Coach Mexico City to Santiago Tuxtla from £53

Which bus from Mexico City to Santiago Tuxtla is the best?

Check the bus schedule for Mexico City to Santiago Tuxtla. Here is a selection of the cheapest coach trips for the next days from bus operators like ADO. To see the full timetable for all coaches just use or search and compare.

today

£53

tomorrow

£53

Monday

£53

Tuesday

Wednesday

Thursday

Friday

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
ADO	8h 25m	00:04	Mexico City	Terminal de Autobuses de Oriente (TAPO)	08:29	Santiago Tuxtla	Central Bus Station	Economy	£53	A Bus from ADO goes from Terminal de Autobuses de Oriente (TAPO), Mexico City (Mexico) at 02/05/2026 00:04:00 to Central Bus Station, Santiago Tuxtla (Mexico) arriving at 02/05/2026 08:29:00. 50 Economy ticket for £53 per person are available. Travel duration is 8h 25m
ADO	8h 15m	21:05	Mexico City	Terminal de Autobuses de Oriente (TAPO)	05:20	Santiago Tuxtla	Central Bus Station	Economy	£53	A Bus from ADO goes from Terminal de Autobuses de Oriente (TAPO), Mexico City (Mexico) at 02/05/2026 21:05:00 to Central Bus Station, Santiago Tuxtla (Mexico) arriving at 03/05/2026 05:20:00. 50 Economy ticket for £53 per person are available. Travel duration is 8h 15m
ADO	9h 20m	20:00	Mexico City	Norte Bus Station	05:20	Santiago Tuxtla	Central Bus Station	Economy	£53	A Bus from ADO goes from Norte Bus Station, Mexico City (Mexico) at 02/05/2026 20:00:00 to Central Bus Station, Santiago Tuxtla (Mexico) arriving at 03/05/2026 05:20:00. 50 Economy ticket for £53 per person are available. Travel duration is 9h 20m
ADO	9h 19m	23:10	Mexico City	Norte Bus Station	08:29	Santiago Tuxtla	Central Bus Station	Economy	£53	A Bus from ADO goes from Norte Bus Station, Mexico City (Mexico) at 02/05/2026 23:10:00 to Central Bus Station, Santiago Tuxtla (Mexico) arriving at 03/05/2026 08:29:00. 50 Economy ticket for £53 per person are available. Travel duration is 9h 19m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
ADO	8h 25m	00:04	Mexico City	Terminal de Autobuses de Oriente (TAPO)	08:29	Santiago Tuxtla	Central Bus Station	Economy	£53	A Bus from ADO goes from Terminal de Autobuses de Oriente (TAPO), Mexico City (Mexico) at 03/05/2026 00:04:00 to Central Bus Station, Santiago Tuxtla (Mexico) arriving at 03/05/2026 08:29:00. 50 Economy ticket for £53 per person are available. Travel duration is 8h 25m
ADO	7h 55m	21:05	Mexico City	Terminal de Autobuses de Oriente (TAPO)	05:00	Santiago Tuxtla	Central Bus Station	Economy	£53	A Bus from ADO goes from Terminal de Autobuses de Oriente (TAPO), Mexico City (Mexico) at 03/05/2026 21:05:00 to Central Bus Station, Santiago Tuxtla (Mexico) arriving at 04/05/2026 05:00:00. 50 Economy ticket for £53 per person are available. Travel duration is 7h 55m
