What is the best way to travel from Chicago to San Diego?
Looking for a trip? Check and compare all the available Flights and Buses to San Diego from Chicago. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 2 available companies to find your perfect trip!
What is the cheapest way to reach San Diego from Chicago?
You can reach San Diego with just £112 by taking a Flight from Viva Aerobus, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
-
Volaris21h 21m023:59Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center19:20Tijuana AirportTijuana Airport0EconomyA Flight from Volaris goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 05/02/2026 23:59:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 06/02/2026 19:20:00. 50 Economy ticket for £132 per person are available. Travel duration is 21h 21m
-
Volaris19h 2m006:23Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center23:25Tijuana AirportTijuana Airport0EconomyA Flight from Volaris goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 05/02/2026 06:23:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 05/02/2026 23:25:00. 50 Economy ticket for £138 per person are available. Travel duration is 19h 2m
-
Aeroméxico17h 46m014:54Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center06:40Tijuana AirportTijuana Airport0EconomyA Flight from Aeroméxico goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 05/02/2026 14:54:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 06/02/2026 06:40:00. 50 Economy ticket for £204 per person are available. Travel duration is 17h 46m
-
Aeroméxico14h 24m013:26Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center01:50Tijuana AirportTijuana Airport0EconomyA Flight from Aeroméxico goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 05/02/2026 13:26:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 06/02/2026 01:50:00. 50 Economy ticket for £240 per person are available. Travel duration is 14h 24m
-
Frontier Airlines11h 55m007:11Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center17:06Tijuana AirportTijuana Airport0EconomyA Flight from Frontier Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 05/02/2026 07:11:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 05/02/2026 17:06:00. 50 Economy ticket for £274 per person are available. Travel duration is 11h 55m
-
Greyhound US62h 35m023:10ChicagoUnion Station11:45San DiegoOld Town Transit Center0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 05/02/2026 23:10:00 to Old Town Transit Center, San Diego (USA) arriving at 08/02/2026 11:45:00. 50 Economy ticket for £179 per person are available. Travel duration is 62h 35m
-
Greyhound US57h 35m010:00ChicagoUnion Station17:35San DiegoLa Jolla Village0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 05/02/2026 10:00:00 to La Jolla Village, San Diego (USA) arriving at 07/02/2026 17:35:00. 50 Economy ticket for £179 per person are available. Travel duration is 57h 35m
-
Greyhound US60h 30m023:10ChicagoUnion Station09:40San DiegoLa Jolla Village0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 05/02/2026 23:10:00 to La Jolla Village, San Diego (USA) arriving at 08/02/2026 09:40:00. 50 Economy ticket for £179 per person are available. Travel duration is 60h 30m
-
Greyhound US52h 50m014:45ChicagoDowntown Coach Station17:35San DiegoLa Jolla Village0EconomyA Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 05/02/2026 14:45:00 to La Jolla Village, San Diego (USA) arriving at 07/02/2026 17:35:00. 50 Economy ticket for £179 per person are available. Travel duration is 52h 50m
-
Greyhound US62h 15m010:00ChicagoUnion Station22:15San DiegoSeaport Village0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 05/02/2026 10:00:00 to Seaport Village, San Diego (USA) arriving at 07/02/2026 22:15:00. 50 Economy ticket for £180 per person are available. Travel duration is 62h 15m
Cheapest Flights Thursday
Cheapest Buses Thursday
-
Volaris32h 30m023:59Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center06:29Tijuana AirportTijuana Airport0EconomyA Flight from Volaris goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 07/02/2026 23:59:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 09/02/2026 06:29:00. 50 Economy ticket for £130 per person are available. Travel duration is 32h 30m
-
Volaris24h 0m023:59Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center21:59Tijuana AirportTijuana Airport0EconomyA Flight from Volaris goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 07/02/2026 23:59:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 08/02/2026 21:59:00. 50 Economy ticket for £139 per person are available. Travel duration is 24h 0m
