What is the best way to travel from Santander to Lyon?
Looking for a trip? Check and compare all the available Buses and Flights to Lyon from Santander. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 2 available companies to find your perfect trip!
What is the cheapest way to reach Lyon from Santander?
You can reach Lyon with just £43 by taking a Bus from ALSA, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
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ALSA19h 55m009:00SantanderCoach Station04:55LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Coach Station, Santander (Spain) at 20/12/2025 09:00:00 to Perrache Bus Stop, Lyon (France) arriving at 21/12/2025 04:55:00. 50 Economy ticket for £53 per person are available. Travel duration is 19h 55m
Cheapest Buses Saturday
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ALSA21h 30m020:45SantanderCoach Station18:15LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Coach Station, Santander (Spain) at 21/12/2025 20:45:00 to Perrache Bus Stop, Lyon (France) arriving at 22/12/2025 18:15:00. 50 Economy ticket for £58 per person are available. Travel duration is 21h 30m
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ALSA19h 55m009:00SantanderCoach Station04:55LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Coach Station, Santander (Spain) at 21/12/2025 09:00:00 to Perrache Bus Stop, Lyon (France) arriving at 22/12/2025 04:55:00. 50 Economy ticket for £62 per person are available. Travel duration is 19h 55m
Cheapest Buses Sunday
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ALSA19h 55m009:00SantanderCoach Station04:55LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Coach Station, Santander (Spain) at 22/12/2025 09:00:00 to Perrache Bus Stop, Lyon (France) arriving at 23/12/2025 04:55:00. 50 Economy ticket for £62 per person are available. Travel duration is 19h 55m
Cheapest Buses Monday
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ALSA19h 55m009:00SantanderCoach Station04:55LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Coach Station, Santander (Spain) at 23/12/2025 09:00:00 to Perrache Bus Stop, Lyon (France) arriving at 24/12/2025 04:55:00. 50 Economy ticket for £45 per person are available. Travel duration is 19h 55m
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ALSA21h 30m020:45SantanderCoach Station18:15LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Coach Station, Santander (Spain) at 23/12/2025 20:45:00 to Perrache Bus Stop, Lyon (France) arriving at 24/12/2025 18:15:00. 50 Economy ticket for £45 per person are available. Travel duration is 21h 30m
Cheapest Buses Tuesday
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ALSA16h 14m018:00SantanderCoach Station10:14LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Coach Station, Santander (Spain) at 26/12/2025 18:00:00 to Perrache Bus Stop, Lyon (France) arriving at 27/12/2025 10:14:00. 50 Economy ticket for £43 per person are available. Travel duration is 16h 14m
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ALSA19h 55m009:00SantanderCoach Station04:55LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Coach Station, Santander (Spain) at 26/12/2025 09:00:00 to Perrache Bus Stop, Lyon (France) arriving at 27/12/2025 04:55:00. 50 Economy ticket for £62 per person are available. Travel duration is 19h 55m
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FlixBus19h 40m018:55SantanderCoach Station14:35LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Coach Station, Santander (Spain) at 26/12/2025 18:55:00 to Perrache Bus Stop, Lyon (France) arriving at 27/12/2025 14:35:00. 50 Economy ticket for £151 per person are available. Travel duration is 19h 40m
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Vueling Airlines25h 30m017:30Santander AirportSantander Airport19:00Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Vueling Airlines goes from Santander Airport, Santander Airport (Spain) at 26/12/2025 17:30:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 27/12/2025 19:00:00. 50 Economy ticket for £164 per person are available. Travel duration is 25h 30m
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Vueling Airlines14h 5m017:30Santander AirportSantander Airport07:35Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Vueling Airlines goes from Santander Airport, Santander Airport (Spain) at 26/12/2025 17:30:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 27/12/2025 07:35:00. 50 Economy ticket for £179 per person are available. Travel duration is 14h 5m
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Vueling Airlines14h 5m017:30Santander AirportSantander Airport07:35Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Vueling Airlines goes from Santander Airport, Santander Airport (Spain) at 26/12/2025 17:30:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 27/12/2025 07:35:00. 50 Economy ticket for £202 per person are available. Travel duration is 14h 5m
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Iberia26h 10m021:35Santander AirportSantander Airport23:45Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Iberia goes from Santander Airport, Santander Airport (Spain) at 26/12/2025 21:35:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 27/12/2025 23:45:00. 50 Economy ticket for £230 per person are available. Travel duration is 26h 10m
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Iberia25h 30m017:30Santander AirportSantander Airport19:00Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Iberia goes from Santander Airport, Santander Airport (Spain) at 26/12/2025 17:30:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 27/12/2025 19:00:00. 50 Economy ticket for £232 per person are available. Travel duration is 25h 30m
Cheapest Buses Friday
Cheapest Flights Friday
What are the fastest trips from Santander to Lyon?