ADO	8h 55m	22:15	Mexico City	Terminal de Autobuses de Oriente (TAPO)	07:10	Santiago Tuxtla	Central Bus Station	Economy	£53	A Bus from ADO goes from Terminal de Autobuses de Oriente (TAPO), Mexico City (Mexico) at 03/05/2026 22:15:00 to Central Bus Station, Santiago Tuxtla (Mexico) arriving at 04/05/2026 07:10:00. 50 Economy ticket for £53 per person are available. Travel duration is 8h 55m
ADO	9h 0m	20:00	Mexico City	Norte Bus Station	05:00	Santiago Tuxtla	Central Bus Station	Economy	£53	A Bus from ADO goes from Norte Bus Station, Mexico City (Mexico) at 03/05/2026 20:00:00 to Central Bus Station, Santiago Tuxtla (Mexico) arriving at 04/05/2026 05:00:00. 50 Economy ticket for £53 per person are available. Travel duration is 9h 0m
ADO	9h 19m	23:10	Mexico City	Norte Bus Station	08:29	Santiago Tuxtla	Central Bus Station	Economy	£53	A Bus from ADO goes from Norte Bus Station, Mexico City (Mexico) at 03/05/2026 23:10:00 to Central Bus Station, Santiago Tuxtla (Mexico) arriving at 04/05/2026 08:29:00. 50 Economy ticket for £53 per person are available. Travel duration is 9h 19m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
ADO	8h 25m	00:04	Mexico City	Terminal de Autobuses de Oriente (TAPO)	08:29	Santiago Tuxtla	Central Bus Station	Economy	£53	A Bus from ADO goes from Terminal de Autobuses de Oriente (TAPO), Mexico City (Mexico) at 04/05/2026 00:04:00 to Central Bus Station, Santiago Tuxtla (Mexico) arriving at 04/05/2026 08:29:00. 50 Economy ticket for £53 per person are available. Travel duration is 8h 25m
ADO	8h 15m	21:05	Mexico City	Terminal de Autobuses de Oriente (TAPO)	05:20	Santiago Tuxtla	Central Bus Station	Economy	£53	A Bus from ADO goes from Terminal de Autobuses de Oriente (TAPO), Mexico City (Mexico) at 04/05/2026 21:05:00 to Central Bus Station, Santiago Tuxtla (Mexico) arriving at 05/05/2026 05:20:00. 50 Economy ticket for £53 per person are available. Travel duration is 8h 15m
ADO	8h 55m	22:15	Mexico City	Terminal de Autobuses de Oriente (TAPO)	07:10	Santiago Tuxtla	Central Bus Station	Economy	£53	A Bus from ADO goes from Terminal de Autobuses de Oriente (TAPO), Mexico City (Mexico) at 04/05/2026 22:15:00 to Central Bus Station, Santiago Tuxtla (Mexico) arriving at 05/05/2026 07:10:00. 50 Economy ticket for £53 per person are available. Travel duration is 8h 55m
ADO	9h 20m	20:00	Mexico City	Norte Bus Station	05:20	Santiago Tuxtla	Central Bus Station	Economy	£53	A Bus from ADO goes from Norte Bus Station, Mexico City (Mexico) at 04/05/2026 20:00:00 to Central Bus Station, Santiago Tuxtla (Mexico) arriving at 05/05/2026 05:20:00. 50 Economy ticket for £53 per person are available. Travel duration is 9h 20m
ADO	9h 19m	23:10	Mexico City	Norte Bus Station	08:29	Santiago Tuxtla	Central Bus Station	Economy	£53	A Bus from ADO goes from Norte Bus Station, Mexico City (Mexico) at 04/05/2026 23:10:00 to Central Bus Station, Santiago Tuxtla (Mexico) arriving at 05/05/2026 08:29:00. 50 Economy ticket for £53 per person are available. Travel duration is 9h 19m

