What is the best way to travel from St. Louis, MO to Mexico City?
Looking for a trip? Check and compare all the available Flights and Buses to Mexico City from St. Louis, MO. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 2 available companies to find your perfect trip!
What is the cheapest way to reach Mexico City from St. Louis, MO?
You can reach Mexico City with just £154 by taking a Bus from Greyhound US, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
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Greyhound US54h 0m016:30St. Louis, MOGateway Station22:30Mexico CitySan Pedro Santa Clara Coach Stop0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 07/03/2026 16:30:00 to San Pedro Santa Clara Coach Stop, Mexico City (Mexico) arriving at 09/03/2026 22:30:00. 50 Economy ticket for £154 per person are available. Travel duration is 54h 0m
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Greyhound US53h 35m016:30St. Louis, MOGateway Station22:05Mexico CityFórum Buenavista0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 07/03/2026 16:30:00 to Fórum Buenavista, Mexico City (Mexico) arriving at 09/03/2026 22:05:00. 50 Economy ticket for £154 per person are available. Travel duration is 53h 35m
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FlixBus45h 20m016:00St. Louis, MOGateway Station13:20Mexico CitySan Pedro Santa Clara Coach Stop0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 07/03/2026 16:00:00 to San Pedro Santa Clara Coach Stop, Mexico City (Mexico) arriving at 09/03/2026 13:20:00. 50 Economy ticket for £154 per person are available. Travel duration is 45h 20m
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FlixBus44h 55m016:00St. Louis, MOGateway Station12:55Mexico CityFórum Buenavista0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 07/03/2026 16:00:00 to Fórum Buenavista, Mexico City (Mexico) arriving at 09/03/2026 12:55:00. 50 Economy ticket for £154 per person are available. Travel duration is 44h 55m
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Greyhound US45h 55m001:20St. Louis, MOGateway Station23:15Mexico CitySan Pedro Santa Clara Coach Stop0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 07/03/2026 01:20:00 to San Pedro Santa Clara Coach Stop, Mexico City (Mexico) arriving at 08/03/2026 23:15:00. 50 Economy ticket for £157 per person are available. Travel duration is 45h 55m
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Frontier Airlines11h 15m006:00St. Louis Lambert AirportSt. Louis Lambert Airport17:15Mexico City AirportMexico City Airport - T10EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 07/03/2026 06:00:00 to Mexico City Airport - T1, Mexico City Airport (Mexico) arriving at 07/03/2026 17:15:00. 50 Economy ticket for £206 per person are available. Travel duration is 11h 15m
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Frontier Airlines16h 33m007:47St. Louis Lambert AirportSt. Louis Lambert Airport00:20Felipe Ángeles AirportFelipe Ángeles Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 07/03/2026 07:47:00 to Felipe Ángeles Airport, Felipe Ángeles Airport (Mexico) arriving at 08/03/2026 00:20:00. 50 Economy ticket for £240 per person are available. Travel duration is 16h 33m
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Alaska Airlines7h 50m007:00St. Louis Lambert AirportSt. Louis Lambert Airport14:50Mexico City AirportMexico City Airport - T10EconomyA Flight from Alaska Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 07/03/2026 07:00:00 to Mexico City Airport - T1, Mexico City Airport (Mexico) arriving at 07/03/2026 14:50:00. 50 Economy ticket for £248 per person are available. Travel duration is 7h 50m
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Frontier Airlines39h 33m020:12St. Louis Lambert AirportSt. Louis Lambert Airport11:45Felipe Ángeles AirportFelipe Ángeles Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 07/03/2026 20:12:00 to Felipe Ángeles Airport, Felipe Ángeles Airport (Mexico) arriving at 09/03/2026 11:45:00. 50 Economy ticket for £254 per person are available. Travel duration is 39h 33m
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Frontier Airlines35h 18m020:12St. Louis Lambert AirportSt. Louis Lambert Airport07:30Felipe Ángeles AirportFelipe Ángeles Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 07/03/2026 20:12:00 to Felipe Ángeles Airport, Felipe Ángeles Airport (Mexico) arriving at 09/03/2026 07:30:00. 50 Economy ticket for £254 per person are available. Travel duration is 35h 18m
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Delta Air Lines12h 52m007:10St. Louis Lambert AirportSt. Louis Lambert Airport20:02Felipe Ángeles AirportFelipe Ángeles Airport0EconomyA Flight from Delta Air Lines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 07/03/2026 07:10:00 to Felipe Ángeles Airport, Felipe Ángeles Airport (Mexico) arriving at 07/03/2026 20:02:00. 50 Economy ticket for £306 per person are available. Travel duration is 12h 52m
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What are the fastest trips from St. Louis, MO to Mexico City?
