Which bus from Brussels to Prague is the best?
Check the bus schedule for Brussels to Prague. Here is a selection of the cheapest coach trips for the next days from bus operators like FlixBus or European Sleeper. To see the full timetable for all coaches just use or search and compare.
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 18h 35m | 22:55 | Brussels | North Station | 17:30 | Prague | Wilsonova Coach Station | Economy | £52 |
A Bus from FlixBus goes from North Station, Brussels (Belgium) at 05/12/2025 22:55:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 06/12/2025 17:30:00. 50 Economy ticket for £52 per person are available. Travel duration is 18h 35m
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| FlixBus | 19h 35m | 22:00 | Brussels | North Station | 17:35 | Prague | Hradčanská | Economy | £52 |
A Bus from FlixBus goes from North Station, Brussels (Belgium) at 05/12/2025 22:00:00 to Hradčanská, Prague (Czech Republic) arriving at 06/12/2025 17:35:00. 50 Economy ticket for £52 per person are available. Travel duration is 19h 35m
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| FlixBus | 13h 35m | 10:30 | Brussels | North Station | 00:05 | Prague | Na Knížecí Station | Economy | £53 |
A Bus from FlixBus goes from North Station, Brussels (Belgium) at 05/12/2025 10:30:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 06/12/2025 00:05:00. 50 Economy ticket for £53 per person are available. Travel duration is 13h 35m
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| European Sleeper | 17h 23m | 19:22 | Brussels | Midi Bus Station | 12:45 | Prague | Wilsonova Coach Station | Economy | £250 |
A Bus from European Sleeper goes from Midi Bus Station, Brussels (Belgium) at 05/12/2025 19:22:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 06/12/2025 12:45:00. 50 Economy ticket for £250 per person are available. Travel duration is 17h 23m
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FlixBus17h 45m006:20BrusselsNorth Station07:30HasseltCentral Station0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 06/12/2025 06:20:00 to Central Station, Hasselt (Belgium) arriving at 06/12/2025 07:30:00. 50 Economy ticket for £6 per person are available. Travel duration is 1h 10m
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FlixBus16h 30m007:35HasseltCentral Station00:05PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Central Station, Hasselt (Belgium) at 06/12/2025 07:35:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 07/12/2025 00:05:00. 50 Economy ticket for £33 per person are available. Travel duration is 16h 30m
Waiting Time 0h 5m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 19h 15m | 16:15 | Brussels | Midi Bus Station | 11:30 | Prague | Wilsonova Coach Station | Economy | £41 |
A Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 06/12/2025 16:15:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 07/12/2025 11:30:00. 50 Economy ticket for £41 per person are available. Travel duration is 19h 15m
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| FlixBus | 15h 15m | 21:25 | Brussels | North Station | 12:40 | Prague | ÚAN Florenc | Economy | £41 |
A Bus from FlixBus goes from North Station, Brussels (Belgium) at 06/12/2025 21:25:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 07/12/2025 12:40:00. 50 Economy ticket for £41 per person are available. Travel duration is 15h 15m
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| FlixBus | 16h 5m | 10:55 | Brussels | North Station | 03:00 | Prague | Wilsonova Coach Station | Economy | £41 |
A Bus from FlixBus goes from North Station, Brussels (Belgium) at 06/12/2025 10:55:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 07/12/2025 03:00:00. 50 Economy ticket for £41 per person are available. Travel duration is 16h 5m
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| FlixBus | 19h 35m | 11:20 | Brussels | North Station | 06:55 | Prague | Wilsonova Coach Station | Economy | £41 |
A Bus from FlixBus goes from North Station, Brussels (Belgium) at 06/12/2025 11:20:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 07/12/2025 06:55:00. 50 Economy ticket for £41 per person are available. Travel duration is 19h 35m
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| FlixBus | 16h 35m | 21:25 | Brussels | North Station | 14:00 | Prague | Wilsonova Coach Station | Economy | £41 |
A Bus from FlixBus goes from North Station, Brussels (Belgium) at 06/12/2025 21:25:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 07/12/2025 14:00:00. 50 Economy ticket for £41 per person are available. Travel duration is 16h 35m
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FlixBus17h 45m006:20BrusselsNorth Station08:25MaastrichtMeerssenerweg0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 08/12/2025 06:20:00 to Meerssenerweg, Maastricht (Netherlands) arriving at 08/12/2025 08:25:00. 50 Economy ticket for £7 per person are available. Travel duration is 2h 5m
