Bus and Coach from Santiago Tuxtla to Mexico City: Compare all prices

Compare all timetables for the bus from Santiago Tuxtla to Mexico City

Here is a selection of the cheapest bus trips from the schedule from Santiago Tuxtla to Mexico City from various bus operators like ADO for the next days.

today

£52

tomorrow

Sunday

£52

Monday

Tuesday

Wednesday

£52

Thursday

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
ADO	8h 55m	21:20	Santiago Tuxtla	Central Bus Station	06:15	Mexico City	Terminal de Autobuses de Oriente (TAPO)	Economy	£52	A Bus from ADO goes from Central Bus Station, Santiago Tuxtla (Mexico) at 19/12/2025 21:20:00 to Terminal de Autobuses de Oriente (TAPO), Mexico City (Mexico) arriving at 20/12/2025 06:15:00. 50 Economy ticket for £52 per person are available. Travel duration is 8h 55m
ADO	8h 55m	22:05	Santiago Tuxtla	Central Bus Station	07:00	Mexico City	Terminal de Autobuses de Oriente (TAPO)	Economy	£52	A Bus from ADO goes from Central Bus Station, Santiago Tuxtla (Mexico) at 19/12/2025 22:05:00 to Terminal de Autobuses de Oriente (TAPO), Mexico City (Mexico) arriving at 20/12/2025 07:00:00. 50 Economy ticket for £52 per person are available. Travel duration is 8h 55m
ADO	9h 15m	22:20	Santiago Tuxtla	Central Bus Station	07:35	Mexico City	Terminal de Autobuses de Oriente (TAPO)	Economy	£52	A Bus from ADO goes from Central Bus Station, Santiago Tuxtla (Mexico) at 19/12/2025 22:20:00 to Terminal de Autobuses de Oriente (TAPO), Mexico City (Mexico) arriving at 20/12/2025 07:35:00. 50 Economy ticket for £52 per person are available. Travel duration is 9h 15m
ADO	10h 0m	22:20	Santiago Tuxtla	Central Bus Station	08:20	Mexico City	Norte Bus Station	Economy	£52	A Bus from ADO goes from Central Bus Station, Santiago Tuxtla (Mexico) at 19/12/2025 22:20:00 to Norte Bus Station, Mexico City (Mexico) arriving at 20/12/2025 08:20:00. 50 Economy ticket for £52 per person are available. Travel duration is 10h 0m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
ADO	9h 5m	21:20	Santiago Tuxtla	Central Bus Station	06:25	Mexico City	Terminal de Autobuses de Oriente (TAPO)	Economy	£52	A Bus from ADO goes from Central Bus Station, Santiago Tuxtla (Mexico) at 21/12/2025 21:20:00 to Terminal de Autobuses de Oriente (TAPO), Mexico City (Mexico) arriving at 22/12/2025 06:25:00. 50 Economy ticket for £52 per person are available. Travel duration is 9h 5m
ADO	9h 5m	22:05	Santiago Tuxtla	Central Bus Station	07:10	Mexico City	Terminal de Autobuses de Oriente (TAPO)	Economy	£52	A Bus from ADO goes from Central Bus Station, Santiago Tuxtla (Mexico) at 21/12/2025 22:05:00 to Terminal de Autobuses de Oriente (TAPO), Mexico City (Mexico) arriving at 22/12/2025 07:10:00. 50 Economy ticket for £52 per person are available. Travel duration is 9h 5m
ADO	9h 15m	22:20	Santiago Tuxtla	Central Bus Station	07:35	Mexico City	Terminal de Autobuses de Oriente (TAPO)	Economy	£52	A Bus from ADO goes from Central Bus Station, Santiago Tuxtla (Mexico) at 21/12/2025 22:20:00 to Terminal de Autobuses de Oriente (TAPO), Mexico City (Mexico) arriving at 22/12/2025 07:35:00. 50 Economy ticket for £52 per person are available. Travel duration is 9h 15m
ADO	9h 5m	23:40	Santiago Tuxtla	Central Bus Station	08:45	Mexico City	Terminal de Autobuses de Oriente (TAPO)	Economy	£52	A Bus from ADO goes from Central Bus Station, Santiago Tuxtla (Mexico) at 21/12/2025 23:40:00 to Terminal de Autobuses de Oriente (TAPO), Mexico City (Mexico) arriving at 22/12/2025 08:45:00. 50 Economy ticket for £52 per person are available. Travel duration is 9h 5m
ADO	10h 0m	22:20	Santiago Tuxtla	Central Bus Station	08:20	Mexico City	Norte Bus Station	Economy	£52	A Bus from ADO goes from Central Bus Station, Santiago Tuxtla (Mexico) at 21/12/2025 22:20:00 to Norte Bus Station, Mexico City (Mexico) arriving at 22/12/2025 08:20:00. 50 Economy ticket for £52 per person are available. Travel duration is 10h 0m