You can get to Mexico City from St. Louis, MO in just 7h 50m with a Flight from Alaska Airlines. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
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Alaska Airlines7h 50m007:00St. Louis Lambert AirportSt. Louis Lambert Airport14:50Mexico City AirportMexico City Airport - T10EconomyA Flight from Alaska Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 07/03/2026 07:00:00 to Mexico City Airport - T1, Mexico City Airport (Mexico) arriving at 07/03/2026 14:50:00. 50 Economy ticket for £248 per person are available. Travel duration is 7h 50m
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United Airlines8h 35m005:00St. Louis Lambert AirportSt. Louis Lambert Airport13:35Mexico City AirportMexico City Airport - T10EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 07/03/2026 05:00:00 to Mexico City Airport - T1, Mexico City Airport (Mexico) arriving at 07/03/2026 13:35:00. 50 Economy ticket for £346 per person are available. Travel duration is 8h 35m
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Air Canada8h 45m016:05St. Louis Lambert AirportSt. Louis Lambert Airport00:50Mexico City AirportMexico City Airport - T10EconomyA Flight from Air Canada goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 07/03/2026 16:05:00 to Mexico City Airport - T1, Mexico City Airport (Mexico) arriving at 08/03/2026 00:50:00. 50 Economy ticket for £443 per person are available. Travel duration is 8h 45m
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Frontier Airlines11h 15m006:00St. Louis Lambert AirportSt. Louis Lambert Airport17:15Mexico City AirportMexico City Airport - T10EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 07/03/2026 06:00:00 to Mexico City Airport - T1, Mexico City Airport (Mexico) arriving at 07/03/2026 17:15:00. 50 Economy ticket for £206 per person are available. Travel duration is 11h 15m
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Delta Air Lines11h 50m006:00St. Louis Lambert AirportSt. Louis Lambert Airport17:50Mexico City AirportMexico City Airport - T10EconomyA Flight from Delta Air Lines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 07/03/2026 06:00:00 to Mexico City Airport - T1, Mexico City Airport (Mexico) arriving at 07/03/2026 17:50:00. 50 Economy ticket for £306 per person are available. Travel duration is 11h 50m
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Delta Air Lines12h 52m007:10St. Louis Lambert AirportSt. Louis Lambert Airport20:02Felipe Ángeles AirportFelipe Ángeles Airport0EconomyA Flight from Delta Air Lines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 07/03/2026 07:10:00 to Felipe Ángeles Airport, Felipe Ángeles Airport (Mexico) arriving at 07/03/2026 20:02:00. 50 Economy ticket for £306 per person are available. Travel duration is 12h 52m
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FlixBus44h 55m016:00St. Louis, MOGateway Station12:55Mexico CityFórum Buenavista0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 07/03/2026 16:00:00 to Fórum Buenavista, Mexico City (Mexico) arriving at 09/03/2026 12:55:00. 50 Economy ticket for £154 per person are available. Travel duration is 44h 55m
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FlixBus45h 20m016:00St. Louis, MOGateway Station13:20Mexico CitySan Pedro Santa Clara Coach Stop0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 07/03/2026 16:00:00 to San Pedro Santa Clara Coach Stop, Mexico City (Mexico) arriving at 09/03/2026 13:20:00. 50 Economy ticket for £154 per person are available. Travel duration is 45h 20m
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Greyhound US45h 55m001:20St. Louis, MOGateway Station23:15Mexico CitySan Pedro Santa Clara Coach Stop0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 07/03/2026 01:20:00 to San Pedro Santa Clara Coach Stop, Mexico City (Mexico) arriving at 08/03/2026 23:15:00. 50 Economy ticket for £157 per person are available. Travel duration is 45h 55m
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Greyhound US53h 35m016:30St. Louis, MOGateway Station22:05Mexico CityFórum Buenavista0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 07/03/2026 16:30:00 to Fórum Buenavista, Mexico City (Mexico) arriving at 09/03/2026 22:05:00. 50 Economy ticket for £154 per person are available. Travel duration is 53h 35m
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Greyhound US54h 0m016:30St. Louis, MOGateway Station22:30Mexico CitySan Pedro Santa Clara Coach Stop0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 07/03/2026 16:30:00 to San Pedro Santa Clara Coach Stop, Mexico City (Mexico) arriving at 09/03/2026 22:30:00. 50 Economy ticket for £154 per person are available. Travel duration is 54h 0m
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Here you will find all operators and timetables for a
Bus from St. Louis, MO to Mexico City
What are the most popular stations in St. Louis, MO and Mexico City?
