Bus and Coach from São Paulo to Santa Cruz de la Sierra: Compare all prices

Compare all timetables for the bus from São Paulo to Santa Cruz de la Sierra

Here is a selection of the cheapest bus trips from the schedule from São Paulo to Santa Cruz de la Sierra from various bus operators like La Preferida Bus for the next days.

today

£207

tomorrow

£207

Monday

£207

Tuesday

£207

Wednesday

Thursday

£207

Friday

Cheapest bus trips today
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	La Preferida Bus	38h 30m	13:00	São Paulo	Barra Funda Bus Station	03:30	Santa Cruz de la Sierra	Terminal Bimodal		First Class	£207	A Bus from La Preferida Bus goes from Barra Funda Bus Station, São Paulo (Brazil) at 13/12/2025 13:00:00 to Terminal Bimodal, Santa Cruz de la Sierra (Bolivia) arriving at 15/12/2025 03:30:00. 50 First Class ticket for £207 per person are available. Travel duration is 38h 30m

Cheapest bus trips tomorrow
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	La Preferida Bus	38h 30m	13:00	São Paulo	Barra Funda Bus Station	03:30	Santa Cruz de la Sierra	Terminal Bimodal		First Class	£207	A Bus from La Preferida Bus goes from Barra Funda Bus Station, São Paulo (Brazil) at 14/12/2025 13:00:00 to Terminal Bimodal, Santa Cruz de la Sierra (Bolivia) arriving at 16/12/2025 03:30:00. 50 First Class ticket for £207 per person are available. Travel duration is 38h 30m

Cheapest bus trips Monday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	La Preferida Bus	38h 30m	13:00	São Paulo	Barra Funda Bus Station	03:30	Santa Cruz de la Sierra	Terminal Bimodal		First Class	£207	A Bus from La Preferida Bus goes from Barra Funda Bus Station, São Paulo (Brazil) at 15/12/2025 13:00:00 to Terminal Bimodal, Santa Cruz de la Sierra (Bolivia) arriving at 17/12/2025 03:30:00. 50 First Class ticket for £207 per person are available. Travel duration is 38h 30m

Did you know that if you travel from São Paulo to Santa Cruz de la Sierra via Asunción, PY, you can save more than £70? You can find the corresponding connections below.
- DeÔnibus
  
  50h 0m
  
  0
  
  15:00
  
  São Paulo
  Tietê Bus Station
  
  12:26
  
  Asunción, PY
  Coach Station
  
  0
  
  First Class
  
  £81
  
  A Bus from DeÔnibus goes from Tietê Bus Station, São Paulo (Brazil) at 16/12/2025 15:00:00 to Coach Station, Asunción, PY (Paraguay) arriving at 17/12/2025 12:26:00. 50 First Class ticket for £81 per person are available. Travel duration is 21h 26m
- Plataforma 10
  
  21h 0m
  
  0
  
  20:00
  
  Asunción, PY
  Coach Station
  
  16:00
  
  Santa Cruz de la Sierra
  Terminal Bimodal
  
  0
  
  Premium Economy
  
  £56
  
  A Bus from Plataforma 10 goes from Coach Station, Asunción, PY (Paraguay) at 17/12/2025 20:00:00 to Terminal Bimodal, Santa Cruz de la Sierra (Bolivia) arriving at 18/12/2025 16:00:00. 50 Premium Economy ticket for £56 per person are available. Travel duration is 21h 0m
Travel time is 11h 30m longer, but you will save £70

Cheapest bus trips Tuesday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	La Preferida Bus	38h 30m	13:00	São Paulo	Barra Funda Bus Station	03:30	Santa Cruz de la Sierra	Terminal Bimodal		First Class	£207	A Bus from La Preferida Bus goes from Barra Funda Bus Station, São Paulo (Brazil) at 16/12/2025 13:00:00 to Terminal Bimodal, Santa Cruz de la Sierra (Bolivia) arriving at 18/12/2025 03:30:00. 50 First Class ticket for £207 per person are available. Travel duration is 38h 30m

Did you know that if you travel from São Paulo to Santa Cruz de la Sierra via Asunción, PY, you can save more than £70? You can find the corresponding connections below.
- DeÔnibus
  
