Which bus from Brussels to Prague is the best?
Check the bus schedule for Brussels to Prague. Here is a selection of the cheapest coach trips for the next days from bus operators like FlixBus or European Sleeper. To see the full timetable for all coaches just use or search and compare.
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 17h 40m | 22:30 | Brussels | Midi Bus Station | 16:10 | Prague | Černý Most | Economy | £42 |
A Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 18/09/2026 22:30:00 to Černý Most, Prague (Czech Republic) arriving at 19/09/2026 16:10:00. 50 Economy ticket for £42 per person are available. Travel duration is 17h 40m
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| FlixBus | 17h 5m | 22:55 | Brussels | North Station | 16:00 | Prague | Wilsonova Coach Station | Economy | £44 |
A Bus from FlixBus goes from North Station, Brussels (Belgium) at 18/09/2026 22:55:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 19/09/2026 16:00:00. 50 Economy ticket for £44 per person are available. Travel duration is 17h 5m
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| FlixBus | 18h 50m | 22:55 | Brussels | North Station | 17:45 | Prague | ÚAN Florenc | Economy | £50 |
A Bus from FlixBus goes from North Station, Brussels (Belgium) at 18/09/2026 22:55:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 19/09/2026 17:45:00. 50 Economy ticket for £50 per person are available. Travel duration is 18h 50m
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| European Sleeper | 15h 29m | 19:22 | Brussels | Midi Bus Station | 10:51 | Prague | Wilsonova Coach Station | Economy | £263 |
A Bus from European Sleeper goes from Midi Bus Station, Brussels (Belgium) at 18/09/2026 19:22:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 19/09/2026 10:51:00. 50 Economy ticket for £263 per person are available. Travel duration is 15h 29m
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FlixBus19h 0m019:00BrusselsNorth Station21:10MaastrichtMeerssenerweg0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 19/09/2026 19:00:00 to Meerssenerweg, Maastricht (Netherlands) arriving at 19/09/2026 21:10:00. 50 Economy ticket for £8 per person are available. Travel duration is 2h 10m
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FlixBus14h 50m023:10MaastrichtMeerssenerweg14:00PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Meerssenerweg, Maastricht (Netherlands) at 19/09/2026 23:10:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 20/09/2026 14:00:00. 50 Economy ticket for £23 per person are available. Travel duration is 14h 50m
Waiting Time 2h 0m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 18h 40m | 01:20 | Brussels | Midi Bus Station | 20:00 | Prague | Hradčanská | Economy | £30 |
A Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 19/09/2026 01:20:00 to Hradčanská, Prague (Czech Republic) arriving at 19/09/2026 20:00:00. 50 Economy ticket for £30 per person are available. Travel duration is 18h 40m
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| FlixBus | 17h 50m | 01:20 | Brussels | Midi Bus Station | 19:10 | Prague | Na Knížecí Station | Economy | £30 |
A Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 19/09/2026 01:20:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 19/09/2026 19:10:00. 50 Economy ticket for £30 per person are available. Travel duration is 17h 50m
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| FlixBus | 15h 55m | 07:00 | Brussels | North Station | 22:55 | Prague | Na Knížecí Station | Economy | £30 |
A Bus from FlixBus goes from North Station, Brussels (Belgium) at 19/09/2026 07:00:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 19/09/2026 22:55:00. 50 Economy ticket for £30 per person are available. Travel duration is 15h 55m
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| FlixBus | 15h 10m | 21:30 | Brussels | North Station | 12:40 | Prague | ÚAN Florenc | Economy | £30 |
A Bus from FlixBus goes from North Station, Brussels (Belgium) at 19/09/2026 21:30:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 20/09/2026 12:40:00. 50 Economy ticket for £30 per person are available. Travel duration is 15h 10m
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| FlixBus | 15h 55m | 10:55 | Brussels | North Station | 02:50 | Prague | Wilsonova Coach Station | Economy | £30 |
