What is the best way to travel from Prague Airport to Lyon?
Looking for a trip? Check and compare all the available Flights and Buses to Lyon from Prague Airport. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 1 available companies to find your perfect trip!
What is the cheapest way to reach Lyon from Prague Airport?
You can reach Lyon with just £50 by taking a Flight from EasyJet Airline, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
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FlixBus18h 55m013:20Prague AirportPrague Airport - T1/208:15LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 03/11/2026 13:20:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 04/11/2026 08:15:00. 50 Economy ticket for £70 per person are available. Travel duration is 18h 55m
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FlixBus21h 0m017:45Prague AirportPrague Airport - T1/214:45LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 03/11/2026 17:45:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 04/11/2026 14:45:00. 50 Economy ticket for £74 per person are available. Travel duration is 21h 0m
Cheapest Buses Tuesday
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FlixBus17h 50m018:50Prague AirportPrague Airport - T1/212:40LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 04/11/2026 18:50:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 05/11/2026 12:40:00. 50 Economy ticket for £52 per person are available. Travel duration is 17h 50m
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FlixBus23h 25m022:15Prague AirportPrague Airport - T1/221:40LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 04/11/2026 22:15:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 05/11/2026 21:40:00. 50 Economy ticket for £52 per person are available. Travel duration is 23h 25m
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FlixBus18h 55m013:20Prague AirportPrague Airport - T1/208:15LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 04/11/2026 13:20:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 05/11/2026 08:15:00. 50 Economy ticket for £53 per person are available. Travel duration is 18h 55m
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Wizz Air23h 55m017:00Prague AirportPrague Airport16:55Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Wizz Air goes from Prague Airport, Prague Airport (Czech Republic) at 04/11/2026 17:00:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 05/11/2026 16:55:00. 50 Economy ticket for £52 per person are available. Travel duration is 23h 55m
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EasyJet Airline20h 0m020:55Prague AirportPrague Airport16:55Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from EasyJet Airline goes from Prague Airport, Prague Airport (Czech Republic) at 04/11/2026 20:55:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 05/11/2026 16:55:00. 50 Economy ticket for £66 per person are available. Travel duration is 20h 0m
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Pegasus Group LTD19h 30m018:15Prague AirportPrague Airport13:45Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Pegasus Group LTD goes from Prague Airport, Prague Airport (Czech Republic) at 04/11/2026 18:15:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 05/11/2026 13:45:00. 50 Economy ticket for £124 per person are available. Travel duration is 19h 30m
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Smartwings11h 10m011:45Prague AirportPrague Airport22:55Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Smartwings goes from Prague Airport, Prague Airport (Czech Republic) at 04/11/2026 11:45:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 04/11/2026 22:55:00. 50 Economy ticket for £132 per person are available. Travel duration is 11h 10m
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Lufthansa6h 5m006:10Prague AirportPrague Airport12:15Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Lufthansa goes from Prague Airport, Prague Airport (Czech Republic) at 04/11/2026 06:10:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 04/11/2026 12:15:00. 50 Economy ticket for £135 per person are available. Travel duration is 6h 5m
Cheapest Buses Wednesday
Cheapest Flights Wednesday
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FlixBus17h 50m018:50Prague AirportPrague Airport - T1/212:40LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 05/11/2026 18:50:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 06/11/2026 12:40:00. 50 Economy ticket for £52 per person are available. Travel duration is 17h 50m
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FlixBus22h 5m022:45Prague AirportPrague Airport - T1/220:50LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 05/11/2026 22:45:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 06/11/2026 20:50:00. 50 Economy ticket for £53 per person are available. Travel duration is 22h 5m
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FlixBus18h 55m013:20Prague AirportPrague Airport - T1/208:15LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 05/11/2026 13:20:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 06/11/2026 08:15:00. 50 Economy ticket for £54 per person are available. Travel duration is 18h 55m
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EasyJet Airline1h 50m012:30Prague AirportPrague Airport14:20Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from EasyJet Airline goes from Prague Airport, Prague Airport (Czech Republic) at 05/11/2026 12:30:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 05/11/2026 14:20:00. 50 Economy ticket for £62 per person are available. Travel duration is 1h 50m
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Wizz Air22h 0m022:45Prague AirportPrague Airport20:45Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Wizz Air goes from Prague Airport, Prague Airport (Czech Republic) at 05/11/2026 22:45:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 06/11/2026 20:45:00. 50 Economy ticket for £74 per person are available. Travel duration is 22h 0m