-
Viva Aerobus26h 33m000:15Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center00:48Tijuana AirportTijuana Airport0EconomyA Flight from Viva Aerobus goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 07/02/2026 00:15:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 08/02/2026 00:48:00. 50 Economy ticket for £142 per person are available. Travel duration is 26h 33m
-
Viva Aerobus23h 44m000:15Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center21:59Tijuana AirportTijuana Airport0EconomyA Flight from Viva Aerobus goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 07/02/2026 00:15:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 07/02/2026 21:59:00. 50 Economy ticket for £144 per person are available. Travel duration is 23h 44m
-
Aeroméxico18h 21m014:54Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center07:15Tijuana AirportTijuana Airport0EconomyA Flight from Aeroméxico goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 07/02/2026 14:54:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 08/02/2026 07:15:00. 50 Economy ticket for £194 per person are available. Travel duration is 18h 21m
-
Greyhound US63h 10m023:10ChicagoUnion Station12:20San DiegoSan Ysidro Transit Center0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 07/02/2026 23:10:00 to San Ysidro Transit Center, San Diego (USA) arriving at 10/02/2026 12:20:00. 50 Economy ticket for £229 per person are available. Travel duration is 63h 10m
-
Greyhound US58h 20m010:00ChicagoUnion Station18:20San DiegoSan Ysidro Transit Center0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 07/02/2026 10:00:00 to San Ysidro Transit Center, San Diego (USA) arriving at 09/02/2026 18:20:00. 50 Economy ticket for £236 per person are available. Travel duration is 58h 20m
-
FlixBus51h 50m016:30ChicagoDowntown Coach Station18:20San DiegoSan Ysidro Transit Center0EconomyA Bus from FlixBus goes from Downtown Coach Station, Chicago (USA) at 07/02/2026 16:30:00 to San Ysidro Transit Center, San Diego (USA) arriving at 09/02/2026 18:20:00. 50 Economy ticket for £236 per person are available. Travel duration is 51h 50m
-
Greyhound US52h 39m012:01ChicagoDowntown Coach Station14:40San DiegoSan Ysidro Transit Center0EconomyA Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 07/02/2026 12:01:00 to San Ysidro Transit Center, San Diego (USA) arriving at 09/02/2026 14:40:00. 50 Economy ticket for £239 per person are available. Travel duration is 52h 39m
Cheapest Flights Saturday
Cheapest Buses Saturday
-
Volaris20h 6m012:59Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center07:05Tijuana AirportTijuana Airport0EconomyA Flight from Volaris goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 08/02/2026 12:59:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 09/02/2026 07:05:00. 50 Economy ticket for £141 per person are available. Travel duration is 20h 6m
-
Spirit Airlines15h 55m006:05Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center20:00Tijuana AirportTijuana Airport0EconomyA Flight from Spirit Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 08/02/2026 06:05:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 08/02/2026 20:00:00. 50 Economy ticket for £154 per person are available. Travel duration is 15h 55m
-
Viva Aerobus10h 17m000:15Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center08:32Tijuana AirportTijuana Airport0EconomyA Flight from Viva Aerobus goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 08/02/2026 00:15:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 08/02/2026 08:32:00. 50 Economy ticket for £166 per person are available. Travel duration is 10h 17m
-
Aeroméxico19h 39m013:26Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center07:05Tijuana AirportTijuana Airport0EconomyA Flight from Aeroméxico goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 08/02/2026 13:26:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 09/02/2026 07:05:00. 50 Economy ticket for £205 per person are available. Travel duration is 19h 39m
-
Frontier Airlines11h 55m007:11Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center17:06Tijuana AirportTijuana Airport0EconomyA Flight from Frontier Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 08/02/2026 07:11:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 08/02/2026 17:06:00. 50 Economy ticket for £240 per person are available. Travel duration is 11h 55m
Cheapest Flights Sunday
-
