Coach Rome to Siracusa from £36

Which bus from Rome to Siracusa is the best?

Check the bus schedule for Rome to Siracusa. Here is a selection of the cheapest coach trips for the next days from bus operators like FlixBus. To see the full timetable for all coaches just use or search and compare.

today

tomorrow

Monday

Tuesday

£57

Wednesday

Thursday

Friday

£56

Cheapest bus trips Tuesday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	12h 15m	21:00	Rome	Tiburtina Bus Station	09:15	Siracusa	Corso Umberto Bus Station		Economy	£57	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 03/11/2026 21:00:00 to Corso Umberto Bus Station, Siracusa (Italy) arriving at 04/11/2026 09:15:00. 50 Economy ticket for £57 per person are available. Travel duration is 12h 15m

Did you know that if you travel from Rome to Siracusa via Messina, you can save more than £47? You can find the corresponding connections below.
- Interbus
  
  14h 35m
  
  0
  
  06:05
  
  Rome
  Appia/Quarto Miglio
  
  07:30
  
  Messina
  Central Station
  
  0
  
  Economy
  
  £2
  
  A Bus from Interbus goes from Appia/Quarto Miglio, Rome (Italy) at 04/11/2026 06:05:00 to Central Station, Messina (Italy) arriving at 04/11/2026 07:30:00. 50 Economy ticket for £2 per person are available. Travel duration is 1h 25m
- FlixBus
  
  2h 40m
  
  0
  
  18:00
  
  Messina
  Piazza della Repubblica
  
  20:40
  
  Siracusa
  Corso Umberto Bus Station
  
  0
  
  Economy
  
  £8
  
  A Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 04/11/2026 18:00:00 to Corso Umberto Bus Station, Siracusa (Italy) arriving at 04/11/2026 20:40:00. 50 Economy ticket for £8 per person are available. Travel duration is 2h 40m
Travel time is 2h 20m longer, but you will save £47

Cheapest bus trips Friday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	12h 15m	21:00	Rome	Tiburtina Bus Station	09:15	Siracusa	Corso Umberto Bus Station		Economy	£56	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 06/11/2026 21:00:00 to Corso Umberto Bus Station, Siracusa (Italy) arriving at 07/11/2026 09:15:00. 50 Economy ticket for £56 per person are available. Travel duration is 12h 15m

Did you know that if you travel from Rome to Siracusa via Messina, you can save more than £46? You can find the corresponding connections below.
- Interbus
  
  14h 35m
  
  0
  
  06:05
  
  Rome
  Appia/Quarto Miglio
  
  07:30
  
  Messina
  Central Station
  
  0
  
  Economy
  
  £2
  
  A Bus from Interbus goes from Appia/Quarto Miglio, Rome (Italy) at 04/11/2026 06:05:00 to Central Station, Messina (Italy) arriving at 04/11/2026 07:30:00. 50 Economy ticket for £2 per person are available. Travel duration is 1h 25m
- FlixBus
  
  2h 40m
  
  0
  
  18:00
  
  Messina
  Piazza della Repubblica
  
  20:40
  
  Siracusa
  Corso Umberto Bus Station
  
  0
  
  Economy
  
  £8
  
  A Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 04/11/2026 18:00:00 to Corso Umberto Bus Station, Siracusa (Italy) arriving at 04/11/2026 20:40:00. 50 Economy ticket for £8 per person are available. Travel duration is 2h 40m
Travel time is 2h 20m longer, but you will save £46

Best Price Offer: The price for the cheapest coach from Rome to Siracusa is £36 on 04/11/2026. Flexible travellers save on ticket prices.

All facts for Rome to Siracusa bus at a glance

Compare all coach operators like FlixBus that travel daily 1 times by bus from Rome to Siracusa in one click. Book your Rome to Siracusa bus ticket starting from £36!

Cheapest Bus	£36
Fastest Bus	12h 15m
Earliest Coach	21:00
Latest Coach	21:00
Daily Bus Connections	1 Ø
Distance	587.5 km
Coach Companies	FlixBus

What are the cheapest coach tickets from Rome to Siracusa?

Every day, 1 buses from 1 coach companies leave Rome for Siracusa. Check the table below to find the cheapest prices for coach tickets for this route, starting from 31/10/2026 and for the following days. Make sure get the cheapest bus ticket!

