Bus and Coach from Prague to Frankfurt am Main: Compare all prices

Compare all timetables for the bus from Prague to Frankfurt am Main

Here is a selection of the cheapest bus trips from the schedule from Prague to Frankfurt am Main from various bus operators like FlixBus for the next days.

today

£44

tomorrow

£50

Sunday

£49

Monday

£47

Tuesday

£47

Wednesday

£43

Thursday

£41

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	7h 35m	09:10	Prague	Na Knížecí Station	16:45	Frankfurt am Main	Central Station	Economy	£44	A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 19/12/2025 09:10:00 to Central Station, Frankfurt am Main (Germany) arriving at 19/12/2025 16:45:00. 50 Economy ticket for £44 per person are available. Travel duration is 7h 35m
FlixBus	7h 35m	16:15	Prague	ÚAN Florenc	23:50	Frankfurt am Main	Central Station	Economy	£44	A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 19/12/2025 16:15:00 to Central Station, Frankfurt am Main (Germany) arriving at 19/12/2025 23:50:00. 50 Economy ticket for £44 per person are available. Travel duration is 7h 35m
FlixBus	7h 45m	22:15	Prague	Na Knížecí Station	06:00	Frankfurt am Main	Central Station	Economy	£47	A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 19/12/2025 22:15:00 to Central Station, Frankfurt am Main (Germany) arriving at 20/12/2025 06:00:00. 50 Economy ticket for £47 per person are available. Travel duration is 7h 45m
FlixBus	6h 55m	23:05	Prague	ÚAN Florenc	06:00	Frankfurt am Main	Central Station	Economy	£50	A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 19/12/2025 23:05:00 to Central Station, Frankfurt am Main (Germany) arriving at 20/12/2025 06:00:00. 50 Economy ticket for £50 per person are available. Travel duration is 6h 55m
FlixBus	7h 55m	17:15	Prague	Na Knížecí Station	01:10	Frankfurt am Main	Central Station	Economy	£51	A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 19/12/2025 17:15:00 to Central Station, Frankfurt am Main (Germany) arriving at 20/12/2025 01:10:00. 50 Economy ticket for £51 per person are available. Travel duration is 7h 55m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	7h 20m	20:40	Prague	Na Knížecí Station	04:00	Frankfurt am Main	Central Station	Economy	£50	A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 20/12/2025 20:40:00 to Central Station, Frankfurt am Main (Germany) arriving at 21/12/2025 04:00:00. 50 Economy ticket for £50 per person are available. Travel duration is 7h 20m
FlixBus	8h 30m	19:30	Prague	ÚAN Florenc	04:00	Frankfurt am Main	Central Station	Economy	£50	A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 20/12/2025 19:30:00 to Central Station, Frankfurt am Main (Germany) arriving at 21/12/2025 04:00:00. 50 Economy ticket for £50 per person are available. Travel duration is 8h 30m
FlixBus	7h 30m	03:50	Prague	Wilsonova Coach Station	11:20	Frankfurt am Main	Central Station	Economy	£51	A Bus from FlixBus goes from Wilsonova Coach Station, Prague (Czech Republic) at 20/12/2025 03:50:00 to Central Station, Frankfurt am Main (Germany) arriving at 20/12/2025 11:20:00. 50 Economy ticket for £51 per person are available. Travel duration is 7h 30m
FlixBus	7h 10m	04:10	Prague	Na Knížecí Station	11:20	Frankfurt am Main	Central Station	Economy	£51	A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 20/12/2025 04:10:00 to Central Station, Frankfurt am Main (Germany) arriving at 20/12/2025 11:20:00. 50 Economy ticket for £51 per person are available. Travel duration is 7h 10m