Viva Aerobus11h 37m001:20Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center10:57Tijuana AirportTijuana Airport0EconomyA Flight from Viva Aerobus goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 10/02/2026 01:20:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 10/02/2026 10:57:00. 50 Economy ticket for £112 per person are available. Travel duration is 11h 37m
-
Volaris32h 21m012:59Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center19:20Tijuana AirportTijuana Airport0EconomyA Flight from Volaris goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 10/02/2026 12:59:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 11/02/2026 19:20:00. 50 Economy ticket for £114 per person are available. Travel duration is 32h 21m
-
Spirit Airlines13h 1m006:05Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center17:06Tijuana AirportTijuana Airport0EconomyA Flight from Spirit Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 10/02/2026 06:05:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 10/02/2026 17:06:00. 50 Economy ticket for £126 per person are available. Travel duration is 13h 1m
-
Frontier Airlines11h 11m007:55Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center17:06Tijuana AirportTijuana Airport0EconomyA Flight from Frontier Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 10/02/2026 07:55:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 10/02/2026 17:06:00. 50 Economy ticket for £212 per person are available. Travel duration is 11h 11m
-
Aeroméxico17h 46m014:54Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center06:40Tijuana AirportTijuana Airport0EconomyA Flight from Aeroméxico goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 10/02/2026 14:54:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 11/02/2026 06:40:00. 50 Economy ticket for £234 per person are available. Travel duration is 17h 46m
-
Greyhound US60h 55m023:10ChicagoUnion Station10:05San DiegoSeaport Village0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 10/02/2026 23:10:00 to Seaport Village, San Diego (USA) arriving at 13/02/2026 10:05:00. 50 Economy ticket for £192 per person are available. Travel duration is 60h 55m
-
Greyhound US52h 9m012:01ChicagoDowntown Coach Station14:10San DiegoOld Town Transit Center0EconomyA Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 10/02/2026 12:01:00 to Old Town Transit Center, San Diego (USA) arriving at 12/02/2026 14:10:00. 50 Economy ticket for £192 per person are available. Travel duration is 52h 9m
-
Greyhound US51h 39m012:01ChicagoDowntown Coach Station13:40San DiegoLa Jolla Village0EconomyA Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 10/02/2026 12:01:00 to La Jolla Village, San Diego (USA) arriving at 12/02/2026 13:40:00. 50 Economy ticket for £192 per person are available. Travel duration is 51h 39m
-
FlixBus51h 40m016:30ChicagoDowntown Coach Station18:10San DiegoOld Town Transit Center0EconomyA Bus from FlixBus goes from Downtown Coach Station, Chicago (USA) at 10/02/2026 16:30:00 to Old Town Transit Center, San Diego (USA) arriving at 12/02/2026 18:10:00. 50 Economy ticket for £192 per person are available. Travel duration is 51h 40m
-
FlixBus51h 5m016:30ChicagoDowntown Coach Station17:35San DiegoLa Jolla Village0EconomyA Bus from FlixBus goes from Downtown Coach Station, Chicago (USA) at 10/02/2026 16:30:00 to La Jolla Village, San Diego (USA) arriving at 12/02/2026 17:35:00. 50 Economy ticket for £192 per person are available. Travel duration is 51h 5m
Cheapest Flights Tuesday
Cheapest Buses Tuesday
-
Volaris14h 51m012:59Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center01:50Tijuana AirportTijuana Airport0EconomyA Flight from Volaris goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 11/02/2026 12:59:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 12/02/2026 01:50:00. 50 Economy ticket for £158 per person are available. Travel duration is 14h 51m
-
Volaris20h 6m012:59Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center07:05Tijuana AirportTijuana Airport0EconomyA Flight from Volaris goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 11/02/2026 12:59:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 12/02/2026 07:05:00. 50 Economy ticket for £164 per person are available. Travel duration is 20h 6m
-
Viva Aerobus16h 35m000:15Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center14:50Tijuana AirportTijuana Airport0EconomyA Flight from Viva Aerobus goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 11/02/2026 00:15:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 11/02/2026 14:50:00. 50 Economy ticket for £167 per person are available. Travel duration is 16h 35m
-
