Bus and Coach from San Diego to San Antonio, TX: Compare all prices

Compare all timetables for the bus from San Diego to San Antonio, TX

Here is a selection of the cheapest bus trips from the schedule from San Diego to San Antonio, TX from various bus operators like FlixBus or Greyhound US for the next days.

today

tomorrow

Tuesday

£155

Wednesday

Thursday

£165

Friday

Saturday

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	39h 40m	06:45	San Diego	Old Town Transit Center	00:25	San Antonio, TX	Coach Station	Economy	£155	A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 16/12/2025 06:45:00 to Coach Station, San Antonio, TX (USA) arriving at 18/12/2025 00:25:00. 50 Economy ticket for £155 per person are available. Travel duration is 39h 40m
FlixBus	32h 15m	14:10	San Diego	La Jolla Village	00:25	San Antonio, TX	Coach Station	Economy	£155	A Bus from FlixBus goes from La Jolla Village, San Diego (USA) at 16/12/2025 14:10:00 to Coach Station, San Antonio, TX (USA) arriving at 18/12/2025 00:25:00. 50 Economy ticket for £155 per person are available. Travel duration is 32h 15m
FlixBus	37h 0m	09:25	San Diego	Old Town Transit Center	00:25	San Antonio, TX	Coach Station	Economy	£156	A Bus from FlixBus goes from Old Town Transit Center, San Diego (USA) at 16/12/2025 09:25:00 to Coach Station, San Antonio, TX (USA) arriving at 18/12/2025 00:25:00. 50 Economy ticket for £156 per person are available. Travel duration is 37h 0m
FlixBus	32h 40m	13:45	San Diego	Seaport Village	00:25	San Antonio, TX	Coach Station	Economy	£156	A Bus from FlixBus goes from Seaport Village, San Diego (USA) at 16/12/2025 13:45:00 to Coach Station, San Antonio, TX (USA) arriving at 18/12/2025 00:25:00. 50 Economy ticket for £156 per person are available. Travel duration is 32h 40m
Greyhound US	39h 20m	19:35	San Diego	Old Town Transit Center	12:55	San Antonio, TX	Coach Station	Economy	£181	A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 16/12/2025 19:35:00 to Coach Station, San Antonio, TX (USA) arriving at 18/12/2025 12:55:00. 50 Economy ticket for £181 per person are available. Travel duration is 39h 20m

Did you know that if you travel from San Diego to San Antonio, TX via Calexico, CA, you can save more than £35? You can find the corresponding connections below.
- Busbud
  
  36h 25m
  
  0
  
  10:00
  
  San Diego
  Old Town Transit Center
  
  12:35
  
  Calexico, CA
  Coach Station
  
  0
  
  Economy
  
  £15
  
  A Bus from Busbud goes from Old Town Transit Center, San Diego (USA) at 18/12/2025 10:00:00 to Coach Station, Calexico, CA (USA) arriving at 18/12/2025 12:35:00. 50 Economy ticket for £15 per person are available. Travel duration is 2h 35m
- FlixBus
  
  28h 20m
  
  0
  
  18:05
  
  Calexico, CA
  Coach Station
  
  00:25
  
  San Antonio, TX
  Coach Station
  
  0
  
  Economy
  
  £105
  
  A Bus from FlixBus goes from Coach Station, Calexico, CA (USA) at 18/12/2025 18:05:00 to Coach Station, San Antonio, TX (USA) arriving at 20/12/2025 00:25:00. 50 Economy ticket for £105 per person are available. Travel duration is 28h 20m
Travel time is 2h 10m longer, but you will save £35

