Bus and Coach from Prague to Karlsruhe: Compare all prices

Compare all timetables for the bus from Prague to Karlsruhe

Here is a selection of the cheapest bus trips from the schedule from Prague to Karlsruhe from various bus operators like FlixBus for the next days.

today

£27

tomorrow

£23

Tuesday

£24

Wednesday

£24

Thursday

£22

Friday

£25

Saturday

£26

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	8h 35m	22:00	Prague	ÚAN Florenc	06:35	Karlsruhe	Central Station	Economy	£27	A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 04/10/2026 22:00:00 to Central Station, Karlsruhe (Germany) arriving at 05/10/2026 06:35:00. 50 Economy ticket for £27 per person are available. Travel duration is 8h 35m
FlixBus	8h 10m	22:25	Prague	Hradčanská	06:35	Karlsruhe	Central Station	Economy	£27	A Bus from FlixBus goes from Hradčanská, Prague (Czech Republic) at 04/10/2026 22:25:00 to Central Station, Karlsruhe (Germany) arriving at 05/10/2026 06:35:00. 50 Economy ticket for £27 per person are available. Travel duration is 8h 10m
FlixBus	8h 40m	15:10	Prague	ÚAN Florenc	23:50	Karlsruhe	Central Station	Economy	£35	A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 04/10/2026 15:10:00 to Central Station, Karlsruhe (Germany) arriving at 04/10/2026 23:50:00. 50 Economy ticket for £35 per person are available. Travel duration is 8h 40m
FlixBus	9h 20m	14:30	Prague	Černý Most	23:50	Karlsruhe	Central Station	Economy	£35	A Bus from FlixBus goes from Černý Most, Prague (Czech Republic) at 04/10/2026 14:30:00 to Central Station, Karlsruhe (Germany) arriving at 04/10/2026 23:50:00. 50 Economy ticket for £35 per person are available. Travel duration is 9h 20m
FlixBus	10h 35m	09:00	Prague	Wilsonova Coach Station	19:35	Karlsruhe	Central Station	Economy	£39	A Bus from FlixBus goes from Wilsonova Coach Station, Prague (Czech Republic) at 04/10/2026 09:00:00 to Central Station, Karlsruhe (Germany) arriving at 04/10/2026 19:35:00. 50 Economy ticket for £39 per person are available. Travel duration is 10h 35m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	8h 40m	15:10	Prague	ÚAN Florenc	23:50	Karlsruhe	Central Station	Economy	£23	A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 05/10/2026 15:10:00 to Central Station, Karlsruhe (Germany) arriving at 05/10/2026 23:50:00. 50 Economy ticket for £23 per person are available. Travel duration is 8h 40m
FlixBus	9h 20m	14:30	Prague	Černý Most	23:50	Karlsruhe	Central Station	Economy	£23	A Bus from FlixBus goes from Černý Most, Prague (Czech Republic) at 05/10/2026 14:30:00 to Central Station, Karlsruhe (Germany) arriving at 05/10/2026 23:50:00. 50 Economy ticket for £23 per person are available. Travel duration is 9h 20m
FlixBus	8h 35m	22:00	Prague	ÚAN Florenc	06:35	Karlsruhe	Central Station	Economy	£24	A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 05/10/2026 22:00:00 to Central Station, Karlsruhe (Germany) arriving at 06/10/2026 06:35:00. 50 Economy ticket for £24 per person are available. Travel duration is 8h 35m
FlixBus	8h 10m	22:25	Prague	Hradčanská	06:35	Karlsruhe	Central Station	Economy	£24	A Bus from FlixBus goes from Hradčanská, Prague (Czech Republic) at 05/10/2026 22:25:00 to Central Station, Karlsruhe (Germany) arriving at 06/10/2026 06:35:00. 50 Economy ticket for £24 per person are available. Travel duration is 8h 10m
FlixBus	8h 50m	13:05	Prague	Wilsonova Coach Station	21:55	Karlsruhe	Central Station	Economy	£28	A Bus from FlixBus goes from Wilsonova Coach Station, Prague (Czech Republic) at 05/10/2026 13:05:00 to Central Station, Karlsruhe (Germany) arriving at 05/10/2026 21:55:00. 50 Economy ticket for £28 per person are available. Travel duration is 8h 50m