A Bus from FlixBus goes from North Station, Brussels (Belgium) at 19/09/2026 10:55:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 20/09/2026 02:50:00. 50 Economy ticket for £30 per person are available. Travel duration is 15h 55m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 15h 10m | 21:30 | Brussels | North Station | 12:40 | Prague | ÚAN Florenc | Economy | £41 |
A Bus from FlixBus goes from North Station, Brussels (Belgium) at 20/09/2026 21:30:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 21/09/2026 12:40:00. 50 Economy ticket for £41 per person are available. Travel duration is 15h 10m
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| FlixBus | 18h 40m | 22:55 | Brussels | North Station | 17:35 | Prague | Hradčanská | Economy | £41 |
A Bus from FlixBus goes from North Station, Brussels (Belgium) at 20/09/2026 22:55:00 to Hradčanská, Prague (Czech Republic) arriving at 21/09/2026 17:35:00. 50 Economy ticket for £41 per person are available. Travel duration is 18h 40m
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| FlixBus | 19h 5m | 22:30 | Brussels | Midi Bus Station | 17:35 | Prague | Hradčanská | Economy | £45 |
A Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 20/09/2026 22:30:00 to Hradčanská, Prague (Czech Republic) arriving at 21/09/2026 17:35:00. 50 Economy ticket for £45 per person are available. Travel duration is 19h 5m
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| FlixBus | 16h 30m | 21:30 | Brussels | North Station | 14:00 | Prague | Wilsonova Coach Station | Economy | £45 |
A Bus from FlixBus goes from North Station, Brussels (Belgium) at 20/09/2026 21:30:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 21/09/2026 14:00:00. 50 Economy ticket for £45 per person are available. Travel duration is 16h 30m
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| FlixBus | 18h 40m | 21:30 | Brussels | North Station | 16:10 | Prague | Černý Most | Economy | £45 |
A Bus from FlixBus goes from North Station, Brussels (Belgium) at 20/09/2026 21:30:00 to Černý Most, Prague (Czech Republic) arriving at 21/09/2026 16:10:00. 50 Economy ticket for £45 per person are available. Travel duration is 18h 40m
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FlixBus21h 10m019:00BrusselsNorth Station21:10MaastrichtMeerssenerweg0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 21/09/2026 19:00:00 to Meerssenerweg, Maastricht (Netherlands) arriving at 21/09/2026 21:10:00. 50 Economy ticket for £6 per person are available. Travel duration is 2h 10m
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FlixBus14h 55m001:15MaastrichtMeerssenerweg16:10PragueČerný Most0EconomyA Bus from FlixBus goes from Meerssenerweg, Maastricht (Netherlands) at 22/09/2026 01:15:00 to Černý Most, Prague (Czech Republic) arriving at 22/09/2026 16:10:00. 50 Economy ticket for £16 per person are available. Travel duration is 14h 55m
Waiting Time 4h 5m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 16h 40m | 16:15 | Brussels | Midi Bus Station | 08:55 | Prague | Na Knížecí Station | Economy | £23 |
A Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 21/09/2026 16:15:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 22/09/2026 08:55:00. 50 Economy ticket for £23 per person are available. Travel duration is 16h 40m
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| FlixBus | 15h 5m | 06:05 | Brussels | North Station | 21:10 | Prague | Na Knížecí Station | Economy | £23 |
A Bus from FlixBus goes from North Station, Brussels (Belgium) at 21/09/2026 06:05:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 21/09/2026 21:10:00. 50 Economy ticket for £23 per person are available. Travel duration is 15h 5m
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| FlixBus | 17h 0m | 15:55 | Brussels | North Station | 08:55 | Prague | Na Knížecí Station | Economy | £23 |
A Bus from FlixBus goes from North Station, Brussels (Belgium) at 21/09/2026 15:55:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 22/09/2026 08:55:00. 50 Economy ticket for £23 per person are available. Travel duration is 17h 0m
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| European Sleeper | 15h 29m | 19:22 | Brussels | Midi Bus Station | 10:51 | Prague | Wilsonova Coach Station | Economy | £210 |
A Bus from European Sleeper goes from Midi Bus Station, Brussels (Belgium) at 21/09/2026 19:22:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 22/09/2026 10:51:00. 50 Economy ticket for £210 per person are available. Travel duration is 15h 29m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 19h 5m | 22:30 | Brussels | Midi Bus Station | 17:35 | Prague | Hradčanská | Economy | £18 |
A Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 22/09/2026 22:30:00 to Hradčanská, Prague (Czech Republic) arriving at 23/09/2026 17:35:00. 50 Economy ticket for £18 per person are available. Travel duration is 19h 5m
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| FlixBus | 17h 50m | 01:20 | Brussels | Midi Bus Station | 19:10 | Prague | ÚAN Florenc | Economy | £18 |
A Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 22/09/2026 01:20:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 22/09/2026 19:10:00. 50 Economy ticket for £18 per person are available. Travel duration is 17h 50m
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| FlixBus | 16h 40m | 16:15 | Brussels | Midi Bus Station | 08:55 | Prague | Na Knížecí Station | Economy | £18 |
A Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 22/09/2026 16:15:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 23/09/2026 08:55:00. 50 Economy ticket for £18 per person are available. Travel duration is 16h 40m
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| FlixBus | 19h 5m | 17:40 | Brussels | Midi Bus Station | 12:45 | Prague | Na Knížecí Station | Economy | £18 |
A Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 22/09/2026 17:40:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 23/09/2026 12:45:00. 50 Economy ticket for £18 per person are available. Travel duration is 19h 5m
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| FlixBus | 17h 0m | 15:55 | Brussels | North Station | 08:55 | Prague | Na Knížecí Station | Economy | £18 |
A Bus from FlixBus goes from North Station, Brussels (Belgium) at 22/09/2026 15:55:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 23/09/2026 08:55:00. 50 Economy ticket for £18 per person are available. Travel duration is 17h 0m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 17h 25m | 16:40 | Brussels | Midi Bus Station | 10:05 | Prague | Na Knížecí Station | Economy | £19 |
A Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 23/09/2026 16:40:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 24/09/2026 10:05:00. 50 Economy ticket for £19 per person are available. Travel duration is 17h 25m
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| FlixBus | 19h 5m | 22:30 | Brussels | Midi Bus Station | 17:35 | Prague | Hradčanská | Economy | £19 |
A Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 23/09/2026 22:30:00 to Hradčanská, Prague (Czech Republic) arriving at 24/09/2026 17:35:00. 50 Economy ticket for £19 per person are available. Travel duration is 19h 5m
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| FlixBus | 18h 15m | 15:55 | Brussels | Midi Bus Station | 10:10 | Prague | ÚAN Florenc | Economy | £19 |
A Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 23/09/2026 15:55:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 24/09/2026 10:10:00. 50 Economy ticket for £19 per person are available. Travel duration is 18h 15m
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| European Sleeper | 15h 29m | 19:22 | Brussels | Midi Bus Station | 10:51 | Prague | Wilsonova Coach Station | Economy | £228 |
A Bus from European Sleeper goes from Midi Bus Station, Brussels (Belgium) at 23/09/2026 19:22:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 24/09/2026 10:51:00. 50 Economy ticket for £228 per person are available. Travel duration is 15h 29m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
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| FlixBus | 17h 50m | 01:20 | Brussels | Midi Bus Station | 19:10 | Prague | Na Knížecí Station | Economy | £28 |
A Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 24/09/2026 01:20:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 24/09/2026 19:10:00. 50 Economy ticket for £28 per person are available. Travel duration is 17h 50m
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| FlixBus | 16h 35m | 06:20 | Brussels | North Station | 22:55 | Prague | Na Knížecí Station | Economy | £29 |
A Bus from FlixBus goes from North Station, Brussels (Belgium) at 24/09/2026 06:20:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 24/09/2026 22:55:00. 50 Economy ticket for £29 per person are available. Travel duration is 16h 35m
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| FlixBus | 15h 55m | 10:55 | Brussels | North Station | 02:50 | Prague | Wilsonova Coach Station | Economy | £29 |
