What is the best way to travel from Chicago to San Diego?
Looking for a trip? Check and compare all the available Flights and Buses to San Diego from Chicago. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 2 available companies to find your perfect trip!
What is the cheapest way to reach San Diego from Chicago?
You can reach San Diego with just £83 by taking a Flight from Frontier Airlines, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
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Alaska Airlines4h 40m014:21Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center17:01San Diego AirportSan Diego Airport0EconomyA Flight from Alaska Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 16/10/2026 14:21:00 to San Diego Airport, San Diego Airport (USA) arriving at 16/10/2026 17:01:00. 50 Economy ticket for £111 per person are available. Travel duration is 4h 40m
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United Airlines4h 25m020:16Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center22:41San Diego AirportSan Diego Airport0EconomyA Flight from United Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 16/10/2026 20:16:00 to San Diego Airport, San Diego Airport (USA) arriving at 16/10/2026 22:41:00. 50 Economy ticket for £111 per person are available. Travel duration is 4h 25m
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Frontier Airlines27h 19m015:30Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center16:49San Diego AirportSan Diego Airport0EconomyA Flight from Frontier Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 16/10/2026 15:30:00 to San Diego Airport, San Diego Airport (USA) arriving at 17/10/2026 16:49:00. 50 Economy ticket for £130 per person are available. Travel duration is 27h 19m
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Allegiant Air26h 19m016:30Chicago Midway AirportChicago Midway Airport16:49San Diego AirportSan Diego Airport0EconomyA Flight from Allegiant Air goes from Chicago Midway Airport, Chicago Midway Airport (USA) at 16/10/2026 16:30:00 to San Diego Airport, San Diego Airport (USA) arriving at 17/10/2026 16:49:00. 50 Economy ticket for £239 per person are available. Travel duration is 26h 19m
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American Airlines10h 45m011:35Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center20:20San Diego AirportSan Diego Airport0EconomyA Flight from American Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 16/10/2026 11:35:00 to San Diego Airport, San Diego Airport (USA) arriving at 16/10/2026 20:20:00. 50 Economy ticket for £261 per person are available. Travel duration is 10h 45m
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United Airlines10h 20m012:40Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center21:00McClellan-Palomar AirportMcClellan-Palomar Airport0EconomyA Flight from United Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 16/10/2026 12:40:00 to McClellan-Palomar Airport, McClellan-Palomar Airport (USA) arriving at 16/10/2026 21:00:00. 50 Economy ticket for £283 per person are available. Travel duration is 10h 20m
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FlixBus61h 40m023:55Chicago95th Red Line Station11:35San DiegoOld Town Transit Center0EconomyA Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 16/10/2026 23:55:00 to Old Town Transit Center, San Diego (USA) arriving at 19/10/2026 11:35:00. 50 Economy ticket for £126 per person are available. Travel duration is 61h 40m
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Greyhound US54h 25m013:20Chicago95th Red Line Station17:45San DiegoOld Town Transit Center0EconomyA Bus from Greyhound US goes from 95th Red Line Station, Chicago (USA) at 16/10/2026 13:20:00 to Old Town Transit Center, San Diego (USA) arriving at 18/10/2026 17:45:00. 50 Economy ticket for £127 per person are available. Travel duration is 54h 25m
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FlixBus62h 0m023:55Chicago95th Red Line Station11:55San DiegoSeaport Village0EconomyA Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 16/10/2026 23:55:00 to Seaport Village, San Diego (USA) arriving at 19/10/2026 11:55:00. 50 Economy ticket for £127 per person are available. Travel duration is 62h 0m
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FlixBus50h 30m011:05Chicago95th Red Line Station11:35San DiegoOld Town Transit Center0EconomyA Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 16/10/2026 11:05:00 to Old Town Transit Center, San Diego (USA) arriving at 18/10/2026 11:35:00. 50 Economy ticket for £129 per person are available. Travel duration is 50h 30m
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Greyhound US58h 55m013:20Chicago95th Red Line Station22:15San DiegoSeaport Village0EconomyA Bus from Greyhound US goes from 95th Red Line Station, Chicago (USA) at 16/10/2026 13:20:00 to Seaport Village, San Diego (USA) arriving at 18/10/2026 22:15:00. 50 Economy ticket for £130 per person are available. Travel duration is 58h 55m
Cheapest Flights Friday
Cheapest Buses Friday
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Frontier Airlines11h 28m006:30Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center15:58San Diego AirportSan Diego Airport0EconomyA Flight from Frontier Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 17/10/2026 06:30:00 to San Diego Airport, San Diego Airport (USA) arriving at 17/10/2026 15:58:00. 50 Economy ticket for £85 per person are available. Travel duration is 11h 28m
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United Airlines4h 30m016:10Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center18:40San Diego AirportSan Diego Airport0EconomyA Flight from United Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 17/10/2026 16:10:00 to San Diego Airport, San Diego Airport (USA) arriving at 17/10/2026 18:40:00. 50 Economy ticket for £86 per person are available. Travel duration is 4h 30m
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Alaska Airlines4h 36m007:20Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center09:56San Diego AirportSan Diego Airport0EconomyA Flight from Alaska Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 17/10/2026 07:20:00 to San Diego Airport, San Diego Airport (USA) arriving at 17/10/2026 09:56:00. 50 Economy ticket for £86 per person are available. Travel duration is 4h 36m
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Volaris12h 39m013:49Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center00:28Tijuana AirportTijuana Airport0EconomyA Flight from Volaris goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 17/10/2026 13:49:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 18/10/2026 00:28:00. 50 Economy ticket for £119 per person are available. Travel duration is 12h 39m
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Viva Aerobus43h 45m014:40Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center08:25Tijuana AirportTijuana Airport0EconomyA Flight from Viva Aerobus goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 17/10/2026 14:40:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 19/10/2026 08:25:00. 50 Economy ticket for £182 per person are available. Travel duration is 43h 45m