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday

Monday 26/10

Tuesday 27/10

Wednesday 28/10

Thursday 29/10

Friday 30/10

Saturday 31/10

£44

Sunday 01/11

Monday 02/11

£47

Tuesday 03/11

£57

Wednesday 04/11

£36

Thursday 05/11

Friday 06/11

£56

Saturday 07/11

£39

Sunday 08/11

£65

Monday 09/11

Tuesday 10/11

Wednesday 11/11

Thursday 12/11

Friday 13/11

Saturday 14/11

Sunday 15/11

Monday 16/11

£51

Tuesday 17/11

£53

Wednesday 18/11

£54

Thursday 19/11

£64

Friday 20/11

Saturday 21/11

Sunday 22/11

How to save money travelling from Rome to Siracusa

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying higher prices for your trip? Plan your bus trips smartly. Here are a few hacks to save money on your coach journey.

Book the ticket from Rome to Siracusa in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the coach from Rome to Siracusa, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Rome to Siracusa are also emptier.

Check for bus deals and promotions for all bus companies in this route. On CheckMyBus we show special offers directly in the coach trip on our search. Sign-up and check or deals sections and get notifications on our latest travel hacks.

All bus stations and stops in Rome and Siracusa

Here is a map with all coach stations in Rome and Siracusa. Compare which stop is closest to your destination to save time to find the fastest buses and connections.

Anagnina Bus Station

Piazzale della Stazione Anagnina

Termini Bus Station

Piazza dei Cinquecento 64

Tiburtina Bus Station

Largo Guido Mazzoni 4

Tiburtina Coach Station

Tiburtina Partenze

Vatican City

Via Crescenzio 19

Corso Umberto Bus Station

Corso Umberto 196

Scala Greca Coach Station

Viale Scala Greca 246

Corso Gelone

Corso Gelone 50

Via Von Platen

Fontane Bianche

All you need to know when you travel by bus from Rome to Siracusa

Check all information on comfort and services on the coaches from Rome to Siracusa. Which seat classes are available or what are the amenities of operators on your coach trip? Below you´ll find answers to your questions.

FAQs for Rome to Siracusa bus

How much does a Rome Siracusa coach trip cost?

This depends on, among other things, the day and travel time. The cheapest ticket for the Rome Siracusa bus trip is available from £36 and takes 12h 15m. Compare offers and save money!

How much could I save by comparing buses from Rome to Siracusa?

This connection is offered by 1 companies with ticket prices ranging from £36 to £57. Therefore, we suggest booking your ticket as soon as possible to ensure you’ll get the cheapest bus trip to Siracusa.

How many connections are available for the Rome Siracusa route on average every day?

Each day, the bus route from Rome to Siracusa is offered by roughly 1 busses. By using our search, you can compare bus schedules and find your ideal trip.

How long does a bus to Siracusa from Rome take?

The quickest coach from Rome to Siracusa is provided by FlixBus and takes 12h 15m. Coach tickets for this connection cost £57. However, keep in mind that the connection can take longer due to traffic.

What time is the first bus from Rome to Siracusa?

The earliest bus to Siracusa departs from Rome at 21:00. In this context, information about departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

What time is the last coach from Rome to Siracusa?

The latest bus to Siracusa departs from Rome at 21:00. Please note that departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

Which bus companies serve the Rome Siracusa route?

Passengers looking to travel from Rome to Siracusa can travel with FlixBus. Compare all available bus tickets with our search to book the trip that works best for you.

Is there a direct bus between Rome and Siracusa?

You can check all the direct connections between Rome and Siracusa by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus.

What can I take with me on the bus to Siracusa from Rome?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the bus for the Rome Siracusa bus route free of charge. Simply use our search to find a coach that is best suited to your needs for your planned travel date.

What equipment is available for the Rome Siracusa bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make travelling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Rome to Siracusa on your planned travel date.

How does CheckMyBus find the best coach deals from Rome to Siracusa?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 1 daily trips between Rome and Siracusa. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Rome to Siracusa?

Prices and availability for 1 trips between Rome and Siracusa change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Rome to Siracusa

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Rome and to Siracusa

Here’s an overview of the most popular bus routes to Rome and to Siracusa. Simply click on the connection of your choice, and you’ll find all the details about your bus route!