How to get from Chicago to San Diego

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What is the best way to travel from Chicago to San Diego?

Looking for a trip? Check and compare all the available Buses and Flights to San Diego from Chicago. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 2 available companies to find your perfect trip!
Bus is the cheapest and fastest way on this route
Transport type
Travel time
Cheapest price
Average price
Daily departures
Bus
49h 5m
£82
£144
20

What is the cheapest way to reach San Diego from Chicago?

You can reach San Diego with just £82 by taking a Bus from FlixBus, but there are many more cheap offers: we have selected the best ones for you for the next few days here.

Sunday
from £116
Monday
from £162
Tuesday
Wednesday
from £82
Thursday
from £97
Friday
Saturday
from £230

    Cheapest Buses Sunday

  • FlixBus
    53h 0m
    0
    16:30
    Chicago
    Downtown Coach Station
    21:30
    San Diego
    Seaport Village
    0
    FlixBus
    Economy
    £116
  • FlixBus
    49h 40m
    0
    16:30
    Chicago
    Downtown Coach Station
    18:10
    San Diego
    Old Town Transit Center
    0
    FlixBus
    Economy
    £117
  • FlixBus
    49h 5m
    0
    16:30
    Chicago
    Downtown Coach Station
    17:35
    San Diego
    La Jolla Village
    0
    FlixBus
    Economy
    £117
  • Greyhound US
    59h 30m
    0
    10:00
    Chicago
    Union Station
    21:30
    San Diego
    Seaport Village
    0
    Greyhound US
    Economy
    £130
  • Greyhound US
    56h 10m
    0
    10:00
    Chicago
    Union Station
    18:10
    San Diego
    Old Town Transit Center
    0
    Greyhound US
    Economy
    £130

    Cheapest Buses Monday

  • FlixBus
    49h 40m
    0
    16:30
    Chicago
    Downtown Coach Station
    18:10
    San Diego
    Old Town Transit Center
    0
    FlixBus
    Economy
    £162
  • FlixBus
    49h 5m
    0
    16:30
    Chicago
    Downtown Coach Station
    17:35
    San Diego
    La Jolla Village
    0
    FlixBus
    Economy
    £162
  • FlixBus
    54h 15m
    0
    09:45
    Chicago
    Downtown Coach Station
    16:00
    San Diego
    La Jolla Village
    0
    FlixBus
    Economy
    £165
  • Greyhound US
    59h 30m
    0
    22:00
    Chicago
    Union Station
    09:30
    San Diego
    Old Town Transit Center
    0
    Greyhound US
    Economy
    £182
  • Greyhound US
    71h 30m
    0
    22:00
    Chicago
    Union Station
    21:30
    San Diego
    Seaport Village
    0
    Greyhound US
    Economy
    £183

    Cheapest Buses Wednesday

  • FlixBus
    49h 15m
    0
    16:30
    Chicago
    Downtown Coach Station
    17:45
    San Diego
    Old Town Transit Center
    0
    FlixBus
    Economy
    £82
  • FlixBus
    53h 0m
    0
    16:30
    Chicago
    Downtown Coach Station
    21:30
    San Diego
    Seaport Village
    0
    FlixBus
    Economy
    £82
  • FlixBus
    49h 40m
    0
    16:30
    Chicago
    Downtown Coach Station
    18:10
    San Diego
    Old Town Transit Center
    0
    FlixBus
    Economy
    £86
  • Greyhound US
    59h 30m
    0
    10:00
    Chicago
    Union Station
    21:30
    San Diego
    Seaport Village
    0
    Greyhound US
    Economy
    £92
  • Greyhound US
    56h 10m
    0
    10:00
    Chicago
    Union Station
    18:10
    San Diego
    Old Town Transit Center
    0
    Greyhound US
    Economy
    £96

    Cheapest Buses Thursday

  • FlixBus
    53h 0m
    0
    16:30
    Chicago
    Downtown Coach Station
    21:30
    San Diego
    Seaport Village
    0
    FlixBus
    Economy
    £97
  • FlixBus
    49h 15m
    0
    16:30
    Chicago
    Downtown Coach Station
    17:45
    San Diego
    Old Town Transit Center
    0
    FlixBus
    Economy
    £98
  • FlixBus
    49h 40m
    0
    16:30
    Chicago
    Downtown Coach Station
    18:10
    San Diego
    Old Town Transit Center
    0
    FlixBus
    Economy
    £99
  • Greyhound US
    65h 40m
    0
    22:00
    Chicago
    Union Station
    15:40
    San Diego
    SDSU Transit Center
    0
    Greyhound US
    Economy
    £112
  • Greyhound US
    60h 40m
    0
    22:00
    Chicago
    Union Station
    10:40
    San Diego
    Seaport Village
    0
    Greyhound US
    Economy
    £123

