Which bus from Frankfurt am Main to Prague is the best?
Check the bus schedule for Frankfurt am Main to Prague. Here is a selection of the cheapest coach trips for the next days from bus operators like FlixBus or KLR Bus. To see the full timetable for all coaches just use or search and compare.
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 9h 55m | 06:05 | Frankfurt am Main | Central Station | 16:00 | Prague | Wilsonova Coach Station | Economy | £21 |
A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 16/09/2026 06:05:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 16/09/2026 16:00:00. 50 Economy ticket for £21 per person are available. Travel duration is 9h 55m
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| FlixBus | 7h 25m | 06:05 | Frankfurt am Main | Central Station | 13:30 | Prague | ÚAN Florenc | Economy | £25 |
A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 16/09/2026 06:05:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 16/09/2026 13:30:00. 50 Economy ticket for £25 per person are available. Travel duration is 7h 25m
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| FlixBus | 7h 0m | 14:30 | Frankfurt am Main | Central Station | 21:30 | Prague | ÚAN Florenc | Economy | £25 |
A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 16/09/2026 14:30:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 16/09/2026 21:30:00. 50 Economy ticket for £25 per person are available. Travel duration is 7h 0m
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| KLR Bus | 13h 20m | 18:30 | Frankfurt am Main | Central Station | 07:50 | Prague | ÚAN Florenc | Economy | £29 |
A Bus from KLR Bus goes from Central Station, Frankfurt am Main (Germany) at 16/09/2026 18:30:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 17/09/2026 07:50:00. 50 Economy ticket for £29 per person are available. Travel duration is 13h 20m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 9h 50m | 01:40 | Frankfurt am Main | Central Station | 11:30 | Prague | Wilsonova Coach Station | Economy | £23 |
A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 17/09/2026 01:40:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 17/09/2026 11:30:00. 50 Economy ticket for £23 per person are available. Travel duration is 9h 50m
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| FlixBus | 8h 15m | 01:50 | Frankfurt am Main | Central Station | 10:05 | Prague | Na Knížecí Station | Economy | £23 |
A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 17/09/2026 01:50:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 17/09/2026 10:05:00. 50 Economy ticket for £23 per person are available. Travel duration is 8h 15m
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| FlixBus | 10h 0m | 02:45 | Frankfurt am Main | Central Station | 12:45 | Prague | Na Knížecí Station | Economy | £23 |
A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 17/09/2026 02:45:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 17/09/2026 12:45:00. 50 Economy ticket for £23 per person are available. Travel duration is 10h 0m
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| FlixBus | 7h 30m | 01:50 | Frankfurt am Main | Central Station | 09:20 | Prague | ÚAN Florenc | Economy | £23 |
A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 17/09/2026 01:50:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 17/09/2026 09:20:00. 50 Economy ticket for £23 per person are available. Travel duration is 7h 30m
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| FlixBus | 7h 55m | 11:15 | Frankfurt am Main | Central Station | 19:10 | Prague | Na Knížecí Station | Economy | £24 |
A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 17/09/2026 11:15:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 17/09/2026 19:10:00. 50 Economy ticket for £24 per person are available. Travel duration is 7h 55m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 7h 25m | 17:20 | Frankfurt am Main | Central Station | 00:45 | Prague | Wilsonova Coach Station | Economy | £30 |
A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 18/09/2026 17:20:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 19/09/2026 00:45:00. 50 Economy ticket for £30 per person are available. Travel duration is 7h 25m
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| FlixBus | 8h 10m | 13:00 | Frankfurt am Main | Central Station | 21:10 | Prague | Na Knížecí Station | Economy | £30 |
A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 18/09/2026 13:00:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 18/09/2026 21:10:00. 50 Economy ticket for £30 per person are available. Travel duration is 8h 10m
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| FlixBus | 7h 10m | 17:20 | Frankfurt am Main | Central Station | 00:30 | Prague | Na Knížecí Station | Economy | £30 |
A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 18/09/2026 17:20:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 19/09/2026 00:30:00. 50 Economy ticket for £30 per person are available. Travel duration is 7h 10m
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| FlixBus | 8h 30m | 13:00 | Frankfurt am Main | Central Station | 21:30 | Prague | ÚAN Florenc | Economy | £30 |
A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 18/09/2026 13:00:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 18/09/2026 21:30:00. 50 Economy ticket for £30 per person are available. Travel duration is 8h 30m
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| FlixBus | 9h 50m | 01:40 | Frankfurt am Main | Central Station | 11:30 | Prague | Wilsonova Coach Station | Economy | £31 |
