Bus tickets Santiago, RM to Santa Cruz, LI from £2

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Compare all timetables for the bus from Santiago, RM to Santa Cruz, LI

Here is a selection of the cheapest bus trips from the schedule from Santiago, RM to Santa Cruz, LI from various bus operators like FlixBus, Nueva Andimar Vip or Buses Transantin for the next days.

today
£5
tomorrow
Tuesday
£5
Wednesday
£5
Thursday
Friday
£5
Saturday

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Buses Transantin 3h 20m 12:30 Santiago, RM Sur Bus Station 15:50 Santa Cruz, LI Central Bus Station  Premium Economy £5
Buses Transantin 3h 20m 13:30 Santiago, RM Sur Bus Station 16:50 Santa Cruz, LI Central Bus Station  Premium Economy £5
FlixBus 2h 40m 13:59 Santiago, RM Sur Bus Station 16:39 Santa Cruz, LI Central Bus Station  Economy £5
FlixBus 2h 45m 16:59 Santiago, RM Sur Bus Station 19:44 Santa Cruz, LI Central Bus Station  Economy £5
Buses Jet Sur 3h 0m 10:45 Santiago, RM Sur Bus Station 13:45 Santa Cruz, LI Central Bus Station  Premium Economy £6
  • Did you know that if you travel from Santiago, RM to Santa Cruz, LI via Rancagua, you can save more than £1? You can find the corresponding connections below.
    • FlixBus
      2h 55m
      0
      06:00
      Santiago, RM
      Sur Bus Station
      07:00
      Rancagua
      Terminal O'Higgins
      0
      FlixBus
      Economy
      £1
      • Waiting Time 0h 20m
    • FlixBus
      1h 35m
      0
      07:20
      Rancagua
      Terminal O'Higgins
      08:55
      Santa Cruz, LI
      Central Bus Station
      0
      FlixBus
      Economy
      £3
    Travel time is 0h 15m longer, but you will save £1

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 2h 40m 06:15 Santiago, RM Sur Bus Station 08:55 Santa Cruz, LI Central Bus Station  Economy £5
FlixBus 2h 40m 08:59 Santiago, RM Sur Bus Station 11:39 Santa Cruz, LI Central Bus Station  Economy £5
FlixBus 2h 40m 09:59 Santiago, RM Sur Bus Station 12:39 Santa Cruz, LI Central Bus Station  Economy £5
FlixBus 2h 40m 10:59 Santiago, RM Sur Bus Station 13:39 Santa Cruz, LI Central Bus Station  Economy £5
FlixBus 2h 40m 11:29 Santiago, RM Sur Bus Station 14:09 Santa Cruz, LI Central Bus Station  Economy £5
  • Did you know that if you travel from Santiago, RM to Santa Cruz, LI via Rancagua, you can save more than £1? You can find the corresponding connections below.
    • FlixBus
      2h 55m
      0
      06:00
      Santiago, RM
      Sur Bus Station
      07:00
      Rancagua
      Terminal O'Higgins
      0
      FlixBus
      Economy
      £1
      • Waiting Time 0h 20m
    • FlixBus
      1h 35m
      0
      07:20
      Rancagua
      Terminal O'Higgins
      08:55
      Santa Cruz, LI
      Central Bus Station
      0
      FlixBus
      Economy
      £3
    Travel time is 0h 15m longer, but you will save £1

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 2h 40m 06:15 Santiago, RM Sur Bus Station 08:55 Santa Cruz, LI Central Bus Station  Economy £5
FlixBus 2h 40m 08:59 Santiago, RM Sur Bus Station 11:39 Santa Cruz, LI Central Bus Station  Economy £5
FlixBus 2h 40m 09:59 Santiago, RM Sur Bus Station 12:39 Santa Cruz, LI Central Bus Station  Economy £5
FlixBus 2h 40m 10:59 Santiago, RM Sur Bus Station 13:39 Santa Cruz, LI Central Bus Station  Economy £5
FlixBus 2h 40m 11:29 Santiago, RM Sur Bus Station 14:09 Santa Cruz, LI Central Bus Station  Economy £5
  • Did you know that if you travel from Santiago, RM to Santa Cruz, LI via Rancagua, you can save more than £1? You can find the corresponding connections below.
    • FlixBus
      2h 55m
      0
      06:00
      Santiago, RM
      Sur Bus Station
      07:00
      Rancagua
      Terminal O'Higgins
      0
      FlixBus
      Economy
      £1
      • Waiting Time 0h 20m
    • FlixBus
      1h 35m
      0
      07:20
      Rancagua
      Terminal O'Higgins
      08:55
      Santa Cruz, LI
      Central Bus Station
      0
      FlixBus
      Economy
      £3
    Travel time is 0h 15m longer, but you will save £1