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FlixBus15h 35m008:30MaastrichtMeerssenerweg00:05PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Meerssenerweg, Maastricht (Netherlands) at 08/12/2025 08:30:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 09/12/2025 00:05:00. 50 Economy ticket for £30 per person are available. Travel duration is 15h 35m
Waiting Time 0h 5m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 16h 5m | 10:55 | Brussels | North Station | 03:00 | Prague | Wilsonova Coach Station | Economy | £52 |
A Bus from FlixBus goes from North Station, Brussels (Belgium) at 07/12/2025 10:55:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 08/12/2025 03:00:00. 50 Economy ticket for £52 per person are available. Travel duration is 16h 5m
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| FlixBus | 18h 35m | 22:55 | Brussels | North Station | 17:30 | Prague | Wilsonova Coach Station | Economy | £52 |
A Bus from FlixBus goes from North Station, Brussels (Belgium) at 07/12/2025 22:55:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 08/12/2025 17:30:00. 50 Economy ticket for £52 per person are available. Travel duration is 18h 35m
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| FlixBus | 19h 35m | 22:00 | Brussels | North Station | 17:35 | Prague | Hradčanská | Economy | £52 |
A Bus from FlixBus goes from North Station, Brussels (Belgium) at 07/12/2025 22:00:00 to Hradčanská, Prague (Czech Republic) arriving at 08/12/2025 17:35:00. 50 Economy ticket for £52 per person are available. Travel duration is 19h 35m
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| FlixBus | 17h 50m | 01:20 | Brussels | Midi Bus Station | 19:10 | Prague | Na Knížecí Station | Economy | £56 |
A Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 07/12/2025 01:20:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 07/12/2025 19:10:00. 50 Economy ticket for £56 per person are available. Travel duration is 17h 50m
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| FlixBus | 18h 30m | 01:20 | Brussels | Midi Bus Station | 19:50 | Prague | Zličín | Economy | £57 |
A Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 07/12/2025 01:20:00 to Zličín, Prague (Czech Republic) arriving at 07/12/2025 19:50:00. 50 Economy ticket for £57 per person are available. Travel duration is 18h 30m
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FlixBus18h 10m019:00BrusselsNorth Station21:10MaastrichtMeerssenerweg0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 08/12/2025 19:00:00 to Meerssenerweg, Maastricht (Netherlands) arriving at 08/12/2025 21:10:00. 50 Economy ticket for £5 per person are available. Travel duration is 2h 10m
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FlixBus14h 5m023:05MaastrichtMeerssenerweg13:10PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Meerssenerweg, Maastricht (Netherlands) at 08/12/2025 23:05:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 09/12/2025 13:10:00. 50 Economy ticket for £30 per person are available. Travel duration is 14h 5m
Waiting Time 1h 55m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 16h 40m | 16:15 | Brussels | Midi Bus Station | 08:55 | Prague | Na Knížecí Station | Economy | £38 |
A Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 08/12/2025 16:15:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 09/12/2025 08:55:00. 50 Economy ticket for £38 per person are available. Travel duration is 16h 40m
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| FlixBus | 16h 10m | 07:00 | Brussels | North Station | 23:10 | Prague | ÚAN Florenc | Economy | £38 |
A Bus from FlixBus goes from North Station, Brussels (Belgium) at 08/12/2025 07:00:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 08/12/2025 23:10:00. 50 Economy ticket for £38 per person are available. Travel duration is 16h 10m
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| FlixBus | 15h 0m | 15:55 | Brussels | North Station | 06:55 | Prague | ÚAN Florenc | Economy | £38 |
A Bus from FlixBus goes from North Station, Brussels (Belgium) at 08/12/2025 15:55:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 09/12/2025 06:55:00. 50 Economy ticket for £38 per person are available. Travel duration is 15h 0m
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| European Sleeper | 17h 23m | 19:22 | Brussels | Midi Bus Station | 12:45 | Prague | Wilsonova Coach Station | Economy | £233 |
A Bus from European Sleeper goes from Midi Bus Station, Brussels (Belgium) at 08/12/2025 19:22:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 09/12/2025 12:45:00. 50 Economy ticket for £233 per person are available. Travel duration is 17h 23m
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FlixBus21h 0m011:55BrusselsMidi Bus Station14:35MaastrichtMeerssenerweg0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 09/12/2025 11:55:00 to Meerssenerweg, Maastricht (Netherlands) arriving at 09/12/2025 14:35:00. 50 Economy ticket for £5 per person are available. Travel duration is 2h 40m