You can get to Lyon from Santander in just 14h 5m with a Flight from Vueling Airlines. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
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ALSA19h 55m009:00SantanderCoach Station04:55LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Coach Station, Santander (Spain) at 20/12/2025 09:00:00 to Perrache Bus Stop, Lyon (France) arriving at 21/12/2025 04:55:00. 50 Economy ticket for £53 per person are available. Travel duration is 19h 55m
Fastest Buses Saturday
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ALSA19h 55m009:00SantanderCoach Station04:55LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Coach Station, Santander (Spain) at 21/12/2025 09:00:00 to Perrache Bus Stop, Lyon (France) arriving at 22/12/2025 04:55:00. 50 Economy ticket for £62 per person are available. Travel duration is 19h 55m
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ALSA21h 30m020:45SantanderCoach Station18:15LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Coach Station, Santander (Spain) at 21/12/2025 20:45:00 to Perrache Bus Stop, Lyon (France) arriving at 22/12/2025 18:15:00. 50 Economy ticket for £58 per person are available. Travel duration is 21h 30m
Fastest Buses Sunday
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ALSA19h 55m009:00SantanderCoach Station04:55LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Coach Station, Santander (Spain) at 22/12/2025 09:00:00 to Perrache Bus Stop, Lyon (France) arriving at 23/12/2025 04:55:00. 50 Economy ticket for £62 per person are available. Travel duration is 19h 55m
Fastest Buses Monday
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ALSA19h 55m009:00SantanderCoach Station04:55LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Coach Station, Santander (Spain) at 23/12/2025 09:00:00 to Perrache Bus Stop, Lyon (France) arriving at 24/12/2025 04:55:00. 50 Economy ticket for £45 per person are available. Travel duration is 19h 55m
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ALSA21h 30m020:45SantanderCoach Station18:15LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Coach Station, Santander (Spain) at 23/12/2025 20:45:00 to Perrache Bus Stop, Lyon (France) arriving at 24/12/2025 18:15:00. 50 Economy ticket for £45 per person are available. Travel duration is 21h 30m
Fastest Buses Tuesday
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Vueling Airlines14h 5m017:30Santander AirportSantander Airport07:35Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Vueling Airlines goes from Santander Airport, Santander Airport (Spain) at 26/12/2025 17:30:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 27/12/2025 07:35:00. 50 Economy ticket for £179 per person are available. Travel duration is 14h 5m
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Vueling Airlines14h 5m017:30Santander AirportSantander Airport07:35Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Vueling Airlines goes from Santander Airport, Santander Airport (Spain) at 26/12/2025 17:30:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 27/12/2025 07:35:00. 50 Economy ticket for £202 per person are available. Travel duration is 14h 5m
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Vueling Airlines25h 30m017:30Santander AirportSantander Airport19:00Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Vueling Airlines goes from Santander Airport, Santander Airport (Spain) at 26/12/2025 17:30:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 27/12/2025 19:00:00. 50 Economy ticket for £164 per person are available. Travel duration is 25h 30m
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Iberia25h 30m017:30Santander AirportSantander Airport19:00Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Iberia goes from Santander Airport, Santander Airport (Spain) at 26/12/2025 17:30:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 27/12/2025 19:00:00. 50 Economy ticket for £232 per person are available. Travel duration is 25h 30m
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Iberia26h 10m021:35Santander AirportSantander Airport23:45Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Iberia goes from Santander Airport, Santander Airport (Spain) at 26/12/2025 21:35:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 27/12/2025 23:45:00. 50 Economy ticket for £230 per person are available. Travel duration is 26h 10m
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ALSA16h 14m018:00SantanderCoach Station10:14LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Coach Station, Santander (Spain) at 26/12/2025 18:00:00 to Perrache Bus Stop, Lyon (France) arriving at 27/12/2025 10:14:00. 50 Economy ticket for £43 per person are available. Travel duration is 16h 14m
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FlixBus19h 40m018:55SantanderCoach Station14:35LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Coach Station, Santander (Spain) at 26/12/2025 18:55:00 to Perrache Bus Stop, Lyon (France) arriving at 27/12/2025 14:35:00. 50 Economy ticket for £151 per person are available. Travel duration is 19h 40m
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ALSA19h 55m009:00SantanderCoach Station04:55LyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Coach Station, Santander (Spain) at 26/12/2025 09:00:00 to Perrache Bus Stop, Lyon (France) arriving at 27/12/2025 04:55:00. 50 Economy ticket for £62 per person are available. Travel duration is 19h 55m
Fastest Flights Friday
Fastest Buses Friday
Here you will find all operators and timetables for a
Bus from Santander to Lyon
What are the most popular stations in Santander and Lyon?