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JetBlue Airways16h 5m020:04Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center10:09San Diego AirportSan Diego Airport0EconomyA Flight from JetBlue Airways goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 17/10/2026 20:04:00 to San Diego Airport, San Diego Airport (USA) arriving at 18/10/2026 10:09:00. 50 Economy ticket for £224 per person are available. Travel duration is 16h 5m
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Greyhound US57h 30m010:15ChicagoCanal & Van Buren17:45San DiegoOld Town Transit Center0EconomyA Bus from Greyhound US goes from Canal & Van Buren, Chicago (USA) at 17/10/2026 10:15:00 to Old Town Transit Center, San Diego (USA) arriving at 19/10/2026 17:45:00. 50 Economy ticket for £121 per person are available. Travel duration is 57h 30m
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FlixBus50h 50m011:05Chicago95th Red Line Station11:55San DiegoSeaport Village0EconomyA Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 17/10/2026 11:05:00 to Seaport Village, San Diego (USA) arriving at 19/10/2026 11:55:00. 50 Economy ticket for £122 per person are available. Travel duration is 50h 50m
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Greyhound US62h 0m010:15ChicagoCanal & Van Buren22:15San DiegoSeaport Village0EconomyA Bus from Greyhound US goes from Canal & Van Buren, Chicago (USA) at 17/10/2026 10:15:00 to Seaport Village, San Diego (USA) arriving at 19/10/2026 22:15:00. 50 Economy ticket for £122 per person are available. Travel duration is 62h 0m
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FlixBus61h 5m000:40Chicago95th Red Line Station11:45San DiegoOld Town Transit Center0EconomyA Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 17/10/2026 00:40:00 to Old Town Transit Center, San Diego (USA) arriving at 19/10/2026 11:45:00. 50 Economy ticket for £123 per person are available. Travel duration is 61h 5m
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FlixBus50h 30m011:05Chicago95th Red Line Station11:35San DiegoOld Town Transit Center0EconomyA Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 17/10/2026 11:05:00 to Old Town Transit Center, San Diego (USA) arriving at 19/10/2026 11:35:00. 50 Economy ticket for £123 per person are available. Travel duration is 50h 30m
Cheapest Flights Saturday
Cheapest Buses Saturday
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FlixBus61h 40m023:55Chicago95th Red Line Station11:35San DiegoOld Town Transit Center0EconomyA Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 18/10/2026 23:55:00 to Old Town Transit Center, San Diego (USA) arriving at 21/10/2026 11:35:00. 50 Economy ticket for £117 per person are available. Travel duration is 61h 40m
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FlixBus69h 10m023:55Chicago95th Red Line Station19:05San DiegoOld Town Transit Center0EconomyA Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 18/10/2026 23:55:00 to Old Town Transit Center, San Diego (USA) arriving at 21/10/2026 19:05:00. 50 Economy ticket for £117 per person are available. Travel duration is 69h 10m
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FlixBus62h 0m023:55Chicago95th Red Line Station11:55San DiegoSeaport Village0EconomyA Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 18/10/2026 23:55:00 to Seaport Village, San Diego (USA) arriving at 21/10/2026 11:55:00. 50 Economy ticket for £117 per person are available. Travel duration is 62h 0m
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Greyhound US49h 30m012:25ChicagoDowntown Coach Station11:55San DiegoSeaport Village0EconomyA Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 18/10/2026 12:25:00 to Seaport Village, San Diego (USA) arriving at 20/10/2026 11:55:00. 50 Economy ticket for £123 per person are available. Travel duration is 49h 30m
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Greyhound US54h 25m013:20Chicago95th Red Line Station17:45San DiegoOld Town Transit Center0EconomyA Bus from Greyhound US goes from 95th Red Line Station, Chicago (USA) at 18/10/2026 13:20:00 to Old Town Transit Center, San Diego (USA) arriving at 20/10/2026 17:45:00. 50 Economy ticket for £124 per person are available. Travel duration is 54h 25m
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Alaska Airlines4h 36m007:20Chicago Midway AirportChicago Midway Airport09:56San Diego AirportSan Diego Airport0EconomyA Flight from Alaska Airlines goes from Chicago Midway Airport, Chicago Midway Airport (USA) at 18/10/2026 07:20:00 to San Diego Airport, San Diego Airport (USA) arriving at 18/10/2026 09:56:00. 50 Economy ticket for £127 per person are available. Travel duration is 4h 36m
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Alaska Airlines4h 36m007:20Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center09:56San Diego AirportSan Diego Airport0EconomyA Flight from Alaska Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 18/10/2026 07:20:00 to San Diego Airport, San Diego Airport (USA) arriving at 18/10/2026 09:56:00. 50 Economy ticket for £127 per person are available. Travel duration is 4h 36m
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Frontier Airlines32h 52m006:24Chicago Midway AirportChicago Midway Airport13:16San Diego AirportSan Diego Airport0EconomyA Flight from Frontier Airlines goes from Chicago Midway Airport, Chicago Midway Airport (USA) at 18/10/2026 06:24:00 to San Diego Airport, San Diego Airport (USA) arriving at 19/10/2026 13:16:00. 50 Economy ticket for £192 per person are available. Travel duration is 32h 52m
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Frontier Airlines39h 25m006:24Chicago Midway AirportChicago Midway Airport19:49San Diego AirportSan Diego Airport0EconomyA Flight from Frontier Airlines goes from Chicago Midway Airport, Chicago Midway Airport (USA) at 18/10/2026 06:24:00 to San Diego Airport, San Diego Airport (USA) arriving at 19/10/2026 19:49:00. 50 Economy ticket for £193 per person are available. Travel duration is 39h 25m
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Volaris29h 51m020:23Chicago Midway AirportChicago Midway Airport00:14Tijuana AirportTijuana Airport0EconomyA Flight from Volaris goes from Chicago Midway Airport, Chicago Midway Airport (USA) at 18/10/2026 20:23:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 20/10/2026 00:14:00. 50 Economy ticket for £210 per person are available. Travel duration is 29h 51m
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Volaris28h 16m020:23Chicago Midway AirportChicago Midway Airport22:39Tijuana AirportTijuana Airport0EconomyA Flight from Volaris goes from Chicago Midway Airport, Chicago Midway Airport (USA) at 18/10/2026 20:23:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 19/10/2026 22:39:00. 50 Economy ticket for £222 per person are available. Travel duration is 28h 16m
Cheapest Buses Sunday
Cheapest Flights Sunday
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FlixBus61h 5m000:40Chicago95th Red Line Station11:45San DiegoOld Town Transit Center0EconomyA Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 19/10/2026 00:40:00 to Old Town Transit Center, San Diego (USA) arriving at 21/10/2026 11:45:00. 50 Economy ticket for £114 per person are available. Travel duration is 61h 5m