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	8h 40m	15:10	Prague	ÚAN Florenc	23:50	Karlsruhe	Central Station	Economy	£24	A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 06/10/2026 15:10:00 to Central Station, Karlsruhe (Germany) arriving at 06/10/2026 23:50:00. 50 Economy ticket for £24 per person are available. Travel duration is 8h 40m
FlixBus	9h 20m	14:30	Prague	Černý Most	23:50	Karlsruhe	Central Station	Economy	£24	A Bus from FlixBus goes from Černý Most, Prague (Czech Republic) at 06/10/2026 14:30:00 to Central Station, Karlsruhe (Germany) arriving at 06/10/2026 23:50:00. 50 Economy ticket for £24 per person are available. Travel duration is 9h 20m
FlixBus	8h 35m	22:00	Prague	ÚAN Florenc	06:35	Karlsruhe	Central Station	Economy	£25	A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 06/10/2026 22:00:00 to Central Station, Karlsruhe (Germany) arriving at 07/10/2026 06:35:00. 50 Economy ticket for £25 per person are available. Travel duration is 8h 35m
FlixBus	8h 10m	22:25	Prague	Hradčanská	06:35	Karlsruhe	Central Station	Economy	£25	A Bus from FlixBus goes from Hradčanská, Prague (Czech Republic) at 06/10/2026 22:25:00 to Central Station, Karlsruhe (Germany) arriving at 07/10/2026 06:35:00. 50 Economy ticket for £25 per person are available. Travel duration is 8h 10m
FlixBus	10h 50m	10:30	Prague	ÚAN Florenc	21:20	Karlsruhe	Central Station	Economy	£28	A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 06/10/2026 10:30:00 to Central Station, Karlsruhe (Germany) arriving at 06/10/2026 21:20:00. 50 Economy ticket for £28 per person are available. Travel duration is 10h 50m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	8h 40m	15:10	Prague	ÚAN Florenc	23:50	Karlsruhe	Central Station	Economy	£24	A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 07/10/2026 15:10:00 to Central Station, Karlsruhe (Germany) arriving at 07/10/2026 23:50:00. 50 Economy ticket for £24 per person are available. Travel duration is 8h 40m
FlixBus	9h 20m	14:30	Prague	Černý Most	23:50	Karlsruhe	Central Station	Economy	£24	A Bus from FlixBus goes from Černý Most, Prague (Czech Republic) at 07/10/2026 14:30:00 to Central Station, Karlsruhe (Germany) arriving at 07/10/2026 23:50:00. 50 Economy ticket for £24 per person are available. Travel duration is 9h 20m
FlixBus	8h 35m	22:00	Prague	ÚAN Florenc	06:35	Karlsruhe	Central Station	Economy	£25	A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 07/10/2026 22:00:00 to Central Station, Karlsruhe (Germany) arriving at 08/10/2026 06:35:00. 50 Economy ticket for £25 per person are available. Travel duration is 8h 35m
FlixBus	8h 10m	22:25	Prague	Hradčanská	06:35	Karlsruhe	Central Station	Economy	£25	A Bus from FlixBus goes from Hradčanská, Prague (Czech Republic) at 07/10/2026 22:25:00 to Central Station, Karlsruhe (Germany) arriving at 08/10/2026 06:35:00. 50 Economy ticket for £25 per person are available. Travel duration is 8h 10m
FlixBus	8h 50m	13:05	Prague	Wilsonova Coach Station	21:55	Karlsruhe	Central Station	Economy	£28	A Bus from FlixBus goes from Wilsonova Coach Station, Prague (Czech Republic) at 07/10/2026 13:05:00 to Central Station, Karlsruhe (Germany) arriving at 07/10/2026 21:55:00. 50 Economy ticket for £28 per person are available. Travel duration is 8h 50m