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FlixBus13h 45m019:10MaastrichtMeerssenerweg08:55PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Meerssenerweg, Maastricht (Netherlands) at 09/12/2025 19:10:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 10/12/2025 08:55:00. 50 Economy ticket for £29 per person are available. Travel duration is 13h 45m
Waiting Time 4h 35m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 16h 40m | 16:15 | Brussels | Midi Bus Station | 08:55 | Prague | Na Knížecí Station | Economy | £34 |
A Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 09/12/2025 16:15:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 10/12/2025 08:55:00. 50 Economy ticket for £34 per person are available. Travel duration is 16h 40m
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| FlixBus | 15h 10m | 17:30 | Brussels | North Station | 08:40 | Prague | ÚAN Florenc | Economy | £34 |
A Bus from FlixBus goes from North Station, Brussels (Belgium) at 09/12/2025 17:30:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 10/12/2025 08:40:00. 50 Economy ticket for £34 per person are available. Travel duration is 15h 10m
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| FlixBus | 18h 35m | 22:55 | Brussels | North Station | 17:30 | Prague | Wilsonova Coach Station | Economy | £34 |
A Bus from FlixBus goes from North Station, Brussels (Belgium) at 09/12/2025 22:55:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 10/12/2025 17:30:00. 50 Economy ticket for £34 per person are available. Travel duration is 18h 35m
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| FlixBus | 15h 25m | 17:30 | Brussels | North Station | 08:55 | Prague | Na Knížecí Station | Economy | £34 |
A Bus from FlixBus goes from North Station, Brussels (Belgium) at 09/12/2025 17:30:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 10/12/2025 08:55:00. 50 Economy ticket for £34 per person are available. Travel duration is 15h 25m
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| FlixBus | 17h 50m | 01:20 | Brussels | Midi Bus Station | 19:10 | Prague | Na Knížecí Station | Economy | £35 |
A Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 09/12/2025 01:20:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 09/12/2025 19:10:00. 50 Economy ticket for £35 per person are available. Travel duration is 17h 50m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 17h 50m | 16:15 | Brussels | Midi Bus Station | 10:05 | Prague | Na Knížecí Station | Economy | £36 |
A Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 10/12/2025 16:15:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 11/12/2025 10:05:00. 50 Economy ticket for £36 per person are available. Travel duration is 17h 50m
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| FlixBus | 19h 15m | 16:15 | Brussels | Midi Bus Station | 11:30 | Prague | Wilsonova Coach Station | Economy | £37 |
A Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 10/12/2025 16:15:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 11/12/2025 11:30:00. 50 Economy ticket for £37 per person are available. Travel duration is 19h 15m
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| FlixBus | 16h 35m | 17:30 | Brussels | North Station | 10:05 | Prague | Na Knížecí Station | Economy | £37 |
A Bus from FlixBus goes from North Station, Brussels (Belgium) at 10/12/2025 17:30:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 11/12/2025 10:05:00. 50 Economy ticket for £37 per person are available. Travel duration is 16h 35m
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| European Sleeper | 16h 33m | 19:22 | Brussels | Midi Bus Station | 11:55 | Prague | Wilsonova Coach Station | Economy | £251 |
A Bus from European Sleeper goes from Midi Bus Station, Brussels (Belgium) at 10/12/2025 19:22:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 11/12/2025 11:55:00. 50 Economy ticket for £251 per person are available. Travel duration is 16h 33m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
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| FlixBus | 20h 50m | 21:25 | Brussels | North Station | 18:15 | Prague | Holesovice | Economy | £39 |
A Bus from FlixBus goes from North Station, Brussels (Belgium) at 11/12/2025 21:25:00 to Holesovice, Prague (Czech Republic) arriving at 12/12/2025 18:15:00. 50 Economy ticket for £39 per person are available. Travel duration is 20h 50m
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| FlixBus | 20h 55m | 06:20 | Brussels | North Station | 03:15 | Prague | Wilsonova Coach Station | Economy | £40 |
A Bus from FlixBus goes from North Station, Brussels (Belgium) at 11/12/2025 06:20:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 12/12/2025 03:15:00. 50 Economy ticket for £40 per person are available. Travel duration is 20h 55m