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FlixBus50h 30m011:05Chicago95th Red Line Station11:35San DiegoOld Town Transit Center0EconomyA Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 19/10/2026 11:05:00 to Old Town Transit Center, San Diego (USA) arriving at 21/10/2026 11:35:00. 50 Economy ticket for £114 per person are available. Travel duration is 50h 30m
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FlixBus69h 10m023:55Chicago95th Red Line Station19:05San DiegoOld Town Transit Center0EconomyA Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 19/10/2026 23:55:00 to Old Town Transit Center, San Diego (USA) arriving at 22/10/2026 19:05:00. 50 Economy ticket for £114 per person are available. Travel duration is 69h 10m
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Greyhound US49h 30m012:25ChicagoDowntown Coach Station11:55San DiegoSeaport Village0EconomyA Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 19/10/2026 12:25:00 to Seaport Village, San Diego (USA) arriving at 21/10/2026 11:55:00. 50 Economy ticket for £114 per person are available. Travel duration is 49h 30m
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Greyhound US49h 10m012:25ChicagoDowntown Coach Station11:35San DiegoOld Town Transit Center0EconomyA Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 19/10/2026 12:25:00 to Old Town Transit Center, San Diego (USA) arriving at 21/10/2026 11:35:00. 50 Economy ticket for £115 per person are available. Travel duration is 49h 10m
Cheapest Buses Monday
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Frontier Airlines11h 28m006:30Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center15:58San Diego AirportSan Diego Airport0EconomyA Flight from Frontier Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 20/10/2026 06:30:00 to San Diego Airport, San Diego Airport (USA) arriving at 20/10/2026 15:58:00. 50 Economy ticket for £83 per person are available. Travel duration is 11h 28m
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United Airlines4h 27m007:05Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center09:32San Diego AirportSan Diego Airport0EconomyA Flight from United Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 20/10/2026 07:05:00 to San Diego Airport, San Diego Airport (USA) arriving at 20/10/2026 09:32:00. 50 Economy ticket for £96 per person are available. Travel duration is 4h 27m
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Alaska Airlines4h 36m007:20Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center09:56San Diego AirportSan Diego Airport0EconomyA Flight from Alaska Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 20/10/2026 07:20:00 to San Diego Airport, San Diego Airport (USA) arriving at 20/10/2026 09:56:00. 50 Economy ticket for £96 per person are available. Travel duration is 4h 36m
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United Airlines8h 0m006:07Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center12:07McClellan-Palomar AirportMcClellan-Palomar Airport0EconomyA Flight from United Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 20/10/2026 06:07:00 to McClellan-Palomar Airport, McClellan-Palomar Airport (USA) arriving at 20/10/2026 12:07:00. 50 Economy ticket for £285 per person are available. Travel duration is 8h 0m
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United Airlines7h 55m007:00Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center12:55McClellan-Palomar AirportMcClellan-Palomar Airport0EconomyA Flight from United Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 20/10/2026 07:00:00 to McClellan-Palomar Airport, McClellan-Palomar Airport (USA) arriving at 20/10/2026 12:55:00. 50 Economy ticket for £286 per person are available. Travel duration is 7h 55m
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United Airlines8h 8m014:30Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center20:38McClellan-Palomar AirportMcClellan-Palomar Airport0EconomyA Flight from United Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 20/10/2026 14:30:00 to McClellan-Palomar Airport, McClellan-Palomar Airport (USA) arriving at 20/10/2026 20:38:00. 50 Economy ticket for £286 per person are available. Travel duration is 8h 8m
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Greyhound US49h 10m012:25ChicagoDowntown Coach Station11:35San DiegoOld Town Transit Center0EconomyA Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 20/10/2026 12:25:00 to Old Town Transit Center, San Diego (USA) arriving at 22/10/2026 11:35:00. 50 Economy ticket for £117 per person are available. Travel duration is 49h 10m
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Greyhound US48h 50m012:25ChicagoDowntown Coach Station11:15San DiegoLa Jolla Village0EconomyA Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 20/10/2026 12:25:00 to La Jolla Village, San Diego (USA) arriving at 22/10/2026 11:15:00. 50 Economy ticket for £117 per person are available. Travel duration is 48h 50m
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Greyhound US49h 30m012:25ChicagoDowntown Coach Station11:55San DiegoSeaport Village0EconomyA Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 20/10/2026 12:25:00 to Seaport Village, San Diego (USA) arriving at 22/10/2026 11:55:00. 50 Economy ticket for £118 per person are available. Travel duration is 49h 30m
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FlixBus57h 15m011:05Chicago95th Red Line Station18:20San DiegoSan Ysidro Transit Center0EconomyA Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 20/10/2026 11:05:00 to San Ysidro Transit Center, San Diego (USA) arriving at 22/10/2026 18:20:00. 50 Economy ticket for £162 per person are available. Travel duration is 57h 15m
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FlixBus74h 35m016:35Chicago95th Red Line Station17:10San DiegoSan Ysidro Transit Center0EconomyA Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 20/10/2026 16:35:00 to San Ysidro Transit Center, San Diego (USA) arriving at 23/10/2026 17:10:00. 50 Economy ticket for £179 per person are available. Travel duration is 74h 35m
Cheapest Flights Tuesday
Cheapest Buses Tuesday
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Greyhound US66h 40m023:45Chicago95th Red Line Station16:25San DiegoOld Town Transit Center0EconomyA Bus from Greyhound US goes from 95th Red Line Station, Chicago (USA) at 21/10/2026 23:45:00 to Old Town Transit Center, San Diego (USA) arriving at 24/10/2026 16:25:00. 50 Economy ticket for £101 per person are available. Travel duration is 66h 40m
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FlixBus55h 20m011:05Chicago95th Red Line Station16:25San DiegoOld Town Transit Center0EconomyA Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 21/10/2026 11:05:00 to Old Town Transit Center, San Diego (USA) arriving at 23/10/2026 16:25:00. 50 Economy ticket for £101 per person are available. Travel duration is 55h 20m