In St. Louis, MO, you will usually depart from Skinker Boulevard, Lindbergh @ Hackberry NB Bus Stop or Gateway Station, while in Mexico City you will be arriving at Norte Bus Station, Terminal de Autobuses de Oriente (TAPO) or Terminal del Sur, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Mexico City from St. Louis, MO? With 15 connections between 2 Flight and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between St. Louis, MO and Mexico City, you can pay as low as £154 with a Bus from Greyhound US.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Alaska Airlines: you will get to Mexico City in just 7h 50m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting St. Louis, MO and Mexico City are Frontier Airlines, Greyhound US and Delta Air Lines, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in St. Louis, MO and Mexico City is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Sauget, IL or to Moctezuma 2da Secc, and look at flights from St. Louis Lambert Airport, and landing at Felipe Ángeles Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from St. Louis, MO to Mexico City?
The most popular companies between St. Louis, MO and Mexico City, are Frontier Airlines, Greyhound US and Delta Air Lines. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: Greyhound US and FlixBus
Airlines: Frontier Airlines, Delta Air Lines, Alaska Airlines and 2 more.
All you need to know when you travel from St. Louis, MO to Mexico City
Check all information on comfort and services on all modes of transports from St. Louis, MO to Mexico City. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from St. Louis, MO to Mexico City
How can I reach Mexico City from St. Louis, MO?
Every day, there are on average 15 connections between Flight and Bus, with which you can get to Mexico City from St. Louis, MO.
How far is Mexico City from St. Louis, MO?
The distance between St. Louis, MO and Mexico City is 2,300.8 km.
What is the most ecofriendly mode of transport between St. Louis, MO and Mexico City?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 62 kgs of CO2, a train 81 kgs, a car 391 kgs, and a flight 566 kgs.
What is the cheapest mode of transport from St. Louis, MO to Mexico City?
You can get to Mexico City with just £154 by taking a Bus from Greyhound US.
What is the fastest way to get from St. Louis, MO to Mexico City?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Mexico City in just 7h 50m with a Flight from Alaska Airlines.
More routes to St. Louis, MO and to Mexico City
Looking for more options? Here you can see the most popular routes to St. Louis, MO and to Mexico City. Simply click on a connection, and you’ll find all the details about the route!
- Trips to St. Louis, MO
- Atlanta, GA to St. Louis, MO
- Dallas to St. Louis, MO
- Houston to St. Louis, MO
- Monterrey, NL to St. Louis, MO
- Trips to Mexico City
- Acapulco, GR to Mexico City
- Aguascalientes to Mexico City
- Chetumal to Mexico City
- Chihuahua to Mexico City
- Ciudad Obregón to Mexico City
- Culiacán Rosales to Mexico City
- Guadalajara, JC to Mexico City
- Hermosillo to Mexico City
- Juchitán de Zaragoza to Mexico City
- León de los Aldama to Mexico City
- Mazatlán to Mexico City
- Mexicali to Mexico City
- Monterrey, NL to Mexico City
- Oaxaca de Juárez to Mexico City
- Puerto Escondido to Mexico City
- Reynosa to Mexico City
- Saltillo to Mexico City
- San Luis Potosí to Mexico City
- Santiago de Queretaro to Mexico City
- Tampico to Mexico City
- Tijuana, BC to Mexico City
- Veracruz to Mexico City
- Zapopan to Mexico City
- Zihuatanejo to Mexico City