FlixBus	7h 45m	22:15	Prague	Na Knížecí Station	06:00	Frankfurt am Main	Central Station	Economy	£51	A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 20/12/2025 22:15:00 to Central Station, Frankfurt am Main (Germany) arriving at 21/12/2025 06:00:00. 50 Economy ticket for £51 per person are available. Travel duration is 7h 45m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	10h 0m	22:15	Prague	Na Knížecí Station	08:15	Frankfurt am Main	Central Station	Economy	£49	A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 21/12/2025 22:15:00 to Central Station, Frankfurt am Main (Germany) arriving at 22/12/2025 08:15:00. 50 Economy ticket for £49 per person are available. Travel duration is 10h 0m
FlixBus	8h 55m	19:05	Prague	Wilsonova Coach Station	04:00	Frankfurt am Main	Central Station	Economy	£50	A Bus from FlixBus goes from Wilsonova Coach Station, Prague (Czech Republic) at 21/12/2025 19:05:00 to Central Station, Frankfurt am Main (Germany) arriving at 22/12/2025 04:00:00. 50 Economy ticket for £50 per person are available. Travel duration is 8h 55m
FlixBus	7h 25m	17:45	Prague	Na Knížecí Station	01:10	Frankfurt am Main	Central Station	Economy	£50	A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 21/12/2025 17:45:00 to Central Station, Frankfurt am Main (Germany) arriving at 22/12/2025 01:10:00. 50 Economy ticket for £50 per person are available. Travel duration is 7h 25m
FlixBus	7h 20m	20:40	Prague	Na Knížecí Station	04:00	Frankfurt am Main	Central Station	Economy	£50	A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 21/12/2025 20:40:00 to Central Station, Frankfurt am Main (Germany) arriving at 22/12/2025 04:00:00. 50 Economy ticket for £50 per person are available. Travel duration is 7h 20m
FlixBus	8h 10m	21:50	Prague	Na Knížecí Station	06:00	Frankfurt am Main	Central Station	Economy	£50	A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 21/12/2025 21:50:00 to Central Station, Frankfurt am Main (Germany) arriving at 22/12/2025 06:00:00. 50 Economy ticket for £50 per person are available. Travel duration is 8h 10m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	7h 55m	17:15	Prague	Na Knížecí Station	01:10	Frankfurt am Main	Central Station	Economy	£47	A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 22/12/2025 17:15:00 to Central Station, Frankfurt am Main (Germany) arriving at 23/12/2025 01:10:00. 50 Economy ticket for £47 per person are available. Travel duration is 7h 55m
FlixBus	8h 15m	17:45	Prague	Na Knížecí Station	02:00	Frankfurt am Main	Central Station	Economy	£47	A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 22/12/2025 17:45:00 to Central Station, Frankfurt am Main (Germany) arriving at 23/12/2025 02:00:00. 50 Economy ticket for £47 per person are available. Travel duration is 8h 15m
FlixBus	8h 10m	21:50	Prague	Na Knížecí Station	06:00	Frankfurt am Main	Central Station	Economy	£47	A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 22/12/2025 21:50:00 to Central Station, Frankfurt am Main (Germany) arriving at 23/12/2025 06:00:00. 50 Economy ticket for £47 per person are available. Travel duration is 8h 10m
FlixBus	10h 0m	22:15	Prague	Na Knížecí Station	08:15	Frankfurt am Main	Central Station	Economy	£49	A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 22/12/2025 22:15:00 to Central Station, Frankfurt am Main (Germany) arriving at 23/12/2025 08:15:00. 50 Economy ticket for £49 per person are available. Travel duration is 10h 0m
FlixBus	9h 0m	09:55	Prague	Zličín	18:55	Frankfurt am Main	Central Station	Economy	£50	A Bus from FlixBus goes from Zličín, Prague (Czech Republic) at 22/12/2025 09:55:00 to Central Station, Frankfurt am Main (Germany) arriving at 22/12/2025 18:55:00. 50 Economy ticket for £50 per person are available. Travel duration is 9h 0m

