Which bus from Mexico City to Santiago Tuxtla is the best?
Check the bus schedule for Mexico City to Santiago Tuxtla. Here is a selection of the cheapest coach trips for the next days from bus operators like ADO. To see the full timetable for all coaches just use or search and compare.
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ADO | 8h 55m | 20:00 | Mexico City | Norte Bus Station | 04:55 | Santiago Tuxtla | Central Bus Station | Economy | £52 |
A Bus from ADO goes from Norte Bus Station, Mexico City (Mexico) at 01/02/2026 20:00:00 to Central Bus Station, Santiago Tuxtla (Mexico) arriving at 02/02/2026 04:55:00. 50 Economy ticket for £52 per person are available. Travel duration is 8h 55m
|
||
| ADO | 9h 14m | 23:10 | Mexico City | Norte Bus Station | 08:24 | Santiago Tuxtla | Central Bus Station | Economy | £52 |
A Bus from ADO goes from Norte Bus Station, Mexico City (Mexico) at 01/02/2026 23:10:00 to Central Bus Station, Santiago Tuxtla (Mexico) arriving at 02/02/2026 08:24:00. 50 Economy ticket for £52 per person are available. Travel duration is 9h 14m
|
||
| ADO | 7h 55m | 21:00 | Mexico City | Terminal de Autobuses de Oriente (TAPO) | 04:55 | Santiago Tuxtla | Central Bus Station | Economy | £52 |
A Bus from ADO goes from Terminal de Autobuses de Oriente (TAPO), Mexico City (Mexico) at 01/02/2026 21:00:00 to Central Bus Station, Santiago Tuxtla (Mexico) arriving at 02/02/2026 04:55:00. 50 Economy ticket for £52 per person are available. Travel duration is 7h 55m
|
||
| ADO | 9h 0m | 22:15 | Mexico City | Terminal de Autobuses de Oriente (TAPO) | 07:15 | Santiago Tuxtla | Central Bus Station | Economy | £52 |
A Bus from ADO goes from Terminal de Autobuses de Oriente (TAPO), Mexico City (Mexico) at 01/02/2026 22:15:00 to Central Bus Station, Santiago Tuxtla (Mexico) arriving at 02/02/2026 07:15:00. 50 Economy ticket for £52 per person are available. Travel duration is 9h 0m
|
||
| ADO | 8h 25m | 23:59 | Mexico City | Terminal de Autobuses de Oriente (TAPO) | 08:24 | Santiago Tuxtla | Central Bus Station | Economy | £52 |
A Bus from ADO goes from Terminal de Autobuses de Oriente (TAPO), Mexico City (Mexico) at 01/02/2026 23:59:00 to Central Bus Station, Santiago Tuxtla (Mexico) arriving at 02/02/2026 08:24:00. 50 Economy ticket for £52 per person are available. Travel duration is 8h 25m
|
-
-
ClickBus MX11h 35m007:15Mexico CityNorte Bus Station14:57VeracruzBus Stop0EconomyA Bus from ClickBus MX goes from Norte Bus Station, Mexico City (Mexico) at 02/02/2026 07:15:00 to Bus Stop, Veracruz (Mexico) arriving at 02/02/2026 14:57:00. 50 Economy ticket for £24 per person are available. Travel duration is 7h 42m
-
ClickBus MX3h 5m015:45VeracruzCentral bus station18:50Santiago TuxtlaCentral Bus Station0EconomyA Bus from ClickBus MX goes from Central bus station, Veracruz (Mexico) at 02/02/2026 15:45:00 to Central Bus Station, Santiago Tuxtla (Mexico) arriving at 02/02/2026 18:50:00. 50 Economy ticket for £14 per person are available. Travel duration is 3h 5m
Waiting Time 0h 48m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ADO | 9h 15m | 20:00 | Mexico City | Norte Bus Station | 05:15 | Santiago Tuxtla | Central Bus Station | Economy | £52 |
A Bus from ADO goes from Norte Bus Station, Mexico City (Mexico) at 06/02/2026 20:00:00 to Central Bus Station, Santiago Tuxtla (Mexico) arriving at 07/02/2026 05:15:00. 50 Economy ticket for £52 per person are available. Travel duration is 9h 15m
|
||
| ADO | 9h 14m | 23:10 | Mexico City | Norte Bus Station | 08:24 | Santiago Tuxtla | Central Bus Station | Economy | £52 |
A Bus from ADO goes from Norte Bus Station, Mexico City (Mexico) at 06/02/2026 23:10:00 to Central Bus Station, Santiago Tuxtla (Mexico) arriving at 07/02/2026 08:24:00. 50 Economy ticket for £52 per person are available. Travel duration is 9h 14m
|
||
| ADO | 8h 15m | 21:00 | Mexico City | Terminal de Autobuses de Oriente (TAPO) | 05:15 | Santiago Tuxtla | Central Bus Station | Economy | £52 |
A Bus from ADO goes from Terminal de Autobuses de Oriente (TAPO), Mexico City (Mexico) at 06/02/2026 21:00:00 to Central Bus Station, Santiago Tuxtla (Mexico) arriving at 07/02/2026 05:15:00. 50 Economy ticket for £52 per person are available. Travel duration is 8h 15m
|
||
| ADO | 9h 0m | 22:15 | Mexico City | Terminal de Autobuses de Oriente (TAPO) | 07:15 | Santiago Tuxtla | Central Bus Station | Economy | £52 |