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Greyhound US62h 0m023:45Chicago95th Red Line Station11:45San DiegoOld Town Transit Center0EconomyA Bus from Greyhound US goes from 95th Red Line Station, Chicago (USA) at 21/10/2026 23:45:00 to Old Town Transit Center, San Diego (USA) arriving at 24/10/2026 11:45:00. 50 Economy ticket for £105 per person are available. Travel duration is 62h 0m
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Greyhound US60h 20m023:45Chicago95th Red Line Station10:05San DiegoSeaport Village0EconomyA Bus from Greyhound US goes from 95th Red Line Station, Chicago (USA) at 21/10/2026 23:45:00 to Seaport Village, San Diego (USA) arriving at 24/10/2026 10:05:00. 50 Economy ticket for £105 per person are available. Travel duration is 60h 20m
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United Airlines8h 0m006:07Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center12:07McClellan-Palomar AirportMcClellan-Palomar Airport0EconomyA Flight from United Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 21/10/2026 06:07:00 to McClellan-Palomar Airport, McClellan-Palomar Airport (USA) arriving at 21/10/2026 12:07:00. 50 Economy ticket for £285 per person are available. Travel duration is 8h 0m
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United Airlines6h 15m008:40Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center12:55McClellan-Palomar AirportMcClellan-Palomar Airport0EconomyA Flight from United Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 21/10/2026 08:40:00 to McClellan-Palomar Airport, McClellan-Palomar Airport (USA) arriving at 21/10/2026 12:55:00. 50 Economy ticket for £285 per person are available. Travel duration is 6h 15m
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United Airlines7h 35m012:40Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center18:15McClellan-Palomar AirportMcClellan-Palomar Airport0EconomyA Flight from United Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 21/10/2026 12:40:00 to McClellan-Palomar Airport, McClellan-Palomar Airport (USA) arriving at 21/10/2026 18:15:00. 50 Economy ticket for £285 per person are available. Travel duration is 7h 35m
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United Airlines6h 18m016:20Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center20:38McClellan-Palomar AirportMcClellan-Palomar Airport0EconomyA Flight from United Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 21/10/2026 16:20:00 to McClellan-Palomar Airport, McClellan-Palomar Airport (USA) arriving at 21/10/2026 20:38:00. 50 Economy ticket for £285 per person are available. Travel duration is 6h 18m
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United Airlines8h 55m006:00Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center12:55McClellan-Palomar AirportMcClellan-Palomar Airport0EconomyA Flight from United Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 21/10/2026 06:00:00 to McClellan-Palomar Airport, McClellan-Palomar Airport (USA) arriving at 21/10/2026 12:55:00. 50 Economy ticket for £286 per person are available. Travel duration is 8h 55m
Cheapest Buses Wednesday
Cheapest Flights Wednesday
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Volaris13h 2m005:55Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center16:57Tijuana AirportTijuana Airport0EconomyA Flight from Volaris goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 22/10/2026 05:55:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 22/10/2026 16:57:00. 50 Economy ticket for £117 per person are available. Travel duration is 13h 2m
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Viva Aerobus24h 26m001:30Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center23:56Tijuana AirportTijuana Airport0EconomyA Flight from Viva Aerobus goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 22/10/2026 01:30:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 22/10/2026 23:56:00. 50 Economy ticket for £248 per person are available. Travel duration is 24h 26m
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Aeroméxico11h 45m001:54Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center11:39Tijuana AirportTijuana Airport0EconomyA Flight from Aeroméxico goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 22/10/2026 01:54:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 22/10/2026 11:39:00. 50 Economy ticket for £267 per person are available. Travel duration is 11h 45m
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Frontier Airlines30h 30m019:44Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center00:14Tijuana AirportTijuana Airport0EconomyA Flight from Frontier Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 22/10/2026 19:44:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 24/10/2026 00:14:00. 50 Economy ticket for £281 per person are available. Travel duration is 30h 30m
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Alaska Airlines20h 58m017:46Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center12:44Tijuana AirportTijuana Airport0EconomyA Flight from Alaska Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 22/10/2026 17:46:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 23/10/2026 12:44:00. 50 Economy ticket for £497 per person are available. Travel duration is 20h 58m
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Greyhound US55h 55m012:25ChicagoDowntown Coach Station18:20San DiegoSan Ysidro Transit Center0EconomyA Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 22/10/2026 12:25:00 to San Ysidro Transit Center, San Diego (USA) arriving at 24/10/2026 18:20:00. 50 Economy ticket for £135 per person are available. Travel duration is 55h 55m
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FlixBus51h 15m017:05ChicagoDowntown Coach Station18:20San DiegoSan Ysidro Transit Center0EconomyA Bus from FlixBus goes from Downtown Coach Station, Chicago (USA) at 22/10/2026 17:05:00 to San Ysidro Transit Center, San Diego (USA) arriving at 24/10/2026 18:20:00. 50 Economy ticket for £136 per person are available. Travel duration is 51h 15m
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Greyhound US58h 5m010:15ChicagoUnion Station18:20San DiegoSan Ysidro Transit Center0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 22/10/2026 10:15:00 to San Ysidro Transit Center, San Diego (USA) arriving at 24/10/2026 18:20:00. 50 Economy ticket for £136 per person are available. Travel duration is 58h 5m
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Greyhound US49h 35m012:25ChicagoDowntown Coach Station12:00San DiegoSan Ysidro Transit Center0EconomyA Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 22/10/2026 12:25:00 to San Ysidro Transit Center, San Diego (USA) arriving at 24/10/2026 12:00:00. 50 Economy ticket for £144 per person are available. Travel duration is 49h 35m
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FlixBus57h 15m011:05Chicago95th Red Line Station18:20San DiegoSan Ysidro Transit Center0EconomyA Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 22/10/2026 11:05:00 to San Ysidro Transit Center, San Diego (USA) arriving at 24/10/2026 18:20:00. 50 Economy ticket for £165 per person are available. Travel duration is 57h 15m
Cheapest Flights Thursday
Cheapest Buses Thursday
What are the fastest trips from Chicago to San Diego?