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Vueling Airlines11h 40m020:55Prague AirportPrague Airport08:35Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Vueling Airlines goes from Prague Airport, Prague Airport (Czech Republic) at 05/11/2026 20:55:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 06/11/2026 08:35:00. 50 Economy ticket for £78 per person are available. Travel duration is 11h 40m
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Smartwings12h 30m011:20Prague AirportPrague Airport23:50Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Smartwings goes from Prague Airport, Prague Airport (Czech Republic) at 05/11/2026 11:20:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 05/11/2026 23:50:00. 50 Economy ticket for £135 per person are available. Travel duration is 12h 30m
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Austrian Airlines4h 40m007:25Prague AirportPrague Airport12:05Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Austrian Airlines goes from Prague Airport, Prague Airport (Czech Republic) at 05/11/2026 07:25:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 05/11/2026 12:05:00. 50 Economy ticket for £137 per person are available. Travel duration is 4h 40m
Cheapest Buses Thursday
Cheapest Flights Thursday
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EasyJet Airline1h 50m010:15Prague AirportPrague Airport12:05Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from EasyJet Airline goes from Prague Airport, Prague Airport (Czech Republic) at 06/11/2026 10:15:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 06/11/2026 12:05:00. 50 Economy ticket for £50 per person are available. Travel duration is 1h 50m
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Vueling Airlines10h 30m010:45Prague AirportPrague Airport21:15Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Vueling Airlines goes from Prague Airport, Prague Airport (Czech Republic) at 06/11/2026 10:45:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 06/11/2026 21:15:00. 50 Economy ticket for £98 per person are available. Travel duration is 10h 30m
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Wizz Air23h 50m022:45Prague AirportPrague Airport22:35Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Wizz Air goes from Prague Airport, Prague Airport (Czech Republic) at 06/11/2026 22:45:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 07/11/2026 22:35:00. 50 Economy ticket for £98 per person are available. Travel duration is 23h 50m
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Smartwings9h 40m011:35Prague AirportPrague Airport21:15Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Smartwings goes from Prague Airport, Prague Airport (Czech Republic) at 06/11/2026 11:35:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 06/11/2026 21:15:00. 50 Economy ticket for £129 per person are available. Travel duration is 9h 40m
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Lufthansa7h 5m006:10Prague AirportPrague Airport13:15Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Lufthansa goes from Prague Airport, Prague Airport (Czech Republic) at 06/11/2026 06:10:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 06/11/2026 13:15:00. 50 Economy ticket for £135 per person are available. Travel duration is 7h 5m
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FlixBus17h 50m018:50Prague AirportPrague Airport - T1/212:40LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 06/11/2026 18:50:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 07/11/2026 12:40:00. 50 Economy ticket for £58 per person are available. Travel duration is 17h 50m
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FlixBus22h 5m022:45Prague AirportPrague Airport - T1/220:50LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 06/11/2026 22:45:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 07/11/2026 20:50:00. 50 Economy ticket for £58 per person are available. Travel duration is 22h 5m
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FlixBus21h 20m007:00Prague AirportPrague Airport - T1/204:20LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 06/11/2026 07:00:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 07/11/2026 04:20:00. 50 Economy ticket for £65 per person are available. Travel duration is 21h 20m
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FlixBus18h 55m013:20Prague AirportPrague Airport - T1/208:15LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 06/11/2026 13:20:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 07/11/2026 08:15:00. 50 Economy ticket for £83 per person are available. Travel duration is 18h 55m
Cheapest Flights Friday
Cheapest Buses Friday
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FlixBus17h 50m006:30Prague AirportPrague Airport - T1/200:20LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 07/11/2026 06:30:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 08/11/2026 00:20:00. 50 Economy ticket for £53 per person are available. Travel duration is 17h 50m
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FlixBus17h 50m018:50Prague AirportPrague Airport - T1/212:40LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 07/11/2026 18:50:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 08/11/2026 12:40:00. 50 Economy ticket for £53 per person are available. Travel duration is 17h 50m
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FlixBus21h 20m007:00Prague AirportPrague Airport - T1/204:20LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 07/11/2026 07:00:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 08/11/2026 04:20:00. 50 Economy ticket for £54 per person are available. Travel duration is 21h 20m