Cheapest bus trips Friday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 2h 40m 06:15 Santiago, RM Sur Bus Station 08:55 Santa Cruz, LI Central Bus Station  Economy £5
FlixBus 2h 40m 08:59 Santiago, RM Sur Bus Station 11:39 Santa Cruz, LI Central Bus Station  Economy £5
FlixBus 2h 40m 09:59 Santiago, RM Sur Bus Station 12:39 Santa Cruz, LI Central Bus Station  Economy £5
FlixBus 2h 40m 10:59 Santiago, RM Sur Bus Station 13:39 Santa Cruz, LI Central Bus Station  Economy £6
FlixBus 2h 40m 11:29 Santiago, RM Sur Bus Station 14:09 Santa Cruz, LI Central Bus Station  Economy £6
  • Did you know that if you travel from Santiago, RM to Santa Cruz, LI via Rancagua, you can save more than £1? You can find the corresponding connections below.
    • FlixBus
      2h 55m
      0
      06:00
      Santiago, RM
      Sur Bus Station
      07:00
      Rancagua
      Terminal O'Higgins
      0
      FlixBus
      Economy
      £1
      • Waiting Time 0h 20m
    • FlixBus
      1h 35m
      0
      07:20
      Rancagua
      Terminal O'Higgins
      08:55
      Santa Cruz, LI
      Central Bus Station
      0
      FlixBus
      Economy
      £3
    Travel time is 0h 15m longer, but you will save £1

Best Price Offer: The price for the cheapest coach from Santiago, RM to Santa Cruz, LI is £2 on 15/12/2025. Flexible travellers save on ticket prices.


Frequency of bus connections between Santiago, RM and Santa Cruz, LI

See here how frequent the connections between Santiago, RM and Santa Cruz, LI are, during different times and days of the week.
Sunday is the busiest day, with more than 25 daily coaches from Santiago, RM to Santa Cruz, LI. Tuesday has instead the fewest connections, with only 14 daily coaches between Santiago, RM and Santa Cruz, LI.
The busiest time of the day is the Afternoon, with 26 coaches from Santiago, RM to Santa Cruz, LI, while Morning sees the fewest connections between Santiago, RM and Santa Cruz, LI, with 19 offers.

Facts about coaches from Santiago, RM to Santa Cruz, LI

Compare all providers like FlixBus, Nueva Andimar Vip and Buses Transantin that travel 16 times every day by bus from Santiago, RM to Santa Cruz, LI in one click! Book your bus ticket from Santiago, RM to Santa Cruz, LI starting from £2!

Cheapest Bus £2
Fastest Bus 2h 40m
Earliest Coach 10:45
Latest Coach 20:59
Daily Bus Connections 16 Ø
Distance 146.4 km
Coach Companies FlixBus, Nueva Andimar Vip, Buses Transantin and Buses Jet Sur

Cheapest coach connections from Santiago, RM to Santa Cruz, LI

Every day, 16 buses from 4 coach companies leave Santiago, RM for Santa Cruz, LI: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 21/12/2025 and for the following days.

Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday
Monday 15/12
Tuesday 16/12
Wednesday 17/12
Thursday 18/12
Friday 19/12
Saturday 20/12
Sunday 21/12
£5
Monday 22/12
Tuesday 23/12
£5
Wednesday 24/12
£5
Thursday 25/12
£5
Friday 26/12
£5
Saturday 27/12
£6
Sunday 28/12
£5
Monday 29/12
Tuesday 30/12
£5
Wednesday 31/12
£6
Thursday 01/01
Friday 02/01
£2
Saturday 03/01
Sunday 04/01
£5
Monday 05/01
Tuesday 06/01
£5
Wednesday 07/01
Thursday 08/01
Friday 09/01
£2
Saturday 10/01
£6
Sunday 11/01

The cheapest time to travel from Santiago, RM to Santa Cruz, LI

See here on which day and which time of the day you can find the cheapest bus ticket from Santiago, RM to Santa Cruz, LI, for the next 30 days.
With a price starting from £2, Friday is the cheapest day for a coach from Santiago, RM to Santa Cruz, LI. Sunday instead is the most expensive day with prices starting from £5.
Morning is the cheapest day time for bus tickets from Santiago, RM to Santa Cruz, LI, with £5. Morning is the most expensive time of the day with prices starting from £5.

How to save money travelling from Santiago, RM to Santa Cruz, LI

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Santiago, RM to Santa Cruz, LI in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Santiago, RM to Santa Cruz, LI, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Santiago, RM to Santa Cruz, LI are also emptier.

All bus stations and stops in Santiago, RM and Santa Cruz, LI

The map below shows you where to find all the bus stations in Santiago, RM and Santa Cruz, LI.

Service and Comfort on the bus from Santiago, RM to Santa Cruz, LI

Want to know which seat classes are available on the coaches from Santiago, RM to Santa Cruz, LI? Or which bus companies serve the route Santiago, RM to Santa Cruz, LI? Below you will find answers to your questions.

FAQs about the Santiago, RM to Santa Cruz, LI bus

How much does a Santiago, RM - Santa Cruz, LI coach trip cost?

This depends on, among other things, the day and travel time. The cheapest ticket for the Santiago, RM - Santa Cruz, LI bus trip is available from £2 and takes 2h 40m. Compare offers and save money!