You can get to San Diego from Chicago in just 4h 25m with a Flight from United Airlines. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
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United Airlines4h 25m020:16Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center22:41San Diego AirportSan Diego Airport0EconomyA Flight from United Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 16/10/2026 20:16:00 to San Diego Airport, San Diego Airport (USA) arriving at 16/10/2026 22:41:00. 50 Economy ticket for £111 per person are available. Travel duration is 4h 25m
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Alaska Airlines4h 40m014:21Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center17:01San Diego AirportSan Diego Airport0EconomyA Flight from Alaska Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 16/10/2026 14:21:00 to San Diego Airport, San Diego Airport (USA) arriving at 16/10/2026 17:01:00. 50 Economy ticket for £111 per person are available. Travel duration is 4h 40m
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United Airlines6h 48m015:50Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center20:38McClellan-Palomar AirportMcClellan-Palomar Airport0EconomyA Flight from United Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 16/10/2026 15:50:00 to McClellan-Palomar Airport, McClellan-Palomar Airport (USA) arriving at 16/10/2026 20:38:00. 50 Economy ticket for £284 per person are available. Travel duration is 6h 48m
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United Airlines7h 25m015:35Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center21:00McClellan-Palomar AirportMcClellan-Palomar Airport0EconomyA Flight from United Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 16/10/2026 15:35:00 to McClellan-Palomar Airport, McClellan-Palomar Airport (USA) arriving at 16/10/2026 21:00:00. 50 Economy ticket for £284 per person are available. Travel duration is 7h 25m
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United Airlines8h 8m014:30Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center20:38McClellan-Palomar AirportMcClellan-Palomar Airport0EconomyA Flight from United Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 16/10/2026 14:30:00 to McClellan-Palomar Airport, McClellan-Palomar Airport (USA) arriving at 16/10/2026 20:38:00. 50 Economy ticket for £283 per person are available. Travel duration is 8h 8m
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United Airlines8h 28m014:32Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center21:00McClellan-Palomar AirportMcClellan-Palomar Airport0EconomyA Flight from United Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 16/10/2026 14:32:00 to McClellan-Palomar Airport, McClellan-Palomar Airport (USA) arriving at 16/10/2026 21:00:00. 50 Economy ticket for £283 per person are available. Travel duration is 8h 28m
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FlixBus50h 30m011:05Chicago95th Red Line Station11:35San DiegoOld Town Transit Center0EconomyA Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 16/10/2026 11:05:00 to Old Town Transit Center, San Diego (USA) arriving at 18/10/2026 11:35:00. 50 Economy ticket for £129 per person are available. Travel duration is 50h 30m
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Greyhound US54h 25m013:20Chicago95th Red Line Station17:45San DiegoOld Town Transit Center0EconomyA Bus from Greyhound US goes from 95th Red Line Station, Chicago (USA) at 16/10/2026 13:20:00 to Old Town Transit Center, San Diego (USA) arriving at 18/10/2026 17:45:00. 50 Economy ticket for £127 per person are available. Travel duration is 54h 25m
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Greyhound US58h 55m013:20Chicago95th Red Line Station22:15San DiegoSeaport Village0EconomyA Bus from Greyhound US goes from 95th Red Line Station, Chicago (USA) at 16/10/2026 13:20:00 to Seaport Village, San Diego (USA) arriving at 18/10/2026 22:15:00. 50 Economy ticket for £130 per person are available. Travel duration is 58h 55m
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FlixBus61h 40m023:55Chicago95th Red Line Station11:35San DiegoOld Town Transit Center0EconomyA Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 16/10/2026 23:55:00 to Old Town Transit Center, San Diego (USA) arriving at 19/10/2026 11:35:00. 50 Economy ticket for £126 per person are available. Travel duration is 61h 40m
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FlixBus62h 0m023:55Chicago95th Red Line Station11:55San DiegoSeaport Village0EconomyA Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 16/10/2026 23:55:00 to Seaport Village, San Diego (USA) arriving at 19/10/2026 11:55:00. 50 Economy ticket for £127 per person are available. Travel duration is 62h 0m
Fastest Flights Friday
Fastest Buses Friday
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United Airlines4h 30m016:10Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center18:40San Diego AirportSan Diego Airport0EconomyA Flight from United Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 17/10/2026 16:10:00 to San Diego Airport, San Diego Airport (USA) arriving at 17/10/2026 18:40:00. 50 Economy ticket for £86 per person are available. Travel duration is 4h 30m
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Alaska Airlines4h 36m007:20Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center09:56San Diego AirportSan Diego Airport0EconomyA Flight from Alaska Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 17/10/2026 07:20:00 to San Diego Airport, San Diego Airport (USA) arriving at 17/10/2026 09:56:00. 50 Economy ticket for £86 per person are available. Travel duration is 4h 36m
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Frontier Airlines11h 28m006:30Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center15:58San Diego AirportSan Diego Airport0EconomyA Flight from Frontier Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 17/10/2026 06:30:00 to San Diego Airport, San Diego Airport (USA) arriving at 17/10/2026 15:58:00. 50 Economy ticket for £85 per person are available. Travel duration is 11h 28m
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Aeroméxico11h 45m001:54Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center11:39Tijuana AirportTijuana Airport0EconomyA Flight from Aeroméxico goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 17/10/2026 01:54:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 17/10/2026 11:39:00. 50 Economy ticket for £277 per person are available. Travel duration is 11h 45m
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American Airlines12h 23m011:35Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center21:58San Diego AirportSan Diego Airport0EconomyA Flight from American Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 17/10/2026 11:35:00 to San Diego Airport, San Diego Airport (USA) arriving at 17/10/2026 21:58:00. 50 Economy ticket for £261 per person are available. Travel duration is 12h 23m
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Volaris12h 39m013:49Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center00:28Tijuana AirportTijuana Airport0EconomyA Flight from Volaris goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 17/10/2026 13:49:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 18/10/2026 00:28:00. 50 Economy ticket for £119 per person are available. Travel duration is 12h 39m
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FlixBus50h 30m011:05Chicago95th Red Line Station11:35San DiegoOld Town Transit Center0EconomyA Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 17/10/2026 11:05:00 to Old Town Transit Center, San Diego (USA) arriving at 19/10/2026 11:35:00. 50 Economy ticket for £123 per person are available. Travel duration is 50h 30m
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FlixBus50h 50m011:05Chicago95th Red Line Station11:55San DiegoSeaport Village0EconomyA Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 17/10/2026 11:05:00 to Seaport Village, San Diego (USA) arriving at 19/10/2026 11:55:00. 50 Economy ticket for £122 per person are available. Travel duration is 50h 50m