A Bus from ADO goes from Terminal de Autobuses de Oriente (TAPO), Mexico City (Mexico) at 06/02/2026 22:15:00 to Central Bus Station, Santiago Tuxtla (Mexico) arriving at 07/02/2026 07:15:00. 50 Economy ticket for £52 per person are available. Travel duration is 9h 0m
|
||
| ADO | 9h 0m | 23:30 | Mexico City | Terminal de Autobuses de Oriente (TAPO) | 08:30 | Santiago Tuxtla | Central Bus Station | Economy | £52 |
A Bus from ADO goes from Terminal de Autobuses de Oriente (TAPO), Mexico City (Mexico) at 06/02/2026 23:30:00 to Central Bus Station, Santiago Tuxtla (Mexico) arriving at 07/02/2026 08:30:00. 50 Economy ticket for £52 per person are available. Travel duration is 9h 0m
|
-
-
ClickBus MX11h 35m007:15Mexico CityNorte Bus Station14:57VeracruzBus Stop0EconomyA Bus from ClickBus MX goes from Norte Bus Station, Mexico City (Mexico) at 02/02/2026 07:15:00 to Bus Stop, Veracruz (Mexico) arriving at 02/02/2026 14:57:00. 50 Economy ticket for £24 per person are available. Travel duration is 7h 42m
-
ClickBus MX3h 5m015:45VeracruzCentral bus station18:50Santiago TuxtlaCentral Bus Station0EconomyA Bus from ClickBus MX goes from Central bus station, Veracruz (Mexico) at 02/02/2026 15:45:00 to Central Bus Station, Santiago Tuxtla (Mexico) arriving at 02/02/2026 18:50:00. 50 Economy ticket for £14 per person are available. Travel duration is 3h 5m
Waiting Time 0h 48m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ADO | 9h 15m | 20:00 | Mexico City | Norte Bus Station | 05:15 | Santiago Tuxtla | Central Bus Station | Economy | £53 |
A Bus from ADO goes from Norte Bus Station, Mexico City (Mexico) at 07/02/2026 20:00:00 to Central Bus Station, Santiago Tuxtla (Mexico) arriving at 08/02/2026 05:15:00. 50 Economy ticket for £53 per person are available. Travel duration is 9h 15m
|
||
| ADO | 9h 14m | 23:10 | Mexico City | Norte Bus Station | 08:24 | Santiago Tuxtla | Central Bus Station | Economy | £53 |
A Bus from ADO goes from Norte Bus Station, Mexico City (Mexico) at 07/02/2026 23:10:00 to Central Bus Station, Santiago Tuxtla (Mexico) arriving at 08/02/2026 08:24:00. 50 Economy ticket for £53 per person are available. Travel duration is 9h 14m
|
||
| ADO | 8h 15m | 21:00 | Mexico City | Terminal de Autobuses de Oriente (TAPO) | 05:15 | Santiago Tuxtla | Central Bus Station | Economy | £53 |
A Bus from ADO goes from Terminal de Autobuses de Oriente (TAPO), Mexico City (Mexico) at 07/02/2026 21:00:00 to Central Bus Station, Santiago Tuxtla (Mexico) arriving at 08/02/2026 05:15:00. 50 Economy ticket for £53 per person are available. Travel duration is 8h 15m
|
||
| ADO | 9h 0m | 22:15 | Mexico City | Terminal de Autobuses de Oriente (TAPO) | 07:15 | Santiago Tuxtla | Central Bus Station | Economy | £53 |
A Bus from ADO goes from Terminal de Autobuses de Oriente (TAPO), Mexico City (Mexico) at 07/02/2026 22:15:00 to Central Bus Station, Santiago Tuxtla (Mexico) arriving at 08/02/2026 07:15:00. 50 Economy ticket for £53 per person are available. Travel duration is 9h 0m
|
||
| ADO | 8h 25m | 23:59 | Mexico City | Terminal de Autobuses de Oriente (TAPO) | 08:24 | Santiago Tuxtla | Central Bus Station | Economy | £53 |
A Bus from ADO goes from Terminal de Autobuses de Oriente (TAPO), Mexico City (Mexico) at 07/02/2026 23:59:00 to Central Bus Station, Santiago Tuxtla (Mexico) arriving at 08/02/2026 08:24:00. 50 Economy ticket for £53 per person are available. Travel duration is 8h 25m
|
-
-
ClickBus MX11h 35m007:15Mexico CityNorte Bus Station14:57VeracruzBus Stop0EconomyA Bus from ClickBus MX goes from Norte Bus Station, Mexico City (Mexico) at 02/02/2026 07:15:00 to Bus Stop, Veracruz (Mexico) arriving at 02/02/2026 14:57:00. 50 Economy ticket for £24 per person are available. Travel duration is 7h 42m
-
ClickBus MX3h 5m015:45VeracruzCentral bus station18:50Santiago TuxtlaCentral Bus Station0EconomyA Bus from ClickBus MX goes from Central bus station, Veracruz (Mexico) at 02/02/2026 15:45:00 to Central Bus Station, Santiago Tuxtla (Mexico) arriving at 02/02/2026 18:50:00. 50 Economy ticket for £14 per person are available. Travel duration is 3h 5m
Waiting Time 0h 48m -
Best Price Offer: The price for the cheapest coach from Mexico City to Santiago Tuxtla is £52 on 06/02/2026. Flexible travellers save on ticket prices.