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FlixBus18h 55m013:20Prague AirportPrague Airport - T1/208:15LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 07/11/2026 13:20:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 08/11/2026 08:15:00. 50 Economy ticket for £59 per person are available. Travel duration is 18h 55m
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FlixBus22h 5m022:45Prague AirportPrague Airport - T1/220:50LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 07/11/2026 22:45:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 08/11/2026 20:50:00. 50 Economy ticket for £61 per person are available. Travel duration is 22h 5m
Cheapest Buses Saturday
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FlixBus22h 5m022:45Prague AirportPrague Airport - T1/220:50LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 08/11/2026 22:45:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 09/11/2026 20:50:00. 50 Economy ticket for £65 per person are available. Travel duration is 22h 5m
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FlixBus17h 50m018:50Prague AirportPrague Airport - T1/212:40LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 08/11/2026 18:50:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 09/11/2026 12:40:00. 50 Economy ticket for £70 per person are available. Travel duration is 17h 50m
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FlixBus21h 20m007:00Prague AirportPrague Airport - T1/204:20LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 08/11/2026 07:00:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 09/11/2026 04:20:00. 50 Economy ticket for £103 per person are available. Travel duration is 21h 20m
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FlixBus20h 55m011:20Prague AirportPrague Airport - T1/208:15LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 08/11/2026 11:20:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 09/11/2026 08:15:00. 50 Economy ticket for £108 per person are available. Travel duration is 20h 55m
Cheapest Buses Sunday
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FlixBus21h 15m017:45Prague AirportPrague Airport - T1/215:00LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 09/11/2026 17:45:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 10/11/2026 15:00:00. 50 Economy ticket for £52 per person are available. Travel duration is 21h 15m
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FlixBus21h 20m007:00Prague AirportPrague Airport - T1/204:20LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 09/11/2026 07:00:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 10/11/2026 04:20:00. 50 Economy ticket for £54 per person are available. Travel duration is 21h 20m
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FlixBus18h 55m013:20Prague AirportPrague Airport - T1/208:15LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 09/11/2026 13:20:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 10/11/2026 08:15:00. 50 Economy ticket for £56 per person are available. Travel duration is 18h 55m
Cheapest Buses Monday
What are the fastest trips from Prague Airport to Lyon?
You can get to Lyon from Prague Airport in just 1h 50m with a Flight from EasyJet Airline. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
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FlixBus18h 55m013:20Prague AirportPrague Airport - T1/208:15LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 03/11/2026 13:20:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 04/11/2026 08:15:00. 50 Economy ticket for £70 per person are available. Travel duration is 18h 55m
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FlixBus21h 0m017:45Prague AirportPrague Airport - T1/214:45LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 03/11/2026 17:45:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 04/11/2026 14:45:00. 50 Economy ticket for £74 per person are available. Travel duration is 21h 0m
Fastest Buses Tuesday
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Lufthansa6h 5m006:10Prague AirportPrague Airport12:15Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Lufthansa goes from Prague Airport, Prague Airport (Czech Republic) at 04/11/2026 06:10:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 04/11/2026 12:15:00. 50 Economy ticket for £135 per person are available. Travel duration is 6h 5m
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Smartwings11h 10m011:45Prague AirportPrague Airport22:55Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Smartwings goes from Prague Airport, Prague Airport (Czech Republic) at 04/11/2026 11:45:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 04/11/2026 22:55:00. 50 Economy ticket for £132 per person are available. Travel duration is 11h 10m
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Pegasus Group LTD19h 30m018:15Prague AirportPrague Airport13:45Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Pegasus Group LTD goes from Prague Airport, Prague Airport (Czech Republic) at 04/11/2026 18:15:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 05/11/2026 13:45:00. 50 Economy ticket for £124 per person are available. Travel duration is 19h 30m
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EasyJet Airline20h 0m020:55Prague AirportPrague Airport16:55Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from EasyJet Airline goes from Prague Airport, Prague Airport (Czech Republic) at 04/11/2026 20:55:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 05/11/2026 16:55:00. 50 Economy ticket for £66 per person are available. Travel duration is 20h 0m
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Wizz Air23h 55m017:00Prague AirportPrague Airport16:55Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Wizz Air goes from Prague Airport, Prague Airport (Czech Republic) at 04/11/2026 17:00:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 05/11/2026 16:55:00. 50 Economy ticket for £52 per person are available. Travel duration is 23h 55m