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Greyhound US57h 30m010:15ChicagoCanal & Van Buren17:45San DiegoOld Town Transit Center0EconomyA Bus from Greyhound US goes from Canal & Van Buren, Chicago (USA) at 17/10/2026 10:15:00 to Old Town Transit Center, San Diego (USA) arriving at 19/10/2026 17:45:00. 50 Economy ticket for £121 per person are available. Travel duration is 57h 30m
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FlixBus61h 5m000:40Chicago95th Red Line Station11:45San DiegoOld Town Transit Center0EconomyA Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 17/10/2026 00:40:00 to Old Town Transit Center, San Diego (USA) arriving at 19/10/2026 11:45:00. 50 Economy ticket for £123 per person are available. Travel duration is 61h 5m
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Greyhound US62h 0m010:15ChicagoCanal & Van Buren22:15San DiegoSeaport Village0EconomyA Bus from Greyhound US goes from Canal & Van Buren, Chicago (USA) at 17/10/2026 10:15:00 to Seaport Village, San Diego (USA) arriving at 19/10/2026 22:15:00. 50 Economy ticket for £122 per person are available. Travel duration is 62h 0m
Fastest Flights Saturday
Fastest Buses Saturday
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Alaska Airlines4h 36m007:20Chicago Midway AirportChicago Midway Airport09:56San Diego AirportSan Diego Airport0EconomyA Flight from Alaska Airlines goes from Chicago Midway Airport, Chicago Midway Airport (USA) at 18/10/2026 07:20:00 to San Diego Airport, San Diego Airport (USA) arriving at 18/10/2026 09:56:00. 50 Economy ticket for £127 per person are available. Travel duration is 4h 36m
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Alaska Airlines4h 36m007:20Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center09:56San Diego AirportSan Diego Airport0EconomyA Flight from Alaska Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 18/10/2026 07:20:00 to San Diego Airport, San Diego Airport (USA) arriving at 18/10/2026 09:56:00. 50 Economy ticket for £127 per person are available. Travel duration is 4h 36m
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Volaris23h 7m020:23Chicago Midway AirportChicago Midway Airport17:30Tijuana AirportTijuana Airport0EconomyA Flight from Volaris goes from Chicago Midway Airport, Chicago Midway Airport (USA) at 18/10/2026 20:23:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 19/10/2026 17:30:00. 50 Economy ticket for £225 per person are available. Travel duration is 23h 7m
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Frontier Airlines26h 29m006:24Chicago Midway AirportChicago Midway Airport06:53Tijuana AirportTijuana Airport0EconomyA Flight from Frontier Airlines goes from Chicago Midway Airport, Chicago Midway Airport (USA) at 18/10/2026 06:24:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 19/10/2026 06:53:00. 50 Economy ticket for £232 per person are available. Travel duration is 26h 29m
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Frontier Airlines27h 34m006:24Chicago Midway AirportChicago Midway Airport07:58Tijuana AirportTijuana Airport0EconomyA Flight from Frontier Airlines goes from Chicago Midway Airport, Chicago Midway Airport (USA) at 18/10/2026 06:24:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 19/10/2026 07:58:00. 50 Economy ticket for £238 per person are available. Travel duration is 27h 34m
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Volaris28h 16m020:23Chicago Midway AirportChicago Midway Airport22:39Tijuana AirportTijuana Airport0EconomyA Flight from Volaris goes from Chicago Midway Airport, Chicago Midway Airport (USA) at 18/10/2026 20:23:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 19/10/2026 22:39:00. 50 Economy ticket for £222 per person are available. Travel duration is 28h 16m
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Greyhound US49h 30m012:25ChicagoDowntown Coach Station11:55San DiegoSeaport Village0EconomyA Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 18/10/2026 12:25:00 to Seaport Village, San Diego (USA) arriving at 20/10/2026 11:55:00. 50 Economy ticket for £123 per person are available. Travel duration is 49h 30m
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Greyhound US54h 25m013:20Chicago95th Red Line Station17:45San DiegoOld Town Transit Center0EconomyA Bus from Greyhound US goes from 95th Red Line Station, Chicago (USA) at 18/10/2026 13:20:00 to Old Town Transit Center, San Diego (USA) arriving at 20/10/2026 17:45:00. 50 Economy ticket for £124 per person are available. Travel duration is 54h 25m
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FlixBus61h 40m023:55Chicago95th Red Line Station11:35San DiegoOld Town Transit Center0EconomyA Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 18/10/2026 23:55:00 to Old Town Transit Center, San Diego (USA) arriving at 21/10/2026 11:35:00. 50 Economy ticket for £117 per person are available. Travel duration is 61h 40m
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FlixBus62h 0m023:55Chicago95th Red Line Station11:55San DiegoSeaport Village0EconomyA Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 18/10/2026 23:55:00 to Seaport Village, San Diego (USA) arriving at 21/10/2026 11:55:00. 50 Economy ticket for £117 per person are available. Travel duration is 62h 0m
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FlixBus69h 10m023:55Chicago95th Red Line Station19:05San DiegoOld Town Transit Center0EconomyA Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 18/10/2026 23:55:00 to Old Town Transit Center, San Diego (USA) arriving at 21/10/2026 19:05:00. 50 Economy ticket for £117 per person are available. Travel duration is 69h 10m
Fastest Flights Sunday
Fastest Buses Sunday
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Greyhound US49h 10m012:25ChicagoDowntown Coach Station11:35San DiegoOld Town Transit Center0EconomyA Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 19/10/2026 12:25:00 to Old Town Transit Center, San Diego (USA) arriving at 21/10/2026 11:35:00. 50 Economy ticket for £115 per person are available. Travel duration is 49h 10m
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Greyhound US49h 30m012:25ChicagoDowntown Coach Station11:55San DiegoSeaport Village0EconomyA Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 19/10/2026 12:25:00 to Seaport Village, San Diego (USA) arriving at 21/10/2026 11:55:00. 50 Economy ticket for £114 per person are available. Travel duration is 49h 30m
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FlixBus50h 30m011:05Chicago95th Red Line Station11:35San DiegoOld Town Transit Center0EconomyA Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 19/10/2026 11:05:00 to Old Town Transit Center, San Diego (USA) arriving at 21/10/2026 11:35:00. 50 Economy ticket for £114 per person are available. Travel duration is 50h 30m
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FlixBus61h 5m000:40Chicago95th Red Line Station11:45San DiegoOld Town Transit Center0EconomyA Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 19/10/2026 00:40:00 to Old Town Transit Center, San Diego (USA) arriving at 21/10/2026 11:45:00. 50 Economy ticket for £114 per person are available. Travel duration is 61h 5m
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FlixBus69h 10m023:55Chicago95th Red Line Station19:05San DiegoOld Town Transit Center0EconomyA Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 19/10/2026 23:55:00 to Old Town Transit Center, San Diego (USA) arriving at 22/10/2026 19:05:00. 50 Economy ticket for £114 per person are available. Travel duration is 69h 10m
Fastest Buses Monday
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United Airlines4h 27m007:05Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center09:32San Diego AirportSan Diego Airport0EconomyA Flight from United Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 20/10/2026 07:05:00 to San Diego Airport, San Diego Airport (USA) arriving at 20/10/2026 09:32:00. 50 Economy ticket for £96 per person are available. Travel duration is 4h 27m