Viva Aerobus22h 10m000:15Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center20:25Tijuana AirportTijuana Airport0EconomyA Flight from Viva Aerobus goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 11/02/2026 00:15:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 11/02/2026 20:25:00. 50 Economy ticket for £167 per person are available. Travel duration is 22h 10m
-
Aeroméxico28h 46m014:54Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center17:40Tijuana AirportTijuana Airport0EconomyA Flight from Aeroméxico goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 11/02/2026 14:54:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 12/02/2026 17:40:00. 50 Economy ticket for £211 per person are available. Travel duration is 28h 46m
-
Greyhound US58h 20m010:00ChicagoUnion Station18:20San DiegoSan Ysidro Transit Center0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 11/02/2026 10:00:00 to San Ysidro Transit Center, San Diego (USA) arriving at 13/02/2026 18:20:00. 50 Economy ticket for £221 per person are available. Travel duration is 58h 20m
-
Greyhound US52h 39m012:01ChicagoDowntown Coach Station14:40San DiegoSan Ysidro Transit Center0EconomyA Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 11/02/2026 12:01:00 to San Ysidro Transit Center, San Diego (USA) arriving at 13/02/2026 14:40:00. 50 Economy ticket for £221 per person are available. Travel duration is 52h 39m
-
Greyhound US62h 15m010:00ChicagoUnion Station22:15San DiegoSeaport Village0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 11/02/2026 10:00:00 to Seaport Village, San Diego (USA) arriving at 13/02/2026 22:15:00. 50 Economy ticket for £222 per person are available. Travel duration is 62h 15m
-
Greyhound US53h 35m014:45ChicagoDowntown Coach Station18:20San DiegoSan Ysidro Transit Center0EconomyA Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 11/02/2026 14:45:00 to San Ysidro Transit Center, San Diego (USA) arriving at 13/02/2026 18:20:00. 50 Economy ticket for £222 per person are available. Travel duration is 53h 35m
-
Greyhound US53h 0m014:45ChicagoDowntown Coach Station17:45San DiegoOld Town Transit Center0EconomyA Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 11/02/2026 14:45:00 to Old Town Transit Center, San Diego (USA) arriving at 13/02/2026 17:45:00. 50 Economy ticket for £224 per person are available. Travel duration is 53h 0m
Cheapest Flights Wednesday
Cheapest Buses Wednesday
What are the fastest trips from Chicago to San Diego?
You can get to San Diego from Chicago in just 10h 17m with a Flight from Viva Aerobus. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
-
Frontier Airlines11h 55m007:11Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center17:06Tijuana AirportTijuana Airport0EconomyA Flight from Frontier Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 05/02/2026 07:11:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 05/02/2026 17:06:00. 50 Economy ticket for £274 per person are available. Travel duration is 11h 55m
-
Aeroméxico14h 24m013:26Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center01:50Tijuana AirportTijuana Airport0EconomyA Flight from Aeroméxico goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 05/02/2026 13:26:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 06/02/2026 01:50:00. 50 Economy ticket for £240 per person are available. Travel duration is 14h 24m
-
Aeroméxico17h 46m014:54Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center06:40Tijuana AirportTijuana Airport0EconomyA Flight from Aeroméxico goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 05/02/2026 14:54:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 06/02/2026 06:40:00. 50 Economy ticket for £204 per person are available. Travel duration is 17h 46m
-
Volaris19h 2m006:23Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center23:25Tijuana AirportTijuana Airport0EconomyA Flight from Volaris goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 05/02/2026 06:23:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 05/02/2026 23:25:00. 50 Economy ticket for £138 per person are available. Travel duration is 19h 2m
-
Volaris21h 21m023:59Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center19:20Tijuana AirportTijuana Airport0EconomyA Flight from Volaris goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 05/02/2026 23:59:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 06/02/2026 19:20:00. 50 Economy ticket for £132 per person are available. Travel duration is 21h 21m
-
Greyhound US52h 50m014:45ChicagoDowntown Coach Station17:35San DiegoLa Jolla Village0EconomyA Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 05/02/2026 14:45:00 to La Jolla Village, San Diego (USA) arriving at 07/02/2026 17:35:00. 50 Economy ticket for £179 per person are available. Travel duration is 52h 50m