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	8h 35m	06:40	Prague	ÚAN Florenc	15:15	Karlsruhe	Central Station	Economy	£22	A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 08/10/2026 06:40:00 to Central Station, Karlsruhe (Germany) arriving at 08/10/2026 15:15:00. 50 Economy ticket for £22 per person are available. Travel duration is 8h 35m
FlixBus	8h 40m	15:10	Prague	ÚAN Florenc	23:50	Karlsruhe	Central Station	Economy	£22	A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 08/10/2026 15:10:00 to Central Station, Karlsruhe (Germany) arriving at 08/10/2026 23:50:00. 50 Economy ticket for £22 per person are available. Travel duration is 8h 40m
FlixBus	8h 35m	22:00	Prague	ÚAN Florenc	06:35	Karlsruhe	Central Station	Economy	£22	A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 08/10/2026 22:00:00 to Central Station, Karlsruhe (Germany) arriving at 09/10/2026 06:35:00. 50 Economy ticket for £22 per person are available. Travel duration is 8h 35m
FlixBus	9h 20m	14:30	Prague	Černý Most	23:50	Karlsruhe	Central Station	Economy	£22	A Bus from FlixBus goes from Černý Most, Prague (Czech Republic) at 08/10/2026 14:30:00 to Central Station, Karlsruhe (Germany) arriving at 08/10/2026 23:50:00. 50 Economy ticket for £22 per person are available. Travel duration is 9h 20m
FlixBus	8h 10m	22:25	Prague	Hradčanská	06:35	Karlsruhe	Central Station	Economy	£22	A Bus from FlixBus goes from Hradčanská, Prague (Czech Republic) at 08/10/2026 22:25:00 to Central Station, Karlsruhe (Germany) arriving at 09/10/2026 06:35:00. 50 Economy ticket for £22 per person are available. Travel duration is 8h 10m