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Alaska Airlines4h 36m007:20Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center09:56San Diego AirportSan Diego Airport0EconomyA Flight from Alaska Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 20/10/2026 07:20:00 to San Diego Airport, San Diego Airport (USA) arriving at 20/10/2026 09:56:00. 50 Economy ticket for £96 per person are available. Travel duration is 4h 36m
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United Airlines6h 15m008:40Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center12:55McClellan-Palomar AirportMcClellan-Palomar Airport0EconomyA Flight from United Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 20/10/2026 08:40:00 to McClellan-Palomar Airport, McClellan-Palomar Airport (USA) arriving at 20/10/2026 12:55:00. 50 Economy ticket for £333 per person are available. Travel duration is 6h 15m
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United Airlines7h 35m012:40Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center18:15McClellan-Palomar AirportMcClellan-Palomar Airport0EconomyA Flight from United Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 20/10/2026 12:40:00 to McClellan-Palomar Airport, McClellan-Palomar Airport (USA) arriving at 20/10/2026 18:15:00. 50 Economy ticket for £287 per person are available. Travel duration is 7h 35m
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United Airlines7h 55m007:00Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center12:55McClellan-Palomar AirportMcClellan-Palomar Airport0EconomyA Flight from United Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 20/10/2026 07:00:00 to McClellan-Palomar Airport, McClellan-Palomar Airport (USA) arriving at 20/10/2026 12:55:00. 50 Economy ticket for £286 per person are available. Travel duration is 7h 55m
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United Airlines8h 0m006:07Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center12:07McClellan-Palomar AirportMcClellan-Palomar Airport0EconomyA Flight from United Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 20/10/2026 06:07:00 to McClellan-Palomar Airport, McClellan-Palomar Airport (USA) arriving at 20/10/2026 12:07:00. 50 Economy ticket for £285 per person are available. Travel duration is 8h 0m
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Greyhound US48h 50m012:25ChicagoDowntown Coach Station11:15San DiegoLa Jolla Village0EconomyA Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 20/10/2026 12:25:00 to La Jolla Village, San Diego (USA) arriving at 22/10/2026 11:15:00. 50 Economy ticket for £117 per person are available. Travel duration is 48h 50m
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Greyhound US49h 10m012:25ChicagoDowntown Coach Station11:35San DiegoOld Town Transit Center0EconomyA Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 20/10/2026 12:25:00 to Old Town Transit Center, San Diego (USA) arriving at 22/10/2026 11:35:00. 50 Economy ticket for £117 per person are available. Travel duration is 49h 10m
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Greyhound US49h 30m012:25ChicagoDowntown Coach Station11:55San DiegoSeaport Village0EconomyA Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 20/10/2026 12:25:00 to Seaport Village, San Diego (USA) arriving at 22/10/2026 11:55:00. 50 Economy ticket for £118 per person are available. Travel duration is 49h 30m
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FlixBus57h 15m011:05Chicago95th Red Line Station18:20San DiegoSan Ysidro Transit Center0EconomyA Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 20/10/2026 11:05:00 to San Ysidro Transit Center, San Diego (USA) arriving at 22/10/2026 18:20:00. 50 Economy ticket for £162 per person are available. Travel duration is 57h 15m
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FlixBus74h 35m016:35Chicago95th Red Line Station17:10San DiegoSan Ysidro Transit Center0EconomyA Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 20/10/2026 16:35:00 to San Ysidro Transit Center, San Diego (USA) arriving at 23/10/2026 17:10:00. 50 Economy ticket for £179 per person are available. Travel duration is 74h 35m
Fastest Flights Tuesday
Fastest Buses Tuesday
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United Airlines6h 15m008:40Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center12:55McClellan-Palomar AirportMcClellan-Palomar Airport0EconomyA Flight from United Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 21/10/2026 08:40:00 to McClellan-Palomar Airport, McClellan-Palomar Airport (USA) arriving at 21/10/2026 12:55:00. 50 Economy ticket for £285 per person are available. Travel duration is 6h 15m
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United Airlines6h 18m016:20Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center20:38McClellan-Palomar AirportMcClellan-Palomar Airport0EconomyA Flight from United Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 21/10/2026 16:20:00 to McClellan-Palomar Airport, McClellan-Palomar Airport (USA) arriving at 21/10/2026 20:38:00. 50 Economy ticket for £285 per person are available. Travel duration is 6h 18m
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United Airlines7h 35m012:40Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center18:15McClellan-Palomar AirportMcClellan-Palomar Airport0EconomyA Flight from United Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 21/10/2026 12:40:00 to McClellan-Palomar Airport, McClellan-Palomar Airport (USA) arriving at 21/10/2026 18:15:00. 50 Economy ticket for £285 per person are available. Travel duration is 7h 35m
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United Airlines8h 0m006:07Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center12:07McClellan-Palomar AirportMcClellan-Palomar Airport0EconomyA Flight from United Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 21/10/2026 06:07:00 to McClellan-Palomar Airport, McClellan-Palomar Airport (USA) arriving at 21/10/2026 12:07:00. 50 Economy ticket for £285 per person are available. Travel duration is 8h 0m
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United Airlines8h 55m006:00Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center12:55McClellan-Palomar AirportMcClellan-Palomar Airport0EconomyA Flight from United Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 21/10/2026 06:00:00 to McClellan-Palomar Airport, McClellan-Palomar Airport (USA) arriving at 21/10/2026 12:55:00. 50 Economy ticket for £286 per person are available. Travel duration is 8h 55m
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FlixBus55h 20m011:05Chicago95th Red Line Station16:25San DiegoOld Town Transit Center0EconomyA Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 21/10/2026 11:05:00 to Old Town Transit Center, San Diego (USA) arriving at 23/10/2026 16:25:00. 50 Economy ticket for £101 per person are available. Travel duration is 55h 20m
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Greyhound US60h 20m023:45Chicago95th Red Line Station10:05San DiegoSeaport Village0EconomyA Bus from Greyhound US goes from 95th Red Line Station, Chicago (USA) at 21/10/2026 23:45:00 to Seaport Village, San Diego (USA) arriving at 24/10/2026 10:05:00. 50 Economy ticket for £105 per person are available. Travel duration is 60h 20m
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Greyhound US62h 0m023:45Chicago95th Red Line Station11:45San DiegoOld Town Transit Center0EconomyA Bus from Greyhound US goes from 95th Red Line Station, Chicago (USA) at 21/10/2026 23:45:00 to Old Town Transit Center, San Diego (USA) arriving at 24/10/2026 11:45:00. 50 Economy ticket for £105 per person are available. Travel duration is 62h 0m