-
Greyhound US57h 35m010:00ChicagoUnion Station17:35San DiegoLa Jolla Village0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 05/02/2026 10:00:00 to La Jolla Village, San Diego (USA) arriving at 07/02/2026 17:35:00. 50 Economy ticket for £179 per person are available. Travel duration is 57h 35m
-
Greyhound US60h 30m023:10ChicagoUnion Station09:40San DiegoLa Jolla Village0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 05/02/2026 23:10:00 to La Jolla Village, San Diego (USA) arriving at 08/02/2026 09:40:00. 50 Economy ticket for £179 per person are available. Travel duration is 60h 30m
-
Greyhound US62h 15m010:00ChicagoUnion Station22:15San DiegoSeaport Village0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 05/02/2026 10:00:00 to Seaport Village, San Diego (USA) arriving at 07/02/2026 22:15:00. 50 Economy ticket for £180 per person are available. Travel duration is 62h 15m
-
Greyhound US62h 35m023:10ChicagoUnion Station11:45San DiegoOld Town Transit Center0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 05/02/2026 23:10:00 to Old Town Transit Center, San Diego (USA) arriving at 08/02/2026 11:45:00. 50 Economy ticket for £179 per person are available. Travel duration is 62h 35m
Fastest Flights Thursday
Fastest Buses Thursday
-
Aeroméxico18h 21m014:54Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center07:15Tijuana AirportTijuana Airport0EconomyA Flight from Aeroméxico goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 07/02/2026 14:54:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 08/02/2026 07:15:00. 50 Economy ticket for £194 per person are available. Travel duration is 18h 21m
-
Viva Aerobus23h 44m000:15Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center21:59Tijuana AirportTijuana Airport0EconomyA Flight from Viva Aerobus goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 07/02/2026 00:15:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 07/02/2026 21:59:00. 50 Economy ticket for £144 per person are available. Travel duration is 23h 44m
-
Volaris24h 0m023:59Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center21:59Tijuana AirportTijuana Airport0EconomyA Flight from Volaris goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 07/02/2026 23:59:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 08/02/2026 21:59:00. 50 Economy ticket for £139 per person are available. Travel duration is 24h 0m
-
Viva Aerobus26h 33m000:15Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center00:48Tijuana AirportTijuana Airport0EconomyA Flight from Viva Aerobus goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 07/02/2026 00:15:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 08/02/2026 00:48:00. 50 Economy ticket for £142 per person are available. Travel duration is 26h 33m
-
Volaris32h 30m023:59Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center06:29Tijuana AirportTijuana Airport0EconomyA Flight from Volaris goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 07/02/2026 23:59:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 09/02/2026 06:29:00. 50 Economy ticket for £130 per person are available. Travel duration is 32h 30m
-
FlixBus51h 50m016:30ChicagoDowntown Coach Station18:20San DiegoSan Ysidro Transit Center0EconomyA Bus from FlixBus goes from Downtown Coach Station, Chicago (USA) at 07/02/2026 16:30:00 to San Ysidro Transit Center, San Diego (USA) arriving at 09/02/2026 18:20:00. 50 Economy ticket for £236 per person are available. Travel duration is 51h 50m
-
Greyhound US52h 39m012:01ChicagoDowntown Coach Station14:40San DiegoSan Ysidro Transit Center0EconomyA Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 07/02/2026 12:01:00 to San Ysidro Transit Center, San Diego (USA) arriving at 09/02/2026 14:40:00. 50 Economy ticket for £239 per person are available. Travel duration is 52h 39m
-
Greyhound US58h 20m010:00ChicagoUnion Station18:20San DiegoSan Ysidro Transit Center0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 07/02/2026 10:00:00 to San Ysidro Transit Center, San Diego (USA) arriving at 09/02/2026 18:20:00. 50 Economy ticket for £236 per person are available. Travel duration is 58h 20m
-
Greyhound US63h 10m023:10ChicagoUnion Station12:20San DiegoSan Ysidro Transit Center0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 07/02/2026 23:10:00 to San Ysidro Transit Center, San Diego (USA) arriving at 10/02/2026 12:20:00. 50 Economy ticket for £229 per person are available. Travel duration is 63h 10m
