Which bus from Manchester to Southampton is the best?
Check the bus schedule for Manchester to Southampton. Here is a selection of the cheapest coach trips for the next days from bus operators like FlixBus. To see the full timetable for all coaches just use or search and compare.
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 9h 30m | 13:40 | Manchester | Shudehill Interchange | 23:10 | Southampton | University | Economy | £40 |
A Bus from FlixBus goes from Shudehill Interchange, Manchester (United Kingdom) at 20/03/2026 13:40:00 to University, Southampton (United Kingdom) arriving at 20/03/2026 23:10:00. 50 Economy ticket for £40 per person are available. Travel duration is 9h 30m
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| FlixBus | 9h 45m | 13:40 | Manchester | Shudehill Interchange | 23:25 | Southampton | Coach Station | Economy | £40 |
A Bus from FlixBus goes from Shudehill Interchange, Manchester (United Kingdom) at 20/03/2026 13:40:00 to Coach Station, Southampton (United Kingdom) arriving at 20/03/2026 23:25:00. 50 Economy ticket for £40 per person are available. Travel duration is 9h 45m
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FlixBus8h 55m014:30ManchesterShudehill Interchange17:00BirminghamGreat Charles St Queensway0EconomyA Bus from FlixBus goes from Shudehill Interchange, Manchester (United Kingdom) at 21/03/2026 14:30:00 to Great Charles St Queensway, Birmingham (United Kingdom) arriving at 21/03/2026 17:00:00. 50 Economy ticket for £8 per person are available. Travel duration is 2h 30m
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FlixBus5h 35m017:50BirminghamGreat Charles St Queensway23:25SouthamptonCoach Station0EconomyA Bus from FlixBus goes from Great Charles St Queensway, Birmingham (United Kingdom) at 21/03/2026 17:50:00 to Coach Station, Southampton (United Kingdom) arriving at 21/03/2026 23:25:00. 50 Economy ticket for £19 per person are available. Travel duration is 5h 35m
Waiting Time 0h 50m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 8h 35m | 04:50 | Manchester | Shudehill Interchange | 13:25 | Southampton | University | Economy | £37 |
A Bus from FlixBus goes from Shudehill Interchange, Manchester (United Kingdom) at 21/03/2026 04:50:00 to University, Southampton (United Kingdom) arriving at 21/03/2026 13:25:00. 50 Economy ticket for £37 per person are available. Travel duration is 8h 35m
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| FlixBus | 8h 0m | 15:10 | Manchester | Shudehill Interchange | 23:10 | Southampton | University | Economy | £37 |
A Bus from FlixBus goes from Shudehill Interchange, Manchester (United Kingdom) at 21/03/2026 15:10:00 to University, Southampton (United Kingdom) arriving at 21/03/2026 23:10:00. 50 Economy ticket for £37 per person are available. Travel duration is 8h 0m
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| FlixBus | 8h 50m | 04:50 | Manchester | Shudehill Interchange | 13:40 | Southampton | Coach Station | Economy | £37 |
A Bus from FlixBus goes from Shudehill Interchange, Manchester (United Kingdom) at 21/03/2026 04:50:00 to Coach Station, Southampton (United Kingdom) arriving at 21/03/2026 13:40:00. 50 Economy ticket for £37 per person are available. Travel duration is 8h 50m
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| FlixBus | 8h 15m | 15:10 | Manchester | Shudehill Interchange | 23:25 | Southampton | Coach Station | Economy | £37 |
A Bus from FlixBus goes from Shudehill Interchange, Manchester (United Kingdom) at 21/03/2026 15:10:00 to Coach Station, Southampton (United Kingdom) arriving at 21/03/2026 23:25:00. 50 Economy ticket for £37 per person are available. Travel duration is 8h 15m
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| FlixBus | 9h 0m | 08:30 | Manchester | Shudehill Interchange | 17:30 | Southampton | University | Economy | £38 |
A Bus from FlixBus goes from Shudehill Interchange, Manchester (United Kingdom) at 21/03/2026 08:30:00 to University, Southampton (United Kingdom) arriving at 21/03/2026 17:30:00. 50 Economy ticket for £38 per person are available. Travel duration is 9h 0m
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FlixBus10h 35m002:50ManchesterShudehill Interchange04:45BirminghamGreat Charles St Queensway0EconomyA Bus from FlixBus goes from Shudehill Interchange, Manchester (United Kingdom) at 23/03/2026 02:50:00 to Great Charles St Queensway, Birmingham (United Kingdom) arriving at 23/03/2026 04:45:00. 50 Economy ticket for £8 per person are available. Travel duration is 1h 55m