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FlixBus17h 50m018:50Prague AirportPrague Airport - T1/212:40LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 04/11/2026 18:50:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 05/11/2026 12:40:00. 50 Economy ticket for £52 per person are available. Travel duration is 17h 50m
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FlixBus18h 55m013:20Prague AirportPrague Airport - T1/208:15LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 04/11/2026 13:20:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 05/11/2026 08:15:00. 50 Economy ticket for £53 per person are available. Travel duration is 18h 55m
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FlixBus23h 25m022:15Prague AirportPrague Airport - T1/221:40LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 04/11/2026 22:15:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 05/11/2026 21:40:00. 50 Economy ticket for £52 per person are available. Travel duration is 23h 25m
Fastest Flights Wednesday
Fastest Buses Wednesday
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EasyJet Airline1h 50m012:30Prague AirportPrague Airport14:20Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from EasyJet Airline goes from Prague Airport, Prague Airport (Czech Republic) at 05/11/2026 12:30:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 05/11/2026 14:20:00. 50 Economy ticket for £62 per person are available. Travel duration is 1h 50m
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Austrian Airlines4h 40m007:25Prague AirportPrague Airport12:05Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Austrian Airlines goes from Prague Airport, Prague Airport (Czech Republic) at 05/11/2026 07:25:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 05/11/2026 12:05:00. 50 Economy ticket for £137 per person are available. Travel duration is 4h 40m
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Vueling Airlines11h 40m020:55Prague AirportPrague Airport08:35Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Vueling Airlines goes from Prague Airport, Prague Airport (Czech Republic) at 05/11/2026 20:55:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 06/11/2026 08:35:00. 50 Economy ticket for £78 per person are available. Travel duration is 11h 40m
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Smartwings12h 30m011:20Prague AirportPrague Airport23:50Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Smartwings goes from Prague Airport, Prague Airport (Czech Republic) at 05/11/2026 11:20:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 05/11/2026 23:50:00. 50 Economy ticket for £135 per person are available. Travel duration is 12h 30m
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Wizz Air22h 0m022:45Prague AirportPrague Airport20:45Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Wizz Air goes from Prague Airport, Prague Airport (Czech Republic) at 05/11/2026 22:45:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 06/11/2026 20:45:00. 50 Economy ticket for £74 per person are available. Travel duration is 22h 0m
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FlixBus17h 50m018:50Prague AirportPrague Airport - T1/212:40LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 05/11/2026 18:50:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 06/11/2026 12:40:00. 50 Economy ticket for £52 per person are available. Travel duration is 17h 50m
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FlixBus18h 55m013:20Prague AirportPrague Airport - T1/208:15LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 05/11/2026 13:20:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 06/11/2026 08:15:00. 50 Economy ticket for £54 per person are available. Travel duration is 18h 55m
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FlixBus22h 5m022:45Prague AirportPrague Airport - T1/220:50LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 05/11/2026 22:45:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 06/11/2026 20:50:00. 50 Economy ticket for £53 per person are available. Travel duration is 22h 5m
Fastest Flights Thursday
Fastest Buses Thursday
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EasyJet Airline1h 50m010:15Prague AirportPrague Airport12:05Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from EasyJet Airline goes from Prague Airport, Prague Airport (Czech Republic) at 06/11/2026 10:15:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 06/11/2026 12:05:00. 50 Economy ticket for £50 per person are available. Travel duration is 1h 50m
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Lufthansa7h 5m006:10Prague AirportPrague Airport13:15Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Lufthansa goes from Prague Airport, Prague Airport (Czech Republic) at 06/11/2026 06:10:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 06/11/2026 13:15:00. 50 Economy ticket for £135 per person are available. Travel duration is 7h 5m
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Smartwings9h 40m011:35Prague AirportPrague Airport21:15Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Smartwings goes from Prague Airport, Prague Airport (Czech Republic) at 06/11/2026 11:35:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 06/11/2026 21:15:00. 50 Economy ticket for £129 per person are available. Travel duration is 9h 40m
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Vueling Airlines10h 30m010:45Prague AirportPrague Airport21:15Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Vueling Airlines goes from Prague Airport, Prague Airport (Czech Republic) at 06/11/2026 10:45:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 06/11/2026 21:15:00. 50 Economy ticket for £98 per person are available. Travel duration is 10h 30m