All facts for Mexico City to Santiago Tuxtla bus at a glance
Compare all coach operators like ADO that travel daily 7 times by bus from Mexico City to Santiago Tuxtla in one click. Book your Mexico City to Santiago Tuxtla bus ticket starting from £52!
| Cheapest Bus | £52 |
| Fastest Bus | 7h 55m |
| Earliest Coach | 20:00 |
| Latest Coach | 23:59 |
| Daily Bus Connections | 7 Ø |
| Distance | 417.0 km |
| Coach Companies | ADO |
What are the cheapest coach tickets from Mexico City to Santiago Tuxtla?
Every day, 7 buses from 1 coach companies leave Mexico City for Santiago Tuxtla. Check the table below to find the cheapest prices for coach tickets for this route, starting from 01/02/2026 and for the following days. Make sure get the cheapest bus ticket!
How to save money travelling from Mexico City to Santiago Tuxtla
Book the ticket from Mexico City to Santiago Tuxtla in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the coach from Mexico City to Santiago Tuxtla, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Mexico City to Santiago Tuxtla are also emptier.Check for bus deals and promotions for all bus companies in this route. On CheckMyBus we show special offers directly in the coach trip on our search. Sign-up and check or deals sections and get notifications on our latest travel hacks.
All bus stations and stops in Mexico City and Santiago Tuxtla
Here is a map with all coach stations in Mexico City and Santiago Tuxtla. Compare which stop is closest to your destination to save time to find the fastest buses and connections.
All you need to know when you travel by bus from Mexico City to Santiago Tuxtla
FAQs for Mexico City to Santiago Tuxtla bus
How much does a Mexico City Santiago Tuxtla coach trip cost?
How much could I save by comparing buses from Mexico City to Santiago Tuxtla?
How many connections are available for the Mexico City Santiago Tuxtla route on average every day?
How long does a bus to Santiago Tuxtla from Mexico City take?
What time is the first bus from Mexico City to Santiago Tuxtla?
What time is the last coach from Mexico City to Santiago Tuxtla?
Which bus companies serve the Mexico City Santiago Tuxtla route?
Is there a direct bus between Mexico City and Santiago Tuxtla?
What can I take with me on the bus to Santiago Tuxtla from Mexico City?
What equipment is available for the Mexico City Santiago Tuxtla bus route?
How does CheckMyBus find the best coach deals from Mexico City to Santiago Tuxtla?
How does CheckMyBus technology work for trips from Mexico City to Santiago Tuxtla?
Available seat classes which are offered on the bus route Mexico City to Santiago Tuxtla
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
More bus routes to Mexico City and to Santiago Tuxtla
- Bus Routes to Mexico City
- Buses Cerro Azul to Mexico City
- Bus from Chalma to Mexico City
- Coach from Ciudad Guzmán to Mexico City
- Buses Ciudad Victoria to Mexico City
- Coach from Cuautla to Mexico City
- Coach from El Tephe to Mexico City
- Huejutla to Mexico City coach
- Coach Juchitán de Zaragoza to Mexico City
- Coach Lázaro Cárdenas, MN to Mexico City
- Coaches Manzanillo, CL to Mexico City
- Bus from Mexicali to Mexico City
- Pátzcuaro to Mexico City coach
- Bus Pijijiapan to Mexico City
- Bus Poza Rica to Mexico City
- Coach Saltillo to Mexico City
- Bus to Mexico City from San Luis Potosí
- Bus Tlaxcala City, TL to Mexico City
- Coach from Torreón, CO to Mexico City
- Coach to Mexico City from Uruapan, MN
- Zapopan to Mexico City bus