  50h 0m
  
  0
  
  15:00
  
  São Paulo
  Tietê Bus Station
  
  12:26
  
  Asunción, PY
  Coach Station
  
  0
  
  First Class
  
  £81
  
  A Bus from DeÔnibus goes from Tietê Bus Station, São Paulo (Brazil) at 16/12/2025 15:00:00 to Coach Station, Asunción, PY (Paraguay) arriving at 17/12/2025 12:26:00. 50 First Class ticket for £81 per person are available. Travel duration is 21h 26m
- Plataforma 10
  
  21h 0m
  
  0
  
  20:00
  
  Asunción, PY
  Coach Station
  
  16:00
  
  Santa Cruz de la Sierra
  Terminal Bimodal
  
  0
  
  Premium Economy
  
  £56
  
  A Bus from Plataforma 10 goes from Coach Station, Asunción, PY (Paraguay) at 17/12/2025 20:00:00 to Terminal Bimodal, Santa Cruz de la Sierra (Bolivia) arriving at 18/12/2025 16:00:00. 50 Premium Economy ticket for £56 per person are available. Travel duration is 21h 0m
Travel time is 11h 30m longer, but you will save £70

Cheapest bus trips Thursday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	La Preferida Bus	38h 30m	13:00	São Paulo	Barra Funda Bus Station	03:30	Santa Cruz de la Sierra	Terminal Bimodal		First Class	£207	A Bus from La Preferida Bus goes from Barra Funda Bus Station, São Paulo (Brazil) at 18/12/2025 13:00:00 to Terminal Bimodal, Santa Cruz de la Sierra (Bolivia) arriving at 20/12/2025 03:30:00. 50 First Class ticket for £207 per person are available. Travel duration is 38h 30m

Did you know that if you travel from São Paulo to Santa Cruz de la Sierra via Asunción, PY, you can save more than £70? You can find the corresponding connections below.
- DeÔnibus
  
  50h 0m
  
  0
  
  15:00
  
  São Paulo
  Tietê Bus Station
  
  12:26
  
  Asunción, PY
  Coach Station
  
  0
  
  First Class
  
  £81
  
  A Bus from DeÔnibus goes from Tietê Bus Station, São Paulo (Brazil) at 16/12/2025 15:00:00 to Coach Station, Asunción, PY (Paraguay) arriving at 17/12/2025 12:26:00. 50 First Class ticket for £81 per person are available. Travel duration is 21h 26m
- Plataforma 10
  
  21h 0m
  
  0
  
  20:00
  
  Asunción, PY
  Coach Station
  
  16:00
  
  Santa Cruz de la Sierra
  Terminal Bimodal
  
  0
  
  Premium Economy
  
  £56
  
  A Bus from Plataforma 10 goes from Coach Station, Asunción, PY (Paraguay) at 17/12/2025 20:00:00 to Terminal Bimodal, Santa Cruz de la Sierra (Bolivia) arriving at 18/12/2025 16:00:00. 50 Premium Economy ticket for £56 per person are available. Travel duration is 21h 0m
Travel time is 11h 30m longer, but you will save £70

Best Price Offer: The price for the cheapest coach from São Paulo to Santa Cruz de la Sierra is £186 on 01/01/2026. Flexible travellers save on ticket prices.

Facts about coaches from São Paulo to Santa Cruz de la Sierra

Compare all providers like La Preferida Bus that travel 1 times every day by bus from São Paulo to Santa Cruz de la Sierra in one click! Book your bus ticket from São Paulo to Santa Cruz de la Sierra starting from £186!

Cheapest Bus	£186
Fastest Bus	38h 30m
Earliest Coach	13:00
Latest Coach	13:00
Daily Bus Connections	1 Ø
Distance	1,835.4 km
Coach Companies	La Preferida Bus

Cheapest coach connections from São Paulo to Santa Cruz de la Sierra

Every day, 1 buses from 1 coach companies leave São Paulo for Santa Cruz de la Sierra: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 13/12/2025 and for the following days.