In Santander, you will usually depart from Coach Station, Parayas Avenue Coach Stop or Astillero, while in Lyon you will be arriving at Perrache Bus Stop, Perrache Train Station or Part-Dieu Train Station, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Lyon from Santander? With 2 connections between 2 Bus and Flight operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Santander and Lyon, you can pay as low as £43 with a Bus from ALSA.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Vueling Airlines: you will get to Lyon in just 14h 5m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Santander and Lyon are ALSA, Vueling Airlines and Iberia, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Santander and Lyon is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Santander Airport or to Caluire-et-Cuire, and look at flights from Santander Airport, and landing at Lyons St. Exupery Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Santander to Lyon?
The most popular companies between Santander and Lyon, are ALSA, Vueling Airlines and Iberia. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: ALSA and FlixBus
Airlines: Vueling Airlines and Iberia
All you need to know when you travel from Santander to Lyon
Check all information on comfort and services on all modes of transports from Santander to Lyon. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Santander to Lyon
How can I reach Lyon from Santander?
Every day, there are on average 2 connections between Bus and Flight, with which you can get to Lyon from Santander.
How far is Lyon from Santander?
The distance between Santander and Lyon is 729.9 km.
What is the most ecofriendly mode of transport between Santander and Lyon?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 20 kgs of CO2, a train 26 kgs, a car 124 kgs, and a flight 180 kgs.
What is the cheapest mode of transport from Santander to Lyon?
You can get to Lyon with just £43 by taking a Bus from ALSA.
What is the fastest way to get from Santander to Lyon?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Lyon in just 14h 5m with a Flight from Vueling Airlines.
More routes to Santander and to Lyon
Looking for more options? Here you can see the most popular routes to Santander and to Lyon. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Santander
- A Coruña to Santander
- Adolfo Suárez Madrid-Barajas Airport to Santander
- Barcelona to Santander
- Bilbao to Santander
- Burgos to Santander
- Granada to Santander
- Logroño to Santander
- London to Santander
- Madrid to Santander
- Oviedo to Santander
- Pamplona to Santander
- Salamanca (ES) to Santander
- San Sebastian to Santander
- Santiago de Compostela to Santander
- Toulouse to Santander
- Valencia to Santander
- Valladolid to Santander
- Vigo to Santander
- Vitoria-Gasteiz to Santander
- Zaragoza to Santander
- Trips to Lyon
- Alicante to Lyon
- Annecy to Lyon
- Barcelona to Lyon
- Basel to Lyon
- Bologna to Lyon
- Bordeaux to Lyon
- Braga to Lyon
- Caen to Lyon
- Dusseldorf to Lyon
- Geneva to Lyon
- Genoa to Lyon
- Lille to Lyon
- Lisbon to Lyon
- London to Lyon
- Lyons St. Exupery Airport to Lyon
- Marseille to Lyon
- Milan to Lyon
- Nancy to Lyon
- Paris to Lyon
- Rome to Lyon
- San Sebastian to Lyon
- Toulouse to Lyon
- Turin to Lyon
- Valencia to Lyon