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Wizz Air23h 50m022:45Prague AirportPrague Airport22:35Lyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Wizz Air goes from Prague Airport, Prague Airport (Czech Republic) at 06/11/2026 22:45:00 to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 07/11/2026 22:35:00. 50 Economy ticket for £98 per person are available. Travel duration is 23h 50m
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FlixBus17h 50m018:50Prague AirportPrague Airport - T1/212:40LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 06/11/2026 18:50:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 07/11/2026 12:40:00. 50 Economy ticket for £58 per person are available. Travel duration is 17h 50m
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FlixBus18h 55m013:20Prague AirportPrague Airport - T1/208:15LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 06/11/2026 13:20:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 07/11/2026 08:15:00. 50 Economy ticket for £83 per person are available. Travel duration is 18h 55m
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FlixBus21h 20m007:00Prague AirportPrague Airport - T1/204:20LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 06/11/2026 07:00:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 07/11/2026 04:20:00. 50 Economy ticket for £65 per person are available. Travel duration is 21h 20m
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FlixBus22h 5m022:45Prague AirportPrague Airport - T1/220:50LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 06/11/2026 22:45:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 07/11/2026 20:50:00. 50 Economy ticket for £58 per person are available. Travel duration is 22h 5m
Fastest Flights Friday
Fastest Buses Friday
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FlixBus17h 50m006:30Prague AirportPrague Airport - T1/200:20LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 07/11/2026 06:30:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 08/11/2026 00:20:00. 50 Economy ticket for £53 per person are available. Travel duration is 17h 50m
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FlixBus17h 50m018:50Prague AirportPrague Airport - T1/212:40LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 07/11/2026 18:50:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 08/11/2026 12:40:00. 50 Economy ticket for £53 per person are available. Travel duration is 17h 50m
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FlixBus18h 55m013:20Prague AirportPrague Airport - T1/208:15LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 07/11/2026 13:20:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 08/11/2026 08:15:00. 50 Economy ticket for £59 per person are available. Travel duration is 18h 55m
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FlixBus21h 20m007:00Prague AirportPrague Airport - T1/204:20LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 07/11/2026 07:00:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 08/11/2026 04:20:00. 50 Economy ticket for £54 per person are available. Travel duration is 21h 20m
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FlixBus22h 5m022:45Prague AirportPrague Airport - T1/220:50LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 07/11/2026 22:45:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 08/11/2026 20:50:00. 50 Economy ticket for £61 per person are available. Travel duration is 22h 5m
Fastest Buses Saturday
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FlixBus17h 50m018:50Prague AirportPrague Airport - T1/212:40LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 08/11/2026 18:50:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 09/11/2026 12:40:00. 50 Economy ticket for £70 per person are available. Travel duration is 17h 50m
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FlixBus20h 55m011:20Prague AirportPrague Airport - T1/208:15LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 08/11/2026 11:20:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 09/11/2026 08:15:00. 50 Economy ticket for £108 per person are available. Travel duration is 20h 55m
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FlixBus21h 20m007:00Prague AirportPrague Airport - T1/204:20LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 08/11/2026 07:00:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 09/11/2026 04:20:00. 50 Economy ticket for £103 per person are available. Travel duration is 21h 20m
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FlixBus22h 5m022:45Prague AirportPrague Airport - T1/220:50LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 08/11/2026 22:45:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 09/11/2026 20:50:00. 50 Economy ticket for £65 per person are available. Travel duration is 22h 5m
Fastest Buses Sunday
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FlixBus18h 55m013:20Prague AirportPrague Airport - T1/208:15LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 09/11/2026 13:20:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 10/11/2026 08:15:00. 50 Economy ticket for £56 per person are available. Travel duration is 18h 55m
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FlixBus21h 15m017:45Prague AirportPrague Airport - T1/215:00LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 09/11/2026 17:45:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 10/11/2026 15:00:00. 50 Economy ticket for £52 per person are available. Travel duration is 21h 15m
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FlixBus21h 20m007:00Prague AirportPrague Airport - T1/204:20LyonLyon Avenue Tony Garnier Coach Stop0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 09/11/2026 07:00:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 10/11/2026 04:20:00. 50 Economy ticket for £54 per person are available. Travel duration is 21h 20m
Fastest Buses Monday
Here you will find all operators and timetables for a
Bus from Prague Airport to Lyon
What are the most popular stations in Prague Airport and Lyon?