Did you know that if you travel from Mexico City to Santiago Tuxtla via Veracruz, you can save more than £5? You can find the corresponding connections below.
- Autobuses Unidos
  
  12h 0m
  
  0
  
  08:00
  
  Mexico City
  Santa Martha Acatitla
  
  14:40
  
  Veracruz
  Central bus station
  
  0
  
  Economy
  
  £34
  
  A Bus from Autobuses Unidos goes from Santa Martha Acatitla, Mexico City (Mexico) at 05/05/2026 08:00:00 to Central bus station, Veracruz (Mexico) arriving at 05/05/2026 14:40:00. 50 Economy ticket for £34 per person are available. Travel duration is 6h 40m
- ADO
  
  3h 5m
  
  0
  
  16:55
  
  Veracruz
  Central bus station
  
  20:00
  
  Santiago Tuxtla
  Central Bus Station
  
  0
  
  Economy
  
  £14
  
  A Bus from ADO goes from Central bus station, Veracruz (Mexico) at 05/05/2026 16:55:00 to Central Bus Station, Santiago Tuxtla (Mexico) arriving at 05/05/2026 20:00:00. 50 Economy ticket for £14 per person are available. Travel duration is 3h 5m
Travel time is 3h 45m longer, but you will save £5

Best Price Offer: The price for the cheapest coach from Mexico City to Santiago Tuxtla is £53 on 28/04/2026. Flexible travellers save on ticket prices.

What is the best day and time to travel by bus between Mexico City and Santiago Tuxtla?

Here is the frequency of all coach connections from Mexico City to Santiago Tuxtla. See on which day of the week you have more travel options and what time you have more bus trips to choose from.

Monday is the busiest day, with more than 10 daily coaches from Mexico City to Santiago Tuxtla. Sunday has instead the fewest connections, with only 7 daily coaches between Mexico City and Santiago Tuxtla.

The busiest time of the day is the Evening, with 20 coaches from Mexico City to Santiago Tuxtla, while Night sees the fewest connections between Mexico City and Santiago Tuxtla, with 5 offers.

All facts for Mexico City to Santiago Tuxtla bus at a glance

Compare all coach operators like ADO that travel daily 8 times by bus from Mexico City to Santiago Tuxtla in one click. Book your Mexico City to Santiago Tuxtla bus ticket starting from £53!

Cheapest Bus	£53
Fastest Bus	7h 55m
Earliest Coach	00:04
Latest Coach	23:10
Daily Bus Connections	8 Ø
Distance	417.0 km
Coach Companies	ADO

What are the cheapest coach tickets from Mexico City to Santiago Tuxtla?

Every day, 8 buses from 1 coach companies leave Mexico City for Santiago Tuxtla. Check the table below to find the cheapest prices for coach tickets for this route, starting from 02/05/2026 and for the following days. Make sure get the cheapest bus ticket!

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday

Monday 27/04

Tuesday 28/04

Wednesday 29/04

Thursday 30/04

Friday 01/05

Saturday 02/05

£53

Sunday 03/05

£53

Monday 04/05

£53

Tuesday 05/05

Wednesday 06/05

Thursday 07/05

Friday 08/05

Saturday 09/05

Sunday 10/05

£53

Monday 11/05

£55

Tuesday 12/05

£53

Wednesday 13/05

Thursday 14/05

£54

Friday 15/05

£55

Saturday 16/05

£53

Sunday 17/05

£55

Monday 18/05

£53

Tuesday 19/05

£53

Wednesday 20/05

£53

Thursday 21/05

£53

Friday 22/05

Saturday 23/05

£54

Sunday 24/05

The cheapest time to travel from Mexico City to Santiago Tuxtla

See here on which day and which time of the day you can find the cheapest bus ticket from Mexico City to Santiago Tuxtla, for the next 30 days.

With a price starting from £53, Monday is the cheapest day for a coach from Mexico City to Santiago Tuxtla. Monday instead is the most expensive day with prices starting from £53.

Evening is the cheapest day time for bus tickets from Mexico City to Santiago Tuxtla, with £53. Evening is the most expensive time of the day with prices starting from £53.

How to save money travelling from Mexico City to Santiago Tuxtla

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying higher prices for your trip? Plan your bus trips smartly. Here are a few hacks to save money on your coach journey.