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	8h 10m	19:05	Prague	Wilsonova Coach Station	03:15	Frankfurt am Main	Central Station	Economy	£47	A Bus from FlixBus goes from Wilsonova Coach Station, Prague (Czech Republic) at 23/12/2025 19:05:00 to Central Station, Frankfurt am Main (Germany) arriving at 24/12/2025 03:15:00. 50 Economy ticket for £47 per person are available. Travel duration is 8h 10m
FlixBus	9h 30m	17:45	Prague	Na Knížecí Station	03:15	Frankfurt am Main	Central Station	Economy	£47	A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 23/12/2025 17:45:00 to Central Station, Frankfurt am Main (Germany) arriving at 24/12/2025 03:15:00. 50 Economy ticket for £47 per person are available. Travel duration is 9h 30m
FlixBus	7h 45m	19:30	Prague	ÚAN Florenc	03:15	Frankfurt am Main	Central Station	Economy	£47	A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 23/12/2025 19:30:00 to Central Station, Frankfurt am Main (Germany) arriving at 24/12/2025 03:15:00. 50 Economy ticket for £47 per person are available. Travel duration is 7h 45m
FlixBus	10h 0m	22:15	Prague	Na Knížecí Station	08:15	Frankfurt am Main	Central Station	Economy	£48	A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 23/12/2025 22:15:00 to Central Station, Frankfurt am Main (Germany) arriving at 24/12/2025 08:15:00. 50 Economy ticket for £48 per person are available. Travel duration is 10h 0m
FlixBus	8h 10m	21:50	Prague	Na Knížecí Station	06:00	Frankfurt am Main	Central Station	Economy	£50	A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 23/12/2025 21:50:00 to Central Station, Frankfurt am Main (Germany) arriving at 24/12/2025 06:00:00. 50 Economy ticket for £50 per person are available. Travel duration is 8h 10m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	8h 15m	17:45	Prague	Na Knížecí Station	02:00	Frankfurt am Main	Central Station	Economy	£43	A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 24/12/2025 17:45:00 to Central Station, Frankfurt am Main (Germany) arriving at 25/12/2025 02:00:00. 50 Economy ticket for £43 per person are available. Travel duration is 8h 15m
FlixBus	8h 10m	21:50	Prague	Na Knížecí Station	06:00	Frankfurt am Main	Central Station	Economy	£43	A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 24/12/2025 21:50:00 to Central Station, Frankfurt am Main (Germany) arriving at 25/12/2025 06:00:00. 50 Economy ticket for £43 per person are available. Travel duration is 8h 10m
FlixBus	9h 0m	09:55	Prague	Zličín	18:55	Frankfurt am Main	Central Station	Economy	£43	A Bus from FlixBus goes from Zličín, Prague (Czech Republic) at 24/12/2025 09:55:00 to Central Station, Frankfurt am Main (Germany) arriving at 24/12/2025 18:55:00. 50 Economy ticket for £43 per person are available. Travel duration is 9h 0m
FlixBus	8h 55m	19:05	Prague	Wilsonova Coach Station	04:00	Frankfurt am Main	Central Station	Economy	£44	A Bus from FlixBus goes from Wilsonova Coach Station, Prague (Czech Republic) at 24/12/2025 19:05:00 to Central Station, Frankfurt am Main (Germany) arriving at 25/12/2025 04:00:00. 50 Economy ticket for £44 per person are available. Travel duration is 8h 55m
FlixBus	7h 20m	20:40	Prague	Na Knížecí Station	04:00	Frankfurt am Main	Central Station	Economy	£44	A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 24/12/2025 20:40:00 to Central Station, Frankfurt am Main (Germany) arriving at 25/12/2025 04:00:00. 50 Economy ticket for £44 per person are available. Travel duration is 7h 20m