A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 18/09/2026 01:40:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 18/09/2026 11:30:00. 50 Economy ticket for £31 per person are available. Travel duration is 9h 50m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 9h 55m | 06:05 | Frankfurt am Main | Central Station | 16:00 | Prague | Wilsonova Coach Station | Economy | £27 |
A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 19/09/2026 06:05:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 19/09/2026 16:00:00. 50 Economy ticket for £27 per person are available. Travel duration is 9h 55m
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| FlixBus | 7h 55m | 04:50 | Frankfurt am Main | Central Station | 12:45 | Prague | Na Knížecí Station | Economy | £27 |
A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 19/09/2026 04:50:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 19/09/2026 12:45:00. 50 Economy ticket for £27 per person are available. Travel duration is 7h 55m
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| FlixBus | 9h 30m | 22:00 | Frankfurt am Main | Central Station | 07:30 | Prague | Hradčanská | Economy | £27 |
A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 19/09/2026 22:00:00 to Hradčanská, Prague (Czech Republic) arriving at 20/09/2026 07:30:00. 50 Economy ticket for £27 per person are available. Travel duration is 9h 30m
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| FlixBus | 7h 25m | 17:20 | Frankfurt am Main | Central Station | 00:45 | Prague | Wilsonova Coach Station | Economy | £29 |
A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 19/09/2026 17:20:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 20/09/2026 00:45:00. 50 Economy ticket for £29 per person are available. Travel duration is 7h 25m
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| FlixBus | 8h 10m | 13:00 | Frankfurt am Main | Central Station | 21:10 | Prague | Na Knížecí Station | Economy | £29 |
A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 19/09/2026 13:00:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 19/09/2026 21:10:00. 50 Economy ticket for £29 per person are available. Travel duration is 8h 10m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 7h 25m | 06:05 | Frankfurt am Main | Central Station | 13:30 | Prague | ÚAN Florenc | Economy | £30 |
A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 20/09/2026 06:05:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 20/09/2026 13:30:00. 50 Economy ticket for £30 per person are available. Travel duration is 7h 25m
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| FlixBus | 9h 50m | 01:40 | Frankfurt am Main | Central Station | 11:30 | Prague | Wilsonova Coach Station | Economy | £31 |
A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 20/09/2026 01:40:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 20/09/2026 11:30:00. 50 Economy ticket for £31 per person are available. Travel duration is 9h 50m
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| FlixBus | 9h 30m | 01:50 | Frankfurt am Main | Central Station | 11:20 | Prague | Wilsonova Coach Station | Economy | £31 |
A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 20/09/2026 01:50:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 20/09/2026 11:20:00. 50 Economy ticket for £31 per person are available. Travel duration is 9h 30m
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| FlixBus | 9h 55m | 06:05 | Frankfurt am Main | Central Station | 16:00 | Prague | Wilsonova Coach Station | Economy | £31 |
A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 20/09/2026 06:05:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 20/09/2026 16:00:00. 50 Economy ticket for £31 per person are available. Travel duration is 9h 55m
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| FlixBus | 8h 15m | 01:50 | Frankfurt am Main | Central Station | 10:05 | Prague | Na Knížecí Station | Economy | £31 |
A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 20/09/2026 01:50:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 20/09/2026 10:05:00. 50 Economy ticket for £31 per person are available. Travel duration is 8h 15m
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FlixBus8h 35m009:00Frankfurt am MainCentral Station13:15BayreuthCentral Station0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 21/09/2026 09:00:00 to Central Station, Bayreuth (Germany) arriving at 21/09/2026 13:15:00. 50 Economy ticket for £11 per person are available. Travel duration is 4h 15m
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FlixBus3h 40m013:55BayreuthCentral Station17:35PragueHradčanská0EconomyA Bus from FlixBus goes from Central Station, Bayreuth (Germany) at 21/09/2026 13:55:00 to Hradčanská, Prague (Czech Republic) arriving at 21/09/2026 17:35:00. 50 Economy ticket for £13 per person are available. Travel duration is 3h 40m
Waiting Time 0h 40m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 7h 55m | 11:15 | Frankfurt am Main | Central Station | 19:10 | Prague | Na Knížecí Station | Economy | £23 |
A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 21/09/2026 11:15:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 21/09/2026 19:10:00. 50 Economy ticket for £23 per person are available. Travel duration is 7h 55m
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| FlixBus | 8h 10m | 13:00 | Frankfurt am Main | Central Station | 21:10 | Prague | Na Knížecí Station | Economy | £23 |