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| FlixBus | 18h 35m | 09:00 | Brussels | North Station | 03:35 | Prague | ÚAN Florenc | Economy | £40 |
A Bus from FlixBus goes from North Station, Brussels (Belgium) at 11/12/2025 09:00:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 12/12/2025 03:35:00. 50 Economy ticket for £40 per person are available. Travel duration is 18h 35m
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| FlixBus | 18h 10m | 14:30 | Brussels | North Station | 08:40 | Prague | ÚAN Florenc | Economy | £43 |
A Bus from FlixBus goes from North Station, Brussels (Belgium) at 11/12/2025 14:30:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 12/12/2025 08:40:00. 50 Economy ticket for £43 per person are available. Travel duration is 18h 10m
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| FlixBus | 19h 15m | 00:45 | Brussels | Midi Bus Station | 20:00 | Prague | Wilsonova Coach Station | Economy | £45 |
A Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 11/12/2025 00:45:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 11/12/2025 20:00:00. 50 Economy ticket for £45 per person are available. Travel duration is 19h 15m
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FlixBus21h 0m011:55BrusselsMidi Bus Station14:35MaastrichtMeerssenerweg0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 09/12/2025 11:55:00 to Meerssenerweg, Maastricht (Netherlands) arriving at 09/12/2025 14:35:00. 50 Economy ticket for £5 per person are available. Travel duration is 2h 40m
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FlixBus13h 45m019:10MaastrichtMeerssenerweg08:55PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Meerssenerweg, Maastricht (Netherlands) at 09/12/2025 19:10:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 10/12/2025 08:55:00. 50 Economy ticket for £29 per person are available. Travel duration is 13h 45m
Waiting Time 4h 35m -
Best Price Offer: The price for the cheapest coach from Brussels to Prague is £34 on 09/12/2025. Flexible travellers save on ticket prices.
What is the best day and time to travel by bus between Brussels and Prague?
All facts for Brussels to Prague bus at a glance
Compare all coach operators like FlixBus and European Sleeper that travel daily 25 times by bus from Brussels to Prague in one click. Book your Brussels to Prague bus ticket starting from £34!
| Cheapest Bus | £34 |
| Fastest Bus | 13h 35m |
| Earliest Coach | 00:45 |
| Latest Coach | 22:55 |
| Daily Bus Connections | 25 Ø |
| Distance | 718.5 km |
| Coach Companies | FlixBus and European Sleeper |
What are the cheapest coach tickets from Brussels to Prague?
Every day, 25 buses from 2 coach companies leave Brussels for Prague. Check the table below to find the cheapest prices for coach tickets for this route, starting from 05/12/2025 and for the following days. Make sure get the cheapest bus ticket!
The cheapest time to travel from Brussels to Prague
How to save money travelling from Brussels to Prague
Book the ticket from Brussels to Prague in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the coach from Brussels to Prague, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Brussels to Prague are also emptier.Check for bus deals and promotions for all bus companies in this route. On CheckMyBus we show special offers directly in the coach trip on our search. Sign-up and check or deals sections and get notifications on our latest travel hacks.
What are the most popular bus companies from Brussels to Prague?
FlixBus from Brussels to Prague
Here you will find the key facts about the FlixBus bus route Brussels to Prague:
| Cheapest Price | £34 |
| Fastest Coach | 13h 35m |
| Earliest Coach | 00:45 |
| Last Coach | 22:55 |
| Daily Connections | 25 Ø |
| Found on | 04/12/2025 |
All bus stations and stops in Brussels and Prague
Here is a map with all coach stations in Brussels and Prague. Compare which stop is closest to your destination to save time to find the fastest buses and connections.
Compare the bus with other modes of transport
All you need to know when you travel by bus from Brussels to Prague
FAQs for Brussels to Prague bus
How much does a Brussels Prague coach trip cost?
How much could I save by comparing buses from Brussels to Prague?
How many connections are available for the Brussels Prague route on average every day?
How long does a bus to Prague from Brussels take?
What time is the first bus from Brussels to Prague?
What time is the last coach from Brussels to Prague?
Which bus companies serve the Brussels Prague route?
Is there a direct bus between Brussels and Prague?
What can I take with me on the bus to Prague from Brussels?
What equipment is available for the Brussels Prague bus route?
Available seat classes which are offered on the bus route Brussels to Prague
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
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