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FlixBus6h 5m007:20BirminghamGreat Charles St Queensway13:25SouthamptonUniversity0EconomyA Bus from FlixBus goes from Great Charles St Queensway, Birmingham (United Kingdom) at 23/03/2026 07:20:00 to University, Southampton (United Kingdom) arriving at 23/03/2026 13:25:00. 50 Economy ticket for £15 per person are available. Travel duration is 6h 5m
Waiting Time 2h 35m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 8h 35m | 04:50 | Manchester | Shudehill Interchange | 13:25 | Southampton | University | Economy | £40 |
A Bus from FlixBus goes from Shudehill Interchange, Manchester (United Kingdom) at 22/03/2026 04:50:00 to University, Southampton (United Kingdom) arriving at 22/03/2026 13:25:00. 50 Economy ticket for £40 per person are available. Travel duration is 8h 35m
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| FlixBus | 9h 0m | 08:30 | Manchester | Shudehill Interchange | 17:30 | Southampton | University | Economy | £40 |
A Bus from FlixBus goes from Shudehill Interchange, Manchester (United Kingdom) at 22/03/2026 08:30:00 to University, Southampton (United Kingdom) arriving at 22/03/2026 17:30:00. 50 Economy ticket for £40 per person are available. Travel duration is 9h 0m
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| FlixBus | 8h 0m | 15:10 | Manchester | Shudehill Interchange | 23:10 | Southampton | University | Economy | £40 |
A Bus from FlixBus goes from Shudehill Interchange, Manchester (United Kingdom) at 22/03/2026 15:10:00 to University, Southampton (United Kingdom) arriving at 22/03/2026 23:10:00. 50 Economy ticket for £40 per person are available. Travel duration is 8h 0m
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| FlixBus | 8h 50m | 04:50 | Manchester | Shudehill Interchange | 13:40 | Southampton | Coach Station | Economy | £40 |
A Bus from FlixBus goes from Shudehill Interchange, Manchester (United Kingdom) at 22/03/2026 04:50:00 to Coach Station, Southampton (United Kingdom) arriving at 22/03/2026 13:40:00. 50 Economy ticket for £40 per person are available. Travel duration is 8h 50m
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| FlixBus | 9h 15m | 08:30 | Manchester | Shudehill Interchange | 17:45 | Southampton | Coach Station | Economy | £40 |
A Bus from FlixBus goes from Shudehill Interchange, Manchester (United Kingdom) at 22/03/2026 08:30:00 to Coach Station, Southampton (United Kingdom) arriving at 22/03/2026 17:45:00. 50 Economy ticket for £40 per person are available. Travel duration is 9h 15m
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FlixBus8h 40m012:10ManchesterShudehill Interchange14:40BirminghamGreat Charles St Queensway0EconomyA Bus from FlixBus goes from Shudehill Interchange, Manchester (United Kingdom) at 23/03/2026 12:10:00 to Great Charles St Queensway, Birmingham (United Kingdom) arriving at 23/03/2026 14:40:00. 50 Economy ticket for £7 per person are available. Travel duration is 2h 30m
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National Express3h 50m017:00BirminghamCoach Station20:50SouthamptonCoach Station0EconomyA Bus from National Express goes from Coach Station, Birmingham (United Kingdom) at 23/03/2026 17:00:00 to Coach Station, Southampton (United Kingdom) arriving at 23/03/2026 20:50:00. 50 Economy ticket for £11 per person are available. Travel duration is 3h 50m
Waiting Time 2h 20m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 8h 35m | 04:50 | Manchester | Shudehill Interchange | 13:25 | Southampton | University | Economy | £35 |
A Bus from FlixBus goes from Shudehill Interchange, Manchester (United Kingdom) at 23/03/2026 04:50:00 to University, Southampton (United Kingdom) arriving at 23/03/2026 13:25:00. 50 Economy ticket for £35 per person are available. Travel duration is 8h 35m
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| FlixBus | 8h 50m | 04:50 | Manchester | Shudehill Interchange | 13:40 | Southampton | Coach Station | Economy | £35 |
A Bus from FlixBus goes from Shudehill Interchange, Manchester (United Kingdom) at 23/03/2026 04:50:00 to Coach Station, Southampton (United Kingdom) arriving at 23/03/2026 13:40:00. 50 Economy ticket for £35 per person are available. Travel duration is 8h 50m
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| FlixBus | 9h 0m | 08:30 | Manchester | Shudehill Interchange | 17:30 | Southampton | University | Economy | £36 |
A Bus from FlixBus goes from Shudehill Interchange, Manchester (United Kingdom) at 23/03/2026 08:30:00 to University, Southampton (United Kingdom) arriving at 23/03/2026 17:30:00. 50 Economy ticket for £36 per person are available. Travel duration is 9h 0m