Fastest Flights Saturday
Fastest Buses Saturday
-
Viva Aerobus10h 17m000:15Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center08:32Tijuana AirportTijuana Airport0EconomyA Flight from Viva Aerobus goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 08/02/2026 00:15:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 08/02/2026 08:32:00. 50 Economy ticket for £166 per person are available. Travel duration is 10h 17m
-
Frontier Airlines11h 55m007:11Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center17:06Tijuana AirportTijuana Airport0EconomyA Flight from Frontier Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 08/02/2026 07:11:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 08/02/2026 17:06:00. 50 Economy ticket for £240 per person are available. Travel duration is 11h 55m
-
Spirit Airlines15h 55m006:05Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center20:00Tijuana AirportTijuana Airport0EconomyA Flight from Spirit Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 08/02/2026 06:05:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 08/02/2026 20:00:00. 50 Economy ticket for £154 per person are available. Travel duration is 15h 55m
-
Aeroméxico19h 39m013:26Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center07:05Tijuana AirportTijuana Airport0EconomyA Flight from Aeroméxico goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 08/02/2026 13:26:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 09/02/2026 07:05:00. 50 Economy ticket for £205 per person are available. Travel duration is 19h 39m
-
Volaris20h 6m012:59Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center07:05Tijuana AirportTijuana Airport0EconomyA Flight from Volaris goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 08/02/2026 12:59:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 09/02/2026 07:05:00. 50 Economy ticket for £141 per person are available. Travel duration is 20h 6m
Fastest Flights Sunday
-
Frontier Airlines11h 11m007:55Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center17:06Tijuana AirportTijuana Airport0EconomyA Flight from Frontier Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 10/02/2026 07:55:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 10/02/2026 17:06:00. 50 Economy ticket for £212 per person are available. Travel duration is 11h 11m
-
Viva Aerobus11h 37m001:20Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center10:57Tijuana AirportTijuana Airport0EconomyA Flight from Viva Aerobus goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 10/02/2026 01:20:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 10/02/2026 10:57:00. 50 Economy ticket for £112 per person are available. Travel duration is 11h 37m
-
Spirit Airlines13h 1m006:05Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center17:06Tijuana AirportTijuana Airport0EconomyA Flight from Spirit Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 10/02/2026 06:05:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 10/02/2026 17:06:00. 50 Economy ticket for £126 per person are available. Travel duration is 13h 1m
-
Aeroméxico17h 46m014:54Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center06:40Tijuana AirportTijuana Airport0EconomyA Flight from Aeroméxico goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 10/02/2026 14:54:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 11/02/2026 06:40:00. 50 Economy ticket for £234 per person are available. Travel duration is 17h 46m
-
Volaris32h 21m012:59Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center19:20Tijuana AirportTijuana Airport0EconomyA Flight from Volaris goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 10/02/2026 12:59:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 11/02/2026 19:20:00. 50 Economy ticket for £114 per person are available. Travel duration is 32h 21m
-
FlixBus51h 5m016:30ChicagoDowntown Coach Station17:35San DiegoLa Jolla Village0EconomyA Bus from FlixBus goes from Downtown Coach Station, Chicago (USA) at 10/02/2026 16:30:00 to La Jolla Village, San Diego (USA) arriving at 12/02/2026 17:35:00. 50 Economy ticket for £192 per person are available. Travel duration is 51h 5m
-
Greyhound US51h 39m012:01ChicagoDowntown Coach Station13:40San DiegoLa Jolla Village0EconomyA Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 10/02/2026 12:01:00 to La Jolla Village, San Diego (USA) arriving at 12/02/2026 13:40:00. 50 Economy ticket for £192 per person are available. Travel duration is 51h 39m
-