A Bus from FlixBus goes from North Station, Brussels (Belgium) at 24/09/2026 10:55:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 25/09/2026 02:50:00. 50 Economy ticket for £29 per person are available. Travel duration is 15h 55m
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| FlixBus | 16h 40m | 16:15 | Brussels | Midi Bus Station | 08:55 | Prague | Na Knížecí Station | Economy | £30 |
A Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 24/09/2026 16:15:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 25/09/2026 08:55:00. 50 Economy ticket for £30 per person are available. Travel duration is 16h 40m
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| FlixBus | 18h 40m | 01:20 | Brussels | Midi Bus Station | 20:00 | Prague | Hradčanská | Economy | £30 |
A Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 24/09/2026 01:20:00 to Hradčanská, Prague (Czech Republic) arriving at 24/09/2026 20:00:00. 50 Economy ticket for £30 per person are available. Travel duration is 18h 40m
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FlixBus21h 10m019:00BrusselsNorth Station21:10MaastrichtMeerssenerweg0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 21/09/2026 19:00:00 to Meerssenerweg, Maastricht (Netherlands) arriving at 21/09/2026 21:10:00. 50 Economy ticket for £6 per person are available. Travel duration is 2h 10m
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FlixBus14h 55m001:15MaastrichtMeerssenerweg16:10PragueČerný Most0EconomyA Bus from FlixBus goes from Meerssenerweg, Maastricht (Netherlands) at 22/09/2026 01:15:00 to Černý Most, Prague (Czech Republic) arriving at 22/09/2026 16:10:00. 50 Economy ticket for £16 per person are available. Travel duration is 14h 55m
Waiting Time 4h 5m -
Best Price Offer: The price for the cheapest coach from Brussels to Prague is £18 on 22/09/2026. Flexible travellers save on ticket prices.
What is the best day and time to travel by bus between Brussels and Prague?
All facts for Brussels to Prague bus at a glance
Compare all coach operators like FlixBus and European Sleeper that travel daily 32 times by bus from Brussels to Prague in one click. Book your Brussels to Prague bus ticket starting from £18!
| Cheapest Bus | £18 |
| Fastest Bus | 13h 10m |
| Earliest Coach | 01:20 |
| Latest Coach | 22:55 |
| Daily Bus Connections | 32 Ø |
| Distance | 718.5 km |
| Coach Companies | FlixBus and European Sleeper |
What are the cheapest coach tickets from Brussels to Prague?
Every day, 32 buses from 2 coach companies leave Brussels for Prague. Check the table below to find the cheapest prices for coach tickets for this route, starting from 18/09/2026 and for the following days. Make sure get the cheapest bus ticket!
The cheapest time to travel from Brussels to Prague
How to save money travelling from Brussels to Prague
Book the ticket from Brussels to Prague in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the coach from Brussels to Prague, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Brussels to Prague are also emptier.Check for bus deals and promotions for all bus companies in this route. On CheckMyBus we show special offers directly in the coach trip on our search. Sign-up and check or deals sections and get notifications on our latest travel hacks.
All bus stations and stops in Brussels and Prague
Here is a map with all coach stations in Brussels and Prague. Compare which stop is closest to your destination to save time to find the fastest buses and connections.
All you need to know when you travel by bus from Brussels to Prague
FAQs for Brussels to Prague bus
How much does a Brussels Prague coach trip cost?
How much could I save by comparing buses from Brussels to Prague?
How many connections are available for the Brussels Prague route on average every day?
How long does a bus to Prague from Brussels take?
What time is the first bus from Brussels to Prague?
What time is the last coach from Brussels to Prague?
Which bus companies serve the Brussels Prague route?
Is there a direct bus between Brussels and Prague?
What can I take with me on the bus to Prague from Brussels?
What equipment is available for the Brussels Prague bus route?
How does CheckMyBus find the best coach deals from Brussels to Prague?
How does CheckMyBus technology work for trips from Brussels to Prague?
Available seat classes which are offered on the bus route Brussels to Prague
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
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