Did you know that if you travel from Santiago Tuxtla to Mexico City via Puebla City, PL, you can save more than £13? You can find the corresponding connections below.
- ClickBus MX
  
  10h 5m
  
  0
  
  11:55
  
  Santiago Tuxtla
  Central Bus Station
  
  18:10
  
  Puebla City, PL
  Central Bus Station (CAPU)
  
  0
  
  Economy
  
  £32
  
  A Bus from ClickBus MX goes from Central Bus Station, Santiago Tuxtla (Mexico) at 23/12/2025 11:55:00 to Central Bus Station (CAPU), Puebla City, PL (Mexico) arriving at 23/12/2025 18:10:00. 50 Economy ticket for £32 per person are available. Travel duration is 6h 15m
- Busbud
  
  2h 0m
  
  0
  
  20:00
  
  Puebla City, PL
  Central Bus Station (CAPU)
  
  22:00
  
  Mexico City
  Calz. Ignacio Zaragoza
  
  0
  
  Economy
  
  £8
  
  A Bus from Busbud goes from Central Bus Station (CAPU), Puebla City, PL (Mexico) at 23/12/2025 20:00:00 to Calz. Ignacio Zaragoza, Mexico City (Mexico) arriving at 23/12/2025 22:00:00. 50 Economy ticket for £8 per person are available. Travel duration is 2h 0m
Travel time is 1h 0m longer, but you will save £13

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
ADO	8h 55m	21:20	Santiago Tuxtla	Central Bus Station	06:15	Mexico City	Terminal de Autobuses de Oriente (TAPO)	Economy	£52	A Bus from ADO goes from Central Bus Station, Santiago Tuxtla (Mexico) at 24/12/2025 21:20:00 to Terminal de Autobuses de Oriente (TAPO), Mexico City (Mexico) arriving at 25/12/2025 06:15:00. 50 Economy ticket for £52 per person are available. Travel duration is 8h 55m
ADO	8h 55m	22:05	Santiago Tuxtla	Central Bus Station	07:00	Mexico City	Terminal de Autobuses de Oriente (TAPO)	Economy	£52	A Bus from ADO goes from Central Bus Station, Santiago Tuxtla (Mexico) at 24/12/2025 22:05:00 to Terminal de Autobuses de Oriente (TAPO), Mexico City (Mexico) arriving at 25/12/2025 07:00:00. 50 Economy ticket for £52 per person are available. Travel duration is 8h 55m
ADO	9h 15m	22:20	Santiago Tuxtla	Central Bus Station	07:35	Mexico City	Terminal de Autobuses de Oriente (TAPO)	Economy	£52	A Bus from ADO goes from Central Bus Station, Santiago Tuxtla (Mexico) at 24/12/2025 22:20:00 to Terminal de Autobuses de Oriente (TAPO), Mexico City (Mexico) arriving at 25/12/2025 07:35:00. 50 Economy ticket for £52 per person are available. Travel duration is 9h 15m
ADO	10h 0m	22:20	Santiago Tuxtla	Central Bus Station	08:20	Mexico City	Norte Bus Station	Economy	£52	A Bus from ADO goes from Central Bus Station, Santiago Tuxtla (Mexico) at 24/12/2025 22:20:00 to Norte Bus Station, Mexico City (Mexico) arriving at 25/12/2025 08:20:00. 50 Economy ticket for £52 per person are available. Travel duration is 10h 0m

Did you know that if you travel from Santiago Tuxtla to Mexico City via Veracruz, you can save more than £14? You can find the corresponding connections below.
- ClickBus MX
  
  12h 20m
  
  0
  
  14:10
  
  Santiago Tuxtla
  Central Bus Station
  
  17:05
  
  Veracruz
  Central bus station
  
  0
  
  Economy
  
  £14
  
  A Bus from ClickBus MX goes from Central Bus Station, Santiago Tuxtla (Mexico) at 26/12/2025 14:10:00 to Central bus station, Veracruz (Mexico) arriving at 26/12/2025 17:05:00. 50 Economy ticket for £14 per person are available. Travel duration is 2h 55m
- ClickBus MX
  
  6h 30m
  
  0
  
  20:00
  
  Veracruz
  Bus Stop
  
  02:30
  
  Mexico City
  Norte Bus Station
  
  0
  
  Economy
  
  £24
  
  A Bus from ClickBus MX goes from Bus Stop, Veracruz (Mexico) at 26/12/2025 20:00:00 to Norte Bus Station, Mexico City (Mexico) arriving at 27/12/2025 02:30:00. 50 Economy ticket for £24 per person are available. Travel duration is 6h 30m
Travel time is 3h 25m longer, but you will save £14

Best Price Offer: The price for the cheapest coach from Santiago Tuxtla to Mexico City is £49 on 15/12/2025. Flexible travellers save on ticket prices.

Facts about coaches from Santiago Tuxtla to Mexico City

Compare all providers like ADO that travel 9 times every day by bus from Santiago Tuxtla to Mexico City in one click! Book your bus ticket from Santiago Tuxtla to Mexico City starting from £49!