In Prague Airport, you will usually depart from Prague Airport - T1/2 or Prague Airport, while in Lyon you will be arriving at Part-Dieu Train Station, Perrache Train Station or Perrache Bus Stop, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Lyon from Prague Airport? With 5 connections between 1 Bus and Flight operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Prague Airport and Lyon, you can pay as low as £50 with a Flight from EasyJet Airline.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from EasyJet Airline: you will get to Lyon in just 1h 50m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Prague Airport and Lyon are FlixBus, Wizz Air and EasyJet Airline, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Prague Airport and Lyon is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Horoměřice or to Caluire-et-Cuire, and look at flights from , and landing at Lyons St. Exupery Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Prague Airport to Lyon?
The most popular companies between Prague Airport and Lyon, are FlixBus, Wizz Air and EasyJet Airline. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: FlixBus
Airlines: Wizz Air, EasyJet Airline, Smartwings and 4 more.
All you need to know when you travel from Prague Airport to Lyon
Check all information on comfort and services on all modes of transports from Prague Airport to Lyon. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Prague Airport to Lyon
How can I reach Lyon from Prague Airport?
Every day, there are on average 5 connections between Bus and Flight, with which you can get to Lyon from Prague Airport.
How far is Lyon from Prague Airport?
The distance between Prague Airport and Lyon is 852.0 km.
What is the most ecofriendly mode of transport between Prague Airport and Lyon?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 23 kgs of CO2, a train 30 kgs, a car 145 kgs, and a flight 210 kgs.
What is the cheapest mode of transport from Prague Airport to Lyon?
You can get to Lyon with just £50 by taking a Flight from EasyJet Airline.
What is the fastest way to get from Prague Airport to Lyon?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Lyon in just 1h 50m with a Flight from EasyJet Airline.
More routes to Prague Airport and to Lyon
Looking for more options? Here you can see the most popular routes to Prague Airport and to Lyon. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Prague Airport
- Berlin Brandenburg Airport to Prague Airport
- Berlin to Prague Airport
- Brno to Prague Airport
- Dresden to Prague Airport
- Hradec Kralove to Prague Airport
- Jihlava to Prague Airport
- London to Prague Airport
- Munich to Prague Airport
- Nuremberg to Prague Airport
- Paris to Prague Airport
- Pilsen to Prague Airport
- Prague to Prague Airport
- Regensburg to Prague Airport
- Teplice to Prague Airport
- Wroclaw to Prague Airport
- Trips to Lyon
- Alicante to Lyon
- Barcelona to Lyon
- Basel to Lyon
- Berlin to Lyon
- Bordeaux to Lyon
- Brussels to Lyon
- Clermont-Ferrand to Lyon
- Geneva Airport to Lyon
- Geneva to Lyon
- Grenoble to Lyon
- Lausanne to Lyon
- London to Lyon
- Lyons St. Exupery Airport to Lyon
- Marseille to Lyon
- Milan to Lyon
- Nice to Lyon
- Nimes to Lyon
- Paris Orly Airport to Lyon
- Paris to Lyon
- Perpignan to Lyon
- Toulouse to Lyon
- Turin to Lyon
- Valencia to Lyon
- Viseu to Lyon