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	8h 0m	10:55	Prague	Na Knížecí Station	18:55	Frankfurt am Main	Central Station	Economy	£41	A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 25/12/2025 10:55:00 to Central Station, Frankfurt am Main (Germany) arriving at 25/12/2025 18:55:00. 50 Economy ticket for £41 per person are available. Travel duration is 8h 0m
FlixBus	8h 25m	10:30	Prague	ÚAN Florenc	18:55	Frankfurt am Main	Central Station	Economy	£41	A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 25/12/2025 10:30:00 to Central Station, Frankfurt am Main (Germany) arriving at 25/12/2025 18:55:00. 50 Economy ticket for £41 per person are available. Travel duration is 8h 25m
FlixBus	7h 35m	16:15	Prague	ÚAN Florenc	23:50	Frankfurt am Main	Central Station	Economy	£41	A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 25/12/2025 16:15:00 to Central Station, Frankfurt am Main (Germany) arriving at 25/12/2025 23:50:00. 50 Economy ticket for £41 per person are available. Travel duration is 7h 35m
FlixBus	7h 35m	09:10	Prague	Na Knížecí Station	16:45	Frankfurt am Main	Central Station	Economy	£43	A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 25/12/2025 09:10:00 to Central Station, Frankfurt am Main (Germany) arriving at 25/12/2025 16:45:00. 50 Economy ticket for £43 per person are available. Travel duration is 7h 35m
FlixBus	7h 55m	08:50	Prague	ÚAN Florenc	16:45	Frankfurt am Main	Central Station	Economy	£43	A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 25/12/2025 08:50:00 to Central Station, Frankfurt am Main (Germany) arriving at 25/12/2025 16:45:00. 50 Economy ticket for £43 per person are available. Travel duration is 7h 55m

Best Price Offer: The price for the cheapest coach from Prague to Frankfurt am Main is £22 on 07/01/2026. Flexible travellers save on ticket prices.

Frequency of bus connections between Prague and Frankfurt am Main

See here how frequent the connections between Prague and Frankfurt am Main are, during different times and days of the week.

Sunday is the busiest day, with more than 20 daily coaches from Prague to Frankfurt am Main. Friday has instead the fewest connections, with only 13 daily coaches between Prague and Frankfurt am Main.

The busiest time of the day is the Evening, with 40 coaches from Prague to Frankfurt am Main, while Night sees the fewest connections between Prague and Frankfurt am Main, with 12 offers.

Facts about coaches from Prague to Frankfurt am Main

Compare all providers like FlixBus that travel 17 times every day by bus from Prague to Frankfurt am Main in one click! Book your bus ticket from Prague to Frankfurt am Main starting from £22!

Cheapest Bus	£22
Fastest Bus	6h 55m
Earliest Coach	09:10
Latest Coach	23:05
Daily Bus Connections	17 Ø
Distance	410.5 km
Coach Companies	FlixBus

Cheapest coach connections from Prague to Frankfurt am Main

Every day, 17 buses from 1 coach companies leave Prague for Frankfurt am Main: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 19/12/2025 and for the following days.

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday

Monday 15/12

Tuesday 16/12

Wednesday 17/12

Thursday 18/12

Friday 19/12

£41

Saturday 20/12

£50

Sunday 21/12

£49

Monday 22/12

£47

Tuesday 23/12

£47

Wednesday 24/12

£43

Thursday 25/12

£41

Friday 26/12

£42

Saturday 27/12

£45

Sunday 28/12

£48

Monday 29/12

£43

Tuesday 30/12

£38

Wednesday 31/12

£43

Thursday 01/01

£44

Friday 02/01

£39

Saturday 03/01

£41

Sunday 04/01

£41

Monday 05/01

£30

Tuesday 06/01

£26

Wednesday 07/01

£22

Thursday 08/01

£23

Friday 09/01

£26

Saturday 10/01

£25

Sunday 11/01

The cheapest time to travel from Prague to Frankfurt am Main

See here on which day and which time of the day you can find the cheapest bus ticket from Prague to Frankfurt am Main, for the next 30 days.

With a price starting from £19, Wednesday is the cheapest day for a coach from Prague to Frankfurt am Main. Sunday instead is the most expensive day with prices starting from £27.

Night is the cheapest day time for bus tickets from Prague to Frankfurt am Main, with £19. Evening is the most expensive time of the day with prices starting from £43.