FlixBus51h 40m016:30ChicagoDowntown Coach Station18:10San DiegoOld Town Transit Center0EconomyA Bus from FlixBus goes from Downtown Coach Station, Chicago (USA) at 10/02/2026 16:30:00 to Old Town Transit Center, San Diego (USA) arriving at 12/02/2026 18:10:00. 50 Economy ticket for £192 per person are available. Travel duration is 51h 40m
-
Greyhound US52h 9m012:01ChicagoDowntown Coach Station14:10San DiegoOld Town Transit Center0EconomyA Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 10/02/2026 12:01:00 to Old Town Transit Center, San Diego (USA) arriving at 12/02/2026 14:10:00. 50 Economy ticket for £192 per person are available. Travel duration is 52h 9m
-
Greyhound US60h 55m023:10ChicagoUnion Station10:05San DiegoSeaport Village0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 10/02/2026 23:10:00 to Seaport Village, San Diego (USA) arriving at 13/02/2026 10:05:00. 50 Economy ticket for £192 per person are available. Travel duration is 60h 55m
Fastest Flights Tuesday
Fastest Buses Tuesday
-
Volaris14h 51m012:59Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center01:50Tijuana AirportTijuana Airport0EconomyA Flight from Volaris goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 11/02/2026 12:59:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 12/02/2026 01:50:00. 50 Economy ticket for £158 per person are available. Travel duration is 14h 51m
-
Viva Aerobus16h 35m000:15Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center14:50Tijuana AirportTijuana Airport0EconomyA Flight from Viva Aerobus goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 11/02/2026 00:15:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 11/02/2026 14:50:00. 50 Economy ticket for £167 per person are available. Travel duration is 16h 35m
-
Volaris20h 6m012:59Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center07:05Tijuana AirportTijuana Airport0EconomyA Flight from Volaris goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 11/02/2026 12:59:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 12/02/2026 07:05:00. 50 Economy ticket for £164 per person are available. Travel duration is 20h 6m
-
Viva Aerobus22h 10m000:15Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center20:25Tijuana AirportTijuana Airport0EconomyA Flight from Viva Aerobus goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 11/02/2026 00:15:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 11/02/2026 20:25:00. 50 Economy ticket for £167 per person are available. Travel duration is 22h 10m
-
Aeroméxico28h 46m014:54Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center17:40Tijuana AirportTijuana Airport0EconomyA Flight from Aeroméxico goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 11/02/2026 14:54:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 12/02/2026 17:40:00. 50 Economy ticket for £211 per person are available. Travel duration is 28h 46m
-
Greyhound US52h 39m012:01ChicagoDowntown Coach Station14:40San DiegoSan Ysidro Transit Center0EconomyA Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 11/02/2026 12:01:00 to San Ysidro Transit Center, San Diego (USA) arriving at 13/02/2026 14:40:00. 50 Economy ticket for £221 per person are available. Travel duration is 52h 39m
-
Greyhound US53h 0m014:45ChicagoDowntown Coach Station17:45San DiegoOld Town Transit Center0EconomyA Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 11/02/2026 14:45:00 to Old Town Transit Center, San Diego (USA) arriving at 13/02/2026 17:45:00. 50 Economy ticket for £224 per person are available. Travel duration is 53h 0m
-
Greyhound US53h 35m014:45ChicagoDowntown Coach Station18:20San DiegoSan Ysidro Transit Center0EconomyA Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 11/02/2026 14:45:00 to San Ysidro Transit Center, San Diego (USA) arriving at 13/02/2026 18:20:00. 50 Economy ticket for £222 per person are available. Travel duration is 53h 35m
-
Greyhound US58h 20m010:00ChicagoUnion Station18:20San DiegoSan Ysidro Transit Center0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 11/02/2026 10:00:00 to San Ysidro Transit Center, San Diego (USA) arriving at 13/02/2026 18:20:00. 50 Economy ticket for £221 per person are available. Travel duration is 58h 20m
-
Greyhound US62h 15m010:00ChicagoUnion Station22:15San DiegoSeaport Village0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 11/02/2026 10:00:00 to Seaport Village, San Diego (USA) arriving at 13/02/2026 22:15:00. 50 Economy ticket for £222 per person are available. Travel duration is 62h 15m
Fastest Flights Wednesday
Fastest Buses Wednesday
Here you will find all operators and timetables for a
Bus from Chicago to San Diego
What are the most popular stations in Chicago and San Diego?