Book the ticket from Mexico City to Santiago Tuxtla in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the coach from Mexico City to Santiago Tuxtla, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Mexico City to Santiago Tuxtla are also emptier.

Check for bus deals and promotions for all bus companies in this route. On CheckMyBus we show special offers directly in the coach trip on our search. Sign-up and check or deals sections and get notifications on our latest travel hacks.

All bus stations and stops in Mexico City and Santiago Tuxtla

Here is a map with all coach stations in Mexico City and Santiago Tuxtla. Compare which stop is closest to your destination to save time to find the fastest buses and connections.

Norte Bus Station

Eje Central Lázaro Cárdenas

Terminal de Autobuses de Oriente (TAPO)

Calz. Ignacio Zaragoza 200

Moctezuma Coach Stop

Ampliación 7 de Julio

Terminal Antas Tla

Emiliano Zapata 97

Fórum Buenavista

Mexico City Buenavista (Fórum Buenavista) Mexico City Buenavista (Fórum Buenavista)

Central Bus Station

Morelos 190

All you need to know when you travel by bus from Mexico City to Santiago Tuxtla

Check all information on comfort and services on the coaches from Mexico City to Santiago Tuxtla. Which seat classes are available or what are the amenities of operators on your coach trip? Below you´ll find answers to your questions.

FAQs for Mexico City to Santiago Tuxtla bus

How much does a Mexico City Santiago Tuxtla coach trip cost?

This depends on, among other things, the day and travel time. The cheapest ticket for the Mexico City Santiago Tuxtla bus trip is available from £53 and takes 8h 25m. Compare offers and save money!

How much could I save by comparing buses from Mexico City to Santiago Tuxtla?

This connection is offered by 1 companies with ticket prices ranging from £53 to £54. Therefore, we suggest booking your ticket as soon as possible to ensure you’ll get the cheapest bus trip to Santiago Tuxtla.

How many connections are available for the Mexico City Santiago Tuxtla route on average every day?

Each day, the bus route from Mexico City to Santiago Tuxtla is offered by roughly 8 busses. By using our search, you can compare bus schedules and find your ideal trip.

How long does a bus to Santiago Tuxtla from Mexico City take?

The quickest coach from Mexico City to Santiago Tuxtla is provided by ADO and takes 7h 55m. Coach tickets for this connection cost £53. However, keep in mind that the connection can take longer due to traffic.

What time is the first bus from Mexico City to Santiago Tuxtla?

The earliest bus to Santiago Tuxtla departs from Mexico City at 00:04. In this context, information about departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

What time is the last coach from Mexico City to Santiago Tuxtla?

The latest bus to Santiago Tuxtla departs from Mexico City at 23:10. Please note that departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

Which bus companies serve the Mexico City Santiago Tuxtla route?

Passengers looking to travel from Mexico City to Santiago Tuxtla can travel with ADO. Compare all available bus tickets with our search to book the trip that works best for you.

Is there a direct bus between Mexico City and Santiago Tuxtla?

You can check all the direct connections between Mexico City and Santiago Tuxtla by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: ADO.

What can I take with me on the bus to Santiago Tuxtla from Mexico City?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the bus for the Mexico City Santiago Tuxtla bus route free of charge. Simply use our search to find a coach that is best suited to your needs for your planned travel date.

What equipment is available for the Mexico City Santiago Tuxtla bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make travelling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Mexico City to Santiago Tuxtla on your planned travel date.

How does CheckMyBus find the best coach deals from Mexico City to Santiago Tuxtla?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 8 daily trips between Mexico City and Santiago Tuxtla. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Mexico City to Santiago Tuxtla?

Prices and availability for 8 trips between Mexico City and Santiago Tuxtla change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Mexico City to Santiago Tuxtla

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Mexico City and to Santiago Tuxtla

Here’s an overview of the most popular bus routes to Mexico City and to Santiago Tuxtla. Simply click on the connection of your choice, and you’ll find all the details about your bus route!