How to save money travelling from Prague to Frankfurt am Main

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Prague to Frankfurt am Main in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Prague to Frankfurt am Main, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Prague to Frankfurt am Main are also emptier.

Beloved bus companies from Prague to Frankfurt am Main

These are the most booked bus companies between Prague to Frankfurt am Main from our users.

FlixBus from Prague to Frankfurt am Main

Here you will find the key facts about the FlixBus bus route Prague to Frankfurt am Main:

Cheapest Price	£41
Fastest Coach	6h 55m
Earliest Coach	09:10
Last Coach	23:05
Daily Connections	17 Ø
Found on	19/12/2025

All bus stations and stops in Prague and Frankfurt am Main

The map below shows you where to find all the bus stations in Prague and Frankfurt am Main.

Na Knížecí Station

Za Ženskými domovy / Ostrovského

ÚAN Florenc

Křižíkova 279

Wilsonova Coach Station

Wilsonova 300/8

Roztyly

Tomíčkova 2234

Hradčanská

Milady Horákové 115/107

Central Coach Station

Karlsruher Straße 10

Stuttgarter Strasse Bus Stop

Stuttgarter Str.

Seilerstraße Bus Stop

Baseler Platz Bus Stop

Stresemannallee/Mörfelder Landstr. Bus Stop

Service and Comfort on the bus from Prague to Frankfurt am Main

Want to know which seat classes are available on the coaches from Prague to Frankfurt am Main? Or which bus companies serve the route Prague to Frankfurt am Main? Below you will find answers to your questions.

FAQs about the Prague to Frankfurt am Main bus

How much does a Prague - Frankfurt am Main coach trip cost?

This depends on, among other things, the day and travel time. The cheapest ticket for the Prague - Frankfurt am Main bus trip is available from £22 and takes 8h 0m. Compare offers and save money!

How much could I save by comparing buses from Prague to Frankfurt am Main?

The connection Prague to Frankfurt am Main is offered by 1 companies with ticket prices ranging from £22 to £79. Therefore, we suggest booking your ticket as soon as possible to ensure you will get the cheapest ticket price.

How many connections are available for the Prague - Frankfurt am Main route on average every day?

Each day, the bus route from Prague to Frankfurt am Main is offered by roughly 17 busses. By using our search, you can compare bus schedules and find your ideal trip.

How long does a bus to Frankfurt am Main from Prague take?

The quickest coach from Prague to Frankfurt am Main is provided by FlixBus and takes 6h 55m. Coach tickets for this connection cost £50. However, keep in mind that the connection can take longer due to traffic.

What time is the first bus from Prague to Frankfurt am Main?

The earliest bus to Frankfurt am Main departs from Prague at 09:10. In this context, information about departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

What time is the last coach from Prague to Frankfurt am Main?

The latest bus to Frankfurt am Main departs from Prague at 23:05. Please note that departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

Which bus companies serve the Prague - Frankfurt am Main route?

Passengers looking to travel from Prague to Frankfurt am Main can travel with FlixBus. Compare all available bus tickets with our search to book the trip that works best for you.

Is there a direct bus between Prague and Frankfurt am Main?

You can check all the direct connections between Prague and Frankfurt am Main by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus.

What can I take with me on the bus to Frankfurt am Main from Prague?

Depending on which provider you travel with, what you are allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the bus for the Prague Frankfurt am Main bus route free of charge. Simply use our search to find a coach that is best suited to your needs for your planned travel date.

What equipment is available for the Prague Frankfurt am Main bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make travelling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Prague to Frankfurt am Main on your planned travel date.

How does CheckMyBus find the best bus deals from Prague to Frankfurt am Main?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 17 daily trips between Prague and Frankfurt am Main. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Prague to Frankfurt am Main?

Prices and availability for 17 trips between Prague and Frankfurt am Main change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Prague to Frankfurt am Main

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Prague and to Frankfurt am Main

Here’s an overview of the most popular bus routes to Prague and to Frankfurt am Main. Simply click on the connection of your choice, and you will find all the details about your bus route!