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| FlixBus | 9h 30m | 13:40 | Manchester | Shudehill Interchange | 23:10 | Southampton | University | Economy | £36 |
A Bus from FlixBus goes from Shudehill Interchange, Manchester (United Kingdom) at 23/03/2026 13:40:00 to University, Southampton (United Kingdom) arriving at 23/03/2026 23:10:00. 50 Economy ticket for £36 per person are available. Travel duration is 9h 30m
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| FlixBus | 9h 15m | 08:30 | Manchester | Shudehill Interchange | 17:45 | Southampton | Coach Station | Economy | £36 |
A Bus from FlixBus goes from Shudehill Interchange, Manchester (United Kingdom) at 23/03/2026 08:30:00 to Coach Station, Southampton (United Kingdom) arriving at 23/03/2026 17:45:00. 50 Economy ticket for £36 per person are available. Travel duration is 9h 15m
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FlixBus8h 40m012:10ManchesterShudehill Interchange14:40BirminghamGreat Charles St Queensway0EconomyA Bus from FlixBus goes from Shudehill Interchange, Manchester (United Kingdom) at 24/03/2026 12:10:00 to Great Charles St Queensway, Birmingham (United Kingdom) arriving at 24/03/2026 14:40:00. 50 Economy ticket for £6 per person are available. Travel duration is 2h 30m
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National Express3h 50m017:00BirminghamCoach Station20:50SouthamptonCoach Station0EconomyA Bus from National Express goes from Coach Station, Birmingham (United Kingdom) at 24/03/2026 17:00:00 to Coach Station, Southampton (United Kingdom) arriving at 24/03/2026 20:50:00. 50 Economy ticket for £9 per person are available. Travel duration is 3h 50m
Waiting Time 2h 20m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 8h 35m | 04:50 | Manchester | Shudehill Interchange | 13:25 | Southampton | University | Economy | £35 |
A Bus from FlixBus goes from Shudehill Interchange, Manchester (United Kingdom) at 24/03/2026 04:50:00 to University, Southampton (United Kingdom) arriving at 24/03/2026 13:25:00. 50 Economy ticket for £35 per person are available. Travel duration is 8h 35m
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| FlixBus | 9h 0m | 08:30 | Manchester | Shudehill Interchange | 17:30 | Southampton | University | Economy | £35 |
A Bus from FlixBus goes from Shudehill Interchange, Manchester (United Kingdom) at 24/03/2026 08:30:00 to University, Southampton (United Kingdom) arriving at 24/03/2026 17:30:00. 50 Economy ticket for £35 per person are available. Travel duration is 9h 0m
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| FlixBus | 8h 50m | 04:50 | Manchester | Shudehill Interchange | 13:40 | Southampton | Coach Station | Economy | £35 |
A Bus from FlixBus goes from Shudehill Interchange, Manchester (United Kingdom) at 24/03/2026 04:50:00 to Coach Station, Southampton (United Kingdom) arriving at 24/03/2026 13:40:00. 50 Economy ticket for £35 per person are available. Travel duration is 8h 50m
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| FlixBus | 9h 15m | 08:30 | Manchester | Shudehill Interchange | 17:45 | Southampton | Coach Station | Economy | £35 |
A Bus from FlixBus goes from Shudehill Interchange, Manchester (United Kingdom) at 24/03/2026 08:30:00 to Coach Station, Southampton (United Kingdom) arriving at 24/03/2026 17:45:00. 50 Economy ticket for £35 per person are available. Travel duration is 9h 15m
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| FlixBus | 9h 30m | 13:40 | Manchester | Shudehill Interchange | 23:10 | Southampton | University | Economy | £36 |
A Bus from FlixBus goes from Shudehill Interchange, Manchester (United Kingdom) at 24/03/2026 13:40:00 to University, Southampton (United Kingdom) arriving at 24/03/2026 23:10:00. 50 Economy ticket for £36 per person are available. Travel duration is 9h 30m
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FlixBus8h 40m012:10ManchesterShudehill Interchange14:40BirminghamGreat Charles St Queensway0EconomyA Bus from FlixBus goes from Shudehill Interchange, Manchester (United Kingdom) at 24/03/2026 12:10:00 to Great Charles St Queensway, Birmingham (United Kingdom) arriving at 24/03/2026 14:40:00. 50 Economy ticket for £6 per person are available. Travel duration is 2h 30m
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National Express3h 50m017:00BirminghamCoach Station20:50SouthamptonCoach Station0EconomyA Bus from National Express goes from Coach Station, Birmingham (United Kingdom) at 24/03/2026 17:00:00 to Coach Station, Southampton (United Kingdom) arriving at 24/03/2026 20:50:00. 50 Economy ticket for £9 per person are available. Travel duration is 3h 50m