A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 21/09/2026 13:00:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 21/09/2026 21:10:00. 50 Economy ticket for £23 per person are available. Travel duration is 8h 10m
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| FlixBus | 8h 20m | 11:15 | Frankfurt am Main | Central Station | 19:35 | Prague | ÚAN Florenc | Economy | £23 |
A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 21/09/2026 11:15:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 21/09/2026 19:35:00. 50 Economy ticket for £23 per person are available. Travel duration is 8h 20m
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| FlixBus | 8h 30m | 13:00 | Frankfurt am Main | Central Station | 21:30 | Prague | ÚAN Florenc | Economy | £23 |
A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 21/09/2026 13:00:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 21/09/2026 21:30:00. 50 Economy ticket for £23 per person are available. Travel duration is 8h 30m
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| FlixBus | 7h 25m | 17:20 | Frankfurt am Main | Central Station | 00:45 | Prague | Wilsonova Coach Station | Economy | £24 |
A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 21/09/2026 17:20:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 22/09/2026 00:45:00. 50 Economy ticket for £24 per person are available. Travel duration is 7h 25m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 9h 50m | 01:40 | Frankfurt am Main | Central Station | 11:30 | Prague | Wilsonova Coach Station | Economy | £22 |
A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 22/09/2026 01:40:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 22/09/2026 11:30:00. 50 Economy ticket for £22 per person are available. Travel duration is 9h 50m
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| FlixBus | 9h 30m | 01:50 | Frankfurt am Main | Central Station | 11:20 | Prague | Wilsonova Coach Station | Economy | £22 |
A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 22/09/2026 01:50:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 22/09/2026 11:20:00. 50 Economy ticket for £22 per person are available. Travel duration is 9h 30m
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| FlixBus | 9h 55m | 06:05 | Frankfurt am Main | Central Station | 16:00 | Prague | Wilsonova Coach Station | Economy | £22 |
A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 22/09/2026 06:05:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 22/09/2026 16:00:00. 50 Economy ticket for £22 per person are available. Travel duration is 9h 55m
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| KLR Bus | 13h 20m | 18:30 | Frankfurt am Main | Central Station | 07:50 | Prague | ÚAN Florenc | Economy | £29 |
A Bus from KLR Bus goes from Central Station, Frankfurt am Main (Germany) at 22/09/2026 18:30:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 23/09/2026 07:50:00. 50 Economy ticket for £29 per person are available. Travel duration is 13h 20m
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Best Price Offer: The price for the cheapest coach from Frankfurt am Main to Prague is £19 on 16/09/2026. Flexible travellers save on ticket prices.
What is the best day and time to travel by bus between Frankfurt am Main and Prague?
All facts for Frankfurt am Main to Prague bus at a glance
Compare all coach operators like FlixBus and KLR Bus that travel daily 18 times by bus from Frankfurt am Main to Prague in one click. Book your Frankfurt am Main to Prague bus ticket starting from £19!
| Cheapest Bus | £19 |
| Fastest Bus | 6h 56m |
| Earliest Coach | 06:05 |
| Latest Coach | 23:59 |
| Daily Bus Connections | 18 Ø |
| Distance | 410.5 km |
| Coach Companies | FlixBus and KLR Bus |
What are the cheapest coach tickets from Frankfurt am Main to Prague?
Every day, 18 buses from 2 coach companies leave Frankfurt am Main for Prague. Check the table below to find the cheapest prices for coach tickets for this route, starting from 16/09/2026 and for the following days. Make sure get the cheapest bus ticket!
The cheapest time to travel from Frankfurt am Main to Prague
How to save money travelling from Frankfurt am Main to Prague
Book the ticket from Frankfurt am Main to Prague in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the coach from Frankfurt am Main to Prague, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Frankfurt am Main to Prague are also emptier.Check for bus deals and promotions for all bus companies in this route. On CheckMyBus we show special offers directly in the coach trip on our search. Sign-up and check or deals sections and get notifications on our latest travel hacks.
All bus stations and stops in Frankfurt am Main and Prague
Here is a map with all coach stations in Frankfurt am Main and Prague. Compare which stop is closest to your destination to save time to find the fastest buses and connections.
Compare the bus with other modes of transport
All you need to know when you travel by bus from Frankfurt am Main to Prague
FAQs for Frankfurt am Main to Prague bus
How much does a Frankfurt am Main Prague coach trip cost?
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How long does a bus to Prague from Frankfurt am Main take?
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Which bus companies serve the Frankfurt am Main Prague route?
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Available seat classes which are offered on the bus route Frankfurt am Main to Prague
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
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