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	8h 35m	06:40	Prague	ÚAN Florenc	15:15	Karlsruhe	Central Station	Economy	£25	A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 09/10/2026 06:40:00 to Central Station, Karlsruhe (Germany) arriving at 09/10/2026 15:15:00. 50 Economy ticket for £25 per person are available. Travel duration is 8h 35m
FlixBus	8h 35m	22:00	Prague	ÚAN Florenc	06:35	Karlsruhe	Central Station	Economy	£26	A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 09/10/2026 22:00:00 to Central Station, Karlsruhe (Germany) arriving at 10/10/2026 06:35:00. 50 Economy ticket for £26 per person are available. Travel duration is 8h 35m
FlixBus	8h 10m	22:25	Prague	Hradčanská	06:35	Karlsruhe	Central Station	Economy	£26	A Bus from FlixBus goes from Hradčanská, Prague (Czech Republic) at 09/10/2026 22:25:00 to Central Station, Karlsruhe (Germany) arriving at 10/10/2026 06:35:00. 50 Economy ticket for £26 per person are available. Travel duration is 8h 10m
FlixBus	8h 40m	15:10	Prague	ÚAN Florenc	23:50	Karlsruhe	Central Station	Economy	£27	A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 09/10/2026 15:10:00 to Central Station, Karlsruhe (Germany) arriving at 09/10/2026 23:50:00. 50 Economy ticket for £27 per person are available. Travel duration is 8h 40m
FlixBus	9h 20m	14:30	Prague	Černý Most	23:50	Karlsruhe	Central Station	Economy	£27	A Bus from FlixBus goes from Černý Most, Prague (Czech Republic) at 09/10/2026 14:30:00 to Central Station, Karlsruhe (Germany) arriving at 09/10/2026 23:50:00. 50 Economy ticket for £27 per person are available. Travel duration is 9h 20m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	8h 35m	22:00	Prague	ÚAN Florenc	06:35	Karlsruhe	Central Station	Economy	£26	A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 10/10/2026 22:00:00 to Central Station, Karlsruhe (Germany) arriving at 11/10/2026 06:35:00. 50 Economy ticket for £26 per person are available. Travel duration is 8h 35m
FlixBus	8h 10m	22:25	Prague	Hradčanská	06:35	Karlsruhe	Central Station	Economy	£26	A Bus from FlixBus goes from Hradčanská, Prague (Czech Republic) at 10/10/2026 22:25:00 to Central Station, Karlsruhe (Germany) arriving at 11/10/2026 06:35:00. 50 Economy ticket for £26 per person are available. Travel duration is 8h 10m
FlixBus	8h 50m	13:05	Prague	Wilsonova Coach Station	21:55	Karlsruhe	Central Station	Economy	£30	A Bus from FlixBus goes from Wilsonova Coach Station, Prague (Czech Republic) at 10/10/2026 13:05:00 to Central Station, Karlsruhe (Germany) arriving at 10/10/2026 21:55:00. 50 Economy ticket for £30 per person are available. Travel duration is 8h 50m
FlixBus	8h 35m	06:40	Prague	ÚAN Florenc	15:15	Karlsruhe	Central Station	Economy	£30	A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 10/10/2026 06:40:00 to Central Station, Karlsruhe (Germany) arriving at 10/10/2026 15:15:00. 50 Economy ticket for £30 per person are available. Travel duration is 8h 35m
FlixBus	9h 5m	12:50	Prague	ÚAN Florenc	21:55	Karlsruhe	Central Station	Economy	£30	A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 10/10/2026 12:50:00 to Central Station, Karlsruhe (Germany) arriving at 10/10/2026 21:55:00. 50 Economy ticket for £30 per person are available. Travel duration is 9h 5m

Best Price Offer: The price for the cheapest coach from Prague to Karlsruhe is £22 on 14/10/2026. Flexible travellers save on ticket prices.

Frequency of bus connections between Prague and Karlsruhe

See here how frequent the connections between Prague and Karlsruhe are, during different times and days of the week.

Thursday is the busiest day, with more than 20 daily coaches from Prague to Karlsruhe. Tuesday has instead the fewest connections, with only 16 daily coaches between Prague and Karlsruhe.

The busiest time of the day is the Afternoon, with 42 coaches from Prague to Karlsruhe, while Night sees the fewest connections between Prague and Karlsruhe, with 14 offers.

Facts about coaches from Prague to Karlsruhe

Compare all providers like FlixBus that travel 18 times every day by bus from Prague to Karlsruhe in one click! Book your bus ticket from Prague to Karlsruhe starting from £22!

Cheapest Bus	£22
Fastest Bus	8h 10m
Earliest Coach	06:40
Latest Coach	23:50
Daily Bus Connections	18 Ø
Distance	451.2 km
Coach Companies	FlixBus

Cheapest coach connections from Prague to Karlsruhe

Every day, 18 buses from 1 coach companies leave Prague for Karlsruhe: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 04/10/2026 and for the following days.

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday

Monday 28/09

Tuesday 29/09

Wednesday 30/09

Thursday 01/10

Friday 02/10

Saturday 03/10

Sunday 04/10

£27

Monday 05/10

£23

Tuesday 06/10

£24

Wednesday 07/10

£24

Thursday 08/10

£22

Friday 09/10

£25

Saturday 10/10

£26

Sunday 11/10

£33

Monday 12/10

Tuesday 13/10

£23

Wednesday 14/10

£22

Thursday 15/10

£23

Friday 16/10

£25

Saturday 17/10

£26

Sunday 18/10

£27

Monday 19/10

£23

Tuesday 20/10

£23

Wednesday 21/10

£23

Thursday 22/10

£23

Friday 23/10

£27

Saturday 24/10

£30

Sunday 25/10

The cheapest time to travel from Prague to Karlsruhe

See here on which day and which time of the day you can find the cheapest bus ticket from Prague to Karlsruhe, for the next 30 days.