How much could I save by comparing buses from Santiago, RM to Santa Cruz, LI?

The connection Santiago, RM to Santa Cruz, LI is offered by 4 companies with ticket prices ranging from £2 to £8. Therefore, we suggest booking your ticket as soon as possible to ensure you will get the cheapest ticket price.

How many connections are available for the Santiago, RM - Santa Cruz, LI route on average every day?

Each day, the bus route from Santiago, RM to Santa Cruz, LI is offered by roughly 16 busses. By using our search, you can compare bus schedules and find your ideal trip.

How long does a bus to Santa Cruz, LI from Santiago, RM take?

The quickest coach from Santiago, RM to Santa Cruz, LI is provided by Nueva Andimar Vip and takes 2h 40m. Coach tickets for this connection cost £6. However, keep in mind that the connection can take longer due to traffic.

What time is the first bus from Santiago, RM to Santa Cruz, LI?

The earliest bus to Santa Cruz, LI departs from Santiago, RM at 10:45. In this context, information about departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

What time is the last coach from Santiago, RM to Santa Cruz, LI?

The latest bus to Santa Cruz, LI departs from Santiago, RM at 20:59. Please note that departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

Which bus companies serve the Santiago, RM - Santa Cruz, LI route?

Passengers looking to travel from Santiago, RM to Santa Cruz, LI can travel with FlixBus, Nueva Andimar Vip and Buses Transantin. Compare all available bus tickets with our search to book the trip that works best for you.

Is there a direct bus between Santiago, RM and Santa Cruz, LI?

You can check all the direct connections between Santiago, RM and Santa Cruz, LI by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus, Nueva Andimar Vip and Buses Transantin.

What can I take with me on the bus to Santa Cruz, LI from Santiago, RM?

Depending on which provider you travel with, what you are allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the bus for the Santiago, RM Santa Cruz, LI bus route free of charge. Simply use our search to find a coach that is best suited to your needs for your planned travel date.

What equipment is available for the Santiago, RM Santa Cruz, LI bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make travelling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Santiago, RM to Santa Cruz, LI on your planned travel date.

How does CheckMyBus find the best bus deals from Santiago, RM to Santa Cruz, LI?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 16 daily trips between Santiago, RM and Santa Cruz, LI. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Santiago, RM to Santa Cruz, LI?

Prices and availability for 16 trips between Santiago, RM and Santa Cruz, LI change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Santiago, RM to Santa Cruz, LI

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

Premium Economy
PremiumEconomy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

More bus routes to Santiago, RM and to Santa Cruz, LI

Here’s an overview of the most popular bus routes to Santiago, RM and to Santa Cruz, LI. Simply click on the connection of your choice, and you will find all the details about your bus route!
Coach Buenos Aires to Santa Cruz, LI Coach Buenos Aires to Santa Cruz, LI
Coach from Viña del Mar to Santiago, RM Coach from Viña del Mar to Santiago, RM
Bus to Santiago, RM from Calama Bus to Santiago, RM from Calama
Coaches Coquimbo to Santiago, RM Coaches Coquimbo to Santiago, RM
Buses Copiapó to Santiago, RM Buses Copiapó to Santiago, RM
Bus to Santiago, RM from Villarrica (CL) Bus to Santiago, RM from Villarrica (CL)
Bus to Santiago, RM from Lautaro Bus to Santiago, RM from Lautaro
Coach Vallenar to Santiago, RM Coach Vallenar to Santiago, RM
Los Vilos to Santiago, RM coach Los Vilos to Santiago, RM coach
Bus to Santiago, RM from Nueva Imperial Bus to Santiago, RM from Nueva Imperial
Pitrufquén to Santiago, RM bus Pitrufquén to Santiago, RM bus
Buses Curicó to Santiago, RM Buses Curicó to Santiago, RM
Coaches Angol to Santiago, RM Coaches Angol to Santiago, RM
Coach to Santiago, RM from Coronel Coach to Santiago, RM from Coronel
Bus Quintero to Santiago, RM Bus Quintero to Santiago, RM
Coach Tocopilla to Santiago, RM Coach Tocopilla to Santiago, RM
Curacautin to Santiago, RM bus Curacautin to Santiago, RM bus
Bus to Santiago, RM from Los Andes Bus to Santiago, RM from Los Andes
Coach Matanzas to Santiago, RM Coach Matanzas to Santiago, RM
Coach from Loncoche to Santiago, RM Coach from Loncoche to Santiago, RM
Bus Collipulli to Santiago, RM Bus Collipulli to Santiago, RM
Coach from Saavedra to Santiago, RM Coach from Saavedra to Santiago, RM
Bus Pichicuy to Santiago, RM Bus Pichicuy to Santiago, RM
Bus from Arica, AP to Santiago, RM Bus from Arica, AP to Santiago, RM
Popular Airport Transfers to Santiago, RM and to Santa Cruz, LI
CheckMyBus › Coaches in Chile › Coach to Santiago, RM › Coach to Santa Cruz, LI

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