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	32h 15m	14:10	San Diego	La Jolla Village	00:25	San Antonio, TX	Coach Station	Economy	£165	A Bus from FlixBus goes from La Jolla Village, San Diego (USA) at 18/12/2025 14:10:00 to Coach Station, San Antonio, TX (USA) arriving at 20/12/2025 00:25:00. 50 Economy ticket for £165 per person are available. Travel duration is 32h 15m
FlixBus	37h 0m	09:25	San Diego	Old Town Transit Center	00:25	San Antonio, TX	Coach Station	Economy	£166	A Bus from FlixBus goes from Old Town Transit Center, San Diego (USA) at 18/12/2025 09:25:00 to Coach Station, San Antonio, TX (USA) arriving at 20/12/2025 00:25:00. 50 Economy ticket for £166 per person are available. Travel duration is 37h 0m
FlixBus	32h 40m	13:45	San Diego	Seaport Village	00:25	San Antonio, TX	Coach Station	Economy	£166	A Bus from FlixBus goes from Seaport Village, San Diego (USA) at 18/12/2025 13:45:00 to Coach Station, San Antonio, TX (USA) arriving at 20/12/2025 00:25:00. 50 Economy ticket for £166 per person are available. Travel duration is 32h 40m
Greyhound US	35h 55m	10:00	San Diego	Old Town Transit Center	23:55	San Antonio, TX	Coach Station	Economy	£209	A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 18/12/2025 10:00:00 to Coach Station, San Antonio, TX (USA) arriving at 19/12/2025 23:55:00. 50 Economy ticket for £209 per person are available. Travel duration is 35h 55m
Greyhound US	39h 20m	19:35	San Diego	Old Town Transit Center	12:55	San Antonio, TX	Coach Station	Economy	£222	A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 18/12/2025 19:35:00 to Coach Station, San Antonio, TX (USA) arriving at 20/12/2025 12:55:00. 50 Economy ticket for £222 per person are available. Travel duration is 39h 20m

Did you know that if you travel from San Diego to San Antonio, TX via Calexico, CA, you can save more than £45? You can find the corresponding connections below.
- Busbud
  
  36h 25m
  
  0
  
  10:00
  
  San Diego
  Old Town Transit Center
  
  12:35
  
  Calexico, CA
  Coach Station
  
  0
  
  Economy
  
  £15
  
  A Bus from Busbud goes from Old Town Transit Center, San Diego (USA) at 18/12/2025 10:00:00 to Coach Station, Calexico, CA (USA) arriving at 18/12/2025 12:35:00. 50 Economy ticket for £15 per person are available. Travel duration is 2h 35m
- FlixBus
  
  28h 20m
  
  0
  
  18:05
  
  Calexico, CA
  Coach Station
  
  00:25
  
  San Antonio, TX
  Coach Station
  
  0
  
  Economy
  
  £105
  
  A Bus from FlixBus goes from Coach Station, Calexico, CA (USA) at 18/12/2025 18:05:00 to Coach Station, San Antonio, TX (USA) arriving at 20/12/2025 00:25:00. 50 Economy ticket for £105 per person are available. Travel duration is 28h 20m
Travel time is 2h 10m longer, but you will save £45

Best Price Offer: The price for the cheapest coach from San Diego to San Antonio, TX is £155 on 16/12/2025. Flexible travellers save on ticket prices.

Frequency of bus connections between San Diego and San Antonio, TX

See here how frequent the connections between San Diego and San Antonio, TX are, during different times and days of the week.

Thursday is the busiest day, with more than 9 daily coaches from San Diego to San Antonio, TX. Tuesday has instead the fewest connections, with only 7 daily coaches between San Diego and San Antonio, TX.

The busiest time of the day is the Morning, with 8 coaches from San Diego to San Antonio, TX, while Evening sees the fewest connections between San Diego and San Antonio, TX, with 2 offers.

Facts about coaches from San Diego to San Antonio, TX

Compare all providers like FlixBus and Greyhound US that travel 8 times every day by bus from San Diego to San Antonio, TX in one click! Book your bus ticket from San Diego to San Antonio, TX starting from £155!

Cheapest Bus	£155
Fastest Bus	34h 15m
Earliest Coach	06:45
Latest Coach	19:35
Daily Bus Connections	8 Ø
Distance	1,812.4 km
Coach Companies	FlixBus and Greyhound US

Cheapest coach connections from San Diego to San Antonio, TX

Every day, 8 buses from 2 coach companies leave San Diego for San Antonio, TX: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 14/12/2025 and for the following days.