    Cheapest Buses Saturday

  • FlixBus
    58h 25m
    0
    00:15
    Chicago
    Downtown Coach Station
    10:40
    San Diego
    Seaport Village
    0
    FlixBus
    Economy
    £230
  • FlixBus
    49h 15m
    0
    16:30
    Chicago
    Downtown Coach Station
    17:45
    San Diego
    Old Town Transit Center
    0
    FlixBus
    Economy
    £231
  • Greyhound US
    56h 10m
    0
    10:00
    Chicago
    Union Station
    18:10
    San Diego
    Old Town Transit Center
    0
    Greyhound US
    Economy
    £232
  • Greyhound US
    55h 35m
    0
    10:00
    Chicago
    Union Station
    17:35
    San Diego
    La Jolla Village
    0
    Greyhound US
    Economy
    £232
  • Greyhound US
    59h 30m
    0
    10:00
    Chicago
    Union Station
    21:30
    San Diego
    Seaport Village
    0
    Greyhound US
    Economy
    £233

What are the fastest trips from Chicago to San Diego?

You can get to San Diego from Chicago in just 49h 5m with a Bus from FlixBus. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.

Sunday
from 49h 5m
Monday
from 49h 5m
Tuesday
Wednesday
from 49h 15m
Thursday
from 49h 15m
Friday
Saturday
from 49h 15m

    Fastest Buses Sunday

  • FlixBus
    49h 5m
    0
    16:30
    Chicago
    Downtown Coach Station
    17:35
    San Diego
    La Jolla Village
    0
    FlixBus
    Economy
    £117
  • FlixBus
    49h 40m
    0
    16:30
    Chicago
    Downtown Coach Station
    18:10
    San Diego
    Old Town Transit Center
    0
    FlixBus
    Economy
    £117
  • FlixBus
    53h 0m
    0
    16:30
    Chicago
    Downtown Coach Station
    21:30
    San Diego
    Seaport Village
    0
    FlixBus
    Economy
    £116
  • Greyhound US
    56h 10m
    0
    10:00
    Chicago
    Union Station
    18:10
    San Diego
    Old Town Transit Center
    0
    Greyhound US
    Economy
    £130
  • Greyhound US
    59h 30m
    0
    10:00
    Chicago
    Union Station
    21:30
    San Diego
    Seaport Village
    0
    Greyhound US
    Economy
    £130

    Fastest Buses Monday

  • FlixBus
    49h 5m
    0
    16:30
    Chicago
    Downtown Coach Station
    17:35
    San Diego
    La Jolla Village
    0
    FlixBus
    Economy
    £162
  • FlixBus
    49h 40m
    0
    16:30
    Chicago
    Downtown Coach Station
    18:10
    San Diego
    Old Town Transit Center
    0
    FlixBus
    Economy
    £162
  • FlixBus
    54h 15m
    0
    09:45
    Chicago
    Downtown Coach Station
    16:00
    San Diego
    La Jolla Village
    0
    FlixBus
    Economy
    £165
  • Greyhound US
    59h 30m
    0
    22:00
    Chicago
    Union Station
    09:30
    San Diego
    Old Town Transit Center
    0
    Greyhound US
    Economy
    £182
  • Greyhound US
    71h 30m
    0
    22:00
    Chicago
    Union Station
    21:30
    San Diego
    Seaport Village
    0
    Greyhound US
    Economy
    £183

    Fastest Buses Wednesday

  • FlixBus
    49h 15m
    0
    16:30
    Chicago
    Downtown Coach Station
    17:45
    San Diego
    Old Town Transit Center
    0
    FlixBus
    Economy
    £82
  • FlixBus
    49h 40m
    0
    16:30
    Chicago
    Downtown Coach Station
    18:10
    San Diego
    Old Town Transit Center
    0
    FlixBus
    Economy
    £86
  • FlixBus
    53h 0m
    0
    16:30
    Chicago
    Downtown Coach Station
    21:30
    San Diego
    Seaport Village
    0
    FlixBus
    Economy
    £82
  • Greyhound US
    56h 10m
    0
    10:00
    Chicago
    Union Station
    18:10
    San Diego
    Old Town Transit Center
    0
    Greyhound US
    Economy
    £96
  • Greyhound US
    59h 30m
    0
    10:00
    Chicago
    Union Station
    21:30
    San Diego
    Seaport Village
    0
    Greyhound US
    Economy
    £92