In Chicago, you will usually depart from California & 35th Street Coach Stop, Downtown Coach Station or 95th Red Line Station, while in San Diego you will be arriving at San Ysidro Transit Center, University Av & Bancroft St Coach Stop or Old Town Transit Center, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to San Diego from Chicago? With 8 connections between 2 Flight and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Chicago and San Diego, you can pay as low as £112 with a Flight from Viva Aerobus.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Viva Aerobus: you will get to San Diego in just 10h 17m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Chicago and San Diego are Greyhound US, Volaris and Aeroméxico, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Chicago and San Diego is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Cicero, IL or to San Diego Airport, and look at flights from Chicago Midway Airport, and landing at Tijuana Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Chicago to San Diego?
The most popular companies between Chicago and San Diego, are Greyhound US, Volaris and Aeroméxico. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: Greyhound US and FlixBus
Airlines: Volaris, Aeroméxico, Viva Aerobus and 2 more.
All you need to know when you travel from Chicago to San Diego
Check all information on comfort and services on all modes of transports from Chicago to San Diego. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Chicago to San Diego
How can I reach San Diego from Chicago?
Every day, there are on average 8 connections between Flight and Bus, with which you can get to San Diego from Chicago.
How far is San Diego from Chicago?
The distance between Chicago and San Diego is 2,784.7 km.
What is the most ecofriendly mode of transport between Chicago and San Diego?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 75 kgs of CO2, a train 97 kgs, a car 473 kgs, and a flight 685 kgs.
What is the cheapest mode of transport from Chicago to San Diego?
You can get to San Diego with just £112 by taking a Flight from Viva Aerobus.
What is the fastest way to get from Chicago to San Diego?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to San Diego in just 10h 17m with a Flight from Viva Aerobus.
More routes to Chicago and to San Diego
Looking for more options? Here you can see the most popular routes to Chicago and to San Diego. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Chicago
- Aguascalientes to Chicago
- Atlanta, GA to Chicago
- Bloomington, IN to Chicago
- Buffalo, NY to Chicago
- Cincinnati to Chicago
- Dallas to Chicago
- El Paso, TX to Chicago
- Houston to Chicago
- Los Angeles to Chicago
- Louisville, KY to Chicago
- Memphis to Chicago
- Mexico City to Chicago
- Monterrey, NL to Chicago
- Nashville to Chicago
- New York to Chicago
- Pearson Toronto Airport to Chicago
- Phoenix, AZ to Chicago
- San Antonio, TX to Chicago
- Santiago de Queretaro to Chicago
- St. Louis, MO to Chicago
- Toronto, ON to Chicago
- Tulsa to Chicago
- Trips to San Diego
- Bakersfield, CA to San Diego
- El Paso, TX to San Diego
- Houston to San Diego
- Las Vegas to San Diego
- Mexico City to San Diego
- New York to San Diego
- Pasco, WA to San Diego
- Phoenix, AZ to San Diego
- Salt Lake City, UT to San Diego
- San Francisco to San Diego
- San Jose, CA to San Diego
- Yakima, WA to San Diego