Waiting Time 2h 20m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 8h 35m | 04:50 | Manchester | Shudehill Interchange | 13:25 | Southampton | University | Economy | £34 |
A Bus from FlixBus goes from Shudehill Interchange, Manchester (United Kingdom) at 25/03/2026 04:50:00 to University, Southampton (United Kingdom) arriving at 25/03/2026 13:25:00. 50 Economy ticket for £34 per person are available. Travel duration is 8h 35m
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| FlixBus | 8h 50m | 04:50 | Manchester | Shudehill Interchange | 13:40 | Southampton | Coach Station | Economy | £34 |
A Bus from FlixBus goes from Shudehill Interchange, Manchester (United Kingdom) at 25/03/2026 04:50:00 to Coach Station, Southampton (United Kingdom) arriving at 25/03/2026 13:40:00. 50 Economy ticket for £34 per person are available. Travel duration is 8h 50m
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| FlixBus | 9h 0m | 08:30 | Manchester | Shudehill Interchange | 17:30 | Southampton | University | Economy | £35 |
A Bus from FlixBus goes from Shudehill Interchange, Manchester (United Kingdom) at 25/03/2026 08:30:00 to University, Southampton (United Kingdom) arriving at 25/03/2026 17:30:00. 50 Economy ticket for £35 per person are available. Travel duration is 9h 0m
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| FlixBus | 9h 15m | 08:30 | Manchester | Shudehill Interchange | 17:45 | Southampton | Coach Station | Economy | £35 |
A Bus from FlixBus goes from Shudehill Interchange, Manchester (United Kingdom) at 25/03/2026 08:30:00 to Coach Station, Southampton (United Kingdom) arriving at 25/03/2026 17:45:00. 50 Economy ticket for £35 per person are available. Travel duration is 9h 15m
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| FlixBus | 9h 30m | 13:40 | Manchester | Shudehill Interchange | 23:10 | Southampton | University | Economy | £36 |
A Bus from FlixBus goes from Shudehill Interchange, Manchester (United Kingdom) at 25/03/2026 13:40:00 to University, Southampton (United Kingdom) arriving at 25/03/2026 23:10:00. 50 Economy ticket for £36 per person are available. Travel duration is 9h 30m
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FlixBus8h 40m012:10ManchesterShudehill Interchange14:40BirminghamGreat Charles St Queensway0EconomyA Bus from FlixBus goes from Shudehill Interchange, Manchester (United Kingdom) at 24/03/2026 12:10:00 to Great Charles St Queensway, Birmingham (United Kingdom) arriving at 24/03/2026 14:40:00. 50 Economy ticket for £6 per person are available. Travel duration is 2h 30m
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National Express3h 50m017:00BirminghamCoach Station20:50SouthamptonCoach Station0EconomyA Bus from National Express goes from Coach Station, Birmingham (United Kingdom) at 24/03/2026 17:00:00 to Coach Station, Southampton (United Kingdom) arriving at 24/03/2026 20:50:00. 50 Economy ticket for £9 per person are available. Travel duration is 3h 50m
Waiting Time 2h 20m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 8h 35m | 04:50 | Manchester | Shudehill Interchange | 13:25 | Southampton | University | Economy | £35 |
A Bus from FlixBus goes from Shudehill Interchange, Manchester (United Kingdom) at 26/03/2026 04:50:00 to University, Southampton (United Kingdom) arriving at 26/03/2026 13:25:00. 50 Economy ticket for £35 per person are available. Travel duration is 8h 35m
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| FlixBus | 9h 0m | 08:30 | Manchester | Shudehill Interchange | 17:30 | Southampton | University | Economy | £35 |
A Bus from FlixBus goes from Shudehill Interchange, Manchester (United Kingdom) at 26/03/2026 08:30:00 to University, Southampton (United Kingdom) arriving at 26/03/2026 17:30:00. 50 Economy ticket for £35 per person are available. Travel duration is 9h 0m
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| FlixBus | 8h 50m | 04:50 | Manchester | Shudehill Interchange | 13:40 | Southampton | Coach Station | Economy | £35 |
A Bus from FlixBus goes from Shudehill Interchange, Manchester (United Kingdom) at 26/03/2026 04:50:00 to Coach Station, Southampton (United Kingdom) arriving at 26/03/2026 13:40:00. 50 Economy ticket for £35 per person are available. Travel duration is 8h 50m
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| FlixBus | 9h 15m | 08:30 | Manchester | Shudehill Interchange | 17:45 | Southampton | Coach Station | Economy | £35 |
A Bus from FlixBus goes from Shudehill Interchange, Manchester (United Kingdom) at 26/03/2026 08:30:00 to Coach Station, Southampton (United Kingdom) arriving at 26/03/2026 17:45:00. 50 Economy ticket for £35 per person are available. Travel duration is 9h 15m