Cheapest Bus	£49
Fastest Bus	8h 55m
Earliest Coach	21:20
Latest Coach	22:20
Daily Bus Connections	9 Ø
Distance	417.0 km
Coach Companies	ADO

Cheapest coach connections from Santiago Tuxtla to Mexico City

Every day, 9 buses from 1 coach companies leave Santiago Tuxtla for Mexico City: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 19/12/2025 and for the following days.

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday

Monday 15/12

Tuesday 16/12

Wednesday 17/12

Thursday 18/12

Friday 19/12

£52

Saturday 20/12

Sunday 21/12

£52

Monday 22/12

Tuesday 23/12

Wednesday 24/12

£52

Thursday 25/12

Friday 26/12

Saturday 27/12

Sunday 28/12

£52

Monday 29/12

Tuesday 30/12

£50

Wednesday 31/12

Thursday 01/01

Friday 02/01

Saturday 03/01

£52

Sunday 04/01

Monday 05/01

Tuesday 06/01

Wednesday 07/01

Thursday 08/01

Friday 09/01

Saturday 10/01

Sunday 11/01

How to save money travelling from Santiago Tuxtla to Mexico City

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Santiago Tuxtla to Mexico City in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Santiago Tuxtla to Mexico City, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Santiago Tuxtla to Mexico City are also emptier.

All bus stations and stops in Santiago Tuxtla and Mexico City

The map below shows you where to find all the bus stations in Santiago Tuxtla and Mexico City.

Central Bus Station

Morelos 190

Norte Bus Station

Eje Central Lázaro Cárdenas

Terminal de Autobuses de Oriente (TAPO)

Calz. Ignacio Zaragoza 200

Terminal del Sur

Av. Taxqueña 1320

Observatorio Central Coach Station

Av Río de Tacubaya 122 232

Terminal Antas Tla

Emiliano Zapata 97

Service and Comfort on the bus from Santiago Tuxtla to Mexico City

Want to know which seat classes are available on the coaches from Santiago Tuxtla to Mexico City? Or which bus companies serve the route Santiago Tuxtla to Mexico City? Below you will find answers to your questions.

FAQs about the Santiago Tuxtla to Mexico City bus

How much does a Santiago Tuxtla - Mexico City coach trip cost?

This depends on, among other things, the day and travel time. The cheapest ticket for the Santiago Tuxtla - Mexico City bus trip is available from £49 and takes 8h 55m. Compare offers and save money!

How much could I save by comparing buses from Santiago Tuxtla to Mexico City?

The connection Santiago Tuxtla to Mexico City is offered by 1 companies with ticket prices ranging from £49 to £53. Therefore, we suggest booking your ticket as soon as possible to ensure you will get the cheapest ticket price.

How many connections are available for the Santiago Tuxtla - Mexico City route on average every day?

Each day, the bus route from Santiago Tuxtla to Mexico City is offered by roughly 9 busses. By using our search, you can compare bus schedules and find your ideal trip.

How long does a bus to Mexico City from Santiago Tuxtla take?

The quickest coach from Santiago Tuxtla to Mexico City is provided by ADO and takes 8h 55m. Coach tickets for this connection cost £53. However, keep in mind that the connection can take longer due to traffic.

What time is the first bus from Santiago Tuxtla to Mexico City?

The earliest bus to Mexico City departs from Santiago Tuxtla at 21:20. In this context, information about departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

What time is the last coach from Santiago Tuxtla to Mexico City?

The latest bus to Mexico City departs from Santiago Tuxtla at 22:20. Please note that departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

Which bus companies serve the Santiago Tuxtla - Mexico City route?

Passengers looking to travel from Santiago Tuxtla to Mexico City can travel with ADO. Compare all available bus tickets with our search to book the trip that works best for you.

Is there a direct bus between Santiago Tuxtla and Mexico City?

You can check all the direct connections between Santiago Tuxtla and Mexico City by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: ADO.

What can I take with me on the bus to Mexico City from Santiago Tuxtla?

Depending on which provider you travel with, what you are allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the bus for the Santiago Tuxtla Mexico City bus route free of charge. Simply use our search to find a coach that is best suited to your needs for your planned travel date.

What equipment is available for the Santiago Tuxtla Mexico City bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make travelling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Santiago Tuxtla to Mexico City on your planned travel date.

How does CheckMyBus find the best bus deals from Santiago Tuxtla to Mexico City?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 9 daily trips between Santiago Tuxtla and Mexico City. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Santiago Tuxtla to Mexico City?

Prices and availability for 9 trips between Santiago Tuxtla and Mexico City change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Santiago Tuxtla to Mexico City

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Santiago Tuxtla and to Mexico City

Here’s an overview of the most popular bus routes to Santiago Tuxtla and to Mexico City. Simply click on the connection of your choice, and you will find all the details about your bus route!