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Greyhound US66h 40m023:45Chicago95th Red Line Station16:25San DiegoOld Town Transit Center0EconomyA Bus from Greyhound US goes from 95th Red Line Station, Chicago (USA) at 21/10/2026 23:45:00 to Old Town Transit Center, San Diego (USA) arriving at 24/10/2026 16:25:00. 50 Economy ticket for £101 per person are available. Travel duration is 66h 40m
Fastest Flights Wednesday
Fastest Buses Wednesday
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Aeroméxico11h 45m001:54Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center11:39Tijuana AirportTijuana Airport0EconomyA Flight from Aeroméxico goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 22/10/2026 01:54:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 22/10/2026 11:39:00. 50 Economy ticket for £267 per person are available. Travel duration is 11h 45m
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Volaris13h 2m005:55Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center16:57Tijuana AirportTijuana Airport0EconomyA Flight from Volaris goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 22/10/2026 05:55:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 22/10/2026 16:57:00. 50 Economy ticket for £117 per person are available. Travel duration is 13h 2m
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Alaska Airlines20h 58m017:46Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center12:44Tijuana AirportTijuana Airport0EconomyA Flight from Alaska Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 22/10/2026 17:46:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 23/10/2026 12:44:00. 50 Economy ticket for £497 per person are available. Travel duration is 20h 58m
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Viva Aerobus24h 26m001:30Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center23:56Tijuana AirportTijuana Airport0EconomyA Flight from Viva Aerobus goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 22/10/2026 01:30:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 22/10/2026 23:56:00. 50 Economy ticket for £248 per person are available. Travel duration is 24h 26m
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Frontier Airlines30h 30m019:44Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center00:14Tijuana AirportTijuana Airport0EconomyA Flight from Frontier Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 22/10/2026 19:44:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 24/10/2026 00:14:00. 50 Economy ticket for £281 per person are available. Travel duration is 30h 30m
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Greyhound US49h 35m012:25ChicagoDowntown Coach Station12:00San DiegoSan Ysidro Transit Center0EconomyA Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 22/10/2026 12:25:00 to San Ysidro Transit Center, San Diego (USA) arriving at 24/10/2026 12:00:00. 50 Economy ticket for £144 per person are available. Travel duration is 49h 35m
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FlixBus51h 15m017:05ChicagoDowntown Coach Station18:20San DiegoSan Ysidro Transit Center0EconomyA Bus from FlixBus goes from Downtown Coach Station, Chicago (USA) at 22/10/2026 17:05:00 to San Ysidro Transit Center, San Diego (USA) arriving at 24/10/2026 18:20:00. 50 Economy ticket for £136 per person are available. Travel duration is 51h 15m
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Greyhound US55h 55m012:25ChicagoDowntown Coach Station18:20San DiegoSan Ysidro Transit Center0EconomyA Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 22/10/2026 12:25:00 to San Ysidro Transit Center, San Diego (USA) arriving at 24/10/2026 18:20:00. 50 Economy ticket for £135 per person are available. Travel duration is 55h 55m
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FlixBus57h 15m011:05Chicago95th Red Line Station18:20San DiegoSan Ysidro Transit Center0EconomyA Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 22/10/2026 11:05:00 to San Ysidro Transit Center, San Diego (USA) arriving at 24/10/2026 18:20:00. 50 Economy ticket for £165 per person are available. Travel duration is 57h 15m
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Greyhound US58h 5m010:15ChicagoUnion Station18:20San DiegoSan Ysidro Transit Center0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 22/10/2026 10:15:00 to San Ysidro Transit Center, San Diego (USA) arriving at 24/10/2026 18:20:00. 50 Economy ticket for £136 per person are available. Travel duration is 58h 5m
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Here you will find all operators and timetables for a
Bus from Chicago to San Diego
What are the most popular stations in Chicago and San Diego?
In Chicago, you will usually depart from Downtown Coach Station, 95th Red Line Station or California & 35th Street Coach Stop, while in San Diego you will be arriving at San Ysidro Transit Center, Old Town Transit Center or Santa Fe Depot, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to San Diego from Chicago? With 12 connections between 2 Flight and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Chicago and San Diego, you can pay as low as £83 with a Flight from Frontier Airlines.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from United Airlines: you will get to San Diego in just 4h 25m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Chicago and San Diego are United Airlines, FlixBus and Greyhound US, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Chicago and San Diego is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Cicero, IL or to San Diego Airport, and look at flights from Chicago Midway Airport, and landing at Tijuana Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Chicago to San Diego?
The most popular companies between Chicago and San Diego, are United Airlines, FlixBus and Greyhound US. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: FlixBus and Greyhound US
Airlines: United Airlines, Frontier Airlines, Volaris and 7 more.
All you need to know when you travel from Chicago to San Diego
Check all information on comfort and services on all modes of transports from Chicago to San Diego. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Chicago to San Diego
How can I reach San Diego from Chicago?
Every day, there are on average 12 connections between Flight and Bus, with which you can get to San Diego from Chicago.
How far is San Diego from Chicago?
The distance between Chicago and San Diego is 2,784.7 km.
What is the most ecofriendly mode of transport between Chicago and San Diego?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 75 kgs of CO2, a train 97 kgs, a car 473 kgs, and a flight 685 kgs.
What is the cheapest mode of transport from Chicago to San Diego?
You can get to San Diego with just £83 by taking a Flight from Frontier Airlines.
What is the fastest way to get from Chicago to San Diego?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to San Diego in just 4h 25m with a Flight from United Airlines.
More routes to Chicago and to San Diego
Looking for more options? Here you can see the most popular routes to Chicago and to San Diego. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Chicago
- Aguascalientes to Chicago
- Atlanta, GA to Chicago
- Cincinnati to Chicago
- Cleveland to Chicago
- Columbus, OH to Chicago
- Dallas to Chicago
- Durango, DG to Chicago
- El Paso, TX to Chicago
- Guadalajara, JC to Chicago
- Houston to Chicago
- Las Vegas to Chicago
- Los Angeles to Chicago
- McAllen, TX to Chicago
- Memphis to Chicago
- Mexico City to Chicago
- Nashville to Chicago
- New York to Chicago
- Phoenix, AZ to Chicago
- Pittsburgh to Chicago
- San Antonio, TX to Chicago
- San Luis Potosí to Chicago
- Toronto, ON to Chicago
- Trips to San Diego
- Bakersfield, CA to San Diego
- Cedar City, UT to San Diego
- Dallas to San Diego
- Denver to San Diego
- El Paso, TX to San Diego
- Las Vegas to San Diego
- Los Angeles to San Diego
- Mexico City to San Diego
- New York to San Diego
- Pasco, WA to San Diego
- Phoenix, AZ to San Diego
- Salt Lake City, UT to San Diego
- San Francisco to San Diego
- Seattle, WA to San Diego
- Tucson, AZ to San Diego