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| FlixBus | 9h 30m | 13:40 | Manchester | Shudehill Interchange | 23:10 | Southampton | University | Economy | £36 |
A Bus from FlixBus goes from Shudehill Interchange, Manchester (United Kingdom) at 26/03/2026 13:40:00 to University, Southampton (United Kingdom) arriving at 26/03/2026 23:10:00. 50 Economy ticket for £36 per person are available. Travel duration is 9h 30m
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FlixBus8h 40m012:10ManchesterShudehill Interchange14:40BirminghamGreat Charles St Queensway0EconomyA Bus from FlixBus goes from Shudehill Interchange, Manchester (United Kingdom) at 24/03/2026 12:10:00 to Great Charles St Queensway, Birmingham (United Kingdom) arriving at 24/03/2026 14:40:00. 50 Economy ticket for £6 per person are available. Travel duration is 2h 30m
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National Express3h 50m017:00BirminghamCoach Station20:50SouthamptonCoach Station0EconomyA Bus from National Express goes from Coach Station, Birmingham (United Kingdom) at 24/03/2026 17:00:00 to Coach Station, Southampton (United Kingdom) arriving at 24/03/2026 20:50:00. 50 Economy ticket for £9 per person are available. Travel duration is 3h 50m
Waiting Time 2h 20m -
Best Price Offer: The price for the cheapest coach from Manchester to Southampton is £34 on 25/03/2026. Flexible travellers save on ticket prices.
What is the best day and time to travel by bus between Manchester and Southampton?
All facts for Manchester to Southampton bus at a glance
Compare all coach operators like FlixBus that travel daily 5 times by bus from Manchester to Southampton in one click. Book your Manchester to Southampton bus ticket starting from £34!
| Cheapest Bus | £34 |
| Fastest Bus | 8h 0m |
| Earliest Coach | 13:40 |
| Latest Coach | 13:40 |
| Daily Bus Connections | 5 Ø |
| Distance | 291.5 km |
| Coach Companies | FlixBus |
What are the cheapest coach tickets from Manchester to Southampton?
Every day, 5 buses from 1 coach companies leave Manchester for Southampton. Check the table below to find the cheapest prices for coach tickets for this route, starting from 20/03/2026 and for the following days. Make sure get the cheapest bus ticket!
The cheapest time to travel from Manchester to Southampton
How to save money travelling from Manchester to Southampton
Book the ticket from Manchester to Southampton in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the coach from Manchester to Southampton, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Manchester to Southampton are also emptier.Check for bus deals and promotions for all bus companies in this route. On CheckMyBus we show special offers directly in the coach trip on our search. Sign-up and check or deals sections and get notifications on our latest travel hacks.
What are the most popular bus companies from Manchester to Southampton?
FlixBus from Manchester to Southampton
Here you will find the key facts about the FlixBus bus route Manchester to Southampton:
| Cheapest Price | £34 |
| Fastest Coach | 8h 0m |
| Earliest Coach | 13:40 |
| Last Coach | 13:40 |
| Daily Connections | 5 Ø |
| Found on | 20/03/2026 |
All bus stations and stops in Manchester and Southampton
Here is a map with all coach stations in Manchester and Southampton. Compare which stop is closest to your destination to save time to find the fastest buses and connections.
All you need to know when you travel by bus from Manchester to Southampton
FAQs for Manchester to Southampton bus
How much does a Manchester Southampton coach trip cost?
How much could I save by comparing buses from Manchester to Southampton?
How many connections are available for the Manchester Southampton route on average every day?
How long does a bus to Southampton from Manchester take?
What time is the first bus from Manchester to Southampton?
What time is the last coach from Manchester to Southampton?
Which bus companies serve the Manchester Southampton route?
Is there a direct bus between Manchester and Southampton?
What can I take with me on the bus to Southampton from Manchester?
What equipment is available for the Manchester Southampton bus route?
How does CheckMyBus find the best coach deals from Manchester to Southampton?
How does CheckMyBus technology work for trips from Manchester to Southampton?
Available seat classes which are offered on the bus route Manchester to Southampton
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
More bus routes to Manchester and to Southampton
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