With a price starting from £22, Wednesday is the cheapest day for a coach from Prague to Karlsruhe. Sunday instead is the most expensive day with prices starting from £27.

Night is the cheapest day time for bus tickets from Prague to Karlsruhe, with £22. Morning is the most expensive time of the day with prices starting from £22.

How to save money travelling from Prague to Karlsruhe

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Prague to Karlsruhe in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Prague to Karlsruhe, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Prague to Karlsruhe are also emptier.

All bus stations and stops in Prague and Karlsruhe

The map below shows you where to find all the bus stations in Prague and Karlsruhe.

Na Knížecí Station

Za Ženskými domovy / Ostrovského

ÚAN Florenc

Křižíkova 279

Wilsonova Coach Station

Wilsonova 300/8

Roztyly

Tomíčkova 2234

Hradčanská

Milady Horákové 115/107

Central Bus Station

Central Station

Hinterm Hauptbahnhof 6

Durlach Train Station

Knielingen Train Station

Hagsfeld Train Station

Service and Comfort on the bus from Prague to Karlsruhe

Want to know which seat classes are available on the coaches from Prague to Karlsruhe? Or which bus companies serve the route Prague to Karlsruhe? Below you will find answers to your questions.

FAQs about the Prague to Karlsruhe bus

How much does a Prague - Karlsruhe coach trip cost?

This depends on, among other things, the day and travel time. The cheapest ticket for the Prague - Karlsruhe bus trip is available from £22 and takes 8h 35m. Compare offers and save money!

How much could I save by comparing buses from Prague to Karlsruhe?

The connection Prague to Karlsruhe is offered by 1 companies with ticket prices ranging from £22 to £73. Therefore, we suggest booking your ticket as soon as possible to ensure you will get the cheapest ticket price.

How many connections are available for the Prague - Karlsruhe route on average every day?

Each day, the bus route from Prague to Karlsruhe is offered by roughly 18 busses. By using our search, you can compare bus schedules and find your ideal trip.

How long does a bus to Karlsruhe from Prague take?

The quickest coach from Prague to Karlsruhe is provided by FlixBus and takes 8h 10m. Coach tickets for this connection cost £39. However, keep in mind that the connection can take longer due to traffic.

What time is the first bus from Prague to Karlsruhe?

The earliest bus to Karlsruhe departs from Prague at 06:40. In this context, information about departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

What time is the last coach from Prague to Karlsruhe?

The latest bus to Karlsruhe departs from Prague at 23:50. Please note that departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

Which bus companies serve the Prague - Karlsruhe route?

Passengers looking to travel from Prague to Karlsruhe can travel with FlixBus. Compare all available bus tickets with our search to book the trip that works best for you.

Is there a direct bus between Prague and Karlsruhe?

You can check all the direct connections between Prague and Karlsruhe by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus.

What can I take with me on the bus to Karlsruhe from Prague?

Depending on which provider you travel with, what you are allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the bus for the Prague Karlsruhe bus route free of charge. Simply use our search to find a coach that is best suited to your needs for your planned travel date.

What equipment is available for the Prague Karlsruhe bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make travelling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Prague to Karlsruhe on your planned travel date.

How does CheckMyBus find the best bus deals from Prague to Karlsruhe?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 18 daily trips between Prague and Karlsruhe. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Prague to Karlsruhe?

Prices and availability for 18 trips between Prague and Karlsruhe change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Prague to Karlsruhe

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Prague and to Karlsruhe

Here’s an overview of the most popular bus routes to Prague and to Karlsruhe. Simply click on the connection of your choice, and you will find all the details about your bus route!