina) arriving at 28/03/2026 01:20:00. 50 Premium Economy ticket for £33 per person are available. Travel duration is 15h 20m
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Andesmar2h 35m003:50San Miguel de TucumánCoach Station06:25Santiago del EsteroCentral Coach Station0Premium EconomyA Bus from Andesmar goes from Coach Station, San Miguel de Tucumán (Argentina) at 28/03/2026 03:50:00 to Central Coach Station, Santiago del Estero (Argentina) arriving at 28/03/2026 06:25:00. 50 Premium Economy ticket for £10 per person are available. Travel duration is 2h 35m
Waiting Time 2h 30m -
Best Price Offer: The price for the cheapest coach from Mendoza to Santiago del Estero is £56 on 21/03/2026. Flexible travellers save on ticket prices.
What is the best day and time to travel by bus between Mendoza and Santiago del Estero?
All facts for Mendoza to Santiago del Estero bus at a glance
Compare all coach operators like Andesmar and Autotransportes San Juan that travel daily 10 times by bus from Mendoza to Santiago del Estero in one click. Book your Mendoza to Santiago del Estero bus ticket starting from £56!
| Cheapest Bus | £56 |
| Fastest Bus | 16h 5m |
| Earliest Coach | 10:50 |
| Latest Coach | 21:30 |
| Daily Bus Connections | 10 Ø |
| Distance | 716.8 km |
| Coach Companies | Andesmar and Autotransportes San Juan |
What are the cheapest coach tickets from Mendoza to Santiago del Estero?
Every day, 10 buses from 2 coach companies leave Mendoza for Santiago del Estero. Check the table below to find the cheapest prices for coach tickets for this route, starting from 21/03/2026 and for the following days. Make sure get the cheapest bus ticket!
The cheapest time to travel from Mendoza to Santiago del Estero
How to save money travelling from Mendoza to Santiago del Estero
Book the ticket from Mendoza to Santiago del Estero in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the coach from Mendoza to Santiago del Estero, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Mendoza to Santiago del Estero are also emptier.Check for bus deals and promotions for all bus companies in this route. On CheckMyBus we show special offers directly in the coach trip on our search. Sign-up and check or deals sections and get notifications on our latest travel hacks.
All bus stations and stops in Mendoza and Santiago del Estero
Here is a map with all coach stations in Mendoza and Santiago del Estero. Compare which stop is closest to your destination to save time to find the fastest buses and connections.
Compare the bus with other modes of transport
All you need to know when you travel by bus from Mendoza to Santiago del Estero
FAQs for Mendoza to Santiago del Estero bus
How much does a Mendoza Santiago del Estero coach trip cost?
How much could I save by comparing buses from Mendoza to Santiago del Estero?
How many connections are available for the Mendoza Santiago del Estero route on average every day?
How long does a bus to Santiago del Estero from Mendoza take?
What time is the first bus from Mendoza to Santiago del Estero?
What time is the last coach from Mendoza to Santiago del Estero?
Which bus companies serve the Mendoza Santiago del Estero route?
Is there a direct bus between Mendoza and Santiago del Estero?
What can I take with me on the bus to Santiago del Estero from Mendoza?
What equipment is available for the Mendoza Santiago del Estero bus route?
How does CheckMyBus find the best coach deals from Mendoza to Santiago del Estero?
How does CheckMyBus technology work for trips from Mendoza to Santiago del Estero?
Available seat classes which are offered on the bus route Mendoza to Santiago del Estero
Name referring to the typical seat you will find with companies that don’t distinguish between different classes.
A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.
More bus routes to Mendoza and to Santiago del Estero
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- Bus Routes to Santiago del Estero
- Coaches El Talar to Santiago del Estero
- Coach from Florencio Varela to Santiago del Estero
- Bus from Posadas, AR to Santiago del Estero
- Coaches Rosario, SF to Santiago del Estero
- Bus from Salta to Santiago del Estero
- San Fernando del Valle de Catamarca to Santiago del Estero bus
- Coach to Santiago del Estero from Termas de Río Hondo