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday

Monday 08/12

Tuesday 09/12

Wednesday 10/12

Thursday 11/12

Friday 12/12

Saturday 13/12

Sunday 14/12

Monday 15/12

Tuesday 16/12

£155

Wednesday 17/12

Thursday 18/12

£165

Friday 19/12

Saturday 20/12

Sunday 21/12

£185

Monday 22/12

Tuesday 23/12

£166

Wednesday 24/12

Thursday 25/12

Friday 26/12

Saturday 27/12

Sunday 28/12

Monday 29/12

Tuesday 30/12

Wednesday 31/12

Thursday 01/01

Friday 02/01

Saturday 03/01

Sunday 04/01

The cheapest time to travel from San Diego to San Antonio, TX

See here on which day and which time of the day you can find the cheapest bus ticket from San Diego to San Antonio, TX, for the next 30 days.

With a price starting from £155, Tuesday is the cheapest day for a coach from San Diego to San Antonio, TX. Thursday instead is the most expensive day with prices starting from £165.

Morning is the cheapest day time for bus tickets from San Diego to San Antonio, TX, with £155. Evening is the most expensive time of the day with prices starting from £181.

How to save money travelling from San Diego to San Antonio, TX

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from San Diego to San Antonio, TX in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from San Diego to San Antonio, TX, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from San Diego to San Antonio, TX are also emptier.

All bus stations and stops in San Diego and San Antonio, TX

The map below shows you where to find all the bus stations in San Diego and San Antonio, TX.

Old Town Transit Center

Congress Street 2727

San Ysidro Transit Center

E San Ysidro Blvd 723

Santa Fe Depot

Kettner Blvd 1050

Seaport Village

W Harbor Dr 789

La Jolla Village

Hyatt Regency

Coach Station

N St Mary's St 500

San Antonio

Pearl District

Avenue A 699-599

W. Southcross & Buffalo Bus Stop

Commerce & Bowie Bus Stop

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from San Diego to San Antonio, TX? Compare all modes of transports from San Diego to San Antonio, TX.

Service and Comfort on the bus from San Diego to San Antonio, TX

Want to know which seat classes are available on the coaches from San Diego to San Antonio, TX? Or which bus companies serve the route San Diego to San Antonio, TX? Below you will find answers to your questions.

FAQs about the San Diego to San Antonio, TX bus

How much does a San Diego - San Antonio, TX coach trip cost?

This depends on, among other things, the day and travel time. The cheapest ticket for the San Diego - San Antonio, TX bus trip is available from £155 and takes 41h 40m. Compare offers and save money!

How much could I save by comparing buses from San Diego to San Antonio, TX?

The connection San Diego to San Antonio, TX is offered by 2 companies with ticket prices ranging from £155 to £222. Therefore, we suggest booking your ticket as soon as possible to ensure you will get the cheapest ticket price.

How many connections are available for the San Diego - San Antonio, TX route on average every day?

Each day, the bus route from San Diego to San Antonio, TX is offered by roughly 8 busses. By using our search, you can compare bus schedules and find your ideal trip.

How long does a bus to San Antonio, TX from San Diego take?

The quickest coach from San Diego to San Antonio, TX is provided by FlixBus and takes 34h 15m. Coach tickets for this connection cost £155. However, keep in mind that the connection can take longer due to traffic.

What time is the first bus from San Diego to San Antonio, TX?

The earliest bus to San Antonio, TX departs from San Diego at 06:45. In this context, information about departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

What time is the last coach from San Diego to San Antonio, TX?

The latest bus to San Antonio, TX departs from San Diego at 19:35. Please note that departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

Which bus companies serve the San Diego - San Antonio, TX route?

Passengers looking to travel from San Diego to San Antonio, TX can travel with FlixBus and Greyhound US. Compare all available bus tickets with our search to book the trip that works best for you.

Is there a direct bus between San Diego and San Antonio, TX?

You can check all the direct connections between San Diego and San Antonio, TX by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the bus to San Antonio, TX from San Diego?

Depending on which provider you travel with, what you are allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the bus for the San Diego San Antonio, TX bus route free of charge. Simply use our search to find a coach that is best suited to your needs for your planned travel date.

What equipment is available for the San Diego San Antonio, TX bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make travelling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from San Diego to San Antonio, TX on your planned travel date.

Available seat classes which are offered on the bus route San Diego to San Antonio, TX

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to San Diego and to San Antonio, TX

Here’s an overview of the most popular bus routes to San Diego and to San Antonio, TX. Simply click on the connection of your choice, and you will find all the details about your bus route!