    Fastest Buses Thursday

  • FlixBus
    49h 15m
    0
    16:30
    Chicago
    Downtown Coach Station
    17:45
    San Diego
    Old Town Transit Center
    0
    FlixBus
    Economy
    £98
  • FlixBus
    49h 40m
    0
    16:30
    Chicago
    Downtown Coach Station
    18:10
    San Diego
    Old Town Transit Center
    0
    FlixBus
    Economy
    £99
  • FlixBus
    53h 0m
    0
    16:30
    Chicago
    Downtown Coach Station
    21:30
    San Diego
    Seaport Village
    0
    FlixBus
    Economy
    £97
  • Greyhound US
    60h 40m
    0
    22:00
    Chicago
    Union Station
    10:40
    San Diego
    Seaport Village
    0
    Greyhound US
    Economy
    £123
  • Greyhound US
    65h 40m
    0
    22:00
    Chicago
    Union Station
    15:40
    San Diego
    SDSU Transit Center
    0
    Greyhound US
    Economy
    £112

    Fastest Buses Saturday

  • FlixBus
    49h 15m
    0
    16:30
    Chicago
    Downtown Coach Station
    17:45
    San Diego
    Old Town Transit Center
    0
    FlixBus
    Economy
    £231
  • Greyhound US
    55h 35m
    0
    10:00
    Chicago
    Union Station
    17:35
    San Diego
    La Jolla Village
    0
    Greyhound US
    Economy
    £232
  • Greyhound US
    56h 10m
    0
    10:00
    Chicago
    Union Station
    18:10
    San Diego
    Old Town Transit Center
    0
    Greyhound US
    Economy
    £232
  • FlixBus
    58h 25m
    0
    00:15
    Chicago
    Downtown Coach Station
    10:40
    San Diego
    Seaport Village
    0
    FlixBus
    Economy
    £230
  • Greyhound US
    59h 30m
    0
    10:00
    Chicago
    Union Station
    21:30
    San Diego
    Seaport Village
    0
    Greyhound US
    Economy
    £233
Here you will find all operators and timetables for a Bus from Chicago to San Diego

What are the most popular stations in Chicago and San Diego?

In Chicago, you will usually depart from Union Station, 95th Red Line Station or California & 35th Street Coach Stop, while in San Diego you will be arriving at Santa Fe Depot, San Ysidro Transit Center or Old Town Transit Center, but there are many more stops to explore in both locations.

How do I decide? Some tips and tricks from our experience

Are you having trouble deciding on how to get to San Diego from Chicago? With 5 connections between 2 Bus and Flight operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.

Look for the lowest price

Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Chicago and San Diego, you can pay as low as £82 with a Bus from FlixBus.

Travel duration

Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Bus from FlixBus: you will get to San Diego in just 49h 5m.

Comfort makes all the difference

You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Chicago and San Diego are FlixBus and Greyhound US, but be sure to check what they have to offer!

Save money with deals, and always compare

One last tip? Even if you live in Chicago and San Diego is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Cicero, IL or to San Diego Airport, and look at flights from Chicago Midway Airport, and landing at Tijuana Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!

Which companies offer a trip from Chicago to San Diego?

The most popular companies between Chicago and San Diego, are FlixBus and Greyhound US. Be sure to check their seat class offers and the amenities that they provide.

Bus companies: FlixBus and Greyhound US

All you need to know when you travel from Chicago to San Diego

Check all information on comfort and services on all modes of transports from Chicago to San Diego. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.

FAQs about the trip from Chicago to San Diego

How can I reach San Diego from Chicago?

Every day, there are on average 5 connections between Bus and Flight, with which you can get to San Diego from Chicago.

How far is San Diego from Chicago?

The distance between Chicago and San Diego is 2,784.7 km.

What is the most ecofriendly mode of transport between Chicago and San Diego?

Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance. On this particular route, a bus will emit, per person, a total of 75 kgs of CO2, a train 97 kgs, a car 473 kgs, and a flight 685 kgs.

What is the cheapest mode of transport from Chicago to San Diego?

You can get to San Diego with just £82 by taking a Bus from FlixBus.

What is the fastest way to get from Chicago to San Diego?

While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to San Diego in just 49h 5m with a Bus from FlixBus.

More routes to Chicago and to San Diego

Looking for more options? Here you can see the most popular routes to Chicago and to San Diego. Simply click on a connection, and you’ll find all the details about the route!

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