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday

Monday 08/12

Tuesday 09/12

Wednesday 10/12

Thursday 11/12

Friday 12/12

Saturday 13/12

£207

Sunday 14/12

£207

Monday 15/12

£207

Tuesday 16/12

£207

Wednesday 17/12

Thursday 18/12

£207

Friday 19/12

Saturday 20/12

£207

Sunday 21/12

£207

Monday 22/12

£207

Tuesday 23/12

Wednesday 24/12

£207

Thursday 25/12

Friday 26/12

Saturday 27/12

Sunday 28/12

Monday 29/12

£207

Tuesday 30/12

£207

Wednesday 31/12

Thursday 01/01

£186

Friday 02/01

Saturday 03/01

£186

Sunday 04/01

How to save money travelling from São Paulo to Santa Cruz de la Sierra

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from São Paulo to Santa Cruz de la Sierra in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from São Paulo to Santa Cruz de la Sierra, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from São Paulo to Santa Cruz de la Sierra are also emptier.

All bus stations and stops in São Paulo and Santa Cruz de la Sierra

The map below shows you where to find all the bus stations in São Paulo and Santa Cruz de la Sierra.

Tietê Bus Station

Vila Guilherme

Barra Funda Bus Station

Rua Aloysio Biondi, s/n Barra Funda

Sala VIP Bella Vita

Av. Ordem e Progresso 95

Jabaquara Coach Station

Avenida Engenheiro Armando de Arruda Pereira 2022

Shopping Feira da Madrugada Coach Stop

Rua São Caetano 812

Terminal Bimodal

Av Intermodal

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from São Paulo to Santa Cruz de la Sierra? Compare all modes of transports from São Paulo to Santa Cruz de la Sierra.

Service and Comfort on the bus from São Paulo to Santa Cruz de la Sierra

Want to know which seat classes are available on the coaches from São Paulo to Santa Cruz de la Sierra? Or which bus companies serve the route São Paulo to Santa Cruz de la Sierra? Below you will find answers to your questions.

FAQs about the São Paulo to Santa Cruz de la Sierra bus

How much does a São Paulo - Santa Cruz de la Sierra coach trip cost?

This depends on, among other things, the day and travel time. The cheapest ticket for the São Paulo - Santa Cruz de la Sierra bus trip is available from £186 and takes 38h 30m. Compare offers and save money!

How much could I save by comparing buses from São Paulo to Santa Cruz de la Sierra?

The connection São Paulo to Santa Cruz de la Sierra is offered by 1 companies with ticket prices ranging from £186 to £207. Therefore, we suggest booking your ticket as soon as possible to ensure you will get the cheapest ticket price.

How many connections are available for the São Paulo - Santa Cruz de la Sierra route on average every day?

Each day, the bus route from São Paulo to Santa Cruz de la Sierra is offered by roughly 1 busses. By using our search, you can compare bus schedules and find your ideal trip.

How long does a bus to Santa Cruz de la Sierra from São Paulo take?

The quickest coach from São Paulo to Santa Cruz de la Sierra is provided by La Preferida Bus and takes 38h 30m. Coach tickets for this connection cost £207. However, keep in mind that the connection can take longer due to traffic.

What time is the first bus from São Paulo to Santa Cruz de la Sierra?

The earliest bus to Santa Cruz de la Sierra departs from São Paulo at 13:00. In this context, information about departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

What time is the last coach from São Paulo to Santa Cruz de la Sierra?

The latest bus to Santa Cruz de la Sierra departs from São Paulo at 13:00. Please note that departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

Which bus companies serve the São Paulo - Santa Cruz de la Sierra route?

Passengers looking to travel from São Paulo to Santa Cruz de la Sierra can travel with La Preferida Bus. Compare all available bus tickets with our search to book the trip that works best for you.

Is there a direct bus between São Paulo and Santa Cruz de la Sierra?

You can check all the direct connections between São Paulo and Santa Cruz de la Sierra by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: La Preferida Bus.

What can I take with me on the bus to Santa Cruz de la Sierra from São Paulo?

Depending on which provider you travel with, what you are allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the bus for the São Paulo Santa Cruz de la Sierra bus route free of charge. Simply use our search to find a coach that is best suited to your needs for your planned travel date.

What equipment is available for the São Paulo Santa Cruz de la Sierra bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make travelling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from São Paulo to Santa Cruz de la Sierra on your planned travel date.

Available seat classes which are offered on the bus route São Paulo to Santa Cruz de la Sierra

First Class

Best of the best: you will find the most comfortable accommodation to work or relax during your travel.

More bus routes to São Paulo and to Santa Cruz de la Sierra

Here’s an overview of the most popular bus routes to São Paulo and to Santa Cruz de la Sierra. Simply click on the connection of your choice, and you will